17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate
Title | Journal |
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An in vitro approach for prioritization and evaluation of chemical effects on glucocorticoid receptor mediated adipogenesis. | Toxicology and applied pharmacology 20180915 |
Novel Pathways of Endocrine Disruption Through Pesticides Interference With Human Mineralocorticoid Receptors. | Toxicological sciences : an official journal of the Society of Toxicology 20180301 |
Activation of intestinal GR-FXR and PPARα-UGT signaling exacerbates ibuprofen-induced enteropathy in mice. | Archives of toxicology 20180301 |
Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity. | Reproductive toxicology (Elmsford, N.Y.) 20180101 |
Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | Chemical research in toxicology 20150518 |
Spironolactone decreases the somatic signs of opiate withdrawal by blocking the mineralocorticoid receptors (MR). | Toxicology 20141204 |
Aldosterone activates transcription factor Nrf2 in kidney cells both in vitro and in vivo. | Antioxidants & redox signaling 20141120 |
Aldosterone induces fibrosis, oxidative stress and DNA damage in livers of male rats independent of blood pressure changes. | Toxicology and applied pharmacology 20141101 |
Identification of (R)-6-(1-(4-cyano-3-methylphenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl)-2-methoxynicotinic acid, a highly potent and selective nonsteroidal mineralocorticoid receptor antagonist. | Journal of medicinal chemistry 20140522 |
Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action. | PloS one 20140101 |
Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). | Toxicological sciences : an official journal of the Society of Toxicology 20131201 |
A study comparing the efficacy of antimicrobial agents versus enzyme (P-gp) inducers in the treatment of 2,4,6 trinitrobenzenesulfonic acid-induced colitis in rats. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20130801 |
Dexamethasone induces caveolin-1 in vascular endothelial cells: implications for attenuated responses to VEGF. | American journal of physiology. Cell physiology 20130415 |
Downregulation of the cardiotrophin-1 gene expression by valsartan and spironolactone in hypertrophied heart rats in vivo and rat cardiomyocyte H9c2 cell line in vitro: a novel mechanism of cardioprotection. | Journal of cardiovascular pharmacology 20130401 |
Prostate effect in dogs with the aldosterone receptor blocker eplerenone. | Toxicologic pathology 20130201 |
Quality of life in patients with primary aldosteronism: gender differences in untreated and long-term treated patients and associations with treatment and aldosterone. | Journal of psychiatric research 20121201 |
Permanent muscular sodium overload and persistent muscle edema in Duchenne muscular dystrophy: a possible contributor of progressive muscle degeneration. | Journal of neurology 20121101 |
Permanent scalp alopecia related to breast cancer chemotherapy by sequential fluorouracil/epirubicin/cyclophosphamide (FEC) and docetaxel: a prospective study of 20 patients. | Annals of oncology : official journal of the European Society for Medical Oncology 20121101 |
Hyperkalaemia in the age of aldosterone antagonism. | QJM : monthly journal of the Association of Physicians 20121101 |
Establishment of cocrystal cocktail grinding method for rational screening of pharmaceutical cocrystals. | International journal of pharmaceutics 20121101 |
Biologic drugs in autoinflammatory syndromes. | Autoimmunity reviews 20121101 |
Mineralocorticoid receptor blocker eplerenone reduces pain behaviors in vivo and decreases excitability in small-diameter sensory neurons from local inflamed dorsal root ganglia in vitro. | Anesthesiology 20121101 |
[Is eplerenone nephrotoxic?]. | Deutsche medizinische Wochenschrift (1946) 20121101 |
Corticosterone suppresses the proliferation of BV2 microglia cells via glucocorticoid, but not mineralocorticoid receptor. | Life sciences 20121022 |
Usefulness of matrix metalloproteinase-9 plasma levels to identify patients with preserved left ventricular systolic function after acute myocardial infarction who could benefit from eplerenone. | The American journal of cardiology 20121015 |
Effect of metformin and spironolactone therapy on OGTT in patients with polycystic ovarian syndrome - a retrospective analysis. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20121001 |
Bone involvement in aldosteronism. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20121001 |
Palmitate increases the susceptibility of cells to drug-induced toxicity: an in vitro method to identify drugs with potential contraindications in patients with metabolic disease. | Toxicological sciences : an official journal of the Society of Toxicology 20121001 |
Aldosterone receptor antagonists in cardiovascular disease: a review of the recent literature and insight into potential future indications. | Clinical cardiology 20121001 |
Differential ubiquitylation of the mineralocorticoid receptor is regulated by phosphorylation. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20121001 |
Blockade of mineralocorticoid receptors enhances naïve T-helper cell counts during early sleep in humans. | Brain, behavior, and immunity 20121001 |
Persistent hypertension after adrenalectomy for an aldosterone-producing adenoma: weight as a critical prognostic factor for aldosterone's lasting effect on the cardiac and vascular systems. | The Journal of surgical research 20121001 |
A novel mutation in the interleukin-1 receptor antagonist associated with intrauterine disease onset. | Clinical immunology (Orlando, Fla.) 20121001 |
Effects of angiogenesis inhibition by spironolactone on isolated vas deferens contractility in an experimental varicocele model in rats. | Urology 20121001 |
Overlapping spironolactone dosing in primary aldosteronism and resistant essential hypertension. | Journal of clinical hypertension (Greenwich, Conn.) 20121001 |
[Gitelman syndrome in pregnancy--a severe hypokalemia with favorable perinatal prognosis]. | Ceska gynekologie 20121001 |
Mineralocorticoid receptor antagonists for the treatment of hypertension and diabetic nephropathy. | Journal of medicinal chemistry 20120927 |
Rapid, dynamic changes in glomerular permeability to macromolecules during systemic angiotensin II (ANG II) infusion in rats. | American journal of physiology. Renal physiology 20120915 |
Novel β-amino acid derivatives as inhibitors of cathepsin A. | Journal of medicinal chemistry 20120913 |
[2 promising substances for diastolic heart failure]. | MMW Fortschritte der Medizin 20120910 |
Left ventricular failure due to a rare variant of congenital adrenal hyperplasia. | Indian journal of pediatrics 20120901 |
The effects of 2 mg chlormadinone acetate/30 mcg ethinylestradiol, alone or combined with spironolactone, on cardiovascular risk markers in women with polycystic ovary syndrome. | Contraception 20120901 |
Eplerenone inhibits aldosterone-induced renal expression of cyclooxygenase. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20120901 |
A diastereoselective synthesis of 7α-nitromethyl steroid derivative and its use for an efficient synthesis of eplerenone. | Steroids 20120901 |
Mechanisms involved in BACE upregulation associated to stress. | Current Alzheimer research 20120901 |
Development and validation of a stability-indicating HPLC assay method for simultaneous determination of spironolactone and furosemide in tablet formulation. | Journal of chromatographic science 20120901 |
Positive effect of eplerenone treatment on endothelial progenitor cells in patients with chronic heart failure. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20120901 |
Polymorphic variation of CYP11B2 predicts postoperative resolution of hypertension in patients undergoing adrenalectomy for aldosterone-producing adenomas. | International journal of urology : official journal of the Japanese Urological Association 20120901 |
Effects of spironolactone alone and in addition to a β-blocker on myocardial histological and electrical remodeling in chronic severe failing rat hearts. | Journal of cardiovascular pharmacology 20120901 |
Beneficial effect of ivabradine in dilated cardiomyopathy from Becker muscular dystrophy. | Herz 20120901 |
Failure to downregulate the epithelial sodium channel causes salt sensitivity in Hsd11b2 heterozygote mice. | Hypertension (Dallas, Tex. : 1979) 20120901 |
Ranolazine-induced severe bladder hypotonia. | The Annals of pharmacotherapy 20120901 |
Drug-induced gynecomastia: an evidence-based review. | Expert opinion on drug safety 20120901 |
The role of aldosterone receptor antagonists in the management of heart failure: an update. | Cleveland Clinic journal of medicine 20120901 |
Community care in England: reducing socioeconomic inequalities in heart failure. | Circulation 20120828 |
Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension. | Circulation 20120821 |
Long-term effects of aldosterone blockade in resistant hypertension associated with chronic kidney disease. | Journal of human hypertension 20120801 |
Role of mineralocorticoid receptor/Rho/Rho-kinase pathway in obesity-related renal injury. | International journal of obesity (2005) 20120801 |
Spironolactone diminishes urinary albumin excretion in patients with type 1 diabetes and microalbuminuria: a randomized placebo-controlled crossover study. | Diabetic medicine : a journal of the British Diabetic Association 20120801 |
Mineralocorticoid receptors mediate cardiac remodelling in morphine-dependent rats. | Basic & clinical pharmacology & toxicology 20120801 |
17-Hydroxysteroid dehydrogenase type 5 gene polymorphism (-71A/G HSD17B5 SNP) and treatment with oral contraceptive pills in PCOS women without metabolic comorbidities. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20120801 |
Exposure to trimethoprim-sulfamethoxazole is associated with hospitalisation for hyperkalaemia in older people treated with spironolactone. | Evidence-based medicine 20120801 |
Spironolactone, but not eplerenone, impairs glucose tolerance in a rat model of metabolic syndrome. | The Journal of veterinary medical science 20120801 |
Recovery from ischemic acute kidney injury by spironolactone administration. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120801 |
Additive amelioration of oxidative stress and cardiac function by combined mineralocorticoid and angiotensin receptor blockers in postinfarct failing hearts. | Journal of cardiovascular pharmacology 20120801 |
Eplerenone and new-onset diabetes in patients with mild heart failure: results from the Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure (EMPHASIS-HF). | European journal of heart failure 20120801 |
T-type Ca²⁺ signalling downregulates MEK1/2 phosphorylation and cross-talk with the RAAS transcriptional response in cardiac myocytes. | Journal of molecular and cellular cardiology 20120801 |
A case-control study of determinants for the occurrence of gouty arthritis in heart failure patients. | European journal of heart failure 20120801 |
Sequential nephron blockade versus sequential renin-angiotensin system blockade in resistant hypertension: a prospective, randomized, open blinded endpoint study. | Journal of hypertension 20120801 |
Spironolactone prevents chlorthalidone-induced sympathetic activation and insulin resistance in hypertensive patients. | Hypertension (Dallas, Tex. : 1979) 20120801 |
Treatment of diastolic dysfunction in hypertension. | Nutrition, metabolism, and cardiovascular diseases : NMCD 20120801 |
Eplerenone, an aldosterone blocker, is more effective in reducing blood pressure in patients with, than without, metabolic syndrome. | Therapeutic advances in cardiovascular disease 20120801 |
The effect of spironolactone on ventricular tachyarrhythmias in patients with implantable cardioverter-defibrillators. | Circulation. Arrhythmia and electrophysiology 20120801 |
Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseases. | ChemMedChem 20120801 |
Eplerenone is not superior to older and less expensive aldosterone antagonists. | The American journal of medicine 20120801 |
[Spironolactone inhibits hepatic sinusoid angiogenesis in rats with hepatic fibrosis]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120801 |
A novel C,D-spirolactone analogue of paclitaxel: autophagy instead of apoptosis as a previously unknown mechanism of cytotoxic action for taxoids. | Organic & biomolecular chemistry 20120707 |
Ligand-controlled iron-catalyzed coupling of α-substituted β-ketoesters with phenols. | Organic letters 20120706 |
Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy. | The Journal of clinical investigation 20120702 |
Spironolactone and colitis: increased mortality in rodents and in humans. | Inflammatory bowel diseases 20120701 |
Diosgenin promotes oligodendrocyte progenitor cell differentiation through estrogen receptor-mediated ERK1/2 activation to accelerate remyelination. | Glia 20120701 |
Obesity and oxidative stress predict AKI after cardiac surgery. | Journal of the American Society of Nephrology : JASN 20120701 |
The mineralocorticoid receptor-p38MAPK-NFκB or ERK-Sp1 signal pathways mediate aldosterone-stimulated inflammatory and profibrotic responses in rat vascular smooth muscle cells. | Acta pharmacologica Sinica 20120701 |
The 2012 ESC Guidelines on Heart Failure. | European heart journal 20120701 |
Eplerenone for the treatment of cardiovascular disorders. | Expert review of cardiovascular therapy 20120701 |
Aldosterone antagonists and chronic aortic regurgitation: promising but not quite ready for prime time. | The Journal of heart valve disease 20120701 |
Potentially modifiable biological targets in aortic regurgitation. | The Journal of heart valve disease 20120701 |
Effects of spironolactone treatment on an experimental model of chronic aortic valve regurgitation. | The Journal of heart valve disease 20120701 |
The meaning of hypokalemia in heart failure. | International journal of cardiology 20120628 |
Dramatic influence of the substitution of alkylidene-5H-furan-2-ones in Diels-Alder cycloadditions with o-quinonedimethide as diene partner: en route to the CDEF polycyclic ring system of lactonamycin. | Organic & biomolecular chemistry 20120628 |
When the heart runs out of heartbeats: treatment options for refractory end-stage heart failure. | Circulation 20120612 |
Cyproterone acetate or drospirenone containing combined oral contraceptives plus spironolactone or cyproterone acetate for hirsutism: randomized comparison of three regimens. | The Journal of dermatological treatment 20120601 |
Liposome and niosome preparation using a membrane contactor for scale-up. | Colloids and surfaces. B, Biointerfaces 20120601 |
Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. | Experimental physiology 20120601 |
Transcription factor-mediated regulation of carboxylesterase enzymes in livers of mice. | Drug metabolism and disposition: the biological fate of chemicals 20120601 |
Interleukin 1 receptor antagonist deficiency presenting as infantile pustulosis mimicking infantile pustular psoriasis. | Archives of dermatology 20120601 |
Angiotensin II- and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation. | Journal of the American Society of Nephrology : JASN 20120601 |
The conversion of oridonin to spirolactone-type or enmein-type diterpenoid: synthesis and biological evaluation of ent-6,7-seco-oridonin derivatives as novel potential anticancer agents. | European journal of medicinal chemistry 20120601 |
Low-dose spironolactone prevents apoptosis repressor with caspase recruitment domain degradation during myocardial infarction. | Hypertension (Dallas, Tex. : 1979) 20120601 |
Aldosterone inhibits antifibrotic factors in mouse hypertensive heart. | Hypertension (Dallas, Tex. : 1979) 20120601 |
Rationale and design of ARTS: a randomized, double-blind study of BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease. | European journal of heart failure 20120601 |
Hypo- and hyperglycemia predict outcome in patients with left ventricular dysfunction after acute myocardial infarction: data from EPHESUS. | Journal of cardiac failure 20120601 |
Post-adolescent acne in women: more common and more clinical considerations. | Journal of drugs in dermatology : JDD 20120601 |
Safety of mineralocorticoid receptor antagonists in patients receiving hemodialysis. | The Annals of pharmacotherapy 20120601 |
[Frequency of hypertension resistant to treatment and indication for renal denervation]. | Annales de cardiologie et d'angeiologie 20120601 |
[Use of antihypertensive drugs in France and relationship with cardiovascular disease. FLAHS 2009-2010 surveys]. | Annales de cardiologie et d'angeiologie 20120601 |
Aldosterone-producing adrenocortical carcinoma without hypertension. | The Korean journal of internal medicine 20120601 |
[An abdominal CT scan in first-line is an efficient investigation of uncontrolled hypertensives suspected to have an adrenal cause]. | Annales de cardiologie et d'angeiologie 20120601 |
Recent developments in the management of heart failure. | The Practitioner 20120601 |
Gitelman syndrome. | BMJ (Clinical research ed.) 20120529 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | Journal of medicinal chemistry 20120524 |
Genes implicated in insulin resistance are down-regulated in primary aldosteronism patients. | Molecular and cellular endocrinology 20120515 |
Cardiac complications associated with trastuzumab in the setting of adjuvant chemotherapy for breast cancer overexpressing human epidermal growth factor receptor type 2 - a prospective study. | Archives of medical science : AMS 20120509 |
Mechanisms underlying the diuretic effects of Tropaeolum majus L. extracts and its main component isoquercitrin. | Journal of ethnopharmacology 20120507 |
Changes in cortisol secretion during antidepressive treatment and cognitive improvement in patients with major depression: a longitudinal study. | Psychoneuroendocrinology 20120501 |
Two cases of male nipple leiomyoma: idiopathic leiomyoma and gynecomastia-associated leiomyoma. | The American Journal of dermatopathology 20120501 |
SM-368229, a novel promising mineralocorticoid receptor antagonist, shows antihypertensive efficacy with minimal effect on serum potassium level in rats. | Journal of cardiovascular pharmacology 20120501 |
Emphysema in an adult with galactosialidosis linked to a defect in primary elastic fiber assembly. | Molecular genetics and metabolism 20120501 |
Polycystic ovary syndrome: Implications of measurement of plasma aldosterone, renin activity and progesterone. | Steroids 20120501 |
Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100. | Cancer research 20120501 |
Male pseudohermaphroditism presented with sudden cardiac arrest. | Yonsei medical journal 20120501 |
Resistant hypertension and aldosterone: an update. | The Canadian journal of cardiology 20120501 |
Therapeutic challenges and management of heart failure during pregnancy (part I). | Medical science monitor : international medical journal of experimental and clinical research 20120501 |
Eplerenone and atrial fibrillation in mild systolic heart failure: results from the EMPHASIS-HF (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure) study. | Journal of the American College of Cardiology 20120501 |
Expert consensus: Renal denervation for the treatment of hypertension. | Diagnostic and interventional imaging 20120501 |
A rare case of primary hyperparathyroidism associated with primary aldosteronism, Hürthle cell thyroid cancer and meningioma. | Journal of Korean medical science 20120501 |
A prospective double-blind randomized placebo-controlled clinical trial to evaluate the safety and efficacy of spironolactone in patients with advanced congestive heart failure on continuous ambulatory peritoneal dialysis. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20120501 |
Cost-effectiveness of aldosterone antagonists for the treatment of post-myocardial infarction heart failure. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20120501 |
Clinically insignificant negative interferences of spironolactone, potassium canrenoate, and their common metabolite canrenone in new dimension vista LOCI digoxin immunoassay. | Journal of clinical laboratory analysis 20120501 |
Rationale for treating oedema in Duchenne muscular dystrophy with eplerenone. | Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 20120501 |
Molecular pathways: digoxin use and estrogen-sensitive cancers--risks and possible therapeutic implications. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120415 |
[Liquorice-induced hypertension and hypokalaemia]. | Ugeskrift for laeger 20120409 |
Deficiency of interleukin-1-receptor antagonist syndrome: a rare auto-inflammatory condition that mimics multiple classic radiographic findings. | Pediatric radiology 20120401 |
Spontaneous remission of idiopathic aldosteronism after long-term treatment with spironolactone: results from the German Conn's Registry. | Clinical endocrinology 20120401 |
Gitelman syndrome: novel mutation and long-term follow-up. | Clinical and experimental nephrology 20120401 |
Aliskiren-associated acute kidney injury in a patient with pre-existing chronic kidney disease and dilated cardiomyopathy. | Clinical and experimental nephrology 20120401 |
A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures. | Molecular psychiatry 20120401 |
Dexamethasone stimulates endothelin-1 gene expression in renal collecting duct cells. | Steroids 20120401 |
Aldosterone inhibits endothelial morphogenesis and angiogenesis through the downregulation of vascular endothelial growth factor receptor-2 expression subsequent to peroxisome proliferator-activated receptor gamma. | The Journal of steroid biochemistry and molecular biology 20120401 |
Activation of mineralocorticoid receptors in the rostral ventrolateral medulla is involved in hypertensive mechanisms in stroke-prone spontaneously hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20120401 |
Sex-specific effects of spironolactone on blood pressure in gonadectomized male and female Wistar rats. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20120401 |
Unilateral primary aldosteronism with spontaneous remission after long-term spironolactone therapy. | The Journal of clinical endocrinology and metabolism 20120401 |
The role of mineralocorticoid receptor antagonists in patients with American College of Cardiology/American Heart Association stage B heart failure. | Heart failure clinics 20120401 |
A simplified mechanistic algorithm for treating resistant hypertension: efficacy in a retrospective study. | Journal of clinical hypertension (Greenwich, Conn.) 20120401 |
Update on aldosterone antagonists use in heart failure with reduced left ventricular ejection fraction. Heart Failure Society of America Guidelines Committee. | Journal of cardiac failure 20120401 |
Scurvy in an alcoholic malnourished cirrhotic man with spontaneous bacterial peritonitis. | Clinics (Sao Paulo, Brazil) 20120401 |
Effect of eplerenone, a selective aldosterone blocker, on the development of diabetic nephropathy in type 2 diabetic rats. | Diabetes & metabolism journal 20120401 |
Beneficial role of spironolactone, telmisartan and their combination on isoproterenol-induced cardiac hypertrophy. | Acta cardiologica 20120401 |
Molecular pharmacology of the mineralocorticoid receptor: prospects for novel therapeutics. | Molecular and cellular endocrinology 20120324 |
Activation of renal angiotensin type 1 receptor contributes to the pathogenesis of progressive renal injury in a rat model of chronic cardiorenal syndrome. | American journal of physiology. Renal physiology 20120315 |
Pregnane X receptor regulates drug metabolism and transport in the vasculature and protects from oxidative stress. | Cardiovascular research 20120315 |
Opposing roles of glucocorticoid receptor and mineralocorticoid receptor in trimethyltin-induced cytotoxicity in the mouse hippocampus. | Neuroscience letters 20120309 |
Contribution of glucocorticoid-mineralocorticoid receptor pathway on the obesity-related adipocyte dysfunction. | Biochemical and biophysical research communications 20120309 |
Letter by Fayssoil regarding article, 'Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice'. | Circulation 20120306 |
Management of refractory ascites. | American journal of therapeutics 20120301 |
The long-term antiproteinuric effect of eplerenone, a selective aldosterone blocker, in patients with non-diabetic chronic kidney disease. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301 |
Improvement of cognitive impairment in female type 2 diabetes mellitus mice by spironolactone. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301 |
Long-term mineralocorticoid receptor blockade ameliorates progression of experimental diabetic renal disease. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120301 |
The safety and tolerability of spironolactone in patients with mild to moderate chronic kidney disease. | British journal of clinical pharmacology 20120301 |
Spironolactone improves nephropathy by enhancing glucose-6-phosphate dehydrogenase activity and reducing oxidative stress in diabetic hypertensive rat. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301 |
Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice. | American journal of hypertension 20120301 |
Factors affecting the aldosterone/renin ratio. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20120301 |
Frequency and predictors of hyperkalemia in patients ≥60 years of age with heart failure undergoing intense medical therapy. | The American journal of cardiology 20120301 |
Activation of the aldosterone/mineralocorticoid receptor system and protective effects of mineralocorticoid receptor antagonism in retinal ischemia-reperfusion injury. | Experimental eye research 20120301 |
Dietary salt modulates the sodium chloride cotransporter expression likely through an aldosterone-mediated WNK4-ERK1/2 signaling pathway. | Pflugers Archiv : European journal of physiology 20120301 |
Stress and corticosteroid modulation of seizures and synaptic inhibition in the hippocampus. | Experimental neurology 20120301 |
Antiapolipoprotein A-1 IgG chronotropic effects require nongenomic action of aldosterone on L-type calcium channels. | Endocrinology 20120301 |
Immunology in clinic review series; focus on autoinflammatory diseases: update on monogenic autoinflammatory diseases: the role of interleukin (IL)-1 and an emerging role for cytokines beyond IL-1. | Clinical and experimental immunology 20120301 |
[Renal function in patients with heart failure: prognostic value]. | Revista clinica espanola 20120301 |
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone. | Clinics in perinatology 20120301 |
Predictive factors of left ventricular mass changes after treatment of primary aldosteronism. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20120301 |
Menopause management: how you can do better. | The Journal of family practice 20120301 |
Incidence, clinical predictors, and prognostic impact of worsening renal function in elderly patients with chronic heart failure on intensive medical therapy. | American heart journal 20120301 |
Bleeding from ruptured oesophageal varices: propranolol for primary prevention. | Prescrire international 20120301 |
DIRA, DITRA, and new insights into pathways of skin inflammation: what's in a name? | Archives of dermatology 20120301 |
[Clinical analysis of 17 cases of Gitelman syndrome]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120301 |
Amino acid and vitamin supplementation improved health conditions in elderly participants. | Journal of clinical biochemistry and nutrition 20120301 |
Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011 (part 2). | Journal of cachexia, sarcopenia and muscle 20120301 |
Assessment of the heart failure pharmacotherapy of patients with continuous flow left-ventricular assist devices. | The International journal of artificial organs 20120301 |
Oral Spironolactone in Post-teenage Female Patients with Acne Vulgaris: Practical Considerations for the Clinician Based on Current Data and Clinical Experience. | The Journal of clinical and aesthetic dermatology 20120301 |
Revision and update on clinical practice guideline for liver cirrhosis. | The Korean journal of hepatology 20120301 |
Effect of spironolactone on ventricular arrhythmias in patients with left ventricular systolic dysfunction and implantable cardioverter defibrillators. | Indian heart journal 20120301 |
Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases. | Archives of medical science : AMS 20120227 |
Yaoshanenolides A and B: new spirolactones from the bark of Machilus yaoshansis. | Organic letters 20120217 |
Comparison of the efficacy of 5% topical spironolactone gel and placebo in the treatment of mild and moderate acne vulgaris: a randomized controlled trial. | The Journal of dermatological treatment 20120201 |
Pharmacotherapy of polycystic ovary syndrome--an update. | Fundamental & clinical pharmacology 20120201 |
Potential drug-drug interactions and adverse drug reactions in patients with liver cirrhosis. | European journal of clinical pharmacology 20120201 |
In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions. | Pharmaceutical research 20120201 |
Protective effects of mineralocorticoid receptor blockade against neuropathy in experimental diabetic rats. | Diabetes, obesity & metabolism 20120201 |
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate. | Neurochemical research 20120201 |
Aldosterone stimulates nuclear factor-kappa B activity and transcription of intercellular adhesion molecule-1 and connective tissue growth factor in rat mesangial cells via serum- and glucocorticoid-inducible protein kinase-1. | Clinical and experimental nephrology 20120201 |
Eplerenone use in primary aldosteronism during pregnancy. | Hypertension (Dallas, Tex. : 1979) 20120201 |
Action of ANP on the nongenomic dose-dependent biphasic effect of aldosterone on NHE1 in proximal S3 segment. | The Journal of steroid biochemistry and molecular biology 20120201 |
Aldosterone induces vascular insulin resistance by increasing insulin-like growth factor-1 receptor and hybrid receptor. | Arteriosclerosis, thrombosis, and vascular biology 20120201 |
Mineralocorticoid receptor blocker eplerenone improves endothelial function and inhibits Rho-associated kinase activity in patients with hypertension. | Clinical pharmacology and therapeutics 20120201 |
A case of severe aortic valve regurgitation caused by an ascending aortic aneurysm in a young patient with autosomal dominant polycystic kidney disease and normal renal function. | Korean circulation journal 20120201 |
Irritable bowel syndrome and drospirenone-containing oral contraceptives; a comparative-safety study. | Current drug safety 20120201 |
Determinants and consequences of renal function variations with aldosterone blocker therapy in heart failure patients after myocardial infarction: insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study. | Circulation 20120117 |
Differential involvement of amygdala corticosteroid receptors in visceral hyperalgesia following acute or repeated stress. | American journal of physiology. Gastrointestinal and liver physiology 20120115 |
Spontaneous remission of nephrotic syndrome in membranous nephropathy with chronic renal impairment. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120101 |
The effect of treatment on monocyte and lymphocyte cytokine release in patients with aldosteronoma. | Hypertension research : official journal of the Japanese Society of Hypertension 20120101 |
Could mineralocorticoids play a role in the pathophysiology of open angle glaucoma? | Journal of ophthalmology 20120101 |
The win ratio: a new approach to the analysis of composite endpoints in clinical trials based on clinical priorities. | European heart journal 20120101 |
Comparison of electrospun and extruded Soluplus®-based solid dosage forms of improved dissolution. | Journal of pharmaceutical sciences 20120101 |
Bradykinin type-2 receptor expression correlates with age and is subjected to transcriptional regulation. | International journal of vascular medicine 20120101 |
Surgical management of primary aldosteronism. not everything that shines is gold. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20120101 |
Extending the phenotypic spectrum of keratitis-ichthyosis-deafness syndrome: report of a patient with GJB2 (G12R) Connexin 26 mutation and unusual clinical findings. | Pediatric dermatology 20120101 |
The number of leads with fragmented QRS is independently associated with cardiac death or hospitalization for heart failure in patients with prior myocardial infarction. | Journal of cardiology 20120101 |
Acute glucocorticoid administration rapidly suppresses basal and stress-induced hypothalamo-pituitary-adrenal axis activity. | Endocrinology 20120101 |
Chronic social defeat up-regulates expression of norepinephrine transporter in rat brains. | Neurochemistry international 20120101 |
PEARL-HF: prevention of hyperkalemia in patients with heart failure using a novel polymeric potassium binder, RLY5016. | Future cardiology 20120101 |
Endogenous aldosterone is involved in vascular calcification in rat. | Experimental biology and medicine (Maywood, N.J.) 20120101 |
The 'obesity paradox': does it persist among Israeli patients with decompensated heart failure? A subanalysis of the Heart Failure Survey in Israel (HFSIS). | Journal of cardiac failure 20120101 |
Mineralocorticoid receptor-dependent proximal tubule injury is mediated by a redox-sensitive mTOR/S6K1 pathway. | American journal of nephrology 20120101 |
Eplerenone improved hypokalemia in a patient with Gitelman's syndrome. | Internal medicine (Tokyo, Japan) 20120101 |
The effect of combination treatment with aliskiren and blockers of the renin-angiotensin system on hyperkalaemia and acute kidney injury: systematic review and meta-analysis. | BMJ (Clinical research ed.) 20120101 |
The 5 alpha-reductase isozyme family: a review of basic biology and their role in human diseases. | Advances in urology 20120101 |
Refractory hypertension: definition, prevalence, and patient characteristics. | Journal of clinical hypertension (Greenwich, Conn.) 20120101 |
Interventions to enhance adherence to medications in patients with heart failure: a systematic review. | Circulation. Heart failure 20120101 |
Current pharmacologic approaches for prevention and treatment of bronchopulmonary dysplasia. | International journal of pediatrics 20120101 |
Effects of ACE-inhibitors and angiotensin receptor blockers on inflammation. | Current pharmaceutical design 20120101 |
The epidermal growth factor receptor is involved in angiotensin II but not aldosterone/salt-induced cardiac remodelling. | PloS one 20120101 |
Antihypertensive and cardiorenal protective effects of SM-368229, a novel mineralocorticoid receptor antagonist, in aldosterone/salt-treated rats. | Pharmacology 20120101 |
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing. | ALTEX 20120101 |
Assessing the necessity of chimpanzee experimentation. | ALTEX 20120101 |
Recent advancements in the treatment of resistant hypertension. | Postgraduate medicine 20120101 |
Evaluation and pharmacologic approach to patients with resistant hypertension. | Postgraduate medicine 20120101 |
Beta blocker use in subjects with type 2 diabetes mellitus and systolic heart failure does not worsen glycaemic control. | Cardiovascular diabetology 20120101 |
Neutrophil Gelatinase-Associated Lipocalin (NGAL) predicts renal injury in acute decompensated cardiac failure: a prospective observational study. | BMC cardiovascular disorders 20120101 |
Development of square-wave adsorptive stripping voltammetric method for determination of acebutolol in pharmaceutical formulations and biological fluids. | Chemistry Central journal 20120101 |
Evidence and consequences of the central role of the kidneys in the pathophysiology of sympathetic hyperactivity. | Frontiers in physiology 20120101 |
Spontaneous sinus conversion of permanent atrial fibrillation during treatment of hyperkalemia. | Korean circulation journal 20120101 |
Cardiovascular disease in kidney donors: matched cohort study. | BMJ (Clinical research ed.) 20120101 |
Variability of NT-proBNP and its relationship with inflammatory status in patients with stable essential hypertension: a 2-year follow-up study. | PloS one 20120101 |
Is there benefit in optimising heart failure treatment in over-80 year-old patients? (HF-80 study): study protocol for a randomized controlled trial. | Trials 20120101 |
[The frequency of aspirin resistance by a modified thrombelastography method and its relationship with clinical and laboratory parameters in patients with stable coronary artery disease]. | Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20120101 |
Targeting NADPH oxidases in vascular pharmacology. | Vascular pharmacology 20120101 |
Developing alternatives to systemic toxicity testing approaches. | ALTEX 20120101 |
Engaging HIV-HCV co-infected patients in HCV treatment: the roles played by the prescribing physician and patients' beliefs (ANRS CO13 HEPAVIH cohort, France). | BMC health services research 20120101 |
Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan. | Substance abuse treatment, prevention, and policy 20120101 |
Developments in heart failure 2011. | Congestive heart failure (Greenwich, Conn.) 20120101 |
Amiloride enhances antigen specific CTL by faciliting HBV DNA vaccine entry into cells. | PloS one 20120101 |
Successful long-term treatment of Cushing disease with mifepristone (RU486). | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20120101 |
Quantitative modeling of the physiology of ascites in portal hypertension. | BMC gastroenterology 20120101 |
Mineralocorticoid receptor antagonist for renal protection. | Renal failure 20120101 |
Mineralocorticoid Receptor Blocker Protects against Podocyte-Dependent Glomerulosclerosis. | Nephron extra 20120101 |
Underrepresentation of elderly people in randomised controlled trials. The example of trials of 4 widely prescribed drugs. | PloS one 20120101 |
Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat. | PloS one 20120101 |
Hepatoprotective effect of the selective mineralocorticoid receptor antagonist, eplerenone against carbon tetrachloride-induced liver injury in rats. | Annals of hepatology 20120101 |
Influence of Angiotensin II Subtype 2 Receptor (AT(2)R) Antagonist, PD123319, on Cardiovascular Remodelling of Aged Spontaneously Hypertensive Rats during Chronic Angiotensin II Subtype 1 Receptor (AT(1)R) Blockade. | International journal of hypertension 20120101 |
Observational cohort study of the safety of digoxin use in women with heart failure. | BMJ open 20120101 |
Hypogonadism in the aging male diagnosis, potential benefits, and risks of testosterone replacement therapy. | International journal of endocrinology 20120101 |
Interactions between noradrenaline and corticosteroids in the brain: from electrical activity to cognitive performance. | Frontiers in cellular neuroscience 20120101 |
Gestural coupling and social cognition: Möbius Syndrome as a case study. | Frontiers in human neuroscience 20120101 |
Reactive Oxygen Species Modulation of Na/K-ATPase Regulates Fibrosis and Renal Proximal Tubular Sodium Handling. | International journal of nephrology 20120101 |
Phenytoin in treatment of amiodarone-induced Torsades de pointes. | Indian journal of pharmacology 20120101 |
Performance scores in general practice: a comparison between the clinical versus medication-based approach to identify target populations. | PloS one 20120101 |
Mixed acid-base disorders, hydroelectrolyte imbalance and lactate production in hypercapnic respiratory failure: the role of noninvasive ventilation. | PloS one 20120101 |
Higher Blood Glucose within the Normal Range Is Associated with More Severe Strokes. | Stroke research and treatment 20120101 |
Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat. | PloS one 20120101 |
Systems toxicology. | ALTEX 20120101 |
A toxicology ontology roadmap. | ALTEX 20120101 |
Toxicology ontology perspectives. | ALTEX 20120101 |
Analysis of the proposed EU regulation concerning biocide products and its opportunities for alternative approaches and a toxicology for the 21st century. | ALTEX 20120101 |
Whole genome analysis and microRNAs regulation in HepG2 cells exposed to cadmium. | ALTEX 20120101 |
Characterization of biologically available wood combustion particles in cell culture medium. | ALTEX 20120101 |
Guidance on determining indispensability and balancing potential benefits of animal experiments with costs to the animals with specific consideration of EU directive 2010/63/EU. | ALTEX 20120101 |
Simultaneous Analysis of Losartan Potassium, Amlodipine Besylate, and Hydrochlorothiazide in Bulk and in Tablets by High-Performance Thin Layer Chromatography with UV-Absorption Densitometry. | Journal of analytical methods in chemistry 20120101 |
Double-blinded, vehicle-controlled proof of concept study to investigate the recurrence of inflammatory and noninflammatory acne lesions using tretinoin gel (microsphere) 0.04% in male patients after oral isotretinoin use. | Dermatology research and practice 20120101 |
Vascular inflammatory cells in hypertension. | Frontiers in physiology 20120101 |
Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos. | PloS one 20120101 |
Life-threatening hyperkalemia--an overlooked acute kidney injury with a serum creatinine rise in the 'normal' range. | BMJ case reports 20120101 |
Spironolactone prevents aldosterone induced increased duration of atrial fibrillation in rat. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101 |
Isoniazid related gynecomastia: Description of a case and systematic review of literature. | Lung India : official organ of Indian Chest Society 20120101 |
Liver cirrhosis prevents atrial fibrillation: A reality or just an illusion? | Journal of cardiovascular disease research 20120101 |
Ethionamide-induced gynecomastia. | Journal of pharmacology & pharmacotherapeutics 20120101 |
The eunuchs of India: An endocrine eye opener. | Indian journal of endocrinology and metabolism 20120101 |
Behavioral aggressiveness in boys with sexual precocity. | Indian journal of endocrinology and metabolism 20120101 |
McCune-Albright syndrome and the extraskeletal manifestations of fibrous dysplasia. | Orphanet journal of rare diseases 20120101 |
Antiarrhythmic potential of aldosterone antagonists in atrial fibrillation. | Cardiology journal 20120101 |
Sesamin: A Naturally Occurring Lignan Inhibits CYP3A4 by Antagonizing the Pregnane X Receptor Activation. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Spironolactone, a possible selective androgen receptor modulator, should be used with caution in patients with metastatic carcinoma of the prostate. | BMJ case reports 20120101 |
Quorum quenching revisited--from signal decays to signalling confusion. | Sensors (Basel, Switzerland) 20120101 |
Aldosterone inhibits the fetal program and increases hypertrophy in the heart of hypertensive mice. | PloS one 20120101 |
The end-organ impairment in liver cirrhosis: appointments for critical care. | Critical care research and practice 20120101 |
Update: Cytokine Dysregulation in Chronic Nonbacterial Osteomyelitis (CNO). | International journal of rheumatology 20120101 |
Angiotensin II, Aldosterone, and Anti-Inflammatory Lymphocytes: Interplay and Therapeutic Opportunities. | International journal of hypertension 20120101 |
A comprehensive review of hypertension in pregnancy. | Journal of pregnancy 20120101 |
Antioxidants in kidney diseases: the impact of bardoxolone methyl. | International journal of nephrology 20120101 |
Intravenous hypertonic saline solution (7.5%) and oral electrolytes to treat of calves with noninfectious diarrhea and metabolic acidosis. | Journal of veterinary internal medicine 20120101 |
Primary aldosteronism in pregnancy. | Acta clinica Belgica 20120101 |
Intrathecal injection of spironolactone attenuates radicular pain by inhibition of spinal microglia activation in a rat model. | PloS one 20120101 |
Resistant hypertension. | Journal of the American Board of Family Medicine : JABFM 20120101 |
First case of dizygotic twins with lamellar ichthyosis in Puerto Rico. | Boletin de la Asociacion Medica de Puerto Rico 20120101 |
Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study. | BMJ (Clinical research ed.) 20120101 |
Increased microparticle production and impaired microvascular endothelial function in aldosterone-salt-treated rats: protective effects of polyphenols. | PloS one 20120101 |
Combined hypotensive treatment with ≥ 3 hypotensive drugs in patients with recurrent atrial fibrillation and arterial hypertension ensures more effective arrhythmia control than using less drugs. | Kardiologia polska 20120101 |
Alternative approaches for medical countermeasures to biological and chemical terrorism and warfare. | ALTEX 20120101 |
Characterization of mouse cell line IMA 2.1 as a potential model system to study astrocyte functions. | ALTEX 20120101 |
Screening of budesonide nanoformulations for treatment of inflammatory bowel disease in an inflamed 3D cell-culture model. | ALTEX 20120101 |
Regulatory acceptance and use of 3R models: a multilevel perspective. | ALTEX 20120101 |
Inconsistencies in data requirements of EU legislation involving tests on animals. | ALTEX 20120101 |
[Management of intraoperative floppy iris syndrome]. | Oftalmologia (Bucharest, Romania : 1990) 20120101 |
Aromatase gene polymorphism does not influence clinical phenotype and response to oral contraceptive pills in polycystic ovary syndrome women. | Gynecologic and obstetric investigation 20120101 |
Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation. | ALTEX 20120101 |
Alternatives discussed at Indian Science Congress. | ALTEX 20120101 |
Stress-induced enhancement of mouse amygdalar synaptic plasticity depends on glucocorticoid and ß-adrenergic activity. | PloS one 20120101 |
[Efficacy of diuretics in the treatment of Morbihan's disease: three cases]. | Annales de dermatologie et de venereologie 20120101 |
Expert consensus: renal denervation for the treatment of arterial hypertension. | Archives of cardiovascular diseases 20120101 |
[Structural and functional changes in myocardium of patients with chronic heart failure treated with spironolactone]. | Klinicheskaia meditsina 20120101 |
Concomitance of Gitelman syndrome and familial Mediterranean fever: a rare case presentation. | Renal failure 20120101 |
Alternative methods in Europe. Editorial. | ALTEX 20120101 |
Reproductive and developmental toxicity testing: from in vivo to in vitro. | ALTEX 20120101 |
Gitelman syndrome manifesting in early childhood and leading to delayed puberty: a case report. | Journal of medical case reports 20120101 |
[Effect of combined treatment with dopamine receptor agonists and antagonists of aldosterone on the performance of daily blood pressure monitoring in patients with hypertension and concomitant obesity]. | Likars'ka sprava 20120101 |
Pneumomediastinum after retching. | BMJ case reports 20120101 |
Spironolactone rescues Dot1a-Af9-mediated repression of endothelin-1 and improves kidney injury in streptozotocin-induced diabetic rats. | PloS one 20120101 |
[Treatment of peritoneal carcinomatosis of gastro-intestinal origin--a retrospective study of 203 cases]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20120101 |
[Some clinical and imaging aspects of lateral sinus thrombophlebitis]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20120101 |
Identification of benzoxazin-3-one derivatives as novel, potent, and selective nonsteroidal mineralocorticoid receptor antagonists. | Journal of medicinal chemistry 20111222 |
Deslongchamps annulations with benzoquinone monoketals. | Organic letters 20111216 |
Mineralocorticoid receptor activation is crucial in the signalling pathway leading to the Anrep effect. | The Journal of physiology 20111215 |
South African hypertension guideline 2011. | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20111214 |
Infection: Spironolactone and increased mortality. | Nature reviews. Gastroenterology & hepatology 20111213 |
Importance of spironolactone in the treatment of acne in adult women. | Journal of the European Academy of Dermatology and Venereology : JEADV 20111201 |
Effect of spironolactone and vitamin E on serum metabolic parameters and insulin resistance in patients with nonalcoholic fatty liver disease. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20111201 |
Effects of aldosterone and related steroids on LPS-induced increased expression of inducible NOS in rat aortic smooth muscle cells. | British journal of pharmacology 20111201 |
Mineralocorticoid antagonism: a novel way to treat sarcopenia and physical impairment in older people? | Clinical endocrinology 20111201 |
Aldosterone increases VEGF-A production in human neutrophils through PI3K, ERK1/2 and p38 pathways. | Biochimica et biophysica acta 20111201 |
A randomized trial on mineralocorticoid receptor blockade in men: effects on stress responses, selective attention, and memory. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20111201 |
Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors. | The Journal of clinical endocrinology and metabolism 20111201 |
A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone. | American journal of physiology. Heart and circulatory physiology 20111201 |
Aldosterone and cortisol predict medium-term left ventricular remodelling following myocardial infarction. | European journal of heart failure 20111201 |
Chronic antagonism of the mineralocorticoid receptor ameliorates hypertension and end organ damage in a rodent model of salt-sensitive hypertension. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20111201 |
Improvement of sodium status to optimize the efficacy of Renin-Angiotensin system blockade. | Current hypertension reports 20111201 |
What is the role of aldosterone excess in resistant hypertension and how should it be investigated and treated? | Current cardiology reports 20111201 |
Beneficial effects of hydrocortisone or spironolactone coating on foreign body response to mesh biomaterial in a mouse model. | Journal of biomedical materials research. Part A 20111201 |
A sensitive and specific HPLC-MS/MS analysis and preliminary pharmacokinetic characterization of isoforskolin in beagle dogs. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111201 |
Matrix metalloproteinase 2 induces epithelial-mesenchymal transition in proximal tubules from the luminal side and progresses fibrosis in mineralocorticoid/salt-induced hypertensive rats. | Journal of hypertension 20111201 |
Pregnancy in women with pulmonary hypertension. | Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20111201 |
Mineralocorticoid receptor antagonists for heart failure. | Expert opinion on pharmacotherapy 20111201 |
Mineralocorticoid receptor antagonists for heart failure. | Expert opinion on pharmacotherapy 20111201 |
Exploiting time in electronic health record correlations. | Journal of the American Medical Informatics Association : JAMIA 20111201 |
A novel mutation of IL1RN in the deficiency of interleukin-1 receptor antagonist syndrome: description of two unrelated cases from Brazil. | Arthritis and rheumatism 20111201 |
Rationale and design of the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial: a randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction. | American heart journal 20111201 |
Hair loss in women: medical and cosmetic approaches to increase scalp hair fullness. | The British journal of dermatology 20111201 |
A randomized study of the beneficial effects of aldosterone antagonism on LV function, structure, and fibrosis markers in metabolic syndrome. | JACC. Cardiovascular imaging 20111201 |
Aldosterone blockade in metabolic syndrome: hitting the target or still missing some links? | JACC. Cardiovascular imaging 20111201 |
Espironolactone improves flow-mediated vasodilatation in subjects with the metabolic syndrome. | Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Chemical pleurodesis for the management of refractory hepatic hydrothorax in patients with decompensated liver cirrhosis. | The Korean journal of hepatology 20111201 |
Fetal and neonatal goiter in cynomolgus monkeys following administration of the antithyroid drug thiamazole at high doses to dams during pregnancy. | Journal of toxicologic pathology 20111201 |
Spironolactone prevents the inducibility of ventricular tachyarrhythmia in rats with aldosteronism. | Journal of cardiovascular pharmacology 20111101 |
The central mechanism underlying hypertension: a review of the roles of sodium ions, epithelial sodium channels, the renin-angiotensin-aldosterone system, oxidative stress and endogenous digitalis in the brain. | Hypertension research : official journal of the Japanese Society of Hypertension 20111101 |
Mineralocorticoid receptors in the medial prefrontal cortex and hippocampus mediate rats' unconditioned fear behaviour. | Hormones and behavior 20111101 |
Design, synthesis, and structure-activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors. | Bioorganic & medicinal chemistry letters 20111101 |
Therapeutic perspectives in hypertension: novel means for renin-angiotensin-aldosterone system modulation and emerging device-based approaches. | European heart journal 20111101 |
Effect of eplerenone on blood pressure and the renin-angiotensin-aldosterone system in oligo-anuric chronic hemodialysis patients - a pilot study. | Clinical nephrology 20111101 |
The predicted impact of heart disease prevention and treatment initiatives on mortality in Lithuania, a middle-income country. | Preventing chronic disease 20111101 |
Aldosterone stimulates the cardiac Na(+)/H(+) exchanger via transactivation of the epidermal growth factor receptor. | Hypertension (Dallas, Tex. : 1979) 20111101 |
Automated framework for digital radiation dose index reporting from CT dose reports. | AJR. American journal of roentgenology 20111101 |
Eplerenone survival benefits in heart failure patients post-myocardial infarction are independent from its diuretic and potassium-sparing effects. Insights from an EPHESUS (Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study) substudy. | Journal of the American College of Cardiology 20111101 |
The month after a novel tale on eplerenone, but with a different ending. | Journal of the American College of Cardiology 20111101 |
Aldosterone, mineralocorticoid receptor activation, and cardiovascular remodeling. | Circulation 20111101 |
Gender differences, polypharmacy, and potential pharmacological interactions in the elderly. | Clinics (Sao Paulo, Brazil) 20111101 |
Update in diuretic therapy: clinical pharmacology. | Seminars in nephrology 20111101 |
Hypokalemic periodic paralysis; two different genes responsible for similar clinical manifestations. | Korean journal of pediatrics 20111101 |
Survival and echocardiographic data in dogs with congestive heart failure caused by mitral valve disease and treated by multiple drugs: a retrospective study of 21 cases. | The Canadian veterinary journal = La revue veterinaire canadienne 20111101 |
Chronic hepatitis in the English springer spaniel: clinical presentation, histological description and outcome. | The Veterinary record 20111015 |
Anabolic steroid associated to physical training induces deleterious cardiac effects. | Medicine and science in sports and exercise 20111001 |
Bartter- and Gitelman-like syndromes: salt-losing tubulopathies with loop or DCT defects. | Pediatric nephrology (Berlin, Germany) 20111001 |
Ventricular repolarization before and after treatment in patients with secondary hypertension due to renal-artery stenosis and primary aldosteronism. | Hypertension research : official journal of the Japanese Society of Hypertension 20111001 |
Retraction. Spirolactone prevents renal dysfunction and fibrosis induced by tacrolimus. | American journal of physiology. Renal physiology 20111001 |
Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney. | American journal of physiology. Renal physiology 20111001 |
Evidence for transcriptional regulation of the urea transporter in the gill of the Gulf toadfish, Opsanus beta. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20111001 |
Eplerenone, an aldosterone antagonist, reduces hospitalization and death in heart failure patients with NYHA class II and an ejection fraction of less than 30%. | Internal and emergency medicine 20111001 |
What is the risk of hyperkalaemia in heart failure? | Expert opinion on pharmacotherapy 20111001 |
Salt overload damages the glycocalyx sodium barrier of vascular endothelium. | Pflugers Archiv : European journal of physiology 20111001 |
Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis. | The Journal of clinical endocrinology and metabolism 20111001 |
Resistant hypertension: concepts and approach to management. | Current hypertension reports 20111001 |
Inhaled iloprost for patients with precapillary pulmonary hypertension and right-side heart failure. | Journal of cardiac failure 20111001 |
Spironolactone revisited. | Journal of clinical hypertension (Greenwich, Conn.) 20111001 |
Pharmacotherapy review of chronic pediatric hypertension. | Clinical therapeutics 20111001 |
Management of patients with chronic kidney disease. | Internal and emergency medicine 20111001 |
Ask the doctor. My 69-year-old husband has had cardiomyopathy and diabetes for several years. Lately his ankles are always swollen. At his last doctor's visit, my husband's cardiologist said his heart has leaky valves and his ejection fraction is 10%. What would be the best plan for him? | Harvard heart letter : from Harvard Medical School 20111001 |
Prognostic value of a new cardiopulmonary exercise testing parameter in chronic heart failure: oxygen uptake efficiency at peak exercise - comparison with oxygen uptake efficiency slope. | Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20111001 |
Mineralocorticoid hypertension. | Indian journal of endocrinology and metabolism 20111001 |
Cushing's surgery: Role of the anesthesiologist. | Indian journal of endocrinology and metabolism 20111001 |
Pediatric endocrine hypertension. | Indian journal of endocrinology and metabolism 20111001 |
Contact dermatitis - epidemiological study. | Maedica 20111001 |
Antidepressant-like effects of mineralocorticoid but not glucocorticoid antagonists in the lateral septum: interactions with the serotonergic system. | Behavioural brain research 20110930 |
Effects of hydrochlorothiazide on cardiac remodeling in a rat model of myocardial infarction-induced congestive heart failure. | European journal of pharmacology 20110930 |
Mild hyperkalemia and low eGFR a tedious recipe for cardiac disaster in the elderly: an unusual reversible cause of syncope and heart block. | Heart international 20110929 |
[Primary hyperaldosteronism]. | Revue medicale suisse 20110914 |
Co-prescription of co-trimoxazole and spironolactone in elderly patients. | BMJ (Clinical research ed.) 20110912 |
Diuretics acting on the distal renal tubule for preterm infants with (or developing) chronic lung disease. | The Cochrane database of systematic reviews 20110907 |
Drug therapy of heart failure: an immunologic view. | American journal of therapeutics 20110901 |
Focal segmental glomerulosclerosis in association with Gitelman syndrome. | International urology and nephrology 20110901 |
Eplerenone suppresses aldosterone/ salt-induced expression of NOX-4. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20110901 |
Efficacy of eplerenone added to renin-angiotensin blockade in elderly hypertensive patients: the Jichi-Eplerenone Treatment (JET) study. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20110901 |
Frequency of laboratory measurement and hyperkalaemia in hospitalised patients using serum potassium concentration increasing drugs. | European journal of clinical pharmacology 20110901 |
Successful bridge to recovery with VAD implantation for anthracycline-induced cardiomyopathy. | Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 20110901 |
NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies. | Basic research in cardiology 20110901 |
Aldosterone-induced fibrosis in the kidney: questions and controversies. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20110901 |
Primary aldosteronism: changes in cystatin C-based kidney filtration, proteinuria, and renal duplex indices with treatment. | Journal of hypertension 20110901 |
Dehydroepiandrosterone-induced phosphorylation and translocation of FoxO1 depend on the mineralocorticoid receptor. | Hypertension (Dallas, Tex. : 1979) 20110901 |
The signer and the sign: cortical correlates of person identity and language processing from point-light displays. | Neuropsychologia 20110901 |
Quality of life in patients with bilateral primary aldosteronism before and during treatment with spironolactone and/or amiloride, including a comparison with our previously published results in those with unilateral disease treated surgically. | The Journal of clinical endocrinology and metabolism 20110901 |
Adipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptors. | Hypertension (Dallas, Tex. : 1979) 20110901 |
Corticosterone microinjected into nucleus pontis oralis increases tonic immobility in rats. | Hormones and behavior 20110901 |
Delineating the receptor mechanisms underlying the rapid vascular contractile effects of aldosterone and estradiol. | Canadian journal of physiology and pharmacology 20110901 |
Aldosterone blockers (mineralocorticoid receptor antagonism) and potassium-sparing diuretics. | Journal of clinical hypertension (Greenwich, Conn.) 20110901 |
Hypertension in people with type 2 diabetes: Update on pharmacologic management. | Canadian family physician Medecin de famille canadien 20110901 |
[Pharmacological sheet: eplerenone (Inspra), orally]. | Journal de pharmacie de Belgique 20110901 |
Contemporary issues in precocious puberty. | Indian journal of endocrinology and metabolism 20110901 |
Effect of aldosterone on the amplification of oncolytic vaccinia virus in human cancer lines. | The Korean journal of hepatology 20110901 |
Chronic, long-lasting, and untreated gout with concomitant dilated cardiomyopathy and exceptionally vast anasarca: case report. | Acta clinica Croatica 20110901 |
Liposome preparation using a hollow fiber membrane contactor--application to spironolactone encapsulation. | International journal of pharmaceutics 20110830 |
The selective mineralocorticoid receptor antagonist eplerenone is protective in mild anti-GBM glomeru-lonephritis. | International journal of clinical and experimental pathology 20110815 |
A personalized medicine target: heart failure in women. | Journal of medicine and life 20110815 |
Aldosterone induction of hepatic stellate cell contraction through activation of RhoA/ROCK-2 signaling pathway. | Regulatory peptides 20110808 |
Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice. | Circulation 20110802 |
Lack of efficacy of low-dose spironolactone as adjunct treatment to conventional congestive heart failure treatment in dogs. | Journal of veterinary pharmacology and therapeutics 20110801 |
Spironolactone inhibits hyperglycemia-induced podocyte injury by attenuating ROS production. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110801 |
Role of cellular mechanics in the function and life span of vascular endothelium. | Pflugers Archiv : European journal of physiology 20110801 |
Use of conventional surfactant media as surrogates for FaSSIF in simulating in vivo dissolution of BCS class II drugs. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110801 |
Aldosterone regulates vascular gene transcription via oxidative stress-dependent and -independent pathways. | Arteriosclerosis, thrombosis, and vascular biology 20110801 |
Ivabradine, a novel heart rate slower: is it a sword of double blades in patients with idiopathic dilated cardiomyopathy? | Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20110801 |
Appropriateness and complications of the use of spironolactone in patients treated in a heart failure clinic. | European journal of internal medicine 20110801 |
Spironolactone is more effective than eplerenone at lowering blood pressure in patients with primary aldosteronism. | Journal of clinical hypertension (Greenwich, Conn.) 20110801 |
Results of the Randomized Aldosterone Antagonism in Heart Failure with Preserved Ejection Fraction trial (RAAM-PEF). | Journal of cardiac failure 20110801 |
A new baseline scoring system may help to predict response to cardiac resynchronization therapy. | Archives of medical science : AMS 20110801 |
Right atrial appendage pacing in cardiac resynchronization therapy - haemodynamic consequences of interatrial conduction delay. | Archives of medical science : AMS 20110801 |
Transcriptome analysis of aldosterone-regulated genes in human vascular endothelial cell lines stably expressing mineralocorticoid receptor. | Molecular and cellular endocrinology 20110720 |
Kidney impairment in primary aldosteronism. | Clinica chimica acta; international journal of clinical chemistry 20110715 |
Prognostic value of plasma renin activity in heart failure. | The American journal of cardiology 20110715 |
Older blood pressure medications-do they still have a place? | The American journal of cardiology 20110715 |
Brief neck restraint stress enhances long-term potentiation and suppresses long-term depression in the dentate gyrus of the mouse. | Brain research bulletin 20110715 |
Glucocorticoid and mineralocorticoid receptors regulate paracellular permeability in a primary cultured gill epithelium. | The Journal of experimental biology 20110715 |
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. | Journal of medicinal chemistry 20110714 |
Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells. | Toxicology 20110711 |
The association of serum potassium level with left ventricular mass in patients with primary aldosteronism. | European journal of clinical investigation 20110701 |
Life-threatening drug-associated hyperkalemia: a retrospective study from laboratory signals. | Pharmacoepidemiology and drug safety 20110701 |
Eplerenone potentiates protective effects of amlodipine against cardiovascular injury in salt-sensitive hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20110701 |
Rapid, nongenomic stimulation of multidrug resistance protein 2 (Mrp2) activity by glucocorticoids in renal proximal tubule. | The Journal of pharmacology and experimental therapeutics 20110701 |
Mineralocorticoid receptor expression in human venous smooth muscle cells: a potential role for aldosterone signaling in vein graft arterialization. | American journal of physiology. Heart and circulatory physiology 20110701 |
Microvascular tissue perfusion is impaired in acutely decompensated heart failure and improves following standard treatment. | European journal of heart failure 20110701 |
Successful pregnancy outcome in decompensated chronic liver disease with portal vein thrombosis: case report and review of literature. | European journal of gastroenterology & hepatology 20110701 |
Eplerenone, amlodipine and experimental hypertension: one plus one equals three. | Hypertension research : official journal of the Japanese Society of Hypertension 20110701 |
Effect of spironolactone on patients with atrial fibrillation and structural heart disease. | Clinical cardiology 20110701 |
Characteristics, outcomes and predictors of long-term mortality for patients hospitalized for acute heart failure: a report from the korean heart failure registry. | Korean circulation journal 20110701 |
