Home Aminos S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide

S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide

CAS No.:
401900-40-1
Catalog Number:
AG00C6E9
Molecular Formula:
C19H18F3N3O6
Molecular Weight:
441.3579
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
95%
In Stock USA
United States
$87
- +
10mg
95%
In Stock USA
United States
$116
- +
50mg
95%
In Stock USA
United States
$214
- +
100mg
95%
In Stock USA
United States
$283
- +
Product Description
Catalog Number:
AG00C6E9
Chemical Name:
S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide
CAS Number:
401900-40-1
Molecular Formula:
C19H18F3N3O6
Molecular Weight:
441.3579
MDL Number:
MFCD09027386
IUPAC Name:
(2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
InChI:
InChI=1S/C19H18F3N3O6/c1-11(26)23-12-3-6-14(7-4-12)31-10-18(2,28)17(27)24-13-5-8-16(25(29)30)15(9-13)19(20,21)22/h3-9,28H,10H2,1-2H3,(H,23,26)(H,24,27)/t18-/m0/s1
InChI Key:
YVXVTLGIDOACBJ-SFHVURJKSA-N
SMILES:
CC(=O)Nc1ccc(cc1)OC[C@@](C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+](=O)[O-])(O)C
UNII:
7UT2HAH49H
Properties
Complexity:
663  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
441.115g/mol
Formal Charge:
0
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
441.363g/mol
Monoisotopic Mass:
441.115g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
134A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.2  
Literature
Title Journal
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters 20130801
SARM-S4 and metabolites detection in sports drug testing: a case report. Forensic science international 20111210
Mass spectrometric characterization of urinary metabolites of the selective androgen receptor modulator andarine (S-4) for routine doping control purposes. Rapid communications in mass spectrometry : RCM 20100815
Effects of a novel selective androgen receptor modulator on dexamethasone-induced and hypogonadism-induced muscle atrophy. Endocrinology 20100801
[Bone and Men's Health. Bone selective androgen receptor modulators]. Clinical calcium 20100201
Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit. Journal of medicinal chemistry 20090625
Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators. Bioorganic & medicinal chemistry letters 20081015
Selective Androgen Receptor Modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats. Pharmaceutical research 20070201
In vivo metabolism and final disposition of a novel nonsteroidal androgen in rats and dogs. Drug metabolism and disposition: the biological fate of chemicals 20061001
Selective androgen receptor modulator treatment improves muscle strength and body composition and prevents bone loss in orchidectomized rats. Endocrinology 20051101
A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor. Journal of medicinal chemistry 20040715
Pharmacokinetics of S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro- 3-trifluoromethyl-phenyl)-propionamide in rats, a non-steroidal selective androgen receptor modulator. Xenobiotica; the fate of foreign compounds in biological systems 20040301
Properties