(4S,7S,10S,13S)-7-(2-Carboxyethyl)-4-(carboxymethyl)-13-formyl-10-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid
| Title | Journal |
|---|---|
| Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells. | Chemico-biological interactions 20160625 |
| Ac-tLeu-Asp-H is the minimal and highly effective human caspase-3 inhibitor: biological and in silico studies. | Amino acids 20150101 |
| Cordycepin induces apoptosis of C6 glioma cells through the adenosine 2A receptor-p53-caspase-7-PARP pathway. | Chemico-biological interactions 20140605 |
| Role of heteromeric gap junctions in the cytotoxicity of cisplatin. | Toxicology 20130809 |
| Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. | American journal of physiology. Lung cellular and molecular physiology 20130415 |
| Differential proteomic analysis of HL60 cells treated with secalonic acid F reveals caspase 3-induced cleavage of Rho GDP dissociation inhibitor 2. | Oncology reports 20121201 |
| Spatial and temporal nature of reactive oxygen species production and programmed cell death in elm (Ulmus pumila L.) seeds during controlled deterioration. | Plant, cell & environment 20121101 |
| Induction of apoptosis by 7-piperazinethylchrysin in HCT-116 human colon cancer cells. | Oncology reports 20121101 |
| Age-related cataracts: homocysteine coupled endoplasmic reticulum stress and suppression of Nrf2-dependent antioxidant protection. | Chemico-biological interactions 20121025 |
| The proteasome is responsible for caspase-3-like activity during xylem development. | The Plant journal : for cell and molecular biology 20121001 |
| The furano norclerodane diterpenoid disobulbin-D induces apoptosis in normal human liver L-02 cells. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20120901 |
| Pro-apoptotic effects of tepoxalin, a cyclooxygenase/lipoxygenase dual inhibitor, on canine synovial fibroblasts. | The Journal of veterinary medical science 20120601 |
| Modulation of histone deacetylase attenuates naloxone-precipitated opioid withdrawal syndrome. | Naunyn-Schmiedeberg's archives of pharmacology 20120601 |
| Selective mGluR1 antagonist EMQMCM inhibits the kainate-induced excitotoxicity in primary neuronal cultures and in the rat hippocampus. | Neurotoxicity research 20120501 |
| NO, ROS, and cell death associated with caspase-like activity increase in stress-induced microspore embryogenesis of barley. | Journal of experimental botany 20120301 |
| Tipifarnib and tanespimycin show synergic proapoptotic activity in U937 cells. | Journal of cancer research and clinical oncology 20120301 |
| Phytochemical Composition, Antioxidant Activity, and Neuroprotective Effect of Terminalia chebula Retzius Extracts. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Phytochemical characteristics, free radical scavenging activities, and neuroprotection of five medicinal plant extracts. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Tanshinone IIA Inhibits Growth of Keratinocytes through Cell Cycle Arrest and Apoptosis: Underlying Treatment Mechanism of Psoriasis. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Jaceosidin Induces Apoptosis in U87 Glioblastoma Cells through G2/M Phase Arrest. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C. | PloS one 20120101 |
| Increased activity of cell surface peptidases in HeLa cells undergoing UV-induced apoptosis is not mediated by caspase 3. | International journal of molecular sciences 20120101 |
| β-Caryophyllene, a Compound Isolated from the Biblical Balm of Gilead (Commiphora gileadensis), Is a Selective Apoptosis Inducer for Tumor Cell Lines. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Injurious effects of curcumin on maturation of mouse oocytes, fertilization and fetal development via apoptosis. | International journal of molecular sciences 20120101 |
| Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons. | Neurotoxicology 20111201 |
| Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells. | Oncotarget 20111101 |
| 5-Aza-2'-deoxycytidine stress response and apoptosis in prostate cancer. | Clinical epigenetics 20110801 |
| Salinomycin induces calpain and cytochrome c-mediated neuronal cell death. | Cell death & disease 20110601 |
| Caudatin-2,6-dideoxy-3-O-methy-β-D-cymaropyranoside 1 induced apoptosis through caspase 3-dependent pathway in human hepatoma cell line SMMC7721. | Phytotherapy research : PTR 20110501 |
| Reactive oxygen species and nitric oxide mediate actin reorganization and programmed cell death in the self-incompatibility response of papaver. | Plant physiology 20110501 |
| The glycan-binding protein galectin-1 controls survival of epithelial cells along the crypt-villus axis of small intestine. | Cell death & disease 20110501 |
| Synthesis and evaluation of isatin analogs as caspase-3 inhibitors: introduction of a hydrophilic group increases potency in a whole cell assay. | Bioorganic & medicinal chemistry letters 20110415 |
| Levosimendan modulates programmed forms of cell death through K(ATP) channels and nitric oxide. | Journal of cardiovascular pharmacology 20110201 |
| Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway. | Molecular neurodegeneration 20110101 |
| A Sequential Model of Host Cell Killing and Phagocytosis by Entamoeba histolytica. | Journal of parasitology research 20110101 |
| Mycobacterium indicus pranii supernatant induces apoptotic cell death in mouse peritoneal macrophages in vitro. | PloS one 20110101 |
| Ion channel inhibitors block caspase activation by mechanisms other than restoring intracellular potassium concentration. | Cell death & disease 20110101 |
| Sex-specific activation of cell death signalling pathways in cerebellar granule neurons exposed to oxygen glucose deprivation followed by reoxygenation. | ASN neuro 20110101 |
| Leea indica Ethyl Acetate Fraction Induces Growth-Inhibitory Effect in Various Cancer Cell Lines and Apoptosis in Ca Ski Human Cervical Epidermoid Carcinoma Cells. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein via caspase-3 cascade. | Molecular cancer 20110101 |
| Interferon gamma activated macrophages kill mycobacteria by nitric oxide induced apoptosis. | PloS one 20110101 |
| Caspase-3, myogenic transcription factors and cell cycle inhibitors are regulated by leukemia inhibitory factor to mediate inhibition of myogenic differentiation. | Skeletal muscle 20110101 |
| Cap-independent translation promotes C. elegans germ cell apoptosis through Apaf-1/CED-4 in a caspase-dependent mechanism. | PloS one 20110101 |
| Fucoidan extract induces apoptosis in MCF-7 cells via a mechanism involving the ROS-dependent JNK activation and mitochondria-mediated pathways. | PloS one 20110101 |
| Decreases in CD31 and CD47 levels on the cell surface during etoposide-induced Jurkat cell apoptosis. | Biological & pharmaceutical bulletin 20110101 |
| An in vivo root hair assay for determining rates of apoptotic-like programmed cell death in plants. | Plant methods 20110101 |
| A short caspase-3 isoform inhibits chemotherapy-induced apoptosis by blocking apoptosome assembly. | PloS one 20110101 |
| Programmed Cell Death in the Leaves of the Arabidopsis Spontaneous Necrotic Spots (sns-D) Mutant Correlates with Increased Expression of the Eukaryotic Translation Initiation Factor eIF4B2. | Frontiers in plant science 20110101 |