The respective and interaction effects of spinal GRs and MRs on radicular pain induced by chronic compression of the dorsal root ganglion in the rat. | Brain research 20110617 |
Improvement of the dissolution rate of poorly soluble drugs by solid crystal suspensions. | Molecular pharmaceutics 20110606 |
Hyperaldosteronism is associated with a decrease in number and altered growth factor expression of endothelial progenitor cells in rats. | International journal of cardiology 20110602 |
[Aldosterone and kidney diseases: an emergent paradigm with important clinical implications]. | Nephrologie & therapeutique 20110601 |
Aldosterone antagonists in heart failure. | Journal of cardiovascular pharmacology and therapeutics 20110601 |
Effects of spironolactone on cerebral vessel structure in rats with sustained hypertension. | American journal of hypertension 20110601 |
Endocrine-disrupting effects of spironolactone in female western mosquitofish, Gambusia affinis. | Environmental toxicology and chemistry 20110601 |
Angiotensin II and aldosterone-induced neuronal damage in neurons through an astrocyte-dependent mechanism. | Hypertension research : official journal of the Japanese Society of Hypertension 20110601 |
Mineralocorticoid receptor activation: a major contributor to salt-induced renal injury and hypertension in young rats. | American journal of physiology. Renal physiology 20110601 |
Eplerenone reverses spironolactone-induced painful gynaecomastia in cirrhotics. | Hepatology international 20110601 |
Addition of spironolactone in patients with resistant arterial hypertension (ASPIRANT): a randomized, double-blind, placebo-controlled trial. | Hypertension (Dallas, Tex. : 1979) 20110601 |
[Postpartum cardiomyopathy]. | Deutsche medizinische Wochenschrift (1946) 20110601 |
Tailoring combination oral contraceptives to the individual woman. | Journal of women's health (2002) 20110601 |
Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathy. | The American journal of pathology 20110601 |
Acute-onset bilateral myopia and ciliochoroidal effusion induced by hydrochlorothiazide. | Korean journal of ophthalmology : KJO 20110601 |
Protective effects of eplerenone on podocyte injury in adriamycin nephropathy rats. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20110601 |
Incurred sample reanalysis: different evaluation approaches on data obtained for spironolactone and its active metabolite canrenone. | Bioanalysis 20110601 |
Addition of spironolactone in patients with resistant arterial hypertension (ASPIRANT)--study protocol. | Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20110601 |
Direct Corticosteroid Modulation of GABAergic Neurons in the Anterior Hypothalamic Area of GAD65-eGFP Mice. | The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20110601 |
Controlled antisolvent precipitation of spironolactone nanoparticles by impingement mixing. | International journal of pharmaceutics 20110530 |
Increased medial temporal lobe and striatal grey-matter volume in a rare disorder of androgen excess: a voxel-based morphometry (VBM) study. | The international journal of neuropsychopharmacology 20110501 |
Impairment of endothelial progenitor cell function and vascularization capacity by aldosterone in mice and humans. | European heart journal 20110501 |
Heart failure reversal by ventricular unloading in patients with chronic cardiomyopathy: criteria for weaning from ventricular assist devices. | European heart journal 20110501 |
Time-trends in treatment and cardiovascular events in patients with heart failure: a pharmacosurveillance study. | European journal of heart failure 20110501 |
Role of mineralocorticoid receptor on atrial structural remodeling and inducibility of atrial fibrillation in hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20110501 |
Spironolactone and enalapril differentially up-regulate the expression of VEGF and heme oxygenase-1 in the neonatal rat kidney. | Pediatric research 20110501 |
Unexpected occurrence of adrenal Cushing's syndrome in a patient with systemic lupus erythematosus. | Hypertension research : official journal of the Japanese Society of Hypertension 20110501 |
Conformational analysis of steroid hormone molecules in the lipid environment--a solid-state NMR approach. | Steroids 20110501 |
Two panels of steroid receptor luciferase reporter cell lines for compound profiling. | Combinatorial chemistry & high throughput screening 20110501 |
Effects of spironolactone on cardiac sympathetic nerve activity and left ventricular remodelling after reperfusion therapy in patients with first ST-segment elevation myocardial infarction. | Heart (British Cardiac Society) 20110501 |
Impact of diabetes mellitus on outcomes in patients with acute myocardial infarction and systolic heart failure. | European journal of heart failure 20110501 |
Mineralocorticoid receptor activation and blockade: an emerging paradigm in chronic kidney disease. | Kidney international 20110501 |
A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism. | Journal of hypertension 20110501 |
Hypoglycemic effect of resveratrol in type 2 diabetic model db/db mice and its actions in cultured L6 myotubes and RIN-5F pancreatic β-cells. | Journal of clinical biochemistry and nutrition 20110501 |
[The EMPHASIS-HF study]. | Giornale italiano di cardiologia (2006) 20110501 |
Treatment of female pattern hair loss with the androgen receptor antagonist flutamide. | The Australasian journal of dermatology 20110501 |
Statin therapy blunts inflammatory activation and improves prognosis and left ventricular performance assessed by Tissue Doppler Imaging in subjects with chronic ischemic heart failure: results from the Daunia Heart Failure Registry. | Clinics (Sao Paulo, Brazil) 20110501 |
Evidence-based diuretic therapy for improving cardiovascular prognosis in systemic hypertension. | The American journal of cardiology 20110415 |
Eplerenone in mild heart failure. | The New England journal of medicine 20110407 |
Eplerenone in mild heart failure. | The New England journal of medicine 20110407 |
Eplerenone in mild heart failure. | The New England journal of medicine 20110407 |
Eplerenone in mild heart failure. | The New England journal of medicine 20110407 |
T-type Ca²+ signalling regulates aldosterone-induced CREB activation and cell death through PP2A activation in neonatal cardiomyocytes. | Cardiovascular research 20110401 |
Timing of defibrillator implant after acute myocardial infarction: what's new? | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110401 |
The kidneys and aldosterone/mineralocorticoid receptor system in salt-sensitive hypertension. | Current hypertension reports 20110401 |
Evaluation of the efficacy and safety of RLY5016, a polymeric potassium binder, in a double-blind, placebo-controlled study in patients with chronic heart failure (the PEARL-HF) trial. | European heart journal 20110401 |
Mineralocorticoid receptor blockade improves diastolic function independent of blood pressure reduction in a transgenic model of RAAS overexpression. | American journal of physiology. Heart and circulatory physiology 20110401 |
Construction of spirolactones with concomitant formation of the fused quaternary centre--application to the synthesis of natural products. | Natural product reports 20110401 |
Effects of treatment with β-blocker and aldosterone antagonist on central and peripheral haemodynamics and oxygenation in cirrhosis. | European journal of gastroenterology & hepatology 20110401 |
[Heart failure]. | Deutsche medizinische Wochenschrift (1946) 20110401 |
The renin-angiotensin-aldosterone system and its blockade in diabetic nephropathy: main focus on the role of aldosterone. | Danish medical bulletin 20110401 |
Upper gastrointestinal bleeding and spironolactone. | Prescrire international 20110401 |
Effects of spironolactone and losartan on diabetic nephropathy in a type 2 diabetic rat model. | Diabetes & metabolism journal 20110401 |
The difficulty of medical management of Cushing disease. | Acta medica Indonesiana 20110401 |
A case of a false-positive anti-myeloperoxidase antibody ELISA in a patient with hypothyroidism. | Chonnam medical journal 20110401 |
11beta-hydroxysteroid dehydrogenase type 1 deficiency prevents memory deficits with aging by switching from glucocorticoid receptor to mineralocorticoid receptor-mediated cognitive control. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110316 |
Diagnosis and therapy of ascites in liver cirrhosis. | World journal of gastroenterology 20110314 |
Characteristics, implementation of evidence-based management and outcome in patients with chronic heart failure: results from the Norwegian heart failure registry. | European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology 20110301 |
Disparate effects of eplerenone, amlodipine and telmisartan on podocyte injury in aldosterone-infused rats. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110301 |
What's new in acne? An analysis of systematic reviews published in 2009-2010. | Clinical and experimental dermatology 20110301 |
Risk factors for bullous pemphigoid in the elderly: a prospective case-control study. | The Journal of investigative dermatology 20110301 |
Spironolactone therapy is associated with reduced ventricular tachycardia rate in patients with cardiomyopathy. | Pacing and clinical electrophysiology : PACE 20110301 |
Mineralocorticoid receptor-mediated DNA damage in kidneys of DOCA-salt hypertensive rats. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110301 |
Influence of spironolactone treatment on endothelial function in non-obese women with polycystic ovary syndrome. | European journal of endocrinology 20110301 |
Effects of eplerenone on nephrotic syndrome in a patient with renovascular hypertension. | Hypertension research : official journal of the Japanese Society of Hypertension 20110301 |
Effects of mineralocorticoid receptor antagonist spironolactone on atrial conduction and remodeling in patients with heart failure. | Journal of cardiology 20110301 |
Genomic and nongenomic stimulatory effect of aldosterone on H+-ATPase in proximal S3 segments. | American journal of physiology. Renal physiology 20110301 |
Aldosterone-receptor antagonists in heart failure: insights after EMPHASIS-HF. | Current heart failure reports 20110301 |
A case of corticotroph carcinoma that caused multiple cranial nerve palsies, destructive petrosal bone invasion, and liver metastasis. | Endocrine pathology 20110301 |
Primary aldosteronism: A Japanese perspective. | Reviews in endocrine & metabolic disorders 20110301 |
Treatment of primary aldosteronism: Where are we now? | Reviews in endocrine & metabolic disorders 20110301 |
Eplerenone for gitelman syndrome in pregnancy. | Nephrology (Carlton, Vic.) 20110301 |
Aldosterone, hypertension, and beyond. | Iranian journal of kidney diseases 20110301 |
Survival rates of early-stage HCV-related liver cirrhosis patients without hepatocellular carcinoma are decreased by alcohol. | Journal of clinical biochemistry and nutrition 20110301 |
Spironolactone does not prevent acute mountain sickness: a prospective, double-blind, randomized, placebo-controlled trial by SPACE Trial Group (spironolactone and acetazolamide trial in the prevention of acute mountain sickness group). | Wilderness & environmental medicine 20110301 |
[Clinical analysis of 6 cases of Bartter syndrome]. | Zhonghua yi xue za zhi 20110301 |
Primary aldosteronism, diagnosis and treatment in Japan. | Reviews in endocrine & metabolic disorders 20110301 |
Effects of spironolactone in spontaneously hypertensive adult rats subjected to high salt intake. | Clinics (Sao Paulo, Brazil) 20110301 |
Total synthesis of cyclo-mumbaistatin analogues through anionic homo-Fries rearrangement. | Chemistry (Weinheim an der Bergstrasse, Germany) 20110225 |
Prenatal overexposure to glucocorticoids programs renal 11β-hydroxysteroid dehydrogenase type 2 expression and salt-sensitive hypertension in the rat. | Journal of hypertension 20110201 |
Therapeutic considerations for severe nodular acne. | American journal of clinical dermatology 20110201 |
Aldosterone-induced kidney injury is mediated by NFκB activation. | Clinical and experimental nephrology 20110201 |
Abbott ARCHITECT clinical chemistry and immunoassay systems: digoxin assays are free of interferences from spironolactone, potassium canrenoate, and their common metabolite canrenone. | Therapeutic drug monitoring 20110201 |
Cryopyrin-associated periodic syndrome: an update on diagnosis and treatment response. | Current allergy and asthma reports 20110201 |
Treatment of heart failure with normal ejection fraction. | Current treatment options in cardiovascular medicine 20110201 |
Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension. | American journal of physiology. Heart and circulatory physiology 20110201 |
C-reactive protein makes human endothelium stiff and tight. | Hypertension (Dallas, Tex. : 1979) 20110201 |
Predictive value of plasma galectin-3 levels in heart failure with reduced and preserved ejection fraction. | Annals of medicine 20110201 |
Aldosterone/Mineralocorticoid receptor stimulation induces cellular senescence in the kidney. | Endocrinology 20110201 |
Validated chromatographic methods for determination of hydrochlorothiazide and spironolactone in pharmaceutical formulation in presence of impurities and degradants. | Journal of chromatographic science 20110201 |
Effects of mineralocorticoid receptor blockade on glucocorticoid-induced renal injury in adrenalectomized rats. | Journal of hypertension 20110201 |
Drug therapy for resistant hypertension: simplifying the approach. | Journal of clinical hypertension (Greenwich, Conn.) 20110201 |
Quadriparesis in an adult--Gitelman syndrome. | JPMA. The Journal of the Pakistan Medical Association 20110201 |
Takotsubo-like severe left ventricular dysfunction after cesarean delivery in a 28-year old woman. | Korean circulation journal 20110201 |
Effect of eplerenone on hypertension-associated renal damage in rats: potential role of peroxisome proliferator activated receptor gamma (PPAR-γ). | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110201 |
[Characteristics, outcome and predictors of one year mortality rate in patients with acute heart failure]. | Vojnosanitetski pregled 20110201 |
Predictors of low cardiac output in decompensated severe heart failure. | Clinics (Sao Paulo, Brazil) 20110201 |
Characterization of the zebrafish (Danio rerio) mineralocorticoid receptor. | Molecular and cellular endocrinology 20110130 |
[Aldosterone exacerbates chronic renal insufficiency]. | Ugeskrift for laeger 20110124 |
L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase. | Cancer 20110115 |
Eplerenone in patients with systolic heart failure and mild symptoms. | The New England journal of medicine 20110106 |
Aldosterone antagonists--last man standing? | The New England journal of medicine 20110106 |
Fermented wheat germ extract (avemar) in the treatment of cardiac remodeling and metabolic symptoms in rats. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Stereoselective construction of a steroid 5α,7α-oxymethylene derivative and its use in the synthesis of eplerenone. | Steroids 20110101 |
High plasma aldosterone concentration is a novel risk factor of cognitive impairment in patients with hypertension. | Hypertension research : official journal of the Japanese Society of Hypertension 20110101 |
Exercise Training for Heart Failure Patients with and without Systolic Dysfunction: An Evidence-Based Analysis of How Patients Benefit. | Cardiology research and practice 20110101 |
Structural, functional, and molecular alterations produced by aldosterone plus salt in rat heart: association with enhanced serum and glucocorticoid-regulated kinase-1 expression. | Journal of cardiovascular pharmacology 20110101 |
Concentration-Dependent Protection by Ethanol Extract of Propolis against γ-Ray-Induced Chromosome Damage in Human Blood Lymphocytes. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Regulation of placental growth by aldosterone and cortisol. | Endocrinology 20110101 |
A case of primary aldosteronism revealed after renal transplantation. | Nature reviews. Nephrology 20110101 |
11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice. | Endocrinology 20110101 |
Case report and mini literature review: anesthetic management for severe peripartum cardiomyopathy complicated with preeclampsia using sufetanil in combined spinal epidural anesthesia. | Yonsei medical journal 20110101 |
Antihypertensive efficacy of spironolactone: what about sex? | Journal of hypertension 20110101 |
Pathophysiological roles of aldosterone and mineralocorticoid receptor in the kidney. | Journal of pharmacological sciences 20110101 |
Standards of medical care in diabetes--2011. | Diabetes care 20110101 |
Efficacy of low dose spironolactone in chronic kidney disease with resistant hypertension. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20110101 |
Hsp72 is an early and sensitive biomarker to detect acute kidney injury. | EMBO molecular medicine 20110101 |
Assessment of drug treatment quality in two Danish health-care centres. | Danish medical bulletin 20110101 |
Spironolactone decreases isoproterenol-induced ventricular fibrosis and matrix metalloproteinase-2 in rats. | Biological & pharmaceutical bulletin 20110101 |
Treatment considerations with aldosterone receptor antagonists. | Journal of clinical hypertension (Greenwich, Conn.) 20110101 |
Evidence-based chronic heart-failure management programmes: reality or myth? | BMJ quality & safety 20110101 |
Health care use and costs of adverse drug events emerging from outpatient treatment in Germany: a modelling approach. | BMC health services research 20110101 |
Evolution of ligand specificity in vertebrate corticosteroid receptors. | BMC evolutionary biology 20110101 |
Benefits from treatment and control of patients with resistant hypertension. | International journal of hypertension 20110101 |
Resistant hypertension workup and approach to treatment. | International journal of hypertension 20110101 |
Progression of Left Ventricular Dysfunction and Remodelling under Optimal Medical Therapy in CHF Patients: Role of Individual Genetic Background. | Cardiology research and practice 20110101 |
The cardiorenal syndrome: a review. | International journal of nephrology 20110101 |
Aortocaval fistula in rat: a unique model of volume-overload congestive heart failure and cardiac hypertrophy. | Journal of biomedicine & biotechnology 20110101 |
Pharmacological and non-pharmacological interventions to influence adipose tissue function. | Cardiovascular diabetology 20110101 |
Evaluating the effects of sevelamer carbonate on cardiovascular structure and function in chronic renal impairment in Birmingham: the CRIB-PHOS randomised controlled trial. | Trials 20110101 |
Heart failure therapy in diabetic patients-comparison with the recent ESC/EASD guideline. | Cardiovascular diabetology 20110101 |
Induction of the Wnt antagonist Dickkopf-1 is involved in stress-induced hippocampal damage. | PloS one 20110101 |
Food for thought ... on validation. A puzzle or a mystery: an approach founded on new science. | ALTEX 20110101 |
Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals. | ALTEX 20110101 |
Current standing and future prospects for the technologies proposed to transform toxicity testing in the 21st century. | ALTEX 20110101 |
Formation of mechanistic categories and local models to facilitate the prediction of toxicity. | ALTEX 20110101 |
Skin sensitisation: the Colipa strategy for developing and evaluating non-animal test methods for risk assessment. | ALTEX 20110101 |
ECVAM prevalidation of three cell transformation assays. | ALTEX 20110101 |
Antihypertensive therapy for patients with obstructive sleep apnea. | Current opinion in nephrology and hypertension 20110101 |
Pathophysiology of resistant hypertension: the role of sympathetic nervous system. | International journal of hypertension 20110101 |
Aldosteronism and resistant hypertension. | International journal of hypertension 20110101 |
Treatment options for polycystic ovary syndrome. | International journal of women's health 20110101 |
Aggressive cardiac involvement in systemic lupus erythematosus: a case report and a comprehensive literature review. | Cardiology research and practice 20110101 |
SM-368229, a novel selective and potent non-steroidal mineralocorticoid receptor antagonist with strong urinary Na+ excretion activity. | Journal of pharmacological sciences 20110101 |
Renal transplantation in a patient with Bartter syndrome and glomerulosclerosis. | Korean journal of pediatrics 20110101 |
Congenital Pelger-Huët anomaly in a Danish/Swedish Farmdog: case report. | Acta veterinaria Scandinavica 20110101 |
[A ten-year follow-up of a 109-year-old woman with myocardial infarction]. | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20110101 |
Acute and critically ill peripartum cardiomyopathy and 'bridge to' therapeutic options: a single center experience with intra-aortic balloon pump, extra corporeal membrane oxygenation and continuous-flow left ventricular assist devices. | Critical care (London, England) 20110101 |
Validation is a key theme in this issue of ALTEX. | ALTEX 20110101 |
Changes in the organization of excitation-contraction coupling structures in failing human heart. | PloS one 20110101 |
Cardiorenal syndrome in acute heart failure syndromes. | International journal of nephrology 20110101 |
Common secondary causes of resistant hypertension and rational for treatment. | International journal of hypertension 20110101 |
Adrenocortical causes of hypertension. | International journal of hypertension 20110101 |
A Regenerative Antioxidant Protocol of Vitamin E and α-Lipoic Acid Ameliorates Cardiovascular and Metabolic Changes in Fructose-Fed Rats. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Prevalence of potential drug interactions in patients in an intensive care unit of a university hospital in Brazil. | Clinics (Sao Paulo, Brazil) 20110101 |
Comparison of the effect of midodrine versus octreotide on hemodynamic status in cirrhotic patients with ascites. | Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110101 |
[Diagnosis of secondary hypertension causing miscarriage during the first trimester of pregnancy]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101 |
Role of the kidneys in resistant hypertension. | International journal of hypertension 20110101 |
Psoriasis carries an increased risk of venous thromboembolism: a Danish nationwide cohort study. | PloS one 20110101 |
Spironolactone diminishes spontaneous ventricular premature beats by reducing HCN4 protein expression in rats with myocardial infarction. | Molecular medicine reports 20110101 |
Cholestasis in patients with Cockayne syndrome and suggested modified criteria for clinical diagnosis. | Orphanet journal of rare diseases 20110101 |
Assessment right atrial thrombus by real-time three dimensional transthoracic echocardiography in patient with dilated cardiomyopathy. | Cardiovascular ultrasound 20110101 |
Gynecomastia - evaluation and current treatment options. | Therapeutics and clinical risk management 20110101 |
BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs. | BMC bioinformatics 20110101 |
Study on the bioequivalence of two formulations of eplerenone in healthy volunteers under fasting conditions: data from a single-center, randomized, single-dose, open-label, 2-way crossover bioequivalence study. | Arzneimittel-Forschung 20110101 |
The prognostic value of non-linear analysis of heart rate variability in patients with congestive heart failure--a pilot study of multiscale entropy. | PloS one 20110101 |
Canola proteins for human consumption: extraction, profile, and functional properties. | Journal of food science 20110101 |
Virus-negative active lymphocytic myocarditis progressing to a fibrotic stage. | Case reports in medicine 20110101 |
Diagnostic value of I-131 NP-59 SPECT/CT scintigraphy in patients with subclinical or atypical features of primary aldosteronism. | Journal of biomedicine & biotechnology 20110101 |
Giant cell myocarditis with incessant ventricular arrhythmias treated successfully with methylprednisolone and rat antithymocyte globulin. | Cardiology research and practice 20110101 |
Acne vulgaris treatment : the current scenario. | Indian journal of dermatology 20110101 |
Pharmacological management of atrial fibrillation: one, none, one hundred thousand. | Cardiology research and practice 20110101 |
Traditional and non-traditional treatments for autism spectrum disorder with seizures: an on-line survey. | BMC pediatrics 20110101 |
[Syndrome CINCA/NOMID]. | Medicina clinica 20110101 |
Use, tolerability and compliance of spironolactone in the treatment of heart failure. | BMC clinical pharmacology 20110101 |
Reducing psychological distress and obesity in Australian farmers by promoting physical activity. | BMC public health 20110101 |
Hyponatremia and congestive heart failure: a marker of increased mortality and a target for therapy. | International journal of nephrology 20110101 |
The causes, consequences, and treatment of left or right heart failure. | Vascular health and risk management 20110101 |
Clinician attitudes toward and use of electronic problem lists: a thematic analysis. | BMC medical informatics and decision making 20110101 |
Interleukin-11-induced capillary leak syndrome in primary hepatic carcinoma patients with thrombocytopenia. | BMC cancer 20110101 |
Food for Thought ... on mapping the human toxome. | ALTEX 20110101 |
Examining the regulatory value of multi-route mammalian acute systemic toxicity studies. | ALTEX 20110101 |
Systematic review of chimpanzee use in monoclonal antibody research and drug development: 1981-2010. | ALTEX 20110101 |
Local lymph node assay: how testing laboratories apply OECD TG 429 for REACH purposes. | ALTEX 20110101 |
Long-term use of aldosterone-receptor antagonists in uncontrolled hypertension: a retrospective analysis. | International journal of hypertension 20110101 |
Cardiac AA amyloidosis in a patient with rheumatoid arthritis and systemic sclerosis: the therapeutic potential of biological reagents. | Scandinavian journal of rheumatology 20110101 |
[Treatment of refractory hepatic encephalopathy associated with insertion of a transjugular intrahepatic portosystemic shunt through new endovascular techniques: a case report]. | Gastroenterologia y hepatologia 20110101 |
Treatment and landmark clinical trials for renoprotection. | Contributions to nephrology 20110101 |
Cardiac arrest caused by torsades de pointes tachycardia after successful atrial flutter radiofrequency catheter ablation. | The open cardiovascular medicine journal 20110101 |
Cardiorenal syndrome: an unsolved clinical problem. | International journal of nephrology 20110101 |
Pharmacological management of cardiorenal syndromes. | International journal of nephrology 20110101 |
Arterial stiffness in chronic kidney disease: the usefulness of a marker of vascular damage. | International journal of nephrology 20110101 |
Cardiac resynchronization therapy guided by late gadolinium-enhancement cardiovascular magnetic resonance. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101 |
Intermediate and long-term followup of percutaneous device closure of fossa ovalis atrial septal defect by the Amplatzer septal occluder in a cohort of 529 patients. | Annals of pediatric cardiology 20110101 |
Pleiotropic effects of glitazones: a double edge sword? | Frontiers in pharmacology 20110101 |
Stroke, high blood pressure and the Renin-Angiotensin-aldosterone system - new developments. | Frontiers in pharmacology 20110101 |
Management strategies for acne vulgaris. | Clinical, cosmetic and investigational dermatology 20110101 |
Effectiveness of anti-inflammatory treatment versus antibiotic therapy and placebo for patients with non-complicated acute bronchitis with purulent sputum. The BAAP Study protocol. | BMC pulmonary medicine 20110101 |
Aromatase inhibitors in men: effects and therapeutic options. | Reproductive biology and endocrinology : RB&E 20110101 |
Diabetic microvascular complications: possible targets for improved macrovascular outcomes. | International journal of nephrology and renovascular disease 20110101 |
Desmoplastic small round cell tumour in a 74 year old man: an uncommon cause of ascites (case report). | Diagnostic pathology 20110101 |
Cardiac resynchronization therapy in the cardiorenal syndrome. | International journal of nephrology 20110101 |
Hirsutism: evaluation and treatment: a reader's dilemma. | Indian journal of dermatology 20110101 |
Author'S reply. | Indian journal of dermatology 20110101 |
[High digoxin serum levels in an elderly patient for the endogenous digoxin-like immunoreactive substances. A case report]. | La Clinica terapeutica 20110101 |
Effect of gender difference in management of heart failure patients in aseer, saudi arabia. | Heart views : the official journal of the Gulf Heart Association 20110101 |
17-α-Hydroxylase deficiency: An unusual case with primary amenorrhea and hypertension. | Indian journal of endocrinology and metabolism 20110101 |
Cabergoline-induced tricuspid regurgitation: Case report and review of literature. | Indian journal of endocrinology and metabolism 20110101 |
Aldosterone and aldosterone receptor antagonists in patients with chronic heart failure. | Vascular health and risk management 20110101 |
In vitro antioxidant of a water-soluble polysaccharide from Dendrobium fimhriatum Hook.var.oculatum Hook. | International journal of molecular sciences 20110101 |
Cardiac hypertrophy and fibrosis in the metabolic syndrome: a role for aldosterone and the mineralocorticoid receptor. | International journal of hypertension 20110101 |
Management of hypertension in high-risk ethnic minority with heart failure. | International journal of hypertension 20110101 |
Left ventricular hypertrophy: major risk factor in patients with hypertension: update and practical clinical applications. | International journal of hypertension 20110101 |
Gitelman's syndrome with persistent hypokalemia - don't forget licorice, alcohol, lemon juice, iced tea and salt depletion: a case report. | Journal of medical case reports 20110101 |
Diabetic nephropathy - Epidemiology in Asia and the current state of treatment. | Indian journal of nephrology 20110101 |
Dual paraneoplastic syndromes in a patient with small cell lung cancer: a case report. | Journal of medical case reports 20110101 |
[Quality of life in glaucoma patients]. | Oftalmologia (Bucharest, Romania : 1990) 20110101 |
Low-dose and very low-dose spironolactone in combination therapy for essential hypertension: evaluation by self-measurement of blood pressure at home. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101 |
Feasibility of externalized peritoneovenous shunt (EPVS) for malignant ascites. | World journal of surgical oncology 20110101 |
Role of the Renin-Angiotensin system and aldosterone on cardiometabolic syndrome. | International journal of hypertension 20110101 |
Rationale and design of the Multidisciplinary Approach to Novel Therapies in Cardiology Oncology Research Trial (MANTICORE 101--Breast): a randomized, placebo-controlled trial to determine if conventional heart failure pharmacotherapy can prevent trastuzumab-mediated left ventricular remodeling among patients with HER2+ early breast cancer using cardiac MRI. | BMC cancer 20110101 |
MCT oil-based diet reverses hypertrophic cardiomyopathy in a patient with very long chain acyl-coA dehydrogenase deficiency. | Indian journal of human genetics 20110101 |
Difficult-to-Treat or Resistant Hypertension: Etiology, Pathophysiology, and Innovative Therapies. | International journal of hypertension 20110101 |
Alopecia: evaluation and treatment. | Clinical, cosmetic and investigational dermatology 20110101 |
Changes in the perceived epidemiology of primary hyperaldosteronism. | International journal of hypertension 20110101 |
Life-threatening hyperkalemia following zoledronic acid infusion for Paget's disease: a case report. | Journal of medical case reports 20110101 |
Serum testosterone levels of HbSS (sickle cell disease) male subjects in Lagos, Nigeria. | BMC research notes 20110101 |
Evaluation of the prevalence of concomitant idiopathic cyclic edema and cellulite. | International journal of medical sciences 20110101 |
The Hirsute woman: challenges in evaluation and management. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101 |
Acupuncture Attenuates Anxiety-Like Behavior by Normalizing Amygdaloid Catecholamines during Ethanol Withdrawal in Rats. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
[Etiologic considerations of postlaryngectomy dysphagia]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101 |
[Low anterior resection of the rectum with total mesorectal excision--immediate results]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101 |
[Rare tumors of the neck--report of two cases]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101 |
[An asymptomatic chronic hypokalaemia]. | Annales de biologie clinique 20110101 |
Cushing syndrome and the anesthesiologist, two case reports. | Indian journal of endocrinology and metabolism 20110101 |
State of the Art Review: Emerging Therapies: The Use of Insulin Sensitizers in the Treatment of Adolescents with Polycystic Ovary Syndrome (PCOS). | International journal of pediatric endocrinology 20110101 |
Necrotizing fasciitis following endoscopic harvesting of the greater saphenous vein for coronary artery bypass graft. | JSLS : Journal of the Society of Laparoendoscopic Surgeons 20110101 |
Acute cholecystits leading to ischemic ECG changes in a patient with no underlying cardiac disease. | JSLS : Journal of the Society of Laparoendoscopic Surgeons 20110101 |
Trimethoprim-sulfamethoxazole induced hyperkalaemia in elderly patients receiving spironolactone: nested case-control study. | BMJ (Clinical research ed.) 20110101 |
Active renin mass concentration to determine aldosterone-to-renin ratio in screening for primary aldosteronism. | International journal of nephrology and renovascular disease 20110101 |
Pharmacovigilance analysis of adverse event reports for aliskiren hemifumarate, a first-in-class direct renin inhibitor. | Therapeutics and clinical risk management 20110101 |
Primary molecular disorders and secondary biological adaptations in bartter syndrome. | International journal of nephrology 20110101 |
[Alternative therapy with ivabradine in patients with functional class III chronic heart failure]. | Kardiologiia 20110101 |
Hypertension and other morbidities with Cushing's syndrome associated with corticosteroids: a review. | Integrated blood pressure control 20110101 |
Short- and long-term physiologic and pharmacologic control of blood pressure in pediatric patients. | Integrated blood pressure control 20110101 |
Expression and function of osteopontin in vascular adventitial fibroblasts and pathological vascular remodeling. | PloS one 20110101 |
Validation of a therapeutic scheme for the treatment of resistant hypertension. | Journal of the American Society of Hypertension : JASH 20110101 |
Can case study approaches speed implementation of the NRC report: 'toxicity testing in the 21st century: a vision and a strategy?'. | ALTEX 20110101 |
An expert consortium review of the EC-commissioned report 'alternative (Non-Animal) methods for cosmetics testing: current status and future prospects - 2010'. | ALTEX 20110101 |
Integrating non-animal test information into an adaptive testing strategy - skin sensitization proof of concept case. | ALTEX 20110101 |
Monocyte activation test (MAT) reliably detects pyrogens in parenteral formulations of human serum albumin. | ALTEX 20110101 |
t⁴ workshop report. Nanotoxicology: 'the end of the beginning' - signs on the roadmap to a strategy for assuring the safe application and use of nanomaterials. | ALTEX 20110101 |
Usefulness Of Ivabradine To Treat 'unexpected' Heart Failure Caused By 'acute' Right Ventricular Pacing. | Indian pacing and electrophysiology journal 20110101 |
Management of cardiopulmonary complications of cirrhosis. | International journal of hepatology 20110101 |
Management of renal failure and ascites in patients with cirrhosis. | International journal of hepatology 20110101 |
Long-term use of low-dose spironolactone in spontaneously hypertensive rats: effects on left ventricular hypertrophy and stiffness. | Pharmacological reports : PR 20110101 |
Eplerenone prevents salt-induced vascular stiffness in Zucker diabetic fatty rats: a preliminary report. | Cardiovascular diabetology 20110101 |
Regulation of excitatory synapses and fearful memories by stress hormones. | Frontiers in behavioral neuroscience 20110101 |
Molecular mechanisms of left ventricular hypertrophy (LVH) in systemic hypertension (SH)-possible therapeutic perspectives. | Journal of the American Society of Hypertension : JASH 20110101 |
The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism. | Journal of translational medicine 20110101 |
Non-steroidal anti-inflammatory drug (NSAID) related inhibition of aldosterone glucuronidation and arterial dysfunction in patients with rheumatoid arthritis: a cross-sectional clinical study. | BMJ open 20110101 |
Viusid, a nutritional supplement, increases survival and reduces disease progression in HCV-related decompensated cirrhosis: a randomised and controlled trial. | BMJ open 20110101 |
Blocking mineralocorticoid receptors prior to retrieval reduces contextual fear memory in mice. | PloS one 20110101 |
Blockade of mineralocorticoid and glucocorticoid receptors reverses stress-induced motor impairments. | Neuroendocrinology 20110101 |
Built-in 5-aminooxazole as an internal activator of the terminal carboxylic acid: an alternative access to macrocyclodepsipeptides. | Chimia 20110101 |
Polycystic ovary syndrome - A metabolic malady, the mother of all lifestyle disorders in women - Can Indian health budget tackle it in future? | Indian journal of endocrinology and metabolism 20110101 |
Mutation screening of the IL-1 receptor antagonist gene in chronic non-bacterial osteomyelitis of childhood and adolescence. | Clinical and experimental rheumatology 20110101 |
[Colorectal cancer--clinical course, epidemiologic and pathologic aspects]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101 |
[Sinonasal headache--reality or mis-diagnosis?]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101 |
[Interactions between oral anticoagulants and other medication in emergency department--a pharmacoepidemiologic approach]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101 |
Gynecomastia during imatinib mesylate treatment for gastrointestinal stromal tumor: a rare adverse event. | BMC gastroenterology 20110101 |
Beyond Extrastriate Body Area (EBA) and Fusiform Body Area (FBA): Context Integration in the Meaning of Actions. | Frontiers in human neuroscience 20110101 |
Pseudo-Bartter syndrome in an infant with congenital chloride diarrhoea. | Srpski arhiv za celokupno lekarstvo 20110101 |
Moderate antiproteinuric effect of add-on aldosterone blockade with eplerenone in non-diabetic chronic kidney disease. A randomized cross-over study. | PloS one 20110101 |
Myocardial recovery in peri-partum cardiomyopathy after continuous flow left ventricular assist device. | Journal of cardiothoracic surgery 20110101 |
Low dose spinal anesthesia for peripartum cardiomyopathy. | Journal of anaesthesiology, clinical pharmacology 20110101 |
No clinical relevance of approved animal experiments after seventeen years. | ALTEX 20110101 |
SATIS ethics ranking of universities in Germany regarding animal use in education. | ALTEX 20110101 |
A replacement-first approach to toxicity testing is necessary to successfully reauthorize TSCA. | ALTEX 20110101 |
How are reproductive toxicity and developmental toxicity addressed in REACH dossiers? | ALTEX 20110101 |
The automated FADU-assay, a potential high-throughput in vitro method for early screening of DNA breakage. | ALTEX 20110101 |
Critical evaluation of the use of dogs in biomedical research and testing in Europe. | ALTEX 20110101 |
A framework program for the teaching of alternative methods (replacement, reduction, refinement) to animal experimentation. | ALTEX 20110101 |
Alternatives to the use of fetal bovine serum: human platelet lysates as a serum substitute in cell culture media. | ALTEX 20110101 |
Assessment of stress in laboratory beagle dogs constrained by a Pavlov sling. | ALTEX 20110101 |
In vitro effects of pirfenidone on cardiac fibroblasts: proliferation, myofibroblast differentiation, migration and cytokine secretion. | PloS one 20110101 |
Role of aldosterone on lung structural remodelling and right ventricular function in congestive heart failure. | BMC cardiovascular disorders 20110101 |
Alterations in the interleukin-1/interleukin-1 receptor antagonist balance modulate cardiac remodeling following myocardial infarction in the mouse. | PloS one 20110101 |
Hypokalaemic paralysis with seemingly pH-neutralized blood gas: liquorice-induced mineralocorticoid effect superimposed on renal tubular acidosis. | Acta clinica Belgica 20110101 |
Are prescribing doctors sensitive to the price that their patients have to pay in the Spanish National Health System? | BMC health services research 20110101 |
Brominated compounds from marine sponges of the genus Aplysina and a compilation of their 13C NMR spectral data. | Marine drugs 20110101 |
Effects of thyroid hormone analogue and a leukotrienes pathway-blocker on renal ischemia/reperfusion injury in mice. | BMC nephrology 20110101 |
Simultaneous identification and quantification of canrenone and 11-α-hydroxy-canrenone by LC-MS and HPLC-UVD. | Journal of biomedicine & biotechnology 20110101 |
Clinical features of cardio-renal syndrome in a cohort of consecutive patients admitted to an internal medicine ward. | The open cardiovascular medicine journal 20110101 |
Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway. | Journal of neuroinflammation 20110101 |
The association between drospirenone and hyperkalemia: a comparative-safety study. | BMC clinical pharmacology 20110101 |
Chylous ascites following laparoscopic living donor nephrectomy. Case report. | Annali italiani di chirurgia 20110101 |
The Basel Declaration: a critical appraisal. | ALTEX 20110101 |
Differential clinical profile of candesartan compared to other angiotensin receptor blockers. | Vascular health and risk management 20110101 |
The preventive effect of N-butanol fraction of Nigella sativa on ethylene glycol-induced kidney calculi in rats. | Pharmacognosy magazine 20110101 |
Inhibition of extracellular signal-regulated kinases ameliorates hypertension-induced renal vascular remodeling in rat models. | International journal of molecular sciences 20110101 |
[Oncological emergencies in the emergency department]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101 |
[Antibiotic therapy in the infected diabetic foot]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101 |
[Pharmacoepidemiologic investigations about the interactions between oral anticoagulants and other drugs in patients with hemostasis disorders]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101 |
Effective Connectivity Modeling for fMRI: Six Issues and Possible Solutions Using Linear Dynamic Systems. | Frontiers in systems neuroscience 20110101 |
Robust Working Memory in an Asynchronously Spiking Neural Network Realized with Neuromorphic VLSI. | Frontiers in neuroscience 20110101 |
Novel Pharmacological Interventions to Maintain Sinus Rhythm after DC Cardioversion. | ISRN cardiology 20110101 |
Diuretic effects of young fruit extracts of bombax ceiba L. In rats. | Indian journal of pharmaceutical sciences 20110101 |
Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency. | Frontiers in immunology 20110101 |
Further studies on the effects of intracrine and extracellular angiotensin II on the regulation of heart cell volume. On the influence of aldosterone and spironolactone. | Regulatory peptides 20101210 |
[Aldosterone blocker in heart failure: life prolonging even in mild symptoms]. | MMW Fortschritte der Medizin 20101202 |
Interference between eplerenone and digoxin in fluorescence polarization immunoassay, microparticle enzyme immunoassay, and affinity column-mediated immunoassay. | Therapeutic drug monitoring 20101201 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Differential effect of spironolactone in chronic constriction injury and vincristine-induced neuropathic pain in rats. | European journal of pharmacology 20101201 |
Acid retention during kidney failure induces endothelin and aldosterone production which lead to progressive GFR decline, a situation ameliorated by alkali diet. | Kidney international 20101201 |
Review article: eplerenone: an underused medication? | Journal of cardiovascular pharmacology and therapeutics 20101201 |
Importance of biomarkers for long-term mortality prediction in acutely dyspneic patients. | Clinical chemistry 20101201 |
The effects of spironolactone on atrial remodeling in patients with preserved left ventricular function after an acute myocardial infarction: a randomized follow-up study. | Coronary artery disease 20101201 |
Overnight rostral fluid shift and obstructive sleep apnea in treatment resistant hypertension: connecting the dots clarifies the picture. | Hypertension (Dallas, Tex. : 1979) 20101201 |
Effect of combined spironolactone-β-blocker ± enalapril treatment on occurrence of symptomatic atrial fibrillation episodes in patients with a history of paroxysmal atrial fibrillation (SPIR-AF study). | The American journal of cardiology 20101201 |
Spironolactone in preventing hypokalemia following traumatic brain injury. | Chinese journal of traumatology = Zhonghua chuang shang za zhi 20101201 |
Spironolactone use at discharge was associated with improved survival in hospitalized patients with systolic heart failure. | American heart journal 20101201 |
Blood pressure control in orthotopic heart transplant and kidney allograft recipients is far from satisfactory. | Transplantation proceedings 20101201 |
Delayed intrathyroidal hematoma causing respiratory distress after a seemingly benign fall: a case report. | International journal of emergency medicine 20101201 |
Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method. | Healthcare informatics research 20101201 |
Effect of spironolactone on left ventricular systolic and diastolic function in patients with early stage chronic kidney disease. | The American journal of cardiology 20101115 |
Improved outcomes with early collaborative care of ambulatory heart failure patients discharged from the emergency department. | Circulation 20101102 |
The effect of spironolactone upon corticosteroid hormone metabolism in patients with early stage chronic kidney disease. | Clinical endocrinology 20101101 |
Management of resistant arterial hypertension: role of spironolactone versus double blockade of the renin-angiotensin-aldosterone system. | Journal of hypertension 20101101 |
The glucocorticoid receptor is required for experimental adrenocorticotrophic hormone-induced hypertension in mice. | Clinical and experimental pharmacology & physiology 20101101 |
Inhibition of the renal renin-angiotensin system and renoprotection by pitavastatin in type1 diabetes. | Clinical and experimental pharmacology & physiology 20101101 |
Increased renal alpha-epithelial sodium channel (ENAC) protein and increased ENAC activity in normal pregnancy. | American journal of physiology. Regulatory, integrative and comparative physiology 20101101 |
Both mineralocorticoid and glucocorticoid receptors regulate emotional memory in mice. | Neurobiology of learning and memory 20101101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
The positive predictive value of a hyperkalemia diagnosis in automated health care data. | Pharmacoepidemiology and drug safety 20101101 |
Spironolactone interference in the immunoassay of androstenedione. | Annals of clinical biochemistry 20101101 |
Treatment of resistant hypertension. | Journal of hypertension 20101101 |
Spironolactone management of resistant hypertension. | The Annals of pharmacotherapy 20101101 |
Pseudoaldosteronism with increased serum cortisol associated with pneumonia, hypouricemia, hypocalcemia, and hypophosphatemia. | Clinical nephrology 20101101 |
Effect of spironolactone on left ventricular ejection fraction and volumes in patients with class I or II heart failure. | The American journal of cardiology 20101101 |
Population pharmacokinetic analysis of vancomycin in neonates. A new proposal of initial dosage guideline. | British journal of clinical pharmacology 20101101 |
Effect of eplerenone versus spironolactone on cortisol and hemoglobin A₁(c) levels in patients with chronic heart failure. | American heart journal 20101101 |
Congestive heart failure in Indians: how do we improve diagnosis & management? | The Indian journal of medical research 20101101 |
Clinical, Molecular, and Genetic Characteristics of PAPA Syndrome: A Review. | Current genomics 20101101 |
[Prothrombotic aldosterone action--a new side of the hormone]. | Postepy higieny i medycyny doswiadczalnej (Online) 20101018 |
Aldosterone and mineralocorticoid receptor antagonists modulate elastin and collagen deposition in human skin. | The Journal of investigative dermatology 20101001 |
Spironolactone and low-dose dexamethasone enhance extinction of contextual fear conditioning. | Progress in neuro-psychopharmacology & biological psychiatry 20101001 |
Mineralocorticoid and glucocorticoid receptors in sciatic nerve function and regeneration. | The Journal of steroid biochemistry and molecular biology 20101001 |
A patient with Graves' disease who survived despite developing thyroid storm and lactic acidosis. | Upsala journal of medical sciences 20101001 |
Refractory ascites: can it be defined only by the response to furosemide and spironolactone? | Liver international : official journal of the International Association for the Study of the Liver 20101001 |
Effects of selective mineralocorticoid receptor antagonism on atrial ion currents and early ionic tachycardia-induced electrical remodelling in rabbits. | Naunyn-Schmiedeberg's archives of pharmacology 20101001 |
Temporal trends in adherence to cardiovascular medications in elderly patients after hospitalization for heart failure. | Clinical pharmacology and therapeutics 20101001 |
[Bullous pemphigoid]. | Presse medicale (Paris, France : 1983) 20101001 |
46-year-old man with treatment-resistant hypertension. | Mayo Clinic proceedings 20101001 |
Spironolactone use in heart failure patients with end-stage renal disease on hemodialysis: is it safe? | Clinical cardiology 20101001 |
Psychosis associated with usage of herbal slimming products adulterated with sibutramine: a case series. | Clinical toxicology (Philadelphia, Pa.) 20101001 |
Addition of spironolactone to dual blockade of renin angiotensin system dramatically reduces severe proteinuria in renal transplant patients: an uncontrolled pilot study at 6 months. | Transplantation proceedings 20101001 |
An atypical phenotype of hypokalemic periodic paralysis caused by a mutation in the sodium channel gene SCN4A. | Korean journal of pediatrics 20101001 |
Childhood Bartter's syndrome: An Indian case series. | Indian journal of nephrology 20101001 |
Analytical issues in HPLC/MS/MS simultaneous assay of furosemide, spironolactone and canrenone in human plasma samples. | Journal of pharmaceutical and biomedical analysis 20100905 |
[The shadow of 'RALES' is long]. | Atencion primaria 20100901 |
Effect of eplerenone on endothelial progenitor cells and oxidative stress in ischemic hindlimb. | American journal of hypertension 20100901 |
Mineralocorticoid receptor activation contributes to salt-induced hypertension and renal injury in prepubertal Dahl salt-sensitive rats. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100901 |
Spironolactone ameliorates podocytic adhesive capacity via restoring integrin alpha 3 expression in streptozotocin-induced diabetic rats. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20100901 |
Reduction of endothelial tight junction proteins is related to cerebral aneurysm formation in rats. | Journal of hypertension 20100901 |
Aldosterone blockade in chronic kidney disease: can it improve outcome? | Current opinion in nephrology and hypertension 20100901 |
Aldosterone, hypertension and heart failure: insights from clinical trials. | Hypertension research : official journal of the Japanese Society of Hypertension 20100901 |
Hyperaldosteronism and left ventricular hypertrophy. | Hypertension (Dallas, Tex. : 1979) 20100901 |
Aldosterone and angiogenesis. | American journal of hypertension 20100901 |
Aldosterone modulates cell proliferation and apoptosis in the neonatal rat heart. | Journal of Korean medical science 20100901 |
Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism. | Journal of Korean medical science 20100901 |
Childhood idiopathic steroid resistant nephrotic syndrome in Southwestern Nigeria. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100901 |
Clinical Inquiries: Which drugs should post-MI patients routinely receive? | The Journal of family practice 20100901 |
The effect of aldosterone antagonists for ventricular arrhythmia: a meta-analysis. | Clinical cardiology 20100901 |
Syncope caused by hyperkalemia during use of a combined therapy with the angiotensin-converting enzyme inhibitor and spironolactone. | Kardiologia polska 20100901 |
Aldosterone antagonist decreases blood pressure and improves metabolic parameters in obese patients with the metabolic syndrome. | Journal of clinical hypertension (Greenwich, Conn.) 20100901 |
Epidemiological, clinical e therapeutic profile of heart failure in a tertiary hospital. | Arquivos brasileiros de cardiologia 20100901 |
Evaluation of left ventricular dyssynchrony using combined pulsed wave and tissue Doppler imaging. | Archives of medical science : AMS 20100830 |
Discovery of (3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic acid (PF-3882845), an orally efficacious mineralocorticoid receptor (MR) antagonist for hypertension and nephropathy. | Journal of medicinal chemistry 20100826 |
Spironolactone for hypertension. | The Cochrane database of systematic reviews 20100804 |
Spironolactone reduces severity of obstructive sleep apnoea in patients with resistant hypertension: a preliminary report. | Journal of human hypertension 20100801 |
Oxidative protein labeling in mass-spectrometry-based proteomics. | Analytical and bioanalytical chemistry 20100801 |
Mineralocorticoid receptor overexpression in embryonic stem cell-derived cardiomyocytes increases their beating frequency. | Cardiovascular research 20100801 |
The efficacy and safety of the novel aldosterone antagonist eplerenone in children with hypertension: a randomized, double-blind, dose-response study. | The Journal of pediatrics 20100801 |
Reduction of fibrosis-related arrhythmias by chronic renin-angiotensin-aldosterone system inhibitors in an aged mouse model. | American journal of physiology. Heart and circulatory physiology 20100801 |
Refractory ascites: pathogenesis, definition and therapy of a severe complication in patients with cirrhosis. | Liver international : official journal of the International Association for the Study of the Liver 20100801 |
Central neuronal activation and pressor responses induced by circulating ANG II: role of the brain aldosterone-'ouabain' pathway. | American journal of physiology. Heart and circulatory physiology 20100801 |
A randomized, double-blind, placebo-controlled trial of spironolactone on carotid intima-media thickness in nondiabetic hemodialysis patients. | Clinical journal of the American Society of Nephrology : CJASN 20100801 |
Impact of aldosterone receptor blockade on the deleterious cardiac effects of adrenergic activation in hypertensive rats. | Journal of cardiovascular pharmacology 20100801 |
Drug mechanisms to help in managing resistant hypertension in obesity. | Current hypertension reports 20100801 |
Rationale and design of the 'aldosterone receptor blockade in diastolic heart failure' trial: a double-blind, randomized, placebo-controlled, parallel group study to determine the effects of spironolactone on exercise capacity and diastolic function in patients with symptomatic diastolic heart failure (Aldo-DHF). | European journal of heart failure 20100801 |
Effects of a selective vasopressin V2 receptor antagonist, satavaptan, on ascites recurrence after paracentesis in patients with cirrhosis. | Journal of hepatology 20100801 |
May vaptans contribute to the treatment of refractory ascites? | Journal of hepatology 20100801 |
Mineralocorticoid receptor antagonists and the metabolic syndrome. | Current hypertension reports 20100801 |
Aldosterone inhibition and cardiovascular protection: more important than it once appeared. | Cardiovascular drugs and therapy 20100801 |
Multiple subcutaneous puncture and stoma bag drainage for gross lower limb edema: a case report. | Journal of palliative medicine 20100801 |
Successful treatment of a mycotic aortic pseudoaneurysm in a patient with type 2 diabetes mellitus while treating primary aldosteronism with spironolactone. | Journal of atherosclerosis and thrombosis 20100730 |
Formation of a leuco spirolactone from 4-(2-carboxyphenyl)-7-diethylamino-4'-dimethylamino-1-benzopyrylium: design of a phase-change thermochromic system based on a flavylium dye. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100712 |
Optimal antagonism of the Renin-Angiotensin-aldosterone system: do we need dual or triple therapy? | Drugs 20100709 |
Corticosteroids operate as a switch between memory systems. | Journal of cognitive neuroscience 20100701 |
Effectiveness of initiating treatment with valsartan/hydrochlorothiazide in patients with stage-1 or stage-2 hypertension. | Journal of human hypertension 20100701 |
Cardioprotective effects of mineralocorticoid receptor antagonists at reperfusion. | European heart journal 20100701 |
Spironolactone and canrenone inhibit UGT2B7-catalyzed human liver and kidney microsomal aldosterone 18beta-glucuronidation: a potential drug interaction. | Drug metabolism and disposition: the biological fate of chemicals 20100701 |
Microvascular obstruction remains a portent of adverse remodeling in optimally treated patients with left ventricular systolic dysfunction after acute myocardial infarction. | Circulation. Cardiovascular imaging 20100701 |
Heme arginate therapy enhanced adiponectin and atrial natriuretic peptide, but abated endothelin-1 with attenuation of kidney histopathological lesions in mineralocorticoid-induced hypertension. | The Journal of pharmacology and experimental therapeutics 20100701 |
Effects of central sodium on epithelial sodium channels in rat brain. | American journal of physiology. Regulatory, integrative and comparative physiology 20100701 |
Stress within the postseizure time window inhibits seizure recurrence. | Epilepsy & behavior : E&B 20100701 |
Innovative use of spironolactone as an antiandrogen in the treatment of female pattern hair loss. | Dermatologic clinics 20100701 |
Dyssynchrony by speckle-tracking echocardiography and response to cardiac resynchronization therapy: results of the Speckle Tracking and Resynchronization (STAR) study. | European heart journal 20100701 |
Spironolactone and hydrochlorothiazide decrease vascular stiffness and blood pressure in geriatric hypertension. | Journal of the American Geriatrics Society 20100701 |
Eplerenone suppresses salt-induced vascular endothelial growth factor expression in the kidney. | Kidney & blood pressure research 20100701 |
Blockade of mineralocorticoid receptors improves salt-induced left-ventricular systolic dysfunction through attenuation of enhanced sympathetic drive in mice with pressure overload. | Journal of hypertension 20100701 |
[An elderly man with known heart failure admitted with cardiogenic shock]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20100701 |
Differential actions of eplerenone and spironolactone on the protective effect of testosterone against cardiomyocyte apoptosis in vitro. | Revista espanola de cardiologia 20100701 |
[Improvement of left ventricular function during combined carvedilol, ramipril and spironolactone therapy after myocarditis in patient treated earlier by chemotherapy due to Hodgkin's lymphoma - 3-years follow-up]. | Kardiologia polska 20100701 |
Primary aldosteronism with right-dominant heart failure. | International heart journal 20100701 |
Bilateral renal vein thrombosis and pulmonary embolism secondary to membranous glomerulonephritis treated with percutaneous catheter thrombectomy and localized thrombolytic therapy. | Indian journal of nephrology 20100701 |
Hypertensive brainstem encephalopathy involving deep supratentorial regions: does only blood pressure matter? | Neurology international 20100621 |
Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial. | Lancet (London, England) 20100619 |
Cell and drug delivery therapeutics for controlled renal parenchyma regeneration. | Advanced drug delivery reviews 20100615 |
The L-, N-, and T-type triple calcium channel blocker benidipine acts as an antagonist of mineralocorticoid receptor, a member of nuclear receptor family. | European journal of pharmacology 20100610 |
Abiesatrines A-J: anti-inflammatory and antitumor triterpenoids from Abies georgei Orr. | Organic & biomolecular chemistry 20100607 |
Clinical effects of eplerenone, a selective aldosterone blocker, in Japanese patients with essential hypertension. | Journal of human hypertension 20100601 |
Aldosterone causes DNA strand breaks and chromosomal damage in renal cells, which are prevented by mineralocorticoid receptor antagonists. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100601 |
A patient with Bartter syndrome accompanying severe growth hormone deficiency and focal segmental glomerulosclerosis. | Clinical and experimental nephrology 20100601 |
Acute stress impairs hippocampal mossy fiber-CA3 long-term potentiation by enhancing cAMP-specific phosphodiesterase 4 activity. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100601 |
Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice. | American journal of physiology. Heart and circulatory physiology 20100601 |
Rationale and design of the Eplerenone combination Versus conventional Agents to Lower blood pressure on Urinary Antialbuminuric Treatment Effect (EVALUATE) trial: a double-blinded randomized placebo-controlled trial to evaluate the antialbuminuric effects of an aldosterone blocker in hypertensive patients with albuminuria. | Hypertension research : official journal of the Japanese Society of Hypertension 20100601 |
Rationale and design of the Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure (EMPHASIS-HF). | European journal of heart failure 20100601 |
Contribution of mineralocorticoid and glucocorticoid receptors to the chronotropic and hypertrophic actions of aldosterone in neonatal rat ventricular myocytes. | Endocrinology 20100601 |
The effects of the selective mineralocorticoid receptor antagonist eplerenone on hepatic fibrosis induced by bile duct ligation in rat. | International journal of molecular medicine 20100601 |
Current treatment of chronic heart failure in primary care; still room for improvement. | Journal of evaluation in clinical practice 20100601 |
Aldosterone: role in edematous disorders, hypertension, chronic renal failure, and metabolic syndrome. | Clinical journal of the American Society of Nephrology : CJASN 20100601 |
Eplerenone in chronic renal disease: the EVALUATE trial. | Hypertension research : official journal of the Japanese Society of Hypertension 20100601 |
Withdrawal symptoms after gabapentin discontinuation. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100601 |
Liver: diuretic agents for ascites: joining forces from the start? | Nature reviews. Gastroenterology & hepatology 20100601 |
A preclinical pharmacokinetic and pharmacodynamic approach to determine a dose of spironolactone for treatment of congestive heart failure in dog. | Journal of veterinary pharmacology and therapeutics 20100601 |
Norepinephrine remains increased in the six-minute walking test after heart transplantation. | Clinics (Sao Paulo, Brazil) 20100601 |
The efficacy of spironolactone in the treatment of acute respiratory distress syndrome-induced rats. | Singapore medical journal 20100601 |
Gitelman's syndrome: a differential diagnosis of normocalcemic tetany. | The Journal of the Association of Physicians of India 20100601 |
The role of functional foods, nutraceuticals, and food supplements in intestinal health. | Nutrients 20100601 |
Nifedipine, a calcium channel blocker, inhibits inflammatory and fibrogenic gene expressions in advanced glycation end product (AGE)-exposed fibroblasts via mineralocorticoid receptor antagonistic activity. | Biochemical and biophysical research communications 20100528 |
Stereochemical requirements for the mineralocorticoid receptor antagonist activity of dihydropyridines. | Journal of medicinal chemistry 20100527 |
Spironolactone use and renal toxicity: population based longitudinal analysis. | BMJ (Clinical research ed.) 20100518 |
Tissue plasminogen activator antigen predicts medium-term left ventricular end-systolic volume after acute myocardial infarction. | Journal of thrombosis and thrombolysis 20100501 |
Severe respiratory phenotype caused by a de novo Arg528Gly mutation in the CACNA1S gene in a patient with hypokalemic periodic paralysis. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20100501 |
Eplerenone, a selective mineralocorticoid receptor blocker, exerts anxiolytic effects accompanied by changes in stress hormone release. | Journal of psychopharmacology (Oxford, England) 20100501 |
Aldosterone stimulates the proliferation of uterine leiomyoma cells. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20100501 |
Renoprotective effects of mineralocorticoid receptor blockade in heminephrectomized (pro)renin receptor transgenic rats. | Clinical and experimental pharmacology & physiology 20100501 |
Functional characterization of chicken glucocorticoid and mineralocorticoid receptors. | American journal of physiology. Regulatory, integrative and comparative physiology 20100501 |
Sporadic solitary aldosterone- and cortisol-co-secreting adenomas: endocrine, histological and genetic findings in a subtype of primary aldosteronism. | Hypertension research : official journal of the Japanese Society of Hypertension 20100501 |
Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet. | Endocrinology 20100501 |
Monocyte chemoattractant protein-1: a dichotomous role in cardiac remodeling following acute myocardial infarction in man? | Cytokine 20100501 |
Randomized, double-blind, multicenter, placebo-controlled study evaluating the effect of aldosterone antagonism with eplerenone on ventricular remodeling in patients with mild-to-moderate heart failure and left ventricular systolic dysfunction. | Circulation. Heart failure 20100501 |
Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension. | British journal of pharmacology 20100501 |
Rapid reversal of left ventricular hypertrophy and intracardiac volume overload in patients with resistant hypertension and hyperaldosteronism: a prospective clinical study. | Hypertension (Dallas, Tex. : 1979) 20100501 |
Monogenic IL-1 mediated autoinflammatory and immunodeficiency syndromes: finding the right balance in response to danger signals. | Clinical immunology (Orlando, Fla.) 20100501 |
Impact of aldosterone receptor blockade compared with thiazide therapy on sympathetic nervous system function in geriatric hypertension. | Hypertension (Dallas, Tex. : 1979) 20100501 |
