Home Carboxys 4-Hydroxyquinoline-2-carboxylic acid

4-Hydroxyquinoline-2-carboxylic acid

CAS No.:
492-27-3
Catalog Number:
AG00DZ70
Molecular Formula:
C10H7NO3
Molecular Weight:
189.1675
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
97%
In Stock USA
United States
$38
- +
5g
97%
In Stock USA
United States
$132
- +
25g
97%
In Stock USA
United States
$450
- +
100g
97%
In Stock USA
United States
$1225
- +
Product Description
Catalog Number:
AG00DZ70
Chemical Name:
4-Hydroxyquinoline-2-carboxylic acid
CAS Number:
492-27-3
Molecular Formula:
C10H7NO3
Molecular Weight:
189.1675
MDL Number:
MFCD00149476
IUPAC Name:
4-oxo-1H-quinoline-2-carboxylic acid
InChI:
InChI=1S/C10H7NO3/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9/h1-5H,(H,11,12)(H,13,14)
InChI Key:
HCZHHEIFKROPDY-UHFFFAOYSA-N
SMILES:
OC(=O)c1cc(O)c2c(n1)cccc2
EC Number:
207-751-5
UNII:
H030S2S85J
NSC Number:
58973
Properties
Complexity:
309  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
189.043g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
189.17g/mol
Monoisotopic Mass:
189.043g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
66.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.3  
Literature
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Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration. Cell 20110610
Desynchronization of multivesicular release enhances Purkinje cell output. Neuron 20110609
The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington's disease. Current biology : CB 20110607
Metabolomics reveals attenuation of the SLC6A20 kidney transporter in nonhuman primate and mouse models of type 2 diabetes mellitus. The Journal of biological chemistry 20110603
G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast. Neuropharmacology 20110601
Neuroprotective effects of a novel kynurenic acid analogue in a transgenic mouse model of Huntington's disease. Journal of neural transmission (Vienna, Austria : 1996) 20110601
Age dependency of inhibition of alpha7 nicotinic receptors and tonically active N-methyl-D-aspartate receptors by endogenously produced kynurenic acid in the brain. The Journal of pharmacology and experimental therapeutics 20110601
Peripheral administration of NR2 antagonists attenuates orofacial formalin-induced nociceptive behavior in rats. Progress in neuro-psychopharmacology & biological psychiatry 20110601
Descending facilitatory pathways from the rostroventromedial medulla mediate naloxone-precipitated withdrawal in morphine-dependent rats. The journal of pain : official journal of the American Pain Society 20110601
Time-course of kynurenic acid concentration in mouse serum following the administration of a novel kynurenic acid analog. Journal of pharmaceutical and biomedical analysis 20110601
Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats. Journal of pharmaceutical and biomedical analysis 20110601
Modulation of respiratory responses to chemoreflex activation by L-glutamate and ATP in the rostral ventrolateral medulla of awake rats. American journal of physiology. Regulatory, integrative and comparative physiology 20110601
Human kynurenine aminotransferase II--reactivity with substrates and inhibitors. The FEBS journal 20110601
Axonal failure during high frequency stimulation of rat subthalamic nucleus. The Journal of physiology 20110601
Kynurenine metabolites and migraine: experimental studies and therapeutic perspectives. Current neuropharmacology 20110601
Asymmetrical changes in lumbar sympathetic nerve activity following stimulation of the sciatic nerve in rat. Brain research 20110519
Epigenetic and inflammatory marker profiles associated with depression in a community-based epidemiologic sample. Psychological medicine 20110501
Distribution, synthesis, and absorption of kynurenic acid in plants. Planta medica 20110501
Immune system to brain signaling: neuropsychopharmacological implications. Pharmacology & therapeutics 20110501
Different inhibitory effects of kynurenic acid and a novel kynurenic acid analogue on tumour necrosis factor-α (TNF-α) production by mononuclear cells, HMGB1 production by monocytes and HNP1-3 secretion by neutrophils. Naunyn-Schmiedeberg's archives of pharmacology 20110501
The new '5-HT' hypothesis of depression: cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression. Progress in neuro-psychopharmacology & biological psychiatry 20110429
Migraine is a neuronal disease. Journal of neural transmission (Vienna, Austria : 1996) 20110401
Non-neuronal, slow GABA signalling in the ventrobasal thalamus targets δ-subunit-containing GABA(A) receptors. The European journal of neuroscience 20110401
The cardiovascular inhibition functions of hydrogen sulfide within the nucleus tractus solitarii are mediated by the activation of KATP channels and glutamate receptors mechanisms. Die Pharmazie 20110401
Preoptic-raphé connections for thermoregulatory vasomotor control. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110330
Antinociception by endogenous ligands at peripheral level. Ideggyogyaszati szemle 20110330
Quinolones: from antibiotics to autoinducers. FEMS microbiology reviews 20110301
Involvement of the purinergic system in central cardiovascular modulation at the level of the nucleus ambiguus of anaesthetized rats. Experimental physiology 20110301
Evidence for a key role of the peripheral kynurenine pathway in the modulation of anxiety- and depression-like behaviours in mice: focus on individual differences. Pharmacology, biochemistry, and behavior 20110301
Decreased Immunoreactivities and Functions of the Chloride Transporters, KCC2 and NKCC1, in the Lateral Superior Olive Neurons of Circling Mice. Clinical and experimental otorhinolaryngology 20110301
Inflammation in depression: is adiposity a cause? Dialogues in clinical neuroscience 20110301
Decreased plasma tryptophan and tryptophan/large neutral amino acid ratio in patients with neuroleptic-resistant schizophrenia: relationship to plasma cortisol concentration. Psychiatry research 20110227
Development of a microplate fluorescence assay for kynurenine aminotransferase. Analytical biochemistry 20110215
Excitatory amino acid receptors in the dorsomedial hypothalamus are involved in the cardiovascular and behavioural chemoreflex responses. Experimental physiology 20110201
Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2. British journal of pharmacology 20110201
Muscarinic inhibition of recurrent glutamatergic excitation in frog tectum column prevents NMDA receptor activation on efferent neuron. Experimental brain research 20110201
Protein kinase C modulates NMDA receptors in the myenteric plexus of the guinea pig ileum during in vitro ischemia and reperfusion. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110201
Kynurenic acid attenuates multiorgan dysfunction in rats after heatstroke. Acta pharmacologica Sinica 20110201
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Involvement of common intermediate 3-hydroxy-L-kynurenine in chromophore biosynthesis of quinomycin family antibiotics. The Journal of antibiotics 20110101
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System in biology leading to cell pathology: stable protein-protein interactions after covalent modifications by small molecules or in transgenic cells. Journal of biomedical science 20110101
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Effect of kynurenic acid on the viability of probiotics in vitro. Pharmacological reports : PR 20110101
Tryptophan degradation in women with breast cancer: a pilot study. BMC research notes 20110101
Dissecting the contribution of individual receptor subunits to the enhancement of N-methyl-d-aspartate currents by dopamine D1 receptor activation in striatum. Frontiers in systems neuroscience 20110101
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Ictal but not interictal epileptic discharges activate astrocyte endfeet and elicit cerebral arteriole responses. Frontiers in cellular neuroscience 20110101
Nitric Oxide-Soluble Guanylyl Cyclase-Cyclic GMP Signaling in the Striatum: New Targets for the Treatment of Parkinson's Disease? Frontiers in systems neuroscience 20110101
On the antioxidant properties of kynurenic acid: free radical scavenging activity and inhibition of oxidative stress. Neurotoxicology and teratology 20110101
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Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells. PloS one 20110101
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Lateral fluid percussion: model of traumatic brain injury in mice. Journal of visualized experiments : JoVE 20110101
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Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons. Molecular pain 20110101
Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats. Journal of biomedical science 20110101
The neurotropic parasite Toxoplasma gondii increases dopamine metabolism. PloS one 20110101
The human metabolic reconstruction Recon 1 directs hypotheses of novel human metabolic functions. BMC systems biology 20110101
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Effects of Kynurenine Pathway Inhibition on NAD Metabolism and Cell Viability in Human Primary Astrocytes and Neurons. International journal of tryptophan research : IJTR 20110101
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Environmental enrichment decreases GABAergic inhibition and improves cognitive abilities, synaptic plasticity, and visual functions in a mouse model of Down syndrome. Frontiers in cellular neuroscience 20110101
Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury. PloS one 20110101
Bestrophin1 Channels are Insensitive to Ethanol and Do not Mediate Tonic GABAergic Currents in Cerebellar Granule Cells. Frontiers in neuroscience 20110101
Intracisternally injected L-proline activates hypothalamic supraoptic, but not paraventricular, vasopressin-expressing neurons in conscious rats. Journal of amino acids 20110101
Indole compounds in some culinary-medicinal higher basidiomycetes from Poland. International journal of medicinal mushrooms 20110101
Kynurenic acid and kynurenine aminotransferases in retinal aging and neurodegeneration. Pharmacological reports : PR 20110101
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Retrograde endocannabinoid signaling reduces GABAergic synaptic transmission to gonadotropin-releasing hormone neurons. Endocrinology 20101201
Urinary metabonomics study in a rat model in response to protein-energy malnutrition by using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry. Molecular bioSystems 20101101
Nucleus raphe pallidus participates in midbrain-medullary cardiovascular sympathoinhibition during electroacupuncture. American journal of physiology. Regulatory, integrative and comparative physiology 20101101
The viscerosympathetic response in rabbits is mediated by GABAergic and glutamatergic inputs into the sympathetic premotor neurons of the rostral ventrolateral medulla. Experimental physiology 20101101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Changes in the plasma concentrations of D-kynurenine and kynurenic acid in rats after intraperitoneal administration of tryptophan enantiomers. Chirality 20101101
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Dopamine inhibition of glycine release in the rat trigeminal nucleus pars caudalis: possible involvement of trace amine receptors. Journal of neurochemistry 20100901
Aiming drug discovery at lysophosphatidic acid targets. British journal of pharmacology 20100901
Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia. Dialogues in clinical neuroscience 20100901
Crystal structure-based selective targeting of the pyridoxal 5'-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement. Journal of medicinal chemistry 20100812
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Kynurenines, neurodegeneration and Alzheimer's disease. Journal of cellular and molecular medicine 20100801
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Protective effect of systemic L-kynurenine and probenecid administration on behavioural and morphological alterations induced by toxic soluble amyloid beta (25-35) in rat hippocampus. Behavioural brain research 20100711
Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100701
Evidence for coupling between steady-state and dynamic extracellular dopamine concentrations in the rat striatum. Journal of neurochemistry 20100701
Evidence for glutamate, GABA and NO in coordinating behaviour in the sponge, Ephydatia muelleri (Demospongiae, Spongillidae). The Journal of experimental biology 20100701
Munc18 and Munc13 regulate early neurite outgrowth. Biology of the cell 20100630
Peripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression. Behavioural brain research 20100626
Determination of kynurenic acid levels in rat brain microdialysis samples and changes in kynurenic acid levels induced by N-acetylaspartic acid. Biomedical chromatography : BMC 20100601
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Kynurenate derivative attenuates the nitroglycerin-induced CamKIIα and CGRP expression changes. Headache 20100501
Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling. Toxicological sciences : an official journal of the Society of Toxicology 20100501
Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder. Journal of psychiatry & neuroscience : JPN 20100501
Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry. Molecular bioSystems 20100501
GPR35 is a novel lysophosphatidic acid receptor. Biochemical and biophysical research communications 20100430
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Changes in extracellular kynurenic acid concentrations in rat prefrontal cortex after D-kynurenine infusion: an in vivo microdialysis study. Neurochemical research 20100401
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Selective excitatory actions of DNQX and CNQX in rat thalamic neurons. Journal of neurophysiology 20100401
Glutamatergic antagonism in the NTS decreases post-inspiratory drive and changes phrenic and sympathetic coupling during chemoreflex activation. Journal of neurophysiology 20100401
Simultaneous determination of serum tryptophan metabolites in patients with systemic lupus erythematosus by high performance liquid chromatography with fluorescence detection. Clinical chemistry and laboratory medicine 20100401
Cryptic color change in a crab spider (Misumena vatia): identification and quantification of precursors and ommochrome pigments by HPLC. Journal of chemical ecology 20100401
An excitatory loop with astrocytes contributes to drive neurons to seizure threshold. PLoS biology 20100401
Treatment with granulocyte-macrophage colony-stimulating factor is associated with reduced indoleamine 2,3-dioxygenase activity and kynurenine pathway catabolites in patients with severe sepsis and septic shock. Scandinavian journal of infectious diseases 20100301
Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in Schizophrenia. Schizophrenia bulletin 20100301
Excessive tryptophan catabolism along the kynurenine pathway precedes ongoing sepsis in critically ill patients. Anaesthesia and intensive care 20100301
Melatonin and elimination of kynurenines in children with Down's syndrome. Journal of pediatric endocrinology & metabolism : JPEM 20100301
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Optimization of Zn2+-containing mobile phase for simultaneous determination of kynurenine, kynurenic acid and tryptophan in human plasma by high performance liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100215
Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease. Progress in neurobiology 20100209
Haemostatic system, biochemical profiles, kynurenines and the prevalence of cardiovascular disease in peritoneally dialyzed patients. Thrombosis research 20100201
N-Methyl-D-aspartate receptor antagonism decreases motility and inflammatory activation in the early phase of acute experimental colitis in the rat. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100201
Structure, expression, and function of kynurenine aminotransferases in human and rodent brains. Cellular and molecular life sciences : CMLS 20100201
Urinary metabonomic study on biochemical changes in chronic unpredictable mild stress model of depression. Clinica chimica acta; international journal of clinical chemistry 20100201
A novel kynurenic acid analogue: a comparison with kynurenic acid. An in vitro electrophysiological study. Journal of neural transmission (Vienna, Austria : 1996) 20100201
Glutamatergic receptor activation in the rostral ventrolateral medulla mediates the sympathoexcitatory response to hyperinsulinemia. Hypertension (Dallas, Tex. : 1979) 20100201