| [The effect of caspase-3 inhibitor on the concentrations of serum inflammatory cytokines in sepsis related acute kidney injury induced by peritoneal cavity infection in mice]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20101201 |
| Porphyromonas gingivalis peptidoglycans induce excessive activation of the innate immune system in silkworm larvae. | The Journal of biological chemistry 20101022 |
| Salt stress induces programmed cell death in Thellungiella halophila suspension-cultured cells. | Journal of plant physiology 20100915 |
| Synthesis and evaluation of vinyl sulfones as caspase-3 inhibitors. A structure-activity study. | European journal of medicinal chemistry 20100901 |
| Chrysin blocks topotecan-induced apoptosis in Caco-2 cells in spite of inhibition of ABC-transporters. | Biochemical pharmacology 20100815 |
| MEK-ERK-dependent multiple caspase activation by mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma cell death. | Cell death & disease 20100701 |
| Role of individual caspases induced by astrovirus on the processing of its structural protein and its release from the cell through a non-lytic mechanism. | Virology 20100605 |
| Inhibition of caspase-3 differentially affects vascular smooth muscle cell apoptosis in the concave versus convex aortic sites in ascending aneurysms with a bicuspid aortic valve. | Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 20100520 |
| Past, present and future therapeutics for cerebellar ataxias. | Current neuropharmacology 20100301 |
| 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-gamma-dependent and mediated by the caspase-3-dependent apoptotic pathway. | The FEBS journal 20100201 |
| In vitro photodynamic therapy with chlorin e6 leads to apoptosis of human vascular smooth muscle cells. | Archivum immunologiae et therapiae experimentalis 20100201 |
| Activation of PERK signaling attenuates Abeta-mediated ER stress. | PloS one 20100101 |
| Targeting mitochondrial cell death pathway to overcome drug resistance with a newly developed iron chelate. | PloS one 20100101 |
| Cord blood stem cell-mediated induction of apoptosis in glioma downregulates X-linked inhibitor of apoptosis protein (XIAP). | PloS one 20100101 |
| Caspase inhibitors affect the kinetics and dimensions of tracheary elements in xylogenic Zinnia (Zinnia elegans) cell cultures. | BMC plant biology 20100101 |
| Cytotoxicity screening of Bangladeshi medicinal plant extracts on pancreatic cancer cells. | BMC complementary and alternative medicine 20100101 |
| Antiproliferative and pro-apoptotic effects afforded by novel Src-kinase inhibitors in human neuroblastoma cells. | BMC cancer 20100101 |
| Apoptotic markers in protozoan parasites. | Parasites & vectors 20100101 |
| Hazardous apoptotic effects of 2-bromopropane on maturation of mouse oocytes, fertilization, and fetal development. | International journal of molecular sciences 20100101 |
| Prevention of hyperglycemia-induced myocardial apoptosis by gene silencing of Toll-like receptor-4. | Journal of translational medicine 20100101 |
| Endoplasmic reticulum stress associated with caspases-4 and -2 mediates korbazol-induced B-chronic lymphocytic leukemia cell apoptosis. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20100101 |
| AMP-activated protein kinase activation during cardioplegia-induced hypoxia/reoxygenation injury attenuates cardiomyocytic apoptosis via reduction of endoplasmic reticulum stress. | Mediators of inflammation 20100101 |
| Recombinant YopJ induces apoptosis in murine peritoneal macrophages in vitro: involvement of mitochondrial death pathway. | International immunology 20091101 |
| Altered expression of glycoproteins on the cell surface of Jurkat cells during etoposide-induced apoptosis: shedding and intracellular translocation of glycoproteins. | Biochimica et biophysica acta 20091001 |
| Ginkgolide B induces apoptosis via activation of JNK and p21-activated protein kinase 2 in mouse embryonic stem cells. | Annals of the New York Academy of Sciences 20090801 |
| Cilostazol protects endothelial cells against lipopolysaccharide-induced apoptosis through ERK1/2- and P38 MAPK-dependent pathways. | The Korean journal of internal medicine 20090601 |
| Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6. | Journal of medicinal chemistry 20090423 |
| A secreted caspase-3-substrate-cleaving activity at low pH belongs to cathepsin B: a study on primary brain cell cultures. | Biochemistry. Biokhimiia 20090301 |
| Multiple signal transduction pathways in okadaic acid induced apoptosis in HeLa cells. | Toxicology 20090204 |
| Mechanism of induction of muscle protein loss by hyperglycaemia. | Experimental cell research 20090101 |
| IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin. | PloS one 20090101 |
| Oxaprozin-induced apoptosis on CD40 ligand-treated human primary monocytes is associated with the modulation of defined intracellular pathways. | Journal of biomedicine & biotechnology 20090101 |
| Neurological and neurobehavioral assessment of experimental subarachnoid hemorrhage. | BMC neuroscience 20090101 |
| Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death. | PloS one 20090101 |
| Effects of retinoic acid isomers on apoptosis and enzymatic antioxidant system in human breast cancer cells. | Nutrition research and practice 20090101 |
| Human caspase-3 inhibition by Z-tLeu-Asp-H: tLeu(P2) counterbalances Asp(P4) and Glu(P3) specific inhibitor truncation. | Biochemical and biophysical research communications 20081219 |
| As2O3 toxicity in rat hepatocytes: manifestation of caspase-mediated apoptosis. | Toxicology and industrial health 20081101 |
| Opposing roles for caspase and calpain death proteases in L-glutamate-induced oxidative neurotoxicity. | Toxicology and applied pharmacology 20081015 |
| Leptosphaeria maculans elicits apoptosis coincident with leaf lesion formation and hyphal advance in Brassica napus. | Molecular plant-microbe interactions : MPMI 20080901 |
| [Effects of p,p'-DDE and beta-BHC on the apoptosis of Sertoli cells in vitro]. | Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20080901 |
| The effect of recombinant caspase 3 on myofibrillar proteins in porcine skeletal muscle. | Animal : an international journal of animal bioscience 20080801 |
| Arsenic trioxide-induced apoptosis in H9c2 cardiomyocytes: implications in cardiotoxicity. | Basic & clinical pharmacology & toxicology 20080501 |
| Caffeine induces cell death via activation of apoptotic signal and inactivation of survival signal in human osteoblasts. | International journal of molecular sciences 20080501 |
| alpha-Amino-3-hydroxy-5-methyl-4-isoxazole propionate attenuates glutamate-induced caspase-3 cleavage via regulation of glycogen synthase kinase 3beta. | Journal of neuroscience research 20080401 |
| Effects of in vitro brevetoxin exposure on apoptosis and cellular metabolism in a leukemic T cell line (Jurkat). | Marine drugs 20080301 |
| PI3K/AKT inhibition induces caspase-dependent apoptosis in HTLV-1-transformed cells. | Virology 20080120 |
| Epigallocatechin gallate protects against oxidative stress-induced mitochondria-dependent apoptosis in human lens epithelial cells. | Molecular vision 20080101 |
| Interaction of the HMG-CoA reductase inhibitor lovastatin and nitric oxide in cardiomyocyte cell death. | Pharmacology 20080101 |
| The role of Ca2+ in baicalein-induced apoptosis in human breast MDA-MB-231 cancer cells through mitochondria- and caspase-3-dependent pathway. | Anticancer research 20080101 |
