Home Carboxys methyl (1R,4aS,7aS)-1-hydroxy-7-(hydroxymethyl)-1H,4aH,5H,7aH-cyclopenta[c]pyran-4-carboxylate

methyl (1R,4aS,7aS)-1-hydroxy-7-(hydroxymethyl)-1H,4aH,5H,7aH-cyclopenta[c]pyran-4-carboxylate

CAS No.:
6902-77-8
Catalog Number:
AG00F9W9
Molecular Formula:
C11H14O5
Molecular Weight:
226.2259
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
>98%(HPLC)powder
In Stock USA
United States
$98
- +
1g
96%
In Stock USA
United States
$113
- +
5g
96%
In Stock USA
United States
$325
- +
10g
96%
In Stock USA
United States
$600
- +
25g
96%
In Stock USA
United States
$1200
- +
Product Description
Catalog Number:
AG00F9W9
Chemical Name:
methyl (1R,4aS,7aS)-1-hydroxy-7-(hydroxymethyl)-1H,4aH,5H,7aH-cyclopenta[c]pyran-4-carboxylate
CAS Number:
6902-77-8
Molecular Formula:
C11H14O5
Molecular Weight:
226.2259
MDL Number:
MFCD00888600
IUPAC Name:
methyl (1R,4aS,7aS)-1-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
InChI:
InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1
InChI Key:
AZKVWQKMDGGDSV-BCMRRPTOSA-N
SMILES:
COC(=O)C1=CO[C@H]([C@H]2[C@@H]1CC=C2CO)O
UNII:
A3V2NE52YG
Properties
Complexity:
357  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
226.084g/mol
Formal Charge:
0
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
226.228g/mol
Monoisotopic Mass:
226.084g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
76A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.7  
Literature
Title Journal
Genipin inhibits the invasion and migration of colon cancer cells by the suppression of HIF-1α accumulation and VEGF expression. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180601
Genipin protects the liver from ischemia/reperfusion injury by modulating mitochondrial quality control. Toxicology and applied pharmacology 20170801
Downregulation of proteins involved in the endoplasmic reticulum stress response and Nrf2-ARE signaling in lymphoblastoid cells of spinocerebellar ataxia type 17. Journal of neural transmission (Vienna, Austria : 1996) 20140601
Chitosan-caffeic acid-genipin films presenting enhanced antioxidant activity and stability in acidic media. Carbohydrate polymers 20130102
Strain stiffening in collagen I networks. Biopolymers 20130101
Encapsulation of protein microfiber networks supporting pancreatic islets. Journal of biomedical materials research. Part A 20121201
Electrospun hydroxyapatite-containing chitosan nanofibers crosslinked with genipin for bone tissue engineering. Biomaterials 20121201
New crosslinkers for electrospun chitosan fibre mats. I. Chemical analysis. Journal of the Royal Society, Interface 20121007
Vacuum-assisted infiltration of chitosan or polycaprolactone as a structural reinforcement for sintered cancellous bovine bone graft. Journal of biomedical materials research. Part A 20121001
Bioactive glass/polymer composite scaffolds mimicking bone tissue. Journal of biomedical materials research. Part A 20121001
Role of mitochondrial uncoupling protein 2 in cancer cell resistance to gemcitabine. Biochimica et biophysica acta 20121001
G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization. Human molecular genetics 20121001
Using genipin-crosslinked acellular porcine corneal stroma for cosmetic corneal lens implants. Biomaterials 20121001
Whole globe inflation testing of exogenously crosslinked sclera using genipin and methylglyoxal. Experimental eye research 20121001
'From safe source to safe sink' development of colorimetric assay for gabapentin in bulk drug and capsules using naturally derived genipin. Talanta 20120915
Genipin inhibits lipopolysaccharide-induced acute systemic inflammation in mice as evidenced by nuclear factor-κB bioluminescent imaging-guided transcriptomic analysis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901
Synthesis of stable genipin derivatives and studies of their neuroprotective activity in PC12 cells. ChemMedChem 20120901
The effect of procyanidine crosslinking on the properties of the electrospun gelatin membranes. Biofabrication 20120901
Novel silk fibroin/elastin wound dressings. Acta biomaterialia 20120801
Hydrogel membranes based on genipin-cross-linked chitosan blends for corneal epithelium tissue engineering. Journal of materials science. Materials in medicine 20120801
Intra-articular delivery of genipin cross-linked chitosan microspheres of flurbiprofen: preparation, characterization, in vitro and in vivo studies. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120801
Collagen-based fibrillar multilayer films cross-linked by a natural agent. Biomacromolecules 20120709
HPLC-MS/MS method to determine genipin in rat plasma after hydrolysis with sulfatase and its application to a pharmacokinetic study. Biomedical chromatography : BMC 20120701
Engineering endostatin-expressing cartilaginous constructs using injectable biopolymer hydrogels. Acta biomaterialia 20120701
Exogenous collagen cross-linking recovers tendon functional integrity in an experimental model of partial tear. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20120601
Impact of metal oxide nanoparticles on oral release properties of pH-sensitive hydrogel nanocomposites. International journal of biological macromolecules 20120601
Electrospinning of amphipathic chitosan nanofibers for surgical implants application. Journal of nanoscience and nanotechnology 20120601
Reactions between β-lactoglobulin and genipin: kinetics and characterization of the products. Journal of agricultural and food chemistry 20120502
