4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]Benzenebutanoic acid
| Title | Journal |
|---|---|
| Prostaglandin receptor EP4 in abdominal aortic aneurysms. | The American journal of pathology 20120701 |
| Oral administration of prostaglandin E(2)-specific receptor 4 antagonist inhibits lipopolysaccharide-induced osteoclastogenesis in rat periodontal tissue. | Journal of periodontology 20120401 |
| Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor. | Journal of neurochemistry 20120301 |
| Prostaglandin E2 enhances interleukin-8 production via EP4 receptor in human pulmonary microvascular endothelial cells. | American journal of physiology. Lung cellular and molecular physiology 20120115 |
| PGE(2) reverses G(s)-mediated inhibition of platelet aggregation by interaction with EP3 receptors, but adds to non-G(s)-mediated inhibition of platelet aggregation by interaction with EP4 receptors. | Platelets 20120101 |
| Inhibition of EP4 signaling attenuates aortic aneurysm formation. | PloS one 20120101 |
| EP4 receptor as a new target for bronchodilator therapy. | Thorax 20111201 |
| The role of PGE(2) in human atherosclerotic plaque on platelet EP(3) and EP(4) receptor activation and platelet function in whole blood. | Journal of thrombosis and thrombolysis 20110801 |
| Prostaglandin EP4 receptor enhances BCR-induced apoptosis of immature B cells. | Prostaglandins & other lipid mediators 20110801 |
| Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptors. | European journal of immunology 20110801 |
| PGE1 and PGE2 modify platelet function through different prostanoid receptors. | Prostaglandins & other lipid mediators 20110201 |
| The prostaglandin E2 receptor EP4 is expressed by human platelets and potently inhibits platelet aggregation and thrombus formation. | Arteriosclerosis, thrombosis, and vascular biology 20101201 |
| Endogenous prostaglandin E2 accelerates healing of indomethacin-induced small intestinal lesions through upregulation of vascular endothelial growth factor expression by activation of EP4 receptors. | Journal of gastroenterology and hepatology 20100501 |
| Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model. | Cancer research 20100215 |
| The role of prostanoid receptors in mediating the effects of PGE(2) on human platelet function. | Platelets 20100101 |
| Orally administered novokinin, an angiotensin AT2 receptor agonist, suppresses food intake via prostaglandin E2-dependent mechanism in mice. | Peptides 20090601 |
| PGE2-receptor subtype EP4-dependent adherence of mastocytoma P-815 cells to matrix components in subcutaneous tissues overlaying inside surface of air pouch cavity in CDF1 mouse. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080801 |
| Prostaglandin E2 induces hypertrophic changes and suppresses alpha-skeletal actin gene expression in rat cardiomyocytes. | Journal of cardiovascular pharmacology 20071101 |
| Involvement of prostaglandin E receptor EP3 subtype in duodenal bicarbonate secretion in rats. | Life sciences 20070606 |
| Prostaglandin E receptor EP4 antagonist suppresses osteolysis due to bone metastasis of mouse malignant melanoma cells. | FEBS letters 20070206 |
| Prostaglandin E2 is required for ultraviolet B-induced skin inflammation via EP2 and EP4 receptors. | Laboratory investigation; a journal of technical methods and pathology 20070101 |
| Prostaglandin E2 receptor EP4-selective antagonist inhibits lipopolysaccharide-induced cervical ripening in rabbits. | Acta obstetricia et gynecologica Scandinavica 20070101 |
| Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism. | Cancer research 20061001 |
| Prostaglandin E receptor EP4 antagonism inhibits breast cancer metastasis. | Cancer research 20060315 |
| Targeting prostaglandin E2 receptors as an alternative strategy to block cyclooxygenase-2-dependent extracellular matrix-induced matrix metalloproteinase-9 expression by macrophages. | The Journal of biological chemistry 20060210 |
| In vivo constriction of the fetal and neonatal ductus arteriosus by a prostanoid EP4-receptor antagonist in rats. | Pediatric research 20051101 |
| Dominant role of prostaglandin E2 EP4 receptor in furosemide-induced salt-losing tubulopathy: a model for hyperprostaglandin E syndrome/antenatal Bartter syndrome. | Journal of the American Society of Nephrology : JASN 20050801 |
| Participation of prostaglandin E receptor EP4 subtype in duodenal bicarbonate secretion in rats. | American journal of physiology. Gastrointestinal and liver physiology 20040701 |
| The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut. | The Journal of clinical investigation 20020401 |