Altered expression and activities of enzymes involved in thiamine diphosphate biosynthesis in Saccharomyces cerevisiae under oxidative and osmotic stress.

FEMS yeast research 20120801

Decarboxylation mechanisms in biological system.

Bioorganic chemistry 20120801

A high-affinity and specific carrier-mediated mechanism for uptake of thiamine pyrophosphate by human colonic epithelial cells.

American journal of physiology. Gastrointestinal and liver physiology 20120801

Computer-assisted study on the reaction between pyruvate and ylide in the pathway leading to lactyl-ThDP.

Journal of computer-aided molecular design 20120801

Identification of mitochondrial thiamin diphosphate carriers from Arabidopsis and maize.

Functional & integrative genomics 20120601

Crystal structure of a ring-cleaving cyclohexane-1,2-dione hydrolase, a novel member of the thiamine diphosphate enzyme family.

The FEBS journal 20120401

Bifunctionality of the thiamin diphosphate cofactor: assignment of tautomeric/ionization states of the 4'-aminopyrimidine ring when various intermediates occupy the active sites during the catalysis of yeast pyruvate decarboxylase.

Journal of the American Chemical Society 20120227

Effects of free Ca²⁺ on kinetic characteristics of holotransketolase.

The protein journal 20120201

kinITC: a new method for obtaining joint thermodynamic and kinetic data by isothermal titration calorimetry.

Journal of the American Chemical Society 20120111

Thiamine diphosphate in whole blood, thiamine and thiamine monophosphate in breast-milk in a refugee population.

PloS one 20120101

Altered heavy metals and transketolase found in autistic spectrum disorder.

Biological trace element research 20111201

Role of thiamine in Alzheimer's disease.

American journal of Alzheimer's disease and other dementias 20111201

Density-functional study on the equilibria in the ThDP activation.

Journal of molecular modeling 20111101

Thiamine supplementation in the critically ill.

Current opinion in clinical nutrition and metabolic care 20111101

Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase.

Nature 20111027

Cell damage through pentose phosphate pathway in fetus fibroblast cells exposed to methyl mercury.

Journal of applied toxicology : JAT 20111001

Role of thiamine pyrophosphate in oligomerisation, functioning and import of peroxisomal 2-hydroxyacyl-CoA lyase.

Biochimica et biophysica acta 20111001

Enzymatic probing analysis of an engineered riboswitch reveals multiple off conformations.

Nucleosides, nucleotides & nucleic acids 20110901

The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase.

Rejuvenation research 20110801

Acetyl-CoA metabolism in amprolium-evoked thiamine pyrophosphate deficits in cholinergic SN56 neuroblastoma cells.

Neurochemistry international 20110801

Characterization of a thiamin diphosphate-dependent phenylpyruvate decarboxylase from Saccharomyces cerevisiae.

The FEBS journal 20110601

Tomato LeTHIC is an Fe-requiring HMP-P synthase involved in thiamine synthesis and regulated by multiple factors.

Plant & cell physiology 20110601

Chronic alcoholism in rats induces a compensatory response, preserving brain thiamine diphosphate, but the brain 2-oxo acid dehydrogenases are inactivated despite unchanged coenzyme levels.

Journal of neurochemistry 20110601

Preliminary X-ray crystallographic studies of the catalytic subunit of Escherichia coli AHAS II with its cofactors.

Acta crystallographica. Section F, Structural biology and crystallization communications 20110601

Could thiamine pyrophosphate be a regulator of the nitric oxide synthesis in the endothelial cell of diabetic patients?

Medical hypotheses 20110501

Construction of a thiamine pyrophosphate high-producing strain of Aspergillus oryzae by overexpression of three genes involved in thiamine biosynthesis.

Journal of bioscience and bioengineering 20110401

Thermodynamic examination of the pyrophosphate sensor helix in the thiamine pyrophosphate riboswitch.

RNA (New York, N.Y.) 20110401

Identification of novel ligands for thiamine pyrophosphate (TPP) riboswitches.

Biochemical Society transactions 20110401

Thiamine (vitamin B1) concentrations in a population of Australians with alcohol use disorders are remarkably elevated.

The Medical journal of Australia 20110307

Solid-state NMR and density functional theory studies of ionization states of thiamin.

The journal of physical chemistry. B 20110203

RNA networks in prokaryotes I: CRISPRs and riboswitches.

Advances in experimental medicine and biology 20110101

[Measurement of thiamine concentration in the cat using high pressure liquid chromatography].

Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere 20110101

Modifications of a calcium phosphate cement with biomolecules--influence on nanostructure, material, and biological properties.

Journal of biomedical materials research. Part A 20101201

Functional nonequivalence of transketolase active centers.

IUBMB life 20101101

Crystal structures of phosphoketolase: thiamine diphosphate-dependent dehydration mechanism.

The Journal of biological chemistry 20101029

A general approach to the construction of structure-switching reporters from RNA aptamers.

Angewandte Chemie (International ed. in English) 20101018

Crystal structure of Bifidobacterium Longum phosphoketolase; key enzyme for glucose metabolism in Bifidobacterium.

