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HT-2 Toxin

CAS No.:
26934-87-2
Catalog Number:
AG003QY7
Molecular Formula:
C22H32O8
Molecular Weight:
424.4847
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥99%
1 week
United States
$300
- +
5mg
≥99%
1 week
United States
$1090
- +
Product Description
Catalog Number:
AG003QY7
Chemical Name:
HT-2 Toxin
CAS Number:
26934-87-2
Molecular Formula:
C22H32O8
Molecular Weight:
424.4847
MDL Number:
MFCD00056784
IUPAC Name:
[(1S,2R,4S,7R,9R,10R,11S,12S)-2-(acetyloxymethyl)-10,11-dihydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate
InChI:
InChI=1S/C22H32O8/c1-11(2)6-16(24)29-14-8-21(9-27-13(4)23)15(7-12(14)3)30-19-17(25)18(26)20(21,5)22(19)10-28-22/h7,11,14-15,17-19,25-26H,6,8-10H2,1-5H3/t14-,15+,17+,18+,19+,20+,21+,22-/m0/s1
InChI Key:
PNKLMTPXERFKEN-MLXHEQMXSA-N
SMILES:
CC(CC(=O)O[C@H]1C[C@@]2(COC(=O)C)[C@@H](C=C1C)O[C@H]1[C@]3([C@]2(C)[C@H](O)[C@H]1O)CO3)C
UNII:
NC6C26RM46
Properties
Complexity:
777  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Defined Bond Stereocenter Count:
0
Exact Mass:
424.21g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
424.49g/mol
Monoisotopic Mass:
424.21g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
115A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.4  
Literature
Title Journal
Role of Peptide YY3-36 and Glucose-Dependent Insulinotropic Polypeptide in Anorexia Induction by Trichothecences T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol. Toxicological sciences : an official journal of the Society of Toxicology 20170901
Toxic effects of HT-2 toxin on mouse oocytes and its possible mechanisms. Archives of toxicology 20160601
Toxicity and oxidative stress induced by T-2 toxin and HT-2 toxin in broilers and broiler hepatocytes. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20160101
Toxicity induced by F. poae-contaminated feed and the protective effect of Montmorillonite supplementation in broilers. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20141201
An in vitro investigation of endocrine disrupting effects of trichothecenes deoxynivalenol (DON), T-2 and HT-2 toxins. Toxicology letters 20121115
Molecular studies to identify the Fusarium species responsible for HT-2 and T-2 mycotoxins in UK oats. International journal of food microbiology 20120515
Identification and characterization of new Fusarium masked mycotoxins, T2 and HT2 glycosyl derivatives, in naturally contaminated wheat and oats by liquid chromatography-high-resolution mass spectrometry. Journal of mass spectrometry : JMS 20120401
Development and validation of an LC-MS/MS method for the simultaneous determination of deoxynivalenol, zearalenone, T-2-toxin and some masked metabolites in different cereals and cereal-derived food. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101
Occurrence of Fusarium Head Blight species and Fusarium mycotoxins in winter wheat in the Netherlands in 2009. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101
Mycotoxin contamination of cereal grain commodities in relation to climate in North West Europe. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101
Effect of fenpropimorph, prochloraz and tebuconazole on growth and production of T-2 and HT-2 toxins by Fusarium langsethiae in oat-based medium. International journal of food microbiology 20111215
Observation of T-2 toxin and HT-2 toxin glucosides from Fusarium sporotrichioides by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). Toxins 20111201
A rapid fluorescence polarization immunoassay for the determination of T-2 and HT-2 toxins in wheat. Analytical and bioanalytical chemistry 20111101
Quantitative determination of T-2 toxin, HT-2 toxin, deoxynivalenol and deepoxy-deoxynivalenol in animal body fluids using LC-MS/MS detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110815
Incidence of Fusarium species and mycotoxins in silage maize. Toxins 20110801
Determination of type A and type B trichothecenes in paprika and chili pepper using LC-triple quadrupole-MS and GC-ECD. Talanta 20110530
Multi mycotoxin analysis in food products using immunoaffinity extraction. Methods in molecular biology (Clifton, N.J.) 20110101
Occurrence of Fusarium T-2 and HT-2 toxins in oats from cultivar studies in Germany and degradation of the toxins during grain cleaning treatment and food processing. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100901
Influence of barley malting operating parameters on T-2 and HT-2 toxinogenesis of Fusarium langsethiae, a worrying contaminant of malting barley in Europe. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100901