Long-term changes to in vitro preserved bioengineered human trachea and their implications for decellularized tissues. Biomaterials 20120501
Uncoupling protein 2 negatively regulates glucose-induced glucagon-like peptide 1 secretion. Journal of molecular endocrinology 20120401
BDNF blended chitosan scaffolds for human umbilical cord MSC transplants in traumatic brain injury therapy. Biomaterials 20120401
[The preparation and evaluation of tissue inducible nerve guide conduit]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20120401
Biotransformation of geniposide by human intestinal microflora on cytotoxicity against HepG2 cells. Toxicology letters 20120325
Eucommia ulmoides bark protects against renal injury in cadmium-challenged rats. Journal of medicinal food 20120301
Fabrication and evaluation of biomimetic-synthetic nanofibrous composites for soft tissue regeneration. Cell and tissue research 20120301
Modelling the self-assembly of elastomeric proteins provides insights into the evolution of their domain architectures. PLoS computational biology 20120301
A comparative study on mechanical and biochemical properties of bovine pericardium after single or double crosslinking treatment. Korean circulation journal 20120301
Role of metabolism by human intestinal microflora in geniposide-induced toxicity in HepG2 cells. Archives of pharmacal research 20120301
Anticalcification effects of decellularization, solvent, and detoxification treatment for genipin and glutaraldehyde fixation of bovine pericardium. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20120201
Genipin, a constituent of Gardenia jasminoides Ellis, induces apoptosis and inhibits invasion in MDA-MB-231 breast cancer cells. Oncology reports 20120201
Characterization and scanning electron microscopic investigation of crosslinked freeze dried gelatin matrices for study of drug diffusivity and release kinetics. Micron (Oxford, England : 1993) 20120201
[Establishment of the Chang liver cell line stably overexpressing human UCP2 gene and its effect on mitochondrial membrane potential and reactive oxygen species]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20120201
Gelatin-based emulsion gels for diffusion-controlled release applications. Journal of biomaterials science. Polymer edition 20120101
Preparation of a genipin blue from egg protein and genipin. Natural product research 20120101
Peripheral nerve repair of transplanted undifferentiated adipose tissue-derived stem cells in a biodegradable reinforced nerve conduit. Journal of biomedical materials research. Part A 20120101
Biomechanical and angiogenic properties of tissue-engineered rat trachea using genipin cross-linked decellularized tissue. Biomaterials 20120101
MAP Kinases and Prostate Cancer. Journal of signal transduction 20120101
Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus. Experimental diabetes research 20120101
Scaffolds in tendon tissue engineering. Stem cells international 20120101
Genipin attenuates sepsis by inhibiting Toll-like receptor signaling. Molecular medicine (Cambridge, Mass.) 20120101
Inhibition of STAT3 signaling and induction of SHP1 mediate antiangiogenic and antitumor activities of ergosterol peroxide in U266 multiple myeloma cells. BMC cancer 20120101
Swelling behaviour and controlled drug release from cross-linked κ-carrageenan/NaCMC hydrogel by diffusion mechanism. Journal of microencapsulation 20120101
A pH-sensitive multifunctional gene carrier assembled via layer-by-layer technique for efficient gene delivery. International journal of nanomedicine 20120101
Dietary blue pigments derived from genipin, attenuate inflammation by inhibiting LPS-induced iNOS and COX-2 expression via the NF-κB inactivation. PloS one 20120101
Applications of circular dichroism for structural analysis of gelatin and antimicrobial peptides. International journal of molecular sciences 20120101
Icariside II induces apoptosis in U937 acute myeloid leukemia cells: role of inactivation of STAT3-related signaling. PloS one 20120101
Xenogenic esophagus scaffolds fixed with several agents: comparative in vivo study of rejection and inflammation. Journal of biomedicine & biotechnology 20120101
Pseudomonas sp. as a Source of Medium Chain Length Polyhydroxyalkanoates for Controlled Drug Delivery: Perspective. International journal of microbiology 20120101
Elastic chitosan conduits with multiple channels and well defined microstructure. International journal of biological macromolecules 20120101
Corneal crosslinking with genipin, comparison with UV-riboflavin in ex-vivo model. Molecular vision 20120101
Chitosan-hyaluronate hybrid gel intraarticular injection delays osteoarthritis progression and reduces pain in a rat meniscectomy model as compared to saline and hyaluronate treatment. Advances in orthopedics 20120101
Biological Activities of Libidibia (Caesalpinia) ferrea var. parvifolia (Mart. ex Tul.) L. P. Queiroz Pod Preparations. Evidence-based complementary and alternative medicine : eCAM 20120101
Genipin inhibits mitochondrial uncoupling protein 2 expression and ameliorates podocyte injury in diabetic mice. PloS one 20120101
Genipin-crosslinked chitosan scaffolds and its efficacy in releasing anti-inflammatory medicine. Bio-medical materials and engineering 20120101
Up-regulation of TIMP-1 by genipin inhibits MMP-2 activities and suppresses the metastatic potential of human hepatocellular carcinoma. PloS one 20120101
