(-)-PERILLYL ALCOHOL
| Title | Journal |
|---|---|
| The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells. | Biochimie 20121201 |
| Analysis of EGF+61A>G polymorphism and EGF serum levels in Brazilian glioma patients treated with perillyl alcohol-based therapy. | Journal of cancer research and clinical oncology 20120801 |
| Calcium blockers decrease the bortezomib resistance in mantle cell lymphoma via manipulation of tissue transglutaminase activities. | Blood 20120315 |
| Influence of the active compounds of Perilla frutescens leaves on lipid membranes. | Journal of natural products 20120224 |
| Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles. | International journal of nanomedicine 20120101 |
| Microbial hydroxylation of S-(-)-perillyl alcohol by Fusarium heterosporium. | Natural product communications 20111201 |
| Nonmelanoma skin cancer chemoprevention. | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20111101 |
| Cell physiology rather than enzyme kinetics can determine the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization. | Journal of industrial microbiology & biotechnology 20110901 |
| Evaluation of the antioxidant and antiproliferative potential of bioflavors. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701 |
| An efficient route to selective bio-oxidation catalysts: an iterative approach comprising modeling, diversification, and screening, based on CYP102A1. | Chembiochem : a European journal of chemical biology 20110614 |
| Efficacy of monoterpene perillyl alcohol upon survival rate of patients with recurrent glioblastoma. | Journal of cancer research and clinical oncology 20110201 |
| Perillyl alcohol protects against ethanol induced acute liver injury in Wistar rats by inhibiting oxidative stress, NFκ-B activation and proinflammatory cytokine production. | Toxicology 20110111 |
| Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol. | Journal of proteome research 20110107 |
| The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor. | Molecular and cellular biochemistry 20101201 |
| Dynamic proteomic overview of glioblastoma cells (A172) exposed to perillyl alcohol. | Journal of proteomics 20100310 |
| A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer. | Cancer prevention research (Philadelphia, Pa.) 20100201 |
| The promise of natural products for blocking early events in skin carcinogenesis. | Cancer prevention research (Philadelphia, Pa.) 20100201 |
| Perillyl alcohol and methyl jasmonate sensitize cancer cells to cisplatin. | Anti-cancer drugs 20100101 |
| Correlation of tumor topography and peritumoral edema of recurrent malignant gliomas with therapeutic response to intranasal administration of perillyl alcohol. | Investigational new drugs 20091201 |
| Tricistronic overexpression of cytochrome P450cam, putidaredoxin, and putidaredoxin reductase provides a useful cell-based catalytic system. | Biotechnology letters 20090901 |
| Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis. | Chemico-biological interactions 20090515 |
| Components of lemon essential oil attenuate dementia induced by scopolamine. | Nutritional neuroscience 20090401 |
| Protective effects of mastic oil from Pistacia lentiscus variation chia against experimental growth of lewis lung carcinoma. | Nutrition and cancer 20090101 |
| High-performance liquid chromatographic and pharmacokinetic analyses of an intravenous submicron emulsion of perillyl alcohol in rats. | Journal of pharmaceutical and biomedical analysis 20081201 |
| Fragrance material review on p-mentha-1,8-dien-7-ol. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101 |
| Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol. | Cancer research 20080915 |
| Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas. | Surgical neurology 20080901 |
| Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol. | Archivum immunologiae et therapiae experimentalis 20080801 |
| Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells. | Bioorganic & medicinal chemistry letters 20080715 |
| Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis. | Molecular cancer therapeutics 20080701 |
| A pilot study of perillyl alcohol in pancreatic cancer. | The Journal of surgical research 20080615 |
| Phase II trial of daily oral perillyl alcohol (NSC 641066) in treatment-refractory metastatic breast cancer. | Cancer chemotherapy and pharmacology 20080601 |
| Anti-inflammatory senescence actives 5203-L molecule to promote healthy aging and prolongation of lifespan. | Rejuvenation research 20080401 |
| Phase 1 study of topical perillyl alcohol cream for chemoprevention of skin cancer. | Nutrition and cancer 20080101 |
| Anti-thrombin as a prognostic biomarker candidate for patients with recurrent glioblastoma multiform under treatment with perillyl alcohol. | Journal of experimental therapeutics & oncology 20080101 |
| Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells. | Cancer letters 20071118 |
| Modifications of the chemical structure of terpenes in antiplasmodial and antifungal drug research. | Bioorganic & medicinal chemistry letters 20071115 |
| Perillyl alcohol and genistein differentially regulate PKB/Akt and 4E-BP1 phosphorylation as well as eIF4E/eIF4G interactions in human tumor cells. | Archives of biochemistry and biophysics 20070901 |
| Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells. | The Journal of pharmacology and experimental therapeutics 20070301 |
| Anaplastic oligodendroglioma responding favorably to intranasal delivery of perillyl alcohol: a case report and literature review. | Surgical neurology 20061201 |
| Polycyclic aromatic hydrocarbon-induced CYP1B1 activity is suppressed by perillyl alcohol in MCF-7 cells. | Toxicology and applied pharmacology 20060601 |