Different sample treatment approaches for the analysis of T-2 and HT-2 toxins from oats-based media. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100801
Less Fusarium infestation and mycotoxin contamination in organic than in conventional cereals. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100601
Fusarium mycotoxin content of UK organic and conventional oats. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090701
Metabolism and cytotoxic effects of T-2 toxin and its metabolites on human cells in primary culture. Toxicology 20090428
Effect of combined treatment with aflatoxin B1 and T-2 toxin and metabolites on some production traits and lipid peroxide status parameters of broiler chickens. Acta veterinaria Hungarica 20090301
Determination of T-2 and HT-2 toxins in cereals including oats after immunoaffinity cleanup by liquid chromatography and fluorescence detection. Journal of agricultural and food chemistry 20080709
Identification of fumonisin B2, HT-2 toxin, patulin, and zearalenone in dried figs by liquid chromatography-time-of-flight mass spectrometry and liquid chromatography-mass spectrometry. Journal of food protection 20080701
Determination of trichothecenes in cereals and cereal-based products by liquid chromatography-tandem mass spectrometry. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20080301
Mycotoxins in breakfast cereals from the Canadian retail market: a 3-year survey. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20080301
Improvement of detection sensitivity of T-2 and HT-2 toxins using different fluorescent labeling reagents by high-performance liquid chromatography. Talanta 20080215
Occurrence and fate of Fusarium mycotoxins during commercial processing of oats in the UK. Food additives and contaminants 20071201
Occurrence of type A trichothecenes in conventionally and organically produced oats and oat products. Molecular nutrition & food research 20071201
Structure-activity relationships of trichothecene toxins in an Arabidopsis thaliana leaf assay. Journal of agricultural and food chemistry 20070808
Phytotoxic effects of trichothecenes on the growth and morphology of Arabidopsis thaliana. Journal of experimental botany 20070101
Simultaneous determination of aflatoxins, ochratoxin A and Fusarium toxins in maize by liquid chromatography/tandem mass spectrometry after multitoxin immunoaffinity cleanup. Rapid communications in mass spectrometry : RCM 20070101
Measurement of T-2 and HT-2 toxins in eggs by high-performance liquid chromatography with fluorescence detection. Journal of food protection 20061101
Development of a multicomponent method for Fusarium toxins using LC-MS/MS and its application during a survey for the content of T-2 toxin and deoxynivalenol in various feed and food samples. Food additives and contaminants 20050801
A rapid multiresidual determination of type A and type B trichothecenes in wheat flour by HPLC-ESI-MS. Food additives and contaminants 20050301
Toxicity data relevant for hazard characterization. Toxicology letters 20041010
A practical method for measuring deoxynivalenol, nivalenol, and T-2 + HT-2 toxin in foods by an enzyme-linked immunosorbent assay using monoclonal antibodies. Bioscience, biotechnology, and biochemistry 20041001
Phylogenetic analyses of the Fusarium poae, Fusarium sporotrichioides and Fusarium langsethiae species complex based on partial sequences of the translation elongation factor-1 alpha gene. International journal of food microbiology 20040915
Deoxynivalenol and other Fusarium toxins in wheat and rye flours on the Danish market. Food additives and contaminants 20030401
Natural contamination of oat with group A trichothecene mycotoxins in Poland. Food additives and contaminants 20020501
Structural characterization of metabolites after the microbial degradation of type A trichothecenes by the bacterial strain BBSH 797. Food additives and contaminants 20020401
Fusarium toxins in wheat flour collected in an area in southwest Germany. International journal of food microbiology 20020130
Effect of time, temperature and solvent on the stability of T-2 toxin, HT-2 toxin, deoxynivalenol and nivalenol calibrants. Food additives and contaminants 20011101
Trichothecenes, ochratoxin A and zearalenone contamination and fusarium infection in Finnish cereal samples in 1998. Food additives and contaminants 20010801
Trichothecene toxicity on human megakaryocyte progenitors (CFU-MK). Human & experimental toxicology 20010201
Properties