Therapeutic drug monitoring of thiopurine metabolites in adult thiopurine tolerant IBD patients on maintenance therapy.

Journal of Crohn's & colitis 20120701

Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells.

Journal of medicinal chemistry 20120223

Microwave-promoted 'one-pot' synthesis of 4-nitrobenzylthioinosine analogues using thiourea as a sulfur precursor.

Chemistry, an Asian journal 20120102

Insulin-increased L-arginine transport requires A(2A) adenosine receptors activation in human umbilical vein endothelium.

PloS one 20120101

Adenosine negatively regulates duodenal motility in mice: role of A(1) and A(2A) receptors.

British journal of pharmacology 20111101

The effect of ITPA polymorphisms on the enzyme kinetic properties of human erythrocyte inosine triphosphatase toward its substrates ITP and 6-Thio-ITP.

Nucleosides, nucleotides & nucleic acids 20111101

Behavioral effects of elevated expression of human equilibrative nucleoside transporter 1 in mice.

Behavioural brain research 20111010

Expression of human equilibrative nucleoside transporter 1 in mouse neurons regulates adenosine levels in physiological and hypoxic-ischemic conditions.

Journal of neurochemistry 20110701

The role of inosine-5'-monophosphate dehydrogenase in thiopurine metabolism in patients with inflammatory bowel disease.

Therapeutic drug monitoring 20110401

Variability in transport and biotransformation of cytarabine is associated with its toxicity in peripheral blood mononuclear cells.

Pharmacogenomics 20110401

Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers.

Molecular cancer therapeutics 20110301

Membrane transport of sepiapterin and dihydrobiopterin by equilibrative nucleoside transporters: a plausible gateway for the salvage pathway of tetrahydrobiopterin biosynthesis.

Molecular genetics and metabolism 20110101

Antimutagenic, antigenotoxic and antioxidant activities of phenolic-enriched extracts from Teucrium ramosissimum: combination with their phytochemical composition.

Environmental toxicology and pharmacology 20110101

Testicular expression of Adora3i2 in Adora3 knockout mice reveals a role of mouse A3Ri2 and human A3Ri3 adenosine receptors in sperm.

The Journal of biological chemistry 20101029

Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: biological activities and selective toxicities.

Biochemical pharmacology 20101001

Differential expression of functional nucleoside transporters in non-differentiated and differentiated human endothelial progenitor cells.

Placenta 20101001

Characterization of mammalian equilibrative nucleoside transporters (ENTs) by mass spectrometry.

Protein expression and purification 20100901

Photoreactivity of carboxylated single-walled carbon nanotubes in sunlight: reactive oxygen species production in water.

Environmental science & technology 20100901

Biodistribution and uptake of 3'-deoxy-3'-fluorothymidine in ENT1-knockout mice and in an ENT1-knockdown tumor model.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901

Improved syntheses of 5'-S-(2-aminoethyl)-6-N-(4-nitrobenzyl)-5'-thioadenosine (SAENTA), analogues, and fluorescent probe conjugates: analysis of cell-surface human equilibrative nucleoside transporter 1 (hENT1) levels for prediction of the antitumor efficacy of gemcitabine.

Journal of medicinal chemistry 20100826

Excitatory synaptic transmission in the spinal substantia gelatinosa is under an inhibitory tone of endogenous adenosine.

Neuroscience letters 20100614

ENT1 regulates ethanol-sensitive EAAT2 expression and function in astrocytes.

Alcoholism, clinical and experimental research 20100601

Structure-activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase.

Bioorganic & medicinal chemistry 20100515

Immunomodulatory effects of proanthocyanidin A-1 derived in vitro from Rhododendron spiciferum.

Fitoterapia 20100301

Kinetic study of anti-viral ribavirin uptake mediated by hCNT3 and hENT1 in Xenopus laevis oocytes.

Biophysical chemistry 20100301

Anti-adipogenesis by 6-thioinosine is mediated by downregulation of PPAR gamma through JNK-dependent upregulation of iNOS.

Cellular and molecular life sciences : CMLS 20100201

Characterisation and utility of thiopurine methyltransferase and thiopurine metabolite measurements in autoimmune hepatitis.

