5,8,11,14-Eicosatetraenoicacid, 20-hydroxy-, (5Z,8Z,11Z,14Z)-
| Title | Journal |
|---|---|
| Targeting of splice variants of human cytochrome P450 2C8 (CYP2C8) to mitochondria and their role in arachidonic acid metabolism and respiratory dysfunction. | The Journal of biological chemistry 20141024 |
| Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer. | Toxicology and applied pharmacology 20131001 |
| Tissue protection and endothelial cell signaling by 20-HETE analogs in intact ex vivo lung slices. | Experimental cell research 20121001 |
| Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer. | Toxicology and applied pharmacology 20121001 |
| Disturbed ratio of renal 20-HETE/EETs is involved in androgen-induced hypertension in cytochrome P450 4F2 transgenic mice. | Gene 20120901 |
| Increase of 20-HETE synthase after brain ischemia in rats revealed by PET study with 11C-labeled 20-HETE synthase-specific inhibitor. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120901 |
| Statins increase cytochrome P450 4F3-mediated eicosanoids production in human liver cells: a PXR dependent mechanism. | Biochemical pharmacology 20120815 |
| 20-HETE in neovascularization. | Prostaglandins & other lipid mediators 20120801 |
| Induction of angiotensin-converting enzyme and activation of the renin-angiotensin system contribute to 20-hydroxyeicosatetraenoic acid-mediated endothelial dysfunction. | Arteriosclerosis, thrombosis, and vascular biology 20120801 |
| Inhibitors of 20-hydroxyeicosatetraenoic acid (20-HETE) formation attenuate the natriuretic effect of dopamine. | European journal of pharmacology 20120705 |
| The circadian clock modulates renal sodium handling. | Journal of the American Society of Nephrology : JASN 20120601 |
| Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease. | Atherosclerosis 20120601 |
| Protective effect of 20-hydroxyeicosatetraenoic acid (20-HETE) on adriamycin-induced toxicity of human renal tubular epithelial cell (HK-2). | European journal of pharmacology 20120515 |
| Role of 20-HETE in the antihypertensive effect of transfer of chromosome 5 from Brown Norway to Dahl salt-sensitive rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20120515 |
| 20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel. | The Journal of biological chemistry 20120420 |
| Attenuation of neonatal ischemic brain damage using a 20-HETE synthesis inhibitor. | Journal of neurochemistry 20120401 |
| Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures. | American journal of physiology. Heart and circulatory physiology 20120315 |
| Evaluation of CMV and KAP promoters for driving the expression of human CYP4F2 in transgenic mice. | International journal of molecular medicine 20120101 |
| Testosterone-dependent increase in blood pressure is mediated by elevated Cyp4A expression in fructose-fed rats. | Molecular and cellular biochemistry 20120101 |
| Role of medullary blood flow in the pathogenesis of renal ischemia-reperfusion injury. | Current opinion in nephrology and hypertension 20120101 |
| Arachidonic acid inhibits Na⁺-K⁺-ATPase via cytochrome P-450, lipoxygenase and protein kinase C-dependent pathways in sheep pulmonary artery. | Vascular pharmacology 20120101 |
| 20-HETE-producing enzymes are up-regulated in human cancers. | Cancer genomics & proteomics 20120101 |
| A novel treatment strategy for sepsis and septic shock based on the interactions between prostanoids, nitric oxide, and 20-hydroxyeicosatetraenoic acid. | Anti-inflammatory & anti-allergy agents in medicinal chemistry 20120101 |
| Cytochrome P450 metabolites of arachidonic acid are elevated in stroke patients compared with healthy controls. | Clinical science (London, England : 1979) 20111201 |
| The role of 20-HETE in androgen-mediated hypertension. | Prostaglandins & other lipid mediators 20111101 |
| 11,12-EET increases porto-sinusoidal resistance and may play a role in endothelial dysfunction of portal hypertension. | Prostaglandins & other lipid mediators 20111101 |
| Isolated human and rat cerebral arteries constrict to increases in flow: role of 20-HETE and TP receptors. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20111001 |
| Piroxicam reverses endotoxin-induced hypotension in rats: contribution of vasoactive eicosanoids and nitric oxide. | Basic & clinical pharmacology & toxicology 20110901 |
| The cytochrome P450 4A/F-20-hydroxyeicosatetraenoic acid system: a regulator of endothelial precursor cells derived from human umbilical cord blood. | The Journal of pharmacology and experimental therapeutics 20110801 |
| Epoxyeicosatrienoic acid-dependent cerebral vasodilation evoked by metabotropic glutamate receptor activation in vivo. | American journal of physiology. Heart and circulatory physiology 20110801 |
| 20-hydroxyeicosatetraenoic acid, endothelial dysfunction and hypertension. | Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina 20110801 |
| Cerebrospinal fluid 20-HETE is associated with delayed cerebral ischemia and poor outcomes after aneurysmal subarachnoid hemorrhage. | Stroke 20110701 |
| Inhibition of 20-HETE attenuates diabetes-induced decreases in retinal hemodynamics. | Experimental eye research 20110701 |
| 20-Hydroxyeicosatetraenoic acid inhibits ATP-induced COX-2 expression via peroxisome proliferator activator receptor-α in vascular smooth muscle cells. | British journal of pharmacology 20110601 |
| Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20110601 |
| Postmenopausal hypertension: role of 20-HETE. | American journal of physiology. Regulatory, integrative and comparative physiology 20110601 |
| Pressure-induced myogenic tone and role of 20-HETE in mediating autoregulation of cerebral blood flow. | American journal of physiology. Heart and circulatory physiology 20110501 |
| Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6. | Drug metabolism and disposition: the biological fate of chemicals 20110501 |
| Chronic activation of AMP-activated protein kinase prevents 20-hydroxyeicosatetraenoic acid-induced endothelial dysfunction. | Clinical and experimental pharmacology & physiology 20110501 |
| Arachidonic acid epoxygenase and 12(S)-lipoxygenase: evidence of their concerted involvement in ductus arteriosus constriction to oxygen. | Canadian journal of physiology and pharmacology 20110501 |
| Study on the association between environmental cadmium exposure, cytochrome P450-mediated 20-HETE, heme-oxygenase-1 polymorphism and hypertension in Thai population residing in a malaria endemic areas with cadmium pollution. | Environmental toxicology and pharmacology 20110501 |
| Interaction of nitric oxide and the cytochrome P-450 system on blood pressure and renal function in the rat: dependence on sodium intake. | Acta physiologica (Oxford, England) 20110401 |