| Cobalt protoporpyhrin reduces caspase-3,-7 enzyme activity in neonatal porcine islets, but does not inhibit cell death induced by TNF-alpha. | Cell transplantation 20080101 |
| Synapse-specific plasticity in command neurons during learning of edible snails under the action of caspase inhibitors. | Bulletin of experimental biology and medicine 20071201 |
| The dichloromethane fraction of Stemona tuberosa Lour inhibits tumor cell growth and induces apoptosis of human medullary thyroid carcinoma cells. | Biologics : targets & therapy 20071201 |
| Inhibition of angiogenic tubule formation and induction of apoptosis in human endothelial cells by the selective cyclooxygenase-2 inhibitor 5-bromo-2-(4-fluorophenyl)-3-(methylsulfonyl) thiophene (DuP-697). | European journal of pharmacology 20071114 |
| Procaspase-3 activation by a metalloprotease secreted from Vibrio vulnificus. | International journal of molecular medicine 20071001 |
| Revival of apoptotic cells that display early-stage dynamic membrane blebbing. | FEBS letters 20070918 |
| Analysis of aclarubicin-induced cell death in human fibroblasts. | Cell biology international 20070901 |
| Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. | The FEBS journal 20070901 |
| Enhanced expression of membrane-associated sialidase Neu3 decreases GD3 and increases GM3 on the surface of Jurkat cells during etoposide-induced apoptosis. | Biological & pharmaceutical bulletin 20070901 |
| Mechanism of tert-butylhydroperoxide induced cytotoxicity in U-937 macrophages by alteration of mitochondrial function and generation of ROS. | Toxicology in vitro : an international journal published in association with BIBRA 20070801 |
| Inhibition of UVA-induced apoptotic signaling pathway by polypeptide from Chlamys farreri in human HaCaT keratinocytes. | Radiation and environmental biophysics 20070801 |
| GP7 induces internucleosomal DNA fragmentation independent of caspase activation and DNA fragmentation factor in NB4 cells. | Oncology reports 20070701 |
| Heat stress: an inducer of programmed cell death in Chlorella saccharophila. | Plant & cell physiology 20070701 |
| Molecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid. | Environmental health perspectives 20070501 |
| Endogenously generated hydrogen peroxide induces apoptosis via mitochondrial damage independent of NF-kappaB and p53 activation in bovine embryos. | Theriogenology 20070415 |
| Infection of tobacco with different Pseudomonas syringae pathovars leads to distinct morphotypes of programmed cell death. | The Plant journal : for cell and molecular biology 20070401 |
| Cadmium induces apoptosis in the human osteoblast-like cell line Saos-2. | Journal of toxicology and environmental health. Part A 20070401 |
| cAMP mediates ammonia-induced programmed cell death in the microglial cell line BV-2. | The European journal of neuroscience 20070401 |
| Relationship between subcellular localisation of Foscan and caspase activation in photosensitised MCF-7 cells. | British journal of cancer 20070326 |
| Emodin induces apoptosis through caspase 3-dependent pathway in HK-2 cells. | Toxicology 20070307 |
| Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070301 |
| Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO. | BMC pharmacology 20070101 |
| Calcium-mediated perception and defense responses activated in plant cells by metabolite mixtures secreted by the biocontrol fungus Trichoderma atroviride. | BMC plant biology 20070101 |
| Inhibitory effects of 1,25-dihydroxyvitamin D3 and its low-calcemic analogues on staurosporine-induced apoptosis. | Pharmacological reports : PR 20070101 |
| Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth. | PloS one 20070101 |
| Cadmium-induced apoptosis in rat hepatocytes does not necessarily involve caspase-dependent pathways. | Toxicology in vitro : an international journal published in association with BIBRA 20061201 |
| The possible role of caspase-3 in pathological and physiological cardiac hypertrophy in rats. | Basic & clinical pharmacology & toxicology 20061201 |
| Characterization of mitochondria in cisplatin-resistant human ovarian carcinoma cells. | Oncology reports 20061101 |
| Induction of apoptosis by 25-hydroxycholesterol in adult rat Leydig cells: protective effect of 17beta-estradiol. | Reproductive toxicology (Elmsford, N.Y.) 20061101 |
| 150 kDa glycoprotein isolated from Solanum nigrum Linne stimulates caspase-3 activation and reduces inducible nitric oxide production in HCT-116 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20061001 |
| Green tea polyphenols-induced apoptosis in human osteosarcoma SAOS-2 cells involves a caspase-dependent mechanism with downregulation of nuclear factor-kappaB. | Toxicology and applied pharmacology 20061001 |
| Role of mechanical stress in the form of cardiomyocyte death during the early phase of reperfusion. | Circulation journal : official journal of the Japanese Circulation Society 20061001 |
| [Diallyl trisulfide induces apoptosis of human gastric cancer cell line MGC803 through caspase-3 pathway]. | Ai zheng = Aizheng = Chinese journal of cancer 20061001 |
| Melatonin protects against hydrogen peroxide-induced cell death signaling in SH-SY5Y cultured cells: involvement of nuclear factor kappa B, Bax and Bcl-2. | Journal of pineal research 20060901 |
| Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition. | Journal of molecular biology 20060714 |
| Nitric oxide and peroxynitrite induce cellular death in bovine chromaffin cells: evidence for a mixed necrotic and apoptotic mechanism with caspases activation. | Journal of neuroscience research 20060701 |
| Caspase activation contributes to endotoxin-induced diaphragm weakness. | Journal of applied physiology (Bethesda, Md. : 1985) 20060601 |
| Induction of apoptosis by Radix Paeoniae Alba extract through cytochrome c release and the activations of caspase-9 and caspase-3 in HL-60 cells. | Biological & pharmaceutical bulletin 20060601 |
| Importance of uterine cell death, renewal, and their hormonal regulation in hamsters that show progesterone-dependent implantation. | Endocrinology 20060501 |
| Apoptotic effects of 25-hydroxycholesterol in immature rat Sertoli cells: prevention by 17beta-estradiol. | Reproductive toxicology (Elmsford, N.Y.) 20060401 |
| Contributions of autophagic and apoptotic mechanisms to CrTX-induced death of K562 cells. | Toxicon : official journal of the International Society on Toxinology 20060401 |
| Design, synthesis, and biological evaluation of isoquinoline-1,3,4-trione derivatives as potent caspase-3 inhibitors. | Journal of medicinal chemistry 20060309 |
| Enhanced cystatin C and lysosomal protease expression following 6-hydroxydopamine exposure. | Neurotoxicology 20060301 |
| Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases. | Cancer letters 20060208 |
| Ce(4+) induced down-regulation of ERK-like MAPK and activation of nucleases during the apoptosis of cultured Taxus cuspidata cells. | Journal of inorganic biochemistry 20060201 |
| Glutamate-induced oxidative stress, but not cell death, is largely dependent upon extracellular calcium in mouse neuronal HT22 cells. | Neuroscience letters 20060130 |
| Tetrandrine-induced apoptosis in rat primary hepatocytes is initiated from mitochondria: caspases and endonuclease G (Endo G) pathway. | Toxicology 20060120 |
