Name: Name:SGI-1027
Brand: Angene
SKU: AG0006BW
Rating: 90 (10 reviews)

SGI-1027

CAS No.:

1020149-73-8

Catalog Number:

AG0006BW

Molecular Formula:

C27H23N7O

Molecular Weight:

461.5178

Pack Size

Purity

Availability

Location

Price(USD)

Quantity

1mg

≥98%

1 week

United States

$97

- +

5mg

≥98%

1 week

United States

$178

- +

10mg

99%

1 week

United States

$229

- +

50mg

99%

1 week

United States

$572

- +

Product Description

Catalog Number:

AG0006BW

Chemical Name:

SGI-1027

CAS Number:

1020149-73-8

Molecular Formula:

C27H23N7O

Molecular Weight:

461.5178

MDL Number:

MFCD27937047

IUPAC Name:

N-[4-[(2-amino-6-methylpyrimidin-4-yl)amino]phenyl]-4-(quinolin-4-ylamino)benzamide

InChI:

InChI=1S/C27H23N7O/c1-17-16-25(34-27(28)30-17)32-20-10-12-21(13-11-20)33-26(35)18-6-8-19(9-7-18)31-24-14-15-29-23-5-3-2-4-22(23)24/h2-16H,1H3,(H,29,31)(H,33,35)(H3,28,30,32,34)

InChI Key:

QSYLKMKIVWJAAK-UHFFFAOYSA-N

SMILES:

Cc1cc(Nc2ccc(cc2)NC(=O)c2ccc(cc2)Nc2ccnc3c2cccc3)nc(n1)N

Properties

Complexity:

676

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

461.196g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

461.529g/mol

Monoisotopic Mass:

461.196g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

118A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

4.8

Literature

Title	Journal
New insights on the mechanism of quinoline-based DNA Methyltransferase inhibitors.	The Journal of biological chemistry 20150306
Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.	Journal of medicinal chemistry 20140213
Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.	The Journal of biological chemistry 20130816

Properties