FEBS letters 20100924

Double duty for a conserved glutamate in pyruvate decarboxylase: evidence of the participation in stereoelectronically controlled decarboxylation and in protonation of the nascent carbanion/enamine intermediate .

Biochemistry 20100921

Inhibition of transketolase by hexacyanoferrate(III).

Biochemistry. Biokhimiia 20100801

Molecular and biochemical characterization of folate transport proteins in retinal Müller cells.

Investigative ophthalmology & visual science 20100601

New insights into structure-function relationships of oxalyl CoA decarboxylase from Escherichia coli.

The FEBS journal 20100601

Computational study on the carboligation reaction of acetohidroxyacid synthase: new approach on the role of the HEThDP- intermediate.

Proteins 20100515

Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a 'direct pathway' between the 4'-aminopyrimidine N1' atoms.

The Journal of biological chemistry 20100409

Succinylphosphonate esters are competitive inhibitors of MenD that show active-site discrimination between homologous alpha-ketoglutarate-decarboxylating enzymes.

Biochemistry 20100330

The biochemical properties of the mitochondrial thiamine pyrophosphate carrier from Drosophila melanogaster.

The FEBS journal 20100301

The ligand-free state of the TPP riboswitch: a partially folded RNA structure.

Journal of molecular biology 20100212

Early metabolic reactivation versus antioxidant therapy after a traumatic spinal cord injury in adult rats.

Neuropathology : official journal of the Japanese Society of Neuropathology 20100201

Understanding the mode of action of ThDP in benzoylformate decarboxylase.

Biopolymers 20100101

Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch.

RNA (New York, N.Y.) 20100101

Energy minimization methods applied to riboswitches: a perspective and challenges.

RNA biology 20100101

The Thiamine diphosphate dependent Enzyme Engineering Database: a tool for the systematic analysis of sequence and structure relations.

BMC biochemistry 20100101

Biomarkers for detecting thiamine deficiency--improving confidence and taking a comprehensive history are also important.

Alcohol and alcoholism (Oxford, Oxfordshire) 20100101

[Existence of two different active sites on thiamine binding protein in plasma membranes of synaptosomes].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20100101

Characterization of acetohydroxyacid synthase I from Escherichia coli K-12 and identification of its inhibitors.

Bioscience, biotechnology, and biochemistry 20100101

Analysis of riboswitch structure and function by an energy landscape framework.

Journal of molecular biology 20091106

Structural and functional analysis of Vitamin K2 synthesis protein MenD.

Biochemical and biophysical research communications 20091030

Simultaneous determination of thiamine and its phosphate esters by a liquid chromatographic method based on post-column photolysis and chemiluminescence detection.

Journal of pharmaceutical and biomedical analysis 20091015

Deleterious versus neuroprotective effect of metabolic inhibition after traumatic spinal cord injury.

Spinal cord 20091001

Effects of vitamin B1 (thiamine) deficiency in lake trout (Salvelinus namaycush) alevins at hatching stage.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20091001

Mechanism-guided library design and dual genetic selection of synthetic OFF riboswitches.

Chembiochem : a European journal of chemical biology 20090921

Protein families reflect the metabolic diversity of organisms and provide support for functional prediction.

Physiological genomics 20090807

Determination of thiamin diphosphate in whole blood samples by high-performance liquid chromatography--a method suitable for pediatric diagnostics.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090701

Thiaminylated adenine nucleotides. Chemical synthesis, structural characterization and natural occurrence.

The FEBS journal 20090601

Thiamin diphosphate in biological chemistry: applications in biocatalysis, coenzyme analogues as mechanistic probes and natural derivatives of thiamin.

The FEBS journal 20090601

Thiamin diphosphate in biological chemistry: exploitation of diverse thiamin diphosphate-dependent enzymes for asymmetric chemoenzymatic synthesis.

The FEBS journal 20090601

Thiamin diphosphate in biological chemistry: analogues of thiamin diphosphate in studies of enzymes and riboswitches.

The FEBS journal 20090601

Thiamin diphosphate in biological chemistry: new aspects of thiamin metabolism, especially triphosphate derivatives acting other than as cofactors.

The FEBS journal 20090601

Inhibition of branched-chain alpha-ketoacid dehydrogenase kinase by thiamine pyrophosphate at different potassium ionic levels.

Bioscience, biotechnology, and biochemistry 20090501

Reaction mechanisms of thiamin diphosphate enzymes.

The FEBS journal 20090501

Reaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps.

The FEBS journal 20090501

Reaction mechanisms of thiamin diphosphate enzymes: new insights into the role of a conserved glutamate residue.

The FEBS journal 20090501

Reaction mechanisms of thiamin diphosphate enzymes: redox reactions.

The FEBS journal 20090501

Construction of a synthetic YdbK-dependent pyruvate:H2 pathway in Escherichia coli BL21(DE3).

Metabolic engineering 20090501

Transketolase: observations in alcohol-related brain damage research.