| R(+)-methanandamide elicits a cyclooxygenase-2-dependent mitochondrial apoptosis signaling pathway in human neuroglioma cells. | Pharmaceutical research 20060101 |
| HSP90 protects apoptotic cleavage of vimentin in geldanamycin-induced apoptosis. | Molecular and cellular biochemistry 20060101 |
| Pharmacological activity in growth inhibition and apoptosis of cultured human leiomyomal cells of tropical plant Scutellaria barbata D. Don (Lamiaceae). | Environmental toxicology and pharmacology 20060101 |
| Mechanisms of induction of apoptosis by anthraquinone anticancer drugs aclarubicin and mitoxantrone in comparison with doxorubicin: relation to drug cytotoxicity and caspase-3 activation. | Apoptosis : an international journal on programmed cell death 20051201 |
| Amplification loop cascade for increasing caspase activity induced by docetaxel. | Journal of cellular biochemistry 20051101 |
| Butyrate-induced proapoptotic and antiangiogenic pathways in EAT cells require activation of CAD and downregulation of VEGF. | Biochemical and biophysical research communications 20051007 |
| Glycine- and proline-rich glycoprotein isolated from Solanum nigrum Linne activates caspase-3 through cytochrome c in HT-29 cells. | Oncology reports 20050901 |
| Using peptidic inhibitors to systematically probe the S1' site of caspase-3 and caspase-7. | Organic letters 20050804 |
| Molecular mechanism of ursolic acid induced apoptosis in poorly differentiated endometrial cancer HEC108 cells. | Oncology reports 20050801 |
| Glycyrrhizin induces apoptosis in human stomach cancer KATO III and human promyelotic leukemia HL-60 cells. | International journal of molecular medicine 20050801 |
| Atiprimod blocks STAT3 phosphorylation and induces apoptosis in multiple myeloma cells. | British journal of cancer 20050711 |
| Scopoletin induces apoptosis in human promyeloleukemic cells, accompanied by activations of nuclear factor kappaB and caspase-3. | Life sciences 20050701 |
| Signal role for activation of caspase-3-like protease and burst of superoxide anions during Ce4+-induced apoptosis of cultured Taxus cuspidata cells. | Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20050601 |
| [Characteristics of N-methyl-N-nitrosourea-induced retinal degeneration in animals and application for the therapy of human retinitis pigmentosa]. | Nippon Ganka Gakkai zasshi 20050601 |
| Influence of caspase activity on micronuclei detection: a possible role for caspase-3 in micronucleation. | Mutagenesis 20050501 |
| [The treatment of retinal apoptosis by Caspase 3 inhibitor Ac-DEVD-CHO in experimental myopia]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20050501 |
| Mechanism of inhibition of ascites tumor growth in mice by curcumin is mediated by NF-kB and caspase activated DNase. | Molecular and cellular biochemistry 20050501 |
| Sepsis stimulates calpain activity in skeletal muscle by decreasing calpastatin activity but does not activate caspase-3. | American journal of physiology. Regulatory, integrative and comparative physiology 20050301 |
| Mechanism of ricin-induced apoptosis in human cervical cancer cells. | Biochemical pharmacology 20050301 |
| PI3K/AKT is involved in mediating survival signals that rescue Ewing tumour cells from fibroblast growth factor 2-induced cell death. | British journal of cancer 20050227 |
| Interaction between gemcitabine and topotecan in human non-small-cell lung cancer cells: effects on cell survival, cell cycle and pharmacogenetic profile. | British journal of cancer 20050227 |
| Molecular mechanisms of apoptosis induced by Scorpio water extract in human hepatoma HepG2 cells. | World journal of gastroenterology 20050221 |
| Caprine herpesvirus-1 (CapHV-1) induces apoptosis in goat peripheral blood mononuclear cells. | Veterinary immunology and immunopathology 20050210 |
| Failure of caspase inhibition in the double-lesion rat model of striatonigral degeneration (multiple system atrophy). | Acta neuropathologica 20050201 |
| Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells. | Cancer letters 20050131 |
| Ursolic acid induces Bax-dependent apoptosis through the caspase-3 pathway in endometrial cancer SNG-II cells. | Oncology reports 20050101 |
| Mechanisms underlying the growth inhibitory effects of the cyclo-oxygenase-2 inhibitor celecoxib in human breast cancer cells. | Breast cancer research : BCR 20050101 |
| Runx-dependent expression of PKC is critical for cell survival in the sea urchin embryo. | BMC biology 20050101 |
| Hydrogen sulfide-induced apoptosis of human aorta smooth muscle cells via the activation of mitogen-activated protein kinases and caspase-3. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041101 |
| Capsaicin-induced apoptosis and reduced release of reactive oxygen species in MBT-2 murine bladder tumor cells. | Archives of pharmacal research 20041101 |
| Differential effects of caspase inhibitors on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney. | European journal of pharmacology 20041025 |
| Clinical and experimental study of oxaliplatin in treating human gastric carcinoma. | World journal of gastroenterology 20041001 |
| Oligonucleosome DNA fragmentation of caspase 3 deficient MCF-7 cells in palmitate-induced apoptosis. | Nucleosides, nucleotides & nucleic acids 20041001 |
| Protease-triggered photosensitizing beacon based on singlet oxygen quenching and activation. | Journal of the American Chemical Society 20040922 |
| Inhibition of poly (ADP-ribose) polymerase and caspase-3, but not caspase-1, prevents apoptosis and improves spatial memory of rats with twice-repeated cerebral ischemia. | Life sciences 20040903 |
| Anticancer agents are potent neurotoxins in vitro and in vivo. | Annals of neurology 20040901 |
| Caspase-3-like protease influences but is not essential for DNA fragmentation in Blastocystis undergoing apoptosis. | European journal of cell biology 20040901 |
| Cytotoxic mechanisms by M239V presenilin 2, a little-analyzed Alzheimer's disease-causative mutant. | Journal of neuroscience research 20040815 |
| Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation. | British journal of cancer 20040802 |
| Nonsteroidal anti-inflammatory drugs potentiate 1-methyl-4-phenylpyridinium (MPP+)-induced cell death by promoting the intracellular accumulation of MPP+ in PC12 cells. | The Journal of pharmacology and experimental therapeutics 20040801 |
| The transmembrane domain of hepatitis C virus E1 glycoprotein induces cell death. | Virus research 20040801 |
| 1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a Parkinsonism-inducing endogenous toxin, increases alpha-synuclein expression and causes nuclear damage in human dopaminergic cells. | Journal of neuroscience research 20040515 |
| Reducing the peptidyl features of caspase-3 inhibitors: a structural analysis. | Journal of medicinal chemistry 20040506 |
| Caspase inhibitors prevent endothelial apoptosis and cerebral vasospasm in dog model of experimental subarachnoid hemorrhage. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040401 |
| Activation of c-Jun N-terminal kinase is required for ultraviolet B-induced apoptosis of murine peritoneal macrophages in vitro. | Journal of photochemistry and photobiology. B, Biology 20040220 |
| Role of caspases-3 and -7 in Apaf-1 proteolytic cleavage and degradation events during cisplatin-induced apoptosis in melanoma cells. | Experimental cell research 20040215 |
