Home Aminos [(E)-[(pyridin-2-yl)methylidene]amino]thiourea

[(E)-[(pyridin-2-yl)methylidene]amino]thiourea

CAS No.:
61043-10-5
Catalog Number:
AG00IXCH
Molecular Formula:
C7H8N4S
Molecular Weight:
180.2302
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Product Description
Catalog Number:
AG00IXCH
Chemical Name:
[(E)-[(pyridin-2-yl)methylidene]amino]thiourea
CAS Number:
61043-10-5
Molecular Formula:
C7H8N4S
Molecular Weight:
180.2302
MDL Number:
MFCD00160323
IUPAC Name:
(pyridin-2-ylmethylideneamino)thiourea
InChI:
InChI=1S/C7H8N4S/c8-7(12)11-10-5-6-3-1-2-4-9-6/h1-5H,(H3,8,11,12)
InChI Key:
GXBCCUBTQFNGFA-UHFFFAOYSA-N
SMILES:
NC(=S)N/N=C/c1ccccn1
Properties
Complexity:
180  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
180.047g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
180.229g/mol
Monoisotopic Mass:
180.047g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
95.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
1  
XLogP3:
1.4  
Literature
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Bis(pyridine-2-carbaldehyde thio-semi-carbazone)zinc(II) dinitrate dihydrate. Acta crystallographica. Section E, Structure reports online 20101001
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Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation. Journal of medicinal chemistry 20090827
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Spectroscopic and biological approach of Ni(II) and Cu(II) complexes of 2-pyridinecarboxaldehyde thiosemicarbazone. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080301
Synthesis, characterization, and in vitro cytotoxic activities of benzaldehyde thiosemicarbazone derivatives and their palladium (II) and platinum (II) complexes against various human tumor cell lines. Bioinorganic chemistry and applications 20080101
Spectroscopic, thermal and biological studies on some trivalent ruthenium and rhodium NS chelating thiosemicarbazone complexes. Bioinorganic chemistry and applications 20070101
Platinum(II) and palladium(II) complexes of pyridine-2-carbaldehyde thiosemicarbazone as alternative antiherpes simplex virus agents. Bioinorganic chemistry and applications 20070101
Antimicrobial activity of two antitumour agents and ribonucleotide reductase inhibitors, pyridine-2-carboxaldehyde thiosemicarbazone and the acetate form of its copper(II) chelate. Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101
Zinc(II) complexes derived from pyridine-2-carbaldehyde thiosemicarbazone and (1E)-1-pyridin-2-ylethan-1-one thiosemicarbazone. Synthesis, crystal structures and antiproliferative activity of zinc(II) complexes. Journal of inorganic biochemistry 20060901
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Biological activity of complexes derived from pyridine-2-carbaldehyde thiosemicarbazone. Structure of. Journal of inorganic biochemistry 20010401
Antiviral activity of platinum (II) and palladium (II) complexes of pyridine-2-carbaldehyde thiosemicarbazone. Acta virologica 20010401
Properties