The international journal of biochemistry & cell biology 20090401

Enzymes that control the thiamine diphosphate pool in plant tissues. Properties of thiamine pyrophosphokinase and thiamine-(di)phosphate phosphatase purified from Zea mays seedlings.

Plant physiology and biochemistry : PPB 20090401

Carboxylesterase activity, cDNA sequence, and gene expression in malathion susceptible and resistant strains of the cotton aphid, Aphis gossypii.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20090301

Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase.

The FEBS journal 20090301

New function of the amino group of thiamine diphosphate in thiamine catalysis.

Biochemistry. Biokhimiia 20090301

Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase.

Biochemistry 20090210

Artificial ribozyme switches containing natural riboswitch aptamer domains.

Angewandte Chemie (International ed. in English) 20090101

Propioin synthesis using thiamine diphosphate-dependent enzymes.

Biotechnology progress 20090101

Predicting riboswitch regulation on a genomic scale.

Methods in molecular biology (Clifton, N.J.) 20090101

Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops.

Structure (London, England : 1993) 20081210

Chitosan-thiamine pyrophosphate as a novel carrier for siRNA delivery.

Pharmaceutical research 20081201

Catalyzing separation of carbon dioxide in thiamin diphosphate-promoted decarboxylation.

The FEBS journal 20081201

Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.

Acta crystallographica. Section D, Biological crystallography 20081101

Synthesis and biological evaluation of pyrophosphate mimics of thiamine pyrophosphate based on a triazole scaffold.

Organic & biomolecular chemistry 20081007

Switching the light on plant riboswitches.

Trends in plant science 20081001

Probing the active center of benzaldehyde lyase with substitutions and the pseudosubstrate analogue benzoylphosphonic acid methyl ester.

Biochemistry 20080722

Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch.

Journal of the American Chemical Society 20080702

Riboswitch effectors as protein enzyme cofactors.

RNA (New York, N.Y.) 20080601

Thiamin diphosphate catalysis: enzymic and nonenzymic covalent intermediates.

Chemical reviews 20080601

Changes in ECG and enzyme activity in rat heart after myocardial infarction: effect of TPP and MnCl2.

Journal of physiology and biochemistry 20080601

Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins.

Proteins 20080501

A DFT study of solvation effects on the tautomeric equilibrium and catalytic ylide generation of thiamin models.

Journal of computational chemistry 20080501

Rapid HPLC measurement of thiamine and its phosphate esters in whole blood.

Clinical chemistry 20080501

Mechanism of benzaldehyde lyase studied via thiamin diphosphate-bound intermediates and kinetic isotope effects.

Biochemistry 20080325

The evidence that the DNC (SLC25A19) is not the mitochondrial deoxyribonucleotide carrier.

Mitochondrion 20080301

Amino acids allosterically regulate the thiamine diphosphate-dependent alpha-keto acid decarboxylase from Mycobacterium tuberculosis.

The Journal of biological chemistry 20080227

Rational protein design of ThDP-dependent enzymes-engineering stereoselectivity.

Chembiochem : a European journal of chemical biology 20080215

Structural similarities between thiamin-binding protein and thiaminase-I suggest a common ancestor.

Biochemistry 20080205

Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides.

Biological chemistry 20080201

Molecular basis of gene regulation by the THI-box riboswitch.

Molecular microbiology 20080201

The mechanism of carrier-mediated transport of folates in BeWo cells: the involvement of heme carrier protein 1 in placental folate transport.

Bioscience, biotechnology, and biochemistry 20080201

Pyruvate dehydrogenase deficiency presenting as intermittent isolated acute ataxia.

Neuropediatrics 20080201

Evolutionary analysis of the TPP-dependent enzyme family.

Journal of molecular evolution 20080101

Thiamin phosphates in egg yolk granules and plasma of regular and embryonated eggs of hens and in five- and seven-day-old embryos.

Poultry science 20080101

The genes and enzymes involved in the biosynthesis of thiamin and thiamin diphosphate in yeasts.

Cellular & molecular biology letters 20080101

Structural characterization of CA1462, the Candida albicans thiamine pyrophosphokinase.

BMC structural biology 20080101

The preparation of site-specifically modified riboswitch domains as an example for enzymatic ligation of chemically synthesized RNA fragments.

Nature protocols 20080101

Effect of thiamine pyrophosphate on levels of serum lactate, maximum oxygen consumption and heart rate in athletes performing aerobic activity.

The Journal of international medical research 20080101

[Thiamine metabolism disorders in the rat brain in experimental alcoholism and a possibility of their correction by vitamin E].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20080101

Observation of an acryloyl-thiamin diphosphate adduct in the first step of clavulanic acid biosynthesis.

Journal of the American Chemical Society 20071226

Thiamine diphosphate binds to intermediates in the assembly of adenovirus fiber knob trimers in Escherichia coli.

Protein science : a publication of the Protein Society 20071201

Structure of the branched-chain keto acid decarboxylase (KdcA) from Lactococcus lactis provides insights into the structural basis for the chemoselective and enantioselective carboligation reaction.