| 20-Hydroxyeicosatetraenoic acid synthesis is increased in human neutrophils and platelets by angiotensin II and endothelin-1. | American journal of physiology. Heart and circulatory physiology 20110401 |
| Androgen-dependent hypertension is mediated by 20-hydroxy-5,8,11,14-eicosatetraenoic acid-induced vascular dysfunction: role of inhibitor of kappaB Kinase. | Hypertension (Dallas, Tex. : 1979) 20110401 |
| Peripheral and central augmentation indexes in relation to the CYP4F2 polymorphisms in Chinese. | Journal of hypertension 20110301 |
| 20-Hydroxyeicosatetraenoic acid induces apoptosis in neonatal rat cardiomyocytes through mitochondrial-dependent pathways. | Journal of cardiovascular pharmacology 20110301 |
| Cytochrome P450 eicosanoids and cerebral vascular function. | Expert reviews in molecular medicine 20110301 |
| Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury. | Kidney international 20110101 |
| 20-HETE in acute kidney injury. | Kidney international 20110101 |
| Role of 20-hydroxyeicosatetraenoic acid in mediating hypertension in response to chronic renal medullary endothelin type B receptor blockade. | PloS one 20110101 |
| Lipoxygenase-derived hydroxyeicosatetraenoic acids--novel perioperative markers of early post-transplant allograft function? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101201 |
| 2,3',4,5'-Tetramethoxystilbene prevents deoxycorticosterone-salt-induced hypertension: contribution of cytochrome P-450 1B1. | American journal of physiology. Heart and circulatory physiology 20101201 |
| The effects of a lupin-enriched diet on oxidative stress and factors influencing vascular function in overweight subjects. | Antioxidants & redox signaling 20101115 |
| The inhibitor of 20-HETE synthesis, TS-011, improves cerebral microcirculatory autoregulation impaired by middle cerebral artery occlusion in mice. | British journal of pharmacology 20101101 |
| 20-hydroxyeicosatetraenoic acid and angiotensin: a positive feedback system to cause hypertension. | Hypertension (Dallas, Tex. : 1979) 20101101 |
| CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent. | Hypertension (Dallas, Tex. : 1979) 20101101 |
| Renal function and vasomotor activity in mice lacking the Cyp4a14 gene. | Experimental biology and medicine (Maywood, N.J.) 20101101 |
| 20-HETE increases NADPH oxidase-derived ROS production and stimulates the L-type Ca2+ channel via a PKC-dependent mechanism in cardiomyocytes. | American journal of physiology. Heart and circulatory physiology 20101001 |
| 20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension. | Journal of cardiovascular pharmacology 20101001 |
| Modulation by cytochrome P450-4A ω-hydroxylase enzymes of adrenergic vasoconstriction and response to reduced PO₂ in mesenteric resistance arteries of Dahl salt-sensitive rats. | Microcirculation (New York, N.Y. : 1994) 20101001 |
| Increased cytochrome P4502E1 expression and altered hydroxyeicosatetraenoic acid formation mediate diabetic vascular dysfunction: rescue by guanylyl-cyclase activation. | Diabetes 20100801 |
| Genetic polymorphism of CYP2U1, a cytochrome P450 involved in fatty acids hydroxylation. | Prostaglandins, leukotrienes, and essential fatty acids 20100801 |
| Endothelin-1 induced vascular smooth muscle cell proliferation is mediated by cytochrome p-450 arachidonic acid metabolites. | Bosnian journal of basic medical sciences 20100801 |
| A synthetic analogue of 20-HETE, 5,14-HEDGE, reverses endotoxin-induced hypotension via increased 20-HETE levels associated with decreased iNOS protein expression and vasodilator prostanoid production in rats. | Basic & clinical pharmacology & toxicology 20100501 |
| Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation. | Pharmacological research 20100501 |
| 20-HETE-induced nitric oxide production in pulmonary artery endothelial cells is mediated by NADPH oxidase, H2O2, and PI3-kinase/Akt. | American journal of physiology. Lung cellular and molecular physiology 20100401 |
| Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats. | Clinical science (London, England : 1979) 20100223 |
| Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats. | Toxicology and applied pharmacology 20100101 |
| 20-hydroxy-5,8,11,14-eicosatetraenoic acid mediates endothelial dysfunction via IkappaB kinase-dependent endothelial nitric-oxide synthase uncoupling. | The Journal of pharmacology and experimental therapeutics 20100101 |
| 20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice. | PloS one 20100101 |
| Cytochrome P450-dependent metabolism of omega-6 and omega-3 long-chain polyunsaturated fatty acids. | Pharmacological reports : PR 20100101 |
| Role of 20-hydroxyeicosatetraenoic and epoxyeicosatrienoic acids in the regulation of vascular function in a model of hypertension and endothelial dysfunction. | Pharmacology 20100101 |
| CYP450 4A inhibition attenuates O2 induced arteriolar constriction in chronic but not acute Goldblatt hypertension. | Microvascular research 20091201 |
| Inhibition of the adenosine2A receptor-epoxyeicosatrienoic acid pathway renders Dahl salt-resistant rats hypertensive. | Hypertension (Dallas, Tex. : 1979) 20091201 |
| Rapid, simultaneous quantitation of mono and dioxygenated metabolites of arachidonic acid in human CSF and rat brain. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091201 |
| The role of 20-hydroxyeicosatetraenoic acid in cerebral arteriolar constriction and the inhibitory effect of propofol. | Anesthesia and analgesia 20091201 |
| Inhibition of 20-hydroxyeicosatetraenoic acid synthesis using specific plant lignans: in vitro and human studies. | Hypertension (Dallas, Tex. : 1979) 20091101 |
| CYP-omega-hydroxylation-dependent metabolites of arachidonic acid inhibit the basolateral 10 pS chloride channel in the rat thick ascending limb. | Kidney international 20091001 |
| Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE. | American journal of physiology. Renal physiology 20091001 |
| Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic acid production and arterial blood pressure. | Kidney international 20091001 |
| Down-regulation of 20-HETE synthesis and signaling inhibits renal adenocarcinoma cell proliferation and tumor growth. | Anticancer research 20091001 |
| 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism. | American journal of physiology. Renal physiology 20090901 |
| [Chemical-mechanical synergism for cardiovascular TRPC6 channel activation via PLC/diacylglycerol and PLA2/omega-hydroxylase/20-HETE pathways]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20090901 |
| The role of 20-hydroxyeicosatetraenoic acid in adrenocorticotrophic hormone and dexamethasone-induced hypertension. | Journal of hypertension 20090801 |
| 20-HETE can act as a nonhypoxic regulator of HIF-1alpha in human microvascular endothelial cells. | American journal of physiology. Heart and circulatory physiology 20090801 |
