Home Aminos 2-amino-2-methyl-butanoic acid

2-amino-2-methyl-butanoic acid

CAS No.:
465-58-7
Catalog Number:
AG00724Y
Molecular Formula:
C5H11NO2
Molecular Weight:
117.1463
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Product Description
Catalog Number:
AG00724Y
Chemical Name:
2-amino-2-methyl-butanoic acid
CAS Number:
465-58-7
Molecular Formula:
C5H11NO2
Molecular Weight:
117.1463
MDL Number:
MFCD00272968
IUPAC Name:
2-amino-2-methylbutanoic acid
InChI:
InChI=1S/C5H11NO2/c1-3-5(2,6)4(7)8/h3,6H2,1-2H3,(H,7,8)
InChI Key:
GCHPUFAZSONQIV-UHFFFAOYSA-N
SMILES:
CC(C(=O)O)(CC)N
NSC Number:
1019
Properties
Complexity:
103  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
117.079g/mol
Formal Charge:
0
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
117.148g/mol
Monoisotopic Mass:
117.079g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
63.3A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.3  
Literature
Title Journal
GABA(B) receptor-mediated selective peripheral analgesia by the non-proteinogenic amino acid, isovaline. Neuroscience 20120628
R-Isovaline: a subtype-specific agonist at GABA(B)-receptors? Neuroscience 20120110
Photostability of Iiovaline and its precursor 5-Ethyl-5- methylhydantoin exposed to simulated space radiations. International journal of molecular sciences 20120101
Isovaline, a rare amino acid, has anticonvulsant properties in two in vitro hippocampal seizure models by increasing interneuronal activity. Epilepsia 20111101
Distribution and stable isotopic composition of amino acids from fungal peptaibiotics: assessing the potential for meteoritic contamination. Astrobiology 20110301
Configurational assignment of D- and L-isovalines in intact, natural, and synthetic peptides by 2D-NMR spectroscopy. Chemistry & biodiversity 20100601
Analgesic properties of the novel amino acid, isovaline. Anesthesia and analgesia 20100401
(S)-alpha-methyl,alpha-amino acids: a new stereocontrolled synthesis. Amino acids 20100301
Isovaline causes inhibition by increasing potassium conductance in thalamic neurons. Neuroscience 20091215
Aib and iva in the biosphere: neither rare nor necessarily extraterrestrial. Chemistry & biodiversity 20090101
Studies on the selective trifluoroacetolytic scission of native peptaibols and model peptides using HPLC and ESI-CID-MS. Chemistry & biodiversity 20081101
Prebiotic amino acids as asymmetric catalysts. Science (New York, N.Y.) 20040220
A simple and rapid enzymatic assay for the branched-chain alpha-ketoacid dehydrogenase complex using high-performance liquid chromatography. Journal of inherited metabolic disease 20040101
Antibodies directed against L and D isovaline using a chemical derivatizing reagent for the measurement of their enantiomeric ratio in extraterrestrial samples: first step-production and characterization of antibodies. Chirality 20020601
Properties