Home Aminos Phenothiazin-5-ium, 3-amino-7-(dimethylamino)-2-methyl-, chloride

Phenothiazin-5-ium, 3-amino-7-(dimethylamino)-2-methyl-, chloride

CAS No.:
92-31-9
Catalog Number:
AG00ILL0
Molecular Formula:
C15H16ClN3S
Molecular Weight:
305.8256
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
In Stock USA
United States
$48
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5g
In Stock USA
United States
$73
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25g
In Stock USA
United States
$151
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Product Description
Catalog Number:
AG00ILL0
Chemical Name:
Phenothiazin-5-ium, 3-amino-7-(dimethylamino)-2-methyl-, chloride
CAS Number:
92-31-9
Molecular Formula:
C15H16ClN3S
Molecular Weight:
305.8256
MDL Number:
MFCD00011934
IUPAC Name:
(7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium;chloride
InChI:
InChI=1S/C15H15N3S.ClH/c1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13;/h4-8,16H,1-3H3;1H
InChI Key:
GEDVVYWLPUPJJZ-UHFFFAOYSA-N
SMILES:
Cc1cc2nc3ccc(=[N+](C)C)cc3sc2cc1N.[Cl-]
EC Number:
202-146-2
UNII:
15XUH0X66N
Properties
Complexity:
512  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
305.075g/mol
Formal Charge:
0
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
305.824g/mol
Monoisotopic Mass:
305.075g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
66.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
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Histochemical analysis of pathological alterations in oral lichen planus and oral lichenoid lesions. Journal of oral science 20061201
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Different photoresponses of Staphylococcus aureus and Pseudomonas aeruginosa to 514, 532, and 633 nm low level lasers in vitro. Current microbiology 20061001
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Radical graft polymerization of styrene sulfonate on poly(ethylene terephthalate) films for ACL applications: 'grafting from' and chemical characterization. Biomacromolecules 20060301
The use of routine special stains for upper gastrointestinal biopsies. The American journal of surgical pathology 20060301
Low-potential nicotinamide adenine dinucleotide detection at a glassy carbon electrode modified with toluidine blue O functionalized multiwall carbon nanotubes. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060301
Photosensitization of in vitro biofilms by toluidine blue O combined with a light-emitting diode. European journal of oral sciences 20060201
Toluidine blue uptake in potentially malignant oral lesions in vivo: clinical and histological assessment. Oral oncology 20060101
Topo-optical visualization reactions of carbohydrate-containing amyloid deposits in the respiratory tract. Acta histochemica 20060101
Efficacy of gene transfer through the round window membrane: an in vitro model. ORL; journal for oto-rhino-laryngology and its related specialties 20060101
[Determination of nucleic acids using toluidine blue as a fluorescence probe]. Guang pu xue yu guang pu fen xi = Guang pu 20060101
Diagnostic accuracy of toluidine blue-stained wet films in effusion cytology. Acta cytologica 20060101
[Toluidine blue in monitoring of recurrences and second primary tumors in patients treated for oral cavity and pharynx cancer]. Otolaryngologia polska = The Polish otolaryngology 20060101
Photodynamic inactivation of in vitro bacterial cultures from pressure ulcers. Acta cirurgica brasileira 20060101
Immunohistochemical characteristics of developing mandibular angle in fetal mice. European journal of medical research 20051207
Morphological and immunocytochemical investigations on mast cells in porcine ureter. Anatomia, histologia, embryologia 20051201
Toluidine positivity in chromophobe renal cell carcinoma: use in intraoperative diagnosis. Histopathology 20051101
Visualization of intraarticular structures of the acromioclavicular joint in an ex vivo model using a dedicated MRI protocol. AJR. American journal of roentgenology 20051101
Staining of the Reinke crystalloids in the human testis--re-evaluation study. Okajimas folia anatomica Japonica 20051101
Cationic fullerenes are effective and selective antimicrobial photosensitizers. Chemistry & biology 20051001
Induction of interleukin-6 in dorsal root ganglion neurons after gradual elongation of rat sciatic nerve. Experimental neurology 20050901
Toluidine blue staining identifies high-risk primary oral premalignant lesions with poor outcome. Cancer research 20050901
Histochemical and topo-optical investigations on tissue-isolated and in vitro amyloid fibrils. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20050901