| Perillyl alcohol inhibits the expression and function of the androgen receptor in human prostate cancer cells. | Cancer letters 20060518 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Recent advances in the molecular genetics of malignant gliomas disclose targets for antitumor agent perillyl alcohol. | Surgical neurology 20060101 |
| Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells. | Oncology 20060101 |
| Mastic oil from Pistacia lentiscus var. chia inhibits growth and survival of human K562 leukemia cells and attenuates angiogenesis. | Nutrition and cancer 20060101 |
| In vitro induction of apoptosis in U937 cells by perillyl alcohol with sensitization by pentoxifylline: increased BCL-2 and BAX protein expression. | Chemotherapy 20060101 |
| Effects of perillyl alcohol and heat shock treatment in gene expression of human lung adenocarcinoma cell line A549. | Journal of experimental therapeutics & oncology 20060101 |
| Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kappaB pathway. | Cancer research 20050915 |
| Effect of D-limonene on immune response in BALB/c mice with lymphoma. | International immunopharmacology 20050501 |
| Perillyl alcohol induces apoptosis in human glioblastoma multiforme cells. | Oncology reports 20050501 |
| CaaX-prenyltransferases are essential for expression of genes involvedin the early stages of monoterpenoid biosynthetic pathway in Catharanthus roseus cells. | Plant molecular biology 20050401 |
| An HPLC method for quantitation of perillyl alcohol in a topical pharmaceutical cream formulation. | Journal of pharmaceutical and biomedical analysis 20050309 |
| Protein and m-RNA expression of farnesyl-transferases, RhoA and RhoB in rat liver hepatocytes: action of perillyl alcohol and vitamin A in vivo. | Journal of biomedical science 20050101 |
| A pilot surrogate end point biomarker trial of perillyl alcohol in breast neoplasia. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041115 |
| Perillyl alcohol is an angiogenesis inhibitor. | The Journal of pharmacology and experimental therapeutics 20041101 |
| A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days. | Cancer chemotherapy and pharmacology 20041001 |
| Perillyl alcohol inhibits human breast cancer cell growth in vitro and in vivo. | Breast cancer research and treatment 20040401 |
| Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: potential mechanisms for its chemotherapeutic effects. | Toxicology and applied pharmacology 20040301 |
| Development of a perillyl alcohol topical cream formulation. | International journal of pharmaceutics 20040128 |
| Effects of POH in combination with STI571 on the proliferation and apoptosis of K562 cells. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20040101 |
| Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro. | Anticancer research 20040101 |
| Effect of antiproliferative agents on vascular function in normal and in vitro balloon-injured porcine coronary arteries. | European journal of pharmacology 20031114 |
| Phase I trial of perillyl alcohol administered four times daily continuously. | Cancer chemotherapy and pharmacology 20031101 |
| Cytotoxicity of perillyl alcohol against cancer cells is potentiated by hyperthermia. | International journal of radiation oncology, biology, physics 20031101 |
| Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro. | Life sciences 20031017 |
| Studies with cytotoxic agents suggest that apoptosis is not a major determinant of clonogenic death in neuroblastoma cells. | European journal of cancer (Oxford, England : 1990) 20031001 |
| Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Raf-independent fashion. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031001 |
| Perillyl alcohol as a radio-/chemosensitizer in malignant glioma. | The Journal of biological chemistry 20030919 |
| Perillyl alcohol mediated radiosensitization via augmentation of the Fas pathway in prostate cancer cells. | The Prostate 20030915 |
| Phase II trial of perillyl alcohol (NSC 641066) administered daily in patients with metastatic androgen independent prostate cancer. | Investigational new drugs 20030801 |
| Monoterpene regulation of Ras and Ras-related protein expression. | Journal of lipid research 20030601 |
| A phase I trial of perillyl alcohol in patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20030601 |
| Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis. | Cancer research 20030515 |
| Effects of perillyl alcohol in glial C6 cell line in vitro and anti-metastatic activity in chorioallantoic membrane model. | International journal of molecular medicine 20021201 |
| Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression. | Cancer letters 20020726 |
| Effects of perillyl alcohol on melanoma in the TPras mouse model. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020601 |
| A phase II trial of daily perillyl alcohol in patients with advanced ovarian cancer: Eastern Cooperative Oncology Group Study E2E96. | Gynecologic oncology 20020601 |
| Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20020501 |
| Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest. | Leukemia 20020201 |
| Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol. | Carcinogenesis 20020101 |
| Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes. | Chemical research in toxicology 20020101 |
| Phase I study of perillyl alcohol in patients with refractory malignancies. | Cancer biology & therapy 20020101 |
| Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention. | Anticancer research 20020101 |
| Phase II trial of perillyl alcohol in patients with metastatic colorectal cancer. | International journal of gastrointestinal cancer 20020101 |