6,7-Dimethyl-2-phenylquinoxaline
| Title | Journal |
|---|---|
| AhR-dependent secretion of PDGF-BB by human classically activated macrophages exposed to DEP extracts stimulates lung fibroblast proliferation. | Toxicology and applied pharmacology 20150615 |
| A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. | The Biochemical journal 20130415 |
| Inhibitory effects of resveratrol on PDGF-BB-induced retinal pigment epithelial cell migration via PDGFRβ, PI3K/Akt and MAPK pathways. | PloS one 20130101 |
| Platelet-derived growth factor receptor kinase inhibitor AG-1295 promotes osteoblast differentiation in MC3T3-E1 cells via the Erk pathway. | Bioscience trends 20120601 |
| N⁴-(3-Bromophenyl)-7-(substituted benzyl) pyrrolo[2,3-d]pyrimidines as potent multiple receptor tyrosine kinase inhibitors: design, synthesis, and in vivo evaluation. | Bioorganic & medicinal chemistry 20120401 |
| HB-EGF and PDGF mediate reciprocal interactions of carcinoma cells with cancer-associated fibroblasts to support progression of uterine cervical cancers. | Cancer research 20111101 |
| Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. | Nature biotechnology 20111101 |
| PDGF-β receptor and PKC have no effect on angiotensin II-induced JAK2 and STAT1 phosphorylation in vascular smooth muscle cells under high glucose condition. | Journal of receptor and signal transduction research 20111001 |
| The contribution of a 2-amino group on receptor tyrosine kinase inhibition and antiangiogenic activity in 4-anilinosubstituted pyrrolo[2,3-d]pyrimidines. | Bioorganic & medicinal chemistry letters 20100515 |
| Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors. | Bioorganic & medicinal chemistry 20091015 |
| FGF2 is crucial for the development of bovine luteal endothelial networks in vitro. | Reproduction (Cambridge, England) 20090901 |
| Bovine lactoferrin stimulates human corneal epithelial alkali wound healing in vitro. | Investigative ophthalmology & visual science 20090401 |
| BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3. | Blood 20090305 |
| Modulation of circadian rhythm of DNA synthesis in tumor cells by inhibiting platelet-derived growth factor signaling. | Journal of pharmacological sciences 20080801 |
| Design, synthesis and biological evaluation of substituted pyrrolo[2,3-d]pyrimidines as multiple receptor tyrosine kinase inhibitors and antiangiogenic agents. | Bioorganic & medicinal chemistry 20080515 |
| Potentiation by platelet-derived growth factor-BB of FGF-2-stimulated VEGF release in osteoblasts. | Journal of bone and mineral metabolism 20080101 |
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. | Proceedings of the National Academy of Sciences of the United States of America 20071218 |
| Platelet-derived growth factors and receptors in the rat corpus luteum: localization and identification of an effect on luteogenesis. | Biology of reproduction 20070301 |
| Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[b]furan-2-yl)methanones. | Bioorganic & medicinal chemistry 20070301 |
| Novel bis(1H-indol-2-yl)methanones as potent inhibitors of FLT3 and platelet-derived growth factor receptor tyrosine kinase. | Journal of medicinal chemistry 20060601 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| The role of platelet-derived growth factor receptor in eotaxin signaling of eosinophils. | International archives of allergy and immunology 20060101 |
| Nicotinic and PDGF-receptor function are essential for nicotine-stimulated mitogenesis in human vascular smooth muscle cells. | Journal of cellular biochemistry 20051201 |
| Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor beta receptor. | Journal of molecular biology 20050128 |
| Enforced expression of an Flt3 internal tandem duplication in human CD34+ cells confers properties of self-renewal and enhanced erythropoiesis. | Blood 20050101 |
| Signal transduction of c-Kit receptor tyrosine kinase in CHRF myeloid leukemia cells. | Journal of cancer research and clinical oncology 20041201 |
| Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acquired drug resistance to PTK inhibitors in FLT3-ITD-transformed hematopoietic cells. | Blood 20040315 |
| Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration. | Developmental cell 20031001 |
| Signaling and distribution of NPR-Bi, the human splice form of the natriuretic peptide receptor type B. | American journal of physiology. Renal physiology 20030801 |
| Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells. | Oncogene 20030417 |
| UVB-induced apoptosis in normal human keratinocytes: role of the erbB receptor family. | Experimental cell research 20030401 |
| PDGF and FGF2 regulate oligodendrocyte progenitor responses to demyelination. | Journal of neurobiology 20030215 |
| Platelet-derived growth factor up-regulates the expression of transcription factors NF-E2, GATA-1 and c-Fos in megakaryocytic cell lines. | Cytokine 20030121 |
| Platelet-derived growth factor receptor kinase inhibitor AG1295 and inhibition of experimental proliferative vitreoretinopathy. | Japanese journal of ophthalmology 20030101 |
| Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src. | The Journal of biological chemistry 20021122 |
| Inhibition of aortic allograft vasculopathy by local delivery of platelet-derived growth factor receptor tyrosine-kinase blocker AG-1295. | Transplantation 20021115 |
| Study of the drug release mechanism from tyrphostin AG-1295-loaded nanospheres by in situ and external sink methods. | Journal of controlled release : official journal of the Controlled Release Society 20021030 |
| Inhibition of platelet-derived growth factor actions in the embryonic testis influences normal cord development and morphology. | Biology of reproduction 20020301 |
| Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase. | Journal of medicinal chemistry 20020227 |
| Formulation and delivery mode affect disposition and activity of tyrphostin-loaded nanoparticles in the rat carotid model. | Arteriosclerosis, thrombosis, and vascular biology 20010901 |
| A FLT3 tyrosine kinase inhibitor is selectively cytotoxic to acute myeloid leukemia blasts harboring FLT3 internal tandem duplication mutations. | Blood 20010801 |
| Selective platelet-derived growth factor receptor kinase blockers reverse sis-transformation. | Cancer research 19941201 |