DIHYDROFOLIC ACID
| Title | Journal |
|---|---|
| Multiple point action mechanism of valproic acid-teratogenicity alleviated by folic acid, vitamin C, and N-acetylcysteine in chicken embryo model. | Toxicology 20120127 |
| Distribution of quinolones, sulfonamides, tetracyclines in aquatic environment and antibiotic resistance in indochina. | Frontiers in microbiology 20120101 |
| Systematic review of disease-modifying antirheumatic drugs for juvenile idiopathic arthritis. | BMC pediatrics 20120101 |
| Accounting for differences in the bioactivity and bioavailability of vitamers. | Food & nutrition research 20120101 |
| Exploiting ligand-protein conjugates to monitor ligand-receptor interactions. | PloS one 20120101 |
| A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. | PloS one 20120101 |
| Evolutionarily conserved linkage between enzyme fold, flexibility, and catalysis. | PLoS biology 20111101 |
| Effect of genetic polymorphisms in the folate pathway on methotrexate therapy in rheumatic diseases. | Pharmacogenomics 20111001 |
| Comparative hydrogen-deuterium exchange for a mesophilic vs thermophilic dihydrofolate reductase at 25 °C: identification of a single active site region with enhanced flexibility in the mesophilic protein. | Biochemistry 20110927 |
| Multiple sclerosis: pathogenesis and treatment. | Current neuropharmacology 20110901 |
| Tea drinking as a risk factor for neural tube defects in northern China. | Epidemiology (Cambridge, Mass.) 20110701 |
| NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions. | Biochemistry 20110510 |
| Histidine hydrogen-deuterium exchange mass spectrometry for probing the microenvironment of histidine residues in dihydrofolate reductase. | PloS one 20110101 |
| Treatment of experimental adjuvant arthritis with a novel folate receptor-targeted folic acid-aminopterin conjugate. | Arthritis research & therapy 20110101 |
| On the curvature in logarithmic plots of rate coefficients for chemical reactions. | Chemistry Central journal 20110101 |
| Critical appraisal of pralatrexate in the management of difficult-to-treat peripheral T cell lymphoma. | Therapeutics and clinical risk management 20110101 |
| Systematic drug repositioning based on clinical side-effects. | PloS one 20110101 |
| Oral lichen planus: An update on pathogenesis and treatment. | Journal of oral and maxillofacial pathology : JOMFP 20110101 |
| Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition. | Molecular and biochemical parasitology 20100701 |
| Complete genomic sequence of bacteriophage felix o1. | Viruses 20100301 |
| Cobalamin deficiency, hyperhomocysteinemia, and dementia. | Neuropsychiatric disease and treatment 20100101 |
| [Photobiochemistry of folates: a photochemical reduction of folic acid]. | Prikladnaia biokhimiia i mikrobiologiia 20100101 |
| Dynamic subcellular localization of isoforms of the folate pathway enzyme serine hydroxymethyltransferase (SHMT) through the erythrocytic cycle of Plasmodium falciparum. | Malaria journal 20100101 |
| Management of Pneumocystis Jirovecii pneumonia in HIV infected patients: current options, challenges and future directions. | HIV/AIDS (Auckland, N.Z.) 20100101 |
| Antimicrobial evaluation of novel substituted pyrimidinopyrazoles and pyrimidinotriazoles. | Journal of advanced pharmaceutical technology & research 20100101 |
| Mechanistic insights into folic acid-dependent vascular protection: dihydrofolate reductase (DHFR)-mediated reduction in oxidant stress in endothelial cells and angiotensin II-infused mice: a novel HPLC-based fluorescent assay for DHFR activity. | Journal of molecular and cellular cardiology 20091201 |
| Binding of natural and synthetic polyphenols to human dihydrofolate reductase. | International journal of molecular sciences 20091201 |
| A mapping of drug space from the viewpoint of small molecule metabolism. | PLoS computational biology 20090801 |
| Voltammetric determination of sulfamethoxazole at a multiwalled carbon nanotube modified glassy carbon sensor and its application studies. | Drug testing and analysis 20090701 |
| (E)-N'-(3,3-Diphenyl-allyl-idene)-p-toluene-sulfonohydrazide. | Acta crystallographica. Section E, Structure reports online 20090501 |
| (E)-N'-(4-Chloro-benzyl-idene)-p-toluene-sulfonohydrazide 0.15-hydrate. | Acta crystallographica. Section E, Structure reports online 20090501 |