| Synergistic activation of vascular TRPC6 channel by receptor and mechanical stimulation via phospholipase C/diacylglycerol and phospholipase A2/omega-hydroxylase/20-HETE pathways. | Circulation research 20090619 |
| Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic acid production and arterial blood pressure. | Kidney international 20090601 |
| Arachidonic acid cytochrome P450 4F2 in hypertension: what can we learn from a transgenic mouse model?? | Kidney international 20090601 |
| Is it possible to predict the early post-transplant allograft function using 20-HETE measurements? A preliminary report. | Transplant international : official journal of the European Society for Organ Transplantation 20090501 |
| Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases. | Diabetes 20090501 |
| Modulation of vascular O2 responses by cytochrome 450-4A omega-hydroxylase metabolites in Dahl salt-sensitive rats. | Microcirculation (New York, N.Y. : 1994) 20090501 |
| Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients. | Diabetes care 20090501 |
| Endothelin rather than 20-HETE contributes to loss of pial arteriolar dilation during focal cerebral ischemia with and without polymeric hemoglobin transfusion. | American journal of physiology. Regulatory, integrative and comparative physiology 20090501 |
| Myoendothelial coupling in the mesenteric arterial bed; segmental differences and interplay between nitric oxide and endothelin-1. | British journal of pharmacology 20090401 |
| Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury. | Kidney international 20090301 |
| Effect of 20-HETE inhibition on infarct volume and cerebral blood flow after transient middle cerebral artery occlusion. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090301 |
| High-salt diet enhances mouse aortic relaxation through adenosine A2A receptor via CYP epoxygenases. | American journal of physiology. Regulatory, integrative and comparative physiology 20090301 |
| Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD. | American journal of physiology. Renal physiology 20090301 |
| Glomerular 20-HETE, EETs, and TGF-beta1 in diabetic nephropathy. | American journal of physiology. Renal physiology 20090301 |
| 20-HETE increases survival and decreases apoptosis in pulmonary arteries and pulmonary artery endothelial cells. | American journal of physiology. Heart and circulatory physiology 20090301 |
| 20-HETE and F2-isoprostanes in the metabolic syndrome: the effect of weight reduction. | Free radical biology & medicine 20090115 |
| Microsomal omega-hydroxylated metabolites of N-arachidonoyl dopamine are active at recombinant human TRPV1 receptors. | Prostaglandins & other lipid mediators 20090101 |
| Role of 20-hydroxyeicosatetraenoic acid in altering vascular reactivity in diabetes. | Autonomic & autacoid pharmacology 20090101 |
| Cytochrome P450 metabolites of arachidonic acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury. | Autonomic & autacoid pharmacology 20090101 |
| Transfer of the CYP4A region of chromosome 5 from Lewis to Dahl S rats attenuates renal injury. | American journal of physiology. Renal physiology 20081201 |
| Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats. | American journal of physiology. Heart and circulatory physiology 20081201 |
| Cytochrome P-450 metabolites in renal circulation and excretion--interaction with the nitric oxide (NO) system. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20081201 |
| Intravenous formulation of N-hydroxy-N'-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for inhibition of rat brain 20-hydroxyeicosatetraenoic acid formation. | Drug metabolism and disposition: the biological fate of chemicals 20081101 |
| Cytochrome P450 omega-hydroxylase inhibition reduces cardiomyocyte apoptosis via activation of ERK1/2 signaling in rat myocardial ischemia-reperfusion. | European journal of pharmacology 20081031 |
| Insensitivity of cerebral oxygen transport to oxygen affinity of hemoglobin-based oxygen carriers. | Biochimica et biophysica acta 20081001 |
| CYP4F3B is induced by PGA1 in human liver cells: a regulation of the 20-HETE synthesis. | Journal of lipid research 20081001 |
| Expression of CYP4A1 in U251 human glioma cell induces hyperproliferative phenotype in vitro and rapidly growing tumors in vivo. | The Journal of pharmacology and experimental therapeutics 20081001 |
| 20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease. | Journal of the American Society of Nephrology : JASN 20081001 |
| Colfibrate attenuates blood pressure and sodium retention in DOCA-salt hypertension. | Kidney international 20081001 |
| A 20-hydroxyeicosatetraenoic acid agonist, N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine, opposes the fall in blood pressure and vascular reactivity in endotoxin-treated rats. | Shock (Augusta, Ga.) 20080901 |
| Interaction of nitric oxide, 20-HETE, and EETs during functional hyperemia in whisker barrel cortex. | American journal of physiology. Heart and circulatory physiology 20080801 |
| The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure. | Hypertension (Dallas, Tex. : 1979) 20080801 |
| Renoprotective effects of soy protein hydrolysates in N(omega)-nitro-L-arginine methyl ester hydrochloride-induced hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20080701 |
| 20-Hydroxyeicosatetraenoic acid inhibits the apoptotic responses in pulmonary artery smooth muscle cells. | European journal of pharmacology 20080624 |
| 20-HETE increases renal sympathetic nerve activity via activation of chemically and mechanically sensitive muscle afferents. | The Journal of physiology 20080515 |
| Arachidonic acid metabolism in glucocorticoid-induced hypertension. | Clinical and experimental pharmacology & physiology 20080501 |
| 20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells. | American journal of physiology. Lung cellular and molecular physiology 20080501 |
| Deficient renal 20-HETE release in the diabetic rat is not the result of oxidative stress. | American journal of physiology. Heart and circulatory physiology 20080501 |
| Altered release of cytochrome p450 metabolites of arachidonic acid in renovascular disease. | Hypertension (Dallas, Tex. : 1979) 20080501 |
| A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure. | Hypertension (Dallas, Tex. : 1979) 20080501 |
| Association of a functional cytochrome P450 4F2 haplotype with urinary 20-HETE and hypertension. | Journal of the American Society of Nephrology : JASN 20080401 |
| Haplotype-based case study of human CYP4A11 gene and cerebral infarction in Japanese subject. | Endocrine 20080401 |
| 20-HETE-mediated cytotoxicity and apoptosis in ischemic kidney epithelial cells. | American journal of physiology. Renal physiology 20080301 |
