Home Other Building Blocks L-ALPHA-AMINO-GAMMA-[GUANIDINOOXY]-N-BUTYRIC ACID

L-ALPHA-AMINO-GAMMA-[GUANIDINOOXY]-N-BUTYRIC ACID

CAS No.:
543-38-4
Catalog Number:
AG00DBOX
Molecular Formula:
Molecular Weight:
Pack Size
Purity
Availability
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Product Description
Catalog Number:
AG00DBOX
Chemical Name:
L-ALPHA-AMINO-GAMMA-[GUANIDINOOXY]-N-BUTYRIC ACID
CAS Number:
543-38-4
MDL Number:
MFCD00055781
IUPAC Name:
(2S)-2-amino-4-(diaminomethylideneamino)oxybutanoic acid
InChI:
InChI=1S/C5H12N4O3/c6-3(4(10)11)1-2-12-9-5(7)8/h3H,1-2,6H2,(H,10,11)(H4,7,8,9)/t3-/m0/s1
InChI Key:
FSBIGDSBMBYOPN-VKHMYHEASA-N
UNII:
3HZV514J4B
Properties
Complexity:
178  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
176.091g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
176.176g/mol
Monoisotopic Mass:
176.091g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
137A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-4.8  
Literature
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Analysis of underivatized amino acids and their D/L-enantiomers by sheathless capillary electrophoresis/electrospray ionization mass spectrometry. Analytical chemistry 20030315
Comparison of the effects of specific and nonspecific inhibition of nitric oxide synthase on morphine analgesia, tolerance and dependence in mice. Life sciences 20030314
Disseminated cryptococcosis in an AIDS patient caused by a canavanine-resistant strain of Cryptococcus neoformans var. grubii. Journal of medical microbiology 20030301
The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress. The Journal of biological chemistry 20030227
Preservation of neurological functions by nitric oxide synthase inhibitors following hemorrhagic shock. Neuropharmacology 20030201
L-Canavanine as a radiosensitization agent for human pancreatic cancer cells. Molecular and cellular biochemistry 20030201
Screening of substrate analogs as potential enzyme inhibitors for the arginine kinase of Trypanosoma cruzi. The Journal of eukaryotic microbiology 20030101
Ischemia and hepatic reperfusion: is it possible to reduce hepatic alterations? Microsurgery 20030101
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Aggresome-related biogenesis of Lewy bodies. The European journal of neuroscience 20021201
Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae. The Journal of biological chemistry 20021122
Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae. DNA repair 20021103
Multiple associated proteins regulate proteasome structure and function. Molecular cell 20020901
Expression of the Aspergillus fumigatus rheb homologue, rhbA, is induced by nitrogen starvation. Fungal genetics and biology : FG & B 20020801
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Arginine antimetabolite L-canavanine induces apoptotic cell death in human Jurkat T cells via caspase-3 activation regulated by Bcl-2 or Bcl-xL. Biochemical and biophysical research communications 20020712
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Inhibition of inducible nitric oxide synthase attenuates interleukin-1 beta induced vascular hyporeactivity in the rabbit. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20020401
The antiproliferative and immunotoxic effects of L-canavanine and L-canaline. Anti-cancer drugs 20020301
Effect of L-canavanine, an Inhibitor of inducible nitric oxide synthase, on myocardial dysfunction during septic shock. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20020201
AIDS herbal therapy. Trends in plant science 20020201
Cell swelling induced secretion of TRH by posterior pituitary, hypothalamic paraventricular nucleus and pancreatic islets: effect of L-canavanine. Cellular and molecular neurobiology 20020201
MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function. BMC biochemistry 20020101
Effect of null mutations in dnaK and dnaJ genes on conjugational DNA transfer, proteolysis and novobiocin susceptibility of Escherichia coli. Acta microbiologica Polonica 20020101
Sensitivity of mammalian cells expressing mutant ubiquitin to protein-damaging agents. The Journal of biological chemistry 20011207
[The environment and autoimmunity--from external causes to inner conflicts]. Praxis 20011101
Two-hybrid analysis of the Saccharomyces cerevisiae 26S proteasome. Physiological genomics 20011010
Failure to farnesylate Rheb protein contributes to the enrichment of G0/G1 phase cells in the Schizosaccharomyces pombe farnesyltransferase mutant. Molecular microbiology 20010901
Kinetics of CO binding to the haem domain of murine inducible nitric oxide synthase: differential effects of haem domain ligands. The Biochemical journal 20010815
Synergism between base excision repair, mediated by the DNA glycosylases Ntg1 and Ntg2, and nucleotide excision repair in the removal of oxidatively damaged DNA bases in Saccharomyces cerevisiae. Molecular genetics and genomics : MGG 20010801
Species/variety differences in biochemical composition and nutritional value of Indian tribal legumes of the genus Canavalia. Die Nahrung 20010801
The timing of endothelin and nitric oxide inhibition affects survival in a mice model of septic shock. European journal of pharmacology 20010302
L-canavanine, a selective inhibitor of inducible NO synthase, increases plasma endothelin-1 concentrations in dogs with endotoxic shock. Journal of critical care 20010301
Quercetin, coenzyme Q10, and L-canavanine as protective agents against lipid peroxidation and nitric oxide generation in endotoxin-induced shock in rat brain. Pharmacological research 20010301
Role of nitric oxide in the synthesis of guanidinosuccinic acid, an activator of the N-methyl-D-aspartate receptor. Kidney international. Supplement 20010201
Effects of nitric oxide donors and nitric oxide synthase substrates on ciliary muscle contracted by carbachol and endothelin for possible use in myopia prevention. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010201
Inducible and neuronal nitric oxide synthase involvement in lipopolysaccharide-induced sphincteric dysfunction. American journal of physiology. Gastrointestinal and liver physiology 20010101
Possible role of nitric oxide and mast cells in endotoxin-induced cardioprotection. Pharmacological research 20010101
Plant growth inhibitory activity of L-canavanine and its mode of action. Journal of chemical ecology 20010101
Characterization of Rheb functions using yeast and mammalian systems. Methods in enzymology 20010101
Effects of gold banded lily (Lilium auratum Lindl) or Chinese milk vetch (Astragalus sinicus L) on spontaneous mammary tumourigenesis in SHN mice. Anticancer research 20010101
L-Canavanine: a higher plant insecticidal allelochemical. Amino acids 20010101
Recombinant cell lines for stress reporter assays. Cell biology and toxicology 20010101
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