Pranlukast, a cysteinyl leukotriene receptor-1 antagonist, protects against chronic ischemic brain injury and inhibits the glial scar formation in mice. Brain research 20050816
Susceptibility of Streptococcus mutans biofilms to photodynamic therapy: an in vitro study. The Journal of antimicrobial chemotherapy 20050801
Chemopreventive and therapeutic efficacy of orally active tyrosine kinase inhibitors in a transgenic mouse model of gallbladder carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 20050801
Chemiluminescence as a diagnostic aid in the detection of oral cancer and potentially malignant epithelial lesions. International journal of oral and maxillofacial surgery 20050701
Simultaneous detection of submicrogram quantities of hyaluronic acid and dermatan sulfate on agarose-gel by sequential staining with toluidine blue and Stains-All. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050605
808-nm laser with exogenous chromophores for the treatment of benign oral lesions. Photomedicine and laser surgery 20050601
Virulence of Pseudomonas aeruginosa cells surviving photodynamic treatment with toluidine blue. Current microbiology 20050501
Tamoxifen stimulates cancellous bone formation in long bones of female mice. Endocrinology 20050301
Assessment of nerve degeneration by gadofluorine M-enhanced magnetic resonance imaging. Annals of neurology 20050301
Electrochemical sensing platform based on the carbon nanotubes/redox mediators-biopolymer system. Journal of the American Chemical Society 20050223
Dynamics of carbohydrate affinities at the cell surface of capacitating bovine sperm cells. Biology of reproduction 20050201
Identification of quenchers of photoexcited States as novel agents for skin photoprotection. The Journal of pharmacology and experimental therapeutics 20050201
Rapid toluidine blue stain for Mohs' micrographic surgery. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20050201
A system for studying epithelial-stromal interactions reveals distinct inductive abilities of stromal cells from benign prostatic hyperplasia and prostate cancer. Endocrinology 20050101
Study of the cost-effectiveness of three staining methods for identification of Pneumocystis carinii in bronchoalveolar lavage fluid. Tropical doctor 20050101
Interstitial cells of Cajal in pancreas. Journal of cellular and molecular medicine 20050101
Combining multispectral polarized light imaging and confocal microscopy for localization of nonmelanoma skin cancer. Journal of biomedical optics 20050101
[Screening the at-risk population for squamous cell carcinoma of the esophagus]. Gastroenterologia y hepatologia 20050101
Glutamic acid decarboxylase and GABA immunoreactivities in the cerebellar cortex of adult rat after prenatal exposure to a low concentration of carbon monoxide. Neuroscience 20050101
Degranulating mast cells in fibrotic regions of human tumors and evidence that mast cell heparin interferes with the growth of tumor cells through a mechanism involving fibroblasts. BMC cancer 20050101
Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro. Arthritis research & therapy 20050101
Effects of distinct classes of N-methyl-D-aspartate receptor antagonists on seizures, axonal sprouting and neuronal loss in vitro: suppression by NR2B-selective antagonists. Neuropharmacology 20041201
Combination of toluidine blue staining and in situ hybridization to evaluate paraffin tissue sections. Cancer genetics and cytogenetics 20041101
Toluidine blue cytometry test for sperm DNA conformation: comparison with the flow cytometric sperm chromatin structure and TUNEL assays. Human reproduction (Oxford, England) 20041001
Multilayer assembly of Prussian blue nanoclusters and enzyme-immobilized poly(toluidine blue) films and its application in glucose biosensor construction. Langmuir : the ACS journal of surfaces and colloids 20040817
Comparison between the toluidine blue stain and the Feulgen reaction for evaluation of rabbit sperm chromatin condensation and their relationship with sperm morphology. Theriogenology 20040801
The analysis of pyridylamino-dextran sulfate oligomers by high-performance liquid chromatography and a novel detection system for sulfated polysaccharides. Oncology reports 20040801
The anatomical rationale for an upper limb sympathetic blockade: preliminary report. Surgical and radiologic anatomy : SRA 20040601
Simvastatin promotes osteogenesis around titanium implants. Clinical oral implants research 20040601
Quantification of polyphosphate: different sensitivities to short-chain polyphosphate using enzymatic and colorimetric methods as revealed by ion chromatography. Analytical biochemistry 20040515
Significance of toluidine blue positive findings after speculum examination for sexual assault. The American journal of emergency medicine 20040501