Kynurenic acid in blood and bone marrow plasma of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) patients. Leukemia research 20100101
The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex. Journal of molecular neuroscience : MN 20100101
Two opposite effects of Delta(9)-tetrahydrocannabinol on subthalamic nucleus neuron activity: involvement of GABAergic and glutamatergic neurotransmission. Synapse (New York, N.Y.) 20100101
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Intracisternal administration of NR2 antagonists attenuates facial formalin-induced nociceptive behavior in rats. Journal of orofacial pain 20100101
Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression. Malaria journal 20100101
Kynurenine pathway - a new link between endothelial dysfunction and carotid atherosclerosis in chronic kidney disease patients. Advances in medical sciences 20100101
NR2 subunits and NMDA receptors on lamina II inhibitory and excitatory interneurons of the mouse dorsal horn. Molecular pain 20100101
Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases. BMC biochemistry 20100101
Attention-deficit hyperactivity disorder (ADHD) and glial integrity: S100B, cytokines and kynurenine metabolism--effects of medication. Behavioral and brain functions : BBF 20100101
Attention-deficit hyperactivity disorder (ADHD) and glial integrity: an exploration of associations of cytokines and kynurenine metabolites with symptoms and attention. Behavioral and brain functions : BBF 20100101
What happens to olfaction without adult neurogenesis? Frontiers in neuroscience 20100101
A study of long-term potentiation in transgenic mice over-expressing mutant forms of both amyloid precursor protein and presenilin-1. Molecular brain 20100101
Kynurenine and its metabolites in Alzheimer's disease patients. Advances in medical sciences 20100101
Psychological stress-induced, IDO1-dependent tryptophan catabolism: implications on immunosuppression in mice and humans. PloS one 20100101
Circulating Antibodies to IDO/THO Pathway Metabolites in Alzheimer's Disease. International journal of Alzheimer's disease 20100101
Optical mapping of release properties in synapses. Frontiers in neural circuits 20100101
Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus. Molecular brain 20100101
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Evidence of fast serotonin transmission in frog slowly adapting type 1 responses. Somatosensory & motor research 20100101
Role of ionotropic GABA, glutamate and glycine receptors in the tonic and reflex control of cardiac vagal outflow in the rat. BMC neuroscience 20100101
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Microbial and bioconversion production of D-xylitol and its detection and application. International journal of biological sciences 20100101
GABA(B) Mediated Regulation of Sympathetic Preganglionic Neurons: Pre- and Postsynaptic Sites of Action. Frontiers in neurology 20100101
Drug-driven AMPA receptor redistribution mimicked by selective dopamine neuron stimulation. PloS one 20100101
GABAergic activities control spike timing- and frequency-dependent long-term depression at hippocampal excitatory synapses. Frontiers in synaptic neuroscience 20100101
NMDAR-Mediated Calcium Transients Elicited by Glutamate Co-Release at Developing Inhibitory Synapses. Frontiers in synaptic neuroscience 20100101
Molecular biology research in neuropsychiatry: India's contribution. Indian journal of psychiatry 20100101
Role of the NMDA-receptor in Prepulse Inhibition in the Rat. International journal of tryptophan research : IJTR 20100101
Endogenous Kynurenine Aminotransferases Inhibitor is Proposed to Act as 'Glia Depressing Factor' (GDF). International journal of tryptophan research : IJTR 20100101
Editorial ISTRY Special Issue. International journal of tryptophan research : IJTR 20100101
On the Biological Importance of the 3-hydroxyanthranilic Acid: Anthranilic Acid Ratio. International journal of tryptophan research : IJTR 20100101
Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder. International journal of tryptophan research : IJTR 20100101
Understanding the roles of the kynurenine pathway in multiple sclerosis progression. International journal of tryptophan research : IJTR 20100101
Alzheimer's and seizures: interleukin-18, indoleamine 2,3-dioxygenase and quinolinic Acid. International journal of tryptophan research : IJTR 20100101
Rapid Isocratic Liquid Chromatographic Separation and Quantification of Tryptophan and Six kynurenine Metabolites in Biological Samples with Ultraviolet and Fluorimetric Detection. International journal of tryptophan research : IJTR 20100101
Isolation of retinal stem cells from the mouse eye. Journal of visualized experiments : JoVE 20100101
Second-by-second analysis of alpha 7 nicotine receptor regulation of glutamate release in the prefrontal cortex of awake rats. Synapse (New York, N.Y.) 20091201
Quantum mechanics/molecular mechanics (QM/MM) modeling of the irreversible transamination of L-kynurenine to kynurenic acid: the round dance of kynurenine aminotransferase II. Biochimica et biophysica acta 20091201
Intraperiaqueductal gray glycine and D-serine exert dual effects on rostral ventromedial medulla ON- and OFF-cell activity and thermoceptive threshold in the rat. Journal of neurophysiology 20091201
Determining the neurotransmitter concentration profile at active synapses. Molecular neurobiology 20091201
Modulation of propofol on the effects of blood pressure and firing activity of related neurons in the medulla. The Chinese journal of physiology 20091130
Regulation of striatal nitric oxide synthesis by local dopamine and glutamate interactions. Journal of neurochemistry 20091120
Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies. Journal of neural transmission (Vienna, Austria : 1996) 20091101
Two crossed axonal projections contribute to binaural unmasking of frequency-following responses in rat inferior colliculus. The European journal of neuroscience 20091101
Evaluation of the oscillatory interference model of grid cell firing through analysis and measured period variance of some biological oscillators. PLoS computational biology 20091101
Roles of arterial baroreceptor reflex during bezold-jarisch reflex. Current cardiology reviews 20091101
Established therapies and novel targets in the treatment of Parkinson's disease. Expert review of clinical pharmacology 20091101
Glutamate modulation of antinociception, but not tolerance, produced by morphine microinjection into the periaqueductal gray of the rat. Brain research 20091027
Establishing a physiological environment for visualized in vitro brain slice recordings by increasing oxygen supply and modifying aCSF content. Journal of neuroscience methods 20091015
Quinoline alkaloids in honey: further analytical (HPLC-DAD-ESI-MS, multidimensional diffusion-ordered NMR spectroscopy), theoretical and chemometric studies. Journal of pharmaceutical and biomedical analysis 20091015
Long-term exposure to nicotine markedly reduces kynurenic acid in rat brain--in vitro and ex vivo evidence. Toxicology and applied pharmacology 20091015
High concentration of kynurenic acid in bile and pancreatic juice. Amino acids 20091001
Kynurenine and its metabolites--kynurenic acid and anthranilic acid are associated with soluble endothelial adhesion molecules and oxidative status in patients with chronic kidney disease. The American journal of the medical sciences 20091001
The peripheral antinociceptive effects of endomorphin-1 and kynurenic acid in the rat inflamed joint model. Anesthesia and analgesia 20091001
Cloning and molecular characterization of tick kynurenine aminotransferase (HlKAT) from Haemaphysalis longicornis (Acari: Ixodidae). Parasitology research 20090901
Electrophysiological characterisation of the actions of kynurenic acid at ligand-gated ion channels. Neuropharmacology 20090901
Neuroprotective effects of probenecid in a transgenic animal model of Huntington's disease. Journal of neural transmission (Vienna, Austria : 1996) 20090901
l-kynurenine combined with probenecid and the novel synthetic kynurenic acid derivative attenuate nitroglycerin-induced nNOS in the rat caudal trigeminal nucleus. Neuropharmacology 20090901
Kinetic basis of partial agonism at NMDA receptors. Nature neuroscience 20090901
The impact of neuroimmune dysregulation on neuroprotection and neurotoxicity in psychiatric disorders--relation to drug treatment. Dialogues in clinical neuroscience 20090901
Inhibitory effects of kynurenic acid, a tryptophan metabolite, and its derivatives on cytosolic sulfotransferases. The Biochemical journal 20090827
The role of kynurenines in disorders of the central nervous system: possibilities for neuroprotection. Journal of the neurological sciences 20090815
L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning. Behavioural brain research 20090812
Cardiovascular responses to hydrogen peroxide into the nucleus tractus solitarius. American journal of physiology. Regulatory, integrative and comparative physiology 20090801
Low oxygen enhances primitive and definitive neural stem cell colony formation by inhibiting distinct cell death pathways. Stem cells (Dayton, Ohio) 20090801
Kynurenic acid triggers firm arrest of leukocytes to vascular endothelium under flow conditions. The Journal of biological chemistry 20090717
Use of quinoline alkaloids as markers of the floral origin of chestnut honey. Journal of agricultural and food chemistry 20090708
Analysis of tryptophan catabolism in HBV patients by HPLC with programmed wavelength ultraviolet detection. Clinica chimica acta; international journal of clinical chemistry 20090701
Kynurenine, quinolinic acid--the new factors linked to carotid atherosclerosis in patients with end-stage renal disease. Atherosclerosis 20090601
Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601
On the question of infectious aetiologies for multiple sclerosis, schizophrenia and the chronic fatigue syndrome and their treatment with antibiotics. Medical hypotheses 20090601
Effects of the beta-amino acid antagonist TAG on thalamocortical inhibition. Neuropharmacology 20090601
Depolarization-induced release of endocannabinoids by murine dorsal motor nucleus of the vagus nerve neurons differentially regulates inhibitory and excitatory neurotransmission. Neuropharmacology 20090601
Effect of increasing dialyzer mass transfer area coefficient and dialysate flow on clearance of protein-bound solutes: a pilot crossover trial. American journal of kidney diseases : the official journal of the National Kidney Foundation 20090601
Pregnancy decreases GABAergic inhibition of the hypothalamic paraventricular nucleus. Physiology & behavior 20090525
Reinstatement of cocaine seeking by hypocretin (orexin) in the ventral tegmental area: independence from the local corticotropin-releasing factor network. Biological psychiatry 20090515
Vesicular glutamate filling and AMPA receptor occupancy at the calyx of Held synapse of immature rats. The Journal of physiology 20090515
Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K. Journal of medicinal chemistry 20090514
Kynurenine pathway in psychosis: evidence of increased tryptophan degradation. Journal of psychopharmacology (Oxford, England) 20090501
Elevated levels of kynurenic acid change the dopaminergic response to amphetamine: implications for schizophrenia. The international journal of neuropsychopharmacology 20090501
Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring. Schizophrenia bulletin 20090501
Structure elucidation and NMR assignments of two new pyrrolidinyl quinoline alkaloids from chestnut honey. Magnetic resonance in chemistry : MRC 20090501
Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20090501
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis. Brain : a journal of neurology 20090501
beta-adrenergic enhancement of brain kynurenic acid production mediated via cAMP-related protein kinase A signaling. Progress in neuro-psychopharmacology & biological psychiatry 20090430
Alteration of kynurenic acid concentration in rat plasma following optically pure kynurenine administration: a comparative study between enantiomers. Chirality 20090401
On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo. Journal of neurochemistry 20090401
Elevated Expression of indoleamine 2,3-dioxygenase (IDO) and accumulation of kynurenic acid in the pathogenesis of STZ-induced diabetic cataract in Wistar rats. Current eye research 20090401
Time course of changes in the concentration of kynurenic acid in the brain of pentylenetetrazol-kindled rats. Brain research bulletin 20090330
GABA and nitric oxide in the PVN are involved in arterial pressure control but not in the chemoreflex responses in rats. Autonomic neuroscience : basic & clinical 20090312
GABAergic/glutamatergic-glial/neuronal interaction contributes to rapid adaptation in pacinian corpuscles. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090304
5-HT inhibition of rat insulin 2 promoter Cre recombinase transgene and proopiomelanocortin neuron excitability in the mouse arcuate nucleus. Neuroscience 20090303
Specific inhibition of kynurenate synthesis enhances extracellular dopamine levels in the rodent striatum. Neuroscience 20090303
Cerebrolysin lowers kynurenic acid formation--an in vitro study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090301
Binaural unmasking of frequency-following responses in rat amygdala. Journal of neurophysiology 20090301
More rapid and sensitive method for simultaneous determination of tryptophan and kynurenic acid by HPLC. Clinical biochemistry 20090301
[Simultaneous determination of kynurenine and kynurenic acid in serum by high performance liquid chromatography-fluorescence detection]. Se pu = Chinese journal of chromatography 20090301
Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors. Central nervous system agents in medicinal chemistry 20090301
Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses. Neuron 20090226
Effect of indoleamine dioxygenase-1 deficiency and kynurenine pathway inhibition on murine cerebral malaria. International journal for parasitology 20090201
Tonic glutamatergic input in the rostral ventrolateral medulla is increased in rats with chronic heart failure. Hypertension (Dallas, Tex. : 1979) 20090201
Astrocyte-derived kynurenic acid modulates basal and evoked cortical acetylcholine release. The European journal of neuroscience 20090201
[Neuroprotection in Parkinson's disease and other neurodegenerative disorders: preclinical and clinical findings]. Ideggyogyaszati szemle 20090130
Modulation of the sympathetic response to acute hypoxia by the caudal ventrolateral medulla in rats. The Journal of physiology 20090115
The integrity of the glycine co-agonist binding site of N-methyl-D-aspartate receptors is a functional quality control checkpoint for cell surface delivery. The Journal of biological chemistry 20090102
Presence of kynurenic acid in food and honeybee products. Amino acids 20090101
GABA signaling in the nucleus tractus solitarius sets the level of activity in dorsal motor nucleus of the vagus cholinergic neurons in the vagovagal circuit. American journal of physiology. Gastrointestinal and liver physiology 20090101
Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort. BMC gastroenterology 20090101
Pharmacological manipulation of kynurenic acid: potential in the treatment of psychiatric disorders. CNS drugs 20090101
A zebrafish retinal graded photochemical stress model. Journal of pharmacological and toxicological methods 20090101
Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice. Molecular brain 20090101
Effects of NR1 splicing on NR1/NR3B-type excitatory glycine receptors. BMC neuroscience 20090101
Sympathetic-correlated c-Fos expression in the neonatal rat spinal cord in vitro. Journal of biomedical science 20090101
Inhibitory coupling between inhibitory interneurons in the spinal cord dorsal horn. Molecular pain 20090101
Live imaging of dense-core vesicles in primary cultured hippocampal neurons. Journal of visualized experiments : JoVE 20090101
Current trends in the treatment of infantile spasms. Neuropsychiatric disease and treatment 20090101
Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes. Molecular pain 20090101
Dendrites differ from axons in patterns of microtubule stability and polymerization during development. Neural development 20090101
Major signaling pathways in migrating neuroblasts. Frontiers in molecular neuroscience 20090101
MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy. PloS one 20090101
Homeostatic plasticity of striatal neurons intrinsic excitability following dopamine depletion. PloS one 20090101
Kynurenic acid protects against the homocysteine-induced impairment of endothelial cells. Pharmacological reports : PR 20090101
Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2 promoter. PloS one 20090101
Syntheses, transformations and pharmaceutical applications of kynurenic acid derivatives. Current medicinal chemistry 20090101
Breaching the blood-brain barrier as a gate to psychiatric disorder. Cardiovascular psychiatry and neurology 20090101
Tryptophan and kynurenine levels in lenses of Wistar and accelerated-senescence OXYS rats. Molecular vision 20090101
Optogenetic Dissection of Neuronal Circuits in Zebrafish using Viral Gene Transfer and the Tet System. Frontiers in neural circuits 20090101
Kynurenine pathway metabolites in humans: disease and healthy States. International journal of tryptophan research : IJTR 20090101
Paolo guidetti. International journal of tryptophan research : IJTR 20090101
Effects of Kynurenine Pathway Metabolites on Intracellular NAD Synthesis and Cell Death in Human Primary Astrocytes and Neurons. International journal of tryptophan research : IJTR 20090101
The physiological action of picolinic Acid in the human brain. International journal of tryptophan research : IJTR 20090101
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat. Journal of psychiatric research 20081201
Induction of the kynurenine pathway by neurotropic influenza A virus infection. Journal of neuroscience research 20081201
Analysis of urinary aromatic acids by liquid chromatography tandem mass spectrometry. Biomedical chromatography : BMC 20081201
Involvement of ST1B subfamily of cytosolic sulfotransferase in kynurenine metabolism to form natriuretic xanthurenic acid sulfate. The Journal of pharmacology and experimental therapeutics 20081201
BDNF modulation of NMDA receptors is activity dependent. Journal of neurophysiology 20081201
Curiosity to kill the KAT (kynurenine aminotransferase): structural insights into brain kynurenic acid synthesis. Current opinion in structural biology 20081201
Inflammation and the glutamate system in schizophrenia: implications for therapeutic targets and drug development. Expert opinion on therapeutic targets 20081201
Treatment of Lennox-Gastaut syndrome: overview and recent findings. Neuropsychiatric disease and treatment 20081201
Functional connectivity map of retinal ganglion cells for retinal prosthesis. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20081201
The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function. The Journal of biological chemistry 20081107
Kynurenine diminishes the ischemia-induced histological and electrophysiological deficits in the rat hippocampus. Neurobiology of disease 20081101
Excess dietary salt alters angiotensinergic regulation of neurons in the rostral ventrolateral medulla. Hypertension (Dallas, Tex. : 1979) 20081101
Conductances mediating intrinsic theta-frequency membrane potential oscillations in layer II parasubicular neurons. Journal of neurophysiology 20081101
Glutamatergic inputs to the CVLM independent of the NTS promote tonic inhibition of sympathetic vasomotor tone in rats. American journal of physiology. Heart and circulatory physiology 20081001
Effect of a traditional Chinese medicine preparation Xindi soft capsule on rat model of acute blood stasis: a urinary metabonomics study based on liquid chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081001
Biophysical basis for three distinct dynamical mechanisms of action potential initiation. PLoS computational biology 20081001
Neurotoxic and neuroprotective metabolites of kynurenine in patients with renal cell carcinoma treated with interferon-alpha: course and relationship with psychiatric status. Psychiatry and clinical neurosciences 20081001
An autonomous circadian clock in the inner mouse retina regulated by dopamine and GABA. PLoS biology 20081001
Impact of microdialysis probes on vasculature and dopamine in the rat striatum: a combined fluorescence and voltammetric study. Journal of neuroscience methods 20080930
Auditory frequency-following responses in rat ipsilateral inferior colliculus. Neuroreport 20080917
Simultaneous determination of kynurenine and kynurenic acid concentrations in human serum by HPLC with dual wavelengths fluorescence detection. Clinica chimica acta; international journal of clinical chemistry 20080901
Charge compensation for NADPH oxidase activity in microglia in rat brain slices does not involve a proton current. The European journal of neuroscience 20080901
mGluR-dependent persistent firing in entorhinal cortex layer III neurons. The European journal of neuroscience 20080901
[Effect of mutation-induced excess brain concentration of intermediates of the kynurenine pathway of tryptophan metabolism on stress resistance and courtship behavior and communicative sound production in male Drosophila melanogaster]. Genetika 20080901
GABA(B) receptor-mediated presynaptic inhibition of glycinergic transmission onto substantia gelatinosa neurons in the rat spinal cord. Pain 20080831
Possible glutamatergic and lipid signalling mechanisms in ECT-induced retrograde amnesia: experimental evidence for involvement of COX-2, and review of literature. Journal of psychiatric research 20080801
Micromolar concentration of kynurenic acid in rat small intestine. Amino acids 20080801
The Janus-face kynurenic acid. Journal of neural transmission (Vienna, Austria : 1996) 20080801
The kynurenate analog SZR-72 prevents the nitroglycerol-induced increase of c-fos immunoreactivity in the rat caudal trigeminal nucleus: comparative studies of the effects of SZR-72 and kynurenic acid. Neuroscience research 20080801
Clozapine interacts with the glycine site of the NMDA receptor: electrophysiological studies of dopamine neurons in the rat ventral tegmental area. Life sciences 20080801
Release of ATP and glutamate in the nucleus tractus solitarii mediate pulmonary stretch receptor (Breuer-Hering) reflex pathway. The Journal of physiology 20080801
Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II. Bioscience reports 20080801
Imaging synaptic inhibition throughout the brain via genetically targeted Clomeleon. Brain cell biology 20080801
The pentylenetetrazole-induced activity in the hippocampus can be inhibited by the conversion of L-kynurenine to kynurenic acid: an in vitro study. Brain research bulletin 20080730
A solid-phase extraction procedure coupled to 1H NMR, with chemometric analysis, to seek reliable markers of the botanical origin of honey. Analytica chimica acta 20080714
Urinary excretory ratio of anthranilic acid/kynurenic acid as an index of the tolerable amount of tryptophan. Bioscience, biotechnology, and biochemistry 20080701
Resistance to kynurenic acid of the NMDA receptor-dependent toxicity of 3-nitropropionic acid and cyanide in cerebellar granule neurons. Brain research 20080618
Midbrain acetylcholine and glutamate receptors modulate accumbal dopamine release. Neuroreport 20080611
Cardiovascular and behavioral responses to conditioned fear after medullary raphe neuronal blockade. Neuroscience 20080602
Critical role of the rostral ventromedial medulla in early spinal events leading to chronic constriction injury neuropathy in rats. The journal of pain : official journal of the American Pain Society 20080601
Kynurenic acid attenuates MPP(+)-induced dopaminergic neuronal cell death via a Bax-mediated mitochondrial pathway. European journal of cell biology 20080601
Characterization of TioF, a tryptophan 2,3-dioxygenase involved in 3-hydroxyquinaldic acid formation during thiocoraline biosynthesis. Molecular bioSystems 20080601
A psychoneuroimmunological perspective to Emil Kraepelins dichotomy: schizophrenia and major depression as inflammatory CNS disorders. European archives of psychiatry and clinical neuroscience 20080601
Effects of the kynurenine 3-hydroxylase inhibitor Ro 61-8048 after intrastriatal injections on the severity of dystonia in the dt sz mutant. European journal of pharmacology 20080531
Glutamatergic and purinergic mechanisms on respiratory modulation in the caudal NTS of awake rats. Respiratory physiology & neurobiology 20080531
Feedback from horizontal cells to rod photoreceptors in vertebrate retina. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080528
Kynurenine pathway metabolism in human blood-brain-barrier cells: implications for immune tolerance and neurotoxicity. Journal of neurochemistry 20080501
Effects of in situ administration of excitatory amino acid antagonists on rapid microglial and astroglial reactions in rat hippocampus following traumatic brain injury. Neurological research 20080501
Functional columns in the primate prefrontal cortex revealed by optical imaging in vitro. Neuroscience research 20080501
A link between stress and depression: shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression. Stress (Amsterdam, Netherlands) 20080501
Quantal mEPSCs and residual glutamate: how horizontal cell responses are shaped at the photoreceptor ribbon synapse. The European journal of neuroscience 20080501
Neuroprotection achieved in the ischaemic rat cortex with L-kynurenine sulphate. Life sciences 20080423
Memantine increases brain production of kynurenic acid via protein kinase A-dependent mechanism. Neuroscience letters 20080418
Surface mobility of postsynaptic AMPARs tunes synaptic transmission. Science (New York, N.Y.) 20080411
Role for D-serine within the ventral tegmental area in the development of cocaine's sensitization. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080401
Indoleamine 2,3-dioxygenase-dependent tryptophan metabolites contribute to tolerance induction during allergen immunotherapy in a mouse model. The Journal of allergy and clinical immunology 20080401
Glycinergic synaptic currents in the deep cerebellar nuclei. Neuropharmacology 20080401
Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors. Experimental eye research 20080401
Aristolochic acid induced changes in the metabolic profile of rat urine. Journal of pharmaceutical and biomedical analysis 20080313
Autism-like behavioral phenotypes in BTBR T+tf/J mice. Genes, brain, and behavior 20080301
Adenosine receptor ligands protect against a combination of apoptotic and necrotic cell death in cerebellar granule neurons. Experimental brain research 20080301
Allosteric modulation of alpha 7 nicotinic receptors selectively depolarizes hippocampal interneurons, enhancing spontaneous GABAergic transmission. The European journal of neuroscience 20080301
Pharmacodynamics of memantine: an update. Current neuropharmacology 20080301
Tonic facilitation of glutamate release by glycine binding sites on presynaptic NR2B-containing NMDA autoreceptors in the rat visual cortex. Neuroscience letters 20080227
Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase. Biochemistry 20080212
Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evidence. Biochemistry 20080212
Crystal structure of human kynurenine aminotransferase II. The Journal of biological chemistry 20080208
Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia. The Journal of biological chemistry 20080208
Involvement of subthalamic nucleus in the stimulatory effect of Delta(9)-tetrahydrocannabinol on dopaminergic neurons. Neuroscience 20080206
Gephyrin selective intrabodies as a new strategy for studying inhibitory receptor clustering. Journal of molecular neuroscience : MN 20080201
Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys. Behavioural brain research 20080125
GPR35 is a functional receptor in rat dorsal root ganglion neurons. Biochemical and biophysical research communications 20080111
Inhibition of N-type calcium channels by activation of GPR35, an orphan receptor, heterologously expressed in rat sympathetic neurons. The Journal of pharmacology and experimental therapeutics 20080101
Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes. The Journal of physiology 20080101
Kynurenic acid inhibits intestinal hypermotility and xanthine oxidase activity during experimental colon obstruction in dogs. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080101
Glutamatergic neurotransmission is not essential for, but plays a modulatory role in, the production of gasping in arterially-perfused adult rat. Advances in experimental medicine and biology 20080101
The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system. PloS one 20080101
[Determination of kynurenine in serum using high performance liquid chromatography-fluorescence detection]. Se pu = Chinese journal of chromatography 20080101
[The role of stacking interactions in the mechanisms of binding of the glycine site of NMDA-receptor with antagonists and 3-hydroxykynurenine]. Biofizika 20080101
Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition. Molecular pain 20080101
COX-2 inhibition in schizophrenia and major depression. Current pharmaceutical design 20080101
Elevated intracellular chloride level in albino visual cortex neurons is mediated by Na-K-Cl co-transporter. BMC neuroscience 20080101
Differential induction of long-term potentiation in the horizontal versus columnar superficial connections to layer II cells of the entorhinal cortex. Neural plasticity 20080101
Cocaine serves as a peripheral interoceptive conditioned stimulus for central glutamate and dopamine release. PloS one 20080101
Dopaminergic suppression of synaptic transmission in the lateral entorhinal cortex. Neural plasticity 20080101
Clenbuterol enhances the production of kynurenic acid in brain cortical slices and glial cultures. Pharmacological reports : PR 20080101
Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders. Molecular brain 20080101
5-Nitro-2-(3-phenylpropylamino)benzoic acid is a GPR35 agonist. Pharmacology 20080101
Functional identification of NR2 subunits contributing to NMDA receptors on substance P receptor-expressing dorsal horn neurons. Molecular pain 20080101
A-type GABA receptor as a central target of TRPM8 agonist menthol. PloS one 20080101
The role of SK calcium-dependent potassium currents in regulating the activity of deep cerebellar nucleus neurons: a dynamic clamp study. Cerebellum (London, England) 20080101
Primary dissociated midbrain dopamine cell cultures from rodent neonates. Journal of visualized experiments : JoVE 20080101
Polymorphisms in the interleukin-10 gene cluster are possibly involved in the increased risk for major depressive disorder. BMC medical genetics 20080101
Molecular mechanisms underlying electroconvulsive therapy-induced amnestic deficits: A decade of research. Indian journal of psychiatry 20080101
Ascorbic Acid inhibits development of tolerance and dependence to opiates in mice: possible glutamatergic or dopaminergic modulation. Indian journal of pharmaceutical sciences 20080101
N-methyl-D-aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus. Journal of neuroscience research 20071201
Tryptophan, adenosine, neurodegeneration and neuroprotection. Metabolic brain disease 20071201
Role of medullary GABA, opioids, and nociceptin in prolonged inhibition of cardiovascular sympathoexcitatory reflexes during electroacupuncture in cats. American journal of physiology. Heart and circulatory physiology 20071201
Intrinsic excitability of cholinergic neurons in the rat parabigeminal nucleus. Journal of neurophysiology 20071201
Localization of metabotropic glutamate receptors in the outer plexiform layer of the goldfish retina. Cell and tissue research 20071201
Activation of rat ventral tegmental area dopamine neurons by endogenous kynurenic acid: a pharmacological analysis. Neuropharmacology 20071201
Kynurenic acid in honey from arboreal plants: MS and NMR evidence. Planta medica 20071201
The role of NMDA and non-NMDA receptors in the NTS in mediating three distinct sympathoinhibitory reflexes. Naunyn-Schmiedeberg's archives of pharmacology 20071201
The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation. Neuro endocrinology letters 20071201
Glucagon-like peptide-1 modulates synaptic transmission to identified pancreas-projecting vagal motoneurons. Peptides 20071101
N-methyl-D-aspartate receptors and amnesia in mice with depression-like state. Bulletin of experimental biology and medicine 20071101
Membrane and synaptic properties of nucleus tractus solitarius neurons projecting to the caudal ventrolateral medulla. Autonomic neuroscience : basic & clinical 20071030
Glutamate receptor blockade in the rostral ventromedial medulla reduces the force of multisegmental motor responses to supramaximal noxious stimuli. Neuroscience letters 20071022