Biocompatibility of genipin and glutaraldehyde cross-linked chitosan materials in the anterior chamber of the eye. International journal of molecular sciences 20120101
Comparison between two different methods of immobilizing NGF in poly(DL-lactic acid-co-glycolic acid) conduit for peripheral nerve regeneration by EDC/NHS/MES and genipin. Journal of biomedical materials research. Part A 20111215
Neuritogenic activity of a genipin derivative in retinal ganglion cells is mediated by retinoic acid receptor β expression through nitric oxide/S-nitrosylation signaling. Journal of neurochemistry 20111201
[Study on preparation of acellular matrix material fixed by oxidized sodium alginate and its cytocompatibility]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20111201
Composite fibrous matrices prepared by electrospinning with various volumes to control the amount of immobilized basic fibroblast growth factors and its in vitro bioactivity. Journal of controlled release : official journal of the Controlled Release Society 20111130
Genipin crosslinked gelatin nanofibers for tissue engineering. Journal of controlled release : official journal of the Controlled Release Society 20111130
Genipin-crosslinked N-carboxymethyl chitosan microcapsules prepared by electrostatic spray method. Journal of controlled release : official journal of the Controlled Release Society 20111130
Identification of metabolites of geniposide in rat urine using ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20111115
Novel use of biodegradable casein conduits for guided peripheral nerve regeneration. Journal of the Royal Society, Interface 20111107
Nerve conduits based on immobilization of nerve growth factor onto modified chitosan by using genipin as a crosslinking agent. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20111101
Comparative analysis of gelatin scaffolds crosslinked by genipin and silane coupling agent. International journal of biological macromolecules 20111101
Controlled gelation and degradation rates of injectable hyaluronic acid-based hydrogels through a double crosslinking strategy. Journal of tissue engineering and regenerative medicine 20111101
Enhancing effect of hydroxypropyl-β-cyclodextrin on the intestinal absorption process of genipin. Journal of agricultural and food chemistry 20111026
Chitosan nanogels by template chemical cross-linking in polyion complex micelle nanoreactors. Biomacromolecules 20111010
Calorimetric analysis of gelatine-glycosaminoglycans blend system. International journal of biological macromolecules 20111001
Functional finishing of aminated polyester using biopolymer-based polyelectrolyte microgels. Biotechnology journal 20111001
Cross-linked collagen sponges loaded with plant polyphenols with inhibitory activity towards chronic wound enzymes. Biotechnology journal 20111001
Iridoid-specific glucosyltransferase from Gardenia jasminoides. The Journal of biological chemistry 20110916
In situ forming chitosan hydrogels prepared via ionic/covalent co-cross-linking. Biomacromolecules 20110912
Effect of penicillin G on the biliary excretion of cholephilic compounds in rats. Journal of hepato-biliary-pancreatic sciences 20110901
Genipin up-regulates heme oxygenase-1 via PI3-kinase-JNK1/2-Nrf2 signaling pathway to enhance the anti-inflammatory capacity in RAW264.7 macrophages. Archives of biochemistry and biophysics 20110815
Casein-based formulations as promising controlled release drug delivery systems. Journal of controlled release : official journal of the Controlled Release Society 20110810
Radiological characterization and water equivalency of genipin gel for x-ray and electron beam dosimetry. Physics in medicine and biology 20110807
Comparison of the properties of lipase immobilized onto mesoporous resins by different methods. Applied biochemistry and biotechnology 20110701
In situ synthesis of polysaccharide nanoparticles via polyion complex of carboxymethyl cellulose and chitosan. Colloids and surfaces. B, Biointerfaces 20110701
Effect of genipin crosslinking on the optical spectral properties and structures of collagen hydrogels. ACS applied materials & interfaces 20110701
Superior cell delivery features of genipin crosslinked polymeric microcapsules: preparation, in vitro characterization and pro-angiogenic applications using human adipose stem cells. Molecular biotechnology 20110601
Signal transducer and activator of transcription 3 pathway mediates genipin-induced apoptosis in U266 multiple myeloma cells. Journal of cellular biochemistry 20110601
Genipin Selectively Inhibits TNF-α-activated VCAM-1 But Not ICAM-1 Expression by Upregulation of PPAR-γ in Human Endothelial Cells. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20110601
Study on genipin: a new alternative natural crosslinking agent for fixing heterograft tissue. The Korean journal of thoracic and cardiovascular surgery 20110601
Transformation of geniposide into genipin by immobilized β-glucosidase in a two-phase aqueous-organic system. Molecules (Basel, Switzerland) 20110524
Exogenous collagen crosslinking of the intervertebral disc restores joint stability after lumbar posterior decompression surgery. Spine 20110520
In vitro assessment of the differentiation potential of bone marrow-derived mesenchymal stem cells on genipin-chitosan conjugation scaffold with surface hydroxyapatite nanostructure for bone tissue engineering. Tissue engineering. Part A 20110501