Localization of mast cells in endometrial cysts. American journal of reproductive immunology (New York, N.Y. : 1989) 20040501
Extraction of heparin and heparin-like substance from marine mesogastropod mollusc Turritella attenuata (Lamarck, 1779). Indian journal of experimental biology 20040501
Increased expression of mast cells in reflux nephropathy. Pediatric nephrology (Berlin, Germany) 20040201
The distribution of mast cells in the human area postrema. Journal of anatomy 20040201
[Determination of deoxyribonucleic acids at nanograms levels with toluidine blue by a resonance light-scattering method]. Guang pu xue yu guang pu fen xi = Guang pu 20040201
Compatibility of staining protocols for bone tissue with Raman imaging. Calcified tissue international 20040101
A new method for rapid visualization of defects in leaf cuticle reveals five intrinsic patterns of surface defects in Arabidopsis. The Plant journal : for cell and molecular biology 20040101
Effect of enamel matrix derivative (Emdogain) on bone defects in rabbit tibias. The Journal of oral implantology 20040101
The photo-activated antibacterial action of toluidine blue O in a collagen matrix and in carious dentine. Caries research 20040101
Detection of submicrogram quantities of Escherichia coli lipopolysaccharides by agarose-gel electrophoresis. Analytical biochemistry 20031115
A one-step dual-labeling method for antigen detection in mast cells. Histochemistry and cell biology 20031101
Quantitative analysis of tryptase- and chymase-containing mast cells in eosinophilic conditions of cats. Veterinary pathology 20031101
The role of the methylene blue and toluidine blue monomers and dimers in the photoinactivation of bacteria. Journal of photochemistry and photobiology. B, Biology 20031015
The effectiveness of community-based visual screening and utility of adjunctive diagnostic aids in the early detection of oral cancer. Oral oncology 20031001
Malachite green and phthalocyanine-silver reactions reveal acidic phospholipid involvement in calcification of porcine aortic valves in rat subdermal model. Histology and histopathology 20031001
Microleakage of a single-bottle adhesive system with 3 restorative materials: in vitro study and clinical considerations. Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) 20031001
A new technique for staining mast cells using ferroin. Biotechnic & histochemistry : official publication of the Biological Stain Commission 20031001
Rapid staining using toluidine blue: a reliable method for quick diagnosis in ultrasound-guided aspiration cytology. Indian journal of pathology & microbiology 20031001
Retinal remodeling triggered by photoreceptor degenerations. The Journal of comparative neurology 20030908
Lethal photosensitization of periodontal pathogens by a red-filtered Xenon lamp in vitro. Journal of periodontal research 20030801
Demarcation of nonmelanoma skin cancer margins in thick excisions using multispectral polarized light imaging. The Journal of investigative dermatology 20030801
Comparative antistreptococcal activity of photobactericidal agents. Journal of chemotherapy (Florence, Italy) 20030801
Imprint cytology of axillary lymph nodes as an intraoperative diagnostic tool. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20030401
Study of mast cells in non-neoplastic skin lesions. Indian journal of pathology & microbiology 20030401
Toluidine blue test for sperm DNA integrity and elaboration of image cytometry algorithm. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20030301
Quantitative analysis of tryptase- and chymase-containing mast cells in eosinophilic conditions of cats. Veterinary pathology 20030301
Treatment of ligature-induced peri-implantitis by lethal photosensitization and guided bone regeneration: a preliminary histologic study in dogs. Journal of periodontology 20030301
Lethal photosensitization in microbiological treatment of ligature-induced peri-implantitis: a preliminary study in dogs. Journal of oral science 20030301
[Intraoperative histological sections in obstetric brachial plexus lesions--comparison of macroscopic appearance, HE staining and toluidine blue staining]. Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... 20030301
Electrospray mass spectra of group 6 (Fischer) carbenes in the presence of electron-donor compounds. Journal of mass spectrometry : JMS 20030201
Compensatory bone formation in young and old rats during tooth movement. European journal of orthodontics 20030201
Increased allelic loss in toluidine blue-positive oral premalignant lesions. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20030101
Changes in urinary bone resorption markers (pyridinoline, deoxypyridinoline) resulting from experimentally-induced osteoarthritis in the temporomandibular joint of rats. Cranio : the journal of craniomandibular practice 20030101