Hypertension: spironolactone and resistant hypertension. | Nature reviews. Endocrinology 20100501 |
Hyperkalemia: a threat to RAAS inhibition? | Nature reviews. Nephrology 20100501 |
Renal function in outpatients with chronic heart failure. | Journal of cardiac failure 20100501 |
Efficacy of spironolactone therapy in patients with heart failure with normal ejection fraction. | Heart (British Cardiac Society) 20100501 |
Improved docking, screening and selectivity prediction for small molecule nuclear receptor modulators using conformational ensembles. | Journal of computer-aided molecular design 20100501 |
Spectrophotometric and chemometric determination of hydrochlorothiazide and spironolactone in binary mixture in the presence of their impurities and degradants. | Drug testing and analysis 20100501 |
Everything old is new again: spironolactone and metformin in the treatment of acne. | Journal of drugs in dermatology : JDD 20100501 |
A systematic review and economic evaluation of the clinical effectiveness and cost-effectiveness of aldosterone antagonists for postmyocardial infarction heart failure. | Health technology assessment (Winchester, England) 20100501 |
[Tissue Doppler imaging observation on effect of long-term use of gingko biloba tablet on left ventricular function in patients with chronic heart failure]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20100501 |
Rheumatoid arthritis patients with active disease and no history of cardiac pathology have higher brain natriuretic peptide (BNP) levels than patients with inactive disease or healthy control subjects. | The Ulster medical journal 20100501 |
Gitelman's syndrome presenting as recurrent paralytic ileus due to chronic renal tubular K+ wasting. | The Journal of the Association of Physicians of India 20100501 |
Physiologic tailoring of treatment in resistant hypertension. | Current cardiology reviews 20100501 |
Nodular regenerative hyperplasia of the liver secondary to azathioprine in a patient with inflammatory bowel disease. | The New Zealand medical journal 20100430 |
Naphthospironone a: an unprecedented and highly functionalized polycyclic metabolite from an alkaline mine waste extremophile. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100406 |
Incidence of left ventricular function improvement after primary prevention ICD implantation for non-ischaemic dilated cardiomyopathy: a multicentre experience. | Heart (British Cardiac Society) 20100401 |
Modulation of the mineralocorticoid receptor as add-on treatment in depression: a randomized, double-blind, placebo-controlled proof-of-concept study. | Journal of psychiatric research 20100401 |
Torsades de Pointes induced by a combination of garenoxacin and disopyramide and other cytochrome P450, family 3, subfamily A polypeptide-4-influencing drugs during hypokalemia due to licorice. | Clinical and experimental nephrology 20100401 |
Sympathoinhibitory effect of statins in chronic heart failure. | Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20100401 |
Corticosterone up-regulates expression and function of norepinephrine transporter in SK-N-BE(2)C cells. | Journal of neurochemistry 20100401 |
Effects of spironolactone on atrial structural remodelling in a canine model of atrial fibrillation produced by prolonged atrial pacing. | British journal of pharmacology 20100401 |
Diabetes and drug-associated hyperkalemia: effect of potassium monitoring. | Journal of general internal medicine 20100401 |
Intensive versus conventional therapy to slow the progression of idiopathic glomerular diseases. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20100401 |
Clinical trial: short-term effects of combination of satavaptan, a selective vasopressin V2 receptor antagonist, and diuretics on ascites in patients with cirrhosis without hyponatraemia--a randomized, double-blind, placebo-controlled study. | Alimentary pharmacology & therapeutics 20100401 |
Cardiovascular effects of inhibition of renin-angiotensin-aldosterone system components in hypertensive rats given salt excess. | American journal of physiology. Heart and circulatory physiology 20100401 |
Aldosterone and cortisol acutely stimulate Na+/H+ exchanger activity in the syncytiotrophoblast of the human placenta: effect of fetal sex. | Placenta 20100401 |
Clinical repercussions of analytical interferences due to aldosterone antagonists in digoxin immunoassays: an assessment. | Therapeutic drug monitoring 20100401 |
Mineralocorticoid receptor antagonism prevents hedonic deficits induced by a chronic sodium appetite. | Behavioral neuroscience 20100401 |
Association between renin-angiotensin-aldosterone system blockers and postoperative atrial fibrillation in patients with mild and moderate left ventricular dysfunction. | Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20100401 |
Aldosterone-receptor antagonism as a potential therapeutic option for atrial fibrillation. | British journal of pharmacology 20100401 |
Expanding view of aldosterone action, with an emphasis on rapid action. | Clinical and experimental pharmacology & physiology 20100401 |
A 7-year-old child with Down syndrome and disruptive behaviors. | Journal of developmental and behavioral pediatrics : JDBP 20100401 |
[Effect of spironolactone on the expression of Toll-like receptor 4 in renal tubular epithelia cells exposed to high glucose]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100401 |
Hirsutism: Diagnosis and management. | Gender medicine 20100401 |
Aldosterone receptor antagonists--how cardiovascular actions may explain their beneficial effects in heart failure. | Journal of veterinary pharmacology and therapeutics 20100401 |
Effects of mineralocorticoid and angiotensin II receptor blockers on proteinuria and glomerular podocyte protein expression in a model of minimal change nephrotic syndrome. | Nephrology (Carlton, Vic.) 20100401 |
Application of direct renin inhibition to chronic kidney disease. | Cardiovascular drugs and therapy 20100401 |
Medication adherence, self-care behaviour and knowledge on heart failure in urban South Africa: the Heart of Soweto study. | Cardiovascular journal of Africa 20100401 |
Bilateral adrenal hyperplasia complicated with severe ischemic stroke in a young patient. | International journal of cardiology 20100318 |
The effect of evidence-based medication use on long-term survival in patients hospitalised for heart failure in Western Australia. | The Medical journal of Australia 20100315 |
Oral contraceptives alone and with spironolactone increase sCD40 ligand in PCOS patients. | Archives of gynecology and obstetrics 20100301 |
Extracellular matrix remodeling in atrial fibrosis: mechanisms and implications in atrial fibrillation. | Journal of molecular and cellular cardiology 20100301 |
Mineralocorticoid receptor blockade enhances the antiproteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic rats. | The Journal of pharmacology and experimental therapeutics 20100301 |
Cardio-renal syndromes: report from the consensus conference of the acute dialysis quality initiative. | European heart journal 20100301 |
Blood pressure and diabetic nephropathy. | Diabetes care 20100301 |
Understanding the risk of hyperkalaemia in heart failure: role of aldosterone antagonism. | Postgraduate medical journal 20100301 |
[Effect of aldosterone and its antagonist spironolactone on epithelial-mesenchymal transition of normal rat kidney epithelial cells in high glucose]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100301 |
Aldosterone receptor inhibition alters the viscoelastic biomechanical behavior of the aortic wall. | Experimental biology and medicine (Maywood, N.J.) 20100301 |
Effect of combined angiotensin-converting enzyme and aldosterone inhibition on plasma plasminogen activator inhibitor type 1 levels in chronic hypertensive patients. | Nephrology (Carlton, Vic.) 20100301 |
[Hormonal antiandrogens in acne treatment]. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20100301 |
Steroid assays in paediatric endocrinology. | Journal of clinical research in pediatric endocrinology 20100301 |
Insulin oedema in newly diagnosed type 1 diabetes mellitus. | Journal of clinical research in pediatric endocrinology 20100301 |
Recurrent syncope and hypocalcaemic cardiomyopathy as manifestations of Fahr's syndrome. | Archives of medical science : AMS 20100301 |
Role of Rho kinase and oxidative stress in cardiac fibrosis induced by aldosterone and salt in angiotensin type 1a receptor knockout mice. | Regulatory peptides 20100225 |
Increased expression of mineralocorticoid receptor in human atrial fibrillation and a cellular model of atrial fibrillation. | Journal of the American College of Cardiology 20100223 |
Aldosterone receptor antagonists: effective but often forgotten. | Circulation 20100223 |
N-terminal pro-B-type natriuretic peptide-guided, intensive patient management in addition to multidisciplinary care in chronic heart failure a 3-arm, prospective, randomized pilot study. | Journal of the American College of Cardiology 20100216 |
A continuous and highly effective static mixing process for antisolvent precipitation of nanoparticles of poorly water-soluble drugs. | International journal of pharmaceutics 20100215 |
[Mineralocorticoid receptor antagonists: inhibition of the renin angiotensin system]. | MMW Fortschritte der Medizin 20100211 |
[Effect of spironolactone on L-arginine/iNOS/NO pathway of aortic adventitia in spontaneously hypertensive rats]. | Zhonghua yi xue za zhi 20100209 |
Role of the renin-angiotensin-aldosterone system for control of arterial blood pressure following moderate deficit in total body sodium: balance studies in freely moving dogs. | Clinical and experimental pharmacology & physiology 20100201 |
eNOS knockout mice with advanced diabetic nephropathy have less benefit from renin-angiotensin blockade than from aldosterone receptor antagonists. | The American journal of pathology 20100201 |
Aldosterone abrogates nuclear factor kappaB-mediated tumor necrosis factor alpha production in human neutrophils via the mineralocorticoid receptor. | Hypertension (Dallas, Tex. : 1979) 20100201 |
Anti-androgen treatments. | Annales d'endocrinologie 20100201 |
Agents with antialdosterone properties should be the preferred diuretics for reducing hypertension related atrial fibrillation. | European journal of internal medicine 20100201 |
Baseline plasma NT-proBNP and clinical characteristics: results from the irbesartan in heart failure with preserved ejection fraction trial. | Journal of cardiac failure 20100201 |
Patients' self-assessed functional status in heart failure by New York Heart Association class: a prognostic predictor of hospitalizations, quality of life and death. | Journal of cardiac failure 20100201 |
[PSA and spironolactone]. | Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20100201 |
Direct myocardial implantation of human fetal stem cells in heart failure patients: long-term results. | The heart surgery forum 20100201 |
Combined amiodarone and low-dose carvedilol treatment for severe heart failure in childhood. | Pediatrics international : official journal of the Japan Pediatric Society 20100201 |
Best methods for identification and treatment of PCOS. | Minerva ginecologica 20100201 |
Potential drug-drug interactions and admissions due to drug-drug interactions in patients treated in medical departments. | Wiener klinische Wochenschrift 20100201 |
Eplerenone improves vascular function and reduces platelet activation in diabetic rats. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100201 |
Spironolactone, but not enalapril, potentiates hypoxia-inducible factor-1 alpha and Ets-1 expression in newborn rat kidney. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100201 |
Slow adoption of helpful heart failure drug. Many people who could benefit from spironolactone aren't getting it. | Harvard heart letter : from Harvard Medical School 20100201 |
A suspected case of carbimazole-associated torsades de pointes. | Indian journal of pharmacology 20100201 |
Na, K-ATPase: Ubiquitous Multifunctional Transmembrane Protein and its Relevance to Various Pathophysiological Conditions. | Journal of clinical medicine research 20100201 |
Clinical factors affecting serum potassium concentration in cardio-renal decompensation syndrome. | International journal of cardiology 20100121 |
Serum soluble ST2: a potential novel mediator in left ventricular and infarct remodeling after acute myocardial infarction. | Journal of the American College of Cardiology 20100119 |
Comparison of four different treatment regimens on coagulation parameters, hormonal and metabolic changes in women with polycystic ovary syndrome. | Archives of gynecology and obstetrics 20100101 |
Eplerenone administration has beneficial effect on hepatic paraoxonase 1 activity in diabetic mice. | Atherosclerosis 20100101 |
The effect of spironolactone on sweat and urinary sodium excretion during exercise in humans. | Clinical physiology and functional imaging 20100101 |
High-salt diet increases plasma adiponectin levels independent of blood pressure in hypertensive rats: the role of the renin-angiotensin-aldosterone system. | Journal of hypertension 20100101 |
The epithelial sodium channel (ENaC): Mediator of the aldosterone response in the vascular endothelium? | Steroids 20100101 |
Mifepristone and spironolactone differently alter cocaine intravenous self-administration and cocaine-induced locomotion in C57BL/6J mice. | Addiction biology 20100101 |
Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation. | The Journal of steroid biochemistry and molecular biology 20100101 |
Efficacy of spironolactone therapy in patients with true resistant hypertension. | Hypertension (Dallas, Tex. : 1979) 20100101 |
Attenuation of adverse cardiac effects in prednisolone-treated delta-sarcoglycan-deficient mice by mineralocorticoid-receptor-antagonism. | Neuromuscular disorders : NMD 20100101 |
Beta-blocker therapy and mortality of patients with Chagas cardiomyopathy: a subanalysis of the REMADHE prospective trial. | Circulation. Heart failure 20100101 |
Natriuretic peptides in heart failure: should therapy be guided by BNP levels? | Nature reviews. Cardiology 20100101 |
Aldosterone signaling associates with p300/GATA4 transcriptional pathway during the hypertrophic response of cardiomyocytes. | Circulation journal : official journal of the Japanese Circulation Society 20100101 |
Does the ratio of serum aldosterone to plasma renin activity predict the efficacy of diuretics in hypertension? Results of RENALDO. | Journal of hypertension 20100101 |
Spironolactone for all hypertensive patients? | Journal of hypertension 20100101 |
Role of 11beta-hydroxysteroid dehydrogenase 2 renal activity in potassium homeostasis in rats with chronic renal failure. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100101 |
Association of aldosterone concentration and mineralocorticoid receptor genotype with potassium response to spironolactone in patients with heart failure. | Pharmacotherapy 20100101 |
Standards of medical care in diabetes--2010. | Diabetes care 20100101 |
A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia. | Journal of Korean medical science 20100101 |
Glucocorticoid suppresses steroidogenesis in rat progenitor Leydig cells. | Journal of andrology 20100101 |
Hormonal therapy for acne: why not as first line therapy? facts and controversies. | Clinics in dermatology 20100101 |
Differential DNA methylation correlates with differential expression of angiogenic factors in human heart failure. | PloS one 20100101 |
Doing what comes naturally. | Journal of general internal medicine 20100101 |
Aldosterone in uremia - beyond blood pressure. | Blood purification 20100101 |
Efficacy of spironolactone on survival in dogs with naturally occurring mitral regurgitation caused by myxomatous mitral valve disease. | Journal of veterinary internal medicine 20100101 |
Cost effectiveness of eplerenone in patients with heart failure after acute myocardial infarction who were taking both ACE inhibitors and beta-blockers: subanalysis of the EPHESUS. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101 |
Differential expression of proteoglycans in tissue remodeling and lymphangiogenesis after experimental renal transplantation in rats. | PloS one 20100101 |
Corticosteroids: way upstream. | Molecular brain 20100101 |
Prevalence and characteristics of sleep apnoea in patients with stable heart failure: Results from a heart failure clinic. | BMC pulmonary medicine 20100101 |
Aldosterone and mineralocorticoid receptors in the cardiovascular system. | Progress in cardiovascular diseases 20100101 |
Skeletal muscle insulin resistance in endocrine disease. | Journal of biomedicine & biotechnology 20100101 |
Profound hyponatremia in cirrhosis: a case report. | Cases journal 20100101 |
Impact of rapid antigen detection testing on antibiotic prescription in acute pharyngitis in adults. FARINGOCAT STUDY: a multicentric randomized controlled trial. | BMC family practice 20100101 |
Congenitally corrected transposition of great arteries with severe rhythm disturbances. | Indian pacing and electrophysiology journal 20100101 |
Meta-analysis of combined therapy with angiotensin receptor antagonists versus ACE inhibitors alone in patients with heart failure. | PloS one 20100101 |
Draining Fluids through a Peritoneal Catheter in Newborns after Cardiac Surgery Helps to Control Fluid Balance. | Case reports in medicine 20100101 |
Food for thought...on alternative methods for chemical safety testing. | ALTEX 20100101 |
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing. | ALTEX 20100101 |
First alternative method validated by a retrospective weight-of-evidence approach to replace the Draize eye test for the identification of non-irritant substances for a defined applicability domain. | ALTEX 20100101 |
Serum-free cell culture: the serum-free media interactive online database. | ALTEX 20100101 |
The Center for Alternatives to Animal Testing - Europe (CAAT-EU): a transatlantic bridge for the paradigm shift in toxicology. | ALTEX 20100101 |
[Resistant hypertension: a case report]. | Recenti progressi in medicina 20100101 |
The patchwork of toxicological research for pharmaceutical testing. | ALTEX 20100101 |
Open letter to the German Chancellor Dr. Angela Merkel. Council Directive on the approximation of laws, regulations and administrative provisions of the Member States regarding the protection of animals used for experimental and other scientific purposes. | ALTEX 20100101 |
Severe metabolic alkalosis and recurrent acute on chronic kidney injury in a patient with Crohn's disease. | BMC nephrology 20100101 |
Reversible dilated cardiomyopathy in a patient with Cushing's syndrome. | Congestive heart failure (Greenwich, Conn.) 20100101 |
Recurrent exacerbations of protein-losing enteropathy after initiation of growth hormone therapy in a Fontan patient controlled with spironolactone. | Congenital heart disease 20100101 |
[Chronic kidney disease and the aldosterone/mineralocorticoid receptor system]. | Nihon Jinzo Gakkai shi 20100101 |
Captopril reduces cardiac inflammatory markers in spontaneously hypertensive rats by inactivation of NF-kB. | Journal of inflammation (London, England) 20100101 |
Aldosterone-producing adenoma and other surgically correctable forms of primary aldosteronism. | Orphanet journal of rare diseases 20100101 |
p38 mediates mechanical allodynia in a mouse model of type 2 diabetes. | Molecular pain 20100101 |
[DIRA: life-threatening but treatable inherited inflammatory disease]. | Nederlands tijdschrift voor geneeskunde 20100101 |
Medical Treatment of Hirsutism in Women. | Current medicinal chemistry 20100101 |
Aldosterone augments LOX-1-mediated low-density lipoprotein uptake in human umbilical artery endothelial cells. | Pharmacological reports : PR 20100101 |
Diabetes is an independent predictor of survival 17 years after myocardial infarction: follow-up of the TRACE registry. | Cardiovascular diabetology 20100101 |
Paraoxonase: Its antiatherogenic role in chronic renal failure. | Indian journal of nephrology 20100101 |
Optimal use of beta-blockers in high-risk hypertension: a guide to dosing equivalence. | Vascular health and risk management 20100101 |
In-hospital percentage BNP reduction is highly predictive for adverse events in patients admitted for acute heart failure: the Italian RED Study. | Critical care (London, England) 20100101 |
Evaluation of three chitin metal silicate co-precipitates as a potential multifunctional single excipient in tablet formulations. | Marine drugs 20100101 |
Combination therapy in hypertension: An update. | Diabetology & metabolic syndrome 20100101 |
Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. | BMC medicine 20100101 |
Topiramate-induced angle closure with acute myopia, macular striae. | Oman journal of ophthalmology 20100101 |
Management of the adult with congenital adrenal hyperplasia. | International journal of pediatric endocrinology 20100101 |
Rapid UHPLC method for simultaneous determination of vancomycin, terbinafine, spironolactone, furosemide and their metabolites: application to human plasma and urine. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20100101 |
Beta-blocker therapy and hemophagocytic lymphohistiocytosis: a case report. | Cardiology research and practice 20100101 |
[Preoperative and postoperative management of adrenal masses]. | Il Giornale di chirurgia 20100101 |
[Application of cardiac resynchronization therapy and ivabradine in a patient with chronic heart failure]. | Kardiologiia 20100101 |
Renal carcinoma infiltrating inferior vena cava and combined valvular heart disease--one-stage uro-cardiological procedure: a case report. | World journal of surgical oncology 20100101 |
Food for thought ... on alternative methods for nanoparticle safety testing. | ALTEX 20100101 |
Investigation of bone allografts representing different steps of the bone bank procedure using the CAM-model. | ALTEX 20100101 |
Pancreatic beta cell lines and their applications in diabetes mellitus research. | ALTEX 20100101 |
The botulinum neurotoxin LD50 test - problems and solutions. | ALTEX 20100101 |
Effect of ramipril alone compared to ramipril with eplerenone on diabetic nephropathy in streptozocin-induced diabetic rats. | Pharmacology 20100101 |
[Heterotopic accessory pancreas in surgical pathology: review of 23 years experience]. | Chirurgia (Bucharest, Romania : 1990) 20100101 |
Current and emerging therapeutic options for the treatment of chronic chagasic cardiomyopathy. | Vascular health and risk management 20100101 |
Routine laboratory results and thirty day and one-year mortality risk following hospitalization with acute decompensated heart failure. | PloS one 20100101 |
The multifaceted role of pirfenidone and its novel targets. | Fibrogenesis & tissue repair 20100101 |
Pleural effusions in children undergoing cardiac surgery. | Annals of pediatric cardiology 20100101 |
Adherence to aldosterone-blocking agents in patients with heart failure. | American journal of therapeutics 20100101 |
Pioglitazone and alogliptin combination therapy in type 2 diabetes: a pathophysiologically sound treatment. | Vascular health and risk management 20100101 |
Aliskiren and valsartan combination therapy for the management of hypertension. | Vascular health and risk management 20100101 |
Role of endothelin receptor A and NADPH oxidase in vascular abnormalities. | Vascular health and risk management 20100101 |
[Determination of brain natriuretic peptide levels and its N-terminal fragment for the evaluation of renal replacement therapies efficiency in patients with decompensated chronic heart failure]. | Terapevticheskii arkhiv 20100101 |
Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model. | Drug metabolism and pharmacokinetics 20100101 |
Advances in systolic heart failure. | F1000 medicine reports 20100101 |
Periodic fever syndrome and autoinflammatory diseases. | F1000 medicine reports 20100101 |
Insulin resistance and glycemic abnormalities are associated with deterioration of left ventricular diastolic function: a cross-sectional study. | Cardiovascular diabetology 20100101 |
A population approach to eplerenone pharmacokinetics and saturable protein binding. | Drug metabolism and pharmacokinetics 20100101 |
Resistant hypertension in an aged woman presenting with clinical features simulating ectopic ACTH syndrome--response to spironolactone--. | Internal medicine (Tokyo, Japan) 20100101 |
Positive predictive value and impact of misdiagnosis of a heart failure diagnosis in administrative registers among patients admitted to a University Hospital cardiac care unit. | Clinical epidemiology 20100101 |
Familial glucocorticoid receptor haploinsufficiency by non-sense mediated mRNA decay, adrenal hyperplasia and apparent mineralocorticoid excess. | PloS one 20100101 |
Re: Efficacy of spironolactone on survival in dogs with naturally occurring mitral regurgitation caused by myxomatous mitral valve disease. | Journal of veterinary internal medicine 20100101 |
Cardiac resynchronization therapy guided by cardiovascular magnetic resonance. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20100101 |
Examining the use of oral contraceptives in the management of acne. | International journal of women's health 20100101 |
Successful blood pressure control with additive administration of eplerenone, an aldosterone receptor blocker, in a patient with bilateral renovascular hypertension treated with angioplasty. | Internal medicine (Tokyo, Japan) 20100101 |
Effect of spironolactone, potassium canrenoate, and their common metabolite canrenone on Dimension Vista Digoxin Assay. | Journal of clinical laboratory analysis 20100101 |
Analysing the large decline in coronary heart disease mortality in the Icelandic population aged 25-74 between the years 1981 and 2006. | PloS one 20100101 |
Food for thought ... why no new in vitro tests will be done for REACH by registrants. | ALTEX 20100101 |
Non-invasive genotyping of transgenic mice: comparison of different commercial kits and required amounts. | ALTEX 20100101 |
Poloxamer 188 supplemented culture medium increases the vitality of Caco-2 cells after subcultivation and freeze/thaw cycles. | ALTEX 20100101 |
Validation of innovative technologies and strategies for regulatory safety assessment methods: challenges and opportunities. | ALTEX 20100101 |
Assuring safety without animal testing: Unilever's ongoing research programme to deliver novel ways to assure consumer safety. | ALTEX 20100101 |
Initiatives to decrease redundancy in animal testing of pesticides. | ALTEX 20100101 |
From the editor. | Journal of the American Society of Hypertension : JASH 20100101 |
The effect of low-dose spironolactone on resistant hypertension. | Journal of the American Society of Hypertension : JASH 20100101 |
Spironolactone for difficult to control hypertension in chronic kidney disease: an analysis of safety and efficacy. | Journal of the American Society of Hypertension : JASH 20100101 |
[Radical neck dissection in advanced thyroid cancer]. | Chirurgia (Bucharest, Romania : 1990) 20100101 |
Effectiveness of long-term (twelve months) nonsurgical weight loss interventions for obese women with polycystic ovary syndrome: a systematic review. | International journal of women's health 20100101 |
Predictors of large volume paracantesis induced circulatory dysfunction in patients with massive hepatic ascites. | Journal of cardiovascular disease research 20100101 |
The critically ill obstetric patient - Recent concepts. | Indian journal of anaesthesia 20100101 |
Uses and benefits of omega-3 ethyl esters in patients with cardiovascular disease. | Journal of multidisciplinary healthcare 20100101 |
Impact of moderate to severe renal impairment on mortality and appropriate shocks in patients with implantable cardioverter defibrillators. | Cardiology research and practice 20100101 |
New insights into the roles of microRNAs in drug addiction and neuroplasticity. | Genome medicine 20100101 |
Individuating faces and common objects produces equal responses in putative face-processing areas in the ventral occipitotemporal cortex. | Frontiers in human neuroscience 20100101 |
Guillain-barré syndrome after thrombolysis with streptokinase. | Cardiology research and practice 20100101 |
Isolated absence of right pulmonary artery. | Annals of pediatric cardiology 20100101 |
Integrated Testing Strategy (ITS) - Opportunities to better use existing data and guide future testing in toxicology. | ALTEX 20100101 |
A mechanistic redefinition of adverse effects - a key step in the toxicity testing paradigm shift. | ALTEX 20100101 |
Evidence-based toxicology - the toolbox of validation for the 21st century? | ALTEX 20100101 |
Courage for simplification and imperfection in the 21st century assessment of 'Endocrine disruption'. | ALTEX 20100101 |
Comparative analysis of the revised Directive 2010/63/EU for the protection of laboratory animals with its predecessor 86/609/EEC - a t4 report. | ALTEX 20100101 |
Dying to learn: the supply and use of companion animals in U.S. colleges and universities. | ALTEX 20100101 |
Food for thought ... considerations and guidelines for basic test method descriptions in toxicology. | ALTEX 20100101 |
Experimental models of duchenne muscular dystrophy: relationship with cardiovascular disease. | The open cardiovascular medicine journal 20100101 |
Experimental models of renal disease and the cardiovascular system. | The open cardiovascular medicine journal 20100101 |
Allopurinol and global left myocardial function in heart failure patients. | Journal of cardiovascular disease research 20100101 |
Experimental models of abdominal aortic aneurysms. | The open cardiovascular medicine journal 20100101 |
Cecal varices presenting as anemia: case report and review of the literature. | Case reports in gastroenterology 20100101 |
A critical look at the national essential medicines list of India 2003. | Journal of pharmacology & pharmacotherapeutics 20100101 |
Juxtaglomerular cell tumor--a rare cause of secondary hypertension. | Bratislavske lekarske listy 20100101 |
Use of spironolactone in dermatology. | Skinmed 20100101 |
Pioglitazone for the treatment of type 2 diabetes in patients inadequately controlled on insulin. | Diabetes, metabolic syndrome and obesity : targets and therapy 20100101 |
Implementation and enforcement of the 3Rs principle in the field of transgenic animals used for scientific purposes. Report and recommendations of the BfR expert workshop, May 18-20, 2009, Berlin, Germany. | ALTEX 20100101 |
[Clinical and paraclinical features in diabetic patients cholecystectomized for gallstones]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20100101 |
[Clinical profile of thyroid nodules in Iaşi, Department of Endocrinology, St. Spiridon Hospital, between 2005-2009]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20100101 |
Analyzing composite outcomes in cardiovascular studies: traditional Cox proportional hazards versus quality-of-life-adjusted survival approaches. | Open medicine : a peer-reviewed, independent, open-access journal 20100101 |
Hypernatremia in a patient treated with sodium polystyrene sulfonate. | International journal of nephrology and renovascular disease 20100101 |
Evidence-based approach for managing hypertension in type 2 diabetes. | Integrated blood pressure control 20100101 |
Critical appraisal of the differential effects of antihypertensive agents on arterial stiffness. | Integrated blood pressure control 20100101 |
Critical analysis of herbs acting on Mutravaha srotas. | Ayu 20100101 |
Prospects of nanotechnology in clinical immunodiagnostics. | Sensors (Basel, Switzerland) 20100101 |
Hawthorn (Crataegus spp.) in the treatment of cardiovascular disease. | Pharmacognosy reviews 20100101 |
Male hypogonadism: Symptoms and treatment. | Journal of advanced pharmaceutical technology & research 20100101 |
Endolymphatic sodium homeostasis by extramacular epithelium of the saccule. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20091216 |
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. | Journal of medicinal chemistry 20091210 |
Aggression in rainbow trout is inhibited by both MR and GR antagonists. | Physiology & behavior 20091207 |
High systemic gentamicin levels and ototoxicity after implantation of gentamicin beads in a 70-year-old man--a case report. | Acta orthopaedica 20091204 |
Role of aldosterone in the progression of chronic kidney disease and potential use of aldosterone blockade in children. | Pediatric nephrology (Berlin, Germany) 20091201 |
Successful effect of triple blockade of renin-angiotensin-aldosterone system on massive proteinuria in a patient with chronic kidney disease. | Clinical and experimental nephrology 20091201 |
Increased renoprotection with ACE inhibitor plus aldosterone antagonist as compared to monotherapies--the effect on podocytes. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201 |
Investigation into the cardiac effects of spironolactone in the experimental model of type 1 diabetes. | Journal of cardiovascular pharmacology 20091201 |
Nitric oxide-mediated dilation of arterioles to intraluminal administration of aldosterone. | Journal of cardiovascular pharmacology 20091201 |
Aldosterone up-regulates 12- and 15-lipoxygenase expression and LDL oxidation in human vascular smooth muscle cells. | Journal of cellular biochemistry 20091201 |
The role of aldosterone in mediating the dependence of angiotensin hypertension on IL-6. | American journal of physiology. Regulatory, integrative and comparative physiology 20091201 |
Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction. | Hypertension (Dallas, Tex. : 1979) 20091201 |
Clinical and serological predictors for the recurrence of atrial fibrillation after electrical cardioversion. | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20091201 |
Spironolactone attenuates experimental uremic cardiomyopathy by antagonizing marinobufagenin. | Hypertension (Dallas, Tex. : 1979) 20091201 |
Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy. | Journal of the American Society of Nephrology : JASN 20091201 |
Novel de novo mutation in the KCNJ2 gene in a patient with Andersen-Tawil syndrome. | Pediatric neurology 20091201 |
Symptomatic hypocalcemia in primary hyperaldosteronism: a case report. | Journal of Korean medical science 20091201 |
Low-dose spironolactone, added to long-term ACE inhibitor therapy, reduces blood pressure and urinary albumin excretion in obese patients with hypertensive target organ damage. | Clinical nephrology 20091201 |
Evidence-based chronic heart failure management programs: reality or myth? | Quality & safety in health care 20091201 |
[Gender differences in pharmacotherapy of chronic heart failure]. | Vnitrni lekarstvi 20091201 |
Relating Population-Code Representations between Man, Monkey, and Computational Models. | Frontiers in neuroscience 20091201 |
Gynecomastia: An ADR due to drug interaction. | Indian journal of pharmacology 20091201 |
Myotonic dystrophy: an anaesthetic dilemma. | Indian journal of anaesthesia 20091201 |
Dialysis unphysiology and sodium balance. | Electrolyte & blood pressure : E & BP 20091201 |
Water and sodium regulation in heart failure. | Electrolyte & blood pressure : E & BP 20091201 |
Dietary salt restriction activates mineralocorticoid receptor signaling in volume-overloaded heart failure. | European journal of pharmacology 20091125 |
Induction of intestinal multidrug resistance-associated protein 2 (Mrp2) by spironolactone in rats. | European journal of pharmacology 20091125 |
Asymptomatic spinal cord involvement in posterior reversible encephalopathy syndrome. | Neurology 20091103 |
At the bottom of the differential diagnosis list: unusual causes of pediatric hypertension. | Pediatric nephrology (Berlin, Germany) 20091101 |
Improved stress response in bipolar affective disorder with adjunctive spironolactone (mineralocorticoid receptor antagonist): case series. | Journal of psychopharmacology (Oxford, England) 20091101 |
Gitelman syndrome during pregnancy: a therapeutic challenge. | Archives of gynecology and obstetrics 20091101 |
Autoregulation of glomerular filtration rate during spironolactone treatment in hypertensive patients with type 1 diabetes: a randomized crossover trial. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091101 |
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism. | American journal of physiology. Heart and circulatory physiology 20091101 |
Use of crospovidone as pelletization aid as alternative to microcrystalline cellulose: effects on pellet properties. | Drug development and industrial pharmacy 20091101 |
Pharmacotherapy: Cardiovascular effects of aldosterone blockade in CKD. | Nature reviews. Cardiology 20091101 |
What is treatment success in cardiac resynchronization therapy? | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20091101 |
The lecanindoles, nonsteroidal progestins from the terrestrial fungus Verticillium lecanii 6144. | Journal of natural products 20091101 |
Timing of eplerenone initiation and outcomes in patients with heart failure after acute myocardial infarction complicated by left ventricular systolic dysfunction: insights from the EPHESUS trial. | European journal of heart failure 20091101 |
Dual blockade of the renin-angiotensin system in diabetic nephropathy. | Diabetes care 20091101 |
Development and validation of an HPLC method for the simultaneous analysis of 23 selected drugs belonging to different therapeutic groups in human urine samples. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20091101 |
Serum cortisol as a useful predictor of cardiac events in patients with chronic heart failure: the impact of oxidative stress. | Circulation. Heart failure 20091101 |
Challenging the dogma of high target doses in the treatment of heart failure: is more always better? | Archives of cardiovascular diseases 20091101 |
The association between left ventricular hypertrophy and biomarkers in patients on continuous ambulatory peritoneal dialysis. | Korean circulation journal 20091101 |
Comparison of effects of low dose of spironolactone and a thiazide diuretic in patients with hypertension treated with an angiotensin-converting enzyme inhibitor or an angiotensin type 1 receptor blocker. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20091101 |
An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis. | Journal of pediatric endocrinology & metabolism : JPEM 20091101 |
Outcome of heart failure with preserved ejection fraction: a multicentre spanish registry. | Current cardiology reviews 20091101 |
Natural history of markers of collagen turnover in patients with early diastolic dysfunction and impact of eplerenone. | Journal of the American College of Cardiology 20091027 |
Heritable forms of hypertension. | Pediatric nephrology (Berlin, Germany) 20091001 |
Treatment of hypertension in children and adolescents. | Pediatric nephrology (Berlin, Germany) 20091001 |
'Population-based outcome studies' of therapy: potentially useful, but not a panacea. | Journal of clinical epidemiology 20091001 |
Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice. | Cardiovascular research 20091001 |
Development and validation of a clinical index to predict survival after cardiac resynchronisation therapy. | Heart (British Cardiac Society) 20091001 |
Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha. | Journal of endocrinological investigation 20091001 |
Mineralocorticoid and glucocorticoid receptors stimulate epithelial sodium channel activity in a mouse model of Cushing syndrome. | Hypertension (Dallas, Tex. : 1979) 20091001 |
Adrenalectomy prevents renal ischemia-reperfusion injury. | American journal of physiology. Renal physiology 20091001 |
Blocking aldosterone in heart failure. | Therapeutic advances in cardiovascular disease 20091001 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
Update in primary aldosteronism. | The Journal of clinical endocrinology and metabolism 20091001 |
A randomized, double-blind, placebo-controlled study to determine the effects of valsartan on exercise time in patients with symptomatic heart failure with preserved ejection fraction. | European journal of heart failure 20091001 |
Short term effects of spironolactone on blood lipid profile: a 3-month study on a cohort of young women with hirsutism. | British journal of clinical pharmacology 20091001 |
Evidence-based management of heart failure in clinical practice: a review of device-based therapy use. | Internal medicine journal 20091001 |
Spironolactone and chlorthalidone in uncontrolled elderly hypertensive patients treated with calcium antagonists and angiotensin II receptor-blocker: effects on endothelial function, inflammation, and oxidative stress. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20091001 |
Spironolactone therapy in heart failure patients with chronic kidney disease. | Clinical cardiology 20091001 |
Rhabdomyolysis due to primary hyperaldosteronism. | Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20091001 |
Effects of cortisol, growth hormone and prolactin on gill claudin expression in Atlantic salmon. | General and comparative endocrinology 20090915 |
[Treatment of hirsutism]. | Praxis 20090909 |
Aldosterone blockade by Spironolactone improves the hypertensive vascular hypertrophy and remodeling in angiotensin II overproducing transgenic mice. | Atherosclerosis 20090901 |
Role of vasopressin and aldosterone in pulmonary arterial hypertension: A pilot study. | Contemporary clinical trials 20090901 |
Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090901 |
Modulation of presynaptic glucocorticoid receptors on glutamate release from rat hippocampal nerve terminals. | Synapse (New York, N.Y.) 20090901 |
Relationships between cardiac resynchronization therapy and N-terminal pro-brain natriuretic peptide in patients with heart failure and markers of cardiac dyssynchrony: an analysis from the Cardiac Resynchronization in Heart Failure (CARE-HF) study. | European heart journal 20090901 |
Multisensory functional magnetic resonance imaging: a future perspective. | Experimental brain research 20090901 |
Mineralocorticoid receptor blockade and calcium channel blockade have different renoprotective effects on glomerular and interstitial injury in rats. | American journal of physiology. Renal physiology 20090901 |
Electrophysiological responses of sympathetic preganglionic neurons to ANG II and aldosterone. | American journal of physiology. Regulatory, integrative and comparative physiology 20090901 |
Uses of proton pump inhibitors and serum potassium levels. | Pharmacoepidemiology and drug safety 20090901 |
Role of mineralocorticoid receptor on experimental cerebral aneurysms in rats. | Hypertension (Dallas, Tex. : 1979) 20090901 |
Losartan reduces the onset of type 2 diabetes in hypertensive Japanese patients with chronic hepatitis C. | Journal of medical virology 20090901 |
The negative inotropic action of canrenone is mediated by L-type calcium current blockade and reduced intracellular calcium transients. | British journal of pharmacology 20090901 |
The effects of eplerenone on length of stay and total days of heart failure hospitalization after myocardial infarction in patients with left ventricular systolic dysfunction. | American heart journal 20090901 |
Treatment with spironolactone for 24 weeks decreases the level of matrix metalloproteinases and improves cardiac function in patients with chronic heart failure of ischemic etiology. | The Canadian journal of cardiology 20090901 |
Aliskiren corrects recurrent hyperreninemia and hyperaldosteronism in autosomal dominant polycystic kidney disease. | Clinical nephrology 20090901 |
Neurohormonal activation in canine degenerative mitral valve disease: implications on pathophysiology and treatment. | The Journal of small animal practice 20090901 |
Cholinesterase inhibitors and hospitalization for bradycardia: a population-based study. | PLoS medicine 20090901 |
Differential regulation of H+-ATPases in MDCK-C11 cells by aldosterone and vasopressin. | Canadian journal of physiology and pharmacology 20090901 |
Complications during enalapril and diuretic therapy for congestive cardiac failure. | Indian journal of pediatrics 20090901 |
Diagnosis of diseases of steroid hormone production, metabolism and action. | Journal of clinical research in pediatric endocrinology 20090901 |
The effects of diuretics on intracellular Ca2+ dynamics of arteriole smooth muscles as revealed by laser confocal microscopy. | Acta histochemica et cytochemica 20090829 |
Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease: a randomized controlled trial. | Journal of the American College of Cardiology 20090804 |
Impact of mediastinal, liver and lung (123)I-metaiodobenzylguanidine ( (123)I-MIBG) washout on calculated (123)I-MIBG myocardial washout. | European journal of nuclear medicine and molecular imaging 20090801 |
Beyond Type D personality: reduced positive affect (anhedonia) predicts impaired health status in chronic heart failure. | Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20090801 |
Aldosterone in clinical nephrology--old hormone, new questions. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090801 |
Growth arrest specific protein 6 participates in DOCA-induced target-organ damage. | Hypertension (Dallas, Tex. : 1979) 20090801 |
Aldosterone induces apoptosis in rat podocytes: role of PI3-K/Akt and p38MAPK signaling pathways. | Nephron. Experimental nephrology 20090801 |
Effect of melatonin, captopril, spironolactone and simvastatin on blood pressure and left ventricular remodelling in spontaneously hypertensive rats. | Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20090801 |
Male gynecomastia. | Mayo Clinic proceedings 20090801 |
Pharmacological options for treatment of hyperandrogenic disorders. | Mini reviews in medicinal chemistry 20090801 |
The effects of trimetazidine on heart rate variability in patients with heart failure. | Arquivos brasileiros de cardiologia 20090801 |
The GH/IGF-1 Axis and Heart Failure. | Current cardiology reviews 20090801 |
Consistency and variability in functional localisers. | NeuroImage 20090715 |
Hypertension of Kcnmb1-/- is linked to deficient K secretion and aldosteronism. | Proceedings of the National Academy of Sciences of the United States of America 20090714 |
Plasma Renin test-guided drug treatment algorithm for correcting patients with treated but uncontrolled hypertension: a randomized controlled trial. | American journal of hypertension 20090701 |
Activation of glucocorticoid receptors increases 5-HT2A receptor levels. | Experimental neurology 20090701 |
Eplerenone does not attenuate diabetes-associated atherosclerosis. | Journal of hypertension 20090701 |
Enhanced distal nephron sodium reabsorption in chronic angiotensin II-infused mice. | Hypertension (Dallas, Tex. : 1979) 20090701 |
[Effects of various diuretics on cardiac function in rats with heart failure]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090701 |
Ascites: diagnosis and management. | The Medical clinics of North America 20090701 |
Thyroid-disrupting chemicals: interpreting upstream biomarkers of adverse outcomes. | Environmental health perspectives 20090701 |
Case of the month. Idiopathic dilated cardiomyopathy. | JAAPA : official journal of the American Academy of Physician Assistants 20090701 |
Establishment of HPLC-ESI-MS method for the determination of eplerenone in human plasma and its pharmacokinetics. | Yao xue xue bao = Acta pharmaceutica Sinica 20090701 |
Association between elevated fibrosis markers and heart failure in the elderly: the cardiovascular health study. | Circulation. Heart failure 20090701 |
Sodium retention in heart failure and cirrhosis: potential role of natriuretic doses of mineralocorticoid antagonist? | Circulation. Heart failure 20090701 |
[Effects of perindopril and spirolactone on plasma aldosterone and left atrial remodeling in a canine model of atrial fibrillation]. | Zhonghua xin xue guan bing za zhi 20090701 |
Preparation and characterization of spironolactone nanoparticles by antisolvent precipitation. | International journal of pharmaceutics 20090622 |
Recognition preference of rhodamine-thiospirolactams for mercury(II) in aqueous solution. | Inorganic chemistry 20090615 |
Angiotensin-converting enzyme is a modifier of hypertensive end organ damage. | The Journal of biological chemistry 20090605 |
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. | The New England journal of medicine 20090604 |
Aldosterone receptor sites on plasma membrane of human vascular endothelium detected by a mechanical nanosensor. | Pflugers Archiv : European journal of physiology 20090601 |
Dexamethasone enhances basal and TNF-alpha-stimulated production of PAI-1 via the glucocorticoid receptor regardless of 11beta-hydroxysteroid dehydrogenase 2 status in human proximal renal tubular cells. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601 |
Aldosterone regulates cellular turnover and mitogen-activated protein kinase family expression in the neonatal rat kidney. | Journal of cellular physiology 20090601 |
Plasma apelin concentration is depressed following acute myocardial infarction in man. | European journal of heart failure 20090601 |
New therapeutic options in patients prone to hypertension: a focus on direct Renin inhibition and aldosterone blockade. | The American journal of the medical sciences 20090601 |
Fenofibrate inhibits aldosterone-induced apoptosis in adult rat ventricular myocytes via stress-activated kinase-dependent mechanisms. | American journal of physiology. Heart and circulatory physiology 20090601 |
Aldosterone blockade attenuates development of an electrophysiological substrate associated with ventricular tachyarrhythmias in heart failure. | Heart rhythm 20090601 |
Usefulness of abnormal heart rate turbulence to predict cardiovascular mortality in high-risk patients with acute myocardial infarction and left ventricular dysfunction (from the EPHESUS study). | The American journal of cardiology 20090601 |
Left ventricular remodeling after acute myocardial infarction: does eplerenone have an effect? | American heart journal 20090601 |
Resistant hypertension. What is the best approach? | Revista espanola de cardiologia 20090601 |
The regulatory role of glucocorticoid and mineralocorticoid receptors in pulsatile urea excretion of the gulf toadfish, Opsanus beta. | The Journal of experimental biology 20090601 |
Integrating statistical predictions and experimental verifications for enhancing protein-chemical interaction predictions in virtual screening. | PLoS computational biology 20090601 |
Established and newly proposed mechanisms of chronic cyclosporine nephropathy. | The Korean journal of internal medicine 20090601 |
Safety of spironolactone use in ambulatory heart failure patients. | Clinical cardiology 20090601 |
Outcome of patients with dilated cardiomyopathy in a contemporary Swiss population. | Acta cardiologica 20090601 |
[The use of aldosterone antagonists in the cardiovascular diseases]. | Kardiologia polska 20090601 |
Treating female pattern hair loss. Noticeable hair loss can be deeply distressing. Here are some medical treatments that may help. | Harvard women's health watch 20090601 |
Are the heart failure guidelines being implemented in primary care? | Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20090601 |
Acquired gitelman syndrome. | Electrolyte & blood pressure : E & BP 20090601 |
[Eplerenone in resistant hypertension with previous spironolactone intolerance]. | Medicina clinica 20090523 |
A history of systemic hypertension and incident heart failure hospitalization in patients with acute myocardial infarction and left ventricular systolic dysfunction. | The American journal of cardiology 20090515 |
Evaluation and management of the patient with difficult-to-control or resistant hypertension. | American family physician 20090515 |
Extracellular cardiac matrix biomarkers in patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure: insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) study. | Circulation 20090512 |
Predictors of development of diabetes in patients with chronic heart failure in the Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM) program. | Diabetes care 20090501 |
Canonical transient receptor potential channels expression is elevated in a porcine model of metabolic syndrome. | Molecular endocrinology (Baltimore, Md.) 20090501 |
Direct action of aldosterone on bicarbonate reabsorption in in vivo cortical proximal tubule. | American journal of physiology. Renal physiology 20090501 |
Aldosterone antagonism or synthase inhibition reduces end-organ damage induced by treatment with angiotensin and high salt. | Kidney international 20090501 |
Regulation of epithelial Na+ channel (ENaC) in the salivary cell line SMG-C6. | Experimental biology and medicine (Maywood, N.J.) 20090501 |
Spironolactone ameliorates transplant vasculopathy in renal chronic transplant dysfunction in rats. | American journal of physiology. Renal physiology 20090501 |
Mineralocorticoid receptor antagonism attenuates glomerular filtration barrier remodeling in the transgenic Ren2 rat. | American journal of physiology. Renal physiology 20090501 |
Effects of eplerenone, a selective mineralocorticoid receptor antagonist, on clinical and experimental salt-sensitive hypertension. | Hypertension research : official journal of the Japanese Society of Hypertension 20090501 |
Mechanisms of impaired potassium handling with dual renin-angiotensin-aldosterone blockade in chronic kidney disease. | Hypertension (Dallas, Tex. : 1979) 20090501 |
[Drugs news]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20090501 |
Coupled calcium and zinc dyshomeostasis and oxidative stress in cardiac myocytes and mitochondria of rats with chronic aldosteronism. | Journal of cardiovascular pharmacology 20090501 |
Diabetic cardiomyopathy. | Clinical science (London, England : 1979) 20090501 |
Prevention of myocardial dysfunction by Eplerenon in experimental tachycardiomyopathy. | Medical science monitor : international medical journal of experimental and clinical research 20090501 |
Successful treatment of female-pattern hair loss with spironolactone in a 9-year-old girl. | The Australasian journal of dermatology 20090501 |
Prevalence and physiological predictors of sleep apnea in patients with heart failure and systolic dysfunction. | Journal of cardiac failure 20090501 |
Treatment of severe edema in children with nephrotic syndrome with diuretics alone--a prospective study. | Clinical journal of the American Society of Nephrology : CJASN 20090501 |
Spironolactone in chronic hemodialysis patients improves cardiac function. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20090501 |
Ameliorative potential of spironolactone in diabetes induced hyperalgesia in mice. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090501 |
Transient tricuspid valve regurgitation following surgical treatment of cor triatriatum dexter in a dog. | The Journal of small animal practice 20090501 |
Aldosterone excess or escape: Treating resistant hypertension. | Journal of clinical hypertension (Greenwich, Conn.) 20090501 |
Changes in the composition of the thoracic aortic wall in spontaneously hypertensive rats treated with losartan or spironolactone. | Clinical and experimental pharmacology & physiology 20090501 |
4-(3-Methyl-anilino)-N-[N-(1-methyl-ethyl)carbamo-yl]pyridinium-3-sulfon-amidate (torasemide) methanol 0.25-solvate 0.25-hydrate. | Acta crystallographica. Section E, Structure reports online 20090501 |
Histopathological study of specimens obtained by left ventricular biopsy during ventriculoplasty for idiopathic dilated cardiomyopathy. | The Tokai journal of experimental and clinical medicine 20090420 |
Chronic cor pulmonale secondary to pulmonary atherosclerosis in an African Grey parrot. | Journal of the American Veterinary Medical Association 20090415 |
Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne. | The Cochrane database of systematic reviews 20090415 |
Drug treatments for polycystic ovary syndrome. | American family physician 20090415 |
Glucocorticoid receptor plays an indispensable role in mineralocorticoid receptor-dependent transcription in GR-deficient BE(2)C and T84 cells in vitro. | Molecular and cellular endocrinology 20090410 |
[Aldosterone antagonists for all patients with heart failure?]. | MMW Fortschritte der Medizin 20090409 |
Stressor and glucocorticoid-dependent induction of the immediate early gene kruppel-like factor 9: implications for neural development and plasticity. | Endocrinology 20090401 |
Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20090401 |
Intrarenal hemodynamics in primary aldosteronism before and after treatment. | The Journal of clinical endocrinology and metabolism 20090401 |
Combined receptor antagonist stimulation of the hypothalamic-pituitary-adrenal axis test identifies impaired negative feedback sensitivity to cortisol in obese men. | The Journal of clinical endocrinology and metabolism 20090401 |
Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2. | Drug metabolism and disposition: the biological fate of chemicals 20090401 |
Health care utilization, barriers to care, and hormone usage among male-to-female transgender persons in New York City. | American journal of public health 20090401 |
Differential effects of chlorthalidone versus spironolactone on muscle sympathetic nerve activity in hypertensive patients. | The Journal of clinical endocrinology and metabolism 20090401 |
Anti-inflammatory effects of eplerenone on viral myocarditis. | European journal of heart failure 20090401 |
A beneficial effect of 3-year spironolactone therapy supplementing atenolol therapy on the remodeling of atria and ventricles in a patient with permanent atrial fibrillation. | Internal and emergency medicine 20090401 |
[Resistant hypertension: evaluation and treatment]. | Presse medicale (Paris, France : 1983) 20090401 |
A comparison of the aldosterone-blocking agents eplerenone and spironolactone. | Clinical cardiology 20090401 |
The clinical pharmacology of eplerenone. | Expert opinion on drug metabolism & toxicology 20090401 |
Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. | Journal of alternative and complementary medicine (New York, N.Y.) 20090401 |
Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension. | Clinics (Sao Paulo, Brazil) 20090401 |
Aldosterone-receptor antagonism in hypertension. | Journal of hypertension 20090401 |
Effect of mineralocorticoid receptor blockade on the renal renin-angiotensin system in Dahl salt-sensitive hypertensive rats. | Journal of hypertension 20090401 |
Sex-specific impact of aldosterone receptor antagonism on ventricular remodeling and gene expression after myocardial infarction. | Clinical and translational science 20090401 |
Anaesthetic management of a patient with hypokalemic periodic paralysis- a case report. | Indian journal of anaesthesia 20090401 |
CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer. | British journal of cancer 20090310 |
Preparation and characterization of spironolactone-loaded gelucire microparticles using spray-drying technique. | Drug development and industrial pharmacy 20090301 |
Hypotension due to the drug interaction of voriconazole with eplerenone and nifedipine. | European journal of clinical pharmacology 20090301 |
Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20090301 |
Risk factors associated with a low glomerular filtration rate in primary aldosteronism. | The Journal of clinical endocrinology and metabolism 20090301 |
Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epithelium. | American journal of physiology. Cell physiology 20090301 |
Conns' syndrome - atypical presentations. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20090301 |
Role of aldosterone receptor antagonist eplerenone in aortic stenosis. | American heart journal 20090301 |
Eplerenone treatment of aortic stenosis. [letter]. | American heart journal 20090301 |
Overview of therapeutic drug monitoring. | The Korean journal of internal medicine 20090301 |
Cost analysis of iron-related complications in a single institute. | The Korean journal of internal medicine 20090301 |
Aliskiren-associated acute renal failure with hyperkalemia. | Clinical nephrology 20090301 |
Rhinophyma treated with cryosurgery. | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20090301 |
Hair loss in women. | Seminars in cutaneous medicine and surgery 20090301 |
Survival of patients with familial dilated cardiomyopathy on optimal heart failure therapy. | Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20090301 |
Iatrogenic hyperkalemia as a serious problem in therapy of cardiovascular diseases in elderly patients. | Polskie Archiwum Medycyny Wewnetrznej 20090301 |
[Renal effect of treatment for heart failure]. | Ugeskrift for laeger 20090223 |
Gap junction remodeling and spironolactone-dependent reverse remodeling in the hypertrophied heart. | Circulation research 20090213 |
Long-term trends in first hospitalization for heart failure and subsequent survival between 1986 and 2003: a population study of 5.1 million people. | Circulation 20090203 |
Steroidal lactones as inhibitors of 17beta-hydroxysteroid dehydrogenase type 5: chemical synthesis, enzyme inhibitory activity, and assessment of estrogenic and androgenic activities. | European journal of medicinal chemistry 20090201 |
Mineralocorticoid and glucocorticoid receptors in the amygdala regulate distinct responses to colorectal distension. | Neuropharmacology 20090201 |
Effects of drospirenone on cardiovascular markers in human aortic endothelial cells. | Climacteric : the journal of the International Menopause Society 20090201 |
The carnitine transporter SLC22A5 is not a general drug transporter, but it efficiently translocates mildronate. | Drug metabolism and disposition: the biological fate of chemicals 20090201 |
A syndrome resembling Bartter's syndrome in sarcoidosis. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090201 |
Renal aspirin: will all patients with chronic kidney disease one day take spironolactone? | Nature clinical practice. Nephrology 20090201 |
Aldosterone blockade and left ventricular dysfunction: a systematic review of randomized clinical trials. | European heart journal 20090201 |
Mineralocorticoid receptor antagonism attenuates vascular apoptosis and injury via rescuing protein kinase B activation. | Hypertension (Dallas, Tex. : 1979) 20090201 |
Usefulness of Type D personality and kidney dysfunction as predictors of interpatient variability in inflammatory activation in chronic heart failure. | The American journal of cardiology 20090201 |
Consensus guidelines for oral dosing of primarily renally cleared medications in older adults. | Journal of the American Geriatrics Society 20090201 |
The effects of trimetazidine on p-wave duration and dispersion in heart failure patients. | Pacing and clinical electrophysiology : PACE 20090201 |
Spironolactone and doxazosin treatment in patients with resistant hypertension. | Revista espanola de cardiologia 20090201 |
Cardiac magnetic resonance imaging and management of dilated cardiomyopathy in a Duchenne muscular dystrophy manifesting carrier. | Journal of neurology 20090201 |
Lupus myocarditis presenting as acute congestive heart failure: a case report. | Journal of Korean medical science 20090201 |
Isolated left ventricular hypertrabeculation/noncompaction in a Turner mosaic with male phenotype. | Acta cardiologica 20090201 |
Molecular imaging for efficacy of pharmacologic intervention in myocardial remodeling. | JACC. Cardiovascular imaging 20090201 |
High potassium. Too much of a good thing. | Mayo Clinic health letter (English ed.) 20090201 |
Patient health status and costs in heart failure: insights from the eplerenone post-acute myocardial infarction heart failure efficacy and survival study (EPHESUS). | Circulation 20090127 |
Identification of a retinal aldosterone system and the protective effects of mineralocorticoid receptor antagonism on retinal vascular pathology. | Circulation research 20090102 |
Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090101 |
Effect of spironolactone on endothelial dysfunction in rheumatoid arthritis. | Scandinavian journal of rheumatology 20090101 |
Contrasting effects of eplerenone and spironolactone on adrenal cell steroidogenesis. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090101 |
Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans. | Diabetes 20090101 |
Spironolactone suppresses inflammation and prevents L-NAME-induced renal injury in rats. | Kidney international 20090101 |
Aldosterone activates NF-kappaB in the collecting duct. | Journal of the American Society of Nephrology : JASN 20090101 |
Cost-effectiveness of treatments reducing coronary heart disease mortality in Ireland, 2000 to 2010. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090101 |
Electrospray ionization tandem mass spectrometric analysis of ent-6,7-seco-kaurane diterpenoids from the Isodon species. | Rapid communications in mass spectrometry : RCM 20090101 |
[Conn's syndrome]. | Der Internist 20090101 |
The Janus effect: two faces of aldosterone. | Kidney international 20090101 |
Standards of medical care in diabetes--2009. | Diabetes care 20090101 |
Death following bilateral complete Achilles tendon rupture in a patient on fluoroquinolone therapy: a case report. | Journal of medical case reports 20090101 |
Eplerenone decreases inflammatory foci in spontaneously hypertensive rat hearts with minimal effects on blood pressure. | Journal of cardiovascular pharmacology 20090101 |
How 40 kilograms of fluid retention can be overlooked: two case reports. | Cases journal 20090101 |
Effects of increased dose of diuretics on symptoms, weight, 6-minute walk distance, and echocardiographic measurements of left ventricular systolic and diastolic function in 51 patients with symptomatic heart failure caused by reduced left ventricular ejection fraction treated with beta blockers and angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. | American journal of therapeutics 20090101 |
Transient loss of consciousness caused by cryptococcal meningitis in an immunocompetent patient: a case report. | Cases journal 20090101 |
Improvement in the management of chronic heart failure since the publication of the updated guidelines of the European Society of Cardiology. The Impact-Reco Programme. | European journal of heart failure 20090101 |
Primary aldosteronism. | Hormone research 20090101 |
Spironolactone alleviates late cardiac remodeling after left ventricular restoration. | The Journal of thoracic and cardiovascular surgery 20090101 |
Gingival hyperplasia associated with the administration of amlodipine to dogs with degenerative valvular disease (2004-2008). | Journal of veterinary internal medicine 20090101 |
Ascites is a negative prognostic indicator in chronic hepatitis in dogs. | Journal of veterinary internal medicine 20090101 |
Regulation of kainate receptor subunit mRNA by stress and corticosteroids in the rat hippocampus. | PloS one 20090101 |
Aldosterone-induced TGF-beta1 expression is regulated by mitogen-activated protein kinases and activator protein-1 in mesangial cells. | Journal of Korean medical science 20090101 |
Impact of spironolactone on endothelial function in patients with single ventricle heart. | Congenital heart disease 20090101 |
Adverse drug reactions in hospital in-patients: a prospective analysis of 3695 patient-episodes. | PloS one 20090101 |
Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response. | PloS one 20090101 |
Prevalence of primary hyperaldosteronism in a systemic arterial hypertension league. | Arquivos brasileiros de cardiologia 20090101 |
Gynecomastia: what the surgeon needs to know. | Eplasty 20090101 |
[Inhibitory effect of carbamazepine on hypotensive action of spironolactone in primary aldosteronism]. | Endokrynologia Polska 20090101 |
[Adherence to pharmaceutical guidance in patients over 85 years of age with chronic heart failure-stage C. Effects on 12-month mortality]. | Revista espanola de geriatria y gerontologia 20090101 |
Compound heterozygous mutation of aquaporin 2 gene in woman patient with congenital nephrogenic diabetes insipidus. | Internal medicine (Tokyo, Japan) 20090101 |
Food for thought... on the economics of animal testing. | ALTEX 20090101 |
Go3R - semantic Internet search engine for alternative methods to animal testing. | ALTEX 20090101 |
SV40-transformed human corneal keratocytes: optimisation of serum-free culture conditions. | ALTEX 20090101 |
20 Years of hypertension research using genetically modified animals: no clinically promising approaches in sight. | ALTEX 20090101 |
Quantification of foot-and-mouth disease virus transmission rates using published data. | ALTEX 20090101 |
Alternatives across Latin America: catalysing change in the curriculum. | ALTEX 20090101 |
The role of aldosterone blockade in end-stage renal disease. | Cardiology 20090101 |
Long-term low-dose spironolactone therapy is safe in oligoanuric hemodialysis patients. | Cardiology 20090101 |
Effects of aldosterone blockade on left ventricular function and clinical status during acute myocardial infarction. | Scandinavian journal of clinical and laboratory investigation 20090101 |
Graz Endocrine Causes of Hypertension (GECOH) study: a diagnostic accuracy study of aldosterone to active renin ratio in screening for primary aldosteronism. | BMC endocrine disorders 20090101 |
Androgen dependence of hirsutism, acne, and alopecia in women: retrospective analysis of 228 patients investigated for hyperandrogenism. | Medicine 20090101 |
Diuretics. | British journal of hospital medicine (London, England : 2005) 20090101 |
Effect of aldosterone antagonism on exercise tolerance, Doppler diastolic function, and quality of life in older women with diastolic heart failure. | Congestive heart failure (Greenwich, Conn.) 20090101 |
[The absence of haptic perception in laparoscopic cholecystectomy--risk factor for biliary lesions]. | Chirurgia (Bucharest, Romania : 1990) 20090101 |
The frequency of adverse drug reaction related admissions according to method of detection, admission urgency and medical department specialty. | BMC clinical pharmacology 20090101 |
The systematic guideline review: method, rationale, and test on chronic heart failure. | BMC health services research 20090101 |
Fourteen-year follow-up in a teenager with congenital long QT syndrome masquerading as idiopathic generalized epilepsy. | Journal of the American Board of Family Medicine : JABFM 20090101 |
Candesartan cilexetil in the treatment of chronic heart failure. | Vascular health and risk management 20090101 |
Redefining the role of thiazolidinediones in the management of type 2 diabetes. | Vascular health and risk management 20090101 |
Angiotensin receptor blockers for the reduction of proteinuria in diabetic patients with overt nephropathy: results from the AMADEO study. | Vascular health and risk management 20090101 |
PCOS. | BMJ clinical evidence 20090101 |
Low-dose spironolactone: effects on artery-to-artery vein grafts and percutaneous coronary intervention sites. | American journal of therapeutics 20090101 |
Peritoneal mesothelial cells as a target of local aldosterone action: upregulation of connective tissue growth factor expression via serum- and glucocorticoid-inducible protein kinase 1. | Kidney & blood pressure research 20090101 |
Can tomato juice be used for prophylaxis in recurrent stone formers? | Indian journal of urology : IJU : journal of the Urological Society of India 20090101 |
Ascites: pathogenesis and therapeutic principles. | Scandinavian journal of gastroenterology 20090101 |
Safety, efficacy and patient acceptability of drospirenone and estradiol in the treatment of menopausal vasomotor symptoms: a review. | Clinical interventions in aging 20090101 |
[A mourning case that referred with sexual identity disorder secondary to a general medical condition]. | Turk psikiyatri dergisi = Turkish journal of psychiatry 20090101 |
Direct aldosterone action as a profibrotic factor via ROS-mediated SGK1 in peritoneal fibroblasts. | Kidney & blood pressure research 20090101 |
The psychometric validation of a US English satisfaction measure for patients with benign prostatic hyperplasia and lower urinary tract symptoms. | Health and quality of life outcomes 20090101 |
Structured chronic primary care and health-related quality of life in chronic heart failure. | BMC health services research 20090101 |
[Effectiveness of nutritional support for the liver-cell deficiency in the liver cirrhosis]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101 |
Cardiac magnetic resonance imaging in hemodialysis patients. | Journal of nephrology 20090101 |
Food for thought... on evidence-based toxicology. | ALTEX 20090101 |
The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation. | ALTEX 20090101 |
Quantitation of angiogenesis and antiangiogenesis in vivo, ex vivo and in vitro - an overview. | ALTEX 20090101 |
Animal and non-animal experiments in nanotechnology - the results of a critical literature survey. | ALTEX 20090101 |
Surgery of secondary mitral insufficiency in patients with impaired left ventricular function. | Journal of cardiothoracic surgery 20090101 |
Minimal change nephrotic syndrome in an 82 year old patient following a tetanus-diphteria-poliomyelitis-vaccination. | BMC nephrology 20090101 |
Inappropriate drug dosage adjustments in patients with renal impairment. | Journal of nephrology 20090101 |
[Study of the ocular findings in Stevens-Johnson syndrome patients from a tertiary ophthalmologic center]. | Arquivos brasileiros de oftalmologia 20090101 |
Triple therapy can achieve striking reductions in frusemide dosage. | Cardiology 20090101 |
Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: population based cohort study. | BMJ (Clinical research ed.) 20090101 |
Usefulness of NT-pro BNP monitoring to identify echocardiographic responders following cardiac resynchronization therapy. | Cardiovascular ultrasound 20090101 |
Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin. | PloS one 20090101 |
Mefenamic acid-induced bilateral transient myopia, secondary angle closure glaucoma and choroidal detachment. | Indian journal of ophthalmology 20090101 |
Management of ascites due to gastrointestinal malignancy. | Annals of Saudi medicine 20090101 |
The benefits and risks of testosterone replacement therapy: a review. | Therapeutics and clinical risk management 20090101 |
A comparative study of the prevalence of hyperkalemia with the use of angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers. | Therapeutics and clinical risk management 20090101 |
Successful tricuspid valve replacement in a patient with severe pulmonary arterial hypertension and preserved right ventricular systolic function. | Case reports in medicine 20090101 |
Predictors of hyperkalemia risk following hypertension control with aldosterone blockade. | American journal of nephrology 20090101 |
Cardiac sarcoidosis culminating in severe biventricular failure. | Case reports in medicine 20090101 |
Potential prescription patterns and errors in elderly adult patients attending public primary health care centers in Mexico City. | Clinical interventions in aging 20090101 |
Growing insights into the potential benefits and risks of activated protein C administration in sepsis: a review of preclinical and clinical studies. | Biologics : targets & therapy 20090101 |
[The antiproteinuric effect of the blockage of the renin-angiotensin-aldosterone system (RAAS) in obese patients. Which treatment option is the most effective? ]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20090101 |
Diabetic nephropathy. | Diabetology & metabolic syndrome 20090101 |
Severe hypokalemia, metabolic alkalosis and hypertension in a 54 year old male with ectopic ACTH syndrome: a case report. | Cases journal 20090101 |
Hypokalemia induced myopathy as first manifestation of primary hyperaldosteronism - an elderly patient with unilateral adrenal hyperplasia: a case report. | Cases journal 20090101 |
Failure of ultrasound to diagnose a giant ovarian cyst: a case report. | Cases journal 20090101 |
Hypokalaemia and cardiac arrest complicating vancomycin and furosemide therapy: a case report. | Cases journal 20090101 |
Mesothelioma of the testis and nephrotic syndrome: a case report. | Journal of medical case reports 20090101 |
Progressive visceral leishmaniasis misdiagnosed as cirrhosis of the liver: a case report. | Journal of medical case reports 20090101 |
Vancomycin-induced thrombocytopenia in a 60-year-old man: a case report. | Journal of medical case reports 20090101 |
Primary biliary cirrhosis presenting with ascites and a hepatic hydrothorax: a case report. | Journal of medical case reports 20090101 |
Visual hallucinations associated with varenicline: a case report. | Journal of medical case reports 20090101 |
Differential effects of 17beta-estradiol and of synthetic progestins on aldosterone-salt-induced kidney disease. | Toxicologic pathology 20090101 |
Should dermatologists prescribe hormonal contraceptives for acne? | Dermatologic therapy 20090101 |
Management of end-stage heart failure: a perspective on the Arab Gulf states. | Annals of Saudi medicine 20090101 |
Management of hypertension in the elderly patient. | Clinical interventions in aging 20090101 |
Spironolactone increases permeability of visceral sheep peritoneum. | Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20090101 |
Beta-2 adrenergic receptor gene polymorphisms Gln27Glu, Arg16Gly in patients with heart failure. | BMC cardiovascular disorders 20090101 |
A Case of Dilated Cardiomyopathy Associated with 3-Hydroxy-3-Methylglutaryl-Coenzyme A (HMG CoA) Lyase Deficiency. | Case reports in medicine 20090101 |
Food for thought ... on in silico methods in toxicology. | ALTEX 20090101 |
VirtualToxLab - in silico prediction of the toxic (endocrine-disrupting) potential of drugs, chemicals and natural products. Two years and 2,000 compounds of experience: a progress report. | ALTEX 20090101 |
Luminescent imaging technology as an opportunity to reduce and refine animal experiments: Light at the end of the tunnel? | ALTEX 20090101 |
Re-evaluation of animal numbers and costs for in vivo tests to accomplish REACH legislation requirements for chemicals - a report by the transatlantic think tank for toxicology (t(4)). | ALTEX 20090101 |
Comparison of metabolic stability and metabolite identification of 55 ECVAM/ICCVAM validation compounds between human and rat liver homogenates and microsomes - a preliminary analysis. | ALTEX 20090101 |
Alternatives to the use of animals in safety testing as required by the EU-Cosmetics Directive 2009. | ALTEX 20090101 |
Autonomic cardiovascular modulation. | IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society 20090101 |
Secondary adrenal insufficiency and primary antiphospholipid syndrome. | Internal medicine (Tokyo, Japan) 20090101 |
Incisional hernia as an unusual cause of hepatic encephalopathy in a 62-year-old man with cirrhosis: a case report. | Journal of medical case reports 20090101 |
Recurrent acute myocardial infarction with coronary artery aneurysm in a patient with Behçet's disease: a case report. | Journal of medical case reports 20090101 |
Antifibrotic effects of aldosterone receptor blocker (spironolactone) in patients with chronic kidney disease. | Renal failure 20090101 |
Left ventricular diastolic dysfunction of the cardiac surgery patient; a point of view for the cardiac surgeon and cardio-anesthesiologist. | Journal of cardiothoracic surgery 20090101 |
Radial dyssynchrony assessed by cardiovascular magnetic resonance in relation to left ventricular function, myocardial scarring and QRS duration in patients with heart failure. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20090101 |
Recurrent duodenal ulcer due to nonsteroidal anti-inflammatories following the suspension of antiulcer medication. | Clinical drug investigation 20090101 |
Failure of psychological interventions to lower blood pressure: a randomized controlled trial. | Open medicine : a peer-reviewed, independent, open-access journal 20090101 |
Sperm in peritoneal fluid from a man with ascites: a case report. | Cases journal 20090101 |
Persistent orocutaneous and anal fistulae induced by nicorandil: a case report. | Journal of medical case reports 20090101 |
De Toni-Debré-Fanconi syndrome in a patient with Kearns-Sayre syndrome: a case report. | Journal of medical case reports 20090101 |
Hereditary Hemorrhagic Telangiectasia Presenting as High Output Cardiac Failure during Pregnancy. | Cardiology research and practice 20090101 |
Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database. | BMJ (Clinical research ed.) 20090101 |
Safety and efficacy of testosterone gel in the treatment of male hypogonadism. | Clinical interventions in aging 20090101 |
Review of the treatment of acute coronary syndrome in elderly patients. | Clinical interventions in aging 20090101 |
Interspecies crosses: aspects of animal protection. | ALTEX 20090101 |
A case of brucellar spondylodiscitis involving the cervical spine. | Journal of back and musculoskeletal rehabilitation 20090101 |
Fast track liver resection: the effect of a comprehensive care package and analgesia with single dose intrathecal morphine with gabapentin or continuous epidural analgesia. | HPB surgery : a world journal of hepatic, pancreatic and biliary surgery 20090101 |
Effect of spironolactone on urinary protein excretion in patients with chronic kidney disease. | Renal failure 20090101 |
[The difficulties in differential diagnosis of primary aldosteronism subtypes in women with strokes at a young age]. | Endokrynologia Polska 20090101 |
Hirsutism in Kashmir: an etiological study. | Indian journal of dermatology 20090101 |
[Detection of selected diuretics in biological fluids by chromatography mass spectrometry]. | Sudebno-meditsinskaia ekspertiza 20090101 |
[Diastolic heart failure: are problems in its diagnosis and treatment solvable?]. | Terapevticheskii arkhiv 20090101 |
[Solubility enhancement with extrusion technology]. | Acta pharmaceutica Hungarica 20090101 |
A hypokalemic muscular weakness after licorice ingestion: a case report. | Cases journal 20090101 |
Adrenocortical carcinoma secreting cortisol, androgens and aldosterone: a case report. | Cases journal 20090101 |
[Prognostic significance of leukemia-associated phenotype in correlation with other biologic markers in acute myeloid leukemia patients]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20090101 |
[Does spironolactone use at arterial hypertension therapy protect endothelium also in smoking patients?]. | Przeglad lekarski 20090101 |
Medical treatment of Cushing's disease: Overview and recent findings. | International journal of general medicine 20090101 |
Food for thought ... on education in alternative methods in toxicology. | ALTEX 20090101 |
Development, validation and applications of the monocyte activation test for pyrogens based on human whole blood. | ALTEX 20090101 |
A model of isolated, autologously hemoperfused porcine slaughterhouse lungs. | ALTEX 20090101 |
Political incentives towards replacing animal testing in nanotechnology? | ALTEX 20090101 |
Long term cultures of primary human hepatocytes as an alternative to drug testing in animals. | ALTEX 20090101 |
Proposal for a Brazilian centre on alternative test methods. | ALTEX 20090101 |
Acute diastolic mitral regurgitation as a mechanism of left ventricular failure in a patient with normal systolic function. | Indian heart journal 20090101 |
Role of anxiety in the pathophysiology of irritable bowel syndrome: importance of the amygdala. | Frontiers in neuroscience 20090101 |
Exforge (amlodipine/valsartan combination) in hypertension: the evidence of its therapeutic impact. | Core evidence 20090101 |
Cardiorenal syndrome. | F1000 medicine reports 20090101 |
That which must not, can not be... A reply to the EChA and EDF responses to the REACH analysis of animal use and costs. | ALTEX 20090101 |
Safety, efficacy, actions, and patient acceptability of drospirenone/ethinyl estradiol contraceptive pills in the treatment of premenstrual dysphoric disorder. | International journal of women's health 20090101 |
Efficacy and safety of combined ethinyl estradiol/drospirenone oral contraceptives in the treatment of acne. | International journal of women's health 20090101 |
Viral cirrhosis: an overview of haemostatic alterations and clinical consequences. | Mediterranean journal of hematology and infectious diseases 20090101 |
An update on the management of acne vulgaris. | Clinical, cosmetic and investigational dermatology 20090101 |
Manifestation of renal disease in obesity: pathophysiology of obesity-related dysfunction of the kidney. | International journal of nephrology and renovascular disease 20090101 |
Clinical approach in treatment of resistant hypertension. | Integrated blood pressure control 20090101 |
Coronary artery grafting in infants. | Images in paediatric cardiology 20090101 |
Nucleic Acid-based Detection of Bacterial Pathogens Using Integrated Microfluidic Platform Systems. | Sensors (Basel, Switzerland) 20090101 |
Semiconductor quantum dots in chemical sensors and biosensors. | Sensors (Basel, Switzerland) 20090101 |
Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells. | Experimental cell research 20081210 |
[No effect of spironolactone on bulimia nervosa symptoms]. | Psychotherapie, Psychosomatik, medizinische Psychologie 20081201 |
Induction of hepatic glutathione S-transferases in male mice by prototypes of various classes of microsomal enzyme inducers. | Toxicological sciences : an official journal of the Society of Toxicology 20081201 |
Hydroxychloroquine-induced hyperpigmentation: the staining pattern. | Journal of cutaneous pathology 20081201 |
Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone. | Kidney international 20081201 |
Effect of spironolactone, potassium canrenoate and their common metabolite canrenone on serum digoxin measurement by digoxin III, a new digoxin immunoassay. | Therapeutic drug monitoring 20081201 |
Endocrine arterial hypertension: therapeutic approach in clinical practice. | Minerva endocrinologica 20081201 |
Eplerenone in patients with acute myocardial infarction complicated by heart failure. | Hypertension (Dallas, Tex. : 1979) 20081201 |
A patient with ectopic cortisol production derived from malignant testicular masses. | Nature clinical practice. Endocrinology & metabolism 20081201 |
Pilot randomised double-blind controlled trial of high-dose spironolactone in critically ill patients receiving a frusemide infusion. | Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20081201 |
Possible underlying mechanisms responsible for aldosterone and mineralocorticoid receptor-dependent renal injury. | Journal of pharmacological sciences 20081201 |
The relationship between heart rate reserve and oxygen uptake reserve in heart failure patients on optimized and non-optimized beta-blocker therapy. | Clinics (Sao Paulo, Brazil) 20081201 |
Hepatitis C infection and thyrotoxic periodic paralysis--a novel use of an old drug. | The American journal of the medical sciences 20081201 |
Expression of NAD(P)H oxidase subunits and their contribution to cardiovascular damage in aldosterone/salt-induced hypertensive rat. | Journal of Korean medical science 20081201 |
[Impact of patient compliance on the outcomes in hypertensive patients receiving hydrochlorothiazide based combination therapy with spironolactone or captopril]. | Zhonghua xin xue guan bing za zhi 20081201 |
Aldosterone induces collagen synthesis via activation of extracellular signal-regulated kinase 1 and 2 in renal proximal tubules. | Nephrology (Carlton, Vic.) 20081201 |
A thyrotoxicosis outbreak due to dietary pills in Paris. | Therapeutics and clinical risk management 20081201 |
Pathogenetic background for treatment of ascites and hepatorenal syndrome. | Hepatology international 20081201 |
Eplerenone inhibits the intracrine and extracellular actions of angiotensin II on the inward calcium current in the failing heart. On the presence of an intracrine renin angiotensin aldosterone system. | Regulatory peptides 20081129 |
High-performance liquid chromatography-diode array and electrospray-mass spectrometry analysis of non-allowed substances in cosmetic products for preventing hair loss and other hormone-dependent skin diseases. | Journal of pharmaceutical and biomedical analysis 20081104 |
Use of photosensitising diuretics and risk of skin cancer: a population-based case-control study. | British journal of cancer 20081104 |
Aldosterone-induced changes in the cardiac L-type Ca(2+) current can be prevented by antioxidants in vitro and are absent in rats on low salt diet. | Pflugers Archiv : European journal of physiology 20081101 |
Blood pressure versus direct mineralocorticoid effects on kidney inflammation and fibrosis in DOCA-salt hypertension. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081101 |
DNA damage in workers occupationally exposed to pesticide mixtures. | Journal of applied toxicology : JAT 20081101 |
Genomic and nongenomic dose-dependent biphasic effect of aldosterone on Na+/H+ exchanger in proximal S3 segment: role of cytosolic calcium. | American journal of physiology. Renal physiology 20081101 |
Spironolactone attenuates oxidative stress in patients with chronic kidney disease. | Hypertension (Dallas, Tex. : 1979) 20081101 |
Simultaneous analysis of thirteen diuretics residues in bovine milk by ultra-performance liquid chromatography/tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20081101 |
Risk of hyperkalemia in women taking ethinylestradiol/drospirenone and other oral contraceptives. | Contraception 20081101 |
Exploring the potential synergistic action of spironolactone on nitric oxide-enhancing therapy: insights from the African-American Heart Failure Trial. | Journal of cardiac failure 20081101 |
Safety of spironolactone use in ambulatory heart failure patients. | Clinical cardiology 20081101 |
Effect of spironolactone therapy on albuminuria in patients with type 2 diabetes treated with angiotensin-converting enzyme inhibitors. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20081101 |
A randomised, controlled, double-blind, cross-over pilot study assessing the effects of spironolactone, losartan and their combination on heart rate variability and QT dispersion in patients with chronic heart failure. | Cardiovascular journal of Africa 20081101 |
Natriuretic Peptide testing in primary care. | Current cardiology reviews 20081101 |
Primary hyperaldosteronism in a domestic ferret with an adrenocortical adenoma. | Journal of the American Veterinary Medical Association 20081015 |
Serum potassium and clinical outcomes in the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS). | Circulation 20081014 |
Hyperkalemia associated with inhibitors of the renin-angiotensin-aldosterone system: balancing risk and benefit. | Circulation 20081014 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. | Journal of medicinal chemistry 20081009 |
[Spironolactone in patients with resistant hypertension]. | Medicina clinica 20081004 |
[Role of antialdosteronics in the treatment of refractory hypertension]. | Medicina clinica 20081004 |
[Heart failure in men and women: important differences in the diagnostic workup and treatment]. | Nederlands tijdschrift voor geneeskunde 20081004 |
Aldosterone induces cardiotrophin-1 expression in HL-1 adult cardiomyocytes. | Endocrinology 20081001 |
The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy. | European heart journal 20081001 |
Adrenalectomy improves arterial stiffness in primary aldosteronism. | American journal of hypertension 20081001 |
Glucocorticoid signaling and exercise-induced downregulation of the mineralocorticoid receptor in the induction of adult mouse dentate neurogenesis by treadmill running. | Psychoneuroendocrinology 20081001 |
Exposure of the elderly to potential nephrotoxic drug combinations in Belgium. | Pharmacoepidemiology and drug safety 20081001 |
Conversion of optically active hydrindanone to (+)-bakkenolide-A. | Chemical & pharmaceutical bulletin 20081001 |
[Pharmacology profile and clinical findings of Selara Tablets (eplerenone)]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20081001 |
Resolution of refractory ascites after transcoronary septal ablation for hypertrophic obstructive cardiomyopathy in a cirrhotic patient. | Zeitschrift fur Gastroenterologie 20081001 |
Severe macular edema induced by pioglitazone in a patient with diabetic retinopathy: a case study. | Vascular health and risk management 20081001 |
NF-kappaB inhibits sodium transport via down-regulation of SGK1 in renal collecting duct principal cells. | The Journal of biological chemistry 20080912 |
Aliskiren combined with losartan in diabetes and nephropathy. | The New England journal of medicine 20080904 |
Regression of left ventricular hypertrophy and aortic remodelling in NO-deficient hypertensive rats: effect of L-arginine and spironolactone. | Acta physiologica (Oxford, England) 20080901 |
Triple pharmacological blockade of the renin-angiotensin-aldosterone system in nondiabetic CKD: an open-label crossover randomized controlled trial. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20080901 |
Inhibition of mineralocorticoid receptors with eplerenone alleviates short-term cyclosporin A nephrotoxicity in conscious rats. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080901 |
Differential roles of cardiomyocyte and macrophage peroxisome proliferator-activated receptor gamma in cardiac fibrosis. | Diabetes 20080901 |
Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline. | The Journal of clinical endocrinology and metabolism 20080901 |
The impact of pre-existing heart failure on pneumonia prognosis: population-based cohort study. | Journal of general internal medicine 20080901 |
Aldosterone synthase inhibition improves cardiovascular function and structure in rats with heart failure: a comparison with spironolactone. | European heart journal 20080901 |
Aldosterone increases KCa1.1 (BK) channel-mediated colonic K+ secretion. | The Journal of physiology 20080901 |
Dilated cardiomyopathy: an unusual complication of clozapine therapy. | Nature clinical practice. Cardiovascular medicine 20080901 |
Aldosterone induces interleukin-18 through endothelin-1, angiotensin II, Rho/Rho-kinase, and PPARs in cardiomyocytes. | American journal of physiology. Heart and circulatory physiology 20080901 |
Evaluation of nanosuspensions for absorption enhancement of poorly soluble drugs: in vitro transport studies across intestinal epithelial monolayers. | The AAPS journal 20080901 |
Association of blood pressure and its evolving changes with the survival of patients with heart failure. | Journal of cardiac failure 20080901 |
Mineralocorticoid receptor antagonists and endothelial function. | Current opinion in investigational drugs (London, England : 2000) 20080901 |
Hormonal therapy for acne. | Seminars in cutaneous medicine and surgery 20080901 |
Hyperkalemia during spironolactone use in patients with decompensated heart failure. | Arquivos brasileiros de cardiologia 20080901 |
Hypertension-induced renal fibrosis and spironolactone response vary by rat strain and mineralocorticoid receptor gene expression. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20080901 |
Effect of single treatment with the antihypertensive drug eplerenone on hormone levels and anxiety-like behaviour in rats. | Endocrine regulations 20080901 |
Cost-effectiveness analysis of aldosterone blockade with eplerenone in patients with heart failure after acute myocardial infarction in the French context: the EPHESUS study. | Archives of cardiovascular diseases 20080901 |
Aldosterone modifies hemostasis via upregulation of the protein-C receptor in human vascular endothelium. | Biochemical and biophysical research communications 20080822 |
Diastolic dysfunction and atrial fibrillation. | Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20080801 |
Effect of aldosterone on isolated human penile corpus cavernosum tissue. | BJU international 20080801 |
The role of mineralocorticoid receptor expression in brain remodeling after cerebral ischemia. | Endocrinology 20080801 |
Spironolactone use and the risk of upper gastrointestinal bleeding: a population-based case-control study. | British journal of clinical pharmacology 20080801 |
Carbenoxolone impairs LTP and blocks NMDA receptors in murine hippocampus. | Neuropharmacology 20080801 |
History of hypertension and eplerenone in patients with acute myocardial infarction complicated by heart failure. | Hypertension (Dallas, Tex. : 1979) 20080801 |
Cardiac benefits of mineralocorticoid receptor inhibition in renal failure. | Hypertension (Dallas, Tex. : 1979) 20080801 |
Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and prevents oxidative stress in uremic rats. | Hypertension (Dallas, Tex. : 1979) 20080801 |
Salt excess causes left ventricular diastolic dysfunction in rats with metabolic disorder. | Hypertension (Dallas, Tex. : 1979) 20080801 |
Stroke therapy: is spironolactone the Holy Grail? | Endocrinology 20080801 |
Aldosterone, but not angiotensin II, reduces angiotensin converting enzyme 2 gene expression levels in cultured neonatal rat cardiomyocytes. | Circulation journal : official journal of the Japanese Circulation Society 20080801 |
Adolescent female acne: etiology and management. | Journal of pediatric and adolescent gynecology 20080801 |
A randomized trial of the aldosterone-receptor antagonist eplerenone in asymptomatic moderate-severe aortic stenosis. | American heart journal 20080801 |
The accuracy of reporting of the hypertensive disorders of pregnancy in population health data. | Hypertension in pregnancy 20080801 |
Heart rate dynamics during a treadmill cardiopulmonary exercise test in optimized beta-blocked heart failure patients. | Clinics (Sao Paulo, Brazil) 20080801 |
Delayed-onset hepatic encephalopathy induced by zolpidem: a case report. | Clinics (Sao Paulo, Brazil) 20080801 |
Description of a chronic heart failure service model and review of pharmacotherapy in a district general hospital in comparison to Scottish Intercollegiate Guideline Network (SIGN) guidelines. | Scottish medical journal 20080801 |
Improved analytical validation and pharmacokinetics of valsartan using HPLC with UV detection. | Archives of pharmacal research 20080801 |
Case of Budd-Chiari syndrome 3 months after vaginal delivery. | The journal of obstetrics and gynaecology research 20080801 |
A 41-year-old man with polyarthritis and severe autonomic neuropathy. | Therapeutics and clinical risk management 20080801 |
Morphological and molecular changes of the myocardium after left ventricular mechanical support. | Current cardiology reviews 20080801 |
Progression of renal dysfunction in patients with cardiovascular disease. | Current cardiology reviews 20080801 |
Spironolactone exhibits direct renoprotective effects and inhibits renal renin-angiotensin-aldosterone system in diabetic rats. | European journal of pharmacology 20080728 |
[Ascites]. | Praxis 20080709 |
Fracture risk in men with congestive heart failure risk reduction with spironolactone. | Journal of the American College of Cardiology 20080708 |
Vasoconstrictor effect of aldosterone via angiotensin II type 1 (AT1) receptor: possible role of AT1 receptor dimerization. | Cardiovascular research 20080701 |
Effects of a novel Y5 antagonist in obese mice: combination with food restriction or sibutramine. | Obesity (Silver Spring, Md.) 20080701 |
Regression of glomerulosclerosis in subtotally nephrectomized rats: effects of monotherapy with losartan, spironolactone, and their combination. | American journal of physiology. Renal physiology 20080701 |
Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat. | American journal of physiology. Endocrinology and metabolism 20080701 |
Induction of oscillatory ventilation pattern using dynamic modulation of heart rate through a pacemaker. | American journal of physiology. Regulatory, integrative and comparative physiology 20080701 |
Aldosterone induces mesangial cell apoptosis both in vivo and in vitro. | American journal of physiology. Renal physiology 20080701 |
Proteins interact with the cytosolic mineralocorticoid receptor depending on the ligand. | American journal of physiology. Heart and circulatory physiology 20080701 |
Hypertension induces somatic cellular senescence in rats and humans by induction of cell cycle inhibitor p16INK4a. | Hypertension (Dallas, Tex. : 1979) 20080701 |
Awareness and perception of heart failure among European cardiologists, internists, geriatricians, and primary care physicians. | European heart journal 20080701 |
Effects of satavaptan, a selective vasopressin V(2) receptor antagonist, on ascites and serum sodium in cirrhosis with hyponatremia: a randomized trial. | Hepatology (Baltimore, Md.) 20080701 |
Paradoxical mineralocorticoid receptor activation and left ventricular diastolic dysfunction under high oxidative stress conditions. | Journal of hypertension 20080701 |
Management strategies for premenstrual syndrome/premenstrual dysphoric disorder. | The Annals of pharmacotherapy 20080701 |
Depression worsens outcomes in elderly patients with heart failure: an analysis of 48,117 patients in a community setting. | European journal of heart failure 20080701 |
Comparison of one-year outcome (death and rehospitalization) in hospitalized heart failure patients with left ventricular ejection fraction >50% versus those with ejection fraction <50%. | The American journal of cardiology 20080701 |
Primary aldosteronism and aldosterone-associated hypertension. | Journal of clinical pathology 20080701 |
Spironolactone alleviates late cardiac remodeling after left ventricular restoration surgery. | The Journal of thoracic and cardiovascular surgery 20080701 |
Hydroxyurea associated with concomitant occurrence of diffuse longitudinal melanonychia and multiple squamous cell carcinomas in an elderly subject. | Clinical therapeutics 20080701 |
Diagnosis of hypokalemia: a problem-solving approach to clinical cases. | Iranian journal of kidney diseases 20080701 |
Familial mineralocorticoid induced hypertension in the sultanate of oman. | Sultan Qaboos University medical journal 20080701 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study. | Lancet (London, England) 20080607 |
Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesion. | Circulation research 20080606 |
Effect of dexamethasone on voltage-gated Na+ channel in cultured human bronchial smooth muscle cells. | Life sciences 20080606 |
Eplerenone improves prognosis in postmyocardial infarction diabetic patients with heart failure: results from EPHESUS. | Diabetes, obesity & metabolism 20080601 |
Genomic regulation of intestinal amino acid transporters by aldosterone. | Molecular and cellular biochemistry 20080601 |
Aldosterone and TGF-beta1 synergistically increase PAI-1 and decrease matrix degradation in rat renal mesangial and fibroblast cells. | American journal of physiology. Renal physiology 20080601 |
Aldosterone and the autocrine modulation of potassium currents and oxidative stress in the diabetic rat heart. | British journal of pharmacology 20080601 |
Role of the renin-angiotensin-aldosterone system in collecting duct-derived endothelin-1 regulation of blood pressure. | Canadian journal of physiology and pharmacology 20080601 |
Cocaine decreases the expression of PSA-NCAM protein and attenuates long-term potentiation via glucocorticoid receptors in the rat dentate gyrus. | The European journal of neuroscience 20080601 |
The specific mineralocorticoid receptor blocker eplerenone attenuates left ventricular remodeling in mice lacking the gene encoding guanylyl cyclase-A. | Hypertension research : official journal of the Japanese Society of Hypertension 20080601 |
[Prevention of left ventricular remodeling after myocardial infarction: efficacy of physical training]. | Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20080601 |
Treating resistant hypertension with spironolactone. | Current hypertension reports 20080601 |
Obesity, sleep apnea, aldosterone, and hypertension. | Current hypertension reports 20080601 |
Fibrosis in diabetes complications: pathogenic mechanisms and circulating and urinary markers. | Vascular health and risk management 20080601 |
Effect of spironolactone on hypertrophy of left ventricular myocardium in wistar rats with experimental uremia. | Bulletin of experimental biology and medicine 20080601 |
[Misdiagnosed emergency: heart failure symptoms after infarct. Rapid aldosterone block can safe the tired heart]. | MMW Fortschritte der Medizin 20080529 |
Are we missing a mineralocorticoid in teleost fish? Effects of cortisol, deoxycorticosterone and aldosterone on osmoregulation, gill Na+,K+ -ATPase activity and isoform mRNA levels in Atlantic salmon. | General and comparative endocrinology 20080515 |
Use of human spironolactone in dogs with heart failure. | The Veterinary record 20080503 |
Use of human spironolactone in dogs with heart failure. | The Veterinary record 20080503 |
A systematic review of commonly used medical treatments for hirsutism in women. | Clinical endocrinology 20080501 |
Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes. | Pflugers Archiv : European journal of physiology 20080501 |
Spironolactone and gastrointestinal bleeding: a population based study. | Pharmacoepidemiology and drug safety 20080501 |
Assessment, diagnosis and treatment of a patient with hirsutism. | Nature clinical practice. Endocrinology & metabolism 20080501 |
Therapeutic strategies to slow chronic kidney disease progression. | Pediatric nephrology (Berlin, Germany) 20080501 |
Glucocorticoid-related signaling effects in vascular smooth muscle cells. | Hypertension (Dallas, Tex. : 1979) 20080501 |
Spironolactone for poorly controlled hypertension in type 2 diabetes: conflicting effects on blood pressure, endothelial function, glycaemic control and hormonal profiles. | Diabetologia 20080501 |
Mineralocorticoid receptor blockade ameliorates peritoneal fibrosis in new rat peritonitis model. | American journal of physiology. Renal physiology 20080501 |
Eplerenone in the treatment of Gitelman's syndrome. | Internal medicine journal 20080501 |
Plasma concentrations of matrix metalloproteinase-2, tissue inhibitor of metalloproteinase-1 and osteopontin reflect severity of heart failure in DOCA-salt hypertensive rat. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20080501 |
Sub-chronic stimulation of glucocorticoid receptor impairs and mineralocorticoid receptor protects cytosolic Ca2+ responses to glucose in pancreatic beta-cells. | The Journal of endocrinology 20080501 |
Primary prophylaxis of esophageal variceal bleeding in cirrhosis. | Gastroenterologie clinique et biologique 20080501 |
The effects of nesiritide on renal function and diuretic responsiveness in acutely decompensated heart failure patients with renal dysfunction. | Journal of cardiac failure 20080501 |
Aldosterone-to-renin ratio as a screening test for primary aldosteronism--the Dutch ARRAT Study. | The Netherlands journal of medicine 20080501 |
Influence of spironolactone therapy on thiamine blood levels in patients with heart failure. | Arquivos brasileiros de cardiologia 20080501 |
Solubilisation of drugs in worm-like micelles of block copolymers of ethylene oxide and 1,2-butylene oxide in aqueous solution. | International journal of pharmaceutics 20080416 |
Use of human spironolactone in dogs with heart failure. | The Veterinary record 20080405 |
Synthesis and spin-trapping properties of a new spirolactonyl nitrone. | The Journal of organic chemistry 20080404 |
Clinical review: Antiandrogens for the treatment of hirsutism: a systematic review and metaanalyses of randomized controlled trials. | The Journal of clinical endocrinology and metabolism 20080401 |
Clinical review: Insulin sensitizers for the treatment of hirsutism: a systematic review and metaanalyses of randomized controlled trials. | The Journal of clinical endocrinology and metabolism 20080401 |
A lifetime of aldosterone excess: long-term consequences of altered regulation of aldosterone production for cardiovascular function. | Endocrine reviews 20080401 |
Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response. | Hypertension (Dallas, Tex. : 1979) 20080401 |
Translational research goes both ways: lessons from clinical studies. | Clinical and experimental pharmacology & physiology 20080401 |
Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. | Chemical research in toxicology 20080401 |
Thiazolidinedione insulin sensitizers and the heart: a tale of two organs? | Diabetes, obesity & metabolism 20080401 |
No effect of spironolactone on bulimia nervosa symptoms. | Journal of clinical psychopharmacology 20080401 |
A dynamic comparative study concerning the effects of angiotensin-converting enzyme inhibitors and aldosterone receptor blockers on the fibrinolytic system. | Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20080401 |
Effects of additive therapy with spironolactone on proteinuria in diabetic patients already on ACE inhibitor or ARB therapy: results of a randomized, placebo-controlled, double-blind, crossover trial. | Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20080401 |
Comparison of the clinical efficacy of flutamide and spironolactone plus ethinyloestradiol/cyproterone acetate in the treatment of hirsutism: a randomised controlled study. | Advances in therapy 20080401 |
Well tolerated spironolactone-related hyponatremia. | Journal of clinical hypertension (Greenwich, Conn.) 20080401 |
A comparison of the aldosterone-blocking agents eplerenone and spironolactone. | Clinical cardiology 20080401 |
Hospital management of heart failure: improvement but still room for improvement at discharge.. | Archives of cardiovascular diseases 20080401 |
Evaluation of heart failure management in a Military Hospital. | Archives of cardiovascular diseases 20080401 |
Use of ethinylestradiol/drospirenone combination in patients with the polycystic ovary syndrome. | Therapeutics and clinical risk management 20080401 |
Hemodynamic effects of propranolol with spironolactone in patients with variceal bleeds: a randomized controlled trial. | World journal of gastroenterology 20080328 |
A review of hormonal therapy for female pattern (androgenic) alopecia. | Dermatology online journal 20080315 |
Variations in 123I-metaiodobenzylguanidine (MIBG) late heart mediastinal ratios in chronic heart failure: a need for standardisation and validation. | European journal of nuclear medicine and molecular imaging 20080301 |
Hypertension in children with chronic kidney disease: pathophysiology and management. | Pediatric nephrology (Berlin, Germany) 20080301 |
Hypophyseal corticosteroids stimulate somatotrope differentiation in the embryonic chicken pituitary gland. | Histochemistry and cell biology 20080301 |
Aldosterone induces superoxide generation via Rac1 activation in endothelial cells. | Endocrinology 20080301 |
Eplerenone potentiates the antiproteinuric effects of enalapril in experimental nephrotic syndrome. | American journal of physiology. Renal physiology 20080301 |
Oxidative stress and the genomic regulation of aldosterone-stimulated NHE1 activity in SHR renal proximal tubular cells. | Molecular and cellular biochemistry 20080301 |
Chylous ascites in a patient with mesenteric panniculits. | Journal of clinical gastroenterology 20080301 |
Addition of eplerenone to an angiotensin-converting enzyme inhibitor effectively improves nitric oxide bioavailability. | Hypertension (Dallas, Tex. : 1979) 20080301 |
Spironolactone suppresses peritubular capillary loss and prevents deoxycorticosterone acetate/salt-induced tubulointerstitial fibrosis. | Hypertension (Dallas, Tex. : 1979) 20080301 |
Premicroalbuminuria in women with polycystic ovary syndrome: a metabolic risk marker. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20080301 |
Spironolactone versus eplerenone for the treatment of idiopathic hyperaldosteronism. | Expert opinion on pharmacotherapy 20080301 |
Mechanisms and treatment of resistant hypertension. | Journal of clinical hypertension (Greenwich, Conn.) 20080301 |
Role of androgens, progestins and tibolone in the treatment of menopausal symptoms: a review of the clinical evidence. | Clinical interventions in aging 20080301 |
Carvedilol in the treatment of elderly patients with chronic heart failure. | Clinical interventions in aging 20080301 |
The relationship between aldosterone to renin ratio and RI value of the uterine artery in the preeclamptic patient vs. normal pregnancy. | Yonsei medical journal 20080227 |
Torasemide, a long-acting loop diuretic, reduces the progression of myocarditis to dilated cardiomyopathy. | European journal of pharmacology 20080226 |
Letter regarding article by Hood et al, 'The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio'. | Circulation 20080205 |
Outpatient monitoring and treatment of chronic heart failure guided by amino-terminal pro-B-type natriuretic peptide measurement. | The American journal of cardiology 20080204 |
An anti-immobility effect of exogenous corticosterone in mice. | European journal of pharmacology 20080202 |
Pharmacological profile of the new inotropic agent AT-11. | European journal of pharmacology 20080202 |
Willingness to pay for a reduction in mortality risk after a myocardial infarction: an application of the contingent valuation method to the case of eplerenone. | The European journal of health economics : HEPAC : health economics in prevention and care 20080201 |
Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cells. | Journal of cellular biochemistry 20080201 |
Aldosterone and amiloride alter ENaC abundance in vascular endothelium. | Pflugers Archiv : European journal of physiology 20080201 |
Study of the use of a spironolactone and angiotensin-converting enzyme inhibitor combination: a population-based analysis. | Pharmacoepidemiology and drug safety 20080201 |
The heart in transfusion dependent homozygous thalassaemia today--prediction, prevention and management. | European journal of haematology 20080201 |
Osteopontin in rat renal fibroblasts: functional properties and transcriptional regulation by aldosterone. | Hypertension (Dallas, Tex. : 1979) 20080201 |
Selective mineralocorticoid receptor blocker eplerenone reduces resistance artery stiffness in hypertensive patients. | Hypertension (Dallas, Tex. : 1979) 20080201 |
Efficacy and tolerability of adding an angiotensin receptor blocker in patients with heart failure already receiving an angiotensin-converting inhibitor plus aldosterone antagonist, with or without a beta blocker. Findings from the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM)-Added trial. | European journal of heart failure 20080201 |
Heart failure with preserved ejection fraction: clinical characteristics of 4133 patients enrolled in the I-PRESERVE trial. | European journal of heart failure 20080201 |
Isolated left ventricular noncompaction: unusual cause of decompensated heart failure and indication of heart transplantation in the early infancy--case report and literature review. | Clinics (Sao Paulo, Brazil) 20080201 |
Ovarian hyperthecosis and response to antiandrogens: An uncommon presentation of a common disorder. | Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20080201 |
Candesartan in heart failure: assessment of reduction in mortality and morbidity (CHARM) and resource utilization and costs in Italy. | Vascular health and risk management 20080201 |
[Antialdosteronic agents: their role in heart failure]. | Medicina clinica 20080119 |
Cardiovascular outcomes in patients with primary aldosteronism after treatment. | Archives of internal medicine 20080114 |
Effects of spironolactone on electrical and structural remodeling of atrium in congestive heart failure dogs. | Chinese medical journal 20080105 |
A disorder of sympathomimetic amines leading to increased vascular permeability may be the etiologic factor in various treatment refractory health problems in women. | Medical hypotheses 20080101 |
Efficacy and tolerance of acne treatment using both spironolactone and a combined contraceptive containing drospirenone. | Journal of the American Academy of Dermatology 20080101 |
The significance of compliance and persistence in the treatment of diabetes, hypertension and dyslipidaemia: a review. | International journal of clinical practice 20080101 |
Tissue distribution, ontogeny, and regulation of aldehyde dehydrogenase (Aldh) enzymes mRNA by prototypical microsomal enzyme inducers in mice. | Toxicological sciences : an official journal of the Society of Toxicology 20080101 |
Bartter syndrome and cholelithiasis in an infant: is this a mere coincidence? | European journal of pediatrics 20080101 |
Combination of clonidine and diuretic in cirrhotic ascites with activated sympathetic nervous system: Would it be a magical bullet? | Hepatology (Baltimore, Md.) 20080101 |
Drug Insight: eplerenone, a mineralocorticoid-receptor antagonist. | Nature clinical practice. Endocrinology & metabolism 20080101 |
Eplerenone after myocardial infarction? | Drug and therapeutics bulletin 20080101 |
[In-vitro evaluation of cinnarizine as a competing agent to beta-cyclodextrin inclusion complexes: effect of cinnarizine on the membrane permeation rate of progesterone from its beta-cyclodextrin inclusion complex]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080101 |
Chylous ascites following radical nephrectomy: a case report. | Journal of medical case reports 20080101 |
The role of aldosterone blockade in murine lupus nephritis. | Arthritis research & therapy 20080101 |
Dietary potassium supplementation improves vascular structure and ameliorates the damage caused by cerebral ischemia in normotensive rats. | Nutrition & metabolism 20080101 |
Increasing exposure to drug-drug interactions between 1992 and 2005 in people aged > or = 55 years. | Drugs & aging 20080101 |
[Effect of long term therapy with spironolactone on parameters of 24-hour heart rhythm variability and ventricular arrhythmias in patients with heart failure receiving optimal therapy]. | Kardiologiia 20080101 |
Effects of spironolactone in an experimental model of chronic cyclosporine nephrotoxicity. | Transplantation proceedings 20080101 |
Genetic and chemical modifiers of a CUG toxicity model in Drosophila. | PloS one 20080101 |
Development of a simplified assay for determination of the antimineralocorticoid activity of compounds dosed in rats. | Journal of pharmacological and toxicological methods 20080101 |
Oral contraceptives: mechanism of action, dosing, safety, and efficacy. | Cutis 20080101 |
Tailoring individualized treatment plans for acne. | Cutis 20080101 |
Effect of spironolactone on diastolic function and left ventricular mass in Maine Coon cats with familial hypertrophic cardiomyopathy. | Journal of veterinary internal medicine 20080101 |
Cardiac fibrosis in the elderly, normotensive athlete: case report and review of the literature. | Diagnostic pathology 20080101 |
Effect of renin-angiotensin-aldosterone system triple blockade on non-diabetic renal disease: addition of an aldosterone blocker, spironolactone, to combination treatment with an angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker. | Hypertension research : official journal of the Japanese Society of Hypertension 20080101 |
Clinical impact of adherence to guidelines on the outcome of chronic heart failure in Japan. | International heart journal 20080101 |
Food for thought... on animal tests. | ALTEX 20080101 |
Food for thought... on the real success of 3R approaches. | ALTEX 20080101 |
Human hepatocytes as an effective alternative experimental system for the evaluation of human drug properties: general concepts and assay procedures. | ALTEX 20080101 |
In vitro evaluation of human xenobiotic toxicity: scientific concepts and the novel integrated discrete multiple cell co-culture (IdMOC) technology. | ALTEX 20080101 |
An in vitro model for the comparative evaluation of bone seeking pharmaceuticals. | ALTEX 20080101 |
Russia: update on animal experiments and alternatives in education. | ALTEX 20080101 |
[An essay on the topicality and problem complex. Ethics of the Reverence for Life]. | ALTEX 20080101 |
Two elderly patients with mineralocorticoid excess due to 11 beta-hydroxysteroid dehydrogenase type 2 (11 beta-HSD2) impairment. | Internal medicine (Tokyo, Japan) 20080101 |
Practical aspects in the management of hypokalemic periodic paralysis. | Journal of translational medicine 20080101 |
ALTEX: Alternatives to Animal Experimentation. | ALTEX 20080101 |
Bioequivalence assessment of two formulations of spironolactone in Chinese healthy male volunteers. | Arzneimittel-Forschung 20080101 |
Plasma 11-deoxycorticosterone (DOC) and mineralocorticoid receptor testicular expression during rainbow trout Oncorhynchus mykiss spermiation: implication with 17alpha, 20beta-dihydroxyprogesterone on the milt fluidity? | Reproductive biology and endocrinology : RB&E 20080101 |
Single ventricle with persistent truncus arteriosus as two rare entities in an adult patient: a case report. | Journal of medical case reports 20080101 |
NS1 specific CD8+ T-cells with effector function and TRBV11 dominance in a patient with parvovirus B19 associated inflammatory cardiomyopathy. | PloS one 20080101 |
Comparative actions of progesterone, medroxyprogesterone acetate, drospirenone and nestorone on breast cancer cell migration and invasion. | BMC cancer 20080101 |
Safety profile of L-arginine infusion in moderately severe falciparum malaria. | PloS one 20080101 |
Food for thought ... on the evolution of toxicology and the phasing out of animal testing. | ALTEX 20080101 |
The dawning of a new age of toxicology. | ALTEX 20080101 |
An in vitro assay to screen for the sensitizing potential of xenobiotics. | ALTEX 20080101 |
Refinement and reduction in animal experimentation: options for new imaging techniques. | ALTEX 20080101 |
An animal welfare perspective on animal testing of GMO crops. | ALTEX 20080101 |
The effect of aldosterone antagonist in experimental nephropathy induced by cyclosporine A. | Renal failure 20080101 |
Practice characteristics and prescribing of cardiovascular drugs in areas with higher risk of CHD in Scotland: cross-sectional study. | International journal for equity in health 20080101 |
Pseudoaldosteronism caused by combined administration of cilostazol and glycyrrhizin. | Internal medicine (Tokyo, Japan) 20080101 |
[Thermosensitive polymers in drug form technology. II. Possibilities of use of thermosensitive polymers as active substance carriers]. | Polimery w medycynie 20080101 |
The tailored medical therapy in patients with advanced heart failure referred for cardiac transplantation. | Transplantation proceedings 20080101 |
[Triple-negative breast cancer--towards a new entity]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101 |
[Gastric lymphoma. Morphological and immunohistochemical study]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101 |
Renal and vascular mechanisms of thiazolidinedione-induced fluid retention. | PPAR research 20080101 |
Food for thought ... on alternative methods for cosmetics safety testing. | ALTEX 20080101 |
The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy. | ALTEX 20080101 |
A newly developed in vitro model of the human epithelial airway barrier to study the toxic potential of nanoparticles. | ALTEX 20080101 |
Reverse transcriptase activity of hepatitis B virus polymerase in eukaryotic cell extracts in vitro. | ALTEX 20080101 |
Non-animal methodologies within biomedical research and toxicity testing. | ALTEX 20080101 |
A review of national public funding programmes in European countries. | ALTEX 20080101 |
Hypokalemic Periodic Paralysis: a case report and review of the literature. | Cases journal 20080101 |
Drug therapy for chronic heart failure due to left ventricular systolic dysfunction. II. Diuretics. | Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20080101 |
Improving the reporting of pragmatic trials: an extension of the CONSORT statement. | BMJ (Clinical research ed.) 20080101 |
Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis. | Arthritis research & therapy 20080101 |
The effects of spironolactone on nephron function in patients with diabetic nephropathy. | Renal failure 20080101 |
[Cardiorenal syndrome]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20080101 |
Implementation of seven echocardiographic parameters of myocardial asynchrony to improve the long-term response rate of cardiac resynchronization therapy (CRT). | Cardiovascular ultrasound 20080101 |
Blockade of renin-angiotensin-aldosterone system in kidney and heart disease: how much do we need? | Acta medica Indonesiana 20080101 |
Ventricular fibrillation triggered by marijuana use in a patient with ischemic cardiomyopathy: a case report. | Cases journal 20080101 |
Spironolactone effective hypertension in the elderly due to 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) impairment: contributory role of determining serum cortisol/cortisone ratio as a marker of 11beta-HSD2 activity. | Internal medicine (Tokyo, Japan) 20080101 |
Septic rupture of the ascending aorta after aortocoronary bypass surgery. | Journal of cardiothoracic surgery 20080101 |
Representational similarity analysis - connecting the branches of systems neuroscience. | Frontiers in systems neuroscience 20080101 |
Food for thought ... On food safety testing. | ALTEX 20080101 |
[Dignity or integrity - does the genetic modification of animals require new concepts in animal ethics?]. | ALTEX 20080101 |
[The metaphysical dimension of animal ethics]. | ALTEX 20080101 |
[Against the pariah's moral. Shopenhauer on the ethics of vivisection]. | ALTEX 20080101 |
Abstracts of the 15th Congress on Alternatives to Animal Experimentation, Linz, Austria, 2008. | ALTEX 20080101 |
Pharmacological profile of progestins. | Maturitas 20080101 |
Classification and pharmacology of progestins. | Maturitas 20080101 |
A case of acute paraplegia that improved with dialysis. | Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 20080101 |
A shift of a fundamental paradigm in toxicology. | ALTEX 20080101 |
Validated HPTLC Method for Simultaneous Determination of Quinapril Hydrochloride and Hydrochlorothiazide in a Tablet Dosage Form. | Indian journal of pharmaceutical sciences 20080101 |
[Aspects of practical diagnosis in perinatal post-hypoxic cardiomiopathy]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101 |
Long QT syndrome: A therapeutic challenge. | Annals of pediatric cardiology 20080101 |
Revised guidelines for management of steroid-sensitive nephrotic syndrome. | Indian journal of nephrology 20080101 |
Spontaneous Bacterial Peritonitis Caused by Infection with Listeria monocytogenes. | Case reports in gastroenterology 20080101 |
In-one-continuity rectal excision and anal mucosectomy of a giant villous adenoma: an alternative surgical approach. | Case reports in gastroenterology 20080101 |
Transcatheter closure of symptomatic aortopulmonary window in an infant. | Images in paediatric cardiology 20080101 |
(S)-N-{3-[1-cyclopropyl-1-(2,4-difluoro-phenyl)-ethyl]-1H-indol-7-yl}-methanesulfonamide: a potent, nonsteroidal, functional antagonist of the mineralocorticoid receptor. | Journal of medicinal chemistry 20071227 |
Decompensated porto-pulmonary hypertension in a cirrhotic patient with thrombosis of portocaval shunt. | World journal of gastroenterology 20071221 |
Mechanisms of progression of chronic kidney disease. | Pediatric nephrology (Berlin, Germany) 20071201 |
Cross-talk between aldosterone and angiotensin II in vascular smooth muscle cell senescence. | Cardiovascular research 20071201 |
Eplerenone relieves spironolactone-induced painful gynaecomastia in patients with decompensated hepatitis B-related cirrhosis. | Scandinavian journal of gastroenterology 20071201 |
Effect of long-term monotherapy with the aldosterone receptor blocker eplerenone on cytoskeletal proteins and matrix metalloproteinases in dogs with heart failure. | Cardiovascular drugs and therapy 20071201 |
Transient prehypertensive treatment in spontaneously hypertensive rats: a comparison of spironolactone and losartan regarding long-term blood pressure and target organ damage. | Journal of hypertension 20071201 |
Amiloride 10 mg is less effective than spironolactone 25 mg in patients with hypertension resistant to a multidrug regime including an angiotensin-blocking agent. | Journal of hypertension 20071201 |
Effects of therapeutic agents on the inflammatory and fibrogenic factors in IgA nephropathy. | Nephrology (Carlton, Vic.) 20071201 |
Evaluation of the aldosterone-blocking agent eplerenone in hypertension and heart failure. | Expert opinion on pharmacotherapy 20071201 |
Additive effects of spironolactone and candesartan on cardiac sympathetic nerve activity and left ventricular remodeling in patients with congestive heart failure. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20071201 |
Is the gap between guidelines and clinical practice in heart failure treatment being filled? Insights from the IMPACT RECO survey. | European journal of heart failure 20071201 |
Patient complexity: more than comorbidity. the vector model of complexity. | Journal of general internal medicine 20071201 |
Aldosterone breakthrough during angiotensin II receptor blockade in hypertensive patients with diabetes mellitus. | American journal of hypertension 20071201 |
Combining neuroendocrine inhibitors in heart failure: reflections on safety and efficacy. | The American journal of medicine 20071201 |
Good blood pressure control on antihypertensives, not only response to spironolactone, predicts improved outcome after adrenalectomy for aldosteronoma. | Surgery 20071201 |
Effects of spironolactone on glucose transport and interleukin-6 secretion in adipose cells of women. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20071201 |
Ectopic ACTH syndrome associated with large-cell neuroendocrine carcinoma of the lung. | The American journal of the medical sciences 20071201 |
The genotype and clinical phenotype of Korean patients with familial hypokalemic periodic paralysis. | Journal of Korean medical science 20071201 |
Optimizing care of heart failure after acute MI with an aldosterone receptor antagonist. | Current heart failure reports 20071201 |
[Pathophysiology of heart failure and the biomarkers; brain natriuretic hormone as the class-1 recommendation by the new Japanese Guideline for Heart Failure]. | Rinsho byori. The Japanese journal of clinical pathology 20071201 |
Spironolactone effects on myocardium changes induced by thyroid hormone in rats. | Arquivos brasileiros de cardiologia 20071201 |
Correlation between NT-proBNP values and changes in functional capacity in patients with chronic heart failure. | Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20071201 |
Central mineralocorticoid receptors are indispensable for corticosterone-induced impairment of memory retrieval in rats. | Neuroscience 20071123 |
Aldosterone-induced coronary dysfunction in transgenic mice involves the calcium-activated potassium (BKCa) channels of vascular smooth muscle cells. | Circulation 20071120 |
Incidence and predictors of hyperkalemia in patients with heart failure: an analysis of the CHARM Program. | Journal of the American College of Cardiology 20071113 |
Aldosterone induces CTGF in mesangial cells by activation of the glucocorticoid receptor. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071101 |
Aldosterone modulates I(f) current through gene expression in cultured neonatal rat ventricular myocytes. | American journal of physiology. Heart and circulatory physiology 20071101 |
Beneficial effect of spironolactone administration on ethynylestradiol-induced cholestasis in the rat: involvement of up-regulation of multidrug resistance-associated protein 2. | Drug metabolism and disposition: the biological fate of chemicals 20071101 |
Aldosterone receptor antagonism alleviates proteinuria, but not malignant hypertension, in Cyp1a1-Ren2 transgenic rats. | American journal of physiology. Renal physiology 20071101 |
Unexpected therapeutic response to spironolactone: a prospective debate on aldosterone and potassium ion in hypertension. | Hypertension (Dallas, Tex. : 1979) 20071101 |
Mineralocorticoid receptor blockade improves vasomotor dysfunction and vascular oxidative stress early after myocardial infarction. | Hypertension (Dallas, Tex. : 1979) 20071101 |
Avoiding vicious circles: mineralocorticoid receptor antagonism prevents vascular oxidative stress early after myocardial infarction. | Hypertension (Dallas, Tex. : 1979) 20071101 |
Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress. | Hypertension (Dallas, Tex. : 1979) 20071101 |
Long-term cardiac effects of adrenalectomy or mineralocorticoid antagonists in patients with primary aldosteronism. | Hypertension (Dallas, Tex. : 1979) 20071101 |
Will the lessons from primary aldosteronism change the treatment of hypertension and left ventricular hypertrophy? | Hypertension (Dallas, Tex. : 1979) 20071101 |
Is aldosterone a pro-arrhythmic hormone? | Journal of hypertension 20071101 |
Spironolactone has antiarrhythmic activity in ischaemic cardiac patients without cardiac failure. | Journal of hypertension 20071101 |
Addition of aldosterone receptor blocker to dual renin-angiotensin-aldosterone blockade leads to limitation of tubulointerstitial injury of kidney. | Kidney international 20071101 |
Influence of combined angiotensin-converting enzyme inhibitors and spironolactone on serum K+, Mg 2+, and Na+ concentrations in small dogs with degenerative mitral valve disease. | Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology 20071101 |
Primary aldosteronism. | Current cardiology reports 20071101 |
Effect of spironolactone on diuresis and urine sodium and potassium excretion in healthy dogs. | Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology 20071101 |
Echocardiographic monitoring of patients with heart failure. | Bosnian journal of basic medical sciences 20071101 |
An electronic strategy to identify hospitalized heart failure patients. | Journal of hospital medicine 20071101 |
Resistant hypertension and aldosteronism. | Current hypertension reports 20071101 |
Translating guidelines into clinical practice: benefits of an acute heart failure unit . | Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20071101 |
Aldosterone causes vasoconstriction in coronary arterioles of rats via angiotensin II type-1 receptor: influence of hypertension. | European journal of pharmacology 20071031 |
Peripartum cardiomyopathy: review of the literature. | Yonsei medical journal 20071031 |
[Drug-induced pseudoaldosteronism]. | Nihon rinsho. Japanese journal of clinical medicine 20071028 |
[Hirsutism]. | Nederlands tijdschrift voor geneeskunde 20071020 |
Zinc dyshomeostasis in rats with aldosteronism. Response to spironolactone. | American journal of physiology. Heart and circulatory physiology 20071001 |
Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport. | Drug metabolism and disposition: the biological fate of chemicals 20071001 |
Does glucocorticoid receptor blockade exacerbate tissue damage after mineralocorticoid/salt administration? | Endocrinology 20071001 |
Intact female stroke-prone hypertensive rats lack responsiveness to mineralocorticoid receptor antagonists. | American journal of physiology. Regulatory, integrative and comparative physiology 20071001 |
Sympathetic hyperactivity and cardiac dysfunction post-MI: different impact of specific CNS versus general AT1 receptor blockade. | Journal of molecular and cellular cardiology 20071001 |
A possible association between primary aldosteronism and a lower beta-cell function. | Journal of hypertension 20071001 |
Effects of aldosterone and angiotensin II receptor blockade on cardiac angiotensinogen and angiotensin-converting enzyme 2 expression in Dahl salt-sensitive hypertensive rats. | American journal of hypertension 20071001 |
Heart failure-complicating acute myocardial infarction. | Heart failure clinics 20071001 |
Stents in the successful management of protein-losing enteropathy after fontan. | The Journal of invasive cardiology 20071001 |
Maximizing diuretic therapy in resistant hypertension. | Journal of clinical hypertension (Greenwich, Conn.) 20071001 |
Lessons in the diagnosis and management of Conn's syndrome. | Clinical medicine (London, England) 20071001 |
Aldosterone antagonism in heart failure. | Vascular health and risk management 20071001 |
Nebivolol in the treatment of chronic heart failure. | Vascular health and risk management 20071001 |
Macro- and micronutrients in patients with congestive heart failure, particularly African-Americans. | Vascular health and risk management 20071001 |
Pharmacological causes of hyperprolactinemia. | Therapeutics and clinical risk management 20071001 |
Pulmonary haemosiderosis with juvenile idiopathic arthritis in a Malaysian child. | The Medical journal of Malaysia 20071001 |
[Effect of aldosterone on the expression of plasminogen activator inhibitor-1 in renal mesangial cells: experiment with rat renal mesangial cells]. | Zhonghua yi xue za zhi 20070911 |
Determination of tumour hypoxia with the PET tracer [18F]EF3: improvement of the tumour-to-background ratio in a mouse tumour model. | European journal of nuclear medicine and molecular imaging 20070901 |
Structural basis of spirolactone recognition by the mineralocorticoid receptor. | Molecular pharmacology 20070901 |
Spironolactone in resistant hypertension. | Hypertension (Dallas, Tex. : 1979) 20070901 |
Aldosterone induces elastin production in cardiac fibroblasts through activation of insulin-like growth factor-I receptors in a mineralocorticoid receptor-independent manner. | The American journal of pathology 20070901 |
[Role of aldosterone in oxidative stress and renal injury]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070901 |
[Molecular mechanism of cardiovascular damage induced by aldosterone]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070901 |
Acute aldosterone infusion enhances thrombosis development in normotensive rats. | Thrombosis and haemostasis 20070901 |
Potent diuretic effects of prednisone in heart failure patients with refractory diuretic resistance. | The Canadian journal of cardiology 20070901 |
Beneficial effects of spironolactone on glomerular injury in streptozotocin-induced diabetic rats. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20070901 |
Combination therapy with telmisartan and spironolactone alleviates L-NAME exacerbated nephrosclerosis with an increase in PPAR-gamma and decrease in TGF-beta(1). | International heart journal 20070901 |
Prehypertensive renin-angiotensin-aldosterone system blockade in spontaneously hypertensive rats ameliorates the loss of long-term vascular function. | Hypertension research : official journal of the Japanese Society of Hypertension 20070901 |
Worsening of motor symptoms and gynecomastia during spironolactone treatment in a patient with Parkinson's disease and congestive heart failure. | Movement disorders : official journal of the Movement Disorder Society 20070815 |
Persistent use of evidence-based pharmacotherapy in heart failure is associated with improved outcomes. | Circulation 20070814 |
Aldosterone receptor antagonism induces reverse remodeling when added to angiotensin receptor blockade in chronic heart failure. | Journal of the American College of Cardiology 20070814 |
Brain mechanisms contributing to sympathetic hyperactivity and heart failure. | Circulation research 20070803 |
Mineralocorticoid receptor blockade attenuates chronic overexpression of the renin-angiotensin-aldosterone system stimulation of reduced nicotinamide adenine dinucleotide phosphate oxidase and cardiac remodeling. | Endocrinology 20070801 |
Estrogen receptor activation--good, aldosterone receptor blockade--beneficial, communication between receptors...priceless. | Hypertension (Dallas, Tex. : 1979) 20070801 |
Polycystic ovary syndrome: implications of corticotropin in the regulation of blood pressure, aldosterone, and androgen secretion. | Hypertension (Dallas, Tex. : 1979) 20070801 |
Cortisol regulation of ion transporter mRNA in Atlantic salmon gill and the effect of salinity on the signaling pathway. | The Journal of endocrinology 20070801 |
Construction of 3D models of the CYP11B family as a tool to predict ligand binding characteristics. | Journal of computer-aided molecular design 20070801 |
How evidence-based are the recommendations in evidence-based guidelines? | PLoS medicine 20070801 |
Spironolactone use in resistant hypertension. | Current hypertension reports 20070801 |
Diuretics in obstructive sleep apnea with diastolic heart failure. | Chest 20070801 |
Solid dispersion of spironolactone with porous silica prepared by the solvent method. | Die Pharmazie 20070801 |
[Individualization of low-dose oral contraceptives. Pharmacological principles and practical indications for oral contraceptives]. | Minerva ginecologica 20070801 |
Bisoprolol in the treatment of chronic heart failure. | Vascular health and risk management 20070801 |
Treatment of premenstrual dysphoric disorder (PMDD) with a novel formulation of drospirenone and ethinyl estradiol. | Therapeutics and clinical risk management 20070801 |
[The effect of angiotensin-converting enzyme inhibitors and aldosterone receptor blockers on cardiac function in calcium-overload rats]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070801 |
Aldosterone upregulates vascular endothelial growth factor expression in mouse cortical collecting duct epithelial cells through classic mineralocorticoid receptor. | Life sciences 20070726 |
Involvement of the lateral septum and the ventral Hippocampus in the emotional sequelae induced by social defeat: role of glucocorticoid receptors. | Behavioural brain research 20070719 |
The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio. | Circulation 20070717 |
Usefulness of the aldosterone synthase gene polymorphism C-344-T to predict cardiac remodeling in African-Americans versus non-African-Americans with chronic systolic heart failure. | The American journal of cardiology 20070715 |
The 6-minute walk test predicts clinical outcome in Asian patients with chronic congestive heart failure on contemporary medical therapy: a study of the multiracial population in Singapore. | International journal of cardiology 20070710 |
[Increased risk of gastrointestinal bleeding or ulcers when using spironolactone: a case-control study]. | Nederlands tijdschrift voor geneeskunde 20070707 |
Pretreatment with eplerenone reduces stroke volume in mouse middle cerebral artery occlusion model. | European journal of pharmacology 20070702 |
Added value of a physician-and-nurse-directed heart failure clinic: results from the Deventer-Alkmaar heart failure study. | Heart (British Cardiac Society) 20070701 |
Renal ischemia-reperfusion injury is prevented by the mineralocorticoid receptor blocker spironolactone. | American journal of physiology. Renal physiology 20070701 |
Pivotal role of the mineralocorticoid receptor in corticosteroid-induced adipogenesis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701 |
Evaluation of effects of an oral contraceptive containing ethinylestradiol combined with drospirenone on adrenal steroidogenesis in hyperandrogenic women with polycystic ovary syndrome. | Fertility and sterility 20070701 |
New insights into the pathophysiology of cyclosporine nephrotoxicity: a role of aldosterone. | American journal of physiology. Renal physiology 20070701 |
Beneficial effects of eplerenone versus hydrochlorothiazide on coronary circulatory function in patients with diabetes mellitus. | The Journal of clinical endocrinology and metabolism 20070701 |
Renal cysts and hypokalemia in primary aldosteronism: results of long-term follow-up after treatment. | Journal of hypertension 20070701 |
Curriculum in cardiology: Integrated diagnosis and management of diastolic heart failure (Am Heart J 2007;153:189-200). | American heart journal 20070701 |
Drug insight: aldosterone-receptor antagonists in heart failure--the journey continues. | Nature clinical practice. Cardiovascular medicine 20070701 |
Aldosterone induces circadian gene expression of clock genes in H9c2 cardiomyoblasts. | Heart and vessels 20070701 |
Spironolactone found effective for patients with resistant hypertension in ASCTT-BPLA. | Journal of clinical hypertension (Greenwich, Conn.) 20070701 |
Tailored hormonal therapy in secretory adrenocortical cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20070701 |
[A 87-year-old woman with mineralocorticoid excess due to 11 beta-HSD2 deficiency]. | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20070701 |
Combination of drospirenone and estradiol: a new hormone therapy in postmenopausal women. | Women's health (London, England) 20070701 |
Spirolactone iridoids might be responsible for the antileishmanial activity of a Peruvian traditional remedy made with Himatanthus sucuuba (Apocynaceae). | Journal of ethnopharmacology 20070613 |
Treatment practices in heart failure with preserved left ventricular ejection fraction: a prospective observational study. | International journal of cardiology 20070612 |
Aldosterone-induced EGFR expression: interaction between the human mineralocorticoid receptor and the human EGFR promoter. | American journal of physiology. Endocrinology and metabolism 20070601 |
Corticosteroid receptor-mediated mechanisms in the amygdala regulate anxiety and colonic sensitivity. | American journal of physiology. Gastrointestinal and liver physiology 20070601 |
Transcriptional regulation of intronic calcium-activated potassium channel SK2 promoters by nuclear factor-kappa B and glucocorticoids. | Molecular and cellular biochemistry 20070601 |
Stereoselective synthesis of the two major metabolites of spironolactone, 3alpha- and 3beta-hydroxy-7alpha-methylthio-17alpha-pregn-4-ene-21,17-carbolactone. | Steroids 20070601 |
Delayed recovery of left ventricular systolic dysfunction: ''give time to medical therapy''. | Minerva cardioangiologica 20070601 |
Association of beta-blocker dose with serum procollagen concentrations and cardiac response to spironolactone in patients with heart failure. | Pharmacotherapy 20070601 |
Does heart failure therapy differ according to patient sex? | Clinical cardiology 20070601 |
Life-threatening Pneumocystis jiroveci pneumonia following treatment of severe Cushing's syndrome. | The Netherlands journal of medicine 20070601 |
Mesangial proliferative glomerulonephritis with aldosterone-producing adenoma. | Clinical and experimental nephrology 20070601 |
Cushing's syndrome patient who exhibited congestive heart failure. | Journal of endocrinological investigation 20070601 |
Mechanisms and treatment of resistant hypertension. | Arquivos brasileiros de cardiologia 20070601 |
Female pattern hair loss: current treatment concepts. | Clinical interventions in aging 20070601 |
Letter by Pascual-Figal et al regarding article, 'Anabolic deficiency in men with chronic heart failure: prevalence and detrimental impact on survival'. | Circulation 20070529 |
[Spironolactone as a cardio-protective drug]. | Nihon rinsho. Japanese journal of clinical medicine 20070528 |
[Eplerenone for treatment of heart failure]. | Nihon rinsho. Japanese journal of clinical medicine 20070528 |
[Aldosterone antagonists: characteristics, mechanisms of action, pharmacokinetics, indication, contraindication, clinical data, and side effects]. | Nihon rinsho. Japanese journal of clinical medicine 20070528 |
Stereoselective total synthesis of (+)-Scyphostatin via a pi-facially selective Diels-Alder reaction. | The Journal of organic chemistry 20070525 |
Involvement of noradrenergic and corticoid receptors in the consolidation of the lasting anxiogenic effects of predator stress. | Behavioural brain research 20070516 |
Antagonistic effects of bone morphogenetic protein-4 and -7 on renal mesangial cell proliferation induced by aldosterone through MAPK activation. | American journal of physiology. Renal physiology 20070501 |
Spironolactone improves structure and increases tone in the cerebral vasculature of male spontaneously hypertensive stroke-prone rats. | Microvascular research 20070501 |
Glucocorticoids stimulate ENaC upregulation in bovine mammary epithelium. | American journal of physiology. Cell physiology 20070501 |
Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501 |
Treatment of diuretic refractory pleural effusions with bevacizumab in four patients with primary systemic amyloidosis. | American journal of hematology 20070501 |
Drospirenone: a novel progestin. | Expert opinion on pharmacotherapy 20070501 |
68-year-old woman with hepatitis C and abnormal kidney function. | Mayo Clinic proceedings 20070501 |
Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation. | Journal of cardiovascular pharmacology 20070501 |
Spironolactone modulates expressions of cardiac mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase 2 and prevents ventricular remodeling in post-infarct rat hearts. | Hypertension research : official journal of the Japanese Society of Hypertension 20070501 |
[Effects of aldosterone on inducible nitric oxide synthase/nitric oxide pathway in aortic adventitia]. | Zhonghua xin xue guan bing za zhi 20070501 |
Premenstrual syndrome. | BMJ clinical evidence 20070501 |
[Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study]. | Nihon rinsho. Japanese journal of clinical medicine 20070428 |
Effect of spironolactone on C-reactive protein levels in patients with heart disease. | International journal of cardiology 20070425 |
Primary percutaneous coronary intervention. | The New England journal of medicine 20070412 |
[Treatment for symptoms of pseudoaldosteronism]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070410 |
Complementary and incremental mortality risk prediction by cortisol and aldosterone in chronic heart failure. | Circulation 20070403 |
Effects of aldosterone receptor blockade in patients with mild-moderate heart failure taking a beta-blocker. | European journal of heart failure 20070401 |
Transactivation of the IGF-1R by aldosterone. | American journal of physiology. Renal physiology 20070401 |
Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system. | Endocrinology 20070401 |
Mineralocorticoid receptor activation promotes vascular cell calcification. | Arteriosclerosis, thrombosis, and vascular biology 20070401 |
A German family with glucocorticoid-remediable aldosteronism. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070401 |
Treatment of heart failure with ACE inhibitors and beta-blockers: what is next? Aldosterone receptor antagonists? | Clinical research in cardiology : official journal of the German Cardiac Society 20070401 |
Treating resistant hypertension with a neglected old drug. | Hypertension (Dallas, Tex. : 1979) 20070401 |
Effect of spironolactone on blood pressure in subjects with resistant hypertension. | Hypertension (Dallas, Tex. : 1979) 20070401 |
Aldosterone antagonist therapy in resistant hypertension. | Journal of hypertension 20070401 |
Low-dose spironolactone in the management of resistant hypertension: a surveillance study. | Journal of hypertension 20070401 |
Current guidelines for treatment of heart failure: 2006 update. | Pharmacotherapy 20070401 |
A randomized trial of carvedilol after renin-angiotensin system inhibition in chronic Chagas cardiomyopathy. | American heart journal 20070401 |
Specific activation of the glucocorticoid receptor and modulation of signal transduction pathways in human lens epithelial cells. | Investigative ophthalmology & visual science 20070401 |
The effect of spironolactone use on heart failure mortality: a population-based study. | Journal of cardiac failure 20070401 |
Spironolactone reduced arrhythmia and maintained magnesium homeostasis in patients with congestive heart failure. | Journal of cardiac failure 20070401 |
Aldosterone antagonism fails to attenuate age-associated left ventricular fibrosis. | The journals of gerontology. Series A, Biological sciences and medical sciences 20070401 |
Impact of a specialized outpatient heart failure follow-up program on hospitalization frequency and functional status of patients with advanced heart failure. | Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20070401 |
Aldosterone up-regulates production of plasminogen activator inhibitor-1 by renal mesangial cells. | Journal of biochemistry and molecular biology 20070331 |
Nonpharmacologic measures and drug compliance in patients with heart failure: data from the EuroHeart Failure Survey. | The American journal of cardiology 20070326 |
International variations in the treatment and co-morbidity of left ventricular systolic dysfunction: data from the EuroHeart Failure Survey. | European journal of heart failure 20070301 |
Sleep-disordered breathing in patients with symptomatic heart failure: a contemporary study of prevalence in and characteristics of 700 patients. | European journal of heart failure 20070301 |
Treatment of polycystic ovary syndrome with spironolactone plus licorice. | European journal of obstetrics, gynecology, and reproductive biology 20070301 |
Primary hyperaldosteronism in a patient with end-stage renal disease. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070301 |
Reactive oxygen species-dependent hypertension in dopamine D2 receptor-deficient mice. | Hypertension (Dallas, Tex. : 1979) 20070301 |
Increased cyclooxygenase-2 expression in hypothalamic paraventricular nucleus in rats with heart failure: role of nuclear factor kappaB. | Hypertension (Dallas, Tex. : 1979) 20070301 |
Interactions between aldosterone and connective tissue growth factor in vascular and renal damage in spontaneously hypertensive rats. | Journal of hypertension 20070301 |
Dose-dependent endothelial cell growth and stiffening by aldosterone: endothelial protection by eplerenone. | Journal of hypertension 20070301 |
Primary aldosteronism: current knowledge and controversies in Conn's syndrome. | Nature clinical practice. Endocrinology & metabolism 20070301 |
Effects of medical therapy on insulin resistance and the cardiovascular system in polycystic ovary syndrome. | Diabetes care 20070301 |
A Caenorhabditis elegans wild type defies the temperature-size rule owing to a single nucleotide polymorphism in tra-3. | PLoS genetics 20070301 |
Standard therapies for pulmonary arterial hypertension. | Clinics in chest medicine 20070301 |
Mineralocorticoid receptor antagonists. | Current hypertension reports 20070301 |
[Anaesthesia for patients with adrenal gland diseases]. | Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20070301 |
Hypokalemia secondary to capecitabine: a hidden toxicity? | Therapeutics and clinical risk management 20070301 |
Spironolactone-induced gynecomastia. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070227 |
Rapid effects of aldosterone on clonal human vascular smooth muscle cells. | American journal of physiology. Cell physiology 20070201 |
Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure: Beneficial effects of mineralocorticoid receptor blocker. | American journal of physiology. Regulatory, integrative and comparative physiology 20070201 |
Role of glucocorticoid receptor in acclimation of killifish (Fundulus heteroclitus) to seawater and effects of arsenic. | American journal of physiology. Regulatory, integrative and comparative physiology 20070201 |
Heart-failure-complicating acute myocardial infarction. | Clinics in geriatric medicine 20070201 |
Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1. | Hypertension (Dallas, Tex. : 1979) 20070201 |
Treatment of female pattern hair loss with a combination of spironolactone and minoxidil. | The Australasian journal of dermatology 20070201 |
Serum potassium monitoring for users of ethinyl estradiol/drospirenone taking medications predisposing to hyperkalemia: physician compliance and survey of knowledge and attitudes. | Contraception 20070201 |
Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity. | Nature medicine 20070201 |
Laboratory evaluation of potassium and creatinine among ambulatory patients prescribed spironolactone: are we monitoring for hyperkalemia? | The Annals of pharmacotherapy 20070201 |
[Effects of aldosterone on synthesis of fibronectin and expression of transforming growth factor-beta1 mRNA in cultured rat mesangial cells]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20070201 |
Drug-induced hyperkalaemia is frequent. | Prescrire international 20070201 |
Sexual hormones in human skin. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20070201 |
[Portopulmonary hypertension due to schistosomiasis in two Malagasy patients]. | Bulletin de la Societe de pathologie exotique (1990) 20070201 |
Non-genomic effects of aldosterone on intracellular ion regulation and cell volume in rat ventricular myocytes. | Canadian journal of physiology and pharmacology 20070201 |
Modulating the development of renal tubules growing in serum-free culture medium at an artificial interstitium. | Tissue engineering 20070201 |
Effect of lipid-lowering and anti-hypertensive drugs on plasma homocysteine levels. | Vascular health and risk management 20070201 |
Eplerenone suppresses neointima after coronary stenting in pigs: could it be extrapolated to stent restenosis in humans? | International journal of cardiology 20070131 |
The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay. | Biochemistry 20070123 |
Eplerenone offsets cardiac and aortic adverse remodeling in spontaneously hypertensive rats. | International journal of cardiology 20070102 |
Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity. | American journal of physiology. Renal physiology 20070101 |
Long-term mineralocorticoid receptor blockade reduces fibrosis and improves cardiac performance and coronary hemodynamics in elderly SHR. | American journal of physiology. Heart and circulatory physiology 20070101 |
Maintained ENaC trafficking in aldosterone-infused rats during mineralocorticoid and glucocorticoid receptor blockade. | American journal of physiology. Renal physiology 20070101 |
Is primary hyperaldosteronism a risk factor for aortic dissection? | Cardiology 20070101 |
In silico prediction of pregnane X receptor activators by machine learning approaches. | Molecular pharmacology 20070101 |
Eplerenone relieves spironolactone-induced painful gynaecomastia in a patient with primary aldosteronism. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070101 |
Blockade of the mineralocorticoid receptor in healthy men: effects on experimentally induced panic symptoms, stress hormones, and cognition. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070101 |
Modelling the human epidermis in vitro: tools for basic and applied research. | Archives of dermatological research 20070101 |
Therapeutic approach to FSGS in children. | Pediatric nephrology (Berlin, Germany) 20070101 |
Incidence and predictors of development of acute renal failure related to treatment of congestive heart failure with ACE inhibitors. | Nephron. Clinical practice 20070101 |
Spironolactone might be a desirable immunologic and hormonal intervention in autism spectrum disorders. | Medical hypotheses 20070101 |
Migraine with aura following atrial septostomy for pulmonary arterial hypertension. | Nature clinical practice. Cardiovascular medicine 20070101 |
Valsartan treatment reverses erectile dysfunction in diabetic rats. | International journal of impotence research 20070101 |
Randomized, placebo-controlled trial of the effects of drospirenone-estradiol on blood pressure and potassium balance in hypertensive postmenopausal women receiving hydrochlorothiazide. | Menopause (New York, N.Y.) 20070101 |
Historical trends in survival of hospitalized heart failure patients: 2000 versus 1995. | BMC cardiovascular disorders 20070101 |
Effects of urodilatin on natriuresis in cirrhosis patients with sodium retention. | BMC gastroenterology 20070101 |
Methods for dealing with discrepant records in linked population health datasets: a cross-sectional study. | BMC health services research 20070101 |
[Anesthetic management for mediastinoscopy in a patient with severe pulmonary hypertension]. | Revista espanola de anestesiologia y reanimacion 20070101 |
[Influence of diuretics on occupationally important qualities of engine drivers]. | Meditsina truda i promyshlennaia ekologiia 20070101 |
Aldosterone antagonists: the most underutilized class of heart failure medications. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101 |
The embryonic stem cell test for the early selection of pharmaceutical compounds. | ALTEX 20070101 |
Neuronal cell culture from human embryonic stem cells as in vitro model for neuroprotection. | ALTEX 20070101 |
Cell culture model for colon cancer prevention and therapy: an alternative approach to animal experimentation. | ALTEX 20070101 |
In vitro system for the prediction of hepatotoxic effects in primary hepatocytes. | ALTEX 20070101 |
Use of a standardised and validated long-term human hepatocyte culture system for repetitive analyses of drugs: repeated administrations of acetaminophen reduces albumin and urea secretion. | ALTEX 20070101 |
[Revision of the EU Directive 86/609/EEC: results of the Internet consultations of the European Commission]. | ALTEX 20070101 |
[Prospective observational study of drug-induced hyperkalemia in hospitalized non dialized adult patients]. | Therapie 20070101 |
Update of diuretics in the treatment of hypertension. | American journal of therapeutics 20070101 |
Development of a decision support tool to facilitate primary care management of patients with abnormal liver function tests without clinically apparent liver disease [HTA03/38/02]. Abnormal Liver Function Investigations Evaluation (ALFIE). | BMC health services research 20070101 |
A flow-injection chemiluminescence method for the determination of human serum albumin, using the reaction of fluorescein-human serum albumin-sodium hypochlorite by the enhancement effect of the cationic surfactant cetyltrimethylammonium bromide. | Luminescence : the journal of biological and chemical luminescence 20070101 |
Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. | Internal medicine (Tokyo, Japan) 20070101 |
Association of androgenetic alopecia and hypertension. | European journal of dermatology : EJD 20070101 |
Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study. | BMC cardiovascular disorders 20070101 |
Application of vacuum-assisted therapy in postoperative ascitic fluid leaks: an integral part of multimodality wound management in cirrhotic patients. | Journal of burns and wounds 20070101 |
Circadian blood pressure variation and antihypertensive medication adjustment in normoalbuminuric type 2 diabetes patients. | Kidney & blood pressure research 20070101 |
[Laryngoplasty with cutaneous tube--methods of surgical treatment in caustic stenosis]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20070101 |
The effects of irbesartan and spironolactone in prevention of peritoneal fibrosis in rats. | Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20070101 |
Aldosterone receptor antagonists induce favorable cardiac remodeling in diastolic heart failure patients. | Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20070101 |
Process evaluation for complex interventions in primary care: understanding trials using the normalization process model. | BMC family practice 20070101 |
Metabolic syndrome: treatment of hypertensive patients. | American journal of therapeutics 20070101 |
Aldosterone rapidly activates protein kinase D via a mineralocorticoid receptor/EGFR trans-activation pathway in the M1 kidney CCD cell line. | The Journal of steroid biochemistry and molecular biology 20070101 |
[Abdominal tuberculosis--a surgical reality]. | Chirurgia (Bucharest, Romania : 1990) 20070101 |
Treatment of cirrhotic ascites. | Acta gastro-enterologica Belgica 20070101 |
Thiazolidinediones and their fluid-related adverse effects: facts, fiction and putative management strategies. | Drug safety 20070101 |
Safety testing of cell-based medicinal products: opportunities for the monocyte activation test for pyrogens. | ALTEX 20070101 |
The effectiveness of humane teaching methods in veterinary education. | ALTEX 20070101 |
Serum-free culturing of mammalian cells--adaptation to and cryopreservation in fully defined media. | ALTEX 20070101 |
Alternatives in pharmaceutical toxicology: global and focussed approaches--two case studies. | ALTEX 20070101 |
Spontaneous, L-arginine-induced and spironolactone-induced regression of protein remodeling of the left ventricle in L-NAME-induced hypertension. | Physiological research 20070101 |
Comparison of the effect of simvastatin, spironolactone and L-arginine on endothelial function of aorta in hereditary hypertriglyceridemic rats. | Physiological research 20070101 |
Spironolactone differently influences remodeling of the left ventricle and aorta in L-NAME-induced hypertension. | Physiological research 20070101 |
Food for thought ... on validation. | ALTEX 20070101 |
VirtualToxLab - in silico prediction of the toxic potential of drugs and environmental chemicals: evaluation status and internet access protocol. | ALTEX 20070101 |
Movement to curtail animal dissections in zoology curriculum: review of the Indian experience. | ALTEX 20070101 |
SkinEthic Laboratories, a company devoted to develop and produce in vitro alternative methods to animal use. | ALTEX 20070101 |
Role of simulators in surgical education. | ALTEX 20070101 |
Relevance of in vitro toxicology studies in risk assessment. | ALTEX 20070101 |
Updated meta-analytical approach to the efficacy of antihypertensive drugs in reducing blood pressure. | Clinical drug investigation 20070101 |
Food for thought... on cell culture. | ALTEX 20070101 |
[Pancreaticoduodenectomy for pancreatic head cancer, 54 cases]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20070101 |
[Radiofrequency ablation in the multimodal treatment of liver metastases--preliminary report]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20070101 |
Pathophysiology of ascites and dilutional hyponatremia: contemporary use of aquaretic agents. | Annals of hepatology 20070101 |
Detection of spironolactone-associated hyperkalaemia following the Randomized Aldactone Evaluation Study (RALES). | Drug safety 20070101 |
Effects of spironolactone on corneal allograft survival in the rat. | Ophthalmic research 20070101 |
Hematochezia in a patient with liver cirrhosis. | World journal of emergency surgery : WJES 20070101 |
[Milestones of cardiovascular therapy. V. Diuretics]. | Casopis lekaru ceskych 20070101 |
The efficacy and safety of amoxicillin, trimethoprim-sulfamethoxazole, and spironolactone for treatment-resistant acne vulgaris. | Advances in dermatology 20070101 |
Posterior mediastinal hematoma - a rare case following a fall from standing height: a case report. | Journal of medical case reports 20070101 |
Probrain natriuretic peptide for assessment of efficacy in heart failure treatment. | Advances in therapy 20070101 |
The mineralocorticoid receptor: insights into its molecular and (patho)physiological biology. | Nuclear receptor signaling 20070101 |
[Efficacy and safety of long-term application of spironolactone in patients with moderate and severe chronic heart failure receiving optimal therapy]. | Kardiologiia 20070101 |
Food for thought ... on globalisation of alternative methods. | ALTEX 20070101 |
Factors stimulating or obstructing the implementation of the 3Rs in the regulatory process. | ALTEX 20070101 |
[The duty of official discretion for members of the animal experiment commission (notably in the Canton Zurich)]. | ALTEX 20070101 |
Animal experiments scrutinised: systematic reviews demonstrate poor human clinical and toxicological utility. | ALTEX 20070101 |
A survey concerning the work of ethics committees and licensing authorities for animal experiments in Germany. | ALTEX 20070101 |
Trial on personhood for chimp 'Hiasl'. | ALTEX 20070101 |
[The characteristics of left ventricular myocardial remodeling in patients with chronic renal disease, and the effects of spironolactone therapy]. | Klinicheskaia meditsina 20070101 |
[Pancreaticoduodenectomy with or without pylorus preservation: a retrospective analysis of 137 patients]. | Chirurgia (Bucharest, Romania : 1990) 20070101 |
[Our experience in primary hyperaldosteronism]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20070101 |
[Cervical metastatic adenopathy from the oropharynx cancer]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20070101 |
[Hospital management--performance measuring models]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20070101 |
[Pathophysiological role of aldosterone in acute renal failure]. | Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20070101 |
Heart failure management in Poland: The National Cardiovascular Disease Prevention and Treatment Program POLKARD, edition 2003-2005. | Cardiology journal 20070101 |
The risks and benefits of therapy with aldosterone receptor antagonist therapy. | Current drug safety 20070101 |
Skin sensitization: understanding the in vivo situation for the development of reliable in vitro test approaches. | ALTEX 20070101 |
Improvement of pain therapy in laboratory mice. | ALTEX 20070101 |
Exploring natural anticoagulation by endothelial cells: a novel in vitro model. | ALTEX 20070101 |
Non-invasive methods: investigation of airways diseases by MRI in rats. | ALTEX 20070101 |
Simulation of stroke-related damage in cultured human nerve cells. | ALTEX 20070101 |
Animalfree screening of biological materials for contamination by rodent viruses. | ALTEX 20070101 |
Identification of neurotoxic chemicals in cell cultures. | ALTEX 20070101 |
Permanent fish cell cultures as important tools in ecotoxicology. | ALTEX 20070101 |
Generation of parasite cysts in cultured cells instead of living animals. | ALTEX 20070101 |
Aggregating brain cell cultures: investigation of stroke related brain damage. | ALTEX 20070101 |
Formation of new blood vessels in the heart can be studied in cell cultures. | ALTEX 20070101 |
The tick blood meal: from a living animal or from a silicone membrane? | ALTEX 20070101 |
Generation and use of a mouse Kupffer cell line. | ALTEX 20070101 |
Welfare assessment and phenotype characterisation of transgenic mice. | ALTEX 20070101 |
Predicting drug hypersensitivity by in vitro tests. | ALTEX 20070101 |
From blood to brain and vice versa: transport processes in choroid plexus can be studied in vitro. | ALTEX 20070101 |
Establishing a 3D ex vivo culture system for investigations of bone metabolism and biomaterial interactions. | ALTEX 20070101 |
Fever in the test tube--towards a human(e) pyrogen test. | ALTEX 20070101 |
Predicting the toxic potential of drugs and chemicals in silico. | ALTEX 20070101 |
Housing and husbandry conditions affect stereotypic behaviour in laboratory gerbils. | ALTEX 20070101 |
Environmental enrichment does not disrupt standardisation of animal experiments. | ALTEX 20070101 |
Isolated, autologous blood-perfused heart: replacement of heterotopic heart transplantation. | ALTEX 20070101 |
Assessment of pain and stress in mice by monitoring gene expression changes. | ALTEX 20070101 |
A non-mammalian system to study bacterial infections. | ALTEX 20070101 |
Development of QSAR-models for classification and prediction of baseline toxicity and of uncoupling of energy transduction. | ALTEX 20070101 |
Development of an in vitro system for modeling bioaccumulation of neutral, ionizable, and metabolically active organic pollutants in fish. | ALTEX 20070101 |
Assessing animal health and welfare and recognising pain and distress. | ALTEX 20070101 |
In vitro replica of the inner surface of the lungs for the study of particle-cell interaction. | ALTEX 20070101 |
Organotypic CNS slice cultures as an in vitro model for immune mediated tissue damage and repair in multiple sclerosis. | ALTEX 20070101 |
Development of in vitro strategies to propagate and characterise hemotrophic mycoplasmas. | ALTEX 20070101 |
The development of an in vitro intervertebral disc organ culture system. | ALTEX 20070101 |
An in vitro model of central nervous system infection and regeneration: neuronal stem cells as targets of brain damage and regenerative therapies in bacterial meningitis. | ALTEX 20070101 |
Development of a three-dimensional enteric cell culture model for in vitro studies of the intestinal eukaryotic parasites Cryptosporidium spp. | ALTEX 20070101 |
Establishment of a murine syngeneic co-culture system of intestinal epithelial cells with intraepithelial T lymphocyte subsets. | ALTEX 20070101 |
Development of a novel multicellular 3-dimensional blood brain barrier in vitro model. | ALTEX 20070101 |
Adjuvanticity of microbial-derived particles and synthetic analogs in vitro. | ALTEX 20070101 |
Establishment of an in vitro system for the prediction of the degree of virulence of classical swine fever virus isolates. | ALTEX 20070101 |
Information on serum free cell lines, an interactive database. | ALTEX 20070101 |
Dilated cardiomyopathy of unknown cause in young patients: risk evaluation, possible etiologies, and treatment. | The Libyan journal of medicine 20070101 |
Angiotensin blockade or aldosterone blockade as the third neuroendocrine-blocking drug in mild but symptomatic heart failure patients. | Heart (British Cardiac Society) 20061201 |
Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease. | Kidney international 20061201 |
The effect of aldosterone blockade in patients with Alport syndrome. | Pediatric nephrology (Berlin, Germany) 20061201 |
Angiotensin II induces interleukin-6 in humans through a mineralocorticoid receptor-dependent mechanism. | Hypertension (Dallas, Tex. : 1979) 20061201 |
Spironolactone induces apoptosis and inhibits NF-kappaB independent of the mineralocorticoid receptor. | Apoptosis : an international journal on programmed cell death 20061201 |
Why are mineralocorticoid receptor antagonists cardioprotective? | Naunyn-Schmiedeberg's archives of pharmacology 20061201 |
Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome: possible contribution of fat-derived factors. | Journal of the American Society of Nephrology : JASN 20061201 |
Effect of various diuretic treatments on rosiglitazone-induced fluid retention. | Journal of the American Society of Nephrology : JASN 20061201 |
Isolated ventricular non-compaction: clinical study and genetic review. | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20061201 |
The effect of spironolactone on circulating adipocytokines in patients with type 2 diabetes mellitus complicated by diabetic nephropathy. | Metabolism: clinical and experimental 20061201 |
Micronutrients in African-Americans with decompensated and compensated heart failure. | Translational research : the journal of laboratory and clinical medicine 20061201 |
The role of BNP testing in heart failure. | American family physician 20061201 |
Dihydroxy-, hydroxyspirolactone-, and dihydroxyspirolactone-urochlorins induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the liver of mice. | Chemical research in toxicology 20061201 |
Direct effects of 3 combinations of enalapril, metoprolol, and spironolactone on cardiac remodeling in dilated cardiomyopathic hamsters. | Journal of cardiac failure 20061201 |
Carvedilol accelerate elevation of serum potassium in chronic heart failure patients administered spironolactone plus furosemide and either enalapril maleate or candesartan cilexetil. | Journal of clinical pharmacy and therapeutics 20061201 |
Combined effects of low-dose spironolactone and captopril therapy in a rat model of genetic hypertrophic cardiomyopathy. | Journal of cardiovascular pharmacology 20061201 |
Adherence to guidelines for patients hospitalized with heart failure: a nationwide survey. | The Israel Medical Association journal : IMAJ 20061201 |
Junctional escape rhythm secondary to acute hyperkalemic renal failure in the setting of concurrent beta-blocker therapy. | JAAPA : official journal of the American Academy of Physician Assistants 20061201 |
High-speed gas chromatography in doping control: fast-GC and fast-GC/MS determination of beta-adrenoceptor ligands and diuretics. | Journal of separation science 20061201 |
Sexual function in hypertensive patients receiving treatment. | Vascular health and risk management 20061201 |
Effect of treatment of rosacea in females by Chibixiao Recipe in combination with minocycline and spironolactone. | Chinese journal of integrative medicine 20061201 |
Candesartan in heart failure. | Clinical interventions in aging 20061201 |
[The role of MAPK/ERK1/2 signaling pathway in aldosterone stimulated transforming growth factor-beta1 synthesis in renal tubular epithelial cells]. | Zhonghua yi xue za zhi 20061128 |
Preparation and characterization of spironolactone-loaded nanocapsules for paediatric use. | International journal of pharmaceutics 20061115 |
Synthetic studies on perophoramidine and the communesins: construction of the vicinal quaternary stereocenters. | The Journal of organic chemistry 20061110 |
[MEN type I presenting hypokalemia and hypertension, complicated with acromegaly, adrenal cortical tumor and rectal carcinoid tumor]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20061110 |
Left ventricular assist device and drug therapy for the reversal of heart failure. | The New England journal of medicine 20061102 |
Aldosterone inhibits apical NHE3 and HCO3- absorption via a nongenomic ERK-dependent pathway in medullary thick ascending limb. | American journal of physiology. Renal physiology 20061101 |
Urea transporter UT-A1 and aquaporin-2 proteins decrease in response to angiotensin II or norepinephrine-induced acute hypertension. | American journal of physiology. Renal physiology 20061101 |
Reports of hyperkalemia after publication of RALES--a pharmacovigilance study. | Pharmacoepidemiology and drug safety 20061101 |
MR blockade in patients with chronic renal disease--not the more the merrier, but the earlier the better. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061101 |
Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus. | Endocrinology 20061101 |
Does eplerenone have a future in the management of hypertension in Europe? | Journal of human hypertension 20061101 |
Use of antagonists of aldosterone in patients with chronic kidney disease: Potential advantages and risks. | Journal of hypertension 20061101 |
Antiangiogenic effects of spironolactone and other potassium-sparing diuretics in human umbilical vein endothelial cells and in fibrin gel chambers implanted in rats. | Journal of hypertension 20061101 |
Spironolactone in type 2 diabetic nephropathy: Effects on proteinuria, blood pressure and renal function. | Journal of hypertension 20061101 |
Effects of mineralocorticoid and glucocorticoid receptor blockade on hypothalamic-pituitary-adrenal function in female rats prenatally exposed to ethanol. | Alcoholism, clinical and experimental research 20061101 |
Aldosterone blockade: an emerging strategy for abrogating progressive renal disease. | The American journal of medicine 20061101 |
Aldosterone synthesis and cytokine production in human peripheral blood mononuclear cells. | Journal of pharmacological sciences 20061101 |
Cushing's syndrome caused by an occult source: difficulties in diagnosis and management. | Nature clinical practice. Endocrinology & metabolism 20061101 |
[Simultaneous determination of inhibitive components in anti-acne cosmetics by reversed-phase high performance liquid chromatography]. | Se pu = Chinese journal of chromatography 20061101 |
Current usage of diuretics among hypertensive patients in Japan: the Japan Home versus Office Blood Pressure Measurement Evaluation (J-HOME) study. | Hypertension research : official journal of the Japanese Society of Hypertension 20061101 |
[Cardioverter-defibrillator (ICD) and resynchronization in every patient with cardiac failure]. | Deutsche medizinische Wochenschrift (1946) 20061013 |
Maternal exposure to estradiol and endocrine disrupting compounds alters the sensitivity of sea urchin embryos and the expression of an orphan steroid receptor. | Journal of experimental zoology. Part A, Comparative experimental biology 20061001 |
Mineralocorticoid synthesis during the periovulatory interval in macaques. | Biology of reproduction 20061001 |
Carvedilol reduces aldosterone release in systolic heart failure. | Heart, lung & circulation 20061001 |
Effects of clonidine on diuretic response in ascitic patients with cirrhosis and activation of sympathetic nervous system. | Hepatology (Baltimore, Md.) 20061001 |
Aldosterone blockade in post-acute myocardial infarction heart failure. | Clinical cardiology 20061001 |
[Aldosterone-to-renin ratio threshold for screening primary aldosteronism in Chinese hypertensive patients]. | Zhonghua xin xue guan bing za zhi 20061001 |
Novel effect of mineralocorticoid receptor antagonism to reduce proinflammatory cytokines and hypothalamic activation in rats with ischemia-induced heart failure. | Circulation research 20060929 |
Neuroprotective effects of agmatine against cell damage caused by glucocorticoids in cultured rat hippocampal neurons. | Neuroscience 20060915 |
Aldosterone promotes fibronectin production through a Smad2-dependent TGF-beta1 pathway in mesangial cells. | Biochemical and biophysical research communications 20060915 |
Oral V2 receptor antagonist (RWJ-351647) in patients with cirrhosis and ascites: a randomized, double-blind, placebo-controlled, single ascending dose study. | Alimentary pharmacology & therapeutics 20060915 |
[Antihypertensive agents used as first line agents: beta-blockers under pressure]. | Revue medicale suisse 20060913 |
[The revived interest in aldosterone antagonists]. | Revue medicale suisse 20060913 |
Contrasting roles of corticosteroid receptors in hippocampal plasticity. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060906 |
Spironolactone and risk of upper gastrointestinal events: spironolactone may not be guilty. | BMJ (Clinical research ed.) 20060902 |
Spironolactone and risk of upper gastrointestinal events: causality remains unconvincing. | BMJ (Clinical research ed.) 20060902 |
Spironolactone and risk of upper gastrointestinal events: association is unproved. | BMJ (Clinical research ed.) 20060902 |
Activation of brain renin-angiotensin-aldosterone system by central sodium in Wistar rats. | American journal of physiology. Heart and circulatory physiology 20060901 |
Induction of rat intestinal P-glycoprotein by spironolactone and its effect on absorption of orally administered digoxin. | The Journal of pharmacology and experimental therapeutics 20060901 |
[Modern pharmacological aspects of hyperaldosteronism therapy]. | Der Internist 20060901 |
Aldosterone impairs bone marrow-derived progenitor cell formation. | Hypertension (Dallas, Tex. : 1979) 20060901 |
Eplerenone prevents adverse cardiac remodelling induced by pressure overload in atrial natriuretic peptide-null mice. | Clinical and experimental pharmacology & physiology 20060901 |
Mineralocorticoid receptor antagonist spironolactone prevents pig serum-induced hepatic fibrosis in rats. | Translational research : the journal of laboratory and clinical medicine 20060901 |
Ascites in childhood liver disease. | Indian journal of pediatrics 20060901 |
Tachycardiomyopathy induced by ventricular premature complexes: complete recovery after radiofrequency catheter ablation. | The Korean journal of internal medicine 20060901 |
Aldosterone antagonism in an inflammatory state: evidence for myocardial protection. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20060901 |
Combined treatment with valsartan and spironolactone prevents cardiovascular remodeling in renovascular hypertensive rats. | International heart journal 20060901 |
Selective aldosterone blockade with eplerenone reduces albuminuria in patients with type 2 diabetes. | Clinical journal of the American Society of Nephrology : CJASN 20060901 |
Eplerenone: hypertension, heart failure and the importance of mineralocorticoid receptor blockade. | Future cardiology 20060901 |
Spironolactone and risk of upper gastrointestinal events: population based case-control study. | BMJ (Clinical research ed.) 20060812 |
Rapid actions of aldosterone in vascular health and disease--friend or foe? | Pharmacology & therapeutics 20060801 |
Agents ameliorating or augmenting the nephrotoxicity of cisplatin and other platinum compounds: a review of some recent research. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060801 |
Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy. | Kidney international 20060801 |
Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy. | Circulation journal : official journal of the Japanese Circulation Society 20060801 |
Myxedema ascites: case report and literature review. | Journal of Korean medical science 20060801 |
External validity: the neglected dimension in evidence ranking. | Journal of evaluation in clinical practice 20060801 |
Statins in the treatment of chronic heart failure: a systematic review. | PLoS medicine 20060801 |
[Perceptions of heart failure diagnosis and management: comparison between clinical cardiologists and family doctors]. | Arquivos brasileiros de cardiologia 20060801 |
[A clinical analysis of 9 cases of Gitelman syndrome]. | Zhonghua nei ke za zhi 20060801 |
Effects of eplerenone and salt intake on left ventricular remodeling after myocardial infarction in rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20060801 |
Managing congestive heart failure in a general hospital in Malaysia. Are we keeping pace with evidence? | The Medical journal of Malaysia 20060801 |
Combination topical therapy in the treatment of acne. | Cutis 20060801 |
Development and validation of an HPLC method for the determination of spironolactone and its metabolites in paediatric plasma samples. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060724 |
Oxidative stress in aldosteronism. | Cardiovascular research 20060715 |
Flexible versus nonflexible mitral valve rings for congestive heart failure: differential durability of repair. | Circulation 20060704 |
Cardiac fibrogenesis in magnesium deficiency: a role for circulating angiotensin II and aldosterone. | American journal of physiology. Heart and circulatory physiology 20060701 |
ANG II-induced cardiac molecular and cellular events: role of aldosterone. | American journal of physiology. Heart and circulatory physiology 20060701 |
Effect of spironolactone and captopril on nitric oxide and S-nitrosothiol formation in kidney of L-NAME-treated rats. | Kidney international 20060701 |
11beta-hydroxysteroid dehydrogenase type 2 activity in hypothalamic paraventricular nucleus modulates sympathetic excitation. | Hypertension (Dallas, Tex. : 1979) 20060701 |
Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060701 |
Spironolactone ameliorates renal injury and connective tissue growth factor expression in type II diabetic rats. | Kidney international 20060701 |
Eplerenone inhibits tumour necrosis factor alpha shedding process by tumour necrosis factor alpha converting enzyme in monocytes from patients with congestive heart failure. | Heart (British Cardiac Society) 20060701 |
Serum- and glucocorticoid-inducible kinase 1 mediates salt sensitivity of glucose tolerance. | Diabetes 20060701 |
Efficacy of add-on aldosterone receptor blocker in uncontrolled hypertension. | American journal of hypertension 20060701 |
Anti-inflammatory effect of spironolactone on human peripheral blood mononuclear cells. | Journal of pharmacological sciences 20060701 |
The effect of spironolactone, cilazapril and their combination on albuminuria in patients with hypertension and diabetic nephropathy is independent of blood pressure reduction: a randomized controlled study. | Diabetic medicine : a journal of the British Diabetic Association 20060701 |
Spironolactone: an old friend rediscovered. | Journal of clinical hypertension (Greenwich, Conn.) 20060701 |
Addition of spironolactone to an angiotensin-converting enzyme inhibitor decreases lung congestion and edema in Dahl hypertensive rats. | Heart and vessels 20060701 |
Potassium-sparing diuretics. | Nursing times 20060701 |
Spironolactone with ACE inhibitor is effective in gross hematuria caused by nephroptosis. | International journal of urology : official journal of the Japanese Urological Association 20060701 |
[Cardiovascular action of aldosterone]. | Nihon rinsho. Japanese journal of clinical medicine 20060701 |
[Cardioprotective effect of aldosterone antagonists for ventricular remodeling]. | Nihon rinsho. Japanese journal of clinical medicine 20060701 |
[Old man with bosom]. | MMW Fortschritte der Medizin 20060629 |
[Testotoxicosis]. | Nihon rinsho. Japanese journal of clinical medicine 20060628 |
Relation of loop diuretic dose to mortality in advanced heart failure. | The American journal of cardiology 20060615 |
[Aldosterone receptor blockade after acute myocardial infarction with heart failure]. | Medizinische Klinik (Munich, Germany : 1983) 20060615 |
[Combination drug therapy after myocardial infarction. Early aldosterone blocking protects risk patients]. | MMW Fortschritte der Medizin 20060615 |
Long-term renal outcomes in patients with primary aldosteronism. | JAMA 20060614 |
Aldosterone increases voltage-gated sodium current in ventricular myocytes. | American journal of physiology. Heart and circulatory physiology 20060601 |
Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy. | The Journal of clinical endocrinology and metabolism 20060601 |
Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker. | Hypertension (Dallas, Tex. : 1979) 20060601 |
Can the dextroenantiomer of the aromatase inhibitor fadrozole be useful for clinical investigation of aldosterone-synthase inhibition? | Journal of hypertension 20060601 |
Investigation of aldosterone-synthase inhibition in rats. | Journal of hypertension 20060601 |
Evidence-based treatment and quality of life in heart failure. | Journal of evaluation in clinical practice 20060601 |
Confirmatory testing in normokalaemic primary aldosteronism: the value of the saline infusion test and urinary aldosterone metabolites. | European journal of endocrinology 20060601 |
The effects of thiazide and thiazide-potassium sparing diuretics on fibrinolytic system parameters. | Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20060601 |
Cost-effectiveness of eplerenone in patients with left ventricular dysfunction after myocardial infarction--an analysis of the EPHESUS study from a Swiss perspective. | Cardiovascular drugs and therapy 20060601 |
[Chronic effects of spironolactone in conjunction with an angiotensin-converting enzyme inhibitor enalapril on circulating procollagen marker P III NP and vascular resistance in patients with essential hypertension]. | Zhonghua xin xue guan bing za zhi 20060601 |
Adding spironolactone to conventional antihypertensives reduces albuminuria in patients with diabetic nephropathy. | Nature clinical practice. Nephrology 20060601 |
Hypokalemic nephropathy in an adult patient with partial empty sella: a classic Bartter's syndrome, a Gitelman's syndrome or both? | Panminerva medica 20060601 |
Valsartan in the treatment of heart attack survivors. | Vascular health and risk management 20060601 |
Pharmacologic interventions in aging hair. | Clinical interventions in aging 20060601 |
[Clinical characteristics of primary and secondary aldosteronism]. | Nihon rinsho. Japanese journal of clinical medicine 20060528 |
[Idiopathic hyperaldosteronism (IHA)]. | Nihon rinsho. Japanese journal of clinical medicine 20060528 |
[Corticosterone-producing adrenal tumor]. | Nihon rinsho. Japanese journal of clinical medicine 20060528 |
[Deoxycorticosterone-producing adrenal tumor]. | Nihon rinsho. Japanese journal of clinical medicine 20060528 |
[Deficiency of 11beta-hydroxysteroid dehydrogenase type 2 (syndrome of apparent mineralocorticoid excess)]. | Nihon rinsho. Japanese journal of clinical medicine 20060528 |
[11Beta-hydroxylase deficiency]. | Nihon rinsho. Japanese journal of clinical medicine 20060528 |
[Adrenocortical adenoma]. | Nihon rinsho. Japanese journal of clinical medicine 20060528 |
Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitin-mediated degradation of cyclin D1. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060517 |
A new phenanthrene with a spirolactone from Dendrobium chrysanthum and its anti-inflammatory activities. | Bioorganic & medicinal chemistry 20060515 |
A new approach to the furan degradation problem involving ozonolysis of the trans-enedione and its use in a cost-effective synthesis of eplerenone. | Organic letters 20060511 |
[Water-electrolyte imbalance: Reality in diagnosis and therapy (discussion)]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20060510 |
Current management of the complications of portal hypertension: variceal bleeding and ascites. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20060509 |
Lithium-induced NDI in rats is associated with loss of alpha-ENaC regulation by aldosterone in CCD. | American journal of physiology. Renal physiology 20060501 |
Spironolactone preserves cardiac norepinephrine reuptake in salt-sensitive Dahl rats. | Endocrinology 20060501 |
Protective effect of spironolactone on endothelial cell apoptosis. | Endocrinology 20060501 |
Evaluation of eplerenone in the subgroup of EPHESUS patients with baseline left ventricular ejection fraction <or=30%. | European journal of heart failure 20060501 |
Effects of spironolactone on human blood mononuclear cells: mineralocorticoid receptor independent effects on gene expression and late apoptosis induction. | British journal of pharmacology 20060501 |
Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. | Journal of the American Society of Nephrology : JASN 20060501 |
SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment. | Journal of molecular medicine (Berlin, Germany) 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Differential action of steroid hormones on human endothelium. | Journal of cell science 20060501 |
Spironolactone treatment and clinical outcomes in patients with systolic dysfunction and mild heart failure symptoms: a retrospective analysis. | Journal of cardiac failure 20060501 |
Selective aldosterone blockade suppresses atrial tachyarrhythmias in heart failure. | Journal of cardiovascular electrophysiology 20060501 |
Aldosterone antagonism as an antiarrhythmic approach for atrial arrhythmias in heart failure. | Journal of cardiovascular electrophysiology 20060501 |
[Aldosterone antagonist]. | Nihon rinsho. Japanese journal of clinical medicine 20060501 |
Aldosterone antagonists: effective add-on therapy for the treatment of resistant hypertension. | Expert review of cardiovascular therapy 20060501 |
[Cardiovascular medicine unit: preliminary results of an in-hospital multidisciplinary intervention in heart failure]. | Giornale italiano di cardiologia (2006) 20060501 |
[Antihypertensive drugs in clinical development]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20060501 |
Hypertension and ethnic group: eplerenone may have role in hypertension related atrial fibrillation. | BMJ (Clinical research ed.) 20060422 |
A 24 h corticosterone exposure exacerbates excitotoxic insult in rat hippocampal slice cultures independently of glucocorticoid receptor activation or protein synthesis. | Brain research 20060412 |
Aldosterone and the kidney: rapid regulation of renal microcirculation. | Steroids 20060401 |
Rapid anti-secretory effects of glucocorticoids in human airway epithelium. | Steroids 20060401 |
Eplerenone with valsartan effectively reduces atherosclerotic lesion by attenuation of oxidative stress and inflammation. | Arteriosclerosis, thrombosis, and vascular biology 20060401 |
Is it time for spironolactone therapy in dialysis patients? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060401 |
Cardioprotective effects of eplerenone in the rat heart: interaction with locally synthesized or blood-derived aldosterone? | Hypertension (Dallas, Tex. : 1979) 20060401 |
Mitigation of radiation nephropathy after internal alpha-particle irradiation of kidneys. | International journal of radiation oncology, biology, physics 20060401 |
Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20060401 |
Mineralocorticoid receptors and cardiovascular damage: it's not just aldosterone. | Hypertension (Dallas, Tex. : 1979) 20060401 |
Cardioprotective mechanisms of eplerenone on cardiac performance and remodeling in failing rat hearts. | Hypertension (Dallas, Tex. : 1979) 20060401 |
Spironolactone induces apoptosis in human mononuclear cells. Association between apoptosis and cytokine suppression. | Apoptosis : an international journal on programmed cell death 20060401 |
Simultaneous determination of spironolactone and its active metabolite canrenone in human plasma by HPLC-APCI-MS. | Journal of mass spectrometry : JMS 20060401 |
The pharmacological treatment of primary aldosteronism. | Expert opinion on pharmacotherapy 20060401 |
The prevalence of primary aldosteronism in diabetic patients. | Journal of clinical hypertension (Greenwich, Conn.) 20060401 |
Eplerenone: new drug. Recent myocardial infarction with heart failure: a spironolactone me too. | Prescrire international 20060401 |
Aldosterone receptor antagonists and cardiovascular disease: do we need a change of the guard? | Cardiovascular & hematological agents in medicinal chemistry 20060401 |
Appropriateness of spironolactone prescribing in heart failure patients: a population-based study. | Journal of cardiac failure 20060401 |
Aldosterone antagonism improves endothelial-dependent vasorelaxation in heart failure via upregulation of endothelial nitric oxide synthase production. | Journal of cardiac failure 20060401 |
Acute and concomitant deterioration of hyponatremia and renal dysfunction associated with heart and liver failure. | Clinical nephrology 20060401 |
The effects of treatment with octreotide, diuretics, or both on portal hemodynamics in nonazotemic cirrhotic patients with ascites. | Journal of clinical gastroenterology 20060401 |
Use and side-effect profile of spironolactone in a private cardiologist's practice. | Clinical cardiology 20060401 |
[41th Congress of EASD (European Association for The Study of Diabetes) 10 to 15 September 2005, Athens, Greece]. | La Revue de medecine interne 20060401 |
Treatment of premenstrual disorders. | The Journal of reproductive medicine 20060401 |
The antagonism of aldosterone receptor prevents the development of hypertensive heart failure induced by chronic inhibition of nitric oxide synthesis in rats. | Cardiovascular drugs and therapy 20060401 |
Combination therapy with aldosterone blockade and renin-angiotensin inhibitors confers organ protection. | Hypertension research : official journal of the Japanese Society of Hypertension 20060401 |
Precocious pseudopuberty with testicular enlargement. | Indian journal of pediatrics 20060401 |
[Normoaldosterone spironolactone sensitive hypertension]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20060401 |
[Effect of the optimal neurohormonal blockade on long-term survival in patients with chronic heart failure]. | Polskie Archiwum Medycyny Wewnetrznej 20060401 |
Isolation and identification of novel impurities in spironolactone. | Journal of pharmaceutical and biomedical analysis 20060318 |
CdSe quantum dots as luminescent probes for spironolactone determination. | Talanta 20060315 |
Expression of procollagen C-proteinase enhancer-1 in the remodeling rat heart is stimulated by aldosterone. | The international journal of biochemistry & cell biology 20060301 |
Direct effects of aldosterone on cardiomyocytes in the presence of normal and elevated extracellular sodium. | Endocrinology 20060301 |
Evidence-based prescribing of statins: a developing world perspective. | PLoS medicine 20060301 |
Effects of Saireito, a Japanese herbal medicine, on edema via antagonistic actions against aldosterone in anti-GBM nephritic rats. | Clinical and experimental nephrology 20060301 |
Aldosterone receptor antagonists for heart failure: current status, future indications. | Cleveland Clinic journal of medicine 20060301 |
[Myasthenia gravis and pregnancy: clinical course and management of delivery and the postpartum phase]. | Revue neurologique 20060301 |
Angiotensin receptor blockade with candesartan in heart failure: findings from the Candesartan in Heart failure--assessment of reduction in mortality and morbidity (CHARM) programme. | Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20060301 |
Compliance by referring physicians with recommendations on heart failure therapy from a tertiary center. | Journal of cardiovascular pharmacology and therapeutics 20060301 |
Metabolic and immunologic derangements in cardiac cachexia: where to from here? | Heart failure reviews 20060301 |
Aldosterone blockade over and above ACE-inhibitors in patients with coronary artery disease but without heart failure. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20060301 |
Differences between cardiac and arterial fibrosis and stiffness in aldosterone-salt rats: effect of eplerenone. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20060301 |
Beneficial effect of eplerenone on cardiac remodelling and electrical properties of the failing heart. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20060301 |
Consumption and costs of antihypertensive drugs in Mexico: are diuretic agents a standing technological trajectory? | Research in social & administrative pharmacy : RSAP 20060301 |
Double-blind, placebo-controlled study on the effect of the aldosterone receptor antagonist spironolactone in patients who have persistent proteinuria and are on long-term angiotensin-converting enzyme inhibitor therapy, with or without an angiotensin II receptor blocker. | Clinical journal of the American Society of Nephrology : CJASN 20060301 |
[Life threatening drug-induced hyperkaliemia--case report]. | Polskie Archiwum Medycyny Wewnetrznej 20060301 |
Mifepristone (RU-486) treatment for depression and psychosis: a review of the therapeutic implications. | Neuropsychiatric disease and treatment 20060301 |
Uptake of cardiovascular drugs into the human heart: expression, regulation, and function of the carnitine transporter OCTN2 (SLC22A5). | Circulation 20060227 |
Eplerenone suppresses neointimal formation after coronary stent implantation in swine. | International journal of cardiology 20060215 |
[Rhythm control and rate control as therapy for patients with atrial fibrillation]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20060210 |