| Effects of omega-hydroxylase product on distal human pulmonary arteries. | American journal of physiology. Heart and circulatory physiology 20080301 |
| The T8590C polymorphism of CYP4A11 and 20-hydroxyeicosatetraenoic acid in essential hypertension. | Hypertension (Dallas, Tex. : 1979) 20080301 |
| Aging increases cytochrome P450 4A modulation of alpha1-adrenergic vasoconstriction in mesenteric arteries. | Journal of cardiovascular pharmacology 20080301 |
| Endothelial dysfunction and improvement of the angiotensin II-reactivity in hypercholesterolemic rabbits: role of cyclooxygenase metabolites. | European journal of pharmacology 20080202 |
| 20-hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling. | American journal of physiology. Heart and circulatory physiology 20080201 |
| Role of 20-HETE in the hypoxia-induced activation of Ca2+-activated K+ channel currents in rat cerebral arterial muscle cells. | American journal of physiology. Heart and circulatory physiology 20080101 |
| 20-HETE inhibits the proliferation of vascular smooth muscle cells via transforming growth factor-beta. | Journal of lipid research 20080101 |
| 20-Hydroxyeicosatetraenoic acid stimulates nuclear factor-kappaB activation and the production of inflammatory cytokines in human endothelial cells. | The Journal of pharmacology and experimental therapeutics 20080101 |
| Cerebral blood flow changes in acute subarachnoid hemorrhage. | Frontiers in bioscience : a journal and virtual library 20080101 |
| Renal vascular cytochrome P450-derived eicosanoids in androgen-induced hypertension. | Pharmacological reports : PR 20080101 |
| Continuous inhibition of 20-HETE synthesis by TS-011 improves neurological and functional outcomes after transient focal cerebral ischemia in rats. | Neuroscience research 20071201 |
| Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine. | Drug metabolism and disposition: the biological fate of chemicals 20071101 |
| Functional effects of 20-HETE on human bronchi: hyperpolarization and relaxation due to BKCa channel activation. | American journal of physiology. Lung cellular and molecular physiology 20071001 |
| Regulation of ion transport and blood pressure by cytochrome p450 monooxygenases. | Current opinion in nephrology and hypertension 20070901 |
| Role of endogenous CYP450 metabolites of arachidonic acid in maintaining the glomerular protein permeability barrier. | American journal of physiology. Renal physiology 20070801 |
| Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha. | Drug metabolism and disposition: the biological fate of chemicals 20070701 |
| Does 20-hydroxyeicosatetraenoic acid contribute to sex differences in cardiovascular risk by increasing oxidative stress? | Hypertension (Dallas, Tex. : 1979) 20070701 |
| Vascular cytochrome P450 4A expression and 20-hydroxyeicosatetraenoic acid synthesis contribute to endothelial dysfunction in androgen-induced hypertension. | Hypertension (Dallas, Tex. : 1979) 20070701 |
| Functional polymorphism in human CYP4F2 decreases 20-HETE production. | Physiological genomics 20070619 |
| Effects of 20-HETE on Na+ transport and Na+ -K+ -ATPase activity in the thick ascending loop of Henle. | American journal of physiology. Regulatory, integrative and comparative physiology 20070601 |
| A reduction in alcohol consumption is associated with reduced plasma F2-isoprostanes and urinary 20-HETE excretion in men. | Free radical biology & medicine 20070601 |
| Role of 20-HETE in D1/D2 dopamine receptor synergism resulting in the inhibition of Na+-K+-ATPase activity in the proximal tubule. | American journal of physiology. Renal physiology 20070501 |
| Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. | The Journal of pharmacology and experimental therapeutics 20070501 |
| Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation. | The Journal of pharmacology and experimental therapeutics 20070401 |
| [Roles of 20-HETE on physiologic and pathologic regulation in organism]. | Sheng li ke xue jin zhan [Progress in physiology] 20070401 |
| High dietary salt reduces the contribution of 20-HETE to arteriolar oxygen responsiveness in skeletal muscle. | American journal of physiology. Heart and circulatory physiology 20070301 |
| Elevations in renal interstitial hydrostatic pressure and 20-hydroxyeicosatetraenoic acid contribute to pressure natriuresis. | Hypertension (Dallas, Tex. : 1979) 20070301 |
| 20-carboxy-arachidonic acid is a dual activator of peroxisome proliferator-activated receptors alpha and gamma. | Prostaglandins & other lipid mediators 20070101 |
| 20-Hydroxyeicosatetraenoic acid (20-HETE) stimulates migration of vascular smooth muscle cells. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101 |
| Effects of chronic cytochrome P-450 inhibition on the course of hypertension and end-organ damage in Ren-2 transgenic rats. | Vascular pharmacology 20070101 |
| The roles of intrarenal 20-hydroxyeicosatetraenoic and epoxyeicosatrienoic acids in the regulation of renal function in hypertensive Ren-2 transgenic rats. | Kidney & blood pressure research 20070101 |
| Role of cytochrome P450 metabolites of arachidonic acid in regulation of corporal smooth muscle tone in diabetic and older rats. | Vascular pharmacology 20070101 |
| Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20061201 |
| 20-Hydroxyeicosatetraenoic acid is not associated with circulating insulin in lean to overweight humans. | Diabetes research and clinical practice 20061101 |
| 20-Hydroxyeicosatetraenoic acid is a potent dilator of mouse basilar artery: role of cyclooxygenase. | American journal of physiology. Heart and circulatory physiology 20061101 |
| Inability to upregulate cytochrome P450 4A and 2C causes salt sensitivity in young Sprague-Dawley rats. | American journal of hypertension 20061101 |
| 20-HETE and salt-sensitivity of blood pressure a novel emerging concept. | American journal of hypertension 20061101 |
| Cytochrome P-450 monooxygenases in control of renal haemodynamics and arterial pressure in anaesthetized rats. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061101 |
| Increased renal vascular reactivity to ANG II after unilateral nephrectomy in the rat involves 20-HETE. | American journal of physiology. Regulatory, integrative and comparative physiology 20061001 |
| Editorial: experimental subarachnoid hemorrhage second issue: cerebral vasospasm. | Neurological research 20061001 |
| Evidence that 20-HETE contributes to the development of acute and delayed cerebral vasospasm. | Neurological research 20061001 |
| Mechanisms of activation of eNOS by 20-HETE and VEGF in bovine pulmonary artery endothelial cells. | American journal of physiology. Lung cellular and molecular physiology 20060901 |
| VEGF-induced relaxation of pulmonary arteries is mediated by endothelial cytochrome P-450 hydroxylase. | American journal of physiology. Lung cellular and molecular physiology 20060901 |