Acta crystallographica. Section D, Biological crystallography 20071201

Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase.

The Journal of biological chemistry 20071130

Riboswitch-dependent gene regulation and its evolution in the plant kingdom.

Genes & development 20071115

Reengineering a natural riboswitch by dual genetic selection.

Journal of the American Chemical Society 20071114

Riboswitch control of gene expression in plants by splicing and alternative 3' end processing of mRNAs.

The Plant cell 20071101

The structures of pyruvate oxidase from Aerococcus viridans with cofactors and with a reaction intermediate reveal the flexibility of the active-site tunnel for catalysis.

Acta crystallographica. Section F, Structural biology and crystallization communications 20071101

Reactions of fac-[Re(CO)3(H2O)3]+ with nucleoside diphosphates and thiamine diphosphate in aqueous solution investigated by multinuclear NMR spectroscopy.

Inorganic chemistry 20071029

High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease.

Diabetologia 20071001

Elucidation of the chemistry of enzyme-bound thiamin diphosphate prior to substrate binding: defining internal equilibria among tautomeric and ionization states.

Biochemistry 20070918

Structure of the ThDP-dependent enzyme benzaldehyde lyase refined to 1.65 A resolution.

Acta crystallographica. Section F, Structural biology and crystallization communications 20070701

Crystallographic snapshots of oxalyl-CoA decarboxylase give insights into catalysis by nonoxidative ThDP-dependent decarboxylases.

Structure (London, England : 1993) 20070701

An activity, stability and selectivity comparison of propioin synthesis by thiamine diphosphate-dependent enzymes in a solid/gas bioreactor.

Chembiochem : a European journal of chemical biology 20070618

[Thiamine and its derivates in cattle blood measured by HPLC in healthy animals, in patients suffering from CCN and in their cohorts].

DTW. Deutsche tierarztliche Wochenschrift 20070601

Feasibility of gas/solid carboligation: conversion of benzaldehyde to benzoin using thiamine diphosphate-dependent enzymes.

Journal of biotechnology 20070510

Crystal structure of the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex.

Journal of molecular biology 20070504

Cloning and characterization of a gene encoding phosphoketolase in a Lactobacillus paraplantarum isolated from Kimchi.

Journal of microbiology and biotechnology 20070501

Mechanism-based inactivation of benzoylformate decarboxylase, a thiamin diphosphate-dependent enzyme.

Journal of the American Chemical Society 20070411

Ligand binding and gene control characteristics of tandem riboswitches in Bacillus anthracis.

RNA (New York, N.Y.) 20070401

Adenosine triphosphate and thiamine cross paths.

Nature chemical biology 20070401

Structure, mechanism and catalytic duality of thiamine-dependent enzymes.

Cellular and molecular life sciences : CMLS 20070401

Biosynthesis of thiamin thiazole in eukaryotes: conversion of NAD to an advanced intermediate.

Journal of the American Chemical Society 20070314

Inhibition of pyruvate decarboxylase from Z. mobilis by novel analogues of thiamine pyrophosphate: investigating pyrophosphate mimics.

Chemical communications (Cambridge, England) 20070307

The THI-box riboswitch, or how RNA binds thiamin pyrophosphate.

Structure (London, England : 1993) 20070301

Distinct modes of recognition of the lipoyl domain as substrate by the E1 and E3 components of the pyruvate dehydrogenase multienzyme complex.

Journal of molecular biology 20070209

Which stage of the process of apotransketolase interaction with thiamine diphosphate is affected by the regulatory activity of the donor substrate?

IUBMB life 20070201

RNA ligands that distinguish metabolite-induced conformations in the TPP riboswitch.

Angewandte Chemie (International ed. in English) 20070101

Influence of donor substrate on kinetic parameters of thiamine diphosphate binding to transketolase.

Biochemistry. Biokhimiia 20070101

Enzyme-catalyzed side reactions with molecular oxygen may contribute to cell signaling and neurodegenerative diseases.

Neurochemical research 20070101

Presence of thiamine pyrophosphate in mammalian peroxisomes.

BMC biochemistry 20070101

Restoration of thiamine status with white or whole wheat bread in a thiamine-depleted rat model.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070101

[Characteristic metabolic disturbances in the rat tissues caused by long-term use of alcohol].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101

Factors mediating activity, selectivity, and substrate specificity for the thiamin diphosphate-dependent enzymes benzaldehyde lyase and benzoylformate decarboxylase.

Chembiochem : a European journal of chemical biology 20061201

Synthesis with good enantiomeric excess of both enantiomers of alpha-ketols and acetolactates by two thiamin diphosphate-dependent decarboxylases.

Bioorganic chemistry 20061201

Theoretical model of interactions between ligand-binding sites in a dimeric protein and its application for the analysis of thiamine diphosphate binding to yeast transketolase.

Biophysical chemistry 20061120

Function of a conserved loop of the beta-domain, not involved in thiamin diphosphate binding, in catalysis and substrate activation in yeast pyruvate decarboxylase.