Long-term potentiation in the hippocampal CA1 region does not require insertion and activation of GluR2-lacking AMPA receptors. Journal of neurophysiology 20071001
Altered kynurenine metabolism correlates with infarct volume in stroke. The European journal of neuroscience 20071001
The kynurenic acid hypothesis of schizophrenia. Physiology & behavior 20070910
Tryptophan breakdown pathway in bipolar mania. Journal of affective disorders 20070901
COX-2 oxidative metabolite of endocannabinoid 2-AG enhances excitatory glutamatergic synaptic transmission and induces neurotoxicity. Journal of neurochemistry 20070901
Comparative study of NMDA and AMPA/kainate receptors involved in cardiovascular inhibition produced by imidazoline-like drugs in anaesthetized rats. Experimental physiology 20070901
Hydrogen sulfide induced neuronal death occurs via glutamate receptor and is associated with calpain activation and lysosomal rupture in mouse primary cortical neurons. Neuropharmacology 20070901
Impact of intertrigeminal region AMPA receptor blockade on respiratory responses in rats. Respiratory physiology & neurobiology 20070815
Dopamine receptor activation reveals a novel, kynurenate-sensitive component of striatal N-methyl-D-aspartate neurotoxicity. Neuroscience 20070810
Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits. The Journal of pharmacology and experimental therapeutics 20070801
Glutamate-induced calcium transients in rat neurons of the dorsal motor nucleus of the vagus. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20070801
The neurochemically diverse intermedius nucleus of the medulla as a source of excitatory and inhibitory synaptic input to the nucleus tractus solitarii. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070801
Corelease of GABA/glycine in lamina-X of the spinal cord of neonatal rats. Neuroreport 20070702
Role of ventrolateral medulla in generating the 10-Hz rhythm in sympathetic nerve discharge. American journal of physiology. Regulatory, integrative and comparative physiology 20070701
Cross-sample entropy statistic as a measure of complexity and regularity of renal sympathetic nerve activity in the rat. Experimental physiology 20070701
Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain. Journal of neurochemistry 20070701
Competitive antagonism between the nicotinic allosteric potentiating ligand galantamine and kynurenic acid at alpha7* nicotinic receptors. The Journal of pharmacology and experimental therapeutics 20070701
Activation of paraventricular nucleus neurones by the dorsomedial hypothalamus via a tachykinin pathway in rats. Experimental physiology 20070701
Excitatory regulation of noradrenergic neurons by L-arginine/nitric oxide pathway in the rat locus coeruleus in vivo. Naunyn-Schmiedeberg's archives of pharmacology 20070701
Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070701
Antinociceptive interactions of triple and quadruple combinations of endogenous ligands at the spinal level. Brain research 20070625
Involvement of L-glutamate and ATP in the neurotransmission of the sympathoexcitatory component of the chemoreflex in the commissural nucleus tractus solitarii of awake rats and in the working heart-brainstem preparation. The Journal of physiology 20070615
Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders. Journal of the neurological sciences 20070615
Neuroprotective effect of L-kynurenine sulfate administered before focal cerebral ischemia in mice and global cerebral ischemia in gerbils. European journal of pharmacology 20070614
Auto-inhibition of rat parallel fibre-Purkinje cell synapses by activity-dependent adenosine release. The Journal of physiology 20070601
SNAP and SIN-1 increase brain production of kynurenic acid. European journal of pharmacology 20070601
Temporal and mechanistic dissociation of ATP and adenosine release during ischaemia in the mammalian hippocampus. Journal of neurochemistry 20070601
[Stacking-interactions in the control-gear binding of kynurenic acid with NR2A- and GluR2-subunits of glutamate ionotropic receptors]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20070601
Prevention of electrical stimulation-induced increase of c-fos immunoreaction in the caudal trigeminal nucleus by kynurenine combined with probenecid. Neuroscience letters 20070517
Midbrain modulation of the cardiac baroreflex involves excitation of lateral parabrachial neurons in the rat. Brain research 20070511
The descending motorcortical pathway to the laryngeal motoneurons in the squirrel monkey. Brain research 20070507
Elevations of endogenous kynurenic acid produce spatial working memory deficits. Schizophrenia bulletin 20070501
Determination of rat brain kynurenic acid by column-switching HPLC with fluorescence detection. Biomedical chromatography : BMC 20070501
D-serine relieves chronic lead exposure-impaired long-term potentiation in the CA1 region of the rat hippocampus in vitro. Neuroscience letters 20070501
Toxoplasma gondii and schizophrenia: linkage through astrocyte-derived kynurenic acid? Schizophrenia bulletin 20070501
Intrathecally administered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site. Journal of pharmacological sciences 20070501
Kynurenic acid blocks nicotinic synaptic transmission to hippocampal interneurons in young rats. The European journal of neuroscience 20070501
Peripheral kynurenine metabolism in focal dystonia. Medicinal chemistry (Shariqah (United Arab Emirates)) 20070501
Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity. The European journal of neuroscience 20070501
Effects of intertrigeminal region NMDA and non-NMDA receptors on respiratory responses in rats. Respiratory physiology & neurobiology 20070416
AT(1) and glutamatergic receptors in paraventricular nucleus support blood pressure during water deprivation. American journal of physiology. Regulatory, integrative and comparative physiology 20070401
Inhibitory input from slowly adapting lung stretch receptors to retrotrapezoid nucleus chemoreceptors. The Journal of physiology 20070401
Glutamatergic inputs in the hypothalamic paraventricular nucleus maintain sympathetic vasomotor tone in hypertension. Hypertension (Dallas, Tex. : 1979) 20070401
Effects of sleep deprivation on neural functioning: an integrative review. Cellular and molecular life sciences : CMLS 20070401
Correlated species differences in the effects of cannabinoid ligands on anxiety and on GABAergic and glutamatergic synaptic transmission. The European journal of neuroscience 20070401
Development of a column-switching high-performance liquid chromatography for kynurenine enantiomers and its application to a pharmacokinetic study in rat plasma. Analytica chimica acta 20070321
Perinatal kynurenine 3-hydroxylase inhibition in rodents: pathophysiological implications. Journal of neuroscience research 20070301
Characterisation of the human NMDA receptor subunit NR3A glycine binding site. Neuropharmacology 20070301
Spectrofluorometric determination of kynurenic acid with horseradish peroxidase in the presence of hydrogen peroxide. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070301
[Role of glutamate receptors in the spiral ganglion neuron damage induced by acoustic noise]. Sheng li xue bao : [Acta physiologica Sinica] 20070225
Functional and anatomical connection between the paraventricular nucleus of the thalamus and dopamine fibers of the nucleus accumbens. The Journal of comparative neurology 20070220
Determination of kynurenine levels in rat plasma by high-performance liquid chromatography with pre-column fluorescence derivatization. Analytica chimica acta 20070219
Long-term recording on multi-electrode array reveals degraded inhibitory connection in neuronal network development. Biosensors & bioelectronics 20070215
Kynurenine pathway in major depression: evidence of impaired neuroprotection. Journal of affective disorders 20070201
Heterologous expression and purification of kynurenine-3-monooxygenase from Pseudomonas fluorescens strain 17400. Protein expression and purification 20070201
Exercise training attenuates increases in lumbar sympathetic nerve activity produced by stimulation of the rostral ventrolateral medulla. Journal of applied physiology (Bethesda, Md. : 1985) 20070201
Vasopressin autoreceptors and nitric oxide-dependent glutamate release are required for somatodendritic vasopressin release from rat magnocellular neuroendocrine cells responding to osmotic stimuli. Endocrinology 20070201
Determination of kynurenic acid in human serum and its correlation with the concentration of certain amino acids. Clinica chimica acta; international journal of clinical chemistry 20070201
Strain-specific nicotinic modulation of glutamatergic transmission in the CA1 field of the rat hippocampus: August Copenhagen Irish versus Sprague-Dawley. Journal of neurophysiology 20070201
Kynurenines impair energy metabolism in rat cerebral cortex. Cellular and molecular neurobiology 20070201
Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism. The FEBS journal 20070201
Glutamate regulates neurite outgrowth of cultured descending brain neurons from larval lamprey. Developmental neurobiology 20070201
Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists. Bioorganic & medicinal chemistry letters 20070115
Cerebrospinal fluid kynurenic acid in male and female controls - correlation with monoamine metabolites and influences of confounding factors. Journal of psychiatric research 20070101
Acute psychotic symptoms in HIV-1 infected patients are associated with increased levels of kynurenic acid in cerebrospinal fluid. Brain, behavior, and immunity 20070101
Kynurenine in combination with probenecid mitigates the stimulation-induced increase of c-fos immunoreactivity of the rat caudal trigeminal nucleus in an experimental migraine model. Journal of neural transmission (Vienna, Austria : 1996) 20070101
Central efferent pathways mediating skin cooling-evoked sympathetic thermogenesis in brown adipose tissue. American journal of physiology. Regulatory, integrative and comparative physiology 20070101
Kynurenic acid leads, dopamine follows: a new case of volume transmission in the brain? Journal of neural transmission (Vienna, Austria : 1996) 20070101
Paraventricular nucleus influence on renal sympathetic activity in vasopressin gene-deleted rats. Experimental physiology 20070101
Decreased serum and red blood cell kynurenic acid levels in Alzheimer's disease. Neurochemistry international 20070101
Astrocytic localization of kynurenine aminotransferase II in the rat brain visualized by immunocytochemistry. Glia 20070101
Glycine binding sites of presynaptic NMDA receptors may tonically regulate glutamate release in the rat visual cortex. Journal of neurophysiology 20070101
Integrative hypothesis for Huntington's disease: a brief review of experimental evidence. Physiological research 20070101
Prokineticin 2 depolarizes paraventricular nucleus magnocellular and parvocellular neurons. The European journal of neuroscience 20070101
Elevated concentrations of kynurenic acid, a tryptophan derivative, in dense nuclear cataracts. Current eye research 20070101
Astrocytic activation in relation to inflammatory markers during clinical exacerbation of relapsing-remitting multiple sclerosis. Journal of neural transmission (Vienna, Austria : 1996) 20070101
Possible glutaminergic interaction between the capsule and neurite of Pacinian corpuscles. Somatosensory & motor research 20070101
Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain. PloS one 20070101
Hyperglycemia enhances the inhibitory effect of mitochondrial toxins and D,L-homocysteine on the brain production of kynurenic acid. Pharmacological reports : PR 20070101
The immunological basis of glutamatergic disturbance in schizophrenia: towards an integrated view. Journal of neural transmission. Supplementum 20070101
Kynurenines, redox disturbances and neurodegeneration in multiple sclerosis. Journal of neural transmission. Supplementum 20070101
Ionotropic glutamate receptor activation increases intracellular calcium in prolactin-releasing cells of the adenohypophysis. American journal of physiology. Endocrinology and metabolism 20061201
Endogenous activation of nicotinic receptors underlies sympathetic tone generation in neonatal rat spinal cord in vitro. Neuropharmacology 20061201
Functional convergence of neurons generated in the developing and adult hippocampus. PLoS biology 20061201
In vitro peroxynitrite scavenging activity of 6-hydroxykynurenic acid and other flavonoids from Gingko biloba yellow leaves. Archives of pharmacal research 20061201
Role of the medial prefrontal cortex in cardiovascular responses to acute restraint in rats. Neuroscience 20061117
Central chemoreceptors and sympathetic vasomotor outflow. The Journal of physiology 20061115
Potentiation of mouse vagal afferent mechanosensitivity by ionotropic and metabotropic glutamate receptors. The Journal of physiology 20061115
The sympathoinhibitory effects of systemic cholecystokinin are dependent on neurons in the caudal ventrolateral medulla in the rat. American journal of physiology. Regulatory, integrative and comparative physiology 20061101
Contribution of endogenous glycine site NMDA agonists to excitotoxic retinal damage in vivo. Neuroscience research 20061101
Modulation of the function of presynaptic alpha7 and non-alpha7 nicotinic receptors by the tryptophan metabolites, 5-hydroxyindole and kynurenate in mouse brain. British journal of pharmacology 20061101
Kynurenine pathway metabolism in patients with osteoporosis after 2 years of drug treatment. Clinical and experimental pharmacology & physiology 20061101
Subthalamic stimulation-induced forelimb dyskinesias are linked to an increase in glutamate levels in the substantia nigra pars reticulata. The Journal of neuroscience : the official journal of the Society for Neuroscience 20061018
Spikelet currents in frog tectal neurons with different firing patterns in vitro. Neuroscience letters 20061002
Chronic neuroleptic treatment reduces endogenous kynurenic acid levels in rat brain. Journal of neural transmission (Vienna, Austria : 1996) 20061001
Kynurenic acid synthesis in bovine retinal slices--effect of glutamate agonists. Journal of neural transmission (Vienna, Austria : 1996) 20061001
Differences between the scaling of miniature IPSCs and EPSCs recorded in the dendrites of CA1 mouse pyramidal neurons. The Journal of physiology 20061001
Schizophrenia as an inflammation-mediated dysbalance of glutamatergic neurotransmission. Neurotoxicity research 20061001
Inflammation and depression: is there a causal connection with dementia? Neurotoxicity research 20061001
Disinhibition of the cardiac limb of the arterial baroreflex in rat: a role for metabotropic glutamate receptors in the nucleus tractus solitarii. The Journal of physiology 20060915
Activation of lateral parabrachial nucleus neurons restores blood pressure and sympathetic vasomotor drive after hypotensive hemorrhage. American journal of physiology. Regulatory, integrative and comparative physiology 20060901
Role of glutamate in a visceral sympathoexcitatory reflex in rostral ventrolateral medulla of cats. American journal of physiology. Heart and circulatory physiology 20060901
Glutamate receptors in the raphe pallidus mediate brown adipose tissue thermogenesis evoked by activation of dorsomedial hypothalamic neurons. Neuropharmacology 20060901
Activation of metabotropic glutamate receptors induces propagating network oscillations in the intact cerebral cortex of the newborn mouse. Neuropharmacology 20060901
Interferon-induced depressive illness in hep C patients responds to SSRI antidepressant treatments. Neuropsychiatric disease and treatment 20060901
Tryptophan metabolism in the central nervous system: medical implications. Expert reviews in molecular medicine 20060831
Chronic hypobaric hypoxia induces tolerance to acute hypoxia and up-regulation in alpha-2 adrenoceptor in rat locus coeruleus. Brain research 20060823
Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. The Journal of biological chemistry 20060804
A metabolomic approach to ionotropic glutamate receptor subtype function: a nuclear magnetic resonance in vitro investigation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060801
Elevated T-maze evaluation of anxiety and memory effects of NMDA/glycine-B site ligands injected into the dorsal periaqueductal gray matter and the superior colliculus of rats. Neuropharmacology 20060801
Effect of 6-hydroxydopamine treatment on kynurenine aminotransferase-I (KAT-I) immunoreactivity of neurons and glial cells in the rat substantia nigra. Acta neuropathologica 20060801