| Oxygenation of omega-3 fatty acids by human cytochrome P450 4F3B: effect on 20-hydroxyeicosatetraenoic acid production. | Prostaglandins, leukotrienes, and essential fatty acids 20060901 |
| Nitric oxide/cytochrome P450 interactions in cyclosporin A-induced effects in the rat. | Journal of hypertension 20060901 |
| Epoxyeicosatrienoic acids in cardioprotection: ischemic versus reperfusion injury. | American journal of physiology. Heart and circulatory physiology 20060801 |
| Characterization of blood pressure and renal function in chromosome 5 congenic strains of Dahl S rats. | American journal of physiology. Renal physiology 20060601 |
| Effect of a new inhibitor of the synthesis of 20-HETE on cerebral ischemia reperfusion injury. | Stroke 20060501 |
| Endothelial dysfunction and hypertension in rats transduced with CYP4A2 adenovirus. | Circulation research 20060414 |
| Endothelial dysfunction and hypertension in rats transduced with CYP4A2 adenovirus. | Circulation research 20060414 |
| Induction of renal 20-hydroxyeicosatetraenoic acid by clofibrate attenuates high-fat diet-induced hypertension in rats. | The Journal of pharmacology and experimental therapeutics 20060401 |
| Glial cells dilate and constrict blood vessels: a mechanism of neurovascular coupling. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315 |
| Effect of alcohol on cytochrome p450 arachidonic acid metabolism and blood pressure in rats and its modulation by red wine polyphenolics. | Clinical and experimental pharmacology & physiology 20060301 |
| Expression of cytochrome P-450 4 enzymes in the kidney and liver: regulation by PPAR and species-difference between rat and human. | Molecular and cellular biochemistry 20060301 |
| Elevated 12- and 20-hydroxyeicosatetraenoic acid in urine of patients with prostatic diseases. | Cancer letters 20060227 |
| Effects of selective inhibition of cytochrome P-450 omega-hydroxylases and ischemic preconditioning in myocardial protection. | American journal of physiology. Heart and circulatory physiology 20060201 |
| Hemoglobin, NO, and 20-HETE interactions in mediating cerebral vasoconstriction following SAH. | American journal of physiology. Regulatory, integrative and comparative physiology 20060101 |
| Role of 20-HETE in the pial arteriolar constrictor response to decreased hematocrit after exchange transfusion of cell-free polymeric hemoglobin. | Journal of applied physiology (Bethesda, Md. : 1985) 20060101 |
| Reversal of delayed vasospasm by TS-011 in the dual hemorrhage dog model of subarachnoid hemorrhage. | AJNR. American journal of neuroradiology 20060101 |
| Cytochrome P-450-dependent metabolism of arachidonic acid in the kidney of rats with diabetes insipidus. | American journal of physiology. Renal physiology 20051201 |
| Constrictor-induced translocation of NFAT3 in human and rat pulmonary artery smooth muscle. | American journal of physiology. Lung cellular and molecular physiology 20051201 |
| Reversal of delayed vasospasm by an inhibitor of the synthesis of 20-HETE. | American journal of physiology. Heart and circulatory physiology 20051101 |
| Renal 20-HETE inhibition attenuates changes in renal hemodynamics induced by L-NAME treatment in pregnant rats. | American journal of physiology. Renal physiology 20051101 |
| Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine], a selective inhibitor of CYP4A. | The Journal of pharmacology and experimental therapeutics 20051101 |
| Glomerular cytochrome P-450 and cyclooxygenase metabolites regulate efferent arteriole resistance. | Hypertension (Dallas, Tex. : 1979) 20051101 |
| Cytochrome P450 and arachidonic acid metabolites: role in myocardial ischemia/reperfusion injury revisited. | Cardiovascular research 20051001 |
| Omega-oxidation of 20-hydroxyeicosatetraenoic acid (20-HETE) in cerebral microvascular smooth muscle and endothelium by alcohol dehydrogenase 4. | The Journal of biological chemistry 20050930 |
| Inhibition of Ca2+/calmodulin-dependent protein kinase II, RAS-GTPase and 20-hydroxyeicosatetraenoic acid attenuates the development of diabetes-induced vascular dysfunction in the rat carotid artery. | Pharmacological research 20050901 |
| Contribution of 20-HETE to augmented myogenic constriction in coronary arteries of endothelial NO synthase knockout mice. | Hypertension (Dallas, Tex. : 1979) 20050901 |
| Cytochrome P450 4A isoform inhibitory profile of N-hydroxy-N'-(4-butyl-2-methylphenyl)-formamidine (HET0016), a selective inhibitor of 20-HETE synthesis. | Biological & pharmaceutical bulletin 20050901 |
| Taking the 20-HETE out of the cardiovascular system: the potential of 20-HETE synthesis inhibitors. | Current opinion in investigational drugs (London, England : 2000) 20050901 |
| Long-term modifications of blood pressure in normotensive and spontaneously hypertensive rats by gene delivery of rAAV-mediated cytochrome P450 arachidonic acid hydroxylase. | Cell research 20050901 |
| Exaggerated response to adenosine in kidneys from high salt-fed rats: role of epoxyeicosatrienoic acids. | American journal of physiology. Renal physiology 20050801 |
| Inhibition of 20-HETE abolishes the myogenic response during NOS antagonism in the ovine fetal pulmonary circulation. | American journal of physiology. Lung cellular and molecular physiology 20050801 |
| Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular system. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20050801 |
| Evaluation of cytochrome P450 4 family as mediator of phospholipase D activation in aortic vascular smooth muscle cells. | Life sciences 20050715 |
| Beneficial effects of a new 20-hydroxyeicosatetraenoic acid synthesis inhibitor, TS-011 [N-(3-chloro-4-morpholin-4-yl) phenyl-N'-hydroxyimido formamide], on hemorrhagic and ischemic stroke. | The Journal of pharmacology and experimental therapeutics 20050701 |
| Endothelial dysfunction: its role in hypertensive coronary disease. | Current opinion in cardiology 20050701 |
| Identification and quantification of the hydroxyeicosatetraenoic acids, 20-HETE and 12-HETE, in the cerebrospinal fluid after subarachnoid hemorrhage. | Journal of neuroscience methods 20050615 |
| Differential effects of 20-hydroxyeicosatetraenoic acid on intrarenal blood flow in the rat. | The Journal of pharmacology and experimental therapeutics 20050601 |
| Parathormone sensitivity and responses to protein kinases in subclones of opossum kidney cells. | Pediatric nephrology (Berlin, Germany) 20050601 |
| Contribution of arachidonic acid metabolites derived via cytochrome P4504A to angiotensin II-induced neointimal growth. | Hypertension (Dallas, Tex. : 1979) 20050601 |
| Urinary 20-hydroxyeicosatetraenoic acid excretion is associated with oxidative stress in hypertensive subjects. | Free radical biology & medicine 20050415 |
