Methaneseleninic acid(6CI,8CI,9CI)
| Title | Journal |
|---|---|
| Methylseleninic acid and sodium selenite induce severe ER stress and subsequent apoptosis through UPR activation in PEL cells. | Chemico-biological interactions 20170325 |
| Crucial role of macrophage selenoproteins in experimental colitis. | Journal of immunology (Baltimore, Md. : 1950) 20141001 |
| Methylseleninic acid potentiates multiple types of cancer cells to ABT-737-induced apoptosis by targeting Mcl-1 and Bad. | Apoptosis : an international journal on programmed cell death 20120401 |
| Targeting Werner syndrome protein sensitizes U-2 OS osteosarcoma cells to selenium-induced DNA damage response and necrotic death. | Biochemical and biophysical research communications 20120330 |
| Methylseleninic acid downregulates hypoxia-inducible factor-1α in invasive prostate cancer. | International journal of cancer 20120315 |
| Methylseleninic acid is a novel suppressor of aromatase expression. | The Journal of endocrinology 20120201 |
| Methylseleninic acid antagonizes the cytotoxic effect of bortezomib in mantle cell lymphoma cell lines through modulation of Bcl-2 family proteins. | British journal of haematology 20120101 |
| Methylseleninic acid enhances paclitaxel efficacy for the treatment of triple-negative breast cancer. | PloS one 20120101 |
| Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition. | BMC cancer 20120101 |
| Comparison of different selenocompounds with respect to nutritional value vs. toxicity using liver cells in culture. | The Journal of nutritional biochemistry 20111001 |
| Lobe-specific lineages of carcinogenesis in the transgenic adenocarcinoma of mouse prostate and their responses to chemopreventive selenium. | The Prostate 20110915 |
| Methylseleninic acid inhibits HDAC activity in diffuse large B-cell lymphoma cell lines. | Cancer chemotherapy and pharmacology 20110901 |
| Selenoprotein-dependent up-regulation of hematopoietic prostaglandin D2 synthase in macrophages is mediated through the activation of peroxisome proliferator-activated receptor (PPAR) gamma. | The Journal of biological chemistry 20110805 |
| Capabilities of HPLC with APEX-Q nebulisation ICP-MS and ESI MS/MS to compare selenium uptake and speciation of non-malignant with different B cell lymphoma lines. | Analytical and bioanalytical chemistry 20110201 |
| Mouse prostate proteomes are differentially altered by supranutritional intake of four selenium compounds. | Nutrition and cancer 20110101 |
| Methaneseleninic acid is a substrate for truncated mammalian thioredoxin reductase: implications for the catalytic mechanism and redox signaling. | Biochemistry 20101207 |
| Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells. | The Journal of biological chemistry 20101022 |
| Antioxidant and anticancer properties and mechanisms of inorganic selenium, oxo-sulfur, and oxo-selenium compounds. | Cell biochemistry and biophysics 20100901 |
| Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model. | Cancer prevention research (Philadelphia, Pa.) 20100801 |
| Telomerase as an important target of androgen signaling blockade for prostate cancer treatment. | Molecular cancer therapeutics 20100701 |
| Selenium compounds activate early barriers of tumorigenesis. | The Journal of biological chemistry 20100416 |
| Selenomethionine or methylseleninic acid inhibits mutagenesis of a reporter gene in mouse bone marrow. | Anticancer research 20100201 |
| Model mechanisms of sulfhydryl oxidation by methyl- and benzeneseleninic acid, inhibitors of zinc-finger transcription factors. | Journal of inorganic biochemistry 20100101 |
| Survivin gene silencing sensitizes prostate cancer cells to selenium growth inhibition. | BMC cancer 20100101 |
| Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers. | Molecular cancer 20100101 |
| Thioredoxin reductase 1 ablation sensitizes colon cancer cells to methylseleninate-mediated cytotoxicity. | Toxicology and applied pharmacology 20091215 |
| Selenium modifies the osteoblast inflammatory stress response to bone metastatic breast cancer. | Carcinogenesis 20091101 |