Biochemistry 20061114

Active-site changes in the pyruvate dehydrogenase multienzyme complex E1 apoenzyme component from Escherichia coli observed at 2.32 A resolution.

Acta crystallographica. Section D, Biological crystallography 20061101

Structure of the thiazole biosynthetic enzyme THI1 from Arabidopsis thaliana.

The Journal of biological chemistry 20061013

Thiamin nutrition and catalysis-induced instability of thiamin diphosphate.

The British journal of nutrition 20061001

A Korean female patient with thiamine-responsive pyruvate dehydrogenase complex deficiency due to a novel point mutation (Y161C)in the PDHA1 gene.

Journal of Korean medical science 20061001

Phosphate-group recognition by the aptamer domain of the thiamine pyrophosphate sensing riboswitch.

Chembiochem : a European journal of chemical biology 20060901

Crystal structures of the thi-box riboswitch bound to thiamine pyrophosphate analogs reveal adaptive RNA-small molecule recognition.

Structure (London, England : 1993) 20060901

Thiamine models and perspectives on the mechanism of action of thiamine-dependent enzymes.

Chemical Society reviews 20060801

Domain relationships in thiamine diphosphate-dependent enzymes.

Accounts of chemical research 20060801

Flipping off the riboswitch: RNA structures that control gene expression.

ACS chemical biology 20060721

Thiamine pyrophosphate: an essential cofactor for the alpha-oxidation in mammals--implications for thiamine deficiencies?

Cellular and molecular life sciences : CMLS 20060701

Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch.

Nature 20060629

Structural biology: RNA switches function.

Nature 20060629

Electronic and nuclear magnetic resonance spectroscopic features of the 1',4'-iminopyrimidine tautomeric form of thiamin diphosphate, a novel intermediate on enzymes requiring this coenzyme.

Biochemistry 20060620

EPR spectroscopic and computational characterization of the hydroxyethylidene-thiamine pyrophosphate radical intermediate of pyruvate:ferredoxin oxidoreductase.

Biochemistry 20060613

Thiamin biosynthesis in eukaryotes: characterization of the enzyme-bound product of thiazole synthase from Saccharomyces cerevisiae and its implications in thiazole biosynthesis.

Journal of the American Chemical Society 20060607

The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography.

Nature chemical biology 20060601

Snapshots of three intermediates at the active site of pyruvate oxidase.

Nature chemical biology 20060601

Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand.

Science (New York, N.Y.) 20060526

The electrochemical investigation of the catalytic power of pyruvate decarboxylase and its coenzyme.

Bioelectrochemistry (Amsterdam, Netherlands) 20060501

Flexibility of thiamine diphosphate revealed by kinetic crystallographic studies of the reaction of pyruvate-ferredoxin oxidoreductase with pyruvate.

Structure (London, England : 1993) 20060201

A versatile conformational switch regulates reactivity in human branched-chain alpha-ketoacid dehydrogenase.

Structure (London, England : 1993) 20060201

Structural studies of the purine and SAM binding riboswitches.

Cold Spring Harbor symposia on quantitative biology 20060101

[Liquid chromatographic determination of free thiamine and its esters in whole blood].

Dakar medical 20060101

Structural basis for activation of the thiamin diphosphate-dependent enzyme oxalyl-CoA decarboxylase by adenosine diphosphate.

The Journal of biological chemistry 20051216

Inclusion of thiamine diphosphate and S-adenosylmethionine at their chemically active sites.

The Journal of organic chemistry 20051209

The relationship between plasma and red cell B-vitamin concentrations in critically-ill patients.

Clinical nutrition (Edinburgh, Scotland) 20051201

Structure and mechanism of the ThDP-dependent benzaldehyde lyase from Pseudomonas fluorescens.

The FEBS journal 20051201

Thiamine pyrophosphate riboswitches are targets for the antimicrobial compound pyrithiamine.

Chemistry & biology 20051201

Cofactor activation and substrate binding in pyruvate decarboxylase. Insights into the reaction mechanism from molecular dynamics simulations.

Biochemistry 20051115

Radical phosphate transfer mechanism for the thiamin diphosphate- and FAD-dependent pyruvate oxidase from Lactobacillus plantarum. Kinetic coupling of intercofactor electron transfer with phosphate transfer to acetyl-thiamin diphosphate via a transient FAD semiquinone/hydroxyethyl-ThDP radical pair.

Biochemistry 20051011

Genetic regulation mediated by thiamin pyrophosphate-binding motif in Saccharomyces cerevisiae.

Molecular microbiology 20051001

Modification of thiamine pyrophosphate dependent enzyme activity by oxythiamine in Saccharomyces cerevisiae cells.

Canadian journal of microbiology 20051001

Multiple modes of active center communication in thiamin diphosphate-dependent enzymes.

Accounts of chemical research 20050901

Topological analysis of the electron density in model azolium systems for thiamin structure-function: sulfur is the electron sink and positively polarized carbanions act as nucleophiles.

The journal of physical chemistry. A 20050825

The analysis of thiamin and its derivatives in whole blood samples under high pH conditions of the mobile phase.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805

Studies on thiamine diphosphate-dependent enzymes.

