Home Aminos 3-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenol

3-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenol

CAS No.:
211555-08-7
Catalog Number:
AG006Z3B
Molecular Formula:
C16H15N3O3
Molecular Weight:
297.3086
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$255
- +
2mg
99%
1 week
United States
$323
- +
250mg
95%
1 week
United States
$385
- +
1g
95%
1 week
United States
$907
- +
Product Description
Catalog Number:
AG006Z3B
Chemical Name:
3-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenol
CAS Number:
211555-08-7
Molecular Formula:
C16H15N3O3
Molecular Weight:
297.3086
MDL Number:
MFCD02683970
IUPAC Name:
3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
InChI:
InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-4-3-5-11(20)6-10/h3-9,20H,1-2H3,(H,17,18,19)
InChI Key:
BNDYIYYKEIXHNK-UHFFFAOYSA-N
SMILES:
COc1cc2c(ncnc2cc1OC)Nc1cccc(c1)O
Properties
Complexity:
358  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
297.111g/mol
Formal Charge:
0
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
297.314g/mol
Monoisotopic Mass:
297.111g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
76.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3  
Literature
Title Journal
Inhibition of human immunodeficiency virus type-1 by cdk inhibitors. AIDS research and therapy 20100101
Cellular phototoxicity evoked through the inhibition of human ABC transporter ABCG2 by cyclin-dependent kinase inhibitors in vitro. Pharmaceutical research 20090201
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proceedings of the National Academy of Sciences of the United States of America 20071218
Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 2. Identification of small-molecule inhibitors via coupling with virtual screening. Journal of medicinal chemistry 20050505
Global kinase screening. Applications of frontal affinity chromatography coupled to mass spectrometry in drug discovery. Analytical chemistry 20050301
Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 1. Comparison with conventional ELISA. Journal of medicinal chemistry 20041007
Treatment of post-bone marrow transplant acute graft-versus-host disease with a rationally designed JAK3 inhibitor. Leukemia & lymphoma 20020701
4-[3-Bromo-4-hydroxyphenyl)amino]-6,7-dimethoxyquinazolin-1-ium chloride methanol solvate and 4-[(3-hydroxyphenyl)amino]-6,7-dimethoxy-1-quinazolinium chloride. Acta crystallographica. Section C, Crystal structure communications 20010101
Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors. Journal of medicinal chemistry 19991230
Properties