| Effects of high-salt diet on CYP450-4A omega-hydroxylase expression and active tone in mesenteric resistance arteries. | American journal of physiology. Heart and circulatory physiology 20050401 |
| Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension. | Hypertension (Dallas, Tex. : 1979) 20050401 |
| Fenofibrate prevents the development of angiotensin II-dependent hypertension in mice. | Hypertension (Dallas, Tex. : 1979) 20050401 |
| Transforming growth factor-beta, 20-HETE interaction, and glomerular injury in Dahl salt-sensitive rats. | Hypertension (Dallas, Tex. : 1979) 20050401 |
| 20-HETE-mediated vasoconstriction by hemoglobin-O2 carrier in Sprague-Dawley but not Wistar rats. | Journal of applied physiology (Bethesda, Md. : 1985) 20050301 |
| Capsazepine, a vanilloid antagonist, abolishes tonic responses induced by 20-HETE on guinea pig airway smooth muscle. | American journal of physiology. Lung cellular and molecular physiology 20050301 |
| The synthesis of 20-HETE in small porcine coronary arteries antagonizes EDHF-mediated relaxation. | Cardiovascular research 20050201 |
| P450 in the angiogenesis affair: the unusual suspect. | The American journal of pathology 20050201 |
| Inhibitors of cytochrome P450 4A suppress angiogenic responses. | The American journal of pathology 20050201 |
| Pathophysiological role of 20-HETE a cytochrome P450 metabolite of arachidonic acid. | Journal of pharmacological sciences 20050201 |
| Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension. | Circulation 20050104 |
| Cytochrome P-450 under pressure: more evidence for a link between 20-hydroxyeicosatetraenoic acid and hypertension. | Circulation 20050104 |
| Decreased levels of cytochrome P450 2E1-derived eicosanoids sensitize renal arteries to constrictor agonists in spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20050101 |
| Protective effect of 20-hydroxyeicosatetraenoic acid (20-HETE) on glomerular protein permeability barrier. | Kidney international 20050101 |
| Increased excretion of urinary 20-HETE in rats with cyclosporine-induced nephrotoxicity. | Journal of pharmacological sciences 20050101 |
| Regulation and inhibition of arachidonic acid omega-hydroxylases and 20-HETE formation. | Annual review of pharmacology and toxicology 20050101 |
| Transfection and functional expression of CYP4A1 and CYP4A2 using bicistronic vectors in vascular cells and tissues. | The Journal of pharmacology and experimental therapeutics 20041201 |
| P2X receptor-stimulated calcium responses in preglomerular vascular smooth muscle cells involves 20-hydroxyeicosatetraenoic acid. | The Journal of pharmacology and experimental therapeutics 20041201 |
| Pyrazole derivatives as new potent and selective 20-hydroxy-5,8,11,14-eicosatetraenoic acid synthase inhibitors. | Bioorganic & medicinal chemistry 20041201 |
| Cytochrome P450 omega-hydroxylase inhibition reduces infarct size during reperfusion via the sarcolemmal KATP channel. | Journal of molecular and cellular cardiology 20041201 |
| Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction. | Circulation research 20041112 |
| Dietary K intake regulates the response of apical K channels to adenosine in the thick ascending limb. | American journal of physiology. Renal physiology 20041101 |
| Design and synthesis of 1-(4-benzoylphenyl)imidazole derivatives as new potent 20-HETE synthase inhibitors. | Bioorganic & medicinal chemistry letters 20041101 |
| Inhibition of cytochrome P450omega-hydroxylase: a novel endogenous cardioprotective pathway. | Circulation research 20041015 |
| Changes in renal haemodynamics induced by indomethacin in the rat involve cytochrome P450 arachidonic acid-dependent epoxygenases. | Clinical and experimental pharmacology & physiology 20041001 |
| [Role of androgens in the renal production of 20-hydroxyeicosatetraenoic acid in spontaneously hypertensive rats]. | Nihon Jinzo Gakkai shi 20041001 |
| Neurobiology: feeding the brain. | Nature 20040909 |
| Calcium transients in astrocyte endfeet cause cerebrovascular constrictions. | Nature 20040909 |
| Transfection of CYP4A1 cDNA decreases diameter and increases responsiveness of gracilis muscle arterioles to constrictor stimuli. | American journal of physiology. Heart and circulatory physiology 20040901 |
| Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases. | Journal of lipid research 20040901 |
| 20-hydroxyeicosatetraenoic acid is a vasoconstrictor in the newborn piglet pulmonary microcirculation. | American journal of physiology. Lung cellular and molecular physiology 20040801 |
| Vascular CO counterbalances the sensitizing influence of 20-HETE on agonist-induced vasoconstriction. | Hypertension (Dallas, Tex. : 1979) 20040801 |
| Activation of Na+-independent Mg2+ efflux by 20-hydroxyeicosatetraenoic acid in rat renal epithelial cells. | The Japanese journal of physiology 20040801 |
| Urinary 20-hydroxyeicosatetraenoic acid is associated with endothelial dysfunction in humans. | Circulation 20040727 |
| Inhibition of the formation of EETs and 20-HETE with 1-aminobenzotriazole attenuates pressure natriuresis. | American journal of physiology. Regulatory, integrative and comparative physiology 20040701 |
| 20-HETE or EETs: which arachidonic acid metabolite regulates proximal tubule transporters and contributes to pressure natriuresis? | American journal of physiology. Regulatory, integrative and comparative physiology 20040701 |
| The effect of isoniazid on CYP2E1- and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney. | Drug metabolism and disposition: the biological fate of chemicals 20040701 |
| Cytochrome P-450 metabolites in endothelin-stimulated cardiac hormone secretion. | American journal of physiology. Regulatory, integrative and comparative physiology 20040501 |
| Elevated BSC-1 and ROMK expression in Dahl salt-sensitive rat kidneys. | Hypertension (Dallas, Tex. : 1979) 20040401 |
| Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes. | The Journal of pharmacology and experimental therapeutics 20040301 |
| Role of 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids in hypertension. | Current opinion in nephrology and hypertension 20040301 |
| Effects of a 20-HETE antagonist and agonists on cerebral vascular tone. | European journal of pharmacology 20040223 |
| CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids. | The Journal of biological chemistry 20040220 |
| Smooth muscle--specific expression of CYP4A1 induces endothelial sprouting in renal arterial microvessels. | Circulation research 20040206 |
| 20-HETE and circulating insulin in essential hypertension with obesity. | Hypertension (Dallas, Tex. : 1979) 20040201 |
| 20-hydroxyeicosatetraenoic acid (20-HETE) metabolism in coronary endothelial cells. | The Journal of biological chemistry 20040123 |