Dyes in dermatology. Clinics in dermatology 20030101
The porcine ear skin as a model system for the human integument: influence of storage conditions on basic features of epidermis structure and function--a histological and histochemical study. Polish journal of veterinary sciences 20030101
Techniques for the study of apoptosis in bone. Methods in molecular medicine 20030101
The effect of variable energy input from a novel light source on the photoactivated bactericidal action of toluidine blue O on Streptococcus Mutans. Caries research 20030101
Jejunal atresia related to the use of toluidine blue in genetic amniocentesis in twins. Journal of perinatal medicine 20030101
The dog mast cell tumour as a model to study the relationship between angiogenesis, mast cell density and tumour malignancy. Oncology reports 20030101
Study of solar photosensitization processes on dermatophytic fungi. Acta microbiologica Polonica 20030101
The interaction of lipopolysaccharides with phenothiazine dyes. Lasers in surgery and medicine 20030101
Detection of submicrogram quantities of glycosaminoglycans on agarose gels by sequential staining with toluidine blue and Stains-All. Electrophoresis 20021201
Advances in the diagnosis of oral premalignant and malignant lesions. Journal (Canadian Dental Association) 20021101
Photodynamic therapy with toluidine blue in Jurkat cells: cytotoxicity, subcellular localization and apoptosis induction. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20021101
A nonradioactive method for the assay of polyphosphate kinase activity and its application in the study of polyphosphate metabolism in Burkholderia cepacia. Analytical biochemistry 20020915
Exposure of Porphyromonas gingivalis to red light in the presence of the light-activated antimicrobial agent toluidine blue decreases membrane fluidity. Current microbiology 20020801
Contrast agents for confocal microscopy: how simple chemicals affect confocal images of normal and cancer cells in suspension. Journal of biomedical optics 20020701
Comparison of methods for identification of Pneumocystis carinii in bronchoalveolar lavage fluid. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020601
Amperometric urea biosensor based on urease and electropolymerized toluidine blue dye as a pH-sensitive redox probe. Bioelectrochemistry (Amsterdam, Netherlands) 20020515
An in vitro comparison of the bactericidal efficacy of lethal photosensitization or sodium hyphochlorite irrigation on Streptococcus intermedius biofilms in root canals. International endodontic journal 20020301
Improved demonstration of mast cells using alcian blue tetrakis (methylpyridium) chloride. Biotechnic & histochemistry : official publication of the Biological Stain Commission 20020301
Factors influencing the susceptibility of Gram-negative bacteria to toluidine blue O-mediated lethal photosensitization. Journal of applied microbiology 20020101
The effect of toluidine blue on the survival, dormancy and outer membrane porin proteins (OmpC and OmpF) of Salmonella typhimurium LT2 in seawater. Journal of applied microbiology 20020101
Fluorescence biodistribution and photosensitising activity of toluidine blue o on rat buccal mucosa. Lasers in medical science 20020101
Oral bacteria in multi-species biofilms can be killed by red light in the presence of toluidine blue. Lasers in surgery and medicine 20020101
Characterization of bone around titanium implants and bioactive glass particles: an experimental study in rats. The International journal of oral & maxillofacial implants 20020101
Bone response to machined and resorbable blast material titanium implants: an experimental study in rabbits. The Journal of oral implantology 20020101
Mast cell infiltration in the wall of varicose veins. Acta histochemica 20020101
Light and scanning electron microscopic studies of the angioarchitecture of intrinsic muscle fibers of the anterior rat tongue. Journal of oral science 20011201
Attachment of human periodontal ligament cells to enamel matrix-derived protein is mediated via interaction between BSP-like molecules and integrin alpha(v)beta3. Journal of periodontology 20011101
Immediate implantation in fresh extraction sockets. A controlled clinical and histological study in man. Journal of periodontology 20011101
Cardiac and ocular manifestations in Egyptian patients with mucopolysaccharidoses. Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20011101
Pale vacuolated epithelial cells in epididymis of aflatoxin-treated mice. Reproduction (Cambridge, England) 20011001
Administration of osteocalcin accelerates orthodontic tooth movement induced by a closed coil spring in rats. European journal of orthodontics 20011001
