Name: Name:1-Pyrenebutanol
Brand: Angene
SKU: AG003ENC
Rating: 90 (10 reviews)

Catalog Number:

AG003ENC

Chemical Name:

1-Pyrenebutanol

CAS Number:

67000-89-9

MDL Number:

MFCD00192423

IUPAC Name:

4-pyren-1-ylbutan-1-ol

InChI:

InChI=1S/C20H18O/c21-13-2-1-4-14-7-8-17-10-9-15-5-3-6-16-11-12-18(14)20(17)19(15)16/h3,5-12,21H,1-2,4,13H2

InChI Key:

MRENSFROWALQNU-UHFFFAOYSA-N

Complexity:

352

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

1

Defined Atom Stereocenter Count:

0

Defined Bond Stereocenter Count:

0

Exact Mass:

274.136g/mol

Formal Charge:

0

Heavy Atom Count:

21

Hydrogen Bond Acceptor Count:

1

Hydrogen Bond Donor Count:

1

Isotope Atom Count:

0

Molecular Weight:

274.363g/mol

Monoisotopic Mass:

274.136g/mol

Rotatable Bond Count:

4

Topological Polar Surface Area:

20.2A^2

Undefined Atom Stereocenter Count:

0

Undefined Bond Stereocenter Count:

0

XLogP3:

5.3

Title	Journal
Multiple substrate-binding sites are retained in cytochrome P450 3A4 mutants with decreased cooperativity.	Xenobiotica; the fate of foreign compounds in biological systems 20110401
Effect of glutathione on homo- and heterotropic cooperativity in cytochrome P450 3A4.	Archives of biochemistry and biophysics 20080315
Allosteric mechanisms in cytochrome P450 3A4 studied by high-pressure spectroscopy: pivotal role of substrate-induced changes in the accessibility and degree of hydration of the heme pocket.	Biochemistry 20070703
Role of subunit interactions in P450 oligomers in the loss of homotropic cooperativity in the cytochrome P450 3A4 mutant L211F/D214E/F304W.	Archives of biochemistry and biophysics 20070401
Mechanism of interactions of alpha-naphthoflavone with cytochrome P450 3A4 explored with an engineered enzyme bearing a fluorescent probe.	Biochemistry 20070109
Resolution of multiple substrate binding sites in cytochrome P450 3A4: the stoichiometry of the enzyme-substrate complexes probed by FRET and Job's titration.	Biochemistry 20060404
Resolution of two substrate-binding sites in an engineered cytochrome P450eryF bearing a fluorescent probe.	Biophysical journal 20050701
An electrostatically driven conformational transition is involved in the mechanisms of substrate binding and cooperativity in cytochrome P450eryF.	Biochemistry 20040601
Synthesis of a novel fluorescent poly(D,L-lactide) end-capped with 1-pyrenebutanol used for the preparation of nanoparticles.	European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20031001
Homotropic versus heterotopic cooperativity of cytochrome P450eryF: a substrate oxidation and spectral titration study.	Drug metabolism and disposition: the biological fate of chemicals 20030401
Allosteric mechanisms in P450eryF probed with 1-pyrenebutanol, a novel fluorescent substrate.	Biochemical and biophysical research communications 20020621