Prooxidant action of xanthurenic acid and quinoline compounds: role of transition metals in the generation of reactive oxygen species and enhanced formation of 8-hydroxy-2'-deoxyguanosine in DNA. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20060801
Synaptic inputs to retinal ganglion cells that set the circadian clock. The European journal of neuroscience 20060801
Enhancement of brain kynurenic acid production by anticonvulsants--novel mechanism of antiepileptic activity? European journal of pharmacology 20060717
Kynurenic acid has a dual action on AMPA receptor responses. Neuroscience letters 20060710
Ammonia at pathophysiologically relevant concentrations activates kynurenic acid synthesis in cultured astrocytes and neurons. Neurotoxicology 20060701
Activation of the caspase 8 pathway mediates seizure-induced cell death in cultured hippocampal neurons. Epilepsy research 20060701
Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice. Neurobiology of disease 20060701
The role of supraspinal vasopressin and glutamate neurones in an increase in renal sympathetic activity in response to mild haemorrhage in the rat. Experimental physiology 20060701
Taurine potentiates presynaptic NMDA receptors in hippocampal Schaffer collateral axons. The European journal of neuroscience 20060701
Increased concentration of cerebral kynurenic acid alters stimulus processing and conditioned responding. Behavioural brain research 20060630
Autonomic and respiratory responses to microinjection of L-glutamate into the commissural subnucleus of the NTS in the working heart-brainstem preparation of the rat. Brain research 20060606
Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population. Genes, brain, and behavior 20060601
4-chloro-3-hydroxyanthranilate reduces local quinolinic acid synthesis, improves functional recovery, and preserves white matter after spinal cord injury. Journal of neurotrauma 20060601
Antihypertensive responses elicited by central moxonidine in rats: possible role of nitric oxide. Journal of cardiovascular pharmacology 20060601
Changes in the immune system in depression and dementia: causal or coincidental effects? Dialogues in clinical neuroscience 20060601
Roles of the fast-releasing and the slowly releasing vesicles in synaptic transmission at the calyx of Held. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060531
Electroacupuncture improves restraint stress-induced delay of gastric emptying via central glutaminergic pathways in conscious rats. Neuroscience letters 20060515
Subchronic treatment with kynurenine and probenecid: effects on prepulse inhibition and firing of midbrain dopamine neurons. Journal of neural transmission (Vienna, Austria : 1996) 20060501
Chemoreflex sympathoexcitation was not altered by the antagonism of glutamate receptors in the commissural nucleus tractus solitarii in the working heart-brainstem preparation of rats. Experimental physiology 20060501
Neuropeptide FF (NPFF) control of magnocellular neurosecretory cells of the rat hypothalamic paraventricular nucleus (PVN). Peptides 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Immunopathogenesis of cerebral malaria. International journal for parasitology 20060501
Effects of COX-1 and COX-2 inhibitors on the firing of rat midbrain dopaminergic neurons--possible involvement of endogenous kynurenic acid. Synapse (New York, N.Y.) 20060401
Spontaneous alternation behaviour in rats: kynurenic acid attenuated deficits induced by MK-801. Behavioural brain research 20060315
Kynurenic acid, an endogenous constituent of rheumatoid arthritis synovial fluid, inhibits proliferation of synoviocytes in vitro. Rheumatology international 20060301
Kynurenate treatment of autaptic hippocampal microcultures affect localized voltage-dependent calcium diffusion in the dendrites. Cell calcium 20060301
Characteristics of neuron activity in the honey bee (Apis mellifera L.) in conditions of kynurenine deficiency. Neuroscience and behavioral physiology 20060301
Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect? Journal of neurochemistry 20060301
Fast vesicle reloading and a large pool sustain high bandwidth transmission at a central synapse. Nature 20060223
Upregulation of the initiating step of the kynurenine pathway in postmortem anterior cingulate cortex from individuals with schizophrenia and bipolar disorder. Brain research 20060216
Putative role of the NTS in alterations in neural control of the circulation following exercise training in rats. American journal of physiology. Regulatory, integrative and comparative physiology 20060201
Projections of the ventrolateral pontine vocalization area in the squirrel monkey. Experimental brain research 20060201
Simultaneous release of glutamate and acetylcholine from single magnocellular 'cholinergic' basal forebrain neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060201
Kynurenic acid attenuates NMDA-induced pial arteriolar dilation in newborn pigs. Brain research 20060119
Characterization of kynurenine aminotransferase III, a novel member of a phylogenetically conserved KAT family. Gene 20060103
Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: Implications for Huntington's disease. Experimental neurology 20060101
Angiotensin II in dorsomedial hypothalamus modulates cardiovascular arousal caused by stress but not feeding in rabbits. American journal of physiology. Regulatory, integrative and comparative physiology 20060101
Tryptophan metabolism and oxidative stress in patients with chronic brain injury. European journal of neurology 20060101
Medial prefrontal cortex NMDA receptors and nitric oxide modulate the parasympathetic component of the baroreflex. The European journal of neuroscience 20060101
Excitatory amino acid receptors in the periaqueductal gray mediate the cardiovascular response evoked by activation of dorsomedial hypothalamic neurons. Neuroscience 20060101
Tricyclic quinoxalinediones, aza-kynurenic acids, and indole-2-carboxylic acids as in vivo active NMDA-glycine antagonists. Current topics in medicinal chemistry 20060101
Gene expression in cortex and hippocampus during acute pneumococcal meningitis. BMC biology 20060101
Kynurenic acid in human saliva--does it influence oral microflora? Pharmacological reports : PR 20060101
Facilitated beam-walking recovery during acute phase by kynurenic acid treatment in a rat model of photochemically induced thrombosis causing focal cerebral ischemia. Neuro-Signals 20060101
Serum kynurenic acid positively correlates with cardiovascular disease risk factor, homocysteine: a study in stroke patients. Pharmacological reports : PR 20060101
Kynurenines, Parkinson's disease and other neurodegenerative disorders: preclinical and clinical studies. Journal of neural transmission. Supplementum 20060101
Human malarial disease: a consequence of inflammatory cytokine release. Malaria journal 20060101
HIV neurotoxicity: potential therapeutic interventions. Journal of biomedicine & biotechnology 20060101
[The influence of kynurenic acid on the content of excitatory and inhibitory mediators in rats with different levels of seizure susceptibility]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20060101
Tryptophan and its metabolites in patients with oral squamous cell carcinoma: preliminary study. Advances in medical sciences 20060101
Excitatory amino acid receptors are involved in morphine-induced synchronous oscillatory discharges in the locus coeruleus of rats. European journal of pharmacology 20051228
Cholinergic systems in the posterior hypothalamic nucleus are involved in blood pressure decrease-induced excitation of anterior hypothalamic area neurons in rats. Neuroscience letters 20051223
Kynurenine metabolism in plasma and in red blood cells in Parkinson's disease. Journal of the neurological sciences 20051215
Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia. Schizophrenia research 20051215
Distinct subunits in heteromeric kainate receptors mediate ionotropic and metabotropic function at hippocampal mossy fiber synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience 20051214
Endogenous neuro-protectants in ammonia toxicity in the central nervous system: facts and hypotheses. Metabolic brain disease 20051201
NMDA receptors mediate feeding elicited by neuropeptide Y in the lateral and perifornical hypothalamus. Brain research 20051123
Ionotropic glutamate receptors in the ventral tegmental area regulate cocaine-seeking behavior in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20051101
Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites. American journal of physiology. Cell physiology 20051101
Role of pressor mechanisms from the NTS and CVLM in control of arterial pressure. American journal of physiology. Regulatory, integrative and comparative physiology 20051101
In situ-produced 7-chlorokynurenate has different effects on evoked responses in rats with limbic epilepsy in comparison to naive controls. Epilepsia 20051101
Changes in synaptic structure underlie the developmental speeding of AMPA receptor-mediated EPSCs. Nature neuroscience 20051001
Cell-specific expression of N-methyl-D-aspartate receptor subunits in Müller glia and neurons from the chick retina. Investigative ophthalmology & visual science 20051001
Long-term intracellular recordings of respiratory neuronal activities in situ during eupnea, gasping and blockade of synaptic transmission. Journal of neuroscience methods 20050930
Regulation of ventral surface chemoreceptors by the central respiratory pattern generator. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050928
Ionotropic glutamate receptors mediate excitatory drive to caudal medullary expiratory neurons in the rabbit. Brain research 20050921
Rapid vesicular release, quantal variability, and spillover contribute to the precision and reliability of transmission at a glomerular synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050907
Activation of noradrenergic locus coeruleus neurons by clozapine and haloperidol: involvement of glutamatergic mechanisms. The international journal of neuropsychopharmacology 20050901
Central nervous mechanisms in the generation of the pattern of breathing. Archives italiennes de biologie 20050901
Kynurenic acid inhibits the release of the neurotrophic fibroblast growth factor (FGF)-1 and enhances proliferation of glia cells, in vitro. Cellular and molecular neurobiology 20050901
Involvement of NMDA receptors in the hypotensive response to the injection of L-glutamate into the lateral hypothalamus of unanesthetized rats. Brain research 20050816
Kynurenine metabolism in multiple sclerosis. Acta neurologica Scandinavica 20050801
Interferon-beta affects the tryptophan metabolism in multiple sclerosis patients. European journal of neurology 20050801
Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in oligodendrocyte cell line (OLN-93). Neurochemical research 20050801
Hypoxic activation of arterial chemoreceptors inhibits sympathetic outflow to brown adipose tissue in rats. The Journal of physiology 20050715
Amino acids modulate the hypotensive effect of angiotensin-(1-7) at the caudal ventrolateral medulla in rats. Regulatory peptides 20050715
Cholinergic stimulation in the lateral septal area activates anterior hypothalamic area neurons via excitatory amino acid receptors in rats. Brain research 20050712
Homocysteine, a risk factor for atherosclerosis, biphasically changes the endothelial production of kynurenic acid. European journal of pharmacology 20050711
Prostaglandin-mediated control of rat brain kynurenic acid synthesis--opposite actions by COX-1 and COX-2 isoforms. Journal of neural transmission (Vienna, Austria : 1996) 20050701
Effect of kynurenine 3-hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in Parkinsonian monkeys. Movement disorders : official journal of the Movement Disorder Society 20050701
Kynurenate and 7-chlorokynurenate formation in chronically epileptic rats. Epilepsia 20050701
Antiallodynic effects of NMDA glycine(B) antagonists in neuropathic pain: possible peripheral mechanisms. Brain research 20050628
Effect of arylformamidase (kynurenine formamidase) gene inactivation in mice on enzymatic activity, kynurenine pathway metabolites and phenotype. Biochimica et biophysica acta 20050620
Glutamate receptors within the nucleus of solitary tract contribute to pancreatic secretion stimulated by intraduodenal hypertonic saline. Autonomic neuroscience : basic & clinical 20050615
Horizontal spread of activity in neocortical inhibitory networks. Brain research. Developmental brain research 20050609
IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity. Molecular psychiatry 20050601
Output-mode transitions are controlled by prolonged inactivation of sodium channels in pyramidal neurons of subiculum. PLoS biology 20050601
Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in cultured cerebral cortical neurons. Journal of neuroscience research 20050601
Cytokine regulation of tryptophan metabolism in the hypothalamic-pituitary-adrenal (HPA) axis: implications for protective and toxic consequences in neuroendocrine regulation. Cellular and molecular neurobiology 20050601
Presynaptic Ca2+ requirements and developmental regulation of posttetanic potentiation at the calyx of Held. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050525
Kynurenine 3-mono-oxygenase inhibitors reduce glutamate concentration in the extracellular spaces of the basal ganglia but not in those of the cortex or hippocampus. Neuropharmacology 20050501
Tryptophan metabolism and oxidative stress in patients with Huntington's disease. Journal of neurochemistry 20050501
Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum. Journal of neurochemistry 20050501
Crystal structures of Aedes aegypti kynurenine aminotransferase. The FEBS journal 20050501
Intercollicular commissural projections modulate neuronal responses in the inferior colliculus. The European journal of neuroscience 20050501
Role of the glycine site of the N-methyl-D-aspartate receptor in synaptic plasticity induced by pairing. The European journal of neuroscience 20050501
D-serine enhances impaired long-term potentiation in CA1 subfield of hippocampal slices from aged senescence-accelerated mouse prone/8. Neuroscience letters 20050429
Systemically administered glucosamine-kynurenic acid, but not pure kynurenic acid, is effective in decreasing the evoked activity in area CA1 of the rat hippocampus. European journal of pharmacology 20050418
Glutamatergic receptors of the rostral ventrolateral medulla are involved in the ventilatory response to hypoxia. Respiratory physiology & neurobiology 20050415
Repeated cocaine administration increases voltage-sensitive calcium currents in response to membrane depolarization in medial prefrontal cortex pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050406
Prolonged nicotine administration results in biphasic, brain-specific changes in kynurenate levels in the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050401
Activation of slowly conducting medullary raphe-spinal neurons, including serotonergic neurons, increases cutaneous sympathetic vasomotor discharge in rabbit. American journal of physiology. Regulatory, integrative and comparative physiology 20050401
Glycine-induced neurotoxicity in organotypic hippocampal slice cultures. Experimental brain research 20050301
Glutamate neurotransmission is not required for, but may modulate, hypoxic sensitivity of pre-Bötzinger complex in vivo. Journal of neurophysiology 20050301
Schwann cells exhibit excitotoxicity consistent with release of NMDA receptor agonists. Journal of neuroscience research 20050301
Overproduction and preliminary crystallographic study of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3. Acta crystallographica. Section F, Structural biology and crystallization communications 20050301
Glutamate and GABA(B) transmissions in lateral amygdala are involved in startle-like electromyographic (EMG) potentiation caused by activation of auditory thalamus. Neuroscience letters 20050210
GABAergic neurons in the central region of the spinal cord: a novel substrate for sympathetic inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050202
Age-dependent biphasic changes in ischemic sensitivity in the striatum of Huntington's disease R6/2 transgenic mice. Journal of neurophysiology 20050201
Role of paraventricular nucleus in the cardiogenic sympathetic reflex in rats. American journal of physiology. Regulatory, integrative and comparative physiology 20050201