Journal of hepatology 20100101

Human erythrocyte nucleoside transporter ENT1 functions at ice-cold temperatures.

Drug metabolism and pharmacokinetics 20100101

Captopril and 6-mercaptopurine: whose SH possesses higher antioxidant ability?

European journal of medicinal chemistry 20091201

Determination of 6-benzylthioinosine in mouse and human plasma by liquid chromatography-tandem mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091115

Photocycloaddition of the T1 excited state of thioinosine to uridine and adenosine.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20091001

Negative crosstalk between M1 and M2 muscarinic autoreceptors involves endogenous adenosine activating A1 receptors at the rat motor endplate.

Neuroscience letters 20090814

Prevention of early loss of transplanted islets in the liver of mice by adenosine.

Transplantation 20090715

Inhibitory effect of nonsteroidal anti-inflammatory drugs on adenosine transport in vascular smooth muscle cells.

European journal of pharmacology 20090610

Metformin prevents myocardial reperfusion injury by activating the adenosine receptor.

Journal of cardiovascular pharmacology 20090501

The role of the equilibrative nucleoside transporter 1 (ENT1) in transport and metabolism of ribavirin by human and wild-type or Ent1-/- mouse erythrocytes.

The Journal of pharmacology and experimental therapeutics 20090401

Modulation of gamma oscillations by endogenous adenosine through A1 and A2A receptors in the mouse hippocampus.

Neuropharmacology 20090201

Identification of a novel point mutation in ENT1 that confers resistance to Ara-C in human T cell leukemia CCRF-CEM cells.

FEBS letters 20090122

CoMFA and CoMSIA 3D-QSAR studies on S(6)-(4-nitrobenzyl)mercaptopurine riboside (NBMPR) analogs as inhibitors of human equilibrative nucleoside transporter 1 (hENT1).

Bioorganic & medicinal chemistry letters 20090115

Efficacy of the tubercidin antileishmania action associated with an inhibitor of the nucleoside transport.

Parasitology research 20090101

Contribution of Na+-independent nucleoside transport to ribavirin uptake in the rat intestine and human epithelial LS180 cells.

European journal of pharmacology 20081228

The role of ecto-5'-nucleotidase/CD73 in glioma cell line proliferation.

Molecular and cellular biochemistry 20081201

Enhancing brain adenosine signaling with the nucleoside transport blocker NBTI (S-(4-nitrobenzyl)-6-theoinosine) mimics the effects of inescapable shock on later shuttle-escape performance in rats.

Behavioral neuroscience 20081201

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal of medicinal chemistry 20081113

7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: activities and selective toxicities.

Biochemical pharmacology 20081015

Imatinib inhibition of fludarabine uptake in T-lymphocytes.

Cancer chemotherapy and pharmacology 20080901

Mutation of Trp29 of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity.

The Biochemical journal 20080901

Structure-activity relationships of 7-deaza-6-benzylthioinosine analogues as ligands of Toxoplasma gondii adenosine kinase.

Journal of medicinal chemistry 20080710

Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line.

American journal of physiology. Heart and circulatory physiology 20080601

Identification of 6-benzylthioinosine as a myeloid leukemia differentiation-inducing compound.

Cancer research 20080601

Cytotoxic activities of nucleoside and nucleobase analog drugs in malignant mesothelioma: characterization of a novel nucleobase transport activity.

Biochemical pharmacology 20080515

Potential of various drugs to inhibit nucleoside uptake in rat syncytiotrophoblast cell line, TR-TBT 18d-1.

Placenta 20080501

Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity.

Bioorganic & medicinal chemistry 20080401

Kinetics of nucleoside uptake by the basolateral side of the sheep choroid plexus epithelium perfused in situ.

Experimental physiology 20080301

Generation of superoxide from reaction of 3H-1,2-dithiole-3-thione with thiols: implications for dithiolethione chemoprotection.

Molecular and cellular biochemistry 20080101

Adenosine uptake-dependent C6 cell growth inhibition.

European journal of pharmacology 20071222

Novel C2-purine position analogs of nitrobenzylmercaptopurine riboside as human equilibrative nucleoside transporter 1 inhibitors.