| Imidazole derivatives as new potent and selective 20-HETE synthase inhibitors. | Bioorganic & medicinal chemistry letters 20040119 |
| Measurement of 20-hydroxyeicosatetraenoic acid in human urine by gas chromatography-mass spectrometry. | Clinical chemistry 20040101 |
| Renal COX-2, cytokines and 20-HETE: tubular and vascular mechanisms. | Current pharmaceutical design 20040101 |
| Evaluation of cytochrome P450-4A omega-hydroxylase and 20-hydroxyeicosatetraenoic acid as an O2 sensing mechanism in the microcirculation. | Methods in enzymology 20040101 |
| Regulation of cytochrome P-450 4A activity by peroxisome proliferator-activated receptors in the rat kidney. | Hypertension research : official journal of the Japanese Society of Hypertension 20031101 |
| Asian Federation of Medicinal Chemistry (AFMC) - Fifth International Medicinal Chemistry Symposium. 14-17 October 2003, Kyoto, Japan. | IDrugs : the investigational drugs journal 20031101 |
| Fatty acid-binding proteins inhibit hydration of epoxyeicosatrienoic acids by soluble epoxide hydrolase. | Biochemistry 20031014 |
| Inhibitors of 20-HETE formation promote salt-sensitive hypertension in rats. | Hypertension (Dallas, Tex. : 1979) 20031001 |
| Role of COX-2 in the enhanced vasoconstrictor effect of arachidonic acid in the diabetic rat kidney. | Hypertension (Dallas, Tex. : 1979) 20031001 |
| Inhibitors of 20-hydroxyeicosatetraenoic acid reduce renal vasoconstrictor responsiveness. | The Journal of pharmacology and experimental therapeutics 20031001 |
| Determination of 20-hydroxyeicosatetraenoic acid in microsomal incubates using high-performance liquid chromatography-mass spectrometry (HPLC-MS). | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030905 |
| 20-HETE inotropic effects involve the activation of a nonselective cationic current in airway smooth muscle. | American journal of physiology. Lung cellular and molecular physiology 20030901 |
| 20-hydroxyeicosatetraenoic acid (20-HETE) activates mouse TRPC6 channels expressed in HEK293 cells. | The Journal of biological chemistry 20030822 |
| Regulation of renal CYP4A expression and 20-HETE synthesis by nitric oxide in pregnant rats. | American journal of physiology. Renal physiology 20030801 |
| Dopamine D1 receptor-dependent inhibition of NaCl transport in the rat thick ascending limb: mechanism of action. | European journal of pharmacology 20030725 |
| 20-hydroxyeicosatetraenoic acid (20-HETE): structural determinants for renal vasoconstriction. | Bioorganic & medicinal chemistry 20030703 |
| CYP4A metabolites of arachidonic acid and VEGF are mediators of skeletal muscle angiogenesis. | American journal of physiology. Heart and circulatory physiology 20030501 |
| Contribution of 5-hydroxytryptamine1B receptors and 20-hydroxyeiscosatetraenoic acid to fall in cerebral blood flow after subarachnoid hemorrhage. | Stroke 20030501 |
| Functional expression of human heme oxygenase-1 gene in renal structure of spontaneously hypertensive rats. | Experimental biology and medicine (Maywood, N.J.) 20030501 |
| Androgen-mediated induction of the kidney arachidonate hydroxylases is associated with the development of hypertension. | American journal of physiology. Regulatory, integrative and comparative physiology 20030401 |
| Cyclooxygenase and cytochrome P-450 pathways induced by fetal calf serum regulate wound closure in 3T6 fibroblast cultures through the effect of prostaglandin E2 and 12 and 20 hydroxyeicosatetraenoic acids. | Journal of cellular physiology 20030401 |
| Androgen-induced activation of 20-HETE production may contribute to gender differences in blood pressure regulation. | American journal of physiology. Regulatory, integrative and comparative physiology 20030401 |
| Renal arterial 20-hydroxyeicosatetraenoic acid levels: regulation by cyclooxygenase. | American journal of physiology. Renal physiology 20030301 |
| Contributions of 20-HETE to the antihypertensive effects of Tempol in Dahl salt-sensitive rats. | Hypertension (Dallas, Tex. : 1979) 20030301 |
| 20-HETE and furosemide-induced natriuresis in salt-sensitive essential hypertension. | Hypertension (Dallas, Tex. : 1979) 20030301 |
| 20-HETE-induced contraction of small coronary arteries depends on the activation of Rho-kinase. | Hypertension (Dallas, Tex. : 1979) 20030301 |
| Glomerular autacoids stimulated by bradykinin regulate efferent arteriole tone. | Kidney international 20030301 |
| Differential regulation of natriuresis by 20-hydroxyeicosatetraenoic Acid in human salt-sensitive versus salt-resistant hypertension. | Circulation 20030204 |
| Quantification of 20-hydroxyeicosatetraenoic acid by colorimetric competitive enzyme linked immunosorbent assay. | Journal of biosciences 20030201 |
| Transfection of CYP4A1 cDNA increases vascular reactivity in renal interlobar arteries. | American journal of physiology. Renal physiology 20030101 |
| Characterization of the CYP4A11 gene, a second CYP4A gene in humans. | Archives of biochemistry and biophysics 20030101 |
| Regulation of renal microvascular 20-hydroxyeicosatetraenoic acid (20-HETE) levels. | Advances in experimental medicine and biology 20030101 |
| Cytochrome P450 arachidonic acid metabolites modulate renal tubular function. | Advances in experimental medicine and biology 20030101 |
| Candida bombicola cells immobilized on patterned lipid films as enzyme sources for the transformation of arachidonic acid to 20-HETE. | Biotechnology progress 20030101 |
| 20-Hydroxyeicosatetraenoic acid potentiates contractile activation of canine basilar artery in response to stretch via protein kinase Calpha-mediated inhibition of calcium-activated potassium channel. | Advances in experimental medicine and biology 20030101 |
| 20-Hydroxyeicosatetraenoic acid potentiates stretch-induced contraction of canine basilar artery via PKC alpha-mediated inhibition of KCa channel. | British journal of pharmacology 20021201 |
| Differential effect of cobalt protoporphyrin on distributions of heme oxygenase in renal structure and on blood pressure in SHR. | Cellular and molecular biology (Noisy-le-Grand, France) 20021201 |
| Nitric oxide contributes to 20-HETE-induced relaxation of pulmonary arteries. | Journal of applied physiology (Bethesda, Md. : 1985) 20021001 |
| Arachidonic acid inhibits K channels in basolateral membrane of the thick ascending limb. | American journal of physiology. Renal physiology 20020901 |
| Antihypertensive effect of mechanism-based inhibition of renal arachidonic acid omega-hydroxylase activity. | American journal of physiology. Regulatory, integrative and comparative physiology 20020901 |
| 20-HETE pathway antagonists inhibit rat small mesenteric artery tone. | Microvascular research 20020901 |
| Integration of hypoxic dilation signaling pathways for skeletal muscle resistance arteries. | American journal of physiology. Regulatory, integrative and comparative physiology 20020801 |