Structural consequences of D481N/K483Q mutation at glycine binding site of NMDA ionotropic glutamate receptors: a molecular dynamics study. Journal of biomolecular structure & dynamics 20050201
Dual effect of DL-homocysteine and S-adenosylhomocysteine on brain synthesis of the glutamate receptor antagonist, kynurenic acid. Journal of neuroscience research 20050201
Metabotropic glutamate receptors inhibit mechanosensitivity in vagal sensory neurons. Gastroenterology 20050201
Autogenic modulation of mechanoreceptor excitability by glutamate release from synaptic-like vesicles: evidence from the rat muscle spindle primary sensory ending. The Journal of physiology 20050115
Antagonism of glutamate receptors in the intermediate and caudal NTS of awake rats produced no changes in the hypertensive response to chemoreflex activation. Autonomic neuroscience : basic & clinical 20050115
Respiratory responses evoked by blockades of ionotropic glutamate receptors within the Bötzinger complex and the pre-Bötzinger complex of the rabbit. The European journal of neuroscience 20050101
5-Hydroxytryptamine action in the rat olfactory bulb: in vitro electrophysiological patch-clamp recordings of juxtaglomerular and mitral cells. Neuroscience 20050101
Substance P-driven feed-forward inhibitory activity in the mammalian spinal cord. Molecular pain 20050101
Quinolinic acid selectively induces apoptosis of human astrocytes: potential role in AIDS dementia complex. Journal of neuroinflammation 20050101
Echolocation calls and communication calls are controlled differentially in the brainstem of the bat Phyllostomus discolor. BMC biology 20050101
Metabonomics with 1H-NMR spectroscopy and liquid chromatography-mass spectrometry applied to the investigation of metabolic changes caused by gentamicin-induced nephrotoxicity in the rat. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20050101
Age-related increase of kynurenic acid in human cerebrospinal fluid - IgG and beta2-microglobulin changes. Neuro-Signals 20050101
The photopic ERG of the albino guinea pig (Cavia porcellus): a model of the human photopic ERG. Documenta ophthalmologica. Advances in ophthalmology 20050101
Suprathreshold excitation of network of frog tectal neurons by discharging of single retina moving-edge detector. Medicina (Kaunas, Lithuania) 20050101
Effect of pesticides on kynurenic acid production in rat brain slices. Annals of agricultural and environmental medicine : AAEM 20050101
Dose-independent antinociceptive interaction of endogenous ligands at the spinal level. Brain research 20041210
Suprathreshold excitation of frog tectal neurons by short spike trains of single retinal ganglion cell. Experimental brain research 20041201
Contribution to sympathetic vasomotor tone of tonic glutamatergic inputs to neurons in the RVLM. American journal of physiology. Regulatory, integrative and comparative physiology 20041201
Acute and chronic increases in osmolality increase excitatory amino acid drive of the rostral ventrolateral medulla in rats. American journal of physiology. Regulatory, integrative and comparative physiology 20041201
Neostriatal and cortical quinolinate levels are increased in early grade Huntington's disease. Neurobiology of disease 20041201
Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus. Neurobiology of disease 20041201
pH dependence, substrate specificity and inhibition of human kynurenine aminotransferase I. European journal of biochemistry 20041201
Pharmacological manipulation of brain kynurenine metabolism. Annals of the New York Academy of Sciences 20041201
Crystal structure of human kynurenine aminotransferase I. The Journal of biological chemistry 20041126
Cysteine and keto acids modulate mosquito kynurenine aminotransferase catalyzed kynurenic acid production. FEBS letters 20041119
Nucleus isthmi and control of breathing in amphibians. Respiratory physiology & neurobiology 20041115
Modulation of reflex and sleep related apnea by pedunculopontine tegmental and intertrigeminal neurons. Respiratory physiology & neurobiology 20041115
Cardiovascular responses to microinjection of ATP into the nucleus tractus solitarii of awake rats. American journal of physiology. Regulatory, integrative and comparative physiology 20041101
Kynurenine administered together with probenecid markedly inhibits pentylenetetrazol-induced seizures. An electrophysiological and behavioural study. Neuropharmacology 20041101
Putative NMDA receptors in Hydra: a biochemical and functional study. The European journal of neuroscience 20041101
Sodium-activated potassium conductance participates in the depolarizing afterpotential following a single action potential in rat hippocampal CA1 pyramidal cells. Brain research 20041015
Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules. Bioorganic & medicinal chemistry 20041015
Voltammetric study of the control of striatal dopamine release by glutamate. Journal of neurochemistry 20041001
Glutamatergic neurotransmission modulates hypoxia-induced hyperventilation but not anapyrexia. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20041001
Unilateral cochlear ablation produces greater loss of inhibition in the contralateral inferior colliculus. The European journal of neuroscience 20041001
Tracheal tone and the role of ionotropic glutamate receptors in the nucleus ambiguus. Brain research 20040917
Carbamazepine enhances brain production of kynurenic acid in vitro. European journal of pharmacology 20040913
Cholinergic and glutamatergic spontaneous and evoked excitatory postsynaptic currents in optic lobe neurons of cuttlefish, Sepia officinalis. Brain research 20040910
Endogenous kynurenic acid disrupts prepulse inhibition. Biological psychiatry 20040815
Afferent synaptic transmission in a hair cell organ: pharmacological and physiological analysis of the role of the extended refractory period. Journal of neurophysiology 20040801
Neuronal A1 receptors mediate increase in extracellular kynurenic acid after local intrastriatal adenosine infusion. Journal of neurochemistry 20040801
Presynaptic activity and Ca2+ entry are required for the maintenance of NMDA receptor-independent LTP at visual cortical excitatory synapses. Journal of neurophysiology 20040801
Glutamatergic-receptors blockade does not regularize the slow wave sleep bursty pattern of subthalamic neurons. The European journal of neuroscience 20040701
Differential presynaptic modulation of excitatory and inhibitory autaptic currents in cultured hippocampal neurons. Brain research 20040625
The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants. Neurochemistry international 20040601
A metabonomic investigation of the biochemical effects of mercuric chloride in the rat using 1H NMR and HPLC-TOF/MS: time dependent changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity. The Analyst 20040601
Phasic bursts in rat magnocellular neurosecretory cells are not intrinsically regenerative in vivo. The European journal of neuroscience 20040601
Effects of angiotensin II type 1 receptor antagonist on pressor responses to pulsatile compression of the rostral ventrolateral medulla in rats. Hypertension research : official journal of the Japanese Society of Hypertension 20040601
Cyclosporin A-induced changes in endogenous metabolites in rat urine: a metabonomic investigation using high field 1H NMR spectroscopy, HPLC-TOF/MS and chemometrics. Journal of pharmaceutical and biomedical analysis 20040528
Memantine inhibits and reverses the Alzheimer type abnormal hyperphosphorylation of tau and associated neurodegeneration. FEBS letters 20040521
Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040512
Ionotropic excitatory amino acid receptors in pre-Botzinger complex play a modulatory role in hypoxia-induced gasping in vivo. Journal of applied physiology (Bethesda, Md. : 1985) 20040501
Excitatory amino acids in rostral ventrolateral medulla support blood pressure during water deprivation in rats. American journal of physiology. Heart and circulatory physiology 20040501
ANG II-induced excitation of paraventricular nucleus magnocellular neurons: a role for glutamate interneurons. American journal of physiology. Regulatory, integrative and comparative physiology 20040501
Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro. Neuropharmacology 20040501
Clozapine modulates midbrain dopamine neuron firing via interaction with the NMDA receptor complex. Synapse (New York, N.Y.) 20040501
Kynurenine aminotransferase in the supratentorial dura mater of the rat: effect of stimulation of the trigeminal ganglion. Experimental neurology 20040401
Distinct mechanisms of bidirectional activity-dependent synaptic plasticity in superficial and deep layers of rat entorhinal cortex. The European journal of neuroscience 20040401
Cortical spreading depression augments kynurenate levels and reduces malonate toxicity in the rat cortex. Brain research 20040326
Parabrachial neurons mediate dorsal periaqueductal gray evoked respiratory responses in the rat. Journal of applied physiology (Bethesda, Md. : 1985) 20040301
Age-dependent decrease of retinal kynurenate and kynurenine aminotransferases in DBA/2J mice, a model of ocular hypertension. Vision research 20040301
Kynurenic acid in ALS patients. Acta neurologica Scandinavica 20040301
Kynurenic acid production in cultured bovine aortic endothelial cells. Homocysteine is a potent inhibitor. Naunyn-Schmiedeberg's archives of pharmacology 20040301
Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands. Journal of structural biology 20040301
Glutamate release increases during mossy-CA3 LTP but not during Schaffer-CA1 LTP. The European journal of neuroscience 20040301
Selective antagonism of rat inhibitory glycine receptor subunits. The Journal of physiology 20040201
Kynurenic acid synthesis in cerebral cortical slices of rats with progressing symptoms of thioacetamide-induced hepatic encephalopathy. Journal of neuroscience research 20040201
Role of L-glutamate in the locus coeruleus of rats in hypoxia-induced hyperventilation and anapyrexia. Respiratory physiology & neurobiology 20040115
Comparative study on the effects of kynurenic acid and glucosamine-kynurenic acid. Pharmacology, biochemistry, and behavior 20040101
Content of kynurenic acid and activity of kynurenine aminotransferases in mammalian eyes. Ophthalmic research 20040101
Subthreshold contribution of N-methyl-d-aspartate receptors to long-term potentiation induced by low-frequency pairing in rat hippocampal CA1 pyramidal cells. Neuroscience 20040101
Kynurenate in the pontine reticular formation inhibits acoustic and trigeminal nucleus-evoked startle, but not vestibular nucleus-evoked startle. Neuroscience 20040101
Decreased expression of kynurenine aminotransferase-I (KAT-I) in the substantia nigra of mice after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment. Neuroscience 20040101
Basic science behind the catastrophic epilepsies. Epilepsia 20040101
Spontaneous activity of rat pretectal nuclear complex neurons in vitro. BMC neuroscience 20040101
Role of glutamate receptors in nucleus accumbens core and shell in spatial behaviour of rats. Neuroscience 20040101
High-probability uniquantal transmission at excitatory synapses in barrel cortex. Science (New York, N.Y.) 20031212
The commissure of the inferior colliculus shapes frequency response areas in rat: an in vivo study using reversible blockade with microinjection of kynurenic acid. Experimental brain research 20031201
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). Naunyn-Schmiedeberg's archives of pharmacology 20031201
Effect of excess extracellular glutamate on dendrite growth from cerebral cortical neurons at 3 days in vitro: Involvement of NMDA receptors. Journal of neuroscience research 20031201
Active release of glycine or D-serine saturates the glycine site of NMDA receptors at the cerebellar mossy fibre to granule cell synapse. The European journal of neuroscience 20031201
Partial hippocampal kindling increases GABAB receptor-mediated postsynaptic currents in CA1 pyramidal cells. Epilepsy research 20031101
Determination of alpha-aminoadipic acid in brain, peripheral tissues, and body fluids using GC/MS with negative chemical ionization. Brain research. Molecular brain research 20031021
Identification of central mechanisms vital for breathing in the channel catfish, Ictalurus punctatus. Respiratory physiology & neurobiology 20031016
Unmyelinated axons in the rat hippocampus hyperpolarize and activate an H current when spike frequency exceeds 1 Hz. The Journal of physiology 20031015
Potentiation of N-methyl-D-aspartate-induced currents by the nootropic drug nefiracetam in rat cortical neurons. The Journal of pharmacology and experimental therapeutics 20031001
Inhibitory action of clozapine on rat ventral tegmental area dopamine neurons following increased levels of endogenous kynurenic acid. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031001
Sympathoexcitation by PVN-injected bicuculline requires activation of excitatory amino acid receptors. Hypertension (Dallas, Tex. : 1979) 20031001
Role of endogenous angiotensin II on glutamatergic actions in the rostral ventrolateral medulla in Goldblatt hypertensive rats. Hypertension (Dallas, Tex. : 1979) 20031001
Glutamatergic input in the PVN is important in renal nerve response to elevations in osmolality. American journal of physiology. Renal physiology 20031001
The kynurenine 3-hydroxylase inhibitor Ro 61-8048 improves dystonia in a genetic model of paroxysmal dyskinesia. European journal of pharmacology 20030930
Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria. The Journal of infectious diseases 20030915
Muscarinic acetylcholine receptors potentiate the GABAergic transmission in the developing rat inferior colliculus. Neuropharmacology 20030901
Effect of systemic administration of L-kynurenine on corticocerebral blood flow under normal and ischemic conditions of the brain in conscious rabbits. Journal of cardiovascular pharmacology 20030901
Evidence for a glutamatergic modulation of the cholinergic function in the human enteric nervous system via NMDA receptors. European journal of pharmacology 20030822
Substance P Acts through local circuits within the rat dorsal raphe nucleus to alter serotonergic neuronal activity. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030806
Micromolar brain levels of kynurenic acid are associated with a disruption of auditory sensory gating in the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030801
L-cysteine sulphinate, endogenous sulphur-containing amino acid, inhibits rat brain kynurenic acid production via selective interference with kynurenine aminotransferase II. Neuroscience letters 20030731
Tryptophan metabolites and brain disorders. Clinical chemistry and laboratory medicine 20030701
Behavioral effects of NMDA receptor agonists and antagonists in combination with nitric oxide-related compounds. European journal of pharmacology 20030620
Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core. The EMBO journal 20030616
Distinguishing between presynaptic and postsynaptic mechanisms of short-term depression during action potential trains. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615
Intertrigeminal region attenuates reflex apnea and stabilizes respiratory pattern in rats. Brain research 20030613
Involvement of N-methyl-D-aspartate receptors in post-hypoxic depression of the dorsomedial medulla in cats. Neuroscience letters 20030612
Optical detection of developmental origin of synaptic function in the embryonic chick vestibulocochlear nuclei. Journal of neurophysiology 20030601
Brainstem mechanisms of hypertension: role of the rostral ventrolateral medulla. Current hypertension reports 20030601
Endogenous protectant kynurenic acid in amyotrophic lateral sclerosis. Acta neurologica Scandinavica 20030601
Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site. Journal of neurovirology 20030601
Ontogenic changes of kynurenine aminotransferase I activity and its expression in the chicken retina. Vision research 20030601
Role of paraventricular nucleus in regulation of sympathetic nerve frequency components. American journal of physiology. Heart and circulatory physiology 20030501
Seizure-like activity leads to the release of BAD from 14-3-3 protein and cell death in hippocampal neurons in vitro. Cell death and differentiation 20030501
Developmental increase in vesicular glutamate content does not cause saturation of AMPA receptors at the calyx of Held synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030501