Construction of a fluorescent nanostructured chitosan-hydroxyapatite scaffold by nanocrystallon induced biomimetic mineralization and its cell biocompatibility. ACS applied materials & interfaces 20110501
Genipin-crosslinked fibrin hydrogels as a potential adhesive to augment intervertebral disc annulus repair. European cells & materials 20110418
Effects of torsion on intervertebral disc gene expression and biomechanics, using a rat tail model. Spine 20110415
Electrospun gelatin nanofibers: optimization of genipin cross-linking to preserve fiber morphology after exposure to water. Acta biomaterialia 20110401
Fabrication of porous chitosan scaffolds for soft tissue engineering using dense gas CO2. Acta biomaterialia 20110401
Microwave-induced facile synthesis of water-soluble fluorogenic alginic acid derivatives. Carbohydrate research 20110401
Cytocompatibility study of a natural biomaterial crosslinker--Genipin with therapeutic model cells. Journal of biomedical materials research. Part B, Applied biomaterials 20110401
Apoptosis induced by genipin in human leukemia K562 cells: involvement of c-Jun N-terminal kinase in G₂/M arrest. Acta pharmacologica Sinica 20110401
Analysis of gelatin plasma substitutes in blood based on detection of hydroxyproline derivatives. Artificial cells, blood substitutes, and immobilization biotechnology 20110201
Surface modification of poly(ε-caprolactone) porous scaffolds using gelatin hydrogel as the tracheal replacement. Journal of tissue engineering and regenerative medicine 20110201
Potent inhibitor design against H1N1 swine influenza: structure-based and molecular dynamics analysis for M2 inhibitors from traditional Chinese medicine database. Journal of biomolecular structure & dynamics 20110201
Sciatic nerve repair by reinforced nerve conduits made of gelatin-tricalcium phosphate composites. Journal of biomedical materials research. Part A 20110201
Thermal analysis reveals differential effects of various crosslinkers on bovine annulus fibrosis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20110101
Optimization of protein crosslinking formulations for the treatment of degenerative disc disease. Spine 20110101
Electrospun silk fibroin-hydroxybutyl chitosan nanofibrous scaffolds to biomimic extracellular matrix. Journal of biomaterials science. Polymer edition 20110101
Optimization of suture-free laser-assisted vessel repair by solder-doped electrospun poly(ε-caprolactone) scaffold. Annals of biomedical engineering 20110101
Fibroblast and vascular endothelial growth factor coating of decellularized vascular grafts stimulates undesired giant cells and graft encapsulation in a rat model. Artificial organs 20110101
Effects of different cross-linking conditions on the properties of genipin-cross-linked chitosan/collagen scaffolds for cartilage tissue engineering. Journal of materials science. Materials in medicine 20110101
Genipin-crosslinked microcarriers mediating hepatocellular aggregates formation and functionalities. Journal of biomedical materials research. Part A 20110101
Crosslinking of gelatin-based drug carriers by genipin induces changes in drug kinetic profiles in vitro. Journal of materials science. Materials in medicine 20110101
Effect of nitrogen-rich cell culture surfaces on type X collagen expression by bovine growth plate chondrocytes. Biomedical engineering online 20110101
The addition of a pH-sensitive gel improves microemulsion stability for the targeted removal of colonic ammonia. BMC gastroenterology 20110101
Experimental and modeling study of collagen scaffolds with the effects of crosslinking and fiber alignment. International journal of biomaterials 20110101
Cellular model of Warburg effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin. PloS one 20110101
Preventive effect of geniposide on metabolic disease status in spontaneously obese type 2 diabetic mice and free fatty acid-treated HepG2 cells. Biological & pharmaceutical bulletin 20110101
Folic acid modified gelatine coated quantum dots as potential reagents for in vitro cancer diagnostics. Journal of nanobiotechnology 20110101
Transforming growth factor β₁ oppositely regulates the hypertrophic and contractile response to β-adrenergic stimulation in the heart. PloS one 20110101
Biomedical exploitation of chitin and chitosan via mechano-chemical disassembly, electrospinning, dissolution in imidazolium ionic liquids, and supercritical drying. Marine drugs 20110101
Enzyme-polymers conjugated to quantum-dots for sensing applications. Sensors (Basel, Switzerland) 20110101
Omentum-wrapped scaffold with longitudinally oriented micro-channels promotes axonal regeneration and motor functional recovery in rats. PloS one 20110101
Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives. Pharmacognosy reviews 20110101
[Genipin--uncoupling protein inhibitor--reduces the protective effect of ischemic preconditioning]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20110101
Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1. Nature 20101202
Formulation and characterization of silk sericin-PVA scaffold crosslinked with genipin. International journal of biological macromolecules 20101201
Genipin-crosslinked silk fibroin/hydroxybutyl chitosan nanofibrous scaffolds for tissue-engineering application. Journal of biomedical materials research. Part A 20101201
Ophthalmic drug-loaded N,O-carboxymethyl chitosan hydrogels: synthesis, in vitro and in vivo evaluation. Acta pharmacologica Sinica 20101201