Metachromasia of the endocervical epithelium in women treated with gonadotropin releasing hormone agonist. International journal of molecular medicine 20010901
The difference in E-cadherin expression between nonvascularized and vascularized nerve grafts: study in the rat sciatic nerve model. The Journal of surgical research 20010901
Fluids and microbial penetration in the internal part of cement-retained versus screw-retained implant-abutment connections. Journal of periodontology 20010901
Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice. The Journal of pharmacology and experimental therapeutics 20010801
Diagnosis and management of oral soft-tissue lesions: the use of biopsy, toluidine blue staining, and brush biopsy. Journal of the California Dental Association 20010801
Acute basophilic leukemia. European journal of haematology 20010801
Cyclosporin-induced gingival overgrowth at the newly formed edentulous ridge in rats: a morphological and histometric evaluation. Journal of periodontology 20010701
Azithromycin, a lysosomotropic antibiotic, impairs fluid-phase pinocytosis in cultured fibroblasts. European journal of cell biology 20010701
Pulmonary reduction of an intravascular redox polymer. American journal of physiology. Lung cellular and molecular physiology 20010601
The influence of static and dynamic loading on marginal bone reactions around osseointegrated implants: an animal experimental study. Clinical oral implants research 20010601
Cartilage-like phenomenon in the anterior cruciate ligamenta. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20010601
Determination of heparin on intraocular lens surfaces by ion chromatography. Journal of chromatography. A 20010511
Reliability of toluidine blue application in the detection of oral epithelial dysplasia and in situ and invasive squamous cell carcinomas. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20010501
Effects of cyclosporin A on dental alveolar bone: a histomorphometric study in rats. Journal of periodontology 20010501
Roles of mast cells and histamine in mosquito bite-induced allergic itch-associated responses in mice. Japanese journal of pharmacology 20010501
Counterstaining and mounting of autoradiographed in situ hybridization slides. Current protocols in molecular biology 20010501
Lethal photosensitization for decontamination of implant surfaces in the treatment of peri-implantitis. Clinical oral implants research 20010401
Cytotoxicity testing with three-dimensional cultures of transfected pulp-derived cells. Journal of endodontics 20010401
Biocompatibility of silicon-based arrays of electrodes coupled to organotypic hippocampal brain slice cultures. Brain research 20010330
A histomorphometric study of the tissue reaction around hydroxyapatite implants irradiated after placement. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20010301
Osseintegration following treatment of peri-implantitis and replacement of implant components. An experimental study in the dog. Journal of clinical periodontology 20010301
Metachromasia of the endocervical epithelium for delineating the internal os. The Journal of reproductive medicine 20010201
Wet and dry deep cavity preparations compared by a novel odontoblast culture technique. Journal of endodontics 20010201
Acute stress increases permeability of the blood-brain-barrier through activation of brain mast cells. Brain research 20010105
Comparative study of cytochemical tests for sperm chromatin integrity. Journal of andrology 20010101
A case of pulmonary acariasis in lung of Japanese macaque. The Journal of veterinary medical science 20010101
Establishment and characterization of a murine mast cell line derived from NC/Nga mice. International archives of allergy and immunology 20010101
Comparison of the methylene blue and toluidine blue photobactericidal efficacy against gram-positive and gram-negative microorganisms. Lasers in surgery and medicine 20010101
Ribonuclease assays utilizing toluidine blue indicator plates, methylene blue, or fluorescence correlation spectroscopy. Methods in enzymology 20010101
Effect of proline on the production of singlet oxygen. Amino acids 20010101
Evaluation of mast cells in oral lichen planus and oral lichenoid reaction. Indian journal of dental research : official publication of Indian Society for Dental Research 20010101
[Chromoendoscopy in the diagnosis of precancerous lesions of the esophagus. Our experience]. Annali italiani di chirurgia 20010101
Influence of age and gender on peri-implant osteogenesis. Age and gender on peri-implant osteogenesis. Acta odontologica latinoamericana : AOL 20010101
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