Biochemical Society transactions 20050801

The potential role of thiamine (vitamin B1) in diabetic complications.

Current diabetes reviews 20050801

Exchanging the substrate specificities of pyruvate decarboxylase from Zymomonas mobilis and benzoylformate decarboxylase from Pseudomonas putida.

Protein engineering, design & selection : PEDS 20050701

Binding of the coenzyme and formation of the transketolase active center.

IUBMB life 20050701

Effect of transketolase substrates on holoenzyme reconstitution and stability.

Biochemistry. Biokhimiia 20050701

Kinetic control of thiamin diphosphate activation in enzymes studied by proton-nitrogen correlated NMR spectroscopy.

Biochemistry 20050621

Glutamate 636 of the Escherichia coli pyruvate dehydrogenase-E1 participates in active center communication and behaves as an engineered acetolactate synthase with unusual stereoselectivity.

The Journal of biological chemistry 20050603

Experimental observation of thiamin diphosphate-bound intermediates on enzymes and mechanistic information derived from these observations.

Bioorganic chemistry 20050601

Roles of Mg2+ in TPP-dependent riboswitch.

FEBS letters 20050509

How an enzyme answers multiple-choice questions.

Trends in biochemical sciences 20050501

Intermediates and transition states in thiamin diphosphate-dependent decarboxylases. A kinetic and NMR study on wild-type indolepyruvate decarboxylase and variants using indolepyruvate, benzoylformate, and pyruvate as substrates.

Biochemistry 20050426

Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids.

The Journal of biological chemistry 20050318

Biosynthesis of hydroxymethylpyrimidine pyrophosphate in Saccharomyces cerevisiae.

Current genetics 20050301

Determination of thiamine and its phosphate esters in rat tissues analyzed as thiochromes on a RP-amide C16 column.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

Evidence for dramatic acceleration of a C-H bond ionization rate in thiamin diphosphate enzymes by the protein environment.

Biochemistry 20050222

Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase.

Biochemistry 20050222

Outbreak of life-threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula.

Pediatrics 20050201

Suicide inhibition of acetohydroxyacid synthase by hydroxypyruvate.

Journal of enzyme inhibition and medicinal chemistry 20050201

Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes.

Malaria journal 20050101

Adult hypophosphatasia and a low level of red blood cell thiamine pyrophosphate.

Annals of nutrition & metabolism 20050101

Interaction of thiamin diphosphate with phosphorylated and dephosphorylated mammalian pyruvate dehydrogenase complex.

Biological chemistry 20050101

[Functional activity of blood and liver cells under formaldehyde intoxication via inhalation].

Biomeditsinskaia khimiia 20050101

Erythrocyte thiamine (Th) esters: a major factor of the alcohol withdrawal syndrome or a candidate marker for alcoholism itself?

Alcohol and alcoholism (Oxford, Oxfordshire) 20050101

Assay values for thiamine or thiamine phosphate esters in whole blood do not depend on the anticoagulant used.

Journal of clinical laboratory analysis 20050101

C2-alpha-lactylthiamin diphosphate is an intermediate on the pathway of thiamin diphosphate-dependent pyruvate decarboxylation. Evidence on enzymes and models.

The Journal of biological chemistry 20041224

[Erythrocyte transketolase].

Nihon rinsho. Japanese journal of clinical medicine 20041201

Suicidal dephosphorylation of thiamine pyrophosphate coupled with pyruvate dehydrogenase complex.

The Italian journal of biochemistry 20041201

Effects of deletions at the C-terminus of tobacco acetohydroxyacid synthase on the enzyme activity and cofactor binding.

The Biochemical journal 20041115

Donor substrate regulation of transketolase.

European journal of biochemistry 20041101

Biochemistry. How active sites communicate in thiamine enzymes.

Science (New York, N.Y.) 20041029

A molecular switch and proton wire synchronize the active sites in thiamine enzymes.

Science (New York, N.Y.) 20041029

The relationship between plasma and red cell concentrations of vitamins thiamine diphosphate, flavin adenine dinucleotide and pyridoxal 5-phosphate following elective knee arthroplasty.

Clinical nutrition (Edinburgh, Scotland) 20041001

Thiamine pyrophosphate biosynthesis and transport in the nematode Caenorhabditis elegans.

Genetics 20041001

Optical characteristics of thiamine in model systems and in holoenzyme.

Biochemistry. Biokhimiia 20040901

The molecular origin of the thiamine diphosphate-induced spectral bands of ThDP-dependent enzymes.

Proteins 20040801

A new perspective on thiamine catalysis.

Current opinion in biotechnology 20040801

Electron transfer in acetohydroxy acid synthase as a side reaction of catalysis. Implications for the reactivity and partitioning of the carbanion/enamine form of (alpha-hydroxyethyl)thiamin diphosphate in a 'nonredox' flavoenzyme.

Biochemistry 20040713

Obese individuals as thiamin storers.

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040701

Inhibition of thiamin diphosphate dependent enzymes by 3-deazathiamin diphosphate.