Kinetic analysis of genipin degradation in aqueous solution. Natural product communications 20101201
[Influence of genipin and vitamin E on UCP2 and other correlation factors in non-alcoholic fatty liver disease]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20101201
The effects of exogenous crosslinking on hydration and fluid flow in the intervertebral disc subjected to compressive creep loading and unloading. Spine 20101115
Genipin-cross-linked collagen/chitosan biomimetic scaffolds for articular cartilage tissue engineering applications. Journal of biomedical materials research. Part A 20101101
Acellular dermal matrix graft: synergistic effect of rehydration and natural crosslinking on mechanical properties. Journal of biomedical materials research. Part B, Applied biomaterials 20101101
The influence of exogenous cross-linking and compressive creep loading on intradiscal pressure. Biomechanics and modeling in mechanobiology 20101001
Development of functional fibrous matrices for the controlled release of basic fibroblast growth factor to improve therapeutic angiogenesis. Tissue engineering. Part A 20101001
Long-acting genipin derivative protects retinal ganglion cells from oxidative stress models in vitro and in vivo through the Nrf2/antioxidant response element signaling pathway. Journal of neurochemistry 20101001
Characteristics and biocompatibility of a biodegradable genipin-cross-linked gelatin/β-tricalcium phosphate reinforced nerve guide conduit. Journal of biomedical materials research. Part B, Applied biomaterials 20101001
Gelatin microspheres crosslinked with genipin for local delivery of growth factors. Journal of tissue engineering and regenerative medicine 20101001
Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS. Fitoterapia 20100901
Role and mechanism of uncoupling protein 2 on the fatty acid-induced dysfunction of pancreatic alpha cells in vitro. Chinese medical journal 20100901
Concise synthesis of 5,6-dihydrovaltrate leading to enhanced Rev-export inhibitory congener. Bioorganic & medicinal chemistry 20100815
Antidepressant-like effect of genipin in mice. Neuroscience letters 20100802
Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia. The Biochemical journal 20100715
Genipin protects lipopolysaccharide-induced apoptotic liver damage in D-galactosamine-sensitized mice. European journal of pharmacology 20100610
Assessment of biocompatibility and initial evaluation of genipin cross-linked elastin-like polypeptides in the treatment of an osteochondral knee defect in rabbits. Acta biomaterialia 20100601
Investigation on magnetically controlled delivery of doxorubicin from superparamagnetic nanocarriers of gelatin crosslinked with genipin. Journal of materials science. Materials in medicine 20100501
Effect of genipin on cholestasis induced by estradiol-17beta-glucuronide and lithocholate-3-O-glucuornide in rats. Hepatology research : the official journal of the Japan Society of Hepatology 20100501
Urinary biomarkers trefoil factor 3 and albumin enable early detection of kidney tubular injury. Nature biotechnology 20100501
Effects of enzymatic digestion on compressive properties of rat intervertebral discs. Journal of biomechanics 20100419
Evaluation of composition and crosslinking effects on collagen-based composite constructs. Acta biomaterialia 20100401
Novel pH-sensitive chitosan-based hydrogel for encapsulating poorly water-soluble drugs. Acta biomaterialia 20100401
Kinetic characterization and comparison of various protein crosslinking reagents for matrix modification. Journal of materials science. Materials in medicine 20100401
Genipin inhibits the inflammatory response of rat brain microglial cells. International immunopharmacology 20100401
Inchinkoto, an herbal medicine, exerts beneficial effects in the rat liver under stress with hepatic ischemia-reperfusion and subsequent hepatectomy. Annals of surgery 20100401
Effect of genipin collagen crosslinking on porcine corneas. Journal of cataract and refractive surgery 20100401
Biocompatibility of nanostructured chitosan/ poly(vinyl alcohol) blends chemically crosslinked with genipin for biomedical applications. Journal of biomedical nanotechnology 20100401
Combined NMR and LC-MS analysis reveals the metabonomic changes in Salvia miltiorrhiza Bunge induced by water depletion. Journal of proteome research 20100305
Uncoupling protein-2 modulates myocardial excitation-contraction coupling. Circulation research 20100305
Inhibitory Potencies of Several Iridoids on Cyclooxygenase-1, Cyclooxygnase-2 Enzymes Activities, Tumor Necrosis factor-α and Nitric Oxide Production In Vitro. Evidence-based complementary and alternative medicine : eCAM 20100301
Novel multiarm PEG-based hydrogels for tissue engineering. Journal of biomedical materials research. Part A 20100301
Physicochemical and biological activity study of genipin-crosslinked chitosan scaffolds prepared by using supercritical carbon dioxide for tissue engineering applications. International journal of biological macromolecules 20100301
Active ingredients of traditional Japanese (kampo) medicine, inchinkoto, in murine concanavalin A-induced hepatitis. Journal of ethnopharmacology 20100217
Effect of adipic dihydrazide modification on the performance of collagen/hyaluronic acid scaffold. Journal of biomedical materials research. Part B, Applied biomaterials 20100201
