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SODIUM BARBITURATE

CAS No.:
4390-16-3
Catalog Number:
AG00D9QD
Molecular Formula:
Molecular Weight:
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Purity
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Product Description
Catalog Number:
AG00D9QD
Chemical Name:
SODIUM BARBITURATE
CAS Number:
4390-16-3
MDL Number:
MFCD00065377
IUPAC Name:
sodium;2,6-dioxo-5H-pyrimidin-4-olate
InChI:
InChI=1S/C4H4N2O3.Na/c7-2-1-3(8)6-4(9)5-2;/h1H2,(H2,5,6,7,8,9);/q;+1/p-1
InChI Key:
MHQHHBYRYFICDV-UHFFFAOYSA-M
EC Number:
224-507-3
RTECS Number:
CQ7280000
Properties
Complexity:
201  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
150.004g/mol
Formal Charge:
0
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
150.069g/mol
Monoisotopic Mass:
150.004g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
81.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
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Lewis acid-catalyzed intramolecular [3+2] cycloaddition of cyclopropane 1,1-diesters with alkynes for the synthesis of cyclopenta[c]chromene skeletons. Chemistry, an Asian journal 20120601
Synthesis of 5-alkylated barbituric acids and 3-alkylated indoles via microwave-assisted three-component reactions in solvent-free conditions using Hantzsch 1,4-dihydropyridines as reducing agents. Molecular diversity 20120501
Correction for nonspecific binding to various components of ultrafiltration apparatus and impact on estimating in vivo rat clearance for a congeneric series of 5-ethyl, 5-n-alkyl barbituric acids. Drug metabolism and disposition: the biological fate of chemicals 20111201
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Barbiturate ingestion in three adult captive tigers (Panthera tigris) and concomitant fatal botulism of one. Journal of the South African Veterinary Association 20111201
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New one-pot synthesis of spiro[furo[2,3-d]pyrimidine-6,5'-pyrimidine]pentaones and their sulfur analogues. Molecular diversity 20110801
Synthesis and biological activity of novel barbituric and thiobarbituric acid derivatives against non-alcoholic fatty liver disease. European journal of medicinal chemistry 20110601
A novel agonist of PPAR-γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance. European journal of pharmacology 20110601
Development of a dispersive liquid-liquid microextraction method for spectrophotometric determination of barbituric acid in pharmaceutical formulation and biological samples. Analytical biochemistry 20110515
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Self-assembly of supramolecular fullerene ribbons via hydrogen-bonding interactions and their impact on fullerene electronic interactions and charge carrier mobility. Journal of the American Chemical Society 20100915
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A review of our development of dental adhesives--effects of radical polymerization initiators and adhesive monomers on adhesion. Dental materials journal 20100301
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Loss of olfactory function after exposure to barbituric acid. Auris, nasus, larynx 20100201
A new synthetic approach to functionalize pyrimido[4,5-b]quinoline-2,4(1H,3H)-diones via a three-component one-pot reaction. Molecular diversity 20100201
Rapid and efficient synthesis of fused heterocyclic pyrimidines under ultrasonic irradiation. Ultrasonics sonochemistry 20100101
Hydrogen-bond motifs in N-monosubstituted derivatives of barbituric acid: 5-allyl-5-isopropyl-1-methylbarbituric acid (enallylpropymal) and 1,5-di(but-2-enyl)-5-ethylbarbituric acid. Acta crystallographica. Section C, Crystal structure communications 20100101
The laccase-catalyzed domino reaction between catechols and heterocyclic 1,3-dicarbonyls and the unambiguous structure elucidation of the products by NMR spectroscopy and X-ray crystal structure analysis. The Journal of organic chemistry 20091002
The intravenous anesthetics barbiturates inhibit hypoxia-inducible factor 1 activation. European journal of pharmacology 20090901
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Color change capacity of dental resin mixed with silver methacrylate caused by light irradiation and heating. Dental materials journal 20090501
Reversible transformation between rings and coils in a dynamic hydrogen-bonded self-assembly. Journal of the American Chemical Society 20090422
Voltammetric sensor for barbituric acid based on a sol-gel derivated molecularly imprinted polymer brush grafted to graphite electrode. International journal of pharmaceutics 20090417
Mechanochemical solvent-free and catalyst-free one-pot synthesis of pyrano[2,3-d]pyrimidine-2,4(1H,3H)-diones with quantitative yields. Molecules (Basel, Switzerland) 20090119
Near-infrared fluorescent pH-sensitive probes via unexpected barbituric acid mediated synthesis. Organic letters 20090101
Efficient synthesis of spiro[chromeno[2,3-d]pyrimidine-5,3'-indoline]-tetraones by a one-pot and three-component reaction. Journal of combinatorial chemistry 20090101
Novel one-pot, three-component synthesis of spiro[indoline-pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine]trione library. Journal of combinatorial chemistry 20090101
Highly diastereoselective domino synthesis of 6-spirosubstituted pyrido[2,3-d]pyrimidine derivatives in water. Journal of combinatorial chemistry 20090101
A convenient method for the preparation of barbituric and thiobarbituric acid transition metal complexes. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081201
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Critical roles for fast synaptic transmission in mediating estradiol negative and positive feedback in the neural control of ovulation. Endocrinology 20081101