Organic & biomolecular chemistry 20040621

Kinetic study of the H103A mutant yeast transketolase.

FEBS letters 20040604

The role of cysteine 160 in thiamine diphosphate binding of the Calvin-Benson-Bassham cycle transketolase of Rhodobacter sphaeroides.

Archives of biochemistry and biophysics 20040601

Tetrahedral intermediates in thiamin diphosphate-dependent decarboxylations exist as a 1',4'-imino tautomeric form of the coenzyme, unlike the michaelis complex or the free coenzyme.

Biochemistry 20040601

Structural and biochemical basis for novel mutations in homozygous Israeli maple syrup urine disease patients: a proposed mechanism for the thiamin-responsive phenotype.

The Journal of biological chemistry 20040423

The reaction of dimethyltin(IV) dichloride with thiamine diphosphate (H2TDP): synthesis and structure of [SnMe2(HTDP)(H2O)]Cl.H2O, and possibility of a hitherto unsuspected role of the metal cofactor in the mechanism of vitamin-B1-dependent enzymes.

Inorganic chemistry 20040322

Structural determinants of enzyme binding affinity: the E1 component of pyruvate dehydrogenase from Escherichia coli in complex with the inhibitor thiamin thiazolone diphosphate.

Biochemistry 20040309

Thiamine binding and metabolism in germinating seeds of selected cereals and legumes.

Plant physiology and biochemistry : PPB 20040301

The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate.

The Journal of biological chemistry 20040116

The active site and mechanism of action of recombinant acetohydroxy acid synthase from tobacco.

FEBS letters 20031204

Effect of thiamine on 3H-MPP+ uptake by Caco-2 cells.

Pharmacological research 20031201

Three thiamine analogues differently alter thiamine transport and metabolism in nervous tissue: an in vivo kinetic study using rats.

Metabolic brain disease 20031201

Steady-state kinetics and molecular evolution of Escherichia coli MenD [(1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase], an anomalous thiamin diphosphate-dependent decarboxylase-carboligase.

Biochemistry 20031125

An efficient enzymatic synthesis of thiamin pyrophosphate.

Bioorganic & medicinal chemistry letters 20031117

Dual catalytic apparatus of the thiamin diphosphate coenzyme: acid-base via the 1',4'-iminopyrimidine tautomer along with its electrophilic role.

Journal of the American Chemical Society 20031022

Genetic control by metabolite-binding riboswitches.

Chembiochem : a European journal of chemical biology 20031006

Structure and properties of an engineered transketolase from maize.

Plant physiology 20030801

NMR analysis of covalent intermediates in thiamin diphosphate enzymes.

Biochemistry 20030708

Structural basis for flip-flop action of thiamin pyrophosphate-dependent enzymes revealed by human pyruvate dehydrogenase.

The Journal of biological chemistry 20030606

Metabolite-binding RNA domains are present in the genes of eukaryotes.

RNA (New York, N.Y.) 20030601

Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid.

European journal of biochemistry 20030501

Studies on structure-function relationships of indolepyruvate decarboxylase from Enterobacter cloacae, a key enzyme of the indole acetic acid pathway.

European journal of biochemistry 20030501

Current mechanistic understanding of thiamin diphosphate-dependent enzymatic reactions.

Natural product reports 20030401

Pyruvate:NADP+ oxidoreductase is stabilized by its cofactor, thiamin pyrophosphate, in mitochondria of Euglena gracilis.

Archives of biochemistry and biophysics 20030315

Structural and kinetic analysis of catalysis by a thiamin diphosphate-dependent enzyme, benzoylformate decarboxylase.

Biochemistry 20030225

The coenzyme thiamine pyrophosphate inhibits the self-splicing of the group I intron.

The international journal of biochemistry & cell biology 20030201

Effect of intravenous infusions of thiamine on the disposition kinetics of thiamine and its pyrophosphate.

Journal of clinical pharmacy and therapeutics 20030201

Induced absorption band of holotransketolase and its interpretation.

Biochemistry. Biokhimiia 20030201

Biochemical characterization of two mutants of human pyruvate dehydrogenase, F205L and T231A of the E1alpha subunit.

Journal of inherited metabolic disease 20030101

Thiamine pyrophosphate: an essential cofactor in the mammalian metabolism of 3-methyl-branched fatty acids--implications for thiamine deficiencies?

Advances in experimental medicine and biology 20030101

Thiamin-diphosphate-dependent enzymes: new aspects of asymmetric C-C bond formation.

Chemistry (Weinheim an der Bergstrasse, Germany) 20021202

A (ribo) switch in the paradigms of genetic regulation.

Nature structural biology 20021201

Identification and reconstitution of the yeast mitochondrial transporter for thiamine pyrophosphate.

The EMBO journal 20021101

Molecular biology: RNA gets a grip on translation.

Nature 20021031

Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression.

Nature 20021031

A novel Y243S mutation in the pyruvate dehydrogenase El alpha gene subunit: correlation with thiamine pyrophosphate interaction.

