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Home Other Building Blocks 7-Allyl-78-dihydro-8-oxoguanosine

7-Allyl-78-dihydro-8-oxoguanosine

CAS No.:
121288-39-9
Catalog Number:
AG009ELU
Molecular Formula:
C13H17N5O6
Molecular Weight:
339.3040
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
≥98%
1 week
United States
$91
- +
10mg
≥98%
1 week
United States
$123
- +
25mg
≥98%
1 week
United States
$153
- +
50mg
≥98%
1 week
United States
$175
- +
Product Description
Catalog Number:
AG009ELU
Chemical Name:
7-Allyl-78-dihydro-8-oxoguanosine
CAS Number:
121288-39-9
Molecular Formula:
C13H17N5O6
Molecular Weight:
339.3040
MDL Number:
MFCD00867591
IUPAC Name:
2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-prop-2-enyl-1H-purine-6,8-dione
InChI:
InChI=1S/C13H17N5O6/c1-2-3-17-6-9(15-12(14)16-10(6)22)18(13(17)23)11-8(21)7(20)5(4-19)24-11/h2,5,7-8,11,19-21H,1,3-4H2,(H3,14,15,16,22)/t5-,7-,8-,11-/m1/s1
InChI Key:
VDCRFBBZFHHYGT-IOSLPCCCSA-N
SMILES:
C=CCn1c(=O)n(c2c1c(=O)nc([nH]2)N)C1OC(C(C1O)O)CO
UNII:
9CAS0V66OI
Properties
Complexity:
661  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
339.118g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0
Molecular Weight:
339.308g/mol
Monoisotopic Mass:
339.118g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
161A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.7  
Literature
Title Journal
Toll-like receptor 7 ligands inhibit influenza A infection in chickens. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20120101
Loxoribine, a selective Toll-like receptor 7 agonist, induces maturation of human monocyte-derived dendritic cells and stimulates their Th-1- and Th-17-polarizing capability. International immunopharmacology 20101101
Toll-like receptors: role in dermatological disease. Mediators of inflammation 20100101
Toll-like receptor 2 agonists inhibit human fibrocyte differentiation. Fibrogenesis & tissue repair 20100101
Disparate expression of IL-12 by SJL/J and B10.S macrophages during Theiler's virus infection is associated with activity of TLR7 and mitogen-activated protein kinases. Microbes and infection 20050201
The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. European journal of immunology 20031101
Loxoribine (7-allyl-8-oxoguanosine) activates natural killer cells and primes cytolytic precursor cells for activation by IL-2. Journal of immunology (Baltimore, Md. : 1950) 19930915
Properties