| (E)-N'-(4-Bromo-benzyl-idene)-p-toluene-sulfonohydrazide. | Acta crystallographica. Section E, Structure reports online 20090401 |
| QM/MM study of thymidylate synthase: enzymatic motions and the temperature dependence of the rate limiting step. | The journal of physical chemistry. A 20090312 |
| Regulation of translation in haloarchaea: 5'- and 3'-UTRs are essential and have to functionally interact in vivo. | PloS one 20090101 |
| (E)-N'-(5-Bromo-2-hydroxy-benzyl-idene)-p-toluene-sulfonohydrazide. | Acta crystallographica. Section E, Structure reports online 20081201 |
| (E)-N'-(5-Chloro-2-hydroxy-benzyl-idene)-p-toluene-sulfonohydrazide. | Acta crystallographica. Section E, Structure reports online 20081201 |
| (E)-N'-Benzyl-idene-p-toluene-sulfono-hydrazide. | Acta crystallographica. Section E, Structure reports online 20080901 |
| Metabolism of halophilic archaea. | Extremophiles : life under extreme conditions 20080301 |
| Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo. | PLoS neglected tropical diseases 20080301 |
| catena-Poly[bis-(sulfamethoxazolium) [[trichloridocadmate(II)]-μ-chlorido] monohydrate]. | Acta crystallographica. Section E, Structure reports online 20080101 |
| Experimental characterization of Cis-acting elements important for translation and transcription in halophilic archaea. | PLoS genetics 20071201 |
| Ligand binding and circular permutation modify residue interaction network in DHFR. | PLoS computational biology 20070601 |
| A functional 19-base pair deletion polymorphism of dihydrofolate reductase (DHFR) and risk of breast cancer in multivitamin users. | The American journal of clinical nutrition 20070401 |
| A quantum mechanics/molecular mechanics study of the catalytic mechanism of the thymidylate synthase. | Biochemistry 20070327 |
| Adenosine in inflammatory joint diseases. | Purinergic signalling 20070301 |
| Role of airway lactoperoxidase in scavenging of hydrogen peroxide damage in asthma. | Annals of thoracic medicine 20070101 |
| Protein motions during catalysis by dihydrofolate reductases. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20060829 |
| Folic acid and its metabolites modulate IGF-I receptor gene expression in colon cancer cells in a p53-dependent manner. | Endocrine-related cancer 20060601 |
| Sulfonamides in the environment as veterinary drugs. | Reviews of environmental contamination and toxicology 20060101 |
| Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression. | Arthritis research & therapy 20060101 |
| Kinetics of the inhibition of bovine liver dihydrofolate reductase by tea catechins: origin of slow-binding inhibition and pH studies. | Biochemistry 20050524 |
| The antifolate activity of tea catechins. | Cancer research 20050315 |
| Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1. | The protein journal 20050201 |
| Folate requirements of the 2-keto-L-gulonic acid-producing strain Ketogulonigenium vulgare LMP P-20356 in L-sorbose/CSL medium. | Applied microbiology and biotechnology 20040801 |
| Microscale synthesis of isotopically labeled R-[6-xH]N5,N10-methylene-5,6,7,8-tetrahydrofolate as a cofactor for thymidylate synthase. | Analytical biochemistry 20040501 |
| Sodium-dependent methotrexate carrier-1 is expressed in rat kidney: cloning and functional characterization. | American journal of physiology. Renal physiology 20040301 |
| Inhibition of the rat breast cytosolic bioactivation of ethanol to acetaldehyde by some plant polyphenols and folic acid. | Nutrition and cancer 20040101 |
| Reaction-path energetics and kinetics of the hydride transfer reaction catalyzed by dihydrofolate reductase. | Biochemistry 20031125 |
| Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima. | The Biochemical journal 20030901 |
| Role of water in the catalytic cycle of E. coli dihydrofolate reductase. | Protein science : a publication of the Protein Society 20020601 |
| Molecular action of methotrexate in inflammatory diseases. | Arthritis research 20020101 |
| Preliminary application of liquid chromatography-electrospray-ionization mass spectrometry to the detection of 5-methyltetrahydrofolic acid monoglutamate in human plasma. | Journal of chromatography. B, Biomedical sciences and applications 20011225 |
| Developing a dynamic pharmacophore model for HIV-1 integrase. | Journal of medicinal chemistry 20000601 |