New PPARgamma ligands based on barbituric acid: virtual screening, synthesis and receptor binding studies. Bioorganic & medicinal chemistry letters 20080915
Probing molecular recognition in the solid-state by use of an enolizable chromophoric barbituric acid. The Journal of organic chemistry 20080704
Proline derived spirobarbiturates as highly effective beta-turn mimetics incorporating polar and functionalizable constraint elements. The Journal of organic chemistry 20080502
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Selective cell adhesion inhibitors: Barbituric acid based alpha4beta7--MAdCAM inhibitors. Bioorganic & medicinal chemistry letters 20080401
Synthesis of barbiturate-based methionine aminopeptidase-1 inhibitors. Bioorganic & medicinal chemistry letters 20080401
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Bonding of autopolymerizing acrylic resins to magnetic stainless steel alloys using metal conditioner. Journal of dentistry 20080201
Novel, multi-purpose, PMMA-type adhesive resin with newly synthesized microcapsule of radical polymerization initiators. Dental materials journal 20080101
An enolisable barbiturate with adjustable hydrogen-bonding structure for UV/Vis detection of nucleic acid bases and related compounds. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
Intensification of ammonium diffusion from rat gastrointestinal tract during acute barbiturate intoxication. Bulletin of experimental biology and medicine 20080101
In vivo oxidative damage in rats is associated with barbiturate response but not other cytochrome P450 inducers. Molecular pharmacology 20071201
[Drug-induced respiratory depression]. Nihon rinsho. Japanese journal of clinical medicine 20071028
Refractory epilepsy accompanying acute encephalitis with multifocal cortical lesions: possible autoimmune etiology. Brain & development 20071001
Crystal structures of MMP-9 complexes with five inhibitors: contribution of the flexible Arg424 side-chain to selectivity. Journal of molecular biology 20070824
Suppression and enhancement of secondary ion formation due to the chemical environment in static-secondary ion mass spectrometry. Journal of the American Society for Mass Spectrometry 20070801
Recognition and dissociation kinetics in the interfacial molecular recognition of barbituric acid by amphiphilic melamine-type monolayers. The journal of physical chemistry. B 20070719
Barbiturate activation and modulation of GABA(A) receptors in neocortex. Neuropharmacology 20070301
Seizures during intracarotid methohexital and amobarbital testing. Epilepsy & behavior : E&B 20070201
Methemoglobinemia after low-dose prilocaine in an adult patient receiving barbiturate comedication. Anesthesia and analgesia 20070201
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GABAmimetic intravenous anaesthetics inhibit spontaneous Ca2+ -oscillations in cultured hippocampal neurons. Acta anaesthesiologica Scandinavica 20060701
Kinetic study on the photostability of riboflavin in the presence of barbituric acid. Redox report : communications in free radical research 20060101
Melamine-barbiturate/cyanurate binary organogels possessing rigid azobenzene-tether moiety. Langmuir : the ACS journal of surfaces and colloids 20051122
Self-assembly and stability of double rosette nanostructures with biological functionalities. Organic & biomolecular chemistry 20051021
Reactions of 3-formylchromone with active methylene and methyl compounds and some subsequent reactions of the resulting condensation products. Molecules (Basel, Switzerland) 20050831
Discriminative stimulus effects of 5.6 mg/kg pregnanolone in DBA/2J and C57BL/6J inbred mice. Alcohol (Fayetteville, N.Y.) 20050801
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Barbiturate withdrawal following Internet purchase of Fioricet. Archives of neurology 20040701
An NMR study of merocyanine-type dyes derived from barbituric acid. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040601
[Usefulness of diffusion-weighted magnetic resonance imaging in diagnosis and therapeutic strategy of deep cerebral venous thrombosis: a case report]. No shinkei geka. Neurological surgery 20040301
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A bifunctional alkylating nitrogen mustard agent that utilizes barbituric acid as carrier drug with the potential for crossing the brain-blood barrier. Receptors & channels 20030101
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Molecular 'chaperones' guide the spontaneous formation of a 15-component hydrogen-bonded assembly. Journal of the American Chemical Society 20020703
Determination of the retention behavior of barbituric acid derivatives in reversed-phase high-performance liquid chromatography by using quantitative structure-retention relationships. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020425
Quantum chemical studies on tautomerism of barbituric acid in gas phase and in solution. Journal of computer-aided molecular design 20020401
Liquid chromatography-mass spectrometry (LC-MS) investigation of the thiobarbituric acid reactive substances (TBARS) reaction. Journal of agricultural and food chemistry 20020313
Barbituric acid initiated rearrangement of 2,2'-pyridil into 5,5'-(2-pyrilidine)bisbarbituric acid. Organic letters 20020307
Influence of physico-chemical parameters of some barbituric acid derivatives on their retention on an amide embedded RP silica column. Journal of pharmaceutical and biomedical analysis 20020301
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Disturbance of cellular iron uptake and utilisation by aluminium. Journal of inorganic biochemistry 20011101
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Comparative tumor-promoting activities of phenobarbital, amobarbital, barbital sodium, and barbituric acid on livers and other organs of male F344/NCr rats following initiation with N-nitrosodiethylamine. Journal of the National Cancer Institute 19850201
Properties