In vitro study in the endothelial cell compatibility and endothelialization of genipin-crosslinked biological tissues for tissue-engineered vascular scaffolds. Journal of materials science. Materials in medicine 20100201
Neuritogenic activities of 1-alkyloxygenipins. Chemical & pharmaceutical bulletin 20100201
The development of genipin-crosslinked poly(caprolactone) (PCL)/gelatin nanofibers for tissue engineering applications. Macromolecular bioscience 20100111
Exogenous crosslinking recovers the functional integrity of intervertebral disc secondary to a stab injury. Journal of biomedical materials research. Part A 20100101
Microencapsulation of isoniazid in genipin-crosslinked gelatin-A-κ-carrageenan polyelectrolyte complex. Drug development and industrial pharmacy 20100101
Microencapsulation in genipin cross-linked gelatine-maltodextrin improves survival of Bifidobacterium adolescentis during exposure to in vitro gastrointestinal conditions. Journal of microencapsulation 20100101
Glucose sensing in the pancreatic beta cell: a computational systems analysis. Theoretical biology & medical modelling 20100101
Composite films of gelatin and hydroxyapatite/bioactive glass for tissue-engineering applications. Journal of biomaterials science. Polymer edition 20100101
Chitosan-genipin microspheres for the controlled release of drugs: clarithromycin, tramadol and heparin. Marine drugs 20100101
Genipin induced apoptosis associated with activation of the c-Jun NH2-terminal kinase and p53 protein in HeLa cells. Biological & pharmaceutical bulletin 20100101
Catalpol increases brain angiogenesis and up-regulates VEGF and EPO in the rat after permanent middle cerebral artery occlusion. International journal of biological sciences 20100101
Marine polysaccharides in pharmaceutical applications: an overview. Marine drugs 20100101
Genipin-induced inhibition of uncoupling protein-2 sensitizes drug-resistant cancer cells to cytotoxic agents. PloS one 20100101
In vitro response of retinal pigment epithelial cells exposed to chitosan materials prepared with different cross-linkers. International journal of molecular sciences 20100101
Genipin enhances the mechanical properties of tissue-engineered cartilage and protects against inflammatory degradation when used as a medium supplement. Journal of biomedical materials research. Part A 20091201
Highly permeable genipin-cross-linked gelatin conduits enhance peripheral nerve regeneration. Artificial organs 20091201
Differentiation of bone marrow stromal cells in poly(lactide-co-glycolide)/chitosan scaffolds. Biomaterials 20091201
Lamiridosins, hepatitis C virus entry inhibitors from Lamium album. Journal of natural products 20091201
Preparation, characterization, and pharmacokinetics of the inclusion complex of genipin-beta-cyclodextrin. Drug development and industrial pharmacy 20091201
Effects of nerve growth factor from genipin-crosslinked gelatin in polycaprolactone conduit on peripheral nerve regeneration--in vitro and in vivo. Journal of biomedical materials research. Part A 20091101
A novel injectable hydrogel in combination with a surgical sealant in a rat knee osteochondral defect model. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 20091101
The detection of latent fingermarks on porous surfaces using amino acid sensitive reagents: a review. Analytica chimica acta 20091012
The use of collagen cross-linking agents to enhance dentin bond strength. Journal of biomedical materials research. Part B, Applied biomaterials 20091001
Mechanical properties, drug eluting characteristics and in vivo performance of a genipin-crosslinked chitosan polymeric stent. Biomaterials 20091001
Targeted expression of uncoupling protein 2 to mouse liver increases the susceptibility to lipopolysaccharide/galactosamine-induced acute liver injury. Hepatology (Baltimore, Md.) 20091001
The effect of hydrolyzed gardeniae fructus extract hydrogel on the treatment of ecchymoses in a rat model. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20091001
Regulating fibrinolysis to engineer skeletal muscle from the C2C12 cell line. Tissue engineering. Part C, Methods 20090901
Effect of genipin cross-linking on the cellular adhesion properties of layer-by-layer assembled polyelectrolyte films. Biomaterials 20090901
Evaluation of cross-linking methods for electrospun gelatin on cell growth and viability. Biomacromolecules 20090713
Microfluidic controlling monodisperse microdroplet for 5-fluorouracil loaded genipin-gelatin microcapsules. Journal of controlled release : official journal of the Controlled Release Society 20090701
Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes 20090701
Neuroprotective action of genipin on tunicamycin-induced cytotoxicity in neuro2a cells. Biological & pharmaceutical bulletin 20090701
Isolation of antifungal compounds from Gardenia jasminoides. Pakistan journal of biological sciences : PJBS 20090701
Asymmetric chitosan membrane containing collagen I nanospheres for skin tissue engineering. Biomacromolecules 20090608
Nuclear factor-kappaB bioluminescence imaging-guided transcriptomic analysis for the assessment of host-biomaterial interaction in vivo. Biomaterials 20090601
Inhibition of uncoupling protein 2 by genipin reduces insulin-stimulated glucose uptake in 3T3-L1 adipocytes. Archives of biochemistry and biophysics 20090601
Gardenia jasminoides Ellis ethanol extract and its constituents reduce the risks of gastritis and reverse gastric lesions in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090601