| Discovery of novel aspartyl ketone dipeptides as potent and selective caspase-3 inhibitors. | Bioorganic & medicinal chemistry letters 20040209 |
| Rapid annexin-V labeling in synaptosomes. | Neurochemistry international 20040201 |
| GP7 can induce apoptotic DNA fragmentation of human leukemia cells through caspase-3-dependent and -independent pathways. | International journal of molecular medicine 20040101 |
| Mechanism of mahanine-induced apoptosis in human leukemia cells (HL-60). | Biochemical pharmacology 20040101 |
| A novel method for evaluation and screening of caspase inhibitory peptides by the amino acid positional fitness score. | BMC pharmacology 20040101 |
| Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression. | Arthritis research & therapy 20040101 |
| Cytoskeletal actin degradation induced by lovastatin in cardiomyocytes is mediated through caspase-2. | Cell biology international 20040101 |
| Role of mitochondria in neuron apoptosis during ischemia-reperfusion injury. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20040101 |
| Lovastatin-induced cardiac toxicity involves both oncotic and apoptotic cell death with the apoptotic component blunted by both caspase-2 and caspase-3 inhibitors. | Toxicology and applied pharmacology 20031215 |
| Oligonucleosomal DNA fragmentation in MCF-7 cells undergoing palmitate-induced apoptosis. | Biochemistry. Biokhimiia 20031201 |
| Cisplatin-induced apoptosis in melanoma cells: role of caspase-3 and caspase-7 in Apaf-1 proteolytic cleavage and in execution of the degradative phases. | Annals of the New York Academy of Sciences 20031201 |
| Interruption of nuclear factor kappaB signaling by the androgen receptor facilitates 12-O-tetradecanoylphorbolacetate-induced apoptosis in androgen-sensitive prostate cancer LNCaP cells. | Cancer research 20031101 |
| JNK/SAPK is required in nitric oxide-induced apoptosis in osteoblasts. | Archives of pharmacal research 20031101 |
| [Effect of tumor necrosis factor-alpha and interleukin-1beta on bovine pulmonary arterial endothelial cell apoptosis]. | Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20031101 |
| Involvement of nucleophosmin/B23 in TPA-induced megakaryocytic differentiation of K562 cells. | British journal of cancer 20031006 |
| Wortmannin-enhanced X-ray-induced apoptosis of human T-cell leukemia MOLT-4 cells possibly through the JNK/SAPK pathway. | Radiation research 20031001 |
| Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability. | The Journal of biological chemistry 20030912 |
| Ischemic preconditioning by caspase cleavage of poly(ADP-ribose) polymerase-1. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030903 |
| The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization. | The Journal of pharmacology and experimental therapeutics 20030901 |
| Mechanisms of sodium nitroprusside-induced death in human chondrocytes. | Rheumatology international 20030901 |
| Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells. | Blood 20030801 |
| Caspase-independent cell death by low concentrations of nitric oxide in PC12 cells: involvement of cytochrome C oxidase inhibition and the production of reactive oxygen species in mitochondria. | Journal of neuroscience research 20030801 |
| Enhancement of sensitivity to cisplatin by orobol is associated with increased mitochondrial cytochrome c release in human ovarian carcinoma cells. | Gynecologic oncology 20030801 |
| Caspase-mediated cleavage of JNK during stress-induced apoptosis. | Biochemical and biophysical research communications 20030711 |
| Nicotinyl aspartyl ketones as inhibitors of caspase-3. | Bioorganic & medicinal chemistry letters 20030707 |
| Proteasome inhibitors induce growth inhibition and apoptosis in myeloma cell lines and in human bone marrow myeloma cells irrespective of chromosome 13 deletion. | Journal of cancer research and clinical oncology 20030701 |
| Caspase-3 and its inhibitor Ac-DEVD-CHO in rat lens epithelial cell apoptosis induced by hydrogen in vitro. | Chinese medical journal 20030701 |
| beta-Phenylethyl isothiocyanate-mediated apoptosis in hepatoma HepG2 cells. | Cellular and molecular life sciences : CMLS 20030701 |
| Differential modulation of apoptosis-associated proteins by ethanol in rat cerebral cortex and cerebellum. | European journal of pharmacology 20030606 |
| Inhibition of caspases promotes long-term survival and reinnervation by axotomized spinal motoneurons of denervated muscle in newborn rats. | Experimental neurology 20030601 |
| High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501 |
| Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis. | Acta neuropathologica 20030501 |
| Activation of caspases-3/7 is dispensable for idarubicin-induced apoptotic DNA fragmentation in human leukemia cells. | International journal of oncology 20030501 |
| Protective effect of S-allyl-L-cysteine, a garlic compound, on amyloid beta-protein-induced cell death in nerve growth factor-differentiated PC12 cells. | Neuroscience research 20030501 |
| Herba houttuyniae extract induces apoptotic death of human promyelocytic leukemia cells via caspase activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release. | Experimental & molecular medicine 20030430 |
| Oxidative stress-induced cell death of human oral neutrophils. | American journal of physiology. Cell physiology 20030401 |
| Molecular dynamics studies of caspase-3. | Biophysical journal 20030401 |
| Expression of dominant-negative Fas-associated death domain blocks human keratinocyte apoptosis and vesication induced by sulfur mustard. | The Journal of biological chemistry 20030307 |
| Apoptosis of bladder cancer cells induced by short-term and low-dose Mitomycin-C: potential molecular mechanism and clinical implication. | International journal of molecular medicine 20030301 |
| Apoptotic cell death induction by F 11782 a novel dual catalytic inhibitor of topoisomerases I and II. | Biochemical pharmacology 20030301 |
| Caspase-mediated apoptosis in sponges: cloning and function of the phylogenetic oldest apoptotic proteases from Metazoa. | Biochimica et biophysica acta 20030217 |
| Roles of JNK-1 and p38 in selective induction of apoptosis by capsaicin in ras-transformed human breast epithelial cells. | International journal of cancer 20030210 |
| Mechanisms of glucocorticoid-induced Leydig cell apoptosis. | Molecular and cellular endocrinology 20030131 |
| Caspase-9 takes part in programmed cell death in developing mouse kidney. | Nephron. Experimental nephrology 20030101 |
| Interleukin-2 activated NK cells do not use the CD95L- and TRAIL-pathways in the rapid induction of apoptosis of rat colon carcinoma CC531s cells. | Immunobiology 20030101 |
| A common pathway for chemotherapy-induced apoptosis in human squamous cell carcinoma lines distinct from that of receptor-mediated cell death. | Anticancer research 20030101 |
| Delineation of signalling pathway leading to antioxidant-dependent inhibition of dexamethasone-mediated muscle cell death. | Journal of muscle research and cell motility 20030101 |
| Calpain and caspase-3 inhibitors reduce infarct size and post-ischemic apoptosis in rat heart without modifying contractile recovery. | Cellular and molecular biology (Noisy-le-Grand, France) 20030101 |
| Ordering ceramide-induced cell detachment and apoptosis in human neuroepithelioma. | Neuroscience letters 20021216 |
| Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production. | Biochemical pharmacology 20021215 |
| Purging effect of dibutyl phthalate on leukemia cells involves fas independent activation of caspase-3/CPP32 protease. | Cancer letters 20021205 |
| Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase. | Journal of cell science 20021201 |
| Time sequence analysis of caspase-3-independent programmed cell death and apoptosis in X-irradiated human leukemic MOLT-4 cells. | Cell and tissue research 20021201 |
| Caspase-3-dependent pathway mediates apoptosis of human mononuclear cells induced by cellulosic haemodialysis membranes. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021101 |
| Human secreted frizzled-related protein is down-regulated and induces apoptosis in human cervical cancer. | Experimental cell research 20021101 |
| Amylin-induced cytotoxicity is associated with activation of caspase-3 and MAP kinases. | Biological chemistry 20021101 |
| Phosphorylation of Fas-associated death domain contributes to enhancement of etoposide-induced apoptosis in prostate cancer cells. | Japanese journal of cancer research : Gann 20021001 |
| Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis. | The Journal of biological chemistry 20020913 |
| Caspase activation in etoposide-treated fibroblasts is correlated to ERK phosphorylation and both events are blocked by polyamine depletion. | FEBS letters 20020911 |
| Inhibitor specificity of recombinant and endogenous caspase-9. | The Biochemical journal 20020901 |
| Hydrogen peroxide induces apoptosis of osteocytes: involvement of calcium ion and caspase activity. | Calcified tissue international 20020901 |
| Nitric oxide interferes with salivary mucin synthesis: involvement of ERK and p38 mitogen-activated protein kinase. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20020901 |
| Avian encephalomyelitis virus induces apoptosis via major structural protein VP3. | Virology 20020815 |
| Bcl-2 blocks apoptosis caused by pierisin-1, a guanine-specific ADP-ribosylating toxin from the cabbage butterfly. | Biochemical and biophysical research communications 20020809 |
| Involvement of human heat shock protein 90 alpha in nicotine-induced apoptosis. | International journal of cancer 20020701 |
| Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation. | Human molecular genetics 20020615 |
| Cell death and mechanoprotection by filamin a in connective tissues after challenge by applied tensile forces. | The Journal of biological chemistry 20020614 |
| Inhibition of programmed cell death impairs in vitro vascular-like structure formation and reduces in vivo angiogenesis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020601 |
| Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1. | Archives of toxicology 20020601 |
| Caspase inhibition protects nerve terminals from in vitro degradation. | Neurochemical research 20020601 |
| The protection of hybridoma cells from apoptosis by caspase inhibition allows culture recovery when exposed to non-inducing conditions. | Journal of biotechnology 20020523 |
| Ca(2+)-independent caspase-3 but not Ca(2+)-dependent caspase-2 activation induced by oxidative stress leads to SH-SY5Y human neuroblastoma cell apoptosis. | Journal of neuroscience research 20020515 |
| Involvement of caspase and reactive oxygen species in cyanobacterial toxin anatoxin-a-induced cytotoxicity and apoptosis in rat thymocytes and Vero cells. | Archives of toxicology 20020501 |
| Apoptosis during ectromelia orthopoxvirus infection is DEVDase dependent: in vitro and in vivo studies. | Microbes and infection 20020501 |
| Inhibition of sodium butyrate-induced apoptosis in recombinant Chinese hamster ovary cells by constitutively expressing antisense RNA of caspase-3. | Biotechnology and bioengineering 20020420 |
| Proteolytic cleavage of cyclin E leads to inactivation of associated kinase activity and amplification of apoptosis in hematopoietic cells. | Molecular and cellular biology 20020401 |
| D4-GDI is cleaved by caspase-3 during daunorubicin-induced apoptosis in HL-60 cells. | Experimental & molecular medicine 20020331 |
| Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells. | Oncogene 20020327 |
| Involvement of caspase-3 and p38 mitogen-activated protein kinase in cobalt chloride-induced apoptosis in PC12 cells. | Journal of neuroscience research 20020315 |
| Neurotoxic mechanisms by Alzheimer's disease-linked N141I mutant presenilin 2. | The Journal of pharmacology and experimental therapeutics 20020301 |
| Kainic acid-induced neuronal cell death in cerebellar granule cells is not prevented by caspase inhibitors. | British journal of pharmacology 20020301 |
| Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301 |
| Caspase-3 inhibitor transiently delays inherited retinal degeneration in C3H mice carrying the rd gene. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20020301 |
| Caspase activation in equine influenza virus induced apoptotic cell death. | Veterinary microbiology 20020204 |
| Neurotoxic mechanisms triggered by Alzheimer's disease-linked mutant M146L presenilin 1: involvement of NO synthase via a novel pertussis toxin target. | Journal of neurochemistry 20020201 |
| Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease. | Biochemical pharmacology 20020115 |
| Characterization of cell death induced by vinflunine, the most recent Vinca alkaloid in clinical development. | British journal of cancer 20020107 |
| Role of caspase 3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2. | Molecular pharmacology 20020101 |
| Protein kinase C-eta regulates resistance to UV- and gamma-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation. | Neuro-oncology 20020101 |
| Anti-CD20 antibody (IDEC-C2B8, rituximab) enhances efficacy of cytotoxic drugs on neoplastic lymphocytes in vitro: role of cytokines, complement, and caspases. | Haematologica 20020101 |
| Blockade of maitotoxin-induced oncotic cell death reveals zeiosis. | BMC physiology 20020101 |
| The antimicrotubule drug estramustine but not irradiation induces apoptosis in malignant glioma involving AKT and caspase pathways. | Journal of neuro-oncology 20020101 |
| Lactacystin, a proteasome inhibitor, potentiates the apoptotic effect of parthenolide, an inhibitor of NFkappaB activation, on drug-resistant mouse leukemia L1210 cells. | Anticancer research 20020101 |
| Arsenic trioxide induces apoptosis in human T-cell leukemia virus type 1- and type 2-infected cells by a caspase-3-dependent mechanism involving Bcl-2 cleavage. | Blood 20011215 |
| Vibrio vulnificus cytolysin induces superoxide anion-initiated apoptotic signaling pathway in human ECV304 cells. | The Journal of biological chemistry 20011214 |
| Inhibition of caspase-3 improves contractile recovery of stunned myocardium, independent of apoptosis-inhibitory effects. | Journal of the American College of Cardiology 20011201 |
| Programmed cell death in mature erythrocytes: a model for investigating death effector pathways operating in the absence of mitochondria. | Cell death and differentiation 20011201 |
| Roles of caspases in the programmed cell death of motoneurons in vivo. | Archives of histology and cytology 20011201 |
| Involvement of TLCK-sensitive serine protease in colchicine-induced cell death of sympathetic neurons in culture. | Journal of neuroscience research 20011115 |