Chronic treatment with ionotropic glutamate receptor antagonist kynurenate affects GABAergic synaptic transmission in rat hippocampal cell cultures. Neuroscience letters 20030424
Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists. Bioorganic & medicinal chemistry 20030417
D-Serine differently modulates NMDA receptor function in rat CA1 hippocampal pyramidal cells and interneurons. The Journal of physiology 20030415
Role of glutamate in the nucleus isthmi on the hypoxia- and hypercarbia-induced hyperventilation of toads. Respiratory physiology & neurobiology 20030415
Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport. The Journal of biological chemistry 20030411
Mechanism of the distance-dependent scaling of Schaffer collateral synapses in rat CA1 pyramidal neurons. The Journal of physiology 20030401
Ameliorative effects of histamine on 7-chlorokynurenic acid-induced spatial memory deficits in rats. Psychopharmacology 20030401
Sympathoinhibitory pathway from caudal midline medulla to RVLM is independent of baroreceptor reflex pathway. American journal of physiology. Regulatory, integrative and comparative physiology 20030401
Carbachol-induced network oscillations in the intact cerebral cortex of the newborn rat. Cerebral cortex (New York, N.Y. : 1991) 20030401
GABAC receptors in the rat superior colliculus and pretectum participate in synaptic neurotransmission. Journal of neurophysiology 20030401
Kynurenic acid enhances electroacupuncture analgesia in normal and carrageenan-injected rats. Brain research 20030321
Retraction. Kynurenate attenuates the accumulation of diacylglycerol and free fatty acids after experimental brain injury in the rat. [Brain Research 832 (1999) 7-12]. Brain research 20030307
Alterations of kynurenic acid content in the retina in response to retinal ganglion cell damage. Vision research 20030301
Spontaneous synaptic activity in an organotypic culture of the mouse retina. Investigative ophthalmology & visual science 20030301
Medullary and supramedullary mechanisms regulating sympathetic vasomotor tone. Acta physiologica Scandinavica 20030301
Glutamate receptors in RVLM modulate sympathetic baroreflex in conscious rabbits. American journal of physiology. Regulatory, integrative and comparative physiology 20030201
Activation of peripheral excitatory amino acid receptors decreases the duration of local anesthesia. Anesthesiology 20030201
Pedunculopontine tegmental stimulation evokes striatal dopamine efflux by activation of acetylcholine and glutamate receptors in the midbrain and pons of the rat. The European journal of neuroscience 20030201
Involvement of glutamate in gastrointestinal vago-vagal reflexes initiated by gastrointestinal distention in the rat. Autonomic neuroscience : basic & clinical 20030131
Kynurenines and the respiratory parameters on rat heart mitochondria. Life sciences 20030124
Role of L-glutamate in systemic AVP-induced hypothermia. Journal of applied physiology (Bethesda, Md. : 1985) 20030101
Differential alterations in the expression of NMDA receptor subunits following chronic ethanol treatment in primary cultures of rat cortical and hippocampal neurones. Neurochemistry international 20030101
alpha-[11C]-Methyl-L-tryptophan PET identifies the epileptogenic tuber and correlates with interictal spike frequency. Epilepsy research 20030101
Kynurenate production by cultured human astrocytes. Journal of neural transmission (Vienna, Austria : 1996) 20030101
Maintenance of sympathetic tone by a nickel chloride-sensitive mechanism in the rostral ventrolateral medulla of the adult rat. Neuroscience 20030101
Role of ventrolateral periaqueductal gray neurons in the behavioral and cardiovascular responses to contextual conditioned fear and poststress recovery. Neuroscience 20030101
FK506 attenuates 1-methyl-4-phenylpyridinium- and 3-nitropropionic acid-evoked inhibition of kynurenic acid synthesis in rat cortical slices. Acta neurobiologiae experimentalis 20030101
Blockade of NMDA receptor subtype NR2B prevents seizures but not apoptosis of dentate gyrus neurons in bacterial meningitis in infant rats. BMC neuroscience 20030101
Comparative inhibition by substrate analogues 3-methoxy- and 3-hydroxydesaminokynurenine and an improved 3 step purification of recombinant human kynureninase. BMC biochemistry 20030101
Endogenous level of kynurenic acid and activities of kynurenine aminotransferases following transient global ischemia in the gerbil hippocampus. Polish journal of pharmacology 20030101
Cytokine-serotonin interaction through IDO: a neurodegeneration hypothesis of depression. Medical hypotheses 20030101
Excitatory amino acid receptor activation in the raphe pallidus area mediates prostaglandin-evoked thermogenesis. Neuroscience 20030101
Kynurenic acid prevented social recognition deficits induced by MK-801 in rats. Physiological research 20030101
Deficit of endogenous kynurenic acid in the frontal cortex of rats with a genetic form of absence epilepsy. Polish journal of pharmacology 20030101
Diclofenac increases the accumulation of kynurenate following tryptophan pretreatment in the rat: a possible factor contributing to its antihyperalgesic effect. Inflammopharmacology 20030101
3-Hydroxykynurenine and quinolinate: pathogenic synergism in early grade Huntington's disease? Advances in experimental medicine and biology 20030101
Kynurenic acid and schizophrenia. Advances in experimental medicine and biology 20030101
Quinolinic acid in the pathogenesis of Alzheimer's disease. Advances in experimental medicine and biology 20030101
Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment. Advances in experimental medicine and biology 20030101
Levels of purine, kynurenine and lipid peroxidation products in patients with inflammatory bowel disease. Advances in experimental medicine and biology 20030101
Increase in conversion of tryptophan to niacin in pregnant rats. Advances in experimental medicine and biology 20030101
The enol tautomer of indole-3-pyruvic acid as a biological switch in stress responses. Advances in experimental medicine and biology 20030101
Modulation of the kynurine pathway of tryptophan metabolism in search for neuroprotective agents. Focus on kynurenine-3-hydroxylase. Advances in experimental medicine and biology 20030101
The effects of phthalate esters on the tryptophan-niacin metabolism. Advances in experimental medicine and biology 20030101
Photochemical properties of kynurenine pathway metabolites and indoleamines. Advances in experimental medicine and biology 20030101
Drosophila mutants of the kynurenine pathway as a model for ageing studies. Advances in experimental medicine and biology 20030101
Cellular mechanisms of orexin actions on paraventricular nucleus neurones in rat hypothalamus. The Journal of physiology 20021215
GABA-mediated neurotransmission in the ventrolateral NTS plays a role in respiratory regulation in the rat. American journal of physiology. Regulatory, integrative and comparative physiology 20021201
Unconventional ligands and modulators of nicotinic receptors. Journal of neurobiology 20021201
Long-lasting modulation of synaptic input to Purkinje neurons by Bergmann glia stimulation in rat brain slices. The Journal of physiology 20021201
Masking synchronous GABA-mediated potentials controls limbic seizures. Epilepsia 20021201
Thalamocortical oscillations in a genetic model of absence seizures. The European journal of neuroscience 20021201
Quantitation of tryptophan, kynurenine and kynurenic acid in human plasma by capillary liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021125
Formation of kynurenic and xanthurenic acids from kynurenine and 3-hydroxykynurenine in the dinoflagellate Lingulodinium polyedrum: role of a novel, oxidative pathway. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20021101
c-Fos expression in the midbrain periaqueductal gray after chemoreceptor and baroreceptor activation. American journal of physiology. Heart and circulatory physiology 20021101
GABAergic and glutamatergic afferents in the dorsal raphe nucleus mediate morphine-induced increases in serotonin efflux in the rat central nervous system. The Journal of pharmacology and experimental therapeutics 20021101
Nicotinic receptors regulate the release of glycine onto lamina X neurones of the rat spinal cord. Neuropharmacology 20021101
The rat ponto-medullary network responsible for paradoxical sleep onset and maintenance: a combined microinjection and functional neuroanatomical study. The European journal of neuroscience 20021101
Neuropeptides, amines and amino acids as mediators of the sympathetic effects of paraventricular nucleus activation in the rat. Experimental physiology 20021101
Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism. Brain research 20021011
The involvement of glia in long-term plasticity in the spinal dorsal horn of the rat. Neuroreport 20021007
Decreased level of kynurenic acid in cerebrospinal fluid of relapsing-onset multiple sclerosis patients. Neuroscience letters 20021004
Mechanisms mediating regional sympathoactivatory responses to stimulation of NTS A(1) adenosine receptors. American journal of physiology. Heart and circulatory physiology 20021001
Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities. The Journal of pharmacology and experimental therapeutics 20021001
Ventrolateral medulla AT1 receptors support blood pressure in hypertensive rats. Hypertension (Dallas, Tex. : 1979) 20021001
Stimulation of cortical acetylcholine release following blockade of ionotropic glutamate receptors in nucleus accumbens. The European journal of neuroscience 20021001
Excitatory amino acid receptor blockade within the caudal pressor area and rostral ventrolateral medulla alters cardiovascular responses to nucleus raphe obscurus stimulation in rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20021001
tGLP-1 action on the isolated hypothalamo-neurohypophysial system under glutamate receptor blockade. Brain research bulletin 20020930
A missense mutation in kynurenine aminotransferase-1 in spontaneously hypertensive rats. The Journal of biological chemistry 20020927
[Analgesic effect of kynurenic acid]. Ideggyogyaszati szemle 20020920
A glycine receptor antagonist, strychnine, blocked NMDA receptor activation in the neonatal mouse neocortex. Neuroreport 20020916
1-Methyl-4-phenylpyridinium and 3-nitropropionic acid diminish cortical synthesis of kynurenic acid via interference with kynurenine aminotransferases in rats. Neuroscience letters 20020913
Neural mechanisms involved in the functional linking of motor cortical points. Experimental brain research 20020901
Antinociceptive effect of cardiopulmonary chemoreceptor and baroreceptor reflex activation in the rat. Pain 20020901
Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures. Journal of neurochemistry 20020901
Complex effects of CNQX on CA1 interneurons of the developing rat hippocampus. Neuropharmacology 20020901
Effect of 3-nitropropionic acid on kynurenine aminotransferase in the rat brain. Experimental neurology 20020901
Evidence for tonic disinhibition of RVLM sympathoexcitatory neurons from the caudal pressor area. Autonomic neuroscience : basic & clinical 20020830
Tonic sympathoinhibition arising from the hypothalamic PVN in the conscious rabbit. Brain research 20020823
Isolation, characterization, and functional expression of kynurenine aminotransferase cDNA from the yellow fever mosquito, Aedes aegypti(1). Insect biochemistry and molecular biology 20020801
Contributions from rostral medullary nuclei to coordination of swallowing and breathing in awake goats. Journal of applied physiology (Bethesda, Md. : 1985) 20020801
Spillover of glutamate onto synaptic AMPA receptors enhances fast transmission at a cerebellar synapse. Neuron 20020801
Changes of kynurenic acid content in the rat and chicken retina during ontogeny. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20020801
Endogenous kynurenines as targets for drug discovery and development. Nature reviews. Drug discovery 20020801
[The role of dorsomedial hypothalamic nucleus in the cardiovascular responses induced by habenular nucleus stimulation and inhibitory effect of deep peroneal nerve]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20020801
In vitro and in vivo antagonistic activities of SM-31900 for the NMDA receptor glycine-binding site. Brain research 20020719
Endothelium-dependent production and liberation of kynurenic acid by rat aortic rings exposed to L-kynurenine. European journal of pharmacology 20020719
'Untypical aging off-flavor' in wine: synthesis of potential degradation compounds of indole-3-acetic acid and kynurenine and their evaluation as precursors of 2-aminoacetophenone. Journal of agricultural and food chemistry 20020717
The pharmacological manipulation of glutamate receptors and neuroprotection. European journal of pharmacology 20020705
Glutamate mediates an excitatory influence of the paraventricular hypothalamic nucleus on the dorsal motor nucleus of the vagus. Journal of neurophysiology 20020701
Involvement of nitric oxide production via kynurenic acid-sensitive glutamate receptors in DOPA-induced depressor responses in the nucleus tractus solitarii of anesthetized rats. Neuroscience research 20020701
[Microanalysis of tryptophan metabolites and suppressor factor of delayed-type hypersensitivity in mice]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020701
Growth-promoting activity of pyrazinoic acid, a putative active compound of antituberculosis drug pyrazinamide, in niacin-deficient rats through the inhibition of ACMSD activity. Bioscience, biotechnology, and biochemistry 20020701
Ionotropic glutamate receptors in the rostral ventrolateral medulla mediate sympathetic responses to acute stress in conscious rabbits. Autonomic neuroscience : basic & clinical 20020628
Activation of ventral tegmental area cells by the bed nucleus of the stria terminalis: a novel excitatory amino acid input to midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615
Caudal ventrolateral medulla mediates the depressor response elicited by the greater splanchnic nerve afferent stimulation in rats. Neuroscience letters 20020607
The antinociceptive effect of intrathecal kynurenic acid and its interaction with endomorphin-1 in rats. European journal of pharmacology 20020607
Effects of pedunculopontine nucleus (PPN) stimulation on caudal pontine reticular formation (PnC) neurons in vitro. Journal of neurophysiology 20020601
Regulation of kynurenic acid synthesis in C6 glioma cells. Journal of neuroscience research 20020601
Effects of excitatory amino acid antagonists on the activity of inferior colliculus neurons during sleep and wakefulness. Hearing research 20020601
Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats. Bioscience, biotechnology, and biochemistry 20020601
Synthesis and in vitro pharmacology of substituted quinoline-2,4-dicarboxylic acids as inhibitors of vesicular glutamate transport. Journal of medicinal chemistry 20020523
Vasodilatory N-methyl-D-aspartate receptors are constitutively expressed in rat kidney. Journal of the American Society of Nephrology : JASN 20020501
A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020501
Increased phasic activity of dopaminergic neurones in the rat ventral tegmental area following pharmacologically elevated levels of endogenous kynurenic acid. Acta physiologica Scandinavica 20020501
The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory. Neuron 20020425
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Spontaneous retinal activity is tonic and does not drive tectal activity during activity-dependent refinement in regeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020401
Evidence against the presence of NMDA receptors at a central glutamatergic synapse in leeches. Invertebrate neuroscience : IN 20020401
Excitatory and inhibitory responses of dopamine neurons in the ventral tegmental area to nicotine. Synapse (New York, N.Y.) 20020315
The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria. The Journal of infectious diseases 20020301
Tryptophan metabolism via the kynurenine pathway in experimental chronic renal failure. Nephron 20020301
Effect of agmatine on locus coeruleus neuron activity: possible involvement of nitric oxide. British journal of pharmacology 20020301
Effect of systemic L-DOPA administration on extracellular kynurenate levels in the rat striatum. Journal of neural transmission (Vienna, Austria : 1996) 20020301
Synergistic versus antagonistic actions of glutamate and glutathione: the role of excitotoxicity and oxidative stress in neuronal disease. Cellular and molecular biology (Noisy-le-Grand, France) 20020301