Genipin suppresses A23187-induced cytotoxicity in neuro2a cells. Biological & pharmaceutical bulletin 20090601
Genipin-crosslinked casein hydrogels for controlled drug delivery. International journal of pharmaceutics 20090521
Genipin inhibits endothelial exocytosis via nitric oxide in cultured human umbilical vein endothelial cells. Acta pharmacologica Sinica 20090501
Creation of macroporous calcium phosphate cements as bone substitutes by using genipin-crosslinked gelatin microspheres. Journal of materials science. Materials in medicine 20090401
Iridoid glycosides from Gardeniae Fructus for treatment of ankle sprain. Phytochemistry 20090401
[Characterization and biocompatibility of human-like collagen-hyaluronic acid scaffold for blood vessel]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20090401
Rheological, microstructural, and in vitro characterization of hybrid chitosan-polylactic acid/hydroxyapatite composites. Journal of biomedical materials research. Part A 20090315
The effect of pulse-released nerve growth factor from genipin-crosslinked gelatin in schwann cell-seeded polycaprolactone conduits on large-gap peripheral nerve regeneration. Tissue engineering. Part A 20090301
Neurite growth in 3D collagen gels with gradients of mechanical properties. Biotechnology and bioengineering 20090201
Porous composite scaffolds based on gelatin and partially hydrolyzed alpha-tricalcium phosphate. Acta biomaterialia 20090201
Type II collagen-chondroitin sulfate-hyaluronan scaffold cross-linked by genipin for cartilage tissue engineering. Journal of bioscience and bioengineering 20090201
[Comparison of characteristics between glutaraldehyde- and genipin-crosslinked gelatin microspheres]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20090101
Genipin cross-linked fibrin hydrogels for in vitro human articular cartilage tissue-engineered regeneration. Cells, tissues, organs 20090101
Collagen matrices from sponge to nano: new perspectives for tissue engineering of skeletal muscle. BMC biotechnology 20090101
In-chern-hau-tang and genipin reduces acute urinary bladder distension evoked sympathetic activation-induced hepatic dysfunction in rats. The American journal of Chinese medicine 20090101
Chinese medicines as a resource for liver fibrosis treatment. Chinese medicine 20090101
[Effect of UCP2 activity inhibitor genipin on heart function of aging rats]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101
[Effects of uncoupling proteins on nitric oxide synthesis and oxidative stress development in ishemia-reperfusion of old rat hearts]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101
Comparative performance of electrospun collagen nanofibers cross-linked by means of different methods. ACS applied materials & interfaces 20090101
Cross-linking methods of electrospun fibrinogen scaffolds for tissue engineering applications. Biomedical materials (Bristol, England) 20081201
Using orthogonal array to obtain gradient liquid chromatography conditions of enhanced peak intensity to determine geniposide and genipin with electrospray tandem mass spectrometry. Journal of chromatography. A 20081128
Genipin-induced changes in collagen gels: correlation of mechanical properties to fluorescence. Journal of biomedical materials research. Part A 20081101
pH-sensitive genipin-cross-linked chitosan microspheres for heparin removal. Biomacromolecules 20081101
Genipin blues: an alternative non-toxic crosslinker for heart valves? The Journal of heart valve disease 20081101
Nanocomposites of genipin-crosslinked chitosan/silver nanoparticles--structural reinforcement and antimicrobial properties. Macromolecular bioscience 20081008
Novel genipin-cross-linked chitosan/silk fibroin sponges for cartilage engineering strategies. Biomacromolecules 20081001
Preparation of genipin cross-linked chitosan-gelatin microcapsules for encapsulation of Zanthoxylum limonella oil (ZLO) using salting-out method. Journal of microencapsulation 20080901
Colon-targeted delivery of live bacterial cell biotherapeutics including microencapsulated live bacterial cells. Biologics : targets & therapy 20080901
Genipin-modified silk-fibroin nanometric nets. Macromolecular bioscience 20080811
Effects of natural cross-linkers on the stability of dentin collagen and the inhibition of root caries in vitro. Caries research 20080801
Metabolism and pharmacokinetics of genipin and geniposide in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080801
Chitosan microparticles as injectable scaffolds for tissue engineering. Journal of tissue engineering and regenerative medicine 20080801
Crosslinking of an oesophagus acellular matrix tissue scaffold. Journal of tissue engineering and regenerative medicine 20080801
Simultaneous determination of geniposide and its metabolites genipin and genipinine in culture of Aspergillus niger by HPLC. Biomedical chromatography : BMC 20080701
Effect of genipin on the biliary excretion of cholephilic compounds in rats. Hepatology research : the official journal of the Japan Society of Hepatology 20080601
Biotransformation of ginsenoside Rb1, crocin, amygdalin, geniposide, puerarin, ginsenoside Re, hesperidin, poncirin, glycyrrhizin, and baicalin by human fecal microflora and its relation to cytotoxicity against tumor cells. Journal of microbiology and biotechnology 20080601
Evaluation of a non-woven fabric coated with a chitosan bi-layer composite for wound dressing. Macromolecular bioscience 20080513