| Renal cytochrome p450 oxygenases and preglomerular vascular response to arachidonic acid and endothelin-1 following ischemia/reperfusion. | The Journal of pharmacology and experimental therapeutics 20020801 |
| Cytochrome P-450 4A isoform expression and 20-HETE synthesis in renal preglomerular arteries. | American journal of physiology. Renal physiology 20020701 |
| Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II. | American journal of physiology. Regulatory, integrative and comparative physiology 20020701 |
| CYP4A mRNA, protein, and product in rat lungs: novel localization in vascular endothelium. | Journal of applied physiology (Bethesda, Md. : 1985) 20020701 |
| Cytochrome P450 pathways of arachidonic acid metabolism. | Current opinion in lipidology 20020601 |
| Arachidonate CYP hydroxylases of kidney contribute to formation of hypertension and maintenance of blood pressure. | Acta pharmacologica Sinica 20020601 |
| The opposite effects of cyclic AMP-protein kinase a signal transduction pathway on renal cortical and medullary Na+,K+-ATPase activity. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20020601 |
| Parenchymal tissue cytochrome P450 4A enzymes contribute to oxygen-induced alterations in skeletal muscle arteriolar tone. | Microvascular research 20020501 |
| Role of ADP-ribose in 11,12-EET-induced activation of K(Ca) channels in coronary arterial smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20020401 |
| 20-HETE contributes to the acute fall in cerebral blood flow after subarachnoid hemorrhage in the rat. | American journal of physiology. Heart and circulatory physiology 20020401 |
| Renal 20-hydroxyeicosatetraenoic acid synthesis during pregnancy. | American journal of physiology. Regulatory, integrative and comparative physiology 20020201 |
| Regulation of cyclooxygenase- and cytochrome p450-derived eicosanoids by heme oxygenase in the rat kidney. | Hypertension (Dallas, Tex. : 1979) 20020201 |
| Role of cytochrome P-450 arachidonate metabolites in endothelin signaling in rat proximal tubule. | American journal of physiology. Renal physiology 20020101 |
| P-450 metabolites of arachidonic acid in the control of cardiovascular function. | Physiological reviews 20020101 |
| Identification of omega hydroxy fatty acids in biological samples as their pentafluoropropyl derivatives by gas chromatography/mass spectrometry with positive and negative ion detection. | Rapid communications in mass spectrometry : RCM 20020101 |
| Discovery of a N'-hydroxyphenylformamidine derivative HET0016 as a potent and selective 20-HETE synthase inhibitor. | Bioorganic & medicinal chemistry letters 20011203 |
| Modulation by 20-HETE of phenylephrine-induced mesenteric artery contraction in spontaneously hypertensive and Wistar-Kyoto rats. | Hypertension (Dallas, Tex. : 1979) 20011201 |
| The CYP450 hydroxylase pathway contributes to P2X receptor-mediated afferent arteriolar vasoconstriction. | American journal of physiology. Heart and circulatory physiology 20011101 |
| Role of prostanoids and 20-HETE in mediating oxygen-induced constriction of skeletal muscle resistance arteries. | Microvascular research 20011101 |
| Cytochrome p450 and vascular homeostasis. | Circulation research 20011026 |
| Effects of protein tyrosine kinase and protein tyrosine phosphatase on apical K(+) channels in the TAL. | American journal of physiology. Cell physiology 20011001 |
| Involvement of cytochrome P450 metabolites in the vascular action of angiotensin II on the afferent arterioles. | Hypertension research : official journal of the Japanese Society of Hypertension 20010901 |
| Phospholipase D activation by norepinephrine is mediated by 12(s)-, 15(s)-, and 20-hydroxyeicosatetraenoic acids generated by stimulation of cytosolic phospholipase a2. tyrosine phosphorylation of phospholipase d2 in response to norepinephrine. | The Journal of biological chemistry 20010511 |
| Cytochrome P450 metabolites of arachidonic acid but not cyclooxygenase-2 metabolites contribute to the pulmonary vascular hyporeactivity in rats with acute Pseudomonas pneumonia. | The Journal of pharmacology and experimental therapeutics 20010501 |
| Determination of cytochrome P450 metabolites of arachidonic acid in coronary venous plasma during ischemia and reperfusion in dogs. | Analytical biochemistry 20010501 |
| Cytochrome P-450 omega-hydroxylase: a potential O(2) sensor in rat arterioles and skeletal muscle cells. | American journal of physiology. Heart and circulatory physiology 20010401 |
| Altered mechanisms underlying hypoxic dilation of skeletal muscle resistance arteries of hypertensive versus normotensive Dahl rats. | Microcirculation (New York, N.Y. : 1994) 20010401 |
| Effects of converting enzyme inhibitors on renal P-450 metabolism of arachidonic acid. | American journal of physiology. Regulatory, integrative and comparative physiology 20010301 |
| 20-HETE modulates myogenic response of skeletal muscle resistance arteries from hypertensive Dahl-SS rats. | American journal of physiology. Heart and circulatory physiology 20010301 |
| 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids and blood pressure. | Current opinion in nephrology and hypertension 20010301 |
| Role of 20-HETE in mediating the effect of dietary K intake on the apical K channels in the mTAL. | American journal of physiology. Renal physiology 20010201 |
| 20-Hydroxyeicosatetraenoic acid mediates angiotensin ii-induced phospholipase d activation in vascular smooth muscle cells. | Hypertension (Dallas, Tex. : 1979) 20010201 |
| 20-HETE contributes to myogenic activation of skeletal muscle resistance arteries in Brown Norway and Sprague-Dawley rats. | Microcirculation (New York, N.Y. : 1994) 20010201 |
| Binding of cytochrome P450 monooxygenase and lipoxygenase pathway products by heart fatty acid-binding protein. | Biochemistry 20010130 |
| CYP4A1 antisense oligonucleotide reduces mesenteric vascular reactivity and blood pressure in SHR. | American journal of physiology. Regulatory, integrative and comparative physiology 20010101 |
| Regulation of preglomerular microvascular 20-hydroxyeicosatetraenoic acid levels by salt depletion. | Medical science monitor : international medical journal of experimental and clinical research 20010101 |
| Relative contributions of cyclooxygenase- and cytochrome P450 omega-hydroxylase-dependent pathways to hypoxic dilation of skeletal muscle resistance arteries. | Journal of vascular research 20010101 |
| Synergistic induction of acyl-CoA oxidase activity, an indicator of peroxisome proliferation, by arachidonic acid and retinoic acid in Morris hepatoma 7800C1 cells. | Biochimica et biophysica acta 19951005 |
| 20-HETE induces hyperglycemia through the cAMP/PKA-PhK-GP pathway. | Molecular endocrinology (Baltimore, Md.) |