| Negation of the cancer-preventive actions of selenium by over-expression of protein kinase Cepsilon and selenoprotein thioredoxin reductase. | Carcinogenesis 20090901 |
| In vivo molecular mediators of cancer growth suppression and apoptosis by selenium in mammary and prostate models: lack of involvement of gadd genes. | Molecular cancer therapeutics 20090301 |
| Chemotherapeutic sensitization by endoplasmic reticulum stress: increasing the efficacy of taxane against prostate cancer. | Cancer biology & therapy 20090101 |
| Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to selenium-induced apoptosis in prostate cancer cells. | The Journal of biological chemistry 20081212 |
| Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients. | International journal of cancer 20080915 |
| Methylseleninic acid synergizes with tamoxifen to induce caspase-mediated apoptosis in breast cancer cells. | Molecular cancer therapeutics 20080901 |
| Preferential organ distribution of methylselenol source Se-methylselenocysteine relative to methylseleninic acid. | Toxicology and applied pharmacology 20080215 |
| Methylseleninic acid enhances taxane drug efficacy against human prostate cancer and down-regulates antiapoptotic proteins Bcl-XL and survivin. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080215 |
| Kruppel-like factor 4 is a novel mediator of selenium in growth inhibition. | Molecular cancer research : MCR 20080201 |
| Methylation and demethylation of intermediates selenide and methylselenol in the metabolism of selenium. | Toxicology and applied pharmacology 20080115 |
| Methylseleninic acid inhibits microvascular endothelial G1 cell cycle progression and decreases tumor microvessel density. | International journal of cancer 20080101 |
| Vitamin E analog alpha-TEA, methylseleninic acid, and trans-resveratrol in combination synergistically inhibit human breast cancer cell growth. | Nutrition and cancer 20080101 |
| Novel potent organoselenium compounds as cytotoxic agents in prostate cancer cells. | Bioorganic & medicinal chemistry letters 20071215 |
| Chemosensitization of B-cell lymphomas by methylseleninic acid involves nuclear factor-kappaB inhibition and the rapid generation of other selenium species. | Cancer research 20071115 |
| Methylseleninic acid enhances the effect of etoposide to inhibit prostate cancer growth in vivo. | International journal of cancer 20070915 |
| Selenium inhibition of survivin expression by preventing Sp1 binding to its promoter. | Molecular cancer therapeutics 20070901 |
| Differential involvement of reactive oxygen species in apoptosis induced by two classes of selenium compounds in human prostate cancer cells. | International journal of cancer 20070501 |
| Methylseleninic acid inhibits PMA-stimulated pro-MMP-2 activation mediated by MT1-MMP expression and further tumor invasion through suppression of NF-kappaB activation. | Carcinogenesis 20070401 |
| Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates. | Molecular cancer therapeutics 20070301 |
| Selenomethionine induced transcriptional programs in human prostate cancer cells. | The Journal of urology 20070201 |
| Doxorubicin and selenium cooperatively induce fas signaling in the absence of Fas/Fas ligand interaction. | Anticancer research 20070101 |
| Availability and metabolism of 77Se-methylseleninic acid compared simultaneously with those of three related selenocompounds. | Toxicology and applied pharmacology 20061115 |
| Inhibition of androgen receptor signaling by selenite and methylseleninic acid in prostate cancer cells: two distinct mechanisms of action. | Molecular cancer therapeutics 20060801 |
| The activity of methylated and non-methylated selenium species in lymphoma cell lines and primary tumours. | Annals of oncology : official journal of the European Society for Medical Oncology 20060501 |
| Mechanisms of selenium down-regulation of androgen receptor signaling in prostate cancer. | Molecular cancer therapeutics 20060401 |
| Delineating the mechanism by which selenium deactivates Akt in prostate cancer cells. | Molecular cancer therapeutics 20060201 |