How many patients with heart failure are eligible for cardiac resynchronization? Insights from two prospective cohorts. | European heart journal 20060201 |
Aldosterone increases urine production and decreases apical AQP2 expression in rats with diabetes insipidus. | American journal of physiology. Renal physiology 20060201 |
Mineralocorticoid receptor mediates glucocorticoid treatment effects in the autoimmune mouse ear. | Hearing research 20060201 |
[An unusual diagnostic of quadriparesia: hyperkalemic paralysis. Report of four non-familial cases]. | La Revue de medecine interne 20060201 |
Understanding the causes and management of hirsutism. | Nursing times 20060201 |
Effects of enalapril, tempol, and eplerenone on salt-induced hypertension in dahl salt-sensitive rats. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20060201 |
Dexamethasone induces cell death which may be blocked by NMDA receptor antagonists but is insensitive to Mg2+ in cerebellar granule neurons. | Brain research 20060127 |
Determinants of increased angiotensin II levels in severe chronic heart failure patients despite ACE inhibition. | International journal of cardiology 20060126 |
5-Aminooxazole as an internal traceless activator of C-terminal carboxylic acid: rapid access to diversely functionalized cyclodepsipeptides. | Chemistry (Weinheim an der Bergstrasse, Germany) 20060123 |
[The latest developments in endocrinology 2004/2005]. | Medizinische Klinik (Munich, Germany : 1983) 20060115 |
New progestagens for contraceptive use. | Human reproduction update 20060101 |
Are beta-blockers needed in patients receiving spironolactone for severe chronic heart failure? An analysis of the COPERNICUS study. | American heart journal 20060101 |
Aldosterone antagonists in the treatment of heart failure. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060101 |
Molecular mechanisms and therapeutic strategies of chronic renal injury: renoprotective effects of aldosterone blockade. | Journal of pharmacological sciences 20060101 |
Secondary hyperparathyroidism in patients with untreated and treated congestive heart failure. | The American journal of the medical sciences 20060101 |
[The use of transgenic animals in biomedical research in Germany. Part 2: Ethical evaluation of the use of transgenic animals in biomedical research and perspectives for the changeover in research to research animal-free methods]. | ALTEX 20060101 |
Introducing the concept of the 3Rs into tissue engineering research. | ALTEX 20060101 |
[Replacement of dogs as research animals for the approval testing of plant protection products]. | ALTEX 20060101 |
[The role of animal testing advisory committees in biomedical research in Germany]. | ALTEX 20060101 |
[The treatment of female pattern hair loss]. | Duodecim; laaketieteellinen aikakauskirja 20060101 |
Approach to leg edema of unclear etiology. | Journal of the American Board of Family Medicine : JABFM 20060101 |
Anemia and chronic kidney disease are associated with poor outcomes in heart failure patients. | BMC nephrology 20060101 |
[Hypokalemia--tubulopathia acqisita]. | Medicinski arhiv 20060101 |
Mineralocorticoid receptor blockade in the protection of target organ damage. | Cardiovascular & hematological agents in medicinal chemistry 20060101 |
Aldosterone stimulates activity and surface expression of NHE3 in human primary proximal tubule epithelial cells (RPTEC). | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101 |
Timing is essential for rapid effects of corticosterone on synaptic potentiation in the mouse hippocampus. | Learning & memory (Cold Spring Harbor, N.Y.) 20060101 |
Diurnal blood pressure pattern in patients with primary aldosteronism. | Journal of endocrinological investigation 20060101 |
Gitelman's syndrome with silent thyroiditis. | Nagoya journal of medical science 20060101 |
[Use of spironolactone and indapamide in the treatment of low-renin arterial hypertension]. | Terapevticheskii arkhiv 20060101 |
[Diuretic therapy in heart failure]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20060101 |
Premenstrual syndrome in adolescents: diagnosis and treatment. | Pediatric endocrinology reviews : PER 20060101 |
Preclinical development of new drugs that enhance thyroid hormone metabolism and clearance: inadequacy of using rats as an animal model for predicting human risks in an IND and NDA. | American journal of therapeutics 20060101 |
Hypoxia induced chemokine expression in nasal epithelial cells: development of an in vitro model for chronic rhinosinusitis. | ALTEX 20060101 |
[Bovine udder skin (BUS): testing of skin compatibility and skin protection]. | ALTEX 20060101 |
Spironolactone further reduces urinary albumin excretion and plasma B-type natriuretic peptide levels in hypertensive type II diabetes treated with angiotensin-converting enzyme inhibitor. | Clinical and experimental pharmacology & physiology 20060101 |
[Contemporary approaches to the treatment of chronic heart failure in adults (after materials of recommendations of American College of Cardiology and American Heart Association, 2005)]. | Kardiologiia 20060101 |
Use of aldosterone antagonists in resistant hypertension. | Progress in cardiovascular diseases 20060101 |
Complete atrioventricular canal. | Orphanet journal of rare diseases 20060101 |
Gitelman-like syndrome after cisplatin therapy: a case report and literature review. | BMC nephrology 20060101 |
Comparison of the epidemiology and co-morbidities of heart failure in the pediatric and adult populations: a retrospective, cross-sectional study. | BMC cardiovascular disorders 20060101 |
Aldosterone remodels human endothelium. | Acta physiologica (Oxford, England) 20060101 |
Diagnosis and management of polycystic ovary syndrome: a practical guide. | Drugs 20060101 |
Application of continuous positive airway pressure in hypoxemic acute respiratory failure associated with diastolic dysfunction in pregnancy. | Congestive heart failure (Greenwich, Conn.) 20060101 |
Serum cystatin C levels to predict serum concentration of digoxin in Japanese patients. | International journal of medical sciences 20060101 |
Aortic distensibility measured by pulse-wave velocity is not modified in patients with Chagas' disease. | Journal of negative results in biomedicine 20060101 |
Treatment of heart failure in Dutch general practice. | BMC family practice 20060101 |
Cardiomyopathy, familial dilated. | Orphanet journal of rare diseases 20060101 |
[Pulmonary hypertension and right ventricular failure. Part V. Therapy in the patients with chronic obstructive pulmonary disease]. | Kardiologiia 20060101 |
[Ascitic decompensation]. | Gastroenterologie clinique et biologique 20060101 |
Racial differences in potassium response to spironolactone in heart failure. | Congestive heart failure (Greenwich, Conn.) 20060101 |
Diuretics in pediatrics : current knowledge and future prospects. | Paediatric drugs 20060101 |
Coronary heart disease policy models: a systematic review. | BMC public health 20060101 |
Aldosterone blockage in proliferative glomerulonephritis prevents not only fibrosis, but proliferation as well. | Renal failure 20060101 |
Andersen-Tawil syndrome. | Indian pacing and electrophysiology journal 20060101 |
Single-chamber versus dual-chamber implantable cardioverter defibrillators: do we need physiologic pacing in the course? | Indian pacing and electrophysiology journal 20060101 |
Aldosterone and thrombosis formation: implications for ischemic and atherosclerotic heart disease. | Journal of endocrinological investigation 20060101 |
A new enzyme-linked chemiluminescent immunosorbent digoxin assay is virtually free from interference of spironolactone, potassium canrenoate, and their common metabolite canrenone. | Journal of clinical laboratory analysis 20060101 |
Premenstrual syndrome and premenstrual dysphoric disorder in adolescence. | Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 20060101 |
Pfizer launches Inspra for heart failure. | Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20060101 |
[Pathophysiology of heart failure]. | Archivos de cardiologia de Mexico 20060101 |
Management of heart failure in the elderly: recommendations from the French Society of Cardiology (SFC) and the French Society of Gerontology and Geriatrics (SFGG). | The journal of nutrition, health & aging 20060101 |
Anti-androgenic therapy using oral spironolactone for acne vulgaris in Asians. | Aesthetic plastic surgery 20060101 |
[The current revision of Directive 86/609/EWG from the perspective of animal welfare legislation]. | ALTEX 20060101 |
Towards eliminating the use of animals for regulatory required vaccine quality control. | ALTEX 20060101 |
Proposal for the composition of animal experiments committees in the Netherlands. | ALTEX 20060101 |
Computer-based alternatives in higher education--past, present and future. | ALTEX 20060101 |
[The isolated perfused porcine kidney model for investigations concerning surgical therapy procedures]. | ALTEX 20060101 |
[Austria: fewer experimental animals used in 2005]. | ALTEX 20060101 |
[What can a chair on alternatives to animal experimentation effectuate?]. | ALTEX 20060101 |
Eplerenone reduces morbidity and mortality after acute MI. | Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20060101 |
Changes in heart failure medications in patients hospitalised and discharged. | BMC family practice 20060101 |
Direct aldosterone action on mouse cardiomyocytes detected with atomic force microscopy. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101 |
Aldosterone antagonists: a new treatment option for patients with post-myocardial infarction heart failure. | Cardiovascular revascularization medicine : including molecular interventions 20060101 |
[Perception independent of interest: a contribution to the relationship between people and animals]. | ALTEX 20060101 |
The question of a right to life in animal ethics. | ALTEX 20060101 |
Animals have a right to life. | ALTEX 20060101 |
Genetically modified laboratory animals in the name of the 3Rs? | ALTEX 20060101 |
Differences in selected zinc metabolism parameters in obese and normal-weight hypertensive patients following treatment with spironolactone. | Biological trace element research 20060101 |
Laparoscopic wedge resection of gastric leiomyoma. | JSLS : Journal of the Society of Laparoendoscopic Surgeons 20060101 |
Research on primates--an ethical evaluation. | ALTEX 20060101 |
UK/EU: alternatives progress in Russia and Ukraine. | ALTEX 20060101 |
Therapeutic drug monitoring of digoxin: impact of endogenous and exogenous digoxin-like immunoreactive substances. | Toxicological reviews 20060101 |
[Clinical and epidemiologic aspects of attention deficit hyperactivity syndrome (ADHD) in ambulatory practice]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101 |
[Reconstructive surgical procedures in the treatment of tissue defects of cervico-facial oncological pathology]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101 |
[Effect of spironolactone on mortality in patients with severe left ventricular dysfunction after acute myocardial infarction]. | Przeglad lekarski 20060101 |
A comparison of theoretical methods of calculation of partition coefficients for selected drugs. | Acta poloniae pharmaceutica 20060101 |
Proceedings of the 5th World Congress on Alternatives and Animal Use in the Life Sciences, Berlin 2005. | ALTEX 20060101 |
Biventricular pacing and heterogeneity of ventricular repolarization in heart failure patients. | Heart international 20060101 |
Enhanced External Counterpulsation (EECP): An Evidence-Based Analysis. | Ontario health technology assessment series 20060101 |
A case of intolerance to warfarin dosing in an intermediate metabolizer of CYP2C9. | Yonsei medical journal 20051231 |
The hypothalamopituitary-adrenal axis and alcohol preference. | Brain research bulletin 20051230 |
Effects of eplerenone on transcriptional factors and mRNA expression related to cardiac remodelling after myocardial infarction. | Heart (British Cardiac Society) 20051201 |
Utilization of evidence-based therapies for heart failure in the institutionalized elderly. | European journal of heart failure 20051201 |
Under-utilization of evidence-based drug treatment in patients with heart failure is only partially explained by dissimilarity to patients enrolled in landmark trials: a report from the Euro Heart Survey on Heart Failure. | European heart journal 20051201 |
Mechanisms for nongenomic and genomic effects of aldosterone on Na+/H+ exchange in vascular smooth muscle cells. | Journal of hypertension 20051201 |
Aldosterone antagonists in the treatment and prevention of heart failure. | Current treatment options in cardiovascular medicine 20051201 |
Bilateral renal artery stenosis and primary aldosteronism in a diabetic patient. | QJM : monthly journal of the Association of Physicians 20051201 |
Chronic heart failure: an overview of conventional treatment versus novel approaches. | Nature clinical practice. Cardiovascular medicine 20051201 |
Beneficial impact of spironolactone in diabetic nephropathy. | Kidney international 20051201 |
Serum concentration of potassium in chronic heart failure patients administered spironolactone plus furosemide and either enalapril maleate, losartan potassium or candesartan cilexetil. | Journal of clinical pharmacy and therapeutics 20051201 |
Economic implications of treatment guidelines for congestive heart failure. | The Canadian journal of cardiology 20051201 |
Aldosterone receptor antagonists in the medical management of chronic heart failure. | Mayo Clinic proceedings 20051201 |
Comparison of the clinical efficacy of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism: a randomized controlled study. | Fertility and sterility 20051201 |
Does aldosterone-to-renin ratio predict the antihypertensive effect of the aldosterone antagonist spironolactone? | American journal of hypertension 20051201 |
[Heart failure after myocardial infarction. Increased risk, poorer treatment]. | MMW Fortschritte der Medizin 20051201 |
[Efficient improvement of prognosis after myocardial infarct? Additional aldosterone inhibition is required]. | MMW Fortschritte der Medizin 20051201 |
The acute anticonvulsant effects of deoxycorticosterone in developing rats: role of metabolites and mineralocorticoid-receptor responses. | Epilepsia 20051201 |
Polycystic ovary syndrome. | Clinical evidence 20051201 |
Diagnosis of adenomatous primary aldosteronism in a patient with severe hypertension. | Nature clinical practice. Endocrinology & metabolism 20051201 |
Cardiovascular consequences of cortisol excess. | Vascular health and risk management 20051201 |
Extracellular zinc and ATP-gated P2X receptor calcium entry channels: New zinc receptors as physiological sensors and therapeutic targets. | Purinergic signalling 20051201 |
Stimulation of testosterone production in rat Leydig cells by aldosterone is mineralocorticoid receptor mediated. | Molecular and cellular endocrinology 20051124 |
Mineralocorticoid receptor antagonism ameliorates left ventricular diastolic dysfunction and myocardial fibrosis in mildly symptomatic patients with idiopathic dilated cardiomyopathy: a pilot study. | Circulation 20051108 |
[Successful resuscitation of a patient with hyperkalemic cardiac arrest by emergency hemodiafiltration]. | Der Anaesthesist 20051101 |
Renocortical mRNA expression of vasoactive factors during spironolactone protective effect in chronic cyclosporine nephrotoxicity. | American journal of physiology. Renal physiology 20051101 |
Association of Lys173Arg polymorphism with CYP11B2 expression in normal adrenal glands and aldosterone-producing adenomas. | The Journal of clinical endocrinology and metabolism 20051101 |
Central role for ENaC in development of hypertension. | Journal of the American Society of Nephrology : JASN 20051101 |
Regression of existing glomerulosclerosis by inhibition of aldosterone. | Journal of the American Society of Nephrology : JASN 20051101 |
Eplerenone inhibits atherosclerosis in nonhuman primates. | Hypertension (Dallas, Tex. : 1979) 20051101 |
Eplerenone antagonizes atherosclerosis, but what is the agonist? | Hypertension (Dallas, Tex. : 1979) 20051101 |
N-acetylcysteine attenuates the progression of chronic renal failure. | Kidney international 20051101 |
A landmark for popperian epidemiology: refutation of the randomised Aldactone evaluation study. | Journal of epidemiology and community health 20051101 |
Life-threatening hypokalaemia on a low-carbohydrate diet associated with previously undiagnosed primary hyperaldosteronism [corrected]. | Diabetic medicine : a journal of the British Diabetic Association 20051101 |
Long-term effect of spironolactone on cardiac structure as assessed by analysis of ultrasonic radio-frequency signals in patients with ventricular hypertrophy. | Circulation journal : official journal of the Japanese Circulation Society 20051101 |
[A case of pancreatic cancer complicated by gemcitabine-induced peripheral edema]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051101 |
Electrocardiogram changes in hyperkalemia: there and back again. | The Israel Medical Association journal : IMAJ 20051101 |
Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy. | Canadian journal of physiology and pharmacology 20051101 |
Comparative pilot study of repeated large volume paracentesis vs the combination on clonidine-spironolactone in the treatment of cirrhosis-associated refractory ascites. | Gastroenterologie clinique et biologique 20051101 |
Cardioprotective mechanisms of spironolactone associated with the angiotensin-converting enzyme/epidermal growth factor receptor/extracellular signal-regulated kinases, NAD(P)H oxidase/lectin-like oxidized low-density lipoprotein receptor-1, and Rho-kinase pathways in aldosterone/salt-induced hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20051101 |
Mineralocorticoid-receptor blockade, hypertension and heart failure. | Nature clinical practice. Endocrinology & metabolism 20051101 |
The evaluation and treatment of hirsute women. | Women's health (London, England) 20051101 |
Rapid effects of dexamethasone on intracellular pH and Na+/H+ exchanger activity in human bronchial epithelial cells. | The Journal of biological chemistry 20051028 |
Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients. | Circulation research 20051028 |
Aldosterone increases osteopontin gene expression in rat endothelial cells. | Biochemical and biophysical research communications 20051014 |
Effects of spironolactone and eprosartan on cardiac remodeling and angiotensin-converting enzyme isoforms in rats with experimental heart failure. | American journal of physiology. Heart and circulatory physiology 20051001 |
Cardiorenal abnormalities associated with high sodium intake: correction by spironolactone in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20051001 |
Hypothalamus-pituitary-adrenal hyperactivity in human aging is partially refractory to stimulation by mineralocorticoid receptor blockade. | The Journal of clinical endocrinology and metabolism 20051001 |
Aldosterone stimulates vascular smooth muscle cell proliferation via big mitogen-activated protein kinase 1 activation. | Hypertension (Dallas, Tex. : 1979) 20051001 |
Effects of spironolactone and RU486 on gene expression and cell proliferation after freshwater transfer in the euryhaline killifish. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20051001 |
Spironolactone reduces fibrosis of dilated atria during heart failure in rats with myocardial infarction. | European heart journal 20051001 |
Aldosterone antagonism and atrial fibrillation: time for clinical assessment? | European heart journal 20051001 |
Nongenomic effects of aldosterone in the human heart: interaction with angiotensin II. | Hypertension (Dallas, Tex. : 1979) 20051001 |
The role of aldosterone antagonists in the management of resistant hypertension. | Current hypertension reports 20051001 |
Urinary prostasin: a candidate marker of epithelial sodium channel activation in humans. | Hypertension (Dallas, Tex. : 1979) 20051001 |
Role of aldosterone in diabetic nephropathy. | Nephrology (Carlton, Vic.) 20051001 |
Pharmacology of different progestogens: the special case of drospirenone. | Climacteric : the journal of the International Menopause Society 20051001 |
Importance of controlling blood pressure. | Climacteric : the journal of the International Menopause Society 20051001 |
Update on outpatient treatment of systolic heart failure. | American family physician 20051001 |
High prevalence of microalbuminuria in chronic heart failure patients. | Journal of cardiac failure 20051001 |
Spironolactone improves diastolic function in the elderly. | Clinical cardiology 20051001 |
Angiotensin II receptor antagonists and heart failure: angiotensin-converting-enzyme inhibitors remain the first-line option. | Prescrire international 20051001 |
[Normoaldosterone spironolactone sensitive hypertension--a case report]. | Polskie Archiwum Medycyny Wewnetrznej 20051001 |
Laparoscopic adrenalectomy. | Journal of minimal access surgery 20051001 |
[Adherence to guidelines in CHF therapy in Germany]. | Deutsche medizinische Wochenschrift (1946) 20050930 |
Sudden death in patients with myocardial infarction. | The New England journal of medicine 20050922 |
[A patient with severe hyperkalaemia -- an emergency after RALES]. | Deutsche medizinische Wochenschrift (1946) 20050909 |
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. | Journal of medicinal chemistry 20050908 |
The adequacy of laboratory monitoring in patients treated with spironolactone for congestive heart failure. | Journal of the American College of Cardiology 20050906 |
A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor. | The Journal of biological chemistry 20050902 |
Aldosterone and angiotensin II synergistically induce mitogenic response in vascular smooth muscle cells. | Circulation research 20050902 |
Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways. | Drug metabolism and disposition: the biological fate of chemicals 20050901 |
Aldosterone induces angiotensin converting enzyme gene expression via a JAK2-dependent pathway in rat endothelial cells. | Endocrinology 20050901 |
Prevention of cardiac remodeling after myocardial infarction in transgenic rats deficient in brain angiotensinogen. | Journal of molecular and cellular cardiology 20050901 |
Cultured embryonic hippocampal neurons deficient in glucocorticoid (GC) receptor: a novel model for studying nongenomic effects of GC in the neural system. | Endocrinology 20050901 |
A role for mineralocorticoid receptor blockade in the prevention of apoptosis. | Journal of molecular and cellular cardiology 20050901 |
Spironolactone and its main metabolite canrenoic acid block hKv1.5, Kv4.3 and Kv7.1 + minK channels. | British journal of pharmacology 20050901 |
Spironolactone improves carotid artery fibrosis and distensibility in rat post-ischaemic heart failure. | Journal of molecular and cellular cardiology 20050901 |
Aldosterone stimulates matrix metalloproteinases and reactive oxygen species in adult rat ventricular cardiomyocytes. | Hypertension (Dallas, Tex. : 1979) 20050901 |
Spironolactone for hirsutism in polycystic ovary syndrome. | The Annals of pharmacotherapy 20050901 |
Heart failure due to left ventricular systolic dysfunction: treatment at discharge from hospital and at one year. | International journal of cardiology 20050901 |
Improvement in blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension. | Hypertension (Dallas, Tex. : 1979) 20050901 |
Improvement of blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension. | Hypertension (Dallas, Tex. : 1979) 20050901 |
Beneficial effects of adding spironolactone to recommended antihypertensive treatment in diabetic nephropathy: a randomized, double-masked, cross-over study. | Diabetes care 20050901 |
Brain natriuretic peptide and optimal management of heart failure. | Journal of Zhejiang University. Science. B 20050901 |
Chondrocalcinosis secondary to hypomagnesemia in Gitelman's syndrome. | The Journal of rheumatology 20050901 |
Effects of eplerenone versus losartan in patients with low-renin hypertension. | American heart journal 20050901 |
Hepatic hydrothorax. | British journal of hospital medicine (London, England : 2005) 20050901 |
Beneficial cardiovascular actions of eplerenone in the spontaneously hypertensive rat. | Journal of cardiovascular pharmacology and therapeutics 20050901 |
Insulin resistance in polycystic ovarian disease. | Southern medical journal 20050901 |
Diagnosis and treatment of polycystic ovarian syndrome and insulin resistance. | Pediatric annals 20050901 |
Long-term follow-up of a girl with primary aldosteronism: effect of potassium supplement. | Acta paediatrica (Oslo, Norway : 1992) 20050901 |
Guidelines for choosing drugs in chronic heart failure. | Vascular health and risk management 20050901 |
[Polycystic ovary syndrome. New pathophysiological discoveries--therapeutic consequences]. | Ugeskrift for laeger 20050822 |
CAR and PXR: xenosensors of endocrine disrupters? | Chemico-biological interactions 20050815 |
[The effect of tubular epithelial cells activated by aldosterone on renal interstitial fibroblasts in co-culture system]. | Zhonghua yi xue za zhi 20050803 |
Eplerenone reduces mortality 30 days after randomization following acute myocardial infarction in patients with left ventricular systolic dysfunction and heart failure. | Journal of the American College of Cardiology 20050802 |
Letter regarding article by Weintraub et al, 'Cost-effectiveness of eplerenone compared with placebo in patients with myocardial infarction complicated by left ventricular dysfunction and heart failure'. | Circulation 20050802 |
Adherence to guidelines is a predictor of outcome in chronic heart failure: the MAHLER survey. | European heart journal 20050801 |
Renal effects of treatment with diuretics, octreotide or both, in non-azotemic cirrhotic patients with ascites. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050801 |
Aldosterone induces myocyte apoptosis in the heart and skeletal muscles of rats in vivo. | Journal of molecular and cellular cardiology 20050801 |
Aldosterone increases T-type calcium channel expression and in vitro beating frequency in neonatal rat cardiomyocytes. | Cardiovascular research 20050801 |
Bone mineral density and bone turnover in patients with Bartter syndrome. | Pediatric nephrology (Berlin, Germany) 20050801 |
Acute purulent pericarditis in pneumococcal meningitis. | Intensive care medicine 20050801 |
Human renal mesangial cells produce aldosterone in response to low-density lipoprotein (LDL). | The Journal of steroid biochemistry and molecular biology 20050801 |
Differing effects of mineralocorticoid receptor-dependent and -independent potassium-sparing diuretics on fibrinolytic balance. | Hypertension (Dallas, Tex. : 1979) 20050801 |
The risks and benefits of aldosterone antagonists. | Current heart failure reports 20050801 |
Screening procedure for detection of diuretics and uricosurics and/or their metabolites in human urine using gas chromatography-mass spectrometry after extractive methylation. | Therapeutic drug monitoring 20050801 |
Euro heart failure survey. Medical treatment not in line with current guidelines. | Zeitschrift fur Kardiologie 20050801 |
Short- and long-term results of a programme for the prevention of readmissions and mortality in patients with heart failure: are effects maintained after stopping the programme? | European journal of heart failure 20050801 |
Practical recommendations for the use of ACE inhibitors, beta-blockers, aldosterone antagonists and angiotensin receptor blockers in heart failure: putting guidelines into practice. | European journal of heart failure 20050801 |
C-reactive protein co-expresses with tumor necrosis factor-alpha in the myocardium in human dilated cardiomyopathy. | European journal of heart failure 20050801 |
Responses in extracellular and intracellular calcium and magnesium in aldosteronism. | The Journal of laboratory and clinical medicine 20050801 |
Molecular mechanisms of mineralocorticoid receptor antagonism by eplerenone. | Mini reviews in medicinal chemistry 20050801 |
Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus. | The European journal of neuroscience 20050801 |
Heart failure after acute ST-segment elevation myocardial infarction: what should we do about it? | Clinical cardiology 20050801 |
[Severe hyperkalemia associated to the use of losartan and spironolactone: case report]. | Revista medica de Chile 20050801 |
Magnesium supplementation and muscle function in patients with alcoholic liver disease: a randomized, placebo-controlled trial. | Scandinavian journal of gastroenterology 20050801 |
New aldosteron receptor inhibitors in heart failure. | Minerva cardioangiologica 20050801 |
Aldosterone receptor antagonism in heart failure. | Pharmacotherapy 20050801 |
Aldosterone increases plasminogen activator inhibitor-1 synthesis in rat cardiomyocytes. | Molecular and cellular endocrinology 20050715 |
[Roll of aldosterone in pathogenesis of kidney disorders]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20050710 |
[Heart failure after acute myocardial infarct. Early aldosterone blockade increases survival rate]. | MMW Fortschritte der Medizin 20050707 |
[Neurohumoral systems escape control. Heart failure symptoms even once--long-term high risk prognosis]. | MMW Fortschritte der Medizin 20050707 |
Adoption of spironolactone therapy for older patients with heart failure and left ventricular systolic dysfunction in the United States, 1998-2001. | Circulation 20050705 |
Diuretics and bone loss in rats with aldosteronism. | Journal of the American College of Cardiology 20050705 |
Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats. | Journal of neural transmission (Vienna, Austria : 1996) 20050701 |
Human mineralocorticoid receptor expression renders cells responsive for nongenotropic aldosterone actions. | Molecular endocrinology (Baltimore, Md.) 20050701 |
Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver. | Drug metabolism and disposition: the biological fate of chemicals 20050701 |
Genomic and nongenomic effects of aldosterone in the rat heart: why is spironolactone cardioprotective? | British journal of pharmacology 20050701 |
Endothelin-induced increased aldosterone activity mediates augmented distal nephron acidification as a result of dietary protein. | Journal of the American Society of Nephrology : JASN 20050701 |
Utilisation of medications recommended for chronic heart failure and the relationship with annual hospitalisation duration in patients over 75 years of age. A pharmacoepidemiological study. | European journal of clinical pharmacology 20050701 |
Additive amelioration of left ventricular remodeling and molecular alterations by combined aldosterone and angiotensin receptor blockade after myocardial infarction. | Cardiovascular research 20050701 |
Pharmacokinetics of eplerenone after single and multiple dosing in subjects with and without renal impairment. | Journal of clinical pharmacology 20050701 |
Tolerability of spironolactone as adjunctive treatment for heart failure in patients over 75 years of age. | Age and ageing 20050701 |
Aldosterone nongenomically worsens ischemia via protein kinase C-dependent pathways in hypoperfused canine hearts. | Hypertension (Dallas, Tex. : 1979) 20050701 |
Angiotensin-converting enzyme inhibitors and angiotensin II type I receptor blockers in the management of congestive heart failure patients: what have we learned from recent clinical trials? | Current opinion in cardiology 20050701 |
Heart failure with preserved left ventricular systolic function: a hospital cohort study. | Heart (British Cardiac Society) 20050701 |
Antagonists of aldosterone and proteinuria in patients with CKD: an uncontrolled pilot study. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20050701 |
Effect of spironolactone on blood pressure and the renin-angiotensin-aldosterone system in oligo-anuric hemodialysis patients. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20050701 |
Selective insensitivity of ZR-75-1 human breast cancer cells to 2-methoxyestradiol: evidence for type II 17beta-hydroxysteroid dehydrogenase as the underlying cause. | Cancer research 20050701 |
New strategies for treatment of heart failure with aldosterone antagonists and the risk of hyperkalaemia. | Expert opinion on drug safety 20050701 |
Bone loss in rats with aldosteronism. | The American journal of the medical sciences 20050701 |
[Explanation on indications and cost-efficiency of Inspra]. | Lakartidningen 20050701 |
[Inspra and the drug benefits board: What is the role of the drug committees?]. | Lakartidningen 20050701 |
Pericryptal myofibroblast growth in rat descending colon induced by low-sodium diets is mediated by aldosterone and not by angiotensin II. | The Journal of membrane biology 20050701 |
Influence of aminoglutethimide and spironolactone on the efficacy of carbamazepine and diphenylhydantoin against amygdala-kindled seizures in rats. | European journal of pharmacology 20050615 |
Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias. | Circulation 20050614 |
Disruption of mineralocorticoid receptor function increases corticosterone responding to a mild, but not moderate, psychological stressor. | American journal of physiology. Endocrinology and metabolism 20050601 |
The ligand-dependent interaction of mineralocorticoid receptor with coactivator and corepressor peptides suggests multiple activation mechanisms. | Molecular endocrinology (Baltimore, Md.) 20050601 |
Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities. | Journal of lipid research 20050601 |
The effect of spironolactone on experimental periodontitis in rats. | Journal of periodontal research 20050601 |
Participation of aldosterone in the vascular inflammatory response of spontaneously hypertensive rats: role of the NFkappaB/IkappaB system. | Journal of hypertension 20050601 |
Clinical factors associated with hyperkalemia in patients with congestive heart failure. | Journal of clinical pharmacy and therapeutics 20050601 |
Aldosterone antagonism: an emerging strategy for effective blood pressure lowering. | Current hypertension reports 20050601 |
Aldosterone receptor antagonists: biology and novel therapeutic applications. | Current hypertension reports 20050601 |
Primary hyperaldosteronism in the cat: a series of 13 cases. | Journal of feline medicine and surgery 20050601 |
Conn's syndrome presenting as depression. | The American journal of psychiatry 20050601 |
Stability of spironolactone in rat plasma: strict temperature control of blood and plasma samples is required in rat pharmacokinetic studies. | Biological & pharmaceutical bulletin 20050601 |
Treatment of edema. | American family physician 20050601 |
Meditation reduces sympathetic activation and improves the quality of life in elderly patients with optimally treated heart failure: a prospective randomized study. | Journal of alternative and complementary medicine (New York, N.Y.) 20050601 |
[An addition concerning spironolactone and eplerenone (Inspra) in heart failure]. | Lakartidningen 20050601 |
[Recent insights into the role of aldosterone in physiology, pathology and therapy]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050601 |
Clinical implications of changes in hepatic drug metabolism in older people. | Therapeutics and clinical risk management 20050601 |
[Primary aldosteronism: analysis of a series of 54 patients]. | Medicina clinica 20050528 |
Persistent cardiac aldosterone synthesis in angiotensin II type 1A receptor-knockout mice after myocardial infarction. | Circulation 20050503 |
Blockade of brain mineralocorticoid receptors or Na+ channels prevents sympathetic hyperactivity and improves cardiac function in rats post-MI. | American journal of physiology. Heart and circulatory physiology 20050501 |
The Met852 residue is a key organizer of the ligand-binding cavity of the human mineralocorticoid receptor. | Molecular pharmacology 20050501 |
Treatment with angiotensin converting enzyme inhibitors, angiotensin-II-antagonists and beta-blockers in an unselected group of patients with chronic heart failure. | European journal of clinical pharmacology 20050501 |
Relative glomerular hyperfiltration in primary aldosteronism. | Journal of the American Society of Nephrology : JASN 20050501 |
Clinical experience with spironolactone in pediatrics. | The Annals of pharmacotherapy 20050501 |
Geriatric heart diseases in dogs. | The Veterinary clinics of North America. Small animal practice 20050501 |
Aldosterone receptor blockade prevents the transition to cardiac pump dysfunction induced by beta-adrenoreceptor activation. | Hypertension (Dallas, Tex. : 1979) 20050501 |
Spironolactone reduces brachial pulse wave velocity and PIIINP levels in hypertensive diabetic patients. | British journal of clinical pharmacology 20050501 |
Corticosterone increases damage and cytosolic calcium accumulation associated with ethanol withdrawal in rat hippocampal slice cultures. | Alcoholism, clinical and experimental research 20050501 |
Sixteen-slice computed tomography, transthoracic real-time 3-dimensional echocardiography and magnetic resonance imaging assessment of a long-term survivor of rupture of sinus of valsalva aneurysm. | Internal medicine (Tokyo, Japan) 20050501 |
[The role of aldosterone in the development of postinfarction fibrosis]. | Italian heart journal : official journal of the Italian Federation of Cardiology 20050501 |
[The AREA IN-CHF trial (antiremodeling effect of aldosterone receptors blockade with canrenone in mild chronic heart failure): rationale and design]. | Italian heart journal : official journal of the Italian Federation of Cardiology 20050501 |
Gitelman's syndrome presenting as intolerance to statin therapy. | Annals of clinical biochemistry 20050501 |
[LFN's evaluation of Inspra illustrates the need of drug committees!]. | Lakartidningen 20050501 |
[Ineffective atrial pacing and cardiac arrest in a 80-year old woman with hyperkalemia]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050501 |
Overexpression of the mineralocorticoid receptor protects against injury in PC12 cells. | Brain research. Molecular brain research 20050427 |
[Management of end-stage heart failure]. | Revue medicale suisse 20050427 |
Population-based drug-induced agranulocytosis. | Archives of internal medicine 20050425 |
[The role of aldosterone-antagonists in the treatment of congestive heart failure]. | Orvosi hetilap 20050403 |
Effect of losartan and spironolactone on left ventricular mass and heart sympathetic activity in prehypertensive obese subjects: a 16-week randomized trial. | Journal of human hypertension 20050401 |
Eplerenone shows renoprotective effect by reducing LOX-1-mediated adhesion molecule, PKCepsilon-MAPK-p90RSK, and Rho-kinase pathway. | Hypertension (Dallas, Tex. : 1979) 20050401 |
Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells. | Circulation research 20050401 |
[Effects of the RALE study. Hyperkalemia following spironolactone treatment]. | Der Internist 20050401 |
Hyponatremia with consciousness disturbance associated with esomeprazole. | The Annals of pharmacotherapy 20050401 |
The human mineralocorticoid receptor only partially differentiates between different ligands after expression in fission yeast. | FEMS yeast research 20050401 |
Spinal glucocorticoid receptors contribute to the development of morphine tolerance in rats. | Anesthesiology 20050401 |
Aldosterone as a cardiovascular risk factor. | Trends in endocrinology and metabolism: TEM 20050401 |
[Reduction in heart failure hospitalization rate during the first year of follow-up at a multidisciplinary unit]. | Revista espanola de cardiologia 20050401 |
[Long-term trends in drug prescription for hospitalized patients with congestive heart failure. Influence of type of dysfunction]. | Revista espanola de cardiologia 20050401 |
Ratio spectra derivative spectrophotometry for the determination of furosemide and spironolactone in a capsule formulation. | Farmaco (Societa chimica italiana : 1989) 20050401 |
Gynecomastia and hypertension. | Journal of clinical hypertension (Greenwich, Conn.) 20050401 |
[Effect of spironolactone on left ventricular remodeling in patients with acute myocardial infarction]. | Zhonghua xin xue guan bing za zhi 20050401 |
[Hyperkalemia: the new killer?]. | Revue medicale de Liege 20050401 |
Embolic infarction associated with cardiac amyloidosis. | Journal of clinical neurology (Seoul, Korea) 20050401 |
Design of therapy for advanced heart failure. | European journal of heart failure 20050316 |
How much responsibility should heart failure nurses take? | European journal of heart failure 20050316 |
Management of heart failure in The Netherlands. | European journal of heart failure 20050316 |
Effects of a nurse-led, clinic and home-based intervention on recurrent hospital use in chronic heart failure. | European journal of heart failure 20050316 |
Pharmacological treatment of congestive heart failure in Canada: a description of care in five provinces. | The Canadian journal of cardiology 20050315 |
Implantable cardioverter-defibrillator therapy after myocardial infarction. | The New England journal of medicine 20050310 |
Hyperkalemia associated with spironolactone therapy. | Canadian family physician Medecin de famille canadien 20050310 |
Cost-effectiveness of eplerenone compared with placebo in patients with myocardial infarction complicated by left ventricular dysfunction and heart failure. | Circulation 20050308 |
Eplerenone blocks nongenomic effects of aldosterone on the Na+/H+ exchanger, intracellular Ca2+ levels, and vasoconstriction in mesenteric resistance vessels. | Endocrinology 20050301 |
Glucocorticoid receptor blockade disinhibits pituitary-adrenal activity during the stress hyporesponsive period of the mouse. | Endocrinology 20050301 |
Combination therapy with ACE inhibitors and angiotensin II receptor blockers to halt progression of chronic renal disease: pathophysiology and indications. | Kidney international 20050301 |
Managed care patients with heart failure: spectrum of ventricular dysfunction and predictors of medication utilization. | Journal of cardiac failure 20050301 |
Clear cell type of renal cell carcinoma with numerous hyaline globules: a diagnostic pitfall. | Pathology international 20050301 |
Angiotensin II, angiotensin II antagonists and spironolactone and their modulation of cardiac repolarization. | Trends in pharmacological sciences 20050301 |
Effects and side-effects of spironolactone therapy in women with acne. | Journal of the European Academy of Dermatology and Venereology : JEADV 20050301 |
Treatment of female pattern hair loss with oral antiandrogens. | The British journal of dermatology 20050301 |
[Aldosterone and aldosterone antagonists. Eplerenone in cardiac insufficiency after myocardial infarction]. | Medizinische Monatsschrift fur Pharmazeuten 20050301 |
[Randomized Aldactone Evaluation Study (RALES)]. | Nihon rinsho. Japanese journal of clinical medicine 20050301 |
[Eplerenone Post-AMI Heart Failure Efficacy and survival study (EPHESUS)]. | Nihon rinsho. Japanese journal of clinical medicine 20050301 |
Nanosuspension formulations for low-soluble drugs: pharmacokinetic evaluation using spironolactone as model compound. | Drug development and industrial pharmacy 20050301 |
[A case of lactic acidosis caused by buformin in an oldest elderly diabetic patient]. | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20050301 |
Non-antiarrhythmic drugs for the prevention of cardiac arrhythmias. | Italian heart journal : official journal of the Italian Federation of Cardiology 20050301 |
Enhancement of beta-adrenergic cAMP-signaling by the mineralocorticoid receptor. | Molecular and cellular endocrinology 20050227 |
Hyperparathyroidism and the calcium paradox of aldosteronism. | Circulation 20050222 |
[Aldosterone antagonist therapy for chronic heart failure]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20050210 |
Effects of eplerenone, a selective aldosterone blocker, on the progression of left ventricular dysfunction and remodeling in rats with dilated cardiomyopathy. | Pharmacology 20050201 |
Blockage of glucocorticoid, but not mineralocorticoid receptors prevents the persistent increase in circulating basal corticosterone concentrations following stress in the rat. | Neuroscience letters 20050201 |
Ga-67 citrate and F-18 FDG uptake in spironolactone-induced gynecomastia. | Clinical nuclear medicine 20050201 |
Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2. | Biochemical pharmacology 20050201 |
Factors influencing medical treatment of heart failure patients in Spanish internal medicine departments: a national survey. | QJM : monthly journal of the Association of Physicians 20050201 |
Aldosterone does not mediate angiotensin II-induced atherosclerosis and abdominal aortic aneurysms. | British journal of pharmacology 20050201 |
ACE inhibitors and mineralocorticoid receptor blockade in patients with congestive heart failure. | Current diabetes reports 20050201 |
Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload. | Circulation 20050201 |
[Aldosterone and magnesium]. | Clinical calcium 20050201 |
Evaluation and treatment of male and female pattern hair loss. | Journal of the American Academy of Dermatology 20050201 |
Chronic telogen effluvium: a study of 5 patients over 7 years. | Journal of the American Academy of Dermatology 20050201 |
2004 drug approval highlights: FDA update. | The Nurse practitioner 20050201 |
A Korean family of hypokalemic periodic paralysis with mutation in a voltage-gated calcium channel (R1239G). | Journal of Korean medical science 20050201 |
The interaction among sex, hemoglobin and outcomes in a specialty heart failure clinic. | The Canadian journal of cardiology 20050201 |
Is heart rate variability an objective parameter with which to manage treatment of infants with heart failure due to left-to-right shunting? | Cardiology in the young 20050201 |
Clinical implications of an accurate problem list on heart failure treatment. | Journal of general internal medicine 20050201 |
RALES, EPHESUS and redox. | The Journal of steroid biochemistry and molecular biology 20050201 |
Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study. | The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20050201 |
[The 10-minute consultation. Accidental finding: hyperkalemia. Caution with analgesics and bananas]. | MMW Fortschritte der Medizin 20050127 |
[Complications of liver cirrhosis: oesophageal varices, ascites and hepato-cellular carcinoma]. | Revue medicale suisse 20050119 |
Drug safety in patients with heart failure. | Archives of internal medicine 20050110 |
Adult height after ketoconazole treatment in patients with familial male-limited precocious puberty. | The Journal of clinical endocrinology and metabolism 20050101 |
A comparison of in vitro and in vivo EDSTAC test battery results for detecting antiandrogenic activity. | Toxicology and applied pharmacology 20050101 |
Eplerenone: a selective aldosterone receptor antagonist for patients with heart failure. | The Annals of pharmacotherapy 20050101 |
Examination of 209 drugs for inhibition of cytochrome P450 2C8. | Journal of clinical pharmacology 20050101 |
Spironolactone improves lung diffusion in chronic heart failure. | European heart journal 20050101 |
Eplerenone: a review of its use in essential hypertension. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101 |
Aldosterone rapidly activates Na+/H+ exchange in M-1 cortical collecting duct cells via a PKC-MAPK pathway. | Nephron. Physiology 20050101 |
[Advances in therapy for ascites and hepatorenal syndrome]. | Zeitschrift fur Gastroenterologie 20050101 |
Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension. | BMC medical genetics 20050101 |
[Edema in heart disease]. | Nihon rinsho. Japanese journal of clinical medicine 20050101 |
Chemopreventive effect of five drugs on renal interstitial fibrosis induced by an aristolochic acid-containing Chinese herb in rats. | American journal of nephrology 20050101 |
A new selective aldosterone antagonist. Inspra's role in hypertension and post-MI heart failure. | Advance for nurse practitioners 20050101 |
Antiproteinuric effects of mineralocorticoid receptor blockade in patients with chronic renal disease. | American journal of hypertension 20050101 |
Aldosterone-to-renin ratio, arterial stiffness, and the response to aldosterone antagonism in essential hypertension. | American journal of hypertension 20050101 |
Budd-Chiari syndrome. | Mymensingh medical journal : MMJ 20050101 |
Management of heart failure and left ventricular systolic dysfunction following acute myocardial infarction. | Clinical cardiology 20050101 |
[The best of cardiac failure in 2004]. | Archives des maladies du coeur et des vaisseaux 20050101 |
Ahimsa and alternatives -- the concept of the 4th R. The CPCSEA in India. | ALTEX 20050101 |
[Whereabouts of surplus and surviving laboratory animals]. | ALTEX 20050101 |
Use of nonhuman primates in research in Sweden: 25 year longitudinal survey. | ALTEX 20050101 |
Animal vs. non-animal tests for the monitoring of marine biotoxins in the EU. | ALTEX 20050101 |
Mineralocorticoid receptor is overexpressed in cardiomyocytes of patients with congestive heart failure. | Congestive heart failure (Greenwich, Conn.) 20050101 |
A meta-analytical approach to the efficacy of antihypertensive drugs in reducing blood pressure. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101 |
Prevalence of primary hyperaldosteronism assessed by aldosterone/renin ratio and spironolactone testing. | Clinical medicine (London, England) 20050101 |
The 'Statinth' wonder of the world: a panacea for all illnesses or a bubble about to burst. | Journal of negative results in biomedicine 20050101 |
Ask the doctors. I've read that the medication spironolactone may cause cardiac arrest. Please discuss the pros and cons of this medicine. Does The Cleveland Clinic prescribe such a regimen for conditions after heart surgery? | Heart advisor 20050101 |
Diastolic dysfunction and diastolic heart failure: diagnostic, prognostic and therapeutic aspects. | Cardiovascular ultrasound 20050101 |
Spironolactone in the treatment of polycystic ovary syndrome: effects on clinical features, insulin sensitivity and lipid profile. | Journal of endocrinological investigation 20050101 |
Interactions of high salt intake and the response of the cardiovascular system to aldosterone. | Cardiology in review 20050101 |
The effect of agonists and antagonists on Hep-2 cells. | Biomedical sciences instrumentation 20050101 |
Nongenomic effects of mineralocorticoid receptor activation in the cardiovascular system. | Steroids 20050101 |
Cardiovascular effects of aldosterone. | Bratislavske lekarske listy 20050101 |
[Ischemic stroke as reaction to an acute stressful event]. | Medicinski arhiv 20050101 |
Dermatological conditions during TNF-alpha-blocking therapy in patients with rheumatoid arthritis: a prospective study. | Arthritis research & therapy 20050101 |
Idiopathic portal hypertension complicating systemic sclerosis: a case report. | BMC gastroenterology 20050101 |
Pharmacokinetics and pharmacodynamics of mineralocorticoid blocking agents and their effects on potassium homeostasis. | Heart failure reviews 20050101 |
Effects of aldosterone and mineralocorticoid receptor blockade on intracellular electrolytes. | Heart failure reviews 20050101 |
Autonomic effects of spironolactone and MR blockers in heart failure. | Heart failure reviews 20050101 |
Effect of MR blockade on collagen formation and cardiovascular disease with a specific emphasis on heart failure. | Heart failure reviews 20050101 |
The role of aldosterone blockade in patients with heart failure. | Heart failure reviews 20050101 |
Developmental toxicity testing from animal towards embryonic stem cells. | ALTEX 20050101 |
Fourth EU report on the statistics on the number of animals used for scientific purposes in 2002 -- trends, problems, conclusions. | ALTEX 20050101 |
Towards an alternative for the acute fish LC(50) test in chemical assessment: the fish embryo toxicity test goes multi-species -- an update. | ALTEX 20050101 |
Short tandem repeat DNA typing provides an international reference standard for authentication of human cell lines. | ALTEX 20050101 |
[Serological test methods as replacement for infection trials in piglets to test the potency of E. coli vaccines for sows (dams)]. | ALTEX 20050101 |
[EU-Cosmetics: timetables for the replacement of animal experiments]. | ALTEX 20050101 |
Glucocorticoid receptor involvement in pair bonding in female prairie voles: the effects of acute blockade and interactions with central dopamine reward systems. | Neuroscience 20050101 |
Antihypertensive therapy: role of aldosterone antagonists. | Current pharmaceutical design 20050101 |
Cardiac conduction abnormalities and congenital immunodeficiency in a child with Kabuki syndrome: case report. | BMC medical genetics 20050101 |
[Implantation of an extracardiac mesh in the treatment of dilated cardiomyopathy: the TOLK Study (Therapevticheskoe Operativnoe Lechenie Kardiomyopatye)]. | Kardiologiia 20050101 |
Eplerenone reduces oxidative stress and enhances eNOS in SHR: vascular functional and structural consequences. | Antioxidants & redox signaling 20050101 |
Plasma aldosterone to renin ratio predicts treatment response in primary aldosteronism: is volume loading needed? | Blood pressure 20050101 |
Heart failure guidelines and prescribing in primary care across Europe. | BMC health services research 20050101 |
Virtual test kits for predicting harmful effects triggered by drugs and chemicals mediated by specific proteins. | ALTEX 20050101 |
Metabolism of xenobiotics in the incubated hen's egg: investigations with ethyl 4-hydroxybenzoate. | ALTEX 20050101 |
[Animal experiments in biomedical research. An evaluation of the clinical relevance of approved animal experimental projects]. | ALTEX 20050101 |
Evaluation of serum- and animal protein-free media for the production of infectious bronchitis virus (M41) strain in a continuous cell line. | ALTEX 20050101 |
Replacement of the in vivo neutralisation test for efficacy demonstration of tetanus vaccines ad us. vet. | ALTEX 20050101 |
[Olympus cell R: imaging station for life science]. | ALTEX 20050101 |
Prevalence of botulinum neurotoxin C1 and its corresponding gene in environmental samples from low and high risk avian botulism areas. | ALTEX 20050101 |
Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors). | Nuclear receptor 20050101 |
Life-threatening hyperkalemia during a combined therapy with the angiotensin receptor blocker candesartan and spironolactone. | The Kobe journal of medical sciences 20050101 |
[The place of aldosterone receptor blockers in the treatment of chronic heart failure]. | Kardiologiia 20050101 |
[Changing views on the place of loop and thiazide diuretics in the treatment of chronic heart failure. Part II. Influence on outcomes and clinical application]. | Kardiologiia 20050101 |
Eplerenone : a pharmacoeconomic review of its use in patients with post-myocardial infarction heart failure. | PharmacoEconomics 20050101 |
Large artery stiffness and antihypertensive agents. | Current pharmaceutical design 20050101 |
Life-threatening, preventable hyperkalemia in a nursing home resident: case report and literature review. | Journal of the American Medical Directors Association 20050101 |
Polycystic ovary syndrome (PCOS) in the adolescent patient: recommendations for practice. | Pediatric nursing 20050101 |
Strategies to reduce hospitalization in the management of heart failure. | Lippincott's case management : managing the process of patient care 20050101 |
[Man and his fellow-creatures under ethical aspects]. | ALTEX 20050101 |
[The three Rs: looking back ... and forward]. | ALTEX 20050101 |
[The use of transgenic animals in biomedical research in Germany. Part 1: Status Report 2001-2003]. | ALTEX 20050101 |
Reactivation of creatine kinase by dithiothreitol prior to use in an in vitro translation extract. | ALTEX 20050101 |
[Ethics as a scientific basis for animal protection - on the advancement and amendment of the Codex Veterinarius]. | ALTEX 20050101 |
Ukraine and Russia: major InterNICHE outreach. | ALTEX 20050101 |
Diabetes and heart failure: epidemiology, pathophysiology and management. | Indian heart journal 20050101 |
Cardioprotection by aldosterone receptor antagonism in heart failure. Part I. The role of aldosterone in heart failure. | Fiziologiia cheloveka 20050101 |
Aldosterone in heart and kidney diseases. | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101 |
[Late drug-induced hyperkalemia in a patient with congestive heart failure]. | Przeglad lekarski 20050101 |
The diagnosis and management of chronic heart failure in the older patient. | British medical bulletin 20050101 |
[Novel action of aldosterone in CsA nephrotoxicity]. | Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20050101 |
[Castleman disease of the neck]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20050101 |
[Headache in children and adolescent in ambulatory practice]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20050101 |
[Some particular aspects in cases of pleomorphic adenoma of the parotid gland]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20050101 |
[The detection of dysplastic lesions of the gallbladder mucosa in polypoid cholelithiasis]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20050101 |
Automatic detection of spironolactone - related adverse drug events. | AMIA ... Annual Symposium proceedings. AMIA Symposium 20050101 |
[Refractory ascites and dilutional hyponatremia: current management and new aquaretics]. | Revista de gastroenterologia de Mexico 20050101 |
Abstracts to the 5th World Congress 2005 on Alternatives & Animal Use in the Life Sciences. August 21-25, 2005. Berlin, Germany. | ALTEX 20050101 |
Eplerenone: the evidence for its place in the treatment of heart failure after myocardial infarction. | Core evidence 20050101 |
Biventricular pacing (cardiac resynchronization therapy): an evidence-based analysis. | Ontario health technology assessment series 20050101 |
Effect of spironolactone on acid and alkaline phosphatase in the testes of albino rat. | Indian journal of clinical biochemistry : IJCB 20050101 |
Hyperkalemia after the publication of RALES. | The New England journal of medicine 20041202 |
Hyperkalemia after the publication of RALES. | The New England journal of medicine 20041202 |
Hyperkalemia after the publication of RALES. | The New England journal of medicine 20041202 |
Hyperkalemia after the publication of RALES. | The New England journal of medicine 20041202 |
Ventilatory effects of gap junction blockade in the RTN in awake rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20041201 |
Cardiac arrhythmias due to severe hypokalemia in a patient with classic Bartter disease. | Pediatric nephrology (Berlin, Germany) 20041201 |
The neuroendocrine-immune interface gone awry in aldosteronism. | Cardiovascular research 20041201 |
Critical role of CNS effects of aldosterone in cardiac remodeling post-myocardial infarction in rats. | Cardiovascular research 20041201 |
Austrian survey of treating heart failure--AUSTRIA. | European journal of heart failure 20041201 |
Neurohormones and heart failure. | The Nursing clinics of North America 20041201 |
Implementation of guidelines for management of heart failure in heart failure clinic: effects beyond pharmacological treatment. | International journal of cardiology 20041201 |
Eplerenone in hypertension. | Expert opinion on pharmacotherapy 20041201 |
Electropharmacological effects of a spironolactone derivative, potassium canrenoate, assessed in the halothane-anesthetized canine model. | Journal of pharmacological sciences 20041201 |
A patient with concurrent primary hyperaldosteronism and adrenal insufficiency. | The American journal of the medical sciences 20041201 |
Aldosterone directly stimulates cardiac myocyte hypertrophy. | Journal of cardiac failure 20041201 |
Outpatient treatment of systolic heart failure. | American family physician 20041201 |
Aldosterone upregulates connective tissue growth factor gene expression via p38 MAPK pathway and mineralocorticoid receptor in ventricular myocytes. | Journal of Korean medical science 20041201 |
[Clinical characteristics, treatment and short-term morbidity and mortality of patients with heart failure followed in heart failure clinics. Results of the BADAPIC Registry]. | Revista espanola de cardiologia 20041201 |
Spironolactone-induced renal insufficiency and hyperkalemia in patients with heart failure. | American heart journal 20041201 |
Expression and regulation of the sterol half-transporter genes ABCG5 and ABCG8 in rats. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20041201 |
Heart failure drug poses potassium problems. When using 'the water pill' spironolactone, watch your potassium intake and check your levels. | Harvard heart letter : from Harvard Medical School 20041201 |
[Pharmacological therapy of chronic heart failure in the elderly]. | Italian heart journal : official journal of the Italian Federation of Cardiology 20041201 |
Heart failure. | Clinical evidence 20041201 |
Polycystic ovary syndrome. | Clinical evidence 20041201 |
Spironolactone in combination with cilazapril ameliorates proteinuria and renal interstitial fibrosis in rats with anti-Thy-1 irreversible nephritis. | Hypertension research : official journal of the Japanese Society of Hypertension 20041201 |
Aldosterone in heart failure: pathophysiology and treatment. | Current heart failure reports 20041201 |
[Spironolactone and potassium]. | Ugeskrift for laeger 20041122 |
Which inhibitor of the renin-angiotensin system should be used in chronic heart failure and acute myocardial infarction? | Circulation 20041116 |
Effects of adrenomedullin on aldosterone-induced cell proliferation in rat cardiac fibroblasts. | Biochimica et biophysica acta 20041105 |
Mechanisms for aldosterone and spironolactone-induced positive inotropic actions in the rat heart. | Hypertension (Dallas, Tex. : 1979) 20041101 |
Glucocorticoid receptors are involved in the regulation of pulsatile urea excretion in toadfish. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20041101 |
Tolerability of spironolactone in patients with chronic heart failure -- a cautionary message. | British journal of clinical pharmacology 20041101 |
The use of aldosterone receptor blockers in the treatment of hypertension. | Journal of clinical hypertension (Greenwich, Conn.) 20041101 |
Spironolactone does not prevent restenosis after coronary stenting in humans. | Annals of the Academy of Medicine, Singapore 20041101 |
A case of insulin edema with inappropriate hyperaldosteronism. | Journal of endocrinological investigation 20041101 |
Pleiotropic actions of aldosterone and the effects of eplerenone, a selective mineralocorticoid receptor antagonist. | Hypertension research : official journal of the Japanese Society of Hypertension 20041101 |
Effects of AT1 receptor antagonist and spironolactone on cardiac expression of ET-1 mRNA in SHR-SP/Izm. | Journal of cardiovascular pharmacology 20041101 |
Control of vascular changes by renin-angiotensin-aldosterone system in salt-sensitive hypertension. | European journal of pharmacology 20041025 |
[Therapy of heart failure after myocardial infarction. With eplerenone a new course]. | MMW Fortschritte der Medizin 20041021 |
[More benefit in hypertension and high-grade reduction of the pump performance. Earlier beginning of therapy maximizes the benefit]. | MMW Fortschritte der Medizin 20041021 |
Phase II multicentre randomised study of docetaxel plus epirubicin vs 5-fluorouracil plus epirubicin and cyclophosphamide in metastatic breast cancer. | British journal of cancer 20041018 |
Mineralocorticoid receptor antagonism and cardiac remodeling in ischemic heart failure. | Current medicinal chemistry. Cardiovascular and hematological agents 20041001 |
The use of selective aldosterone antagonists. | Current hypertension reports 20041001 |
Effects of adrenomedullin on cell proliferation in rat adventitia induced by aldosterone. | Journal of hypertension 20041001 |
Spironolactone impairs endothelial function and heart rate variability in patients with type 2 diabetes. | Diabetologia 20041001 |
National survey of the prevalence, incidence, primary care burden, and treatment of heart failure in Scotland. | Heart (British Cardiac Society) 20041001 |
Prevention of renal fibrosis by spironolactone in mice with complete unilateral ureteral obstruction. | The Journal of urology 20041001 |
Hirsutism and acne in polycystic ovary syndrome. | Best practice & research. Clinical obstetrics & gynaecology 20041001 |
Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats. | Kidney international 20041001 |
Effect of spironolactone on K(+) homeostasis and ENaC expression in lymphocytes from chronic hemodialysis patients. | Kidney international 20041001 |
Eplerenone, a selective aldosterone blocker, improves diastolic function in aged rats with small-to-moderate myocardial infarction. | Journal of cardiac failure 20041001 |
Cardiac rotation and relaxation in patients with chronic heart failure. | European journal of heart failure 20041001 |
The 'real' woman with heart failure. Impact of sex on current in-hospital management of heart failure by cardiologists and internists. | European journal of heart failure 20041001 |
Differences in the determinants of eplerenone, spironolactone and aldosterone binding to the mineralocorticoid receptor. | Clinical and experimental pharmacology & physiology 20041001 |
High serum prostate-specific antigen concentrations in hirsute women do not decrease with treatment by the combination of spironolactone and the contraceptive pill. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20041001 |
Glucocorticoid-remediable aldosteronism. | Arquivos brasileiros de endocrinologia e metabologia 20041001 |
More on the history of arrhythmia in long QT syndrome. | Journal of the American College of Cardiology 20040915 |
Spironolactone and angiotensin receptor blocker in nondiabetic renal diseases. | The American journal of medicine 20040915 |
[Hyperkalemia and impaired renal function in patients taking spironolactone for congestive heart failure. A retrospective analysis of 125 consecutive cases]. | Ugeskrift for laeger 20040906 |
[Spironolactone inhibits production of proinflammatory cytokines, including tumor necrosis factor-alpha and interferon-gamma and has potential effect in the treatment of arthritis]. | Ugeskrift for laeger 20040906 |
The glucocorticoid receptor antagonist mifepristone reduces ethanol intake in rats under limited access conditions. | Psychoneuroendocrinology 20040901 |
[Angiotensin receptor blockers in heart failure. CHARM Study]. | Der Internist 20040901 |
Novel spironolactone-analogs as impurities in spironolactone. | Steroids 20040901 |
[Androgenetic alopecia]. | Revue medicale de Bruxelles 20040901 |
Aldosterone and anti-aldosterone effects in cardiovascular diseases and diabetic nephropathy. | Diabetes & metabolism 20040901 |
Aldosterone blockade in heart failure. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20040901 |
[Heart failure management: guidelines versus clinical practice]. | Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20040901 |
Clinical profile of contraceptive progestins. | The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20040901 |
[Natriuretic peptides--new diagnostic markers in heart disease]. | Herz 20040901 |