| Protein kinase C involvement in aloe-emodin- and emodin-induced apoptosis in lung carcinoma cell. | British journal of pharmacology 20011101 |
| Dlk/ZIP kinase-induced apoptosis in human medulloblastoma cells: requirement of the mitochondrial apoptosis pathway. | British journal of cancer 20011101 |
| Platelet-activating factor (PAF) enhances apoptosis induced by ultraviolet radiation in corneal epithelial cells through cytochrome c-caspase activation. | Current eye research 20011101 |
| Limited proteolysis of filamin is catalyzed by caspase-3 in U937 and Jurkat cells. | Journal of biochemistry 20011001 |
| Apaf-1 overexpression partially overcomes apoptotic resistance in a cisplatin-selected HeLa cell line. | FEBS letters 20010914 |
| Fas-mediated apoptosis in a rat acinar cell line is dependent on caspase-1 activity. | Cellular signalling 20010901 |
| Attenuation of staurosporine-induced apoptosis, oxidative stress, and mitochondrial dysfunction by synthetic superoxide dismutase and catalase mimetics, in cultured cortical neurons. | Experimental neurology 20010901 |
| Cleavage of Fyn and Lyn in their N-terminal unique regions during induction of apoptosis: a new mechanism for Src kinase regulation. | Oncogene 20010816 |
| p53 activates the mitochondrial death pathway and apoptosis of ventricular myocytes independent of de novo gene transcription. | Journal of molecular and cellular cardiology 20010801 |
| Infection with Langat Flavivirus or expression of the envelope protein induces apoptotic cell death. | Virology 20010801 |
| Caspase activity is involved in, but is dispensable for, early motoneuron death in the chick embryo cervical spinal cord. | Molecular and cellular neurosciences 20010801 |
| Caspase-3-mediated cleavage of the NF-kappa B subunit p65 at the NH2 terminus potentiates naphthoquinone analog-induced apoptosis. | The Journal of biological chemistry 20010706 |
| Cocaine-mediated apoptosis in bovine coronary artery endothelial cells: role of nitric oxide. | The Journal of pharmacology and experimental therapeutics 20010701 |
| Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis. | Journal of neuroscience research 20010701 |
| [Aminopeptidase inhibitor Bestatin induces HL-60 cell apoptosis through activating caspase 3]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20010701 |
| Caspase-3 is actively involved in okadaic acid-induced lens epithelial cell apoptosis. | Experimental cell research 20010610 |
| Caspase activity in newt spermatogonial apoptosis induced by prolactin and cycloheximide. | Molecular reproduction and development 20010601 |
| Time course of the apoptotic cascade and effects of caspase inhibitors in adult rat ventricular cardiomyocytes. | Journal of molecular and cellular cardiology 20010501 |
| Sodium nitroprusside induces apoptosis of H9C2 cardiac muscle cells in a c-Jun N-terminal kinase-dependent manner. | International immunopharmacology 20010501 |
| Quinacrine induces cytochrome c-dependent apoptotic signaling in human cervical carcinoma cells. | Archives of pharmacal research 20010401 |
| Caspase inhibitors promote the survival of avulsed spinal motoneurons in neonatal rats. | Neuroreport 20010305 |
| Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: relevance to therapeutical application for Parkinson's disease. | Journal of neuroscience research 20010301 |
| Virus infection induces proteolytic processing of IL-18 in human macrophages via caspase-1 and caspase-3 activation. | European journal of immunology 20010301 |
| Initiation of apoptosis by actin cytoskeletal derangement in human airway epithelial cells. | American journal of respiratory cell and molecular biology 20010301 |
| Caspase-dependent cleavage of cadherins and catenins during osteoblast apoptosis. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010301 |
| Homology modeling of nematode Caenorhabditis elegans CED3 protein-inhibitor complex. | Biochemical and biophysical research communications 20010216 |
| Insulin-like growth factor-I and Bcl-X(L) inhibit c-jun N-terminal kinase activation and rescue Schwann cells from apoptosis. | Journal of neurochemistry 20010201 |
| Effects of a novel hepatoprotective drug, ZNC-2381, on fas-induced hepatocellular caspase-3 activity and apoptosis in mice. | Pharmacology 20010201 |
| Growth inhibition and apoptosis of gastric cancer cell lines by Anemarrhena asphodeloides Bunge. | Journal of gastroenterology 20010201 |
| [Induction of apoptosis of splenic lymphocytes in mice by accelerated carbon ions]. | Canadian journal of physiology and pharmacology 20010201 |
| Caspase-3-mediated processing of poly(ADP-ribose) glycohydrolase during apoptosis. | The Journal of biological chemistry 20010126 |
| Design and synthesis of rhodamine 110 derivative and caspase-3 substrate for enzyme and cell-based fluorescent assay. | Bioorganic & medicinal chemistry letters 20010108 |
| Reactive oxygen species and caspase activation mediate silica-induced apoptosis in alveolar macrophages. | American journal of physiology. Lung cellular and molecular physiology 20010101 |
| DNA-dependent protein kinase catalytic subunit is cleaved during UV-induced apoptosis. | Journal of dermatological science 20010101 |
| Increased sensitivity to sodium salicylate-induced apoptosis in drug-resistant leukemia L1210 cells. | Anticancer research 20010101 |
| Deciphering the plasma membrane hallmarks of apoptotic cells: phosphatidylserine transverse redistribution and calcium entry. | BMC cell biology 20010101 |
| Inhibitors of caspase homologues suppress an apoptotic phenotype in cultured rabbit corpora lutea. | Reproduction, fertility, and development 20010101 |
| New concepts in radiation-induced apoptosis: 'premitotic apoptosis' and 'postmitotic apoptosis'. | Journal of cellular and molecular medicine 20010101 |
| The neuroprotective effect of pituitary adenylate cyclase-activating polypeptide on cerebellar granule cells is mediated through inhibition of the CED3-related cysteine protease caspase-3/CPP32. | Proceedings of the National Academy of Sciences of the United States of America 20001121 |
| Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells. | Cancer research 20001101 |
| Organophosphorus compound-induced apoptosis in SH-SY5Y human neuroblastoma cells. | Toxicology and applied pharmacology 20001015 |
| Different mechanisms between premitotic apoptosis and postmitotic apoptosis in X-irradiated U937 cells. | International journal of radiation oncology, biology, physics 20000601 |
| Paclitaxel-induced apoptosis in non-small cell lung cancer cell lines is associated with increased caspase-3 activity. | The Journal of thoracic and cardiovascular surgery 20000401 |
| Induction of apoptosis by the O-hydroxyethyl-D(Ser)(8)-cyclosporine A derivative SDZ IMM 125 in rat hepatocytes. | The Journal of pharmacology and experimental therapeutics 20000401 |
| Cocaine induces apoptosis in human coronary artery endothelial cells. | Journal of cardiovascular pharmacology 20000401 |
| Cocaine induces apoptosis in fetal myocardial cells through a mitochondria-dependent pathway. | The Journal of pharmacology and experimental therapeutics 20000101 |
| Involvement of activated caspase-3-like proteases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons. | Journal of neurochemistry 20000101 |
| The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons. | Journal of neurochemistry 20000101 |