Design, synthesis and activity of ascorbic acid prodrugs of nipecotic, kynurenic and diclophenamic acids, liable to increase neurotropic activity. Journal of medicinal chemistry 20020131
Evidence for a tonic GABA-ergic inhibition of excitatory respiratory-related afferents to presympathetic neurons in the rostral ventrolateral medulla. Brain research 20020104
Synaptically evoked membrane potential oscillations induced by substance P in lamprey motor neurons. Journal of neurophysiology 20020101
Synchronized spikes of thalamocortical axonal terminals and cortical neurons are detectable outside the pig brain with MEG. Journal of neurophysiology 20020101
Kynureninase is a novel candidate gene for hypertension in spontaneously hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension 20020101
[Polar constituents of the ascidia Botryllus schlosseri]. Bioorganicheskaia khimiia 20020101
Role of excitatory amino acid inputs to the rostral ventrolateral medulla in cardiovascular regulation. Clinical and experimental pharmacology & physiology 20020101
Purine, kynurenine, neopterin and lipid peroxidation levels in inflammatory bowel disease. Journal of biomedical science 20020101
Dynamic diversity of the tryptophan pathway in chlamydiae: reductive evolution and a novel operon for tryptophan recapture. Genome biology 20020101
[Effect of kynurenic acid on catecholamine content in the brain of rats with different susceptibility to seizures]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20020101
Kynurenine aminotransferase and glutamine transaminase K of Escherichia coli: identity with aspartate aminotransferase. The Biochemical journal 20011215
Serotonin (1A) receptor ligands act on norepinephrine neuron firing through excitatory amino acid and GABA(A) receptors: a microiontophoretic study in the rat locus coeruleus. Synapse (New York, N.Y.) 20011215
Presence of kynurenic acid and kynurenine aminotransferases in the inner retina. Neuroreport 20011204
Kynurenine and its metabolites in the rat with experimental renal insufficiency. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20011201
Depressor and bradycardic actions of L-proline injected into the nucleus tractus solitarii of anesthetized rats. The Japanese journal of physiology 20011201
[Influence of premature rupture of fetal membranes on kynurenic acid concentration in umbilical cord blood]. Ginekologia polska 20011201
Ethanol inhibition of N-methyl-D-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue. The Journal of biological chemistry 20011130
Glycine receptor-mediated inhibition of dopamine and non-dopamine neurons of the rat ventral tegmental area in vitro. Brain research 20011123
Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia. Neuroscience letters 20011102
CNQX increases GABA-mediated synaptic transmission in the cerebellum by an AMPA/kainate receptor-independent mechanism. Neuropharmacology 20011101
Evidence for alpha-2 adrenoreceptor modulation of arterial chemoreflexes in the caudal solitary nucleus of the rat. American journal of physiology. Regulatory, integrative and comparative physiology 20011101
Neurotransmitters in the thalamus relaying visceral input to the insular cortex in the rat. American journal of physiology. Regulatory, integrative and comparative physiology 20011101
Physiological characteristics of the projection pathway from the medial preoptic to the nucleus raphe magnus of the rat and its modulation by the periaqueductal gray. Pain 20011101
Thyrotropin-releasing hormone: role in the treatment of West syndrome and related epileptic encephalopathies. Brain & development 20011101
Role of spinal NMDA receptors, protein kinase C and nitric oxide synthase in the hyperalgesia induced by magnesium deficiency in rats. British journal of pharmacology 20011101
Multivesicular release at climbing fiber-Purkinje cell synapses. Neuron 20011025
Estimation of quantal size and number of functional active zones at the calyx of Held synapse by nonstationary EPSC variance analysis. The Journal of neuroscience : the official journal of the Society for Neuroscience 20011015
L-type Ca2+ channel-mediated short-term plasticity of GABAergic synapses. Nature neuroscience 20011001
The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications. The Journal of neuroscience : the official journal of the Society for Neuroscience 20011001
Increased cortical kynurenate content in schizophrenia. Biological psychiatry 20011001
Characterization of the spontaneous synaptic activity of amacrine cells in the mouse retina. Journal of neurophysiology 20011001
Overexpression of eNOS in the RVLM causes hypotension and bradycardia via GABA release. Hypertension (Dallas, Tex. : 1979) 20011001
Kynurenine production and catabolism in fetal sheep with embolized or nonembolized placentas. American journal of obstetrics and gynecology 20011001
Stimulation of 5-HT(1A) receptors in the dorsal raphe ameliorates the impairment of spatial learning caused by intrahippocampal 7-chloro-kynurenic acid in naive and pretrained rats. Psychopharmacology 20011001
Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats. Bioscience, biotechnology, and biochemistry 20011001
Developmental inhibitory gate controls the relay of activity to the superficial layers of the visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010901
Potentiation of NMDA receptor function through somatostatin release: a possible mechanism for the cognition-enhancing activity of GABA(B) receptor antagonists. Neuropharmacology 20010901
The role of glycineB binding site and glycine transporter (GlyT1) in the regulation of [3H]GABA and [3H]glycine release in the rat brain. Neurochemical research 20010901
Pressor response to unilateral carotid chemoreceptor activation is not affected by ipsilateral antagonism of excitatory amino acid receptors in the rostral ventrolateral medulla of awake rats. Autonomic neuroscience : basic & clinical 20010813
Increased kynurenic acid in the brain after neonatal asphyxia. Life sciences 20010803
Effect of xanthurenic acid on infectivity of Plasmodium falciparum to Anopheles stephensi. International journal for parasitology 20010801
Multiple rostral medullary nuclei can influence breathing in awake goats. Journal of applied physiology (Bethesda, Md. : 1985) 20010801
Neonatal asphyxia in rats: acute effects on cerebral kynurenine metabolism. Pediatric research 20010801
Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection. Journal of neurochemistry 20010801
Xanthurenic acid inhibits metal ion-induced lipid peroxidation and protects NADP-isocitrate dehydrogenase from oxidative inactivation. Journal of nutritional science and vitaminology 20010801
The role of glutamate and vasopressin in the excitation of RVL neurones by paraventricular neurones. Brain research 20010720
Developmental changes in 5-hydroxytryptamine-induced rhythmic activity in the spinal cord of rat fetuses in vitro. Neuroscience letters 20010706
Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant form of amyloid precursor protein. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010701
Reversible inactivation of the dorsal nucleus of the lateral lemniscus reveals its role in the processing of multiple sound sources in the inferior colliculus of bats. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010701
Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010701
Synaptic drive to motoneurons during fictive swimming in the developing zebrafish. Journal of neurophysiology 20010701
Intraspinal amino acid neurotransmitter activities are involved in the generation of rhythmic sympathetic nerve discharge in newborn rat spinal cord. Brain research 20010615
Kynurenines in the CNS: from endogenous obscurity to therapeutic importance. Progress in neurobiology 20010601
Time-dependent reversal of long-term potentiation by low-frequency stimulation at the hippocampal mossy fiber-CA3 synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601
Local opiate withdrawal in locus coeruleus neurons in vitro. Journal of neurophysiology 20010601
Presynaptic kynurenate-sensitive receptors inhibit glutamate release. The European journal of neuroscience 20010601
Neurotransmission of the cardiovascular reflexes in the nucleus tractus solitarii of awake rats. Annals of the New York Academy of Sciences 20010601
Excitatory inputs to the RVLM in the context of the baroreceptor reflex. Annals of the New York Academy of Sciences 20010601
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats. Bioscience, biotechnology, and biochemistry 20010601
[Effect of feeding with a poisonous mushroom Clitocybe acromelalga on the metabolism of tryptophan-niacin in rats]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010601
Excitotoxic injury stimulates pro-drug-induced 7-chlorokynurenate formation in the rat striatum in vivo. Neuroscience letters 20010525
Relapse to cocaine-seeking after hippocampal theta burst stimulation. Science (New York, N.Y.) 20010511
Effect of the glycine modulatory site of the N-methyl-D-aspartate receptor on synaptic responses in kitten visual cortex. Neuroscience letters 20010504
6-Hydroxykynurenic acid and kynurenic acid differently antagonise AMPA and NMDA receptors in hippocampal neurones. Journal of neurochemistry 20010501
Protein peroxidation processes in bovine retained and not-retained placenta. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20010501
Changes in kynurenic, anthranilic, and quinolinic acid concentrations in rat brain tissue during development. Neurochemical research 20010501
Optical recording of spreading depression in rat neocortical slices. Brain research 20010420
Kynurenic acid antagonists and kynurenine pathway inhibitors. Expert opinion on investigational drugs 20010401
Ionic mechanisms of aglycemic axon injury in mammalian central white matter. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010401
Fast kinetics of exocytosis revealed by simultaneous measurements of presynaptic capacitance and postsynaptic currents at a central synapse. Neuron 20010401
Amphetamine-stimulated cortical acetylcholine release: role of the basal forebrain. Brain research 20010309
NMDA-responsible, APV-insensitive receptor in cultured human astrocytes. Life sciences 20010302
Basal forebrain glutamatergic modulation of cortical acetylcholine release. Synapse (New York, N.Y.) 20010301
Synapse-specific contribution of the variation of transmitter concentration to the decay of inhibitory postsynaptic currents. Biophysical journal 20010301
Anoxic depolarization mediates acute damage independent of glutamate in neocortical brain slices. Cerebral cortex (New York, N.Y. : 1991) 20010301
Evidence for glutamate receptor mediated transmission at mechanoreceptors in the skin. Neuroreport 20010212
Kynurenic acid influences the respiratory parameters of rat heart mitochondria. Pharmacology 20010201
Novelty-evoked elevations of nucleus accumbens dopamine: dependence on impulse flow from the ventral subiculum and glutamatergic neurotransmission in the ventral tegmental area. The European journal of neuroscience 20010201
Glutamatergic and GABAergic inputs to the RVL mediate cardiovascular adjustments to noxious stimulation. American journal of physiology. Regulatory, integrative and comparative physiology 20010201
Tonic excitatory input to the rostral ventrolateral medulla in Dahl salt-sensitive rats. Hypertension (Dallas, Tex. : 1979) 20010201
Tonic excitatory input to the rostral ventrolateral medulla in Dahl salt-sensitive rats. Hypertension (Dallas, Tex. : 1979) 20010201
Combining deconvolution and noise analysis for the estimation of transmitter release rates at the calyx of held. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115
Quantitative relationship between transmitter release and calcium current at the calyx of held synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115
Effect of extracellular long-time microperfusion of high concentrations of glutamate and glycine on picrotoxin seizure thresholds in the hippocampus of freely moving rats. Brain research 20010105
Endogenous neurotoxins from tryptophan. Toxicon : official journal of the International Society on Toxinology 20010101
Regional changes in kynurenic acid, quinolinic acid, and glial fibrillary acidic protein concentrations in the fetal sheep brain after experimentally induced placental insufficiency. American journal of obstetrics and gynecology 20010101
Pharmacologically elevated levels of endogenous kynurenic acid prevent nicotine-induced activation of nigral dopamine neurons. Naunyn-Schmiedeberg's archives of pharmacology 20010101
Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated stimulation of glutamate and GABA release in the rat striatum in vivo: a dual-label microdialysis study. Neuroscience 20010101
Glutamate regulates the spontaneous and evoked release of dopamine in the rat striatum. Neuroscience 20010101
Co-transmitter function of ATP in central catecholaminergic neurons of the rat. Neuroscience 20010101
Kynurenine 3-mono-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis. Neuroscience 20010101
Evidence for intraocular synthesis of kynurenic acid, a putative endogenous neuroprotectant. Ophthalmic research 20010101
Effects of nicotine on head-shakes and tryptophan metabolites. Psychopharmacology 20010101
Attenuation of morphine dependence and withdrawal by glycine B site antagonists in rats. Pharmacology, biochemistry, and behavior 20010101
Conjugation with L-Glutamate for in vivo brain drug delivery. Journal of drug targeting 20010101
Possible involvement of kynurenamines in the pathogenesis of cataract in diabetic patients. Medical science monitor : international medical journal of experimental and clinical research 20010101
Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons. Amino acids 20010101
Intraretinal analysis of the a-wave of the electroretinogram (ERG) in dark-adapted intact cat retina. Visual neuroscience 20010101
Na(+)-K(+)-ATPase inhibition and depolarization induce glutamate release via reverse Na(+)-dependent transport in spinal cord white matter. Neuroscience 20010101
Microtubule-associated protein 2 phosphorylation is decreased in the human epileptic temporal lobe cortex. Neuroscience 20010101
Gamma oscillation underlies hyperthermia-induced epileptiform-like spikes in immature rat hippocampal slices. BMC neuroscience 20010101
N-cholinergic facilitation of glutamate release from an individual retinotectal fiber in frog. Visual neuroscience 20010101
N(G)-nitro-L-arginine and its methyl ester inhibit brain synthesis of kynurenic acid possibly via nitric oxide-independent mechanism. Polish journal of pharmacology 20010101
Accumulation of toxic products degradation of kynurenine in hemodialyzed patients. International urology and nephrology 20010101
Kynurenic acid does not protect against nicotine-induced seizures in mice. Polish journal of pharmacology 20000101
The role of striatal glutamate receptors in models of Parkinson's disease. Amino acids 19980101
Antagonism of convulsions but failure to enhance GABA(A) receptor function by felbamate in mice tolerant to diazepam. Neurochemical research 19970601
Recovery of decreased seizure threshold for pentylenetetrazole during diazepam withdrawal by NMDA receptor antagonists. European journal of pharmacology 19970411
Anticonvulsant activity of 5,7DCKA, NBQX, and felbamate against some chemoconvulsants in DBA/2 mice. Pharmacology, biochemistry, and behavior 19961001
Excitoprotective effect of felbamate in cultured cortical neurons. Brain research 19951224
Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice. Brain research 19950206
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice. European journal of pharmacology 19940901
Glycine site antagonists abolish dopamine D2 but not D1 receptor mediated catalepsy in rats. Journal of neural transmission. General section 19940101
Some central effects of kynurenic acid, 7-chlorokynurenic acid and 5,7- dichloro-kynurenic acid, glycine site antagonists. Polish journal of pharmacology 19940101
Involvement of inhibitory and excitatory neurotransmitters in levofloxacin- and ciprofloxacin-induced convulsions in mice. Antimicrobial agents and chemotherapy 19930901
Sympathetic and metabolic mechanisms of the cerebrovasomotor function of the caudal ventrolateral medulla in rats. Neuroscience 19921001
4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor. Journal of medicinal chemistry 19920529
Inhibition of cocaine intoxication by excitatory amino acid receptor antagonists. Annals of the New York Academy of Sciences 19920511
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