Additive effects of combined valsartan and spironolactone on cardiac aldosterone escape in spontaneously hypertensive rats. | Life sciences 20040827 |
Study warns of danger of combining spironolactone and ACE inhibitors in heart patients. | BMJ (Clinical research ed.) 20040821 |
Mineralocorticoid receptor antagonism prevents the electrical remodeling that precedes cellular hypertrophy after myocardial infarction. | Circulation 20040817 |
Aldosterone modulates neural vasomotor response in hypertension: role of calcitonin gene-related peptide. | Regulatory peptides 20040815 |
Usefulness of spironolactone in a specialized heart failure clinic. | The American journal of cardiology 20040815 |
Treatment of heart failure with spironolactone--trial and tribulations. | The New England journal of medicine 20040805 |
Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study. | The New England journal of medicine 20040805 |
Prognostic value of health status in patients with heart failure after acute myocardial infarction. | Circulation 20040803 |
Effect of aldosterone antagonism on myocardial dysfunction in hypertensive patients with diastolic heart failure. | Circulation 20040803 |
Mineralocorticoid receptor antagonists and hypertension: is there a rationale? | Current hypertension reports 20040801 |
Aldosterone-receptor antagonism and end-stage renal disease. | Current hypertension reports 20040801 |
[Additive improvement of left ventricular remodeling by aldosterone receptor blockade with eplerenone and angiotensin II type 1 receptor antagonist in rats with myocardial infarction]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040801 |
[Mineralocorticoid receptor antagonist spironolactone improves left ventricular remodeling in patients with congestive heart failure and acute myocardial infarction]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040801 |
Rapid effects of aldosterone on vascular cells: clinical implications. | Steroids 20040801 |
The clinical implications of aldosterone escape in congestive heart failure. | European journal of heart failure 20040801 |
Gynecomastia and antihypertensive therapy. | Journal of clinical hypertension (Greenwich, Conn.) 20040801 |
How prevalent is hyperkalemia and renal dysfunction during treatment with spironolactone in patients with congestive heart failure? | Journal of cardiac failure 20040801 |
Hypokalemic quadriparesis with normotensive primary hyperaldosteronism. | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20040801 |
Continuous wavelet transformation applied to the simultaneous quantitative analysis of two-component mixtures. | Die Pharmazie 20040801 |
[Aldosterone]. | Rinsho byori. The Japanese journal of clinical pathology 20040801 |
Aldosterone rapidly activates Src kinase in M-1 cells involving the mineralocorticoid receptor and HSP84. | FEBS letters 20040716 |
[Hyperkalemia. Main symptoms: muscle weakness, cardiac arrhythmias]. | Praxis 20040714 |
Eplerenone, but not steroid withdrawal, reverses cardiac fibrosis in deoxycorticosterone/salt-treated rats. | Endocrinology 20040701 |
Pituitary expression of type I and type II glucocorticoid receptors during chicken embryonic development and their involvement in growth hormone cell differentiation. | Endocrinology 20040701 |
A regulatory role of prolactin, growth hormone, and corticosteroids for human T-cell production of cytokines. | Brain, behavior, and immunity 20040701 |
Eplerenone: will it have a role in the treatment of acute coronary syndromes? | Current cardiology reports 20040701 |
Glucocorticoid-mediated mineralocorticoid receptor activation and hypertension. | Current opinion in nephrology and hypertension 20040701 |
Aldosterone enhances renal calcium reabsorption by two types of channels. | Kidney international 20040701 |
Effects of spironolactone on endothelial function, vascular angiotensin converting enzyme activity, and other prognostic markers in patients with mild heart failure already taking optimal treatment. | Heart (British Cardiac Society) 20040701 |
Life-threatening hyperkalemia in the intraoperative period. | Journal of neurosurgical anesthesiology 20040701 |
Aldosterone antagonism and congestive heart failure: a new look at an old therapy. | Current opinion in cardiology 20040701 |
Inspra improves survival for CHF patients. | The Nurse practitioner 20040701 |
Influence of spironolactone treatment on gentamicin-induced nephrotoxicity in rats. | Basic & clinical pharmacology & toxicology 20040701 |
Efficacy of aldosterone receptor antagonism in heart failure: potential mechanisms. | Current heart failure reports 20040701 |
Impaired endothelium-dependent flow-mediated vasodilation in hypertensive subjects with hyperaldosteronism. | Circulation 20040615 |
Effect of spironolactone on endothelial function in patients with congestive heart failure on conventional medical therapy. | The American journal of cardiology 20040615 |
Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells. | Circulation 20040608 |
Glucocorticoids stimulate cation absorption by semicircular canal duct epithelium via epithelial sodium channel. | American journal of physiology. Renal physiology 20040601 |
Does the type II glucocorticoid receptor mediate cortisol-induced suppression in pituitary responsiveness to gonadotropin-releasing hormone? | Endocrinology 20040601 |
Rats exhibit aldosterone-dependent sodium appetite during 24 h hindlimb unloading. | The Journal of physiology 20040601 |
Eplerenone prevents salt-induced vascular remodeling and cardiac fibrosis in stroke-prone spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20040601 |
Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy. | Hypertension (Dallas, Tex. : 1979) 20040601 |
Aldosterone and aldosterone antagonism in systemic hypertension. | Current hypertension reports 20040601 |
Adding low-dose spironolactone to multidrug regimens for resistant hypertension. | Current hypertension reports 20040601 |
Effect of aldosterone on renal transforming growth factor-beta. | American journal of physiology. Renal physiology 20040601 |
Normal pregnancy outcome following inadvertent exposure to rosiglitazone, gliclazide, and atorvastatin in a diabetic and hypertensive woman. | Reproductive toxicology (Elmsford, N.Y.) 20040601 |
Clinical manifestation of aldosteronoma. | The Surgical clinics of North America 20040601 |
Distinguishing the antihypertensive and electrolyte effects of eplerenone. | The Journal of clinical endocrinology and metabolism 20040601 |
Comparison of efficacy of spironolactone with metformin in the management of polycystic ovary syndrome: an open-labeled study. | The Journal of clinical endocrinology and metabolism 20040601 |
Searching for evidence: Refractory questions in advanced heart failure. | Journal of cardiac failure 20040601 |
Evaluation of high blood pressure in a 12-year-old girl. | Pediatric nephrology (Berlin, Germany) 20040601 |
Racial differences in patients' potassium concentrations during spironolactone therapy for heart failure. | Pharmacotherapy 20040601 |
A mammalian steroid action inhibitor spironolactone retards plant growth by inhibition of brassinosteroid action and induces light-induced gene expression in the dark. | The Journal of steroid biochemistry and molecular biology 20040601 |
[Cardiac failure in Chilean hospitals: results of the National Registry of Heart Failure, ICARO]. | Revista medica de Chile 20040601 |
Eplerenone: a new selective aldosterone receptor antagonist. | Drugs of today (Barcelona, Spain : 1998) 20040601 |
Nuclear envelope: nanoarray responsive to aldosterone. | The Journal of membrane biology 20040601 |
Transient permeability leak of nuclear envelope induced by aldosterone. | The Journal of membrane biology 20040601 |
Heart failure. | Clinical evidence 20040601 |
Cost-effective therapy in patients with idiopathic hirsutism. | Expert review of pharmacoeconomics & outcomes research 20040601 |
Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. | The New England journal of medicine 20040520 |
Effects of ACE gene insertion/deletion polymorphism on response to spironolactone in patients with chronic heart failure. | The American journal of medicine 20040515 |
Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone. | Circulation 20040511 |
Influence of socioeconomic deprivation on the primary care burden and treatment of patients with a diagnosis of heart failure in general practice in Scotland: population based study. | BMJ (Clinical research ed.) 20040508 |
[Primary prevention of sudden cardiac death]. | Deutsche medizinische Wochenschrift (1946) 20040507 |
Human endothelium: target for aldosterone. | Hypertension (Dallas, Tex. : 1979) 20040501 |
The many targets of aldosterone. | Hypertension (Dallas, Tex. : 1979) 20040501 |
The effect of spironolactone, cilazapril and their combination on albuminuria in patients with hypertension and diabetic nephropathy is independent of blood pressure reduction: a randomized controlled study. | Diabetic medicine : a journal of the British Diabetic Association 20040501 |
Aldosterone antagonist facilitates the cardioprotective effects of angiotensin receptor blockers in hypertensive rats. | Journal of hypertension 20040501 |
Early nongenomic events in aldosterone action in renal collecting duct cells: PKCalpha activation, mineralocorticoid receptor phosphorylation, and cross-talk with the genomic response. | Journal of the American Society of Nephrology : JASN 20040501 |
Eplerenone in the treatment of chronic heart failure. | Expert review of cardiovascular therapy 20040501 |
Medical treatment regimens of hirsutism. | Reproductive biomedicine online 20040501 |
Role of aldosterone blockade in managing heart failure: new and emerging treatment options. Introduction. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040501 |
Pathophysiologic role of the renin-angiotensin-aldosterone and sympathetic nervous systems in heart failure. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040501 |
Integrating traditional and emerging treatment options in heart failure. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040501 |
Inhibition of type 2 17beta-hydroxysteroid dehydrogenase by estradiol derivatives bearing a lactone on the D-ring: structure-activity relationships. | Steroids 20040501 |
[Determination of seven residual solvents in spironolactone powder by SPME-HS-GC]. | Se pu = Chinese journal of chromatography 20040501 |
Aldosterone enhances ischemia-induced neovascularization through angiotensin II-dependent pathway. | Circulation 20040427 |
Pharmacological profile of progestins. | Maturitas 20040415 |
Efficacy of eplerenone versus enalapril as monotherapy in systemic hypertension. | The American journal of cardiology 20040415 |
Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20040401 |
Effects of aldosterone receptor antagonist and angiotensin II type I receptor blocker on cardiac transcriptional factors and mRNA expression in rats with myocardial infarction. | Circulation journal : official journal of the Japanese Circulation Society 20040401 |
Spironolactone use in patients with heart failure. | Journal of clinical pharmacy and therapeutics 20040401 |
Efficacy and safety of the selective aldosterone blocker eplerenone in Japanese patients with hypertension: a randomized, double-blind, placebo-controlled, dose-ranging study. | Journal of clinical hypertension (Greenwich, Conn.) 20040401 |
Evolving role of aldosterone blockers alone and in combination with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers in hypertension management: a review of mechanistic and clinical data. | American heart journal 20040401 |
Drug therapy in chronic heart failure. | Postgraduate medical journal 20040401 |
Digitalis for treatment of congestive heart failure in patients in sinus rhythm: a systematic review and meta-analysis. | Journal of cardiac failure 20040401 |
Enhancing oral contraceptive success: the potential of new formulations. | American journal of obstetrics and gynecology 20040401 |
Acquired hemophilia as first manifestation of breast carcinoma in a man under long-term spironolactone therapy. | International journal of clinical oncology 20040401 |
Aldosterone stimulates gene expression of hepatic gluconeogenic enzymes through the glucocorticoid receptor in a manner independent of the protein kinase B cascade. | Endocrine journal 20040401 |
Spironolactone + ace inhibitor or sartan: risk of hyperkalaemia. | Prescrire international 20040401 |
Primary hyperparathyroidism associatiated with aldosterone-producing adrenocortical adenoma and breast cancer: relation to MEN1 gene. | Internal medicine (Tokyo, Japan) 20040401 |
[Proposed protocol for the ambulatory management of patients discharged with heart failure diagnosis: collaborative project Venice-HF]. | Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20040401 |
[A comprehensive management system for heart failure improves clinical outcomes and reduces medical resource utilization]. | Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20040401 |
[A brief history of diagnosis and treatment of primary aldosteronism.]. | Zhonghua yi shi za zhi (Beijing, China : 1980) 20040401 |
Eplerenone (Inspra), a new aldosterone antagonist for the treatment of systemic hypertension and heart failure. | Proceedings (Baylor University. Medical Center) 20040401 |
The discovery, isolation and identification of aldosterone: reflections on emerging regulation and function. | Molecular and cellular endocrinology 20040331 |
The evolution of aldosterone antagonists. | Molecular and cellular endocrinology 20040331 |
The 45-year story of the development of an anti-aldosterone more specific than spironolactone. | Molecular and cellular endocrinology 20040331 |
Effect of aldosterone blockade in patients with systolic left ventricular dysfunction: implications of the RALES and EPHESUS studies. | Molecular and cellular endocrinology 20040331 |
Towards selectively modulating mineralocorticoid receptor function: lessons from other systems. | Molecular and cellular endocrinology 20040331 |
The myosin binding protein is a novel mineralocorticoid receptor binding partner. | Molecular and cellular endocrinology 20040331 |
Aldosterone target organ protection by eplerenone. | Molecular and cellular endocrinology 20040331 |
[Guideline 'Chronic heart failure']. | Nederlands tijdschrift voor geneeskunde 20040327 |
Aldosterone, through novel signaling proteins, is a fundamental molecular bridge between the genetic defect and the cardiac phenotype of hypertrophic cardiomyopathy. | Circulation 20040316 |
[Idiopathic hypereosinophilia with cardiac involvement]. | Deutsche medizinische Wochenschrift (1946) 20040312 |
Selection of patients for heart transplantation in the current era of heart failure therapy. | Journal of the American College of Cardiology 20040303 |
Aldosterone decreases UT-A1 urea transporter expression via the mineralocorticoid receptor. | Journal of the American Society of Nephrology : JASN 20040301 |
Transcardiac increase in tumor necrosis factor-alpha and left ventricular end-diastolic volume in patients with dilated cardiomyopathy. | European journal of heart failure 20040301 |
Pharmacological treatment in patients with heart failure: patients knowledge and occurrence of polypharmacy, alternative medicine and immunizations. | European journal of heart failure 20040301 |
Review of aldosterone- and angiotensin II-induced target organ damage and prevention. | Cardiovascular research 20040301 |
[Significance of aldosterone antagonist therapy]. | Der Internist 20040301 |
Spironolactone for the treatment of isolated systolic hypertension. | American journal of hypertension 20040301 |
A comparison between spironolactone and spironolactone plus finasteride in the treatment of hirsutism. | European journal of endocrinology 20040301 |
The resurrection of spironolactone on its golden anniversary. | American journal of critical care : an official publication, American Association of Critical-Care Nurses 20040301 |
New therapies for heart failure. | RN 20040301 |
Life-threatening hypokalemia in an asthmatic patient treated with high-dose hydrocortisone. | The American journal of the medical sciences 20040301 |
Aldosterone and cardiovascular remodelling: focus on myocardial failure. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20040301 |
Role of the selective aldosterone receptor blockers in arterial hypertension. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20040301 |
[Age-related specifics of aldosterone reception in distal segments of the rat nephrons and of Na(+), K(+)-ATPase expression induction]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20040301 |
[Involvement of Aldosterone and mineralocorticoid receptor in pathogenesis of cardiovascular diseases]. | Nihon rinsho. Japanese journal of clinical medicine 20040301 |
Ask the doctors. I read about a new drug for heart failure called eplerenone. How does it work? Is it safe? | Heart advisor 20040301 |
Prediction of in vivo drug interactions with eplerenone in man from in vitro metabolic inhibition data. | Xenobiotica; the fate of foreign compounds in biological systems 20040301 |
Current concepts in the management of heart failure. | Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20040301 |
[Rhinorrhea as side-effect of spironolactone]. | Atencion primaria 20040227 |
Polymorphism in generic drug product development. | Advanced drug delivery reviews 20040223 |
Comparison of the Hershberger assay and androgen receptor binding assay of twelve chemicals. | Toxicology 20040215 |
Eplerenone (Inspra) for hypertension. | American family physician 20040215 |
Spironolactone inhibits production of proinflammatory cytokines by human mononuclear cells. | Immunology letters 20040215 |
Aldosterone enhances renin gene expression in juxtaglomerular cells. | American journal of physiology. Renal physiology 20040201 |
Undertreatment of congestive heart failure in an Australian setting. | Journal of clinical pharmacy and therapeutics 20040201 |
Aldosterone antagonism and arterial stiffness. | Hypertension (Dallas, Tex. : 1979) 20040201 |
Role of a selective aldosterone blocker in mice with chronic heart failure. | Journal of cardiac failure 20040201 |
The treatment of polycystic ovary syndrome. | Minerva ginecologica 20040201 |
Physician opinions on the implementation of the SIGN guideline for heart failure. | Scottish medical journal 20040201 |
Hair loss remedies--separating fact from fiction. | Cutis 20040201 |
[Immediate administration of mineralocorticoid receptor antagonist spironolactone prevents post-infarct left ventricular remodeling associated with suppression of a marker of myocardial collagen synthesis in patients with first anterior acute myocardial infarction]. | Journal of cardiology 20040201 |
The complex world of prescribing behavior. | JAMA 20040107 |
Effects of pH and the presence of micelles on the resolution of diuretics by reversed-phase liquid chromatography. | Journal of chromatography. A 20040102 |
Distinction between Liddle syndrome and apparent mineralocorticoid excess. | Pediatric nephrology (Berlin, Germany) 20040101 |
Aldosterone antagonism attenuates obesity-induced hypertension and glomerular hyperfiltration. | Hypertension (Dallas, Tex. : 1979) 20040101 |
Glucocorticoids decrease GTP cyclohydrolase and tetrahydrobiopterin-dependent vasorelaxation through glucocorticoid receptors. | Journal of cardiovascular pharmacology 20040101 |
Polycystic ovary syndrome. | Obstetrics and gynecology 20040101 |
Effects of eplerenone on heart and kidney in two-kidney, one-clip rats. | American journal of nephrology 20040101 |
[Benefits of candesartan in the treatment of symptomatic heart failure--CHARM programme]. | Nihon rinsho. Japanese journal of clinical medicine 20040101 |
A review of heart failure treatment. | The Mount Sinai journal of medicine, New York 20040101 |
Smoke induced changes in epithelial cell gene expression: development of an in vitro model for COPD. | ALTEX 20040101 |
Avoidance of animal experiments in the new EU Chemicals Regulation - opportunities and problems from the point of view of animal welfare. | ALTEX 20040101 |
Trends in improving the embryonic stem cell test (EST): an overview. | ALTEX 20040101 |
[About animal experiments for a face without wrinkles]. | ALTEX 20040101 |
Neurohumoral stimulation in type-2-diabetes as an emerging disease concept. | Cardiovascular diabetology 20040101 |
Aldosterone antagonism ameliorates proteinuria and nephrosclerosis independent of glomerular dynamics in L-NAME/SHR model. | American journal of nephrology 20040101 |
The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade. | Expert review of cardiovascular therapy 20040101 |
Drug-induced eosinophilia and multisystemic failure with positive patch-test reaction to spironolactone: DRESS syndrome. | Acta dermato-venereologica 20040101 |
Replacement and refinement of animal experimentation in drug research has been and will be a permanent and necessary process. | ALTEX 20040101 |
Induction, expression and maintenance of cytochrome P450 isoforms in long-term cultures of primary human hepatocytes. | ALTEX 20040101 |
Development of an in vitro model for vascular injury with human endothelial cells. | ALTEX 20040101 |
Endocrine toxicology--contributions of in vitro methods to the 3R concept. | ALTEX 20040101 |
[Toxicoproteomics: first experiences in a BMBF-study]. | ALTEX 20040101 |
Neurotoxicity of active compounds--establishment of hESC-lines and proteomics technologies for human embryo- and neurotoxicity screening and biomarker identification. | ALTEX 20040101 |
Ischemia reperfusion injury in the isolated hemoperfused bovine uterus--a model for the investigation of anti-inflammatory substances? | ALTEX 20040101 |
Validation of cell culture models for the intestine and the blood-brain barrier and comparison of drug permeation. | ALTEX 20040101 |
Quality assurance of C. perfringens epsilon toxoid vaccines--ELISA versus mouse neutralisation test. | ALTEX 20040101 |
[Chips instead of mice: cells on bioelectronic sensor-chips as an alternative to animal experiments]. | ALTEX 20040101 |
[1D-and 3D- computer simulation for experimental planning and interpretation of pharmacokinetic studies in the inner ear after local drug delivery]. | ALTEX 20040101 |
Association between the number of coadministered P-glycoprotein inhibitors and serum digoxin levels in patients on therapeutic drug monitoring. | BMC medicine 20040101 |
(-)-nicotine ameliorates corticosterone's potentiation of N-methyl-d-aspartate receptor-mediated cornu ammonis 1 toxicity. | Neuroscience 20040101 |
Review: spironolactone may be effective for hirsutism but data are lacking on its effectiveness for acne vulgaris in women. | ACP journal club 20040101 |
Assessing the impact of heart failure specialist services on patient populations. | BMC health services research 20040101 |
The role of aldosterone and aldosterone-receptor antagonists in heart failure. | Reviews in cardiovascular medicine 20040101 |
Assessment of a new cell culture perfusion apparatus for in vitro chronic toxicity testing. Part 1: technical description. | ALTEX 20040101 |
Assessment of a new cell culture perfusion apparatus for in vitro chronic toxicity testing. Part 2: toxicological evaluation. | ALTEX 20040101 |
Culturing cells without serum: lessons learnt using molecules of plant origin. | ALTEX 20040101 |
[Animal experiments in the context of quality control of pharmaceuticals. Review of the European Pharmacopoeia, 4th edition, 2002]. | ALTEX 20040101 |
[Vaccine testing without animal experiments?]. | ALTEX 20040101 |
Adrenal aldosterone biosynthesis is elevated in a model of chronic renal failure--role of local adrenal renin-angiotensin system. | Nephron. Physiology 20040101 |
Co-secretion of aldosterone and cortisol by an adrenocortical carcinoma. | Hormone research 20040101 |
Animal use in higher education in the SEE (South Eastern Europe) region. | ALTEX 20040101 |
Optimisation of the EpiDerm test protocol for the upcoming ECVAM validation study on in vitro skin irritation tests. | ALTEX 20040101 |
Report and recommendations of the international workshop 'Retrieval approaches for information on alternative methods to animal experiments'. | ALTEX 20040101 |
Comparison of human corneal cell cultures in cytotoxicity testing. | ALTEX 20040101 |
[Polyurethane vessels for microvascular surgical training to reduce animal use]. | ALTEX 20040101 |
[New potentialities in the treatment of idiopathic hyperaldosteronism]. | Klinicheskaia meditsina 20040101 |
New progestogens: a review of their effects in perimenopausal and postmenopausal women. | Drugs & aging 20040101 |
[Animal research trends in the specific production of basic research]. | ALTEX 20040101 |
[Animal research statistics in 2003 are slightly smaller--a basis for joy?]. | ALTEX 20040101 |
Eplerenone: selective aldosterone antagonism in management of cardiovascular and renal disease. | Journal of the American Pharmacists Association : JAPhA 20040101 |
New treatment option for heart failure patients: eplerenone. | The Journal of cardiovascular nursing 20040101 |
Up to date in pharmacological treatment of dilated cardiomyopathy. | Romanian journal of internal medicine = Revue roumaine de medecine interne 20040101 |
Eplerenone : a review of its use in left ventricular systolic dysfunction and heart failure after acute myocardial infarction. | Drugs 20040101 |
Outcome of patients undergoing laparoscopic adrenalectomy for primary hyperaldosteronism. | JSLS : Journal of the Society of Laparoendoscopic Surgeons 20040101 |
[Man and his fellow-creatures under ethical aspects]. | ALTEX 20040101 |
[Animal testing ethics and human testing. Thoughts on our conduct with and our relationship to animals]. | ALTEX 20040101 |
[A new in vitro model to quantify angiogenesis]. | ALTEX 20040101 |
Alternatives to animal experimentation in basic research. | ALTEX 20040101 |
Alternatives to animal experimentation in biomedical education. | ALTEX 20040101 |
Audit of therapeutic interventions in inpatient children using two scores: are they evidence-based in developing countries? | BMC health services research 20040101 |
Thyrotoxic periodic paralysis: an overview. | Annals of Saudi medicine 20040101 |
[Tendencies and results in rectal cancer treatment]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20040101 |
[Aspects of the children's candidiasis in outpatient practice]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20040101 |
Practical approach to the hormonal treatment of acne. | Journal of cutaneous medicine and surgery 20040101 |
Hormonal treatment of acne: review of current best evidence. | Journal of cutaneous medicine and surgery 20040101 |
Hormonal therapy of acne. | Journal of cutaneous medicine and surgery 20040101 |
Hormonal approach to the treatment of acne a Canadian perspective. | Journal of cutaneous medicine and surgery 20040101 |
[Surgical treatment of Graves' disease]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20040101 |
Interface flow process audit: using the patient's career as a tracer of quality of care and of system organisation. | International journal of integrated care 20040101 |
Rapid inhibition of vasoconstriction in renal afferent arterioles by aldosterone. | Circulation research 20031212 |
Classification and pharmacology of progestins. | Maturitas 20031210 |
Aldosterone increases NHE-1 expression and induces NHE-1-dependent hypertrophy in neonatal rat ventricular myocytes. | Hypertension (Dallas, Tex. : 1979) 20031201 |
Mineralocorticoids act centrally to regulate blood-borne tumor necrosis factor-alpha in normal rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20031201 |
The role of mineralocorticoid receptor antagonists in the treatment of cardiac failure. | Expert opinion on investigational drugs 20031201 |
Determinants of spironolactone binding specificity in the mineralocorticoid receptor. | Journal of molecular endocrinology 20031201 |
Endothelial cell swelling by aldosterone. | The Journal of membrane biology 20031201 |
[Is early discharge possible in patients with uncomplicated heart failure? Cost-efficacy analysis]. | Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20031201 |
Hyperaldosteronism and pheochromocytoma: new tricks and tests. | Primary care 20031201 |
Budd-Chiari syndrome in a young patient with celiac sprue: a case report. | The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20031201 |
[Aldosterone receptor antagonists in heart failure. Rightly brought back from retirement]. | MMW Fortschritte der Medizin 20031120 |
A new oral therapy for long QT syndrome: long-term oral potassium improves repolarization in patients with HERG mutations. | Journal of the American College of Cardiology 20031119 |
Aldosterone and not plasminogen activator inhibitor-1 is a critical mediator of early angiotensin II/NG-nitro-L-arginine methyl ester-induced myocardial injury. | Circulation 20031118 |
Hyperkalaemia and impaired renal function in patients taking spironolactone for congestive heart failure: retrospective study. | BMJ (Clinical research ed.) 20031115 |
The CHARM programme. | Lancet (London, England) 20031115 |
Aldosteronism and peripheral blood mononuclear cell activation: a neuroendocrine-immune interface. | Circulation research 20031114 |
[Production of aldosterone by rat mesangial cell and the accumulation of extracellular matrix induced by aldosterone]. | Zhonghua yi xue za zhi 20031110 |
Additive improvement of left ventricular remodeling and neurohormonal activation by aldosterone receptor blockade with eplerenone and ACE inhibition in rats with myocardial infarction. | Journal of the American College of Cardiology 20031105 |
Aldosterone antagonism and myocardial infarction: from animals to man and back. | Journal of the American College of Cardiology 20031105 |
Distinct responses of membranoproliferative glomerulonephritis-related proteinuria to spironolactone with and without angiotensin II blockade. | Annals of internal medicine 20031104 |
Aldosterone potentiates 1,25-dihydroxyvitamin D3 action in renal thick ascending limb via a nongenomic, ERK-dependent pathway. | American journal of physiology. Cell physiology 20031101 |
Interactions of diazoxide with frusemide, spironolactone, and acetylsalicylic acid in a patient with hyperinsulinism of Infancy and Fallot tetralogy. | European journal of pediatrics 20031101 |
Can renin status predict the antihypertensive efficacy of eplerenone add-on therapy? | Journal of clinical pharmacology 20031101 |
Safety of low-dose spironolactone administration in chronic haemodialysis patients. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20031101 |
Is spironolactone safe for dialysis patients? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20031101 |
Pharmacokinetics and metabolism of [14C]eplerenone after oral administration to humans. | Drug metabolism and disposition: the biological fate of chemicals 20031101 |
Spectophotometric quantitative resolution of hydrochlorothiazide and spironolactone in tablets by chemometric analysis methods. | Farmaco (Societa chimica italiana : 1989) 20031101 |
Efficacy of low-dose spironolactone in subjects with resistant hypertension. | American journal of hypertension 20031101 |
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients. | Journal of hypertension 20031101 |
Ethacrynic acid can be effective for refractory congestive heart failure and ascites. | Southern medical journal 20031101 |
Androgens and antiandrogens. | Annals of the New York Academy of Sciences 20031101 |
Drug therapy in chronic heart failure. | Postgraduate medical journal 20031101 |
Spironolactone-induced agranulocytosis: a case report. | The Kaohsiung journal of medical sciences 20031101 |
Conception and pharmacodynamic profile of drospirenone. | Steroids 20031101 |
Corticosteroid effect on Caco-2 cell lipids depends on cell differentiation. | The Journal of steroid biochemistry and molecular biology 20031101 |
The cardiovascular effects of eplerenone, a selective aldosterone-receptor antagonist. | Clinical therapeutics 20031101 |
Avoid the risks of mixed medications. How to minimize dangerous interactions with cardiovascular drugs. | Heart advisor 20031101 |
Aldosterone stimulates epidermal growth factor receptor expression. | The Journal of biological chemistry 20031031 |
[Selective aldosterone blocking in heart failure. Eplerenone reduces the risk after infarction]. | MMW Fortschritte der Medizin 20031030 |
[Effects of aldosterone and spironolactone on the proliferation and collagen synthesis of hepatic stellate cells in rats]. | Zhonghua yi xue za zhi 20031025 |
Update on therapy for heart failure. | The American journal of medicine 20031015 |
Synergy between publication and promotion: comparing adoption of new evidence in Canada and the United States. | The American journal of medicine 20031015 |
Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy: the 4E-left ventricular hypertrophy study. | Circulation 20031014 |
Aldosterone blockade in patients with systolic left ventricular dysfunction. | Circulation 20031014 |
Two better than one. | Circulation 20031014 |
Diabetes may be independent risk factor for hyperkalaemia. | BMJ (Clinical research ed.) 20031004 |
RAAS escape: a real clinical entity that may be important in the progression of cardiovascular and renal disease. | Current hypertension reports 20031001 |
Early aldosterone up-regulated genes: new pathways for renal disease? | Kidney international 20031001 |
Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis. | Clinical and experimental immunology 20031001 |
Aldosterone receptor blockade and the role of eplerenone: evolving perspectives. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20031001 |
Primary aldosteronism, diagnosed by the aldosterone to renin ratio, is a common cause of hypertension. | Clinical endocrinology 20031001 |
Spironolactone prevents cardiac collagen proliferation after myocardial infarction in rats. | Clinical and experimental pharmacology & physiology 20031001 |
[Respiratory infections outside the hospital. DIRA study]. | Enfermedades infecciosas y microbiologia clinica 20031001 |
Effects of a beta blocker and spironolactone on plasma homocysteine levels. | International journal of cardiology 20031001 |
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. | Chemical research in toxicology 20031001 |
The effect of the maze procedure on the secretion of arginine-vasopressin and aldosterone. | The Journal of thoracic and cardiovascular surgery 20031001 |
Ask the doctor. I am a 50-year-old man with congestive heart failure. My doctor has me on all the usual drugs, and a couple of years ago added spironolactone. I did okay with it for a while, but then began to notice that my breasts were getting bigger and began to hurt. My doctor agreed that I should stop taking spironolactone, but I wonder if I am missing out on something. | Harvard heart letter : from Harvard Medical School 20031001 |
The African-American Heart Failure Trial (A-HeFT): rationale and methodology. | Journal of cardiac failure 20031001 |
The effects of the loop diuretics furosemide and torasemide on diuresis in dogs and cats. | The Journal of veterinary medical science 20031001 |
Anaesthesia for a girl with severe hypertension due to 11 beta-hydroxylase deficiency. | Anaesthesia and intensive care 20031001 |
[Massive unilateral hydrothorax as clinical manifestation of decompensated liver cirrhosis without ascites]. | Praxis 20030910 |
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. | Lancet (London, England) 20030906 |
Aldosterone blockade after myocardial infarction. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030902 |
Hyperkalaemia in congestive heart failure patients using ACE inhibitors and spironolactone. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030901 |
Nongenomic vascular action of aldosterone in the glomerular microcirculation. | Journal of the American Society of Nephrology : JASN 20030901 |
Should the aldosterone-receptor antagonist - eplerenone - be used after acute myocardial infarction with left ventricular dysfunction? | Expert opinion on pharmacotherapy 20030901 |
Efficacy of screening for primary aldosteronism by adrenocortical scintigraphy without discontinuing antihypertensive medication. | American journal of hypertension 20030901 |
Use of nonantiarrhythmic drugs for prevention of sudden cardiac death. | Journal of cardiovascular electrophysiology 20030901 |
Congestive heart failure: guidelines for the primary care physician. | The Mount Sinai journal of medicine, New York 20030901 |
New developments in the management of hypertension. | American family physician 20030901 |
Primary hyperaldosteronism. | Annals of clinical biochemistry 20030901 |
Association of Bartter's syndrome and empty sella. | Journal of pediatric endocrinology & metabolism : JPEM 20030901 |
Role of intracardiac renin-angiotensin-aldosterone system in extracellular matrix remodeling. | Methods and findings in experimental and clinical pharmacology 20030901 |
Effects of spironolactone and metoprolol on QT dispersion in heart failure. | Japanese heart journal 20030901 |
Long-term safety and efficacy of the selective aldosterone blocker eplerenone in patients with essential hypertension. | Clinical therapeutics 20030901 |
Mineralocorticoid receptor blockade: new insights into the mechanism of action in patients with cardiovascular disease. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20030901 |
Potential beneficial as well as detrimental effects of chronic treatment with lisinopril and (or) spironolactone on isolated hearts following low-flow ischemia in normal and infarcted rats. | Canadian journal of physiology and pharmacology 20030901 |
Sparing a little may save a lot: lessons from the Studies of Left Ventricular Dysfunction (SOLVD). | Journal of the American College of Cardiology 20030820 |
[Primary hyperaldosteronism]. | Nederlands tijdschrift voor geneeskunde 20030816 |
Aldosterone blockade and vascular calcification in hemodialysis patients. | The American journal of medicine 20030815 |
Spironolactone alone or in combination with furosemide in the treatment of moderate ascites in nonazotemic cirrhosis. A randomized comparative study of efficacy and safety. | Journal of hepatology 20030801 |
Selective aldosterone blockade with eplerenone in patients with congestive heart failure. | Expert opinion on investigational drugs 20030801 |
A new turbidometric digoxin immunoassay on the ADVIA 1650 analyzer is free from interference by spironolactone, potassium canrenoate, and their common metabolite canrenone. | Therapeutic drug monitoring 20030801 |
'Lack of clinically significant interference by spironolactone with the Axsym Digoxin II assay' only applies to low-dose therapy with spironolactone. | Therapeutic drug monitoring 20030801 |
Most hospitalized older persons do not meet the enrollment criteria for clinical trials in heart failure. | American heart journal 20030801 |
A review of treatment of premenstrual syndrome and premenstrual dysphoric disorder. | Psychoneuroendocrinology 20030801 |
Stimulation of protein degradation by low pH in L6G8C5 skeletal muscle cells is independent of apoptosis but dependent on differentiation state. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030801 |
Selective aldosterone blockade reduces mortality after MI. | The Journal of family practice 20030801 |
The safety of spironolactone treatment in patients with heart failure. | Journal of clinical pharmacy and therapeutics 20030801 |
Primary aldosteronism - treatment options. | Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20030801 |
Effect of combined AT1 receptor and aldosterone receptor antagonism on plasminogen activator inhibitor-1. | The Journal of clinical endocrinology and metabolism 20030801 |
Management of chronic heart failure due to systolic left ventricular dysfunction by cardiologist and non-cardiologist physicians. | European journal of heart failure 20030801 |
Effects of the addition of a low dose of spironolactone on brain natriuretic peptide plasma level and cardiopulmonary function in patients with moderate congestive heart failure. | Medical science monitor : international medical journal of experimental and clinical research 20030801 |
Sialic acid 9-O-acetylesterase catalyzes the hydrolyzing reaction from alacepril to deacetylalacepril. | Pharmaceutical research 20030801 |
Aldosterone receptor antagonists in the treatment of heart failure. | Connecticut medicine 20030801 |
[External electrical cardioversion of atrial arrhythmia: predictive criteria of success]. | Annales de cardiologie et d'angeiologie 20030801 |
Aldosterone receptor antagonists: biology and novel therapeutical applications. | Journal of endocrinological investigation 20030801 |
Potential antiapoptotic activity of aldosterone antagonists in postinfarction remodeling. | Circulation 20030729 |
Interaction of spironolactone with ACE inhibitors or angiotensin receptor blockers: analysis of 44 cases. | BMJ (Clinical research ed.) 20030719 |
Symptoms and the distress they cause: comparison of an aldosterone antagonist and a calcium channel blocking agent in patients with systolic hypertension. | Archives of internal medicine 20030714 |
Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure. | Circulation research 20030711 |
Eplerenone in patients with left ventricular dysfunction. | The New England journal of medicine 20030703 |
Eplerenone in patients with left ventricular dysfunction. | The New England journal of medicine 20030703 |
Eplerenone in patients with left ventricular dysfunction. | The New England journal of medicine 20030703 |
Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling. | Hypertension (Dallas, Tex. : 1979) 20030701 |
Obese Zucker rats have reduced mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type 1 expression in hippocampus-implications for dysregulation of the hypothalamic-pituitary-adrenal axis in obesity. | Endocrinology 20030701 |
Effect of spironolactone on the expression of rat hepatic UDP-glucuronosyltransferase. | Biochemical pharmacology 20030701 |
Pathologic quiz case: an adrenal mass in a 54-year-old man. | Archives of pathology & laboratory medicine 20030701 |
The management of ascites in cirrhosis: report on the consensus conference of the International Ascites Club. | Hepatology (Baltimore, Md.) 20030701 |
Assessment of the novel selective aldosterone blocker eplerenone using ambulatory and clinical blood pressure in patients with systemic hypertension. | The American journal of cardiology 20030701 |
Factors predicting hyperkalemia in patients with cirrhosis receiving spironolactone. | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20030701 |
[Treatment of acne with antiandrogens--an evidence-based review]. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20030701 |
Pharmacotherapy for heart failure in patients with renal insufficiency. | Annals of internal medicine 20030603 |
Pathophysiology and management of pediatric ascites. | Current gastroenterology reports 20030601 |
Aldactone therapy in a peritoneal dialysis patient. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030601 |
Aldactone therapy in a peritoneal dialysis patient. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030601 |
Combined effects of low-dose oral spironolactone and captopril therapy in a rat model of spontaneous hypertension and heart failure. | Journal of cardiovascular pharmacology 20030601 |
Effect of eplerenone, a selective aldosterone blocker, on blood pressure, serum and macrophage oxidative stress, and atherosclerosis in apolipoprotein E-deficient mice. | Journal of cardiovascular pharmacology 20030601 |
Inhibition of platelet activation in congestive heart failure by aldosterone receptor antagonism and ACE inhibition. | Thrombosis and haemostasis 20030601 |
Aldosterone resurgens--letter from EPHESUS. | The Journal of clinical endocrinology and metabolism 20030601 |
Aldosterone receptor blockade improves left ventricular remodeling and increases ventricular fibrillation threshold in experimental heart failure. | Cardiovascular research 20030601 |
Addition of the selective aldosterone receptor antagonist eplerenone to ACE inhibition in heart failure: effect on endothelial dysfunction. | Cardiovascular research 20030601 |
Review of surgical management of aldosterone secreting tumours of the adrenal cortex. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20030601 |
Clinical features and contemporary management of patients with low and preserved ejection fraction heart failure: baseline characteristics of patients in the Candesartan in Heart failure-Assessment of Reduction in Mortality and morbidity (CHARM) programme. | European journal of heart failure 20030601 |
Differences between general practitioners and cardiologists in diagnosis and management of heart failure: a survey in every-day practice. | European journal of heart failure 20030601 |
Update of clinical trials from the American College of Cardiology 2003. EPHESUS, SPORTIF-III, ASCOT, COMPANION, UK-PACE and T-wave alternans. | European journal of heart failure 20030601 |
Trends in prescribing for heart failure in Dutch primary care from 1996 to 2000. | Pharmacoepidemiology and drug safety 20030601 |
Late breaking heart failure trials from the 2003 ACC meeting: EPHESUS and COMPANION. | Journal of cardiac failure 20030601 |
Variable temperature X-ray powder diffractometry of spironolactone polymorphs. | Die Pharmazie 20030601 |
[A case of hypokalemic periodic paralysis: utility of exercise test for the assessment of therapeutic efficacy]. | No to shinkei = Brain and nerve 20030601 |
The suitability of disintegrating force kinetics for studying the effect of manufacturing parameters on spironolactone tablet properties. | AAPS PharmSciTech 20030601 |
Aldosterone regulation of T-type calcium channels. | The Journal of steroid biochemistry and molecular biology 20030601 |
Immediate administration of mineralocorticoid receptor antagonist spironolactone prevents post-infarct left ventricular remodeling associated with suppression of a marker of myocardial collagen synthesis in patients with first anterior acute myocardial infarction. | Circulation 20030527 |
Aldosterone blockade in patients with acute myocardial infarction. | Circulation 20030527 |
Use of spironolactone in heart failure patients receiving angiotensin-converting enzyme inhibitors and beta-blockers. | Journal of the American College of Cardiology 20030521 |
Eplerenone: cardiovascular protection. | Circulation 20030520 |
Eplerenone (Inspra). | The Medical letter on drugs and therapeutics 20030512 |
Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations. | The American journal of cardiology 20030508 |
Aldosterone regulates the Na-K-2Cl cotransporter in vascular smooth muscle. | Hypertension (Dallas, Tex. : 1979) 20030501 |
Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats. | Kidney international 20030501 |
Long-term regulation of ENaC expression in kidney by angiotensin II. | Hypertension (Dallas, Tex. : 1979) 20030501 |
Effects of the selective aldosterone blocker eplerenone versus the calcium antagonist amlodipine in systolic hypertension. | Hypertension (Dallas, Tex. : 1979) 20030501 |
Aldosterone inhibits inducible nitric oxide synthase in neonatal rat cardiomyocytes. | Endocrinology 20030501 |
Expression and modulation of steroidogenic acute regulatory protein messenger ribonucleic acid in rat cardiocytes and after myocardial infarction. | Endocrinology 20030501 |
Regioselective synthesis of the tricyclic core of lateriflorone. | Organic letters 20030501 |
Studies on the interactions between drug and estrogen. II. On the inhibitory effect of 29 drugs reported to induce gynecomastia on the oxidation of estradiol at C-2 or C-17. | Biological & pharmaceutical bulletin 20030501 |
The evaluation and management of hirsutism. | Obstetrics and gynecology 20030501 |
More hope for heart failure. Findings suggest expanded use of aldosterone-blockers. | Health news (Waltham, Mass.) 20030501 |
[Ischemic heart failure]. | Nihon rinsho. Japanese journal of clinical medicine 20030501 |
Aldosterone antagonism and hypertension. | Clinical cardiology 20030501 |
Working heart function in diabetes is not improved by spironolactone treatment. | Canadian journal of physiology and pharmacology 20030501 |
Investigating mineralocorticoid hypertension. | Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20030501 |
Development and validation of a liquid chromatography-tandem mass spectrometric assay for Eplerenone and its hydrolyzed metabolite in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030425 |
[Which patient needs an aldosterone antagonist?]. | MMW Fortschritte der Medizin 20030417 |
Effect of high-dose spironolactone on protein-losing enteropathy in patients with Fontan palliation of complex congenital heart disease. | The American journal of cardiology 20030415 |
Aldosterone blockade and heart failure. | The New England journal of medicine 20030403 |
Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. | The New England journal of medicine 20030403 |
Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients. | Journal of the American College of Cardiology 20030402 |
Hypertension, angiotensin II, aldosterone, and race. | Journal of the American College of Cardiology 20030402 |
Hypovolemia and MSNA discharge patterns: assessing and interpreting sympathetic responses. | American journal of physiology. Heart and circulatory physiology 20030401 |
Nongenomic effect of aldosterone on Na+,K+-adenosine triphosphatase in arterial vessels. | Endocrinology 20030401 |
The effect of aldosterone on glucose metabolism. | Current hypertension reports 20030401 |
Novel yeast bioassay system for detection of androgenic and antiandrogenic compounds. | Toxicology in vitro : an international journal published in association with BIBRA 20030401 |
Serum- and glucocorticoid-regulated kinase isoform-1 and epithelial sodium channel subunits in human ocular ciliary epithelium. | Investigative ophthalmology & visual science 20030401 |
Amiloride reduces stroke and renalinjury in stroke-prone hypertensive rats. | American journal of hypertension 20030401 |
Prevention of high salt diet-induced cardiac hypertrophy and fibrosis by spironolactone. | American journal of hypertension 20030401 |
New antihypertensive drug class. | The American journal of nursing 20030401 |
[Respiratory infections in adults hospitalized in internal medicine and pneumology departments. DIRA (Adult Respiratory Infection Day) study]. | Enfermedades infecciosas y microbiologia clinica 20030401 |
ACOG releases guidelines on diagnosis and management of polycystic ovary syndrome. | American family physician 20030401 |
Ebstein's anomaly in a beagle dog. | The Journal of veterinary medical science 20030401 |
[Effects of antihypertensive drugs on erectile function and number of nNOS-containing nerve fibers in spontaneously hypertensive rats]. | Zhonghua nan ke xue = National journal of andrology 20030401 |
Use of cyproterone acetate, finasteride, and spironolactone to treat idiopathic hirsutism. | Fertility and sterility 20030401 |
Aldosterone antagonism in addition to angiotensin-converting enzyme inhibitors in heart failure. | Minerva cardioangiologica 20030401 |
Ongoing trials of cardiac resynchronisation. | Minerva cardioangiologica 20030401 |
[Pharmacotherapy of chronic heart failure]. | Zeitschrift fur arztliche Fortbildung und Qualitatssicherung 20030401 |
Comparison of the efficiency of anti-androgenic regimens consisting of spironolactone, Diane 35, and cyproterone acetate in hirsutism. | Acta medica Okayama 20030401 |
Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: effects of 11 beta-hydroxysteroid dehydrogenase inactivation. | Endocrinology 20030301 |
Aldo is back: recent advances and unresolved controversies in hyperaldosteronism. | Current opinion in nephrology and hypertension 20030301 |
Eplerenone. | Nature reviews. Drug discovery 20030301 |
Na/H exchange isoform 1 is involved in mineralocorticoid/salt-induced cardiac injury. | Hypertension (Dallas, Tex. : 1979) 20030301 |
Nongenomic effects of aldosterone on human renal cells. | The Journal of clinical endocrinology and metabolism 20030301 |
The EuroHeart Failure Survey programme--a survey on the quality of care among patients with heart failure in Europe. Part 2: treatment. | European heart journal 20030301 |
Single- and repeated-dose pharmacokinetics of eplerenone, a selective aldosterone receptor blocker, in rats. | Xenobiotica; the fate of foreign compounds in biological systems 20030301 |
Possible captopril-induced toxic epidermal necrolysis. | The Annals of pharmacotherapy 20030301 |
An unusual cause of hypokalemic paralysis: chronic licorice ingestion. | The American journal of the medical sciences 20030301 |
Bedside B-type natriuretic peptide and functional capacity in chronic heart failure. | European journal of heart failure 20030301 |
Effects of a beta-blocker and spironolactone on plasma homocysteine levels. | International journal of cardiology 20030301 |
Biotransformations of the cardiovascular drugs mexrenone and canrenone. | Journal of natural products 20030301 |
Digoxin remains useful in the management of chronic heart failure. | The Medical clinics of North America 20030301 |
Aldosterone as a target in congestive heart failure. | The Medical clinics of North America 20030301 |
Revisiting salt and water retention: new diuretics, aquaretics, and natriuretics. | The Medical clinics of North America 20030301 |
Metabolic modulation and optimization of energy consumption in heart failure. | The Medical clinics of North America 20030301 |
Eplerenone. Pharmacia. | Current opinion in investigational drugs (London, England : 2000) 20030301 |
Interdomain interactions in the mineralocorticoid receptor. | Molecular and cellular endocrinology 20030227 |
[Conn syndrome as cause of stubborn hypertension. Which hypertensives should you screen?]. | MMW Fortschritte der Medizin 20030227 |
Ruthenium-catalyzed carbonylative cycloaddition of alpha-keto lactones with alkenes or alkynes: the participation of an ester-carbonyl group in cycloaddition reactions as the two-atom assembling unit. | The Journal of organic chemistry 20030221 |
Effect of spironolactone on cardiac sympathetic nerve activity and left ventricular remodeling in patients with dilated cardiomyopathy. | Journal of the American College of Cardiology 20030219 |
Spironolactone and its main metabolite, canrenoic acid, block human ether-a-go-go-related gene channels. | Circulation 20030218 |
A validated SPE-LC-MS/MS assay for Eplerenone and its hydrolyzed metabolite in human urine. | Journal of pharmaceutical and biomedical analysis 20030205 |
Central mineralocorticoid receptor blockade decreases plasma TNF-alpha after coronary artery ligation in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20030201 |
Aldosterone: a risk factor for vascular disease. | Current hypertension reports 20030201 |
Nadolol plus spironolactone in the prophylaxis of first variceal bleed in nonascitic cirrhotic patients: A preliminary study. | Hepatology (Baltimore, Md.) 20030201 |
Route of steroid-activated macromolecules through nuclear pores imaged with atomic force microscopy. | Biochemical Society transactions 20030201 |
Lack of clinically significant interference by spironolactone with the AxSym Digoxin II assay. | Therapeutic drug monitoring 20030201 |
Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells. | Gastroenterology 20030201 |
False claims of blood pressure-independent protection by blockade of the renin angiotensin aldosterone system? | Hypertension (Dallas, Tex. : 1979) 20030201 |
Renoprotection by ACE inhibition or aldosterone blockade is blood pressure-dependent. | Hypertension (Dallas, Tex. : 1979) 20030201 |
Digoxin increases mortality among women with congestive heart failure. | The Journal of family practice 20030201 |
Spironolactone responsive familial hypertension. A potentially high prevalence of mineralocorticoid disease in Oman. | Saudi medical journal 20030201 |
Becker's nevus with ipsilateral breast hypoplasia: improvement with spironolactone. | The Journal of dermatology 20030201 |
Barriers to accurate diagnosis and effective management of heart failure in primary care: qualitative study. | BMJ (Clinical research ed.) 20030125 |
[Treatment refractory hypertension with atrophic kidney: attending to one and not neglecting the other]. | Praxis 20030122 |
[Aldosterone and its antagonists in heart failure]. | Presse medicale (Paris, France : 1983) 20030118 |
Complications of inappropriate use of spironolactone in heart failure: when an old medicine spirals out of new guidelines. | Journal of the American College of Cardiology 20030115 |
Spironolactone in chronic heart failure:all's well that ends well. | Journal of the American College of Cardiology 20030115 |
Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-RasA and MAPK1/2 signaling. | American journal of physiology. Heart and circulatory physiology 20030101 |
Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity. | Kidney international 20030101 |
Combined effects of enalapril and spironolactone in hamsters with dilated cardiomyopathy. | Journal of cardiovascular pharmacology 20030101 |
Mineralocorticoid receptor function in major depression. | Archives of general psychiatry 20030101 |
Effectiveness of aldosterone blockade in patients with diabetic nephropathy. | Hypertension (Dallas, Tex. : 1979) 20030101 |
Aldosterone-induced cardiac damage: focus on blood pressure independent effects. | American journal of hypertension 20030101 |
Norlanostane and lanostane glycosides from the bulbs of Chionodoxa luciliae and their cytotoxic activity. | Chemical & pharmaceutical bulletin 20030101 |
American College of Cardiology/American Heart Association Chronic Heart Failure Evaluation and Management guidelines: relevance to the geriatric practice. | Journal of the American Geriatrics Society 20030101 |
Complement-inhibiting iridoids from Morinda morindoides. | Journal of natural products 20030101 |
Implementing guidelines in primary care: can population impact measures help? | BMC public health 20030101 |
Resistance artery mechanics and composition in angiotensin II-infused rats: effects of aldosterone antagonism. | Journal of hypertension 20030101 |
The role of angiotensin II receptor blockers in the treatment of heart failure patients. | Congestive heart failure (Greenwich, Conn.) 20030101 |
Update and future of systemic acne treatment. | Dermatology (Basel, Switzerland) 20030101 |
Update and future of hormonal therapy in acne. | Dermatology (Basel, Switzerland) 20030101 |
The effects of spironolactone monotherapy on blood pressure and myocardial remodeling in spontaneously hypertensive rats: a stereological study. | Journal of biomedical science 20030101 |
Albumin effects on drug absorption and metabolism in reconstructed epidermis and excised pig skin. | ALTEX 20030101 |
Humane endpoints in the efficacy testing of swine erysipelas vaccines. | ALTEX 20030101 |
[Totally artificial training model for coronary heart surgery: the renunciation of animal experiments?]. | ALTEX 20030101 |
Extraction of a monospecific Coombs-reagent from chicken eggs. | ALTEX 20030101 |
[Animal experimentation statistics in Germany: 2 million mark exceeded]. | ALTEX 20030101 |
[The 'sewage unit fish' must further die]. | ALTEX 20030101 |
Polycystic ovarian syndrome. A challenge for occupational health nursing. | AAOHN journal : official journal of the American Association of Occupational Health Nurses 20030101 |
[Hormonal treatments of acne]. | Annales de dermatologie et de venereologie 20030101 |
[Investigation of hyperaldosteronism in the hypertensive patient. Why? When? How?]. | Archives des maladies du coeur et des vaisseaux 20030101 |
Aldosterone receptor antagonists: focus on eplerenone. | Progress in cardiovascular nursing 20030101 |
The role of hormones and hormonal treatments in premenstrual syndrome. | CNS drugs 20030101 |
[4th World Congress on Alternatives--impressions]. | ALTEX 20030101 |
[INVITOX 2002: 12th International workshop on in vitro toxicology]. | ALTEX 20030101 |
[Workshop-report: classes of 'protection of animals' concept in schools]. | ALTEX 20030101 |
[Self experimentation and in vitro research will not suffice: a plea for more refinement]. | ALTEX 20030101 |
[Additional comments on the introduction of fish toxicity tests]. | ALTEX 20030101 |
[Boycott of leather goods]. | ALTEX 20030101 |
Eplerenone, a new selective aldosterone blocker. | Current pharmaceutical design 20030101 |
Effect of the addition of a beta-blocker on left ventricular remodeling and prognosis in patients with dilated cardiomyopathy treated with angiotensin-converting enzyme inhibitor. | Journal of cardiovascular pharmacology 20030101 |
Transcardiac gradient of aldosterone before and after spironolactone in patients with congestive heart failure. | Journal of cardiovascular pharmacology 20030101 |
Cutaneous drug reaction case reports: from the world literature. | American journal of clinical dermatology 20030101 |
Aldosterone receptor blockade: a therapy resurrected. | Heart disease (Hagerstown, Md.) 20030101 |
Aldosterone and aldosterone antagonism in cardiovascular disease: focus on eplerenone (Inspra). | Heart disease (Hagerstown, Md.) 20030101 |
Protein-losing enteropathy in patients with Fontan circulation: is it triggered by infection? | Critical care (London, England) 20030101 |
[Bartter syndrome and it's neonatal type]. | Medicina (Kaunas, Lithuania) 20030101 |
Comparison of the reactivity of human and rabbit blood towards pyrogenic stimuli. | ALTEX 20030101 |
Suitability of temperature-sensitive transponders to measure body temperature during animal experiments required for regulatory tests. | ALTEX 20030101 |
Development of an in vitro model to study oxidative DNA damage in human coronary artery endothelial cells. | ALTEX 20030101 |
Proof of principle: detection of genotoxicity by a fluorescence-based recombination test in mammalian cells. | ALTEX 20030101 |
Internet laboratory for predicting harmful effects triggered by drugs and chemicals--a progress report. | ALTEX 20030101 |
[Third statistical report on the numbers of laboratory animals used in the European Union--tendencies, problems, decisions]. | ALTEX 20030101 |
[Self experimentation and in vitro research will not suffice: a plea for treatment]. | ALTEX 20030101 |
[German research statistics in biomedical investigations]. | ALTEX 20030101 |
[EU: third report of the EU research animal numbers presented]. | ALTEX 20030101 |
[German Research Society forms a graduate collage of bioethics in Tubingen]. | ALTEX 20030101 |
[Predictive toxicology: in silico modelling and expert systems]. | ALTEX 20030101 |
[Animal welfare in flux--scandals, animal welfare and solutions]. | ALTEX 20030101 |
[Science in the service of animal welfare-UFAW symposium 2003]. | ALTEX 20030101 |
[Towards better in vitro methods: the replacement of fetal bovine serum]. | ALTEX 20030101 |
Epidemiology, pathophysiology, prognosis, and treatment of systolic and diastolic heart failure in elderly patients. | Heart disease (Hagerstown, Md.) 20030101 |
Treatment of chronic heart failure in long-term care facilities: implications of recent heart failure guidelines recommendations. | Archives of gerontology and geriatrics 20030101 |
Drug therapy of heart failure in the elderly. | The American journal of geriatric cardiology 20030101 |
Does the treatment of primary hyperaldosteronism influence glucose tolerance? | Physiological research 20030101 |
Cost-effectiveness of spironolactone in patients with severe heart failure. | Irish journal of medical science 20030101 |
Eplerenone: a selective aldosterone blocker. | Cardiovascular drug reviews 20030101 |
Hyperkalemia, congestive heart failure, and aldosterone receptor antagonism. | Congestive heart failure (Greenwich, Conn.) 20030101 |
Effects of glycyrrhizin on renal functions in association with the regulation of water channels. | The American journal of Chinese medicine 20030101 |
[Anti-angiogenic effects of aldosterone antagonists in the fibrin chamber in rats]. | Archives des maladies du coeur et des vaisseaux 20030101 |
Latent hepatitis B virus (HBV) infection and HBV DNA integration is associated with further transformation of hepatoma cells in vitro. | ALTEX 20030101 |
V79 Chinese hamster cells genetically engineered for polymorphic cytochrome P450 2D6 and their predictive value for humans. | ALTEX 20030101 |
The new EU Chemicals Policy--comments of Eurogroup for Animal Welfare and the Deutscher Tierschutzbund on the EU-Commission's REACH system Consultation Documents. | ALTEX 20030101 |
Aldosterone receptor antagonists for hypertension: what do they offer? | Drugs 20030101 |
[Efficacy of an aldosterone receptor blocker eplerenone in high risk survivors of acute myocardial infarction with signs of heart failure: results of EPHESUS]. | Kardiologiia 20030101 |
Arterial expression of 5-HT2B and 5-HT1B receptors during development of DOCA-salt hypertension. | BMC pharmacology 20030101 |
Eplerenone: a selective aldosterone receptor antagonist for hypertension and heart failure. | Heart disease (Hagerstown, Md.) 20030101 |
[6. Mini symposium Xenotransplantation. D-Berlin, Robert-Koch-Institute, May 9, 2003]. | ALTEX 20030101 |
[TVT seminar about animal experimentation committees. D-Darmstadt, June 13, 2003]. | ALTEX 20030101 |
Methods of substitution in laparoscopic surgical training. | ALTEX 20030101 |
[Animal experimentation in Switzerland 2002: in college it was done 'like wild'!]. | ALTEX 20030101 |
Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne. | The Cochrane database of systematic reviews 20030101 |
Cyproterone acetate for hirsutism. | The Cochrane database of systematic reviews 20030101 |
The renin-angiotensin-aldosterone system in patients with depression compared to controls--a sleep endocrine study. | BMC psychiatry 20030101 |
Diagnosis and management of heart failure in the long-term care setting. | Director (Cincinnati, Ohio) 20030101 |
Alternatives to animal testing: research, trends, validation, regulatory acceptance. | ALTEX 20030101 |
The 3Rs and animal welfare - conflict or the way forward? | ALTEX 20030101 |
[Man and his fellow-creatures under ethical aspects]. | ALTEX 20030101 |
[Xenotransplantation from a Christian-ethical perspective]. | ALTEX 20030101 |
[Question the animal experiment in a new way]. | ALTEX 20030101 |
Alternatives to the use of fetal bovine serum: serum-free cell culture. | ALTEX 20030101 |
New therapy update. Inspra (eplerenone tablets). | Congestive heart failure (Greenwich, Conn.) 20030101 |
Immunosuppressive therapy for heart failure: a guide to patient selection. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101 |
[Prevalence of type 2 diabetes mellitus in an internal medicine ambulatory care department]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101 |
[Abnormal positions of the heart. An analysis on 1039 cases]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101 |
[Atrio-ventricular canal: possibilities of recovery]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101 |
The European Society of Cardiology working group on heart failure: Heart Failure Update 2003. | Heart failure monitor 20030101 |
CHART: congestive cardiac failure in hospitals, an Australian review of treatment. | Heart, lung & circulation 20030101 |
Preventing sudden death and the use of prophylactic implanted defibrillators. | Indian pacing and electrophysiology journal 20030101 |
Heart rate variability analysis in general medicine. | Indian pacing and electrophysiology journal 20030101 |