| Enhanced selenium effect on growth arrest by BiP/GRP78 knockdown in p53-null human prostate cancer cells. | Oncogene 20060126 |
| Neural network-based analysis of thiol proteomics data in identifying potential selenium targets. | Preparative biochemistry & biotechnology 20060101 |
| Endoplasmic reticulum stress signal mediators are targets of selenium action. | Cancer research 20051001 |
| PKB/AKT and ERK regulation of caspase-mediated apoptosis by methylseleninic acid in LNCaP prostate cancer cells. | Carcinogenesis 20050801 |
| Selenium disrupts estrogen receptor (alpha) signaling and potentiates tamoxifen antagonism in endometrial cancer cells and tamoxifen-resistant breast cancer cells. | Molecular cancer therapeutics 20050801 |
| Attenuation of estrogen receptor alpha (ERalpha) signaling by selenium in breast cancer cells via downregulation of ERalpha gene expression. | Breast cancer research and treatment 20050801 |
| Androgen receptor signaling intensity is a key factor in determining the sensitivity of prostate cancer cells to selenium inhibition of growth and cancer-specific biomarkers. | Molecular cancer therapeutics 20050701 |
| Selenium disrupts estrogen signaling by altering estrogen receptor expression and ligand binding in human breast cancer cells. | Cancer research 20050415 |
| Microarray Data Mining for Potential Selenium Targets in Chemoprevention of Prostate Cancer. | Cancer genomics & proteomics 20050401 |
| Methylseleninic acid potentiates apoptosis induced by chemotherapeutic drugs in androgen-independent prostate cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050315 |
| Chemical forms of selenium for cancer prevention. | Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20050101 |
| Methyl selenium metabolites decrease prostate-specific antigen expression by inducing protein degradation and suppressing androgen-stimulated transcription. | Molecular cancer therapeutics 20040501 |
| Diverse effects of methylseleninic acid on the transcriptional program of human prostate cancer cells. | Molecular biology of the cell 20040201 |
| Prostate specific antigen expression is down-regulated by selenium through disruption of androgen receptor signaling. | Cancer research 20040101 |
| Selenium compounds regulate p53 by common and distinctive mechanisms. | Anticancer research 20040101 |
| Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array. | Cancer research 20030101 |
| Distinct effects of methylseleninic acid versus selenite on apoptosis, cell cycle, and protein kinase pathways in DU145 human prostate cancer cells. | Molecular cancer therapeutics 20021001 |
| Intracellular glutathione is a cofactor in methylseleninic acid-induced apoptotic cell death of human hepatoma HEPG(2) cells. | Free radical biology & medicine 20020815 |
| Induction of caspase-mediated apoptosis and cell-cycle G1 arrest by selenium metabolite methylselenol. | Molecular carcinogenesis 20020701 |
| Methylseleninate is a substrate rather than an inhibitor of mammalian thioredoxin reductase. Implications for the antitumor effects of selenium. | The Journal of biological chemistry 20020322 |
| Identification of molecular targets associated with selenium-induced growth inhibition in human breast cells using cDNA microarrays. | Cancer research 20020201 |
| Evidence of a field effect associated with mammary cancer chemoprevention by methylseleninic acid. | Anticancer research 20020101 |
| Antimitogenic and proapoptotic activities of methylseleninic acid in vascular endothelial cells and associated effects on PI3K-AKT, ERK, JNK and p38 MAPK signaling. | Cancer research 20011001 |
| Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells. | Cancer research 20010401 |
| Methylseleninic acid, a potent growth inhibitor of synchronized mouse mammary epithelial tumor cells in vitro. | Biochemical pharmacology 20010201 |
| Dimethyldiselenide and methylseleninic acid generate superoxide in an in vitro chemiluminescence assay in the presence of glutathione: implications for the anticarcinogenic activity of L-selenomethionine and L-Se-methylselenocysteine. | Nutrition and cancer 20010101 |