5,6-Dihydroxy-1h-indole-2-carboxylic acid
Title | Journal |
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The eumelanin intermediate 5,6-dihydroxyindole-2-carboxylic acid is a messenger in the cross-talk among epidermal cells. | The Journal of investigative dermatology 20120401 |
Topical hypopigmenting agents for pigmentary disorders and their mechanisms of action. | Annals of dermatology 20120201 |
The action of D-dopachrome tautomerase as an adipokine in adipocyte lipid metabolism. | PloS one 20120101 |
Multiple tyrosine metabolites are GPR35 agonists. | Scientific reports 20120101 |
New insights into the evolution of metazoan tyrosinase gene family. | PloS one 20120101 |
Melanin-based coatings as lead-binding agents. | Bioinorganic chemistry and applications 20120101 |
A complex genomic rearrangement involving the endothelin 3 locus causes dermal hyperpigmentation in the chicken. | PLoS genetics 20111201 |
UV-absorption spectra of melanosomes containing varying 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid content. | The journal of physical chemistry. B 20111103 |
Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation. | PLoS genetics 20110901 |
Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic. | PLoS genetics 20110901 |
Maintenance of immune hyporesponsiveness to melanosomal proteins by DHICA-mediated antioxidation: Possible implications for autoimmune vitiligo. | Free radical biology & medicine 20110501 |
Is DHICA the key to dopachrome tautomerase and melanocyte functions? | Pigment cell & melanoma research 20110201 |
Original article title: 'Comparison of therapeutic efficacy of topical corticosteroid and oral zinc sulfate-topical corticosteroid combination in the treatment of vitiligo patients: a clinical trial'. | BMC dermatology 20110101 |
Ethnic and mouse strain differences in central corneal thickness and association with pigmentation phenotype. | PloS one 20110101 |
Complex interactions of Tyrp1 in the eye. | Molecular vision 20110101 |
Hypothesis: zinc can be effective in treatment of vitiligo. | Indian journal of dermatology 20110101 |
UV-dissipation mechanisms in the eumelanin building block DHICA. | Chemphyschem : a European journal of chemical physics and physical chemistry 20100802 |
Elevated oxidative membrane damage associated with genetic modifiers of Lyst-mutant phenotypes. | PLoS genetics 20100701 |
Regulation of DHICA-mediated antioxidation by dopachrome tautomerase: implication for skin photoprotection against UVA radiation. | Free radical biology & medicine 20100501 |
Direct measurement of the ultraviolet absorption coefficient of single retinal melanosomes. | Photochemistry and photobiology 20100101 |
Spectrum of candidate gene mutations associated with Indian familial oculocutaneous and ocular albinism. | Molecular vision 20100101 |
Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology. | Human genomics and proteomics : HGP 20100101 |
Mechanisms regulating skin pigmentation: the rise and fall of complexion coloration. | International journal of molecular sciences 20090901 |
An updated review of tyrosinase inhibitors. | International journal of molecular sciences 20090601 |
Lack of visible chromophore development in the pulse radiolysis oxidation of 5,6-dihydroxyindole-2-carboxylic acid oligomers: DFT investigation and implications for eumelanin absorption properties. | The Journal of organic chemistry 20090515 |
Structural, electrical, electronic and optical properties of melanin films. | The European physical journal. E, Soft matter 20090301 |
Physico-chemical evaluation of rationally designed melanins as novel nature-inspired radioprotectors. | PloS one 20090101 |
Study of total antioxidant status and glutathione peroxidase activity in Tunisian vitiligo patients. | Indian journal of dermatology 20090101 |
Role of solvent, pH, and molecular size in excited-state deactivation of key eumelanin building blocks: implications for melanin pigment photostability. | Journal of the American Chemical Society 20081217 |
Effect of dimerization on vibrational spectra of eumelanin precursors. | Photochemistry and photobiology 20080101 |
Solvochromic effects in model eumelanin compounds. | Photochemistry and photobiology 20080101 |
Synthesis and polymerization studies of organic-soluble eumelanins. | Photochemistry and photobiology 20080101 |
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone. | Photochemistry and photobiology 20080101 |
Computational systems analysis of dopamine metabolism. | PloS one 20080101 |
Parasite suppression of the oxidations of eumelanin precursors in Drosophila melanogaster. | Archives of insect biochemistry and physiology 20071001 |
Changes of melanosome morphology associated with the differentiation of epidermal melanocytes in slaty mice. | Anatomical record (Hoboken, N.J. : 2007) 20070801 |
Transition dipole strength of eumelanin. | Physical review. E, Statistical, nonlinear, and soft matter physics 20070801 |