Excerpts from electrophysiology sessions at the European Society of Cardiology Congress 2002-Berlin. | Indian pacing and electrophysiology journal 20030101 |
Impact of smoking reduction on coronary heart disease mortality trends during 1981-2000 in England and Wales. | Tobacco induced diseases 20030101 |
Receptor-dependent regulation of the CYP3A4 gene. | Toxicology 20021227 |
Rapid non-genomic inhibition of ATP-induced Cl- secretion by dexamethasone in human bronchial epithelium. | The Journal of physiology 20021215 |
Effects of long-term monotherapy with eplerenone, a novel aldosterone blocker, on progression of left ventricular dysfunction and remodeling in dogs with heart failure. | Circulation 20021203 |
Aldosterone. | Advances in physiology education 20021201 |
Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5. | Drug metabolism and disposition: the biological fate of chemicals 20021201 |
Selective aldosterone blockade prevents angiotensin II/salt-induced vascular inflammation in the rat heart. | Endocrinology 20021201 |
Hyperaldosteronism among black and white subjects with resistant hypertension. | Hypertension (Dallas, Tex. : 1979) 20021201 |
Screening for 18 diuretics and probenecid in doping analysis by liquid chromatography-tandem mass spectrometry. | Biomedical chromatography : BMC 20021201 |
Comparison of spironolactone and spironolactone plus finasteride in the treatment of hirsutism. | Fertility and sterility 20021201 |
Regulatory effects of salt diet on renal renin-angiotensin-aldosterone, and kallikrein-kinin systems. | International immunopharmacology 20021201 |
Molecular mechanisms of myocardial remodeling. The role of aldosterone. | Journal of molecular and cellular cardiology 20021201 |
Appraisal of the role of angiotensin II and aldosterone in ventricular myocyte apoptosis in adult normotensive rat. | Journal of molecular and cellular cardiology 20021201 |
Cardiomyocyte volume-weighted nuclear volume and spironolactone therapy in spontaneously hypertensive rats. | Analytical and quantitative cytology and histology 20021201 |
Do diuretics and aldosterone receptor antagonists improve ventricular remodeling? | Journal of cardiac failure 20021201 |
Sudden cardiac death in dilated cardiomyopathy -- therapeutic options. | Herz 20021201 |
Heart failure. | Clinical evidence 20021201 |
[Primary aldosteronism and pregnancy: report of 2 cases]. | Revista medica de Chile 20021201 |
Evaluation of a unique oral contraceptive (Yasmin) in the management of premenstrual dysphoric disorder. | The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20021201 |
Increased carotid wall elastic modulus and fibronectin in aldosterone-salt-treated rats: effects of eplerenone. | Circulation 20021126 |
Beneficial neurohormonal profile of spironolactone in severe congestive heart failure: results from the RALES neurohormonal substudy. | Journal of the American College of Cardiology 20021106 |
Sodium transporter abundance profiling in kidney: effect of spironolactone. | American journal of physiology. Renal physiology 20021101 |
Increasing plasma potassium with amiloride shortens the QT interval and reduces ventricular extrasystoles but does not change endothelial function or heart rate variability in chronic heart failure. | Heart (British Cardiac Society) 20021101 |
Aldosterone induces a vascular inflammatory phenotype in the rat heart. | American journal of physiology. Heart and circulatory physiology 20021101 |
Aldactone therapy in a peritoneal dialysis patient with decreased left ventricular function. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021101 |
Mineralocorticoid receptor function in patients with posttraumatic stress disorder. | The American journal of psychiatry 20021101 |
Aldosterone-induced inflammation in the rat heart : role of oxidative stress. | The American journal of pathology 20021101 |
The effect of post-transplant spironolactone on daily potassium requirements in patients undergoing autologous stem cell transplantation. | Bone marrow transplantation 20021101 |
New biology of aldosterone, and experimental studies on the selective aldosterone blocker eplerenone. | American heart journal 20021101 |
Clinical implications of aldosterone blockade. | American heart journal 20021101 |
Rapid stimulation of cyclic AMP production by aldosterone in rat inner medullary collecting ducts. | The Journal of endocrinology 20021101 |
Clinical treatment regimens for chronic heart failure: a review. | Expert opinion on pharmacotherapy 20021101 |
Relative long-term effects of spironolactone in conjunction with an angiotensin-converting enzyme inhibitor on left ventricular mass and diastolic function in patients with essential hypertension. | Hypertension research : official journal of the Japanese Society of Hypertension 20021101 |
Premenstrual syndrome. Evidence-based treatment in family practice. | Canadian family physician Medecin de famille canadien 20021101 |
Oral contraception: trends over time. | The Journal of reproductive medicine 20021101 |
Safety and efficacy of a new oral contraceptive containing drospirenone. | The Journal of reproductive medicine 20021101 |
[Adaptation of guidelines for the treatment of chronic heart failure in a specialized heart failure clinic]. | Wiener klinische Wochenschrift 20021031 |
[Female sexual dysfunction as adverse effect of pharmacological treatment]. | Ugeskrift for laeger 20021007 |
Aldosterone inhibits HCO absorption via a nongenomic pathway in medullary thick ascending limb. | American journal of physiology. Renal physiology 20021001 |
Eplerenone--a novel selective aldosterone blocker. | The Annals of pharmacotherapy 20021001 |
Combined effects of metoprolol and spironolactone in dilated cardiomyopathic hamsters. | Journal of cardiovascular pharmacology 20021001 |
Influence of antihypertensive medication on aldosterone and renin concentration in the differential diagnosis of essential hypertension and primary aldosteronism. | Clinical endocrinology 20021001 |
Spironolactone improves angiotensin-induced vascular changes and oxidative stress. | Hypertension (Dallas, Tex. : 1979) 20021001 |
Spironolactone improves cardiac sympathetic nerve activity and symptoms in patients with congestive heart failure. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20021001 |
The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. | Endocrine reviews 20021001 |
Hyperaldosteronism: the internist's hypertensive disease. | The American journal of the medical sciences 20021001 |
Monitoring of transtubular potassium gradient in the diuretic management of patients with cirrhosis and ascites. | Liver 20021001 |
[Significance of combining spironolactone during long-term administration of ARB]. | Nihon rinsho. Japanese journal of clinical medicine 20021001 |
The role of aldosterone receptor blockade in the management of cardiovascular disease. | Current opinion in investigational drugs (London, England : 2000) 20021001 |
[Medical treatment of chronic congestive heart failure]. | La Revue du praticien 20021001 |
Implantation techniques and chronic lead parameters of biventricular pacing dual-chamber defibrillators. | Journal of cardiovascular electrophysiology 20021001 |
On the inhibitory action of 29 drugs having side effect gynecomastia on estrogen production. | The Journal of steroid biochemistry and molecular biology 20021001 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20021001 |
[Selective aldosterone blocker for hypertension and heart failure. Better tolerance than previous drugs]. | MMW Fortschritte der Medizin 20020926 |
Efficient synthesis of a 4,5-epoxy-2-cyclohexen-1-one derivative bearing a spirolactone via a Diels-Alder reaction with high pi-facial selectivity: a synthetic study towards scyphostatin. | Chemical communications (Cambridge, England) 20020921 |
Estimation of glomerular filtration rate to prevent life-threatening hyperkalemia due to combined therapy with spironolactone and angiotensin-converting enzyme inhibition or angiotensin receptor blockade. | The American journal of cardiology 20020915 |
Hyperkalemia in congestive heart failure patients aged 63 to 85 years with subclinical renal disease. | The American journal of cardiology 20020915 |
Aldosterone impairs insulin responsiveness in U-937 human promonocytic cells via the downregulation of its own receptor. | Cell biochemistry and function 20020901 |
Mineralocorticoid regulation of cyclooxygenase-2 expression in rat renal medulla. | American journal of physiology. Renal physiology 20020901 |
Central effects of mineralocorticoids on blood pressure: new answers, new questions. | Journal of hypertension 20020901 |
Influence of sodium intake on the cardiovascular and renal effects of brain mineralocorticoid receptor blockade in normotensive rats. | Journal of hypertension 20020901 |
Inhibition of 3 alpha/beta,20 beta-hydroxysteroid dehydrogenase by dexamethasone, glycyrrhetinic acid and spironolactone is attenuated by deletion of 12 carboxyl-terminal residues. | Biological & pharmaceutical bulletin 20020901 |
Multicenter hospital study on prescribing patterns for prophylaxis and treatment of complications of cirrhosis. | European journal of clinical pharmacology 20020901 |
Prevention of heart failure. | Current opinion in cardiology 20020901 |
Mucinous digestive tumors. Case reports and review of the literature. | Romanian journal of gastroenterology 20020901 |
The pathophysiology of aldosterone in the cardiovascular system. | Annals of the New York Academy of Sciences 20020901 |
Quality and outcomes of heart failure care in older adults: role of multidisciplinary disease-management programs. | Journal of the American Geriatrics Society 20020901 |
Cutaneous reaction to oral spironolactone with positive patch test. | Contact dermatitis 20020901 |
Spironolactone increases integrin beta3 gene expression in kidney and heart muscle cells. | Molecular and cellular endocrinology 20020830 |
Traumatic brain injury regulates adrenocorticosteroid receptor mRNA levels in rat hippocampus. | Brain research 20020823 |
[Let's read the domestic literature. ACE-inhibitors and spironolactone-induced hyperkalemia]. | Orvosi hetilap 20020804 |
Efficacy of eplerenone added to renin-angiotensin blockade in hypertensive patients. | Hypertension (Dallas, Tex. : 1979) 20020801 |
Mineralocorticoid and angiotensin receptor antagonism during hyperaldosteronemia. | Hypertension (Dallas, Tex. : 1979) 20020801 |
Rapid effects of aldosterone and spironolactone in the isolated working rat heart. | Hypertension (Dallas, Tex. : 1979) 20020801 |
Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertension. | American journal of hypertension 20020801 |
Mineralocorticoid receptors and pathophysiological roles for aldosterone in the cardiovascular system. | Journal of hypertension 20020801 |
Liddle syndrome in a newborn infant. | Pediatric nephrology (Berlin, Germany) 20020801 |
Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension. | Clinical science (London, England : 1979) 20020801 |
[Intervention strategies in refractory heart failure]. | Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20020801 |
[The significance of aldosterone in chronic heart failure: the RALES study]. | Vnitrni lekarstvi 20020801 |
From HAIR-AN to eternity. | Journal of pediatric and adolescent gynecology 20020801 |
Designing complex group sequential survival trials. | Statistics in medicine 20020730 |
Long-term, dose-dependent effects of spironolactone on left ventricular function and exercise tolerance in patients with chronic heart failure. | Journal of the American College of Cardiology 20020717 |
Results from late-breaking clinical trial sessions at the American College of Cardiology 51st Annual Scientific Session. | Journal of the American College of Cardiology 20020703 |
The renin-angiotensin-aldosterone system excites hypothalamic paraventricular nucleus neurons in heart failure. | American journal of physiology. Heart and circulatory physiology 20020701 |
Muscle strength, Na,K-pumps, magnesium and potassium in patients with alcoholic liver cirrhosis -- relation to spironolactone. | Journal of internal medicine 20020701 |
Hormonal therapies in acne. | Expert opinion on pharmacotherapy 20020701 |
Present and future pharmacotherapy for heart failure. | Expert opinion on pharmacotherapy 20020701 |
Life-threatening hyperkalemia: a complication of spironolactone for heart failure in a patient with renal insufficiency. | Anesthesia and analgesia 20020701 |
Postoperative synthetic human atrial natriuretic peptide infusion and oral spironolactone administration for a patient with giant atria and low plasma level of atrial natriuretic peptide. | The Journal of thoracic and cardiovascular surgery 20020701 |
Aldosterone breakthrough during angiotensin II receptor antagonist therapy in stroke-prone spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20020701 |
Endogenous and exogenous digoxin-like immunoreactive substances: impact on therapeutic drug monitoring of digoxin. | American journal of clinical pathology 20020701 |
Pharmacoepidemiologic detection of calcium channel blocker-induced change on digoxin clearance using multiple trough screen analysis. | Biopharmaceutics & drug disposition 20020701 |
Investigation of structure-activity relationship on 17-spirolactone derivatives: the electronic-topological approach. | Farmaco (Societa chimica italiana : 1989) 20020701 |
Aldosterone antagonists in congestive heart failure. | Current opinion in investigational drugs (London, England : 2000) 20020701 |
The pharmacological treatment of heart failure: are we looking at the sunset of the neurohormonal hypothesis. | Italian heart journal : official journal of the Italian Federation of Cardiology 20020701 |
Oral contraceptives as anti-androgenic treatment of acne. | Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 20020701 |
Enantiospecific synthesis of the phospholipase A2 inhibitor (-)-cinatrin B. | The Journal of organic chemistry 20020628 |
Regulation of rat multidrug resistance protein 2 by classes of prototypical microsomal enzyme inducers that activate distinct transcription pathways. | Toxicological sciences : an official journal of the Society of Toxicology 20020601 |
Aldosterone augments adrenomedullin production without stimulating pro-adrenomedullin N-terminal 20 peptide secretion in vascular smooth muscle cells. | Journal of hypertension 20020601 |
[Aldosterone blockade in heart failure. So much for so little]. | Medicina clinica 20020601 |
New HER2-directed therapies for breast cancer. Commentary re: C. I. Spiridon et al., Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity. Clin. Cancer Res., 8: 1720-1730, 2002. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020601 |
Functional activities of the colon of the desert gerbil (Gerbillus cheesmani). | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020601 |
Sildenafil in primary pulmonary hypertension--is there a subset of patients who respond favourably? | The Canadian journal of cardiology 20020601 |
Interconversion pharmacokinetics of eplerenone, a selective aldosterone blocker, and its lactone-ring open form. | Journal of pharmaceutical sciences 20020601 |
[Aldosterone--classic and non classic effects]. | Harefuah 20020601 |
Aldosterone stimulates angiotensin-converting enzyme expression and activity in rat neonatal cardiac myocytes. | Journal of cardiac failure 20020601 |
Heart failure. | Clinical evidence 20020601 |
Premenstrual syndrome. | Clinical evidence 20020601 |
Treatment of depression associated with the menstrual cycle: premenstrual dysphoria, postpartum depression, and the perimenopause. | Dialogues in clinical neuroscience 20020601 |
Furosemide and spironolactone reduce transmigration of leukocytes through endothelial cell monolayers. | Journal of toxicology and environmental health. Part A 20020510 |
Mineralocorticoid receptor antagonism in experimental atherosclerosis. | Circulation 20020507 |
Nongenomic effects of aldosterone: cellular aspects and clinical implications. | Steroids 20020501 |
Dyotropic rearrangement facilitated proximal functionalization and oxidative removal of angular methyl groups: efficient syntheses of 23'-deoxy cephalostatin 1 analogues. | Journal of the American Chemical Society 20020501 |
Syndrome of inappropriate antidiuretic hormone-induced hyponatremia associated with amiodarone. | Pharmacotherapy 20020501 |
[Increased thrombocyte activation in dilated cardiomyopathy: a risk factor for development of ventricular thrombosis despite anticoagulant therapy?]. | Zeitschrift fur Kardiologie 20020501 |
New treatments for myocardial fibrosis. | Cardiovascular drugs and therapy 20020501 |
[Acne and hormones]. | La Revue du praticien 20020415 |
Aldosterone synthase (CYP11B2) expression and myocardial fibrosis in the failing human heart. | Clinical science (London, England : 1979) 20020401 |
Expanding the outcomes in clinical trials of heart failure: the quality of life and economic components of EPHESUS (EPlerenone's neuroHormonal Efficacy and SUrvival Study). | American heart journal 20020401 |
Aldosterone receptor blockade in the management of heart failure. | Heart failure reviews 20020401 |
The role of spironolactone in the treatment of patients with refractory hypertension. | American journal of hypertension 20020401 |
Premenstrual syndrome. | Minerva ginecologica 20020401 |
[Simultaneous analysis of four diuretic drugs by HPLC and its application to health food supplements advertising weight reduction]. | Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20020401 |
Common treatment of polycystic ovarian syndrome and major depressive disorder: case report and review. | Current drug targets. Immune, endocrine and metabolic disorders 20020401 |
Inhibitory effects of cortical steroids and adrenocorticotropic hormone on catecholamine secretion in guinea-pig perfused adrenal glands. | Autonomic & autacoid pharmacology 20020401 |
Left ventricular assist device. | The New England journal of medicine 20020328 |
Sudden death due to cardiac arrhythmias. | The New England journal of medicine 20020321 |
Chronic heart failure guidelines. | European heart journal 20020301 |
Malakoplakia of liver diagnosed by a needle core biopsy: a case report and review of the literature. | Archives of pathology & laboratory medicine 20020301 |
Digoxin assays: frequent, substantial, and potentially dangerous interference by spironolactone, canrenone, and other steroids. | Clinical chemistry 20020301 |
Anti-androgens for the treatment of hirsutism. | Expert opinion on investigational drugs 20020301 |
Male LH-independent sexual precocity in a 3.5-year-old boy caused by a somatic activating mutation of the LH receptor in a Leydig cell tumor. | The Journal of clinical endocrinology and metabolism 20020301 |
Is aldosterone the missing link in refractory hypertension?: aldosterone-to-renin ratio as a marker of inappropriate aldosterone activity. | Journal of human hypertension 20020301 |
Primary aldosteronism, a common entity? the myth persists. | Journal of human hypertension 20020301 |
My hair is thinning on the top of my head. What treatments are available for hair loss in women? | Health news (Waltham, Mass.) 20020301 |
Atypical dose-route-dependent food effects of eplerenone in the dog: presence of food effects following intravenous dosing and lack of food effects of following oral dosing. | Journal of pharmaceutical sciences 20020301 |
Influence of progressive renal dysfunction in chronic heart failure. | European journal of heart failure 20020301 |
Diuretics in the treatment of patients who present congestive heart failure and hypertension. | Journal of human hypertension 20020301 |
[Secondary forms of hypertension. 5. Hypertension caused by Cushing syndrome and Conn's disease]. | MMW Fortschritte der Medizin 20020227 |
Spironolactone and ACE inhibition in chronic renal failure. | The New England journal of medicine 20020207 |
Spironolactone and ACE inhibition in chronic renal failure. | The New England journal of medicine 20020207 |
Effects of brain mineralocorticoid receptor blockade on blood pressure and renal functions in DOCA-salt hypertension. | European journal of pharmacology 20020202 |
Hypovolemia and neurovascular control during orthostatic stress. | American journal of physiology. Heart and circulatory physiology 20020201 |
Spironolactone abolishes the relationship between aldosterone and plasminogen activator inhibitor-1 in humans. | The Journal of clinical endocrinology and metabolism 20020201 |
Impaired endothelium-mediated vasodilation in heart failure: clinical evidence and the potential for therapy. | Journal of cardiac failure 20020201 |
Update on treatment for congestive heart failure. | Medicine and health, Rhode Island 20020201 |
Cardiac damage prevention by eplerenone: comparison with low sodium diet or potassium loading. | Hypertension (Dallas, Tex. : 1979) 20020201 |
Spironolactone blocks glucocorticoid-mediated hearing preservation in autoimmune mice. | The Laryngoscope 20020201 |
[The process of drug development. The 'case' of spironolactone]. | Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20020201 |
Highlights of the 22nd French pharmacovigilance meeting. | Prescrire international 20020201 |
Addition of spironolactone to angiotensin-converting enzyme inhibition in heart failure improves endothelial vasomotor dysfunction: role of vascular superoxide anion formation and endothelial nitric oxide synthase expression. | Journal of the American College of Cardiology 20020116 |
[Future molecules in heart failure]. | Presse medicale (Paris, France : 1983) 20020112 |
Unusual lactones from Cananga odorata (Annonaceae). | Journal of agricultural and food chemistry 20020102 |
Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats. | The Journal of pharmacology and experimental therapeutics 20020101 |
Induction profile of rat organic anion transporting polypeptide 2 (oatp2) by prototypical drug-metabolizing enzyme inducers that activate gene expression through ligand-activated transcription factor pathways. | The Journal of pharmacology and experimental therapeutics 20020101 |
Progestogens in hormonal replacement therapy: new molecules, risks, and benefits. | Menopause (New York, N.Y.) 20020101 |
Mifepristone protects CA1 hippocampal neurons following traumatic brain injury in rat. | Neuroscience 20020101 |
Normokalemic hyperaldosteronism in patients with resistant hypertension. | The Israel Medical Association journal : IMAJ 20020101 |
Primary aldosteronism: the most frequent form of secondary hypertension? | The Israel Medical Association journal : IMAJ 20020101 |
Impact of aldosterone on vascular pathophysiology. | Congestive heart failure (Greenwich, Conn.) 20020101 |
Serum leptin levels in patients with primary hyperaldosteronism before and after treatment: relationships to insulin sensitivity. | Journal of human hypertension 20020101 |
Current limitations in treatment of heart failure: new avenues and treatment options. | Journal of cardiovascular electrophysiology 20020101 |
Spironolactone: is it a novel drug for the prevention of amphotericin B-related hypokalemia in cancer patients? | European journal of clinical pharmacology 20020101 |
Diuretics acting on the distal renal tubule for preterm infants with (or developing) chronic lung disease. | The Cochrane database of systematic reviews 20020101 |
Neonatal Bartter syndrome. | Indian journal of pediatrics 20020101 |
Aldosterone as a mediator in cardiovascular injury. | Cardiology in review 20020101 |
[Clinical study of the month. Effects of valsartan in chronic heart failure: the VAL-HeFT study]. | Revue medicale de Liege 20020101 |
Current guidelines in heart failure management. | Ethnicity & disease 20020101 |
Standardised in vitro electrophysiologic measurements using isolated perfused porcine hearts--assessment of QT interval alterations. | ALTEX 20020101 |
Multiple-organ harvesting for models of isolated hemoperfused organs of slaughtered pigs. | ALTEX 20020101 |
Novel serum replacement based on bovine ocular fluid: a useful tool for cultivation of different animal cells in vitro. | ALTEX 20020101 |
[Good cell culture practice--implementation of a relational cell culture database]. | ALTEX 20020101 |
Rationale for the use of aldosterone antagonists in congestive heart failure. | Drugs 20020101 |
[Bullous pemphigoid induced by spironolactone]. | Annales de dermatologie et de venereologie 20020101 |
BNP in hormone-guided treatment of heart failure. | Trends in endocrinology and metabolism: TEM 20020101 |
Evidence-based medicine in practice. | ACP journal club 20020101 |
Myocardial changes after spironolactone in spontaneous hypertensive rats. A laser scanning confocal microscopy study. | Journal of cellular and molecular medicine 20020101 |
Interest of the association clonidine-spironolactone in cirrhotic patients with ascites and activation of sympathetic nervous system. | Acta gastro-enterologica Belgica 20020101 |
The blockade of mineralocorticoid hormone signaling provokes dramatic teratogenesis in cultured rat embryos. | International journal of toxicology 20020101 |
Economic evaluation of the randomized aldactone evaluation study (RALES): treatment of patients with severe heart failure. | Cardiovascular drugs and therapy 20020101 |
[Science and ethics]. | ALTEX 20020101 |
[Experimental animal research in the EU legislation]. | ALTEX 20020101 |
[White Paper of the European Commission--strategy for a new chemicals policy]. | ALTEX 20020101 |
The new EU chemicals policy--Discussions on details relevant for animal welfare. | ALTEX 20020101 |
Ecotoxicological assessment of surface waters: a modular approach integrating in vitro methods. | ALTEX 20020101 |
DarT: The embryo test with the Zebrafish Danio rerio--a general model in ecotoxicology and toxicology. | ALTEX 20020101 |
[PCR and ELISA--in vitro alternatives to the mouse-bioassay for assessing the botulinum-neurotoxin-C1 production potential in environmental samples?]. | ALTEX 20020101 |
[Improving the embryonic stem cell test (EST) by establishing molecular endpoints of tissue specific development using murine embryonic stem cells (D3 cells)]. | ALTEX 20020101 |
Immortalisation of ovarian granulosa and Theca cells of the marmoset monkey Calllithrix jacchus. | ALTEX 20020101 |
Comparative study of rabbit pyrogen test and human whole blood assay on human serum albumin. | ALTEX 20020101 |
[Replacement of mouse and rat antibody production test; comparison of sensitivity between the in vitro and in vivo methods]. | ALTEX 20020101 |
HET-CAM bioassay as in vitro alternative to the croton oil test for investigating steroidal and non-steroidal compounds. | ALTEX 20020101 |
The isolated perfused bovine uterus as a model for mucous membrane irritation and inflammation. | ALTEX 20020101 |
Do we need a 'Chair of alternative methods', and where? | ALTEX 20020101 |
A chair on alternatives? | ALTEX 20020101 |
Replacement, reduction and refinement. | ALTEX 20020101 |
Science and society: different bioethical approaches towards animal experimentation. | ALTEX 20020101 |
[Comment on the combined position of the state government, the union of the chemical industry and the industrial mining association, chemistry, energy for the White Paper of the European Commission 'Strategy for future Chemical Policy']. | ALTEX 20020101 |
[On the death of Jurgen Dahl]. | ALTEX 20020101 |
Congestive heart failure due to systolic dysfunction: the Cinderella of cardiovascular management in dialysis patients. | Seminars in dialysis 20020101 |
Bidirectional (positive/negative) interference of spironolactone, canrenone, and potassium canrenoate on serum digoxin measurement: elimination of interference by measuring free digoxin or using a chemiluminescent assay for digoxin. | Journal of clinical laboratory analysis 20020101 |
Spironolactone for the treatment of hypercalciuric hypocalcemia. | Journal of bone and mineral metabolism 20020101 |
[The development and approval of alternative methods to bioassays used for quality assurance, a challenge for the pharmaceutical industry and the authorities]. | ALTEX 20020101 |
Development of an in vitro model to study oxidative DNA damage in human coronary smooth muscle cells. | ALTEX 20020101 |
Animal experimentation in sciences: sadistic nonsense or indispensable necessity? | ALTEX 20020101 |
Use of animals in research: a science--society controversy? The American perspective: animal welfare issues. | ALTEX 20020101 |
Use of animals in research: a science - society controversy? The European perspective. | ALTEX 20020101 |
Acid-base state in patients after cardiac transplantation. | American journal of nephrology 20020101 |
Letter to the editors of the proceedings of a workshop on isolated perfused organs. | ALTEX 20020101 |
Long-term safety of spironolactone in acne: results of an 8-year followup study. | Journal of cutaneous medicine and surgery 20020101 |
Standardised in vitro electrophysiologic measurements using isolated perfused porcine hearts--assessment of QT interval alterations. | ALTEX 20020101 |
Acne: effect of hormones on pathogenesis and management. | American journal of clinical dermatology 20020101 |
[Anti-angiogenesis effects of aldosterone antagonist diuretics]. | Archives des maladies du coeur et des vaisseaux 20020101 |
Hirsuties. | The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia 20020101 |
Hemodynamic effect of spironolactone in liver cirrhosis and propranolol-resistant portal hypertension. | Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20020101 |
Effect of spironolactone on impaired fibrinolysis of hypertensive patients. | Kidney & blood pressure research 20020101 |
Genetic profiling versus drug rotation in the optimisation of antihypertensive treatment. | Clinical medicine (London, England) 20020101 |
[Legal framework and legal-philosophical limitations in research]. | ALTEX 20020101 |
[Christian responsibility and experimental medicine. Experiments with and on humans, experiments on animals]. | ALTEX 20020101 |
[Research and ethical measures]. | ALTEX 20020101 |
[Does scientific-technological progress endanger human dignity?]. | ALTEX 20020101 |
Alternatives to animal experimentation yesterday, today and tomorrow: some thoughts on leaving ECVAM. | ALTEX 20020101 |
Eplerenone: a new aldosterone receptor antagonist--are the FDAs restrictions appropriate? | Journal of clinical hypertension (Greenwich, Conn.) 20020101 |
Balancing diuretic therapy in heart failure: loop diuretics, thiazides, and aldosterone antagonists. | Congestive heart failure (Greenwich, Conn.) 20020101 |
[Contemporary approaches to diagnosis and management of chronic heart failure (summary of the American College of Cardiology/American Heart Association Guidelines)]. | Kardiologiia 20020101 |
[Re: Kay Brune. Altex 19, 3, 2002: Animal experimentation in sciences: sadistic nonsense or indispensible necessity?]. | ALTEX 20020101 |
[Re: Kay Brune. Altex 19, 3, 2002: Animal experimentation in sciences: sadistic nonsense or indispensible necessity?]. | ALTEX 20020101 |
[The ESAC point of view]. | ALTEX 20020101 |
[Sequential esophageal scintigraphy contribution on cardia achalasia diagnosis]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20020101 |
[Synchronous colonic cancers]. | Chirurgia (Bucharest, Romania : 1990) 20020101 |
Racial differences in responses to drug treatment: implications for pharmacotherapy of heart failure. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101 |
Congestive heart failure: what should be the initial therapy and why? | American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101 |
Spironolactone therapy in older patients--the impact of renal dysfunction. | Archives of gerontology and geriatrics 20020101 |
[Recurrent abdominal pain and genital diseases in young girls]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20020101 |
Pathophysiology, diagnosis and treatment of ascites in cirrhosis. | Annals of hepatology 20020101 |
The case of the elusive androgen. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20020101 |
Volume-weighted mean glomerular volume in spontaneously hypertensive rats treated with different doses of spironolactone. | International braz j urol : official journal of the Brazilian Society of Urology 20020101 |
The long QT syndrome. | Indian pacing and electrophysiology journal 20020101 |
[Therapeutic program for ascites. Recommendations from the Swedish Society of Gastroenterology and Gastrointestinal Endoscopy]. | Lakartidningen 20011205 |
Absolute, not relative, changes are important when interpreting trial data. | Journal of the American College of Cardiology 20011201 |
Quantitative distinctions of active site molecular recognition by P-glycoprotein and cytochrome P450 3A4. | Chemical research in toxicology 20011201 |
Abstract, closing summary, and table of contents for Laragh's 25 lessons in pathophysiology and 12 clinical pearls for treating hypertension. | American journal of hypertension 20011201 |
A critical evaluation of the NICE guidelines for post-myocardial infarction prophylaxis. National Institute for Clinical Excellence. | Expert opinion on pharmacotherapy 20011201 |
[Registry of cardiac insufficiency in cardiology]. | Archives des maladies du coeur et des vaisseaux 20011201 |
[Arrhythmia risk stratification in patients with heart failure according to drug treatment and its effects]. | Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20011201 |
Mineralocorticoids and cardiac fibrosis: the decade in review. | Clinical and experimental pharmacology & physiology 20011201 |
Acute exposure to a novel stressor further reduces the habituated corticosterone response to restraint in rats. | Stress (Amsterdam, Netherlands) 20011201 |
Rapid and non-genomic reduction of intracellular [Ca(2+)] induced by aldosterone in human bronchial epithelium. | The Journal of physiology 20011115 |
Role of renin-angiotensin-aldosterone system in salt-sensitive hypertension induced by sensory denervation. | American journal of physiology. Heart and circulatory physiology 20011101 |
Central mineralocorticoid receptor blockade improves volume regulation and reduces sympathetic drive in heart failure. | American journal of physiology. Heart and circulatory physiology 20011101 |
Influence of aldosterone vs. endothelin receptor antagonism on renovascular function in liquorice-induced hypertension. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20011101 |
Life-threatening hyperkalemia during combined therapy with angiotensin-converting enzyme inhibitors and spironolactone. | The American journal of medicine 20011101 |
Blood pressure responses to small doses of amiloride and spironolactone in normotensive subjects. | Hypertension (Dallas, Tex. : 1979) 20011101 |
Treatment of congestive heart failure: interfering the aldosterone-cardiac extracellular matrix relationship. | Hypertension (Dallas, Tex. : 1979) 20011101 |
A bioactive spirolactone iridoid and triterpenoids from Himatanthus sucuuba. | Chemical & pharmaceutical bulletin 20011101 |
Acne. Myths and management issues. | Australian family physician 20011101 |
Insulin and mineralocorticoids influence on extrarenal potassium metabolism in chronic hemodialysis patients. | Renal failure 20011101 |
Spironolactone prescribing in heart failure: comparison between general medical patients and those attending a specialist left ventricular dysfunction clinic. | The Ulster medical journal 20011101 |
Evidence for a mineralocorticoid-like receptor linked to branchial chloride cell proliferation in freshwater rainbow trout. | The Journal of experimental biology 20011101 |
The endothelin-aldosterone axis and cardiovascular diseases. | Journal of cardiovascular pharmacology 20011101 |
Treatment of heart failure: state of the art and prospectives. | Journal of cardiovascular pharmacology 20011101 |
Test and teach. Surgically correctable hypertension. Conn's syndrome and spironolactone bodies. | Pathology 20011101 |
Report from the 94th Cardiovascular and Renal Drugs Advisory Committee Meeting, October 11, 2001. | Circulation 20011030 |
Intracerebroventricular administration of a glucocorticoid receptor antagonist enhances the cardiovascular responses to brief restraint stress. | European journal of pharmacology 20011026 |
Spironolactone in left-sided heart failure: how does it fit in? | American family physician 20011015 |
Information from your family doctor. What should I know about heart failure? | American family physician 20011015 |
Nongenomic regulation of ENaC by aldosterone. | American journal of physiology. Cell physiology 20011001 |
Aldosterone increases T-type calcium currents in human adrenocarcinoma (H295R) cells by inducing channel expression. | Endocrinology 20011001 |
Hyperaldosteronism: recent concepts, diagnosis, and management. | Postgraduate medical journal 20011001 |
Should an abnormal serum potassium concentration be considered a correctable cause of cardiac arrest? | Journal of the American College of Cardiology 20011001 |
Aldosterone 2001. | Trends in endocrinology and metabolism: TEM 20011001 |
Spironolactone and captopril attenuates isoproterenol-induced cardiac remodelling in rats. | Pharmacological research 20011001 |
Involvement of brain mineralocorticoid receptor in salt-enhanced hypertension in spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20011001 |
[Chronic heart failure in children: recent contributions of physiopathology and therapeutic implications]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20011001 |
Gitelman's syndrome first diagnosed as Bartter's syndrome. | Internal medicine (Tokyo, Japan) 20011001 |
Recent onset severe hypertension requiring multiple antihypertensive medications. | American journal of hypertension 20011001 |
Effects of beta-blocker therapy in severe chronic heart failure. | The New England journal of medicine 20010927 |
Spironolactone in addition to ACE inhibition to reduce proteinuria in patients with chronic renal disease. | The New England journal of medicine 20010920 |
Guideline for the management of heart failure caused by systolic dysfunction: part II. Treatment. | American family physician 20010915 |
Spironolactone reduces cerebral infarct size and EGF-receptor mRNA in stroke-prone rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20010901 |
Trans-tubular potassium gradient in patients with drug-induced hyperkalemia. | Nephron 20010901 |
Comparison of two oral electrolyte solutions for the treatment of dehydrated calves with experimentally-induced diarrhoea. | Veterinary journal (London, England : 1997) 20010901 |
Hyperkalemia, renal failure, and converting-enzyme inhibition: an overrated connection. | Hypertension (Dallas, Tex. : 1979) 20010901 |
Mediators of chronic heart failure: how drugs work. | The Annals of pharmacotherapy 20010901 |
Brain natriuretic peptide-guided therapy for heart failure. | Annals of medicine 20010901 |
[New gestagens--advantages and disadvantages]. | Therapeutische Umschau. Revue therapeutique 20010901 |
Hormones and acne: pathophysiology, clinical evaluation, and therapies. | Seminars in cutaneous medicine and surgery 20010901 |
Ovarian cyst in a premature infant treated with spironolactone. | American journal of perinatology 20010901 |
Effect of spironolactone on cisplatin-induced nephrotoxicity in rabbits. | Human & experimental toxicology 20010901 |
[Treatment of ascites in cirrhotic patients]. | Anales del sistema sanitario de Navarra 20010901 |
Aldosterone mediates the changes in hexose transport induced by low sodium intake in chicken distal intestine. | The Journal of physiology 20010815 |
Effect of a selective aldosterone receptor antagonist in myocardial infarction. | American journal of physiology. Heart and circulatory physiology 20010801 |
Aldosterone as a determinant of cardiovascular and renal dysfunction. | Journal of the Royal Society of Medicine 20010801 |
The effect of antihypertensive drugs on vascular compliance. | Current hypertension reports 20010801 |
A family with liddle's syndrome caused by a mutation in the beta subunit of the epithelial sodium channel. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20010801 |
Spironolactone-induced hepatitis. | The Australasian journal of dermatology 20010801 |
Torsade de pointes with a normal QT interval associated with hypokalemia: a case report. | Japanese circulation journal 20010801 |
Successful long-term treatment of refractory Cushing's disease with high-dose mifepristone (RU 486). | The Journal of clinical endocrinology and metabolism 20010801 |
Practical recommendations for the use of ACE inhibitors, beta-blockers and spironolactone in heart failure: putting guidelines into practice. | European journal of heart failure 20010801 |
[Torasemide (LUPRAC): a review of its pharmacological and clinical profile]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010801 |
Exciting new drugs on the horizon - eplerenone, a selective aldosterone receptor antagonist (SARA). | International journal of cardiology 20010801 |
Anthracycline-induced cardiomyopathy. | Seminars in oncology 20010801 |
Effects of different steroid-biosynthesis inhibitors on the testicular steroidogenesis of the toad Bufo arenarum. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010801 |
[Cost effectiveness of the use of spironolactone in the treatment of chronic heart failure]. | Anales de medicina interna (Madrid, Spain : 1984) 20010801 |
Long-term therapy with spironolactone. | Pharmacy world & science : PWS 20010801 |
Adrenal cortical carcinoma. | Current treatment options in oncology 20010801 |
Manipulation of the renin-angiotensin system. | Circulation 20010731 |
Cautions over idiopathic aldosteronism. | Lancet (London, England) 20010728 |
Eplerenone suppresses constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries. | Circulation 20010724 |
Aldosterone induces angiotensin-converting-enzyme gene expression in cultured neonatal rat cardiocytes. | Circulation 20010710 |
Loop diuretic infusion increases thiazide-sensitive Na(+)/Cl(-)-cotransporter abundance: role of aldosterone. | Journal of the American Society of Nephrology : JASN 20010701 |
Psychological stress increases hippocampal mineralocorticoid receptor levels: involvement of corticotropin-releasing hormone. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010701 |
Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats. | British journal of pharmacology 20010701 |
Genotype/phenotype observations in African Americans with Bartter syndrome. | The Journal of pediatrics 20010701 |
Amphotericin B-induced partial nephrogenic diabetes insipidus in a child. | Pediatric nephrology (Berlin, Germany) 20010701 |
Do cardiologists at a university hospital adopt the guidelines for the treatment of heart failure? | Arquivos brasileiros de cardiologia 20010701 |
Circadian variation in the effects of aldosterone blockade on heart rate variability and QT dispersion in congestive heart failure. | Journal of the American College of Cardiology 20010601 |
[Evidence based medical treatment of heart failure]. | Revista espanola de cardiologia 20010601 |
Determination and characterization of diuretics in human urine by liquid chromatography coupled to pneumatically assisted electrospray ionization mass spectrometry. | Journal of mass spectrometry : JMS 20010601 |
Disappearance of spironolactone-induced gynecomastia with triamteren. | Internal medicine (Tokyo, Japan) 20010601 |
Clinical, biochemical and molecular genetic data in five children with Gitelman's syndrome. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010601 |
Neurohumoral regulation in ischemia-induced heart failure. Role of the forebrain. | Annals of the New York Academy of Sciences 20010601 |
Acne news. | Dermatology nursing 20010601 |
Guidelines for management of patients with chronic heart failure in Australia. | The Medical journal of Australia 20010507 |
Fatal portal hypertension, liver failure, and mitochondrial dysfunction after HIV-1 nucleoside analogue-induced hepatitis and lactic acidaemia. | Lancet (London, England) 20010505 |
Antimineralocorticoid 11beta-substituted spirolactones exhibit androgen receptor agonistic activity: a structure function study. | Molecular pharmacology 20010501 |
Effects of albumin/furosemide mixtures on responses to furosemide in hypoalbuminemic patients. | Journal of the American Society of Nephrology : JASN 20010501 |
Adrenocorticosteroid receptor blockade and excitotoxic challenge regulate adrenocorticosteroid receptor mRNA levels in hippocampus. | Journal of neuroscience research 20010501 |
The spironolactone renaissance. | Expert opinion on investigational drugs 20010501 |
Effects of canrenone on aorta and right ventricle of the rat. | Journal of cardiovascular pharmacology 20010501 |
Breed and heterotic effects on postweaning traits in Altex and New Zealand White straightbred and crossbred rabbits. | Journal of animal science 20010501 |
Diane 35 and spironolactone combination in the treatment of hirsutism. | Clinical endocrinology 20010501 |
[Secondary hypertension]. | Nihon rinsho. Japanese journal of clinical medicine 20010501 |
Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure. | Cardiology clinics 20010501 |
Reducing readmissions for congestive heart failure. | American family physician 20010415 |
Life-threatening hyperkalemia during combined therapy with angiotensin-converting enzyme inhibitors and spironolactone: an analysis of 25 cases. | The American journal of medicine 20010415 |
Are we ready for pharmacogenomics in heart failure? | European journal of pharmacology 20010406 |
Serious adverse events experienced by patients with chronic heart failure taking spironolactone. | Heart (British Cardiac Society) 20010401 |
Aldosterone as a mediator of progressive renal disease: pathogenetic and clinical implications. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20010401 |
Hypokalemia, metabolic alkalosis, and hypertension: Cushing's syndrome in a patient with metastatic prostate adenocarcinoma. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20010401 |
Effect of spironolactone on plasma brain natriuretic peptide and left ventricular remodeling in patients with congestive heart failure. | Journal of the American College of Cardiology 20010401 |
Factors influencing the prediction of steady state concentrations of digoxin. | Biological & pharmaceutical bulletin 20010401 |
Glucocorticoid and mineralocorticoid receptors are involved in the facilitation of anxiety-like response induced by restraint. | Neuroendocrinology 20010401 |
Population-based investigation of relative clearance of digoxin in Japanese neonates and infants by multiple-trough screen analysis. | European journal of clinical pharmacology 20010401 |
Aldosteronoma in a dog with polyuria as the leading symptom. | Domestic animal endocrinology 20010401 |
[What is the role of hormonal treatments in acne?]. | Annales de dermatologie et de venereologie 20010401 |
Eplerenone (GD Searle & Co). | Current opinion in investigational drugs (London, England : 2000) 20010401 |
Recent studies with eplerenone, a novel selective aldosterone receptor antagonist. | Current opinion in pharmacology 20010401 |
How many medicines do patients with heart failure need? | Circulation 20010327 |
Undertreatment of heart failure has high cost to patients. | BMJ (Clinical research ed.) 20010324 |
Endogenous glucocorticoids play a positive regulatory role in the anti-keyhole limpet hemocyanin in vivo antibody response. | Journal of immunology (Baltimore, Md. : 1950) 20010315 |
Effects of converting enzyme inhibitors on renal P-450 metabolism of arachidonic acid. | American journal of physiology. Regulatory, integrative and comparative physiology 20010301 |
Modulation of transalveolar fluid absorption by endogenous aldosterone in adult rats. | Experimental lung research 20010301 |
A review of the medical treatment of primary aldosteronism. | Journal of hypertension 20010301 |
Long-term efficacy of torsemide compared with frusemide in cirrhotic patients with ascites. | Scandinavian journal of gastroenterology 20010301 |
Heart biometry and allometry in rats submitted to nitric oxide synthesis blockade and treatment with antihypertensive drugs. | Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 20010301 |
High serum level of procollagen type III amino-terminal peptide contributes to the efficacy of spironolactone and angiotensin-converting enzyme inhibitor therapy on left ventricular hypertrophy in essential hypertensive patients. | Hypertension research : official journal of the Japanese Society of Hypertension 20010301 |
[Biological factors influencing response to diuretics in patients with cirrhosis and ascites]. | Gastroenterologie clinique et biologique 20010301 |
Mineralocorticoid receptor-mediated signaling regulates the ion gated sodium channel in vascular endothelial cells and requires an intact cytoskeleton. | Biochemical and biophysical research communications 20010209 |
[Effect of aldosterone antagonism in heart failure: pharmacotherapeutic options]. | Nederlands tijdschrift voor geneeskunde 20010203 |
[Cost-benefit analysis of spironolactone use in the treatment of chronic heart failure]. | Revista espanola de cardiologia 20010201 |
Prevention of aortic and cardiac fibrosis by spironolactone in old normotensive rats. | Journal of the American College of Cardiology 20010201 |
Mineralocorticoid receptor affects AP-1 and nuclear factor-kappab activation in angiotensin II-induced cardiac injury. | Hypertension (Dallas, Tex. : 1979) 20010201 |
Aldosterone receptor antagonism normalizes vascular function in liquorice-induced hypertension. | Hypertension (Dallas, Tex. : 1979) 20010201 |
K(+) depletion and the progression of hypertensive disease or heart failure. The pathogenic role of diuretic-induced aldosterone secretion. | Hypertension (Dallas, Tex. : 1979) 20010201 |
Pharmacotherapy of systolic heart failure: emphasis on mortality outcomes. | Medicine and health, Rhode Island 20010201 |
[Effect of aldosterone on the secretion of endothelin by ventricular fibroblasts]. | Sheng li xue bao : [Acta physiologica Sinica] 20010201 |
[Medical treatment of chronic heart insufficiency]. | Annales de cardiologie et d'angeiologie 20010201 |
[The effect of aldosterone of promotion on proliferation of ventricular fibroblasts]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20010201 |
Inhibitors of type II 17beta-hydroxysteroid dehydrogenase. | Molecular and cellular endocrinology 20010122 |
A very short synthesis of steroids from 1,3-butadiene and benzocyclobutenes. | The Journal of organic chemistry 20010112 |
Quality control of inactivated erysipelas vaccines: results of an international collaborative study to establish a new regulatory test. | Vaccine 20010108 |
Direct estimation of the in vivo dissolution of spironolactone, in two particle size ranges, using the single-pass perfusion technique (Loc-I-Gut) in humans. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010101 |
Viral myocarditis and dilated cardiomyopathy: mechanisms, manifestations, and management. | Postgraduate medical journal 20010101 |
Furosemide-induced natriuresis as a test to identify cirrhotic patients with refractory ascites. | Hepatology (Baltimore, Md.) 20010101 |
Preventing acute mountain sickness. | The Journal of family practice 20010101 |
Laragh's lessons in pathophysiology and clinical pearls for treating hypertension. | American journal of hypertension 20010101 |
Preformulation experiences and in vitro model studies with spironolactone-containing suppositories. | Die Pharmazie 20010101 |
[Management of bronchiolitis in the infant. Recommendations. Long text]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20010101 |
[Innovative cell culture methods in drug development]. | ALTEX 20010101 |
[Modern drug development by molecular- and cell-biological methods]. | ALTEX 20010101 |
[Recent developments on the European ban on animal experiments for cosmetics]. | ALTEX 20010101 |
[Development of alternative methods by the EDQM and the Biological Standardization Program]. | ALTEX 20010101 |
['Replacement Methods to Animal Testing' as the incentive topic of the German Ministry of Education and Research. Selected results on biological drugs]. | ALTEX 20010101 |
[100 years of erysipelas prophylaxis: significance and reduction of animal experiments]. | ALTEX 20010101 |
[Development of in vitro methods for the potency testing of clostridial vaccines]. | ALTEX 20010101 |
[Clinical endpoints during rabies vaccine control tests]. | ALTEX 20010101 |
[A new application for the human whole blood test: development of an assay to assess the health risk of air-borne microbial contaminations]. | ALTEX 20010101 |
[Effect of the preservative thiomersal on the release of interleukin-1 beta from human peripheral blood cells]. | ALTEX 20010101 |
[Mediator release assay of rat basophil leukemia cells as alternative for passive cutaneous anaphylaxis testing (PCA) in laboratory animals]. | ALTEX 20010101 |
[In vitro models of intestinal and alveolar epithelium cultures in pharmaceutical research]. | ALTEX 20010101 |
[Good cell culture practice (GCCP)--an initiative for standardization and quality control of in vitro studies. The establishment of an ECVAM Task Force on GCCP]. | ALTEX 20010101 |
[The importance of standardised cell culture methods for the routine toxicology in pharmaceutical companies]. | ALTEX 20010101 |
[In vitro permeability studies as a substitute for in vivo studies--which requirements have to be met?]. | ALTEX 20010101 |
Twenty-Four hour blood pressure profile in subjects with different subtypes of primary aldosteronism. | Physiological research 20010101 |
A risk-benefit assessment of pharmacological therapies for hirsutism. | Drug safety 20010101 |
The suitability of hepatocyte culture models to study various aspects of drug metabolism. | ALTEX 20010101 |
Reconstructed skin equivalents for assessing percutaneous drug absorption from pharmaceutical formulations. | ALTEX 20010101 |
[Replacement of the pyrogen-test as batch control test for the biological substances aprotinin and urokinase]. | ALTEX 20010101 |
Internet laboratory for predicting harmful effects triggered by drugs and chemicals. Concept and call for co-operation. | ALTEX 20010101 |
[Report on the ICCVAM workshop on in vitro methods for assessing acute systemic toxicity]. | ALTEX 20010101 |
[In vitro methods for phototoxicity and photocarcinogenicity testing of drugs]. | ALTEX 20010101 |
Prediction of embryotoxic effects of valproic acid-derivatives with molecular in vitro methods. | ALTEX 20010101 |
[Permanent embryonic mouse germ cell-lines, an in vitro alternative to in vivo germ cell mutagenicity tests]. | ALTEX 20010101 |
[White Paper of the Commission of European Community--strategy for a future chemicals policy]. | ALTEX 20010101 |
Expression of the 11beta-hydroxysteroid dehydrogenase type II enzyme in breast tumors and modulation of activity and cell growth in PMC42 cells. | The Journal of steroid biochemistry and molecular biology 20010101 |
Primary aldosteronism: a practical approach to diagnosis and treatment. | Journal of clinical hypertension (Greenwich, Conn.) 20010101 |
[Symposium 'The dignity of animals--significance in the enrichment of human life'. Basle, March 15-16, 2001]. | ALTEX 20010101 |
[Animal experimentation and animal rights. Evangelical Academy Bad Boll, March 23-25, 2001]. | ALTEX 20010101 |
[Cosmetics--European Parliament demands marketing prohibition]. | ALTEX 20010101 |
Hirsutism: diagnosis and management. | The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia 20010101 |
New treasures from old? EPHESUS. Eplerenome Post-AHI Heart Failure Efficacy and Survival Study. | Cardiovascular drugs and therapy 20010101 |
The EPHESUS trial: eplerenone in patients with heart failure due to systolic dysfunction complicating acute myocardial infarction. Eplerenone Post-AMI Heart Failure Efficacy and Survival Study. | Cardiovascular drugs and therapy 20010101 |
[Clinical trials on heart failure]. | Revista espanola de cardiologia 20010101 |
[Periodic paralysis secondary to urinary or gastrointestinal potassium loss]. | Ryoikibetsu shokogun shirizu 20010101 |
Evaluation of a unique oral contraceptive in the treatment of premenstrual dysphoric disorder. | Journal of women's health & gender-based medicine 20010101 |
[Marker transport across biological barriers in vitro: comparison of cell culture models for the gastrointestinal barrier, the blood-brain barrier and the alveolar epithelium of the lung]. | ALTEX 20010101 |
Campylobacter fetus diagnosis: direct immunofluorescence comparing chicken IgY and rabbit IgG conjugates. | ALTEX 20010101 |
[Evaluation of authorised experiments on laboratory animals with regard to the aim of the research to be carried out, its scientific usefulness and its medical relevance]. | ALTEX 20010101 |
[Letter to the Editor]. | ALTEX 20010101 |
[The new EU politics of chemicals: chance for animal research-free procedures or a common grave for millions of laboratory animals?]. | ALTEX 20010101 |
[Mutant mice and world-wide damage--the most complicated way in the wrong direction]. | ALTEX 20010101 |
Eplerenone: a selective aldosterone receptor antagonist (SARA). | Cardiovascular drug reviews 20010101 |
Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne. | The Cochrane database of systematic reviews 20010101 |
Population pharmacokinetics of digoxin in Japanese patients: a 2-compartment pharmacokinetic model. | Clinical pharmacokinetics 20010101 |
Effects of spironolactone and fosinopril on the spontaneous and chronic ventricular arrhythmias in a rat model of myocardial infarction. | Cardiology 20010101 |
[Ethical aspects of man and commerce(Literary overview 2000/2001) Literature report on the new approach of the Archives on ethics toward animals, nature and the environment]. | ALTEX 20010101 |
[The laboratory animal - measuring device and/or fellow-creature?]. | ALTEX 20010101 |
[Establishment of an in vitro model for rheumatoid arthritis as test system for therapeutical substances]. | ALTEX 20010101 |
White paper on the future chemical policy in the European Union - implications for animal welfare. | ALTEX 20010101 |
[The new threshold in animal welfare--what will it bring to animals?]]. | ALTEX 20010101 |
What is the optimal medical management of ischaemic heart failure? | British medical bulletin 20010101 |
Some thyrotropic agents. | IARC monographs on the evaluation of carcinogenic risks to humans 20010101 |
Effect of phenobarbital and spironolactone treatment on the oxidative metabolism of antipyrine by rat liver microsomes. | Polish journal of pharmacology 20010101 |
Three Rs potential in the development and quality control of pharmaceuticals. | ALTEX 20010101 |
Three Rs potential in the development and quality control of immunobiologicals. | ALTEX 20010101 |
Portal hypertension. Update on pathophysiology and management. | Le Journal medical libanais. The Lebanese medical journal 20010101 |
Spironolactone for heart failure: a worthy addition to therapy. | Advance for nurse practitioners 20010101 |
Induction of cardiac fibrosis by aldosterone. | Journal of molecular and cellular cardiology 20000601 |
The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. | The New England journal of medicine 19990902 |
Rapid and sensitive reporter gene assays for detection of antiandrogenic and estrogenic effects of environmental chemicals. | Toxicology and applied pharmacology 19990301 |
Adrenocorticotrophin-induced hypertension: effects of mineralocorticoid and glucocorticoid receptor antagonism. | Journal of hypertension 19990301 |
Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element. | Molecular pharmacology 19981201 |
Do diuretics differ in terms of clinical outcome in congestive heart failure? | European heart journal 19981201 |
Effects of spironolactone on exercise capacity and neurohormonal factors in patients with heart failure treated with loop diuretics and angiotensin-converting enzyme inhibitor. | General pharmacology 19980701 |
The role of blood pressure and aldosterone in the production of hemorrhagic stroke in captopril-treated hypertensive rats. | Stroke 19970901 |
Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients. | Cardiovascular research 19970701 |
[The clinical spectrum of potassium-sparing diuretics]. | Praxis 19970402 |
Cognitive dysfunctions induced by scopolamine are reduced by systemic or intrahippocampal mineralocorticoid receptor blockade. | Pharmacology, biochemistry, and behavior 19970401 |
[Type 4 renal tubular acidosis caused by spironolactone. A case report]. | Minerva medica 19970301 |
Dose-response relationships and mineralocorticoid activity in cortisol-induced hypertension in humans. | Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19961201 |
New activity of spironolactone. Inhibition of angiogenesis in vitro and in vivo. | Circulation 19961115 |
Acute renal failure induced by angiotensin converting enzyme inhibitor in a patient with polyarteritis nodosa. | Renal failure 19960301 |
Drug-induced gynecomastia. | Pharmacotherapy 19930101 |
The effects of enalapril and spironolactone on terbutaline-induced hypokalemia. | Chest 19920701 |
Hypokalemic and ECG sequelae of combined beta-agonist/diuretic therapy. Protection by conventional doses of spironolactone but not triamterene. | Chest 19901001 |
Nephrocalcinosis and phosphate supplementation in a preterm infant. | Acta paediatrica Scandinavica 19901001 |
Reversal of lithium-related cardiac repolarization delay by potassium. | Journal of clinical psychopharmacology 19900801 |
Spironolactone versus nifedipine in essential hypertension. | The American journal of cardiology 19900619 |
[Severe complications during enalapril therapy for heart insufficiency]. | Schweizerische medizinische Wochenschrift 19881203 |
Mineral excretion in premature infants receiving various diuretic therapies. | The Journal of pediatrics 19880901 |
Topical spironolactone inhibits dihydrotestosterone receptors in human sebaceous glands: an autoradiographic study in subjects with acne vulgaris. | International journal of tissue reactions 19880101 |
[Acute reversible kidney insufficiency due to enalapril during diuretic-treated heart insufficiency]. | Deutsche medizinische Wochenschrift (1946) 19870612 |
Arrhythmogenic potential of diuretic induced hypokalaemia in patients with mild hypertension and ischaemic heart disease. | British heart journal 19850901 |
[A successfully treated case of spironolactone-induced hyperkalemic quadriplegia]. | Orvosi hetilap 19850811 |
Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics. | Journal of cardiovascular pharmacology 19850101 |
Use of a bioassay in healthy men to evaluate diuretic-spironolactone combinations. | British journal of clinical pharmacology 19830501 |
Massive pulmonary embolism occurring with corticosteroid and diuretics therapy in a minimal-change nephrotic patient. | Nephron 19820101 |
Spironolactone hepatitis in primary hyperaldosteronism. | Annals of internal medicine 19811201 |
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients. | Clinical pharmacology and therapeutics 19800401 |
Hyperkalaemic paralysis due to spironolactone. | Postgraduate medical journal 19800401 |
The occurrence of hyperaldosteronism in infants with congestive heart failure. | The American journal of cardiology 19800201 |
Clinical and biochemical effects of spironolactone administered once daily in primary hypertension. Multicenter Sweden study. | Hypertension (Dallas, Tex. : 1979) 19800101 |
Renin-secreting tumor. Case report. | Hypertension (Dallas, Tex. : 1979) 19800101 |
Pituitary-thyroid function in spironolactone treated hypertensive women. | Acta endocrinologica 19790401 |
Comparison of natriuretic, uricosuric, and antihypertensive properties of tienilic acid, bendrofluazide, and spironolactone. | British medical journal 19790127 |
Maintenance of potassium balance during diuretic therapy. | Acta medica Scandinavica 19790101 |
The relative potency of amiloride and spironolactone in bendrofluazide-treated hypertensive patients [proceedings]. | British journal of clinical pharmacology 19781101 |
[Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)]. | Deutsche medizinische Wochenschrift (1946) 19781020 |
Estrogens and hypertension: effect of discontinuing estrogens on blood pressure, exchangeable sodium, and the renin-aldosterone system. | The American journal of the medical sciences 19780101 |
Plasma potassium in hypertensive Africans on frusemide. | The Journal of international medical research 19780101 |
[Cholestatic hepatitis due to ajmaline. Lymphatic congestion of the liver. Recovery after spironolactone]. | Medecine & chirurgie digestives 19780101 |
[Hyperammonemia and hepatic encephalopathy in cirrhotics receiving spironolactone (author's transl)]. | La Nouvelle presse medicale 19771105 |
[Aldactone in the treatment of sarcoidosis of the lungs (author's transl)]. | Zeitschrift fur Erkrankungen der Atmungsorgane 19770701 |
Mineralocorticoid hypertension in childhood. | Mayo Clinic proceedings 19770501 |
Inhibition of frusemide-induced natriuresis by indomethacin in patients with the nephrotic syndrome. | Clinical science and molecular medicine 19770201 |
Spironolactone-associated aggravation of renal functional impairment. | The New Zealand medical journal 19760310 |
Renin concentrations and effects of propranolol and spironolactone in patients with hypertension. | British medical journal 19760131 |
Intrapatient comparison of treatment with chlorthalidone, spironolactone and propranolol in normoreninemic essential hypertension. | The American journal of cardiology 19751031 |
Antihypertensive action of indapamide. Comparative studies in several experimental models. | Arzneimittel-Forschung 19751001 |
Spironolactone metabolism in man studied by gas chromatography-mass spectrometry. | Drug metabolism and disposition: the biological fate of chemicals 19750101 |
The influence of aldosterone and anticonvulsant drugs on electroencephalographic and clinical disturbances induced by the spirolactone derivative, potassium canrenoate. | Journal of the neurological sciences 19750101 |
Effect of microsomal enzyme inducers on the biliary excretion of cardiac glycosides. | The Journal of pharmacology and experimental therapeutics 19741101 |
Inability of potassium canrenoate to convert experimentally induced ouabain arrhythmias in the canine heart. | Circulation research 19740501 |
Iatrogenic hyperkalemic paralysis with electrocardiographic changes. | Southern medical journal 19740301 |
Adverse reactions to spironolactone. A report from the Boston Collaborative Drug Surveillance Program. | JAMA 19730702 |
[Treatment of essential hypertension with spironolactone with reference to the plasma renin activity]. | Wiener klinische Wochenschrift 19730608 |
Gynecomastia and impotence: complications of spironolactone therapy. | JAMA 19730101 |
Spironolactone-induced hypercalciuria. | The Journal of laboratory and clinical medicine 19720801 |
Prevention and abolition of ouabain-induced ventricular tachycardia by potassium canrenoate in dogs. | European journal of pharmacology 19720801 |
Protection by spironolactone and oxandrolone against chronic digitoxin or indomethacin intoxication. | Toxicology and applied pharmacology 19710301 |
Possible mechanism of the prevention of digitoxin toxicity by spironolactone in the mouse. | Archives internationales de pharmacodynamie et de therapie 19710101 |
[Spironolactone protection against experimental cardiopathy due to digitoxin, disodium phosphate and oil]. | Pathologie-biologie 19700201 |
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