Home Other Building Blocks 2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one

2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one

CAS No.:
855-97-0
Catalog Number:
AG003IEB
Molecular Formula:
C19H18O6
Molecular Weight:
342.3426
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Product Description
Catalog Number:
AG003IEB
Chemical Name:
2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one
CAS Number:
855-97-0
Molecular Formula:
C19H18O6
Molecular Weight:
342.3426
MDL Number:
MFCD00017558
IUPAC Name:
2-(3,4-dimethoxyphenyl)-5,7-dimethoxychromen-4-one
InChI:
InChI=1S/C19H18O6/c1-21-12-8-17(24-4)19-13(20)10-15(25-18(19)9-12)11-5-6-14(22-2)16(7-11)23-3/h5-10H,1-4H3
InChI Key:
CLXVBVLQKLQNRQ-UHFFFAOYSA-N
SMILES:
COc1cc(OC)c2c(c1)oc(cc2=O)c1ccc(c(c1)OC)OC
Properties
Complexity:
504  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
342.11g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
342.347g/mol
Monoisotopic Mass:
342.11g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
63.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.1  
Literature
Title Journal
The O-methylation of chrysin markedly improves its intestinal anti-inflammatory properties: Structure-activity relationships of flavones. Biochemical pharmacology 20131215
Identification of 5,7,3',4'-tetramethoxyflavone metabolites in rat urine by the isotope-labeling method and ultrahigh-performance liquid chromatography-electrospray ionization-mass spectrometry. Journal of agricultural and food chemistry 20120822
Relationship between the structures of flavonoids and their NF-κB-dependent transcriptional activities. Bioorganic & medicinal chemistry letters 20111015
Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells. Bioorganic & medicinal chemistry 20110501
Xanthine oxidase inhibitory activities and crystal structures of methoxyflavones from Kaempferia parviflora rhizome. Biological & pharmaceutical bulletin 20110101
Chemical constituents from tiger's betel, Piper porphyrophyllum N.E.Br. (Fam. Piperaceae). Natural product research 20100301
Simultaneous identification and quantitation of 11 flavonoid constituents in Kaempferia parviflora by gas chromatography. Journal of chromatography. A 20070302
Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2. Biochemical pharmacology 20050215
Bioactive flavonoids from Kaempferia parviflora. Fitoterapia 20040101
Structural requirements of flavonoids for nitric oxide production inhibitory activity and mechanism of action. Bioorganic & medicinal chemistry 20030501
Reversal of P-glycoprotein-mediated multidrug resistance by 5,6,7,3',4'-pentamethoxyflavone (Sinensetin). Biochemical and biophysical research communications 20020726
Flavonolignan and flavone inhibitors of a Staphylococcus aureus multidrug resistance pump: structure-activity relationships. Journal of medicinal chemistry 20010118
Properties