Bioorganic & medicinal chemistry 20071215

Nucleoside and nucleobase transporters of primary human cardiac microvascular endothelial cells: characterization of a novel nucleobase transporter.

American journal of physiology. Heart and circulatory physiology 20071201

Nucleoside transporter expression and activity is regulated during granulocytic differentiation of NB4 cells in response to all-trans-retinoic acid.

Leukemia research 20070701

Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney.

American journal of physiology. Renal physiology 20070701

Cardioprotective effects of novel tetrahydroisoquinoline analogs of nitrobenzylmercaptopurine riboside in an isolated perfused rat heart model of acute myocardial infarction.

American journal of physiology. Heart and circulatory physiology 20070601

Residues 334 and 338 in transmembrane segment 8 of human equilibrative nucleoside transporter 1 are important determinants of inhibitor sensitivity, protein folding, and catalytic turnover.

The Journal of biological chemistry 20070511

Nucleoside transporter expression and adenosine uptake in the rat cochlea.

Neuroreport 20070212

Pancytopenia due to high 6-methylmercaptopurine levels in a 6-mercaptopurine treated patient with Crohn's disease.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20070201

Characterization of resistance to cytosine arabinoside (Ara-C) in NALM-6 human B leukemia cells.

Clinica chimica acta; international journal of clinical chemistry 20070201

Influence of hyperthyroidism on the effect of adenosine transport blockade assessed by a novel method in guinea pig atria.

Cell biochemistry and biophysics 20070101

Insulin restores glucose inhibition of adenosine transport by increasing the expression and activity of the equilibrative nucleoside transporter 2 in human umbilical vein endothelium.

Journal of cellular physiology 20061201

Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress.

Diabetes 20061001

In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients.

British journal of cancer 20060807

Alkyl-fluorinated thymidine derivatives for imaging cell proliferation I. The in vitro evaluation of some alkyl-fluorinated thymidine derivatives.

Nuclear medicine and biology 20060801

The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine.

Molecular pharmacology 20060701

Genetic interdependence of adenosine and dopamine receptors: evidence from receptor knockout mice.

Neuroscience 20060512

Characterization of novel Na+-dependent nucleobase transport systems at the blood-testis barrier.

American journal of physiology. Endocrinology and metabolism 20060501

Studies of nucleoside transporters using novel autofluorescent nucleoside probes.

Biochemistry 20060131

In-vitro and in-vivo anti-cancer activity of a novel gemcitabine-cardiolipin conjugate.

Anti-cancer drugs 20060101

Effect of nucleoside transport blockade on the interstitial adenosine level characterized by a novel method in guinea pig atria.

Journal of cardiovascular pharmacology 20060101

Effects on sleep of microdialysis of adenosine A1 and A2a receptor analogs into the lateral preoptic area of rats.

American journal of physiology. Regulatory, integrative and comparative physiology 20051201

Localization of the NBMPR-sensitive equilibrative nucleoside transporter, ENT1, in the rat dorsal root ganglion and lumbar spinal cord.

Brain research 20051019

Adenosine down-regulates giant depolarizing potentials in the developing rat hippocampus by exerting a negative control on glutamatergic inputs.

Journal of neurophysiology 20051001

Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway.

Cell proliferation 20051001

Adsorption of 6-mercaptopurine and 6-mercaptopurine-ribosideon silver colloid: a pH-dependent surface-enhanced Raman spectroscopy and density functional theory study. II. 6-mercaptopurine-riboside.

Biopolymers 20050815

Equilibrative nucleoside transporter 1 expression is downregulated by hypoxia in human umbilical vein endothelium.

Circulation research 20050708

D-Glucose upregulates adenosine transport in cultured human aortic smooth muscle cells.

American journal of physiology. Heart and circulatory physiology 20050601

6-Benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: activities and selective toxicities.

Biochemical pharmacology 20050515

Subtype-specific regulation of equilibrative nucleoside transporters by protein kinase CK2.

The Biochemical journal 20050301

Residues Met89 and Ser160 in the human equilibrative nucleoside transporter 1 affect its affinity for adenosine, guanosine, S6-(4-nitrobenzyl)-mercaptopurine riboside, and dipyridamole.