Convergent proton-transfer photocycles violate mirror-image symmetry in a key melanin monomer. | Journal of the American Chemical Society 20070530 |
Evaluation of efficacy and safety of rucinol serum in patients with melasma: a randomized controlled trial. | The British journal of dermatology 20070501 |
Evolution of pigment synthesis pathways by gene and genome duplication in fish. | BMC evolutionary biology 20070101 |
Ionizing radiation changes the electronic properties of melanin and enhances the growth of melanized fungi. | PloS one 20070101 |
Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes. | BMC cancer 20070101 |
Multiple splice variants within the bovine silver homologue (SILV) gene affecting coat color in cattle indicate a function additional to fibril formation in melanophores. | BMC genomics 20070101 |
Oculocutaneous albinism. | Orphanet journal of rare diseases 20070101 |
Hyperbranched molecular structures with potential antiviral activity: derivatives of 5,6-dihydroxyindole-2-carboxylic Acid. | Molecules (Basel, Switzerland) 20061218 |
Synthesis, discovery and mechanism of 2,6-dimethoxy-N-(4-methoxyphenyl)benzamide as potent depigmenting agent in the skin. | Biochemical and biophysical research communications 20061013 |
Dopaquinone redox exchange with dihydroxyindole and dihydroxyindole carboxylic acid. | Pigment cell research 20061001 |
Characterization of the pigment produced by the planarian, Dugesia ryukyuensis. | Pigment cell research 20060601 |
Fe(III)-coordination properties of neuromelanin components: 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid. | Inorganic chemistry 20060501 |
Chemical and structural disorder in eumelanins: a possible explanation for broadband absorbance. | Biophysical journal 20060201 |
Functional amyloid formation within mammalian tissue. | PLoS biology 20060101 |
Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma. | BMC biology 20060101 |
Quantitative fluorescence excitation spectra of synthetic eumelanin. | The journal of physical chemistry. B 20051103 |
An oxygen transporter hemocyanin can act on the late pathway of melanin synthesis. | Pigment cell research 20050601 |
Metal-ion interactions and the structural organization of Sepia eumelanin. | Pigment cell research 20050201 |
Comparisons of the structural and chemical properties of melanosomes isolated from retinal pigment epithelium, iris and choroid of newborn and mature bovine eyes. | Photochemistry and photobiology 20050101 |
[UV-vis spectroscopic study of the effect of Cu(II) ions on dopachrome]. | Guang pu xue yu guang pu fen xi = Guang pu 20040701 |
Design and synthesis of novel dihydroxyindole-2-carboxylic acids as HIV-1 integrase inhibitors. | Antiviral chemistry & chemotherapy 20040301 |
Benzylamide derivative compound attenuates the ultraviolet B-induced hyperpigmentation in the brownish guinea pig skin. | Biochemical pharmacology 20040215 |
Involvement of photooxidation of melanogenic precursors in prolonged pigmentation induced by ultraviolet A. | The Journal of investigative dermatology 20040201 |
Changes in the proliferation and differentiation of neonatal mouse pink-eyed dilution melanocytes in the presence of excess tyrosine. | Pigment cell research 20031201 |
Aluminum ions accelerated the oxidative stress of copper-mediated melanin formation. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20031101 |
Skin-lightening products revisited. | International journal of cosmetic science 20030801 |
Effect of aluminum (III) on the conversion of dopachrome in the melanin synthesis pathway. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030601 |
The IFPCS presidential lecture: a chemist's view of melanogenesis. | Pigment cell research 20030601 |
Cocaine, benzoylecgonine, amphetamine, and N-acetylamphetamine binding to melanin subtypes. | Journal of analytical toxicology 20030401 |
Stimulation of the proliferation and differentiation of mouse pink-eyed dilution epidermal melanocytes by excess tyrosine in serum-free primary culture. | Journal of cellular physiology 20020501 |
Comparative biochemistry of eumelanogenesis and the protective roles of phenoloxidase and melanin in insects. | Pigment cell research 20020201 |
Tyrp1 and oculocutaneous albinism type 3. | Pigment cell research 20011201 |
Variation in melanin content and composition in type V and VI photoexposed and photoprotected human skin: the dominant role of DHI. | Pigment cell research 20011001 |
Relationship of melanin degradation products to actual melanin content: application to human hair. | Analytical biochemistry 20010301 |
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase. | The Biochemical journal 20010215 |
Interaction of major coat color gene functions in mice as studied by chemical analysis of eumelanin and pheomelanin. | Pigment cell research 20010201 |
Melanogenesis by tyrosinase action on 3,4-dihydroxyphenylalanine (DOPA) in the presence of polyethylene glycol: a matrix-assisted laser desorption/ionization mass spectrometric investigation. | Rapid communications in mass spectrometry : RCM 20010101 |