| Glutathione oxidation and mitochondrial depolarization as mechanisms of nordihydroguaiaretic acid-induced apoptosis in lipoxygenase-deficient FL5.12 cells. | Toxicological sciences : an official journal of the Society of Toxicology 20000101 |
| Effect of heat stress on serotonin-2A receptor-mediated intracellular calcium mobilization in rat C6 glioma cells. | Journal of neural transmission (Vienna, Austria : 1996) 20000101 |
| Prevention of cycloheximide-induced apoptosis in hepatocytes by adenosine and by caspase inhibitors. | Biochemical pharmacology 19991215 |
| The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells. | Cancer research 19991101 |
| Apoptosis induced by vitamin D compounds in breast cancer cells is inhibited by Bcl-2 but does not involve known caspases or p53. | Cancer research 19991001 |
| Effects of BAPTA-AM and forskolin on apoptosis and cytochrome c release in photosensitized Chinese hamster V79 cells. | Photochemistry and photobiology 19991001 |
| Induction of apoptosis by penta-O-galloyl-beta-D-glucose through activation of caspase-3 in human leukemia HL-60 cells. | European journal of pharmacology 19990924 |
| Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19990815 |
| Activation of neuronal caspase-3 by intracellular accumulation of wild-type Alzheimer amyloid precursor protein. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19990815 |
| Cleavage and relocation of the tyrosine kinase P59FYN during Fas-mediated apoptosis in T lymphocytes. | Oncogene 19990708 |
| A predominant apoptotic death pathway of neuronal PC12 cells induced by activated microglia is displaced by a non-apoptotic death pathway following blockage of caspase-3-dependent cascade. | The Journal of biological chemistry 19990528 |
| Caspase-3 activation during apoptosis caused by glutathione-doxorubicin conjugate. | British journal of cancer 19990501 |
| Ceramide generation in nitric oxide-induced apoptosis. Activation of magnesium-dependent neutral sphingomyelinase via caspase-3. | The Journal of biological chemistry 19990409 |
| Induction of apoptosis and changes in nuclear G-actin are mediated by different pathways: the effect of inhibitors of protein and RNA synthesis in isolated rat hepatocytes. | Toxicology and applied pharmacology 19990401 |
| Caspase-dependent activation of calpain during drug-induced apoptosis. | The Journal of biological chemistry 19990319 |
| Induction of apoptosis by hinokitiol, a potent iron chelator, in teratocarcinoma F9 cells is mediated through the activation of caspase-3. | Cell proliferation 19990201 |
| Menadione-induced apoptosis and the degradation of lamin-like proteins in tobacco protoplasts. | Cellular and molecular life sciences : CMLS 19990201 |
| Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation. | Free radical research 19990101 |
| Evidence that non-caspase proteases are required for chromatin degradation during apoptosis. | Cell death and differentiation 19981201 |
| Investigation of glucocorticoid-induced apoptotic pathway: processing of caspase-6 but not caspase-3. | Cell death and differentiation 19981201 |
| Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19981015 |
| Involvement of caspase-like proteinases in apoptosis of neuronal PC12 cells and primary cultured microglia induced by 6-hydroxydopamine. | Journal of neuroscience research 19981015 |
| Caspase-3-like activity is necessary for IL-2 release in activated Jurkat T-cells. | Experimental cell research 19981010 |
| Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide. | Cell death and differentiation 19981001 |
| Proteolytic activation of PKN by caspase-3 or related protease during apoptosis. | Proceedings of the National Academy of Sciences of the United States of America 19980929 |
| Granulysin-induced apoptosis. I. Involvement of at least two distinct pathways. | Journal of immunology (Baltimore, Md. : 1950) 19980815 |
| Distinct steps in DNA fragmentation pathway during camptothecin-induced apoptosis involved caspase-, benzyloxycarbonyl- and N-tosyl-L-phenylalanylchloromethyl ketone-sensitive activities. | Cancer research 19980715 |
| Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19980615 |
| Dissection of pathways leading to antigen receptor-induced and Fas/CD95-induced apoptosis in human B cells. | Journal of immunology (Baltimore, Md. : 1950) 19980615 |
| Fas-mediated apoptosis in mouse hepatocytes involves the processing and activation of caspases. | Hepatology (Baltimore, Md.) 19980601 |
| Nitric oxide-dependent production of cGMP supports the survival of rat embryonic motor neurons cultured with brain-derived neurotrophic factor. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19980515 |
| The intracellular domain of p55 tumor necrosis factor receptor induces apoptosis which requires different caspases in naive and neuronal PC12 cells. | Journal of neuroscience research 19980515 |
| Induction of apoptosis and activation of interleukin 1beta-converting enzyme/Ced-3 protease (caspase-3) and c-Jun NH2-terminal kinase 1 by benzo(a)pyrene. | Cancer research 19980515 |
| Proteolytic cleavage of HsRad51 during apoptosis. | FEBS letters 19980508 |
| Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease. | The American journal of physiology 19980401 |
| Preparation and imaging of nuclear spreads from cells of the zebrafish embryo. Evidence for large degradation intermediates in apoptosis. | Chromosoma 19980301 |
| Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. | Cancer research 19980201 |
| Apoptotic cell death and CPP32-like activation induced by thapsigargin and their prevention by nerve growth factor in PC12 cells. | Biochimica et biophysica acta 19980102 |
| Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. | The Journal of biological chemistry 19971205 |
| Cooperative interception of neuronal apoptosis by BCL-2 and BAG-1 expression: prevention of caspase activation and reduced production of reactive oxygen species. | Journal of neurochemistry 19971101 |
| Need for caspases in apoptosis of trophic factor-deprived PC12 cells. | Journal of neuroscience research 19971001 |
| Activation of caspase-2 in apoptosis. | The Journal of biological chemistry 19970822 |
| Role of caspases (ICE/CED 3 proteases) in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A. | Kidney international 19970801 |
| Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis. | Proceedings of the National Academy of Sciences of the United States of America 19970513 |
| Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases. | The Journal of biological chemistry 19970314 |
| Inhibition of CPP32-like proteases prevents granzyme B- and Fas-, but not granzyme A-based cytotoxicity exerted by CTL clones. | Journal of immunology (Baltimore, Md. : 1950) 19970301 |
| Rapid loss in the mitochondrial membrane potential during geranylgeranoic acid-induced apoptosis. | Biochemical and biophysical research communications 19970103 |
| Specific cleavage of alpha-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease. | The Journal of biological chemistry 19961206 |
| Involvement of CPP32/Yama-like protease in CPT-11-induced death signal transduction pathway. | Toxicology in vitro : an international journal published in association with BIBRA 19961201 |
| Intracellular IL-1beta is an inhibitor of Fas-mediated apoptosis. | Journal of immunology (Baltimore, Md. : 1950) 19961101 |