Molecular pharmacology 20050301

Astrocytes and neurons: different roles in regulating adenosine levels.

Neurological research 20050301

Nucleoside transport at the blood-testis barrier studied with primary-cultured sertoli cells.

The Journal of pharmacology and experimental therapeutics 20050201

An investigation of binding sites for paracetamol in the mouse brain and spinal cord.

European journal of pharmacology 20050131

Inhibition of nucleoside transport proteins by C8-alkylamine-substituted purines.

Journal of medicinal chemistry 20050113

Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes.

Neuroscience research 20050101

Brain penetration of synthetic adenosine A1 receptor agonists in situ: role of the rENT1 nucleoside transporter and binding to blood constituents.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050101

Equilibrative nucleoside transporter 2 is expressed in human umbilical vein endothelium, but is not involved in the inhibition of adenosine transport induced by hyperglycaemia.

Placenta 20050101

Fine tuning of rabbit equilibrative nucleoside transporter activity by an alternatively spliced variant.

Journal of drug targeting 20050101

CPEC induces erythroid differentiation of human myeloid leukemia K562 cells through CTP depletion and p38 MAP kinase.

Leukemia 20041101

Quantitative autoradiography of adenosine receptors and NBTI-sensitive adenosine transporters in the brains of mice deficient in the preproenkephalin gene.

Brain research 20041029

Nucleoside transporter subtype expression and function in rat skeletal muscle microvascular endothelial cells.

British journal of pharmacology 20040901

Determinants of sensitivity and resistance to gemcitabine: the roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer.

Cancer science 20040901

Hypoxia induces adenosine release from the rat carotid body.

Journal of neurochemistry 20040601

Renal secretion of the antiviral nucleoside analog AM188 is inhibited by probenecid, p-aminohippuric acid, and cimetidine in the isolated perfused rat kidney.

Pharmaceutical research 20040601

Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1.

The Biochemical journal 20040515

Novel halogenated nitrobenzylthioinosine analogs as es nucleoside transporter inhibitors.

Bioorganic & medicinal chemistry letters 20040503

Pharmacological analysis and molecular cloning of the canine equilibrative nucleoside transporter 1.

European journal of pharmacology 20040426

Synthesis, biological activity and molecular modeling of 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase.

Journal of medicinal chemistry 20040408

Interaction of the novel adenosine uptake inhibitor 3-[1-(6,7-diethoxy-2-morpholinoquinazolin-4-yl)piperidin-4-yl]-1,6-dimethyl-2,4(1H,3H)-quinazolinedione hydrochloride (KF24345) with the es and ei subtypes of equilibrative nucleoside transporters.

The Journal of pharmacology and experimental therapeutics 20040301

Transient in vivo selection of transduced peripheral blood cells using antifolate drug selection in rhesus macaques that received transplants with hematopoietic stem cells expressing dihydrofolate reductase vectors.

Blood 20040201

Inhibition of glucose uptake in murine cardiomyocyte cell line HL-1 by cardioprotective drugs dilazep and dipyridamole.

American journal of physiology. Heart and circulatory physiology 20040201

Adenosine transport in peripheral blood lymphocytes from Lesch-Nyhan patients.

The Biochemical journal 20040201

Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep.

Biochemical pharmacology 20040201

Extracellular inosine is modulated by H2O2 and protects sertoli cells against lipoperoxidation and cellular injury.

Free radical research 20040101

Mechanism of ganciclovir uptake by rabbit retina and human retinal pigmented epithelium cell line ARPE-19.

Current eye research 20040101

Nitrobenzylthioinosine (NBMPR) binding and nucleoside transporter ENT1 mRNA expression after prolonged wakefulness and recovery sleep in the cortex and basal forebrain of rat.

Journal of sleep research 20031201

Positive inotropic effect of the inhibition of cyclic GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase (PDE2) on guinea pig left atria in eu- and hyperthyroidism.

General physiology and biophysics 20031201

Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.

Neuropharmacology 20031001

Endogenous adenosine modulation of 22Na uptake by rat brain synaptosomes.