Journal of inherited metabolic disease 20020801

Cerebrospinal fluid levels of thiamine in patients with Alzheimer's disease.

Journal of neural transmission (Vienna, Austria : 1996) 20020701

Spectroscopic evidence for participation of the 1',4'-imino tautomer of thiamin diphosphate in catalysis by yeast pyruvate decarboxylase.

Bioorganic chemistry 20020601

The origin of the absorption band induced through the interaction between apotransketolase and thiamin diphosphate.

Biochemical and biophysical research communications 20020531

Structure of the pyruvate dehydrogenase multienzyme complex E1 component from Escherichia coli at 1.85 A resolution.

Biochemistry 20020423

[Drug therapy for mitochondrial diseases].

Nihon rinsho. Japanese journal of clinical medicine 20020401

Growth-phase dependent expression of the mevalonate pathway in a terpenoid antibiotic-producing Streptomyces strain.

Bioscience, biotechnology, and biochemistry 20020401

Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors.

Journal of molecular biology 20020322

Practical tethering of vitamin B1 on a silica surface via its phosphate group and evaluation of its activity.

Chemical communications (Cambridge, England) 20020307

Evaluation of oxidative stress indices during treatment in pregnant women with intrauterine growth retardation.

Medical science monitor : international medical journal of experimental and clinical research 20020301

Thiamine deficiency in hepatitis C virus and alcohol-related liver diseases.

Digestive diseases and sciences 20020301

Simultaneous detection of thiamine and its phosphate esters from microalgae by HPLC.

Biochemical and biophysical research communications 20020222

Characterization of a missense mutation at histidine-44 in a pyruvate dehydrogenase-deficient patient.

Biochimica et biophysica acta 20020102

Reduced serum concentrations of riboflavine and ascorbic acid, and blood thiamine pyrophosphate and pyridoxal-5-phosphate in geriatric patients with and without pressure sores.

The journal of nutrition, health & aging 20020101

Mitochondria from cultured cells derived from normal and thiamine-responsive megaloblastic anemia individuals efficiently import thiamine diphosphate.

BMC biochemistry 20020101

[Relative reactivity of thiamine monophosphate and thiamine diphosphate upon interaction with alkaline phosphatase].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101

Regulation of mammalian pyruvate dehydrogenase complex by phosphorylation: complexity of multiple phosphorylation sites and kinases.

Experimental & molecular medicine 20011231

Enzymology. Coenzymes and radicals.

Science (New York, N.Y.) 20011221

Crystal structure of the free radical intermediate of pyruvate:ferredoxin oxidoreductase.

Science (New York, N.Y.) 20011221

Cooperation of divalent ions and thiamin diphosphate in regulation of the function of pig heart pyruvate dehydrogenase complex.

Journal of nutritional science and vitaminology 20011201

Binding and activation of thiamin diphosphate in acetohydroxyacid synthase.

Biochemistry 20011002

Functional flexibility of the transketolase molecule.

Biochemistry. Biokhimiia 20011001

The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite.

Bioorganic & medicinal chemistry letters 20010903

Thiamin auxotrophy in yeast through altered cofactor dependence of the enzyme acetohydroxyacid synthase.

Microbiology (Reading, England) 20010901

Complexation of Cu(2+) by HETPP and the pentapeptide Asp-Asp-Asn-Lys-Ile: a structural model of the active site of thiamin-dependent enzymes in solution.

Inorganic chemistry 20010827

Regulation of pyruvate dehydrogenase activity through phosphorylation at multiple sites.

The Biochemical journal 20010815

Cleaving of ketosubstrates by transketolase and the nature of the products formed.

Biochemistry. Biokhimiia 20010801

Catalytic acid-base groups in yeast pyruvate decarboxylase. 1. Site-directed mutagenesis and steady-state kinetic studies on the enzyme with the D28A, H114F, H115F, and E477Q substitutions.

Biochemistry 20010626

Examination of donor substrate conversion in yeast transketolase.

The Journal of biological chemistry 20010511

The use of thiamine and thiamine antagonists to investigate the etiology of early mortality syndrome in lake trout (Salvelinus namaycush).

Aquatic toxicology (Amsterdam, Netherlands) 20010501

Molecular mechanisms of thiamine utilization.

Current molecular medicine 20010501

Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates.

Archives of biochemistry and biophysics 20010215

Inhibitors of advanced glycation end product-associated protein cross-linking.

Biochimica et biophysica acta 20010214

Consequences of a modified putative substrate-activation site on catalysis by yeast pyruvate decarboxylase.

Biochemistry 20010213

Impact of the reduced folate carrier on the accumulation of active thiamin metabolites in murine leukemia cells.

The Journal of biological chemistry 20010112

Transketolase abnormality in tolazamide-induced Wernicke's encephalopathy.

Neurology 19861101

Protection against misonidazole-induced neuropathy in rats: a biochemical assessment.

Toxicology letters 19830601

The pyruvate-dehydrogenase complex from Azotobacter vinelandii. 2. Regulation of the activity.

European journal of biochemistry 19751115