Genipin exhibits neurotrophic effects through a common signaling pathway in nitric oxide synthase-expressing cells. European journal of pharmacology 20080310
Evaluation of the release rate of bioactive recombinant human epidermal growth factor from crosslinking collagen sponges. Journal of materials science. Materials in medicine 20080301
Genipin-crosslinked chitosan/gelatin blends for biomedical applications. Journal of materials science. Materials in medicine 20080201
[Study on the temporal change of properties of genipin crosslinked gelatin]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20080201
Effects of collagen crosslinking on tissue fragility. Clinical biomechanics (Bristol, Avon) 20080101
[The role of mitochondrial uncoupling proteins in the development of changes of endothelium-dependent reactions of the heart and vessels in experimental diabetes mellitus]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101
Controlled release of DSBP from genipin-crosslinked gelatin thin films. Pharmaceutical development and technology 20080101
Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion. PloS one 20080101
The Potential of N-Rich Plasma-Polymerized Ethylene (PPE:N) Films for Regulating the Phenotype of the Nucleus Pulposus. The open orthopaedics journal 20080101
Immobilization of drugs for glaucoma treatment. Journal of materials science. Materials in medicine 20071201
A fibrinogen-based precision microporous scaffold for tissue engineering. Biomaterials 20071201
Rheological study of genipin cross-linked chitosan hydrogels. Biomacromolecules 20071201
Molecularly imprinted chitosan-genipin hydrogels with recognition capacity toward o-xylene. Biomacromolecules 20071101
Synthesis of monoterpene alkaloid derivatives from the iridoid glucoside geniposide. Natural product research 20071101
Mixed lineage kinase 3 connects reactive oxygen species to c-Jun NH2-terminal kinase-induced mitochondrial apoptosis in genipin-treated PC3 human prostate cancer cells. Biochemical and biophysical research communications 20071019
Noninvasive nuclear factor-kappaB bioluminescence imaging for the assessment of host-biomaterial interaction in transgenic mice. Biomaterials 20071001
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity. Nature 20070913
Gelatin microspheres encapsulated with a nonpeptide angiogenic agent, ginsenoside Rg1, for intramyocardial injection in a rat model with infarcted myocardium. Journal of controlled release : official journal of the Controlled Release Society 20070716
Preparation and evaluation of ketorolac tromethamine gel containing genipin for periodontal diseases. Archives of pharmacal research 20070701
Effect of gelatin on the drug release behaviors for the organic hybrid gels based on N-isopropylacrylamide and gelatin. Journal of materials science. Materials in medicine 20070601
Effect of genipin, a naturally occurring crosslinker on the properties of kappa-carrageenan. International journal of biological macromolecules 20070601
Inchinkoto, a herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers. American journal of physiology. Gastrointestinal and liver physiology 20070501
Density quantification of collagen grafted on biodegradable polyester: its application to esophageal smooth muscle cell. Analytical biochemistry 20070401
Fingerprint reagents with dual action: color and fluorescence. Journal of forensic sciences 20070301
Effect of process variables on particle size and viability of Bifidobacterium lactis Bb-12 in genipin-gelatin microspheres. Journal of microencapsulation 20070301
Microstructural and tensile properties of elastin-based polypeptides crosslinked with genipin and pyrroloquinoline quinone. Biopolymers 20070215
Constituents of Gardenia volkensii: their brine shrimp lethality and DPPH radical scavenging properties. Natural product research 20070201
The effect of nucleus pulposus crosslinking and glycosaminoglycan degradation on disc mechanical function. Biomechanics and modeling in mechanobiology 20070101
Application of crosslinkers to dentin collagen enhances the ultimate tensile strength. Journal of biomedical materials research. Part B, Applied biomaterials 20070101
In vitro and in vivo tissue repair with laser-activated chitosan adhesive. Lasers in surgery and medicine 20070101
Preparation and characterization of novel polymeric microcapsules for live cell encapsulation and therapy. Cell biochemistry and biophysics 20070101
Bonding of articular cartilage using a combination of biochemical degradation and surface cross-linking. Arthritis research & therapy 20070101
Immobilization of lipase to chitosan beads using a natural cross-linker. Preparative biochemistry & biotechnology 20070101
Influence of cross-linking degree of a biodegradable genipin-cross-linked gelatin guide on peripheral nerve regeneration. Journal of biomaterials science. Polymer edition 20070101
The effect of novel nitrogen-rich plasma polymer coatings on the phenotypic profile of notochordal cells. Biomedical engineering online 20070101
Kinetic and mechanistic considerations in the gelation of genipin-crosslinked gelatin. International journal of biological macromolecules 20061115
Swelling and mechanical properties of biopolymer hydrogels containing chitosan and bovine serum albumin. Biomacromolecules 20061101
Genipin suppression of fibrogenic behaviors of the alpha-TN4 lens epithelial cell line. Journal of cataract and refractive surgery 20061001
Effect of genipin