Home Carboxys Pyrrolidine-1-carboxylic acid amide

Pyrrolidine-1-carboxylic acid amide

CAS No.:
4736-71-4
Catalog Number:
AG00DIG0
Molecular Formula:
C5H10N2O
Molecular Weight:
114.1457
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
95%
1 week
United States
$244
- +
1g
95%
1 week
United States
$552
- +
Product Description
Catalog Number:
AG00DIG0
Chemical Name:
Pyrrolidine-1-carboxylic acid amide
CAS Number:
4736-71-4
Molecular Formula:
C5H10N2O
Molecular Weight:
114.1457
MDL Number:
MFCD00509172
IUPAC Name:
pyrrolidine-1-carboxamide
InChI:
InChI=1S/C5H10N2O/c6-5(8)7-3-1-2-4-7/h1-4H2,(H2,6,8)
InChI Key:
LCDCPQHFCOBUEF-UHFFFAOYSA-N
SMILES:
NC(=O)N1CCCC1
NSC Number:
117254
Properties
Complexity:
96.6  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
114.079g/mol
Formal Charge:
0
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
114.148g/mol
Monoisotopic Mass:
114.079g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
46.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.2  
Literature
Title Journal
Biophysical and cellular-uptake properties of mixed-sequence pyrrolidine-amide oligonucleotide mimics. Chemistry (Weinheim an der Bergstrasse, Germany) 20111216
A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types. The Biochemical journal 20110815
Neighboring pyrrolidine amide participation in thioether oxidation. Methionine as a 'hopping' site. Organic letters 20110603
Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review. Journal of pharmacy & bioallied sciences 20110101
Structural insights into substrate specificity in variants of N-acetylneuraminic Acid lyase produced by directed evolution. Journal of molecular biology 20101119
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitors. Bioorganic & medicinal chemistry letters 20100501
Discovery of potential new InhA direct inhibitors based on pharmacophore and 3D-QSAR analysis followed by in silico screening. European journal of medicinal chemistry 20090901
Drug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosis. PLoS computational biology 20090701
CoMFA based de novo design of pyrrolidine carboxamides as inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis. Journal of molecular modeling 20081001
Cyclobutane-containing alkaloids: origin, synthesis, and biological activities. The open medicinal chemistry journal 20080101
Stereospecific backbone methylation of pyrrolidine-amide oligonucleotide mimics (POM). Chemical communications (Cambridge, England) 20060407
Synthesis of the 1,6,8-trioxadispiro[4.1.5.2]tetradec-11-ene ring system present in the spirolide family of shellfish toxins and its conversion into a 1,6,8-trioxadispiro[4.1.5.2]-tetradec-9-en-12-ol via base-induced rearrangement of an epoxide. Organic & biomolecular chemistry 20041221
Synthesis and antibacterial evaluation of 1beta-methyl-2-(5-substituted heterocyclic carbamoyl)pyrrolidin-3-ylthio)carbapenem derivatives. Archiv der Pharmazie 20040701
Synthesis and absolute configuration of MQ-A3 [1-(14'-methylhexadecanoyl) pyrrolidine], a novel aliphatic pyrrolidine amide from the tropical convolvulaceous species. Bioscience, biotechnology, and biochemistry 20010201
Kinetically selective binding of single stranded RNA over DNA by a pyrrolidine-amide oligonucleotide mimic (POM). Nucleosides, nucleotides & nucleic acids 20010101
Properties