Neurochemical research 20031001

Functional differences in nucleoside and nucleobase transporters expressed on the rabbit corneal epithelial cell line (SIRC) and isolated rabbit cornea.

AAPS pharmSci 20030601

Probing the activation site of ribonuclease L with new N6-substituted 2',5'-adenylate trimers.

Bioorganic & medicinal chemistry 20030501

Control of glutamatergic neurotransmission in the rat spinal dorsal horn by the nucleoside transporter ENT1.

The Journal of physiology 20030415

Molecular and biochemical events during differentiation of the HD3 chicken erythroblastic cell line.

The international journal of biochemistry & cell biology 20030401

Inhibition of nucleoside transport by new analogues of nitrobenzylthioinosine.

Bioorganic & medicinal chemistry 20030320

5-Aminoimidazole-4-carboxamide riboside induces apoptosis in Jurkat cells, but the AMP-activated protein kinase is not involved.

The Biochemical journal 20030315

Trimetrexate inhibits progression of the murine 32Dp210 model of chronic myeloid leukemia in animals expressing drug-resistant dihydrofolate reductase.

Cancer research 20030315

Diurnal regulation of arylalkylamine N-acetyltransferase activity in chicken retinal cells in vitro: analysis of culture conditions.

Molecular vision 20030305

Extracellular purines from cells of seminiferous tubules.

Molecular and cellular biochemistry 20030301

Synthesis and flow cytometric evaluation of novel 1,2,3,4-tetrahydroisoquinoline conformationally constrained analogues of nitrobenzylmercaptopurine riboside (NBMPR) designed for probing its conformation when bound to the es nucleoside transporter.

Journal of medicinal chemistry 20030227

Kinetics and mechanism for platination of thione-containing nucleotides and oligonucleotides: evaluation of the salt dependence.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20030101

Functional expression of a sodium dependent nucleoside transporter on rabbit cornea: Role in corneal permeation of acyclovir and idoxuridine.

Current eye research 20030101

Convenient synthesis of oligodeoxynucleotides containing 2'-deoxy-6-thioinosine.

Nucleosides, nucleotides & nucleic acids 20030101

2'-Deoxyadenosine causes apoptotic cell death in a human colon carcinoma cell line.

Journal of biochemical and molecular toxicology 20030101

Quantitative autoradiography of adenosine receptors and NBTI-sensitive adenosine transporters in the brains and spinal cords of mice deficient in the mu-opioid receptor gene.

Brain research 20020705

Complex effects of sulfhydryl reagents on ligand interactions with nucleoside transporters: evidence for multiple populations of ENT1 transporters with differential sensitivities to N-ethylmaleimide.

Archives of biochemistry and biophysics 20020701

Differences between children and adults in thiopurine methyltransferase activity and metabolite formation during thiopurine therapy: possible role of concomitant methotrexate.

Therapeutic drug monitoring 20020601

Inhibition of nitrobenzylthioinosine-sensitive adenosine transport by elevated D-glucose involves activation of P2Y2 purinoceptors in human umbilical vein endothelial cells.

Circulation research 20020322

Inhibition of shiga toxin cytotoxicity in human renal cortical epithelial cells by nitrobenzylthioinosine.

The Journal of infectious diseases 20020315

A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine.

Biochemistry 20020205

The kinetics of hypoxanthine transport across the perfused choroid plexus of the sheep.

Brain research 20020125

Mutation of residue 33 of human equilibrative nucleoside transporters 1 and 2 alters sensitivity to inhibition of transport by dilazep and dipyridamole.

The Journal of biological chemistry 20020104

In vivo selection of antifolate-resistant transgenic hematopoietic stem cells in a murine bone marrow transplant model.

The Journal of pharmacology and experimental therapeutics 20020101

Immunohistochemical variation of human equilibrative nucleoside transporter 1 protein in primary breast cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research 20020101

Nucleoside transport inhibitors, dipyridamole and p-nitrobenzylthioinosine, selectively potentiate the antitumor activity of NB1011.

Anti-cancer drugs 20020101

Transport characteristics of HL-1 cells: a new model for the study of adenosine physiology in cardiomyocytes.

Biochemistry and cell biology = Biochimie et biologie cellulaire 20020101

Regulation of K(+) current in human airway epithelial cells by exogenous and autocrine adenosine.

American journal of physiology. Cell physiology 20011201

Extracellular formation and uptake of adenosine during skeletal muscle contraction in the rat: role of adenosine transporters.

The Journal of physiology 20011201

Comparative pharmacokinetics of oral 6-mercaptopurine and intravenous 6-mercaptopurine riboside in children.

Pediatrics international : official journal of the Japan Pediatric Society 20011201

Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs.

The Journal of biological chemistry 20011130

Nucleoside transporter subtype expression: effects on potency of adenosine kinase inhibitors.

British journal of pharmacology 20011101

Equilibrative nucleoside transporters: mapping regions of interaction for the substrate analogue nitrobenzylthioinosine (NBMPR) using rat chimeric proteins.

Biochemistry 20010710

Characterization of an NBTI-sensitive equilibrative nucleoside transporter in vascular smooth muscle.

Journal of molecular and cellular cardiology 20010601

Developmental regulation of the concentrative nucleoside transporters CNT1 and CNT2 in rat liver.

Journal of hepatology 20010601

Long-term activation of adenosine A(2a) receptors blocks glutamate excitotoxicity in cultures of avian retinal neurons.

Brain research 20010511

Characterization of nucleoside transport systems in cultured rat epididymal epithelium.

American journal of physiology. Cell physiology 20010501

Ontogenic and longitudinal activity of Na(+)-nucleoside transporters in the human intestine.

American journal of physiology. Gastrointestinal and liver physiology 20010301

Synthesis using ring closure metathesis and effect on nucleoside transport of a (N)-methanocarba S-(4-nitrobenzyl)thioinosine derivative.

Organic letters 20010222

Hypoxanthine transport in human tumour cell lines: relationship to the inhibition of hypoxanthine rescue by dipyridamole.

Biochemical pharmacology 20010215

Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).

The Journal of biological chemistry 20010126

Identification of Cys140 in helix 4 as an exofacial cysteine residue within the substrate-translocation channel of rat equilibrative nitrobenzylthioinosine (NBMPR)-insensitive nucleoside transporter rENT2.

The Biochemical journal 20010115

Cloning of a novel isoform of the mouse NBMPR-sensitive equilibrative nucleoside transporter (ENT1) lacking a putative phosphorylation site.

Gene 20010110

Nitrobenzylthioinosine (NBT), a nucleoside transport inhibitor, protects against Shiga toxin cytotoxicity in human microvascular endothelial cells.

Endothelium : journal of endothelial cell research 20010101

Induction of apoptosis in human leukemia cells by 3-deazaadenosine is mediated by caspase-3-like activity.

Experimental & molecular medicine 20001231

Interaction of a series of draflazine analogues with equilibrative nucleoside transporters: species differences and transporter subtype selectivity.

Naunyn-Schmiedeberg's archives of pharmacology 20000401

Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer.

Cancer research 20000401

Metabolism and selective toxicity of 6-nitrobenzylthioinosine in Toxoplasma gondii.

Antimicrobial agents and chemotherapy 19991001

Nucleoside transport in human colonic epithelial cell lines: evidence for two Na+-independent transport systems in T84 and Caco-2 cells.

Biochimica et biophysica acta 19990609

Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.

The Journal of neuroscience : the official journal of the Society for Neuroscience 19981001

Chimeric constructs between human and rat equilibrative nucleoside transporters (hENT1 and rENT1) reveal hENT1 structural domains interacting with coronary vasoactive drugs.

The Journal of biological chemistry 19980821

Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta.

The Biochemical journal 19971215

Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues.

The Journal of biological chemistry 19971107

Functional characterization of a recombinant sodium-dependent nucleoside transporter with selectivity for pyrimidine nucleosides (cNT1rat) by transient expression in cultured mammalian cells.

The Biochemical journal 19960715

Synthesis and antiviral activity of certain carbamoylpyrrolopyrimidine and pyrazolopyrimidine nucleosides.

Journal of medicinal chemistry 19821101

Purine analogs as potential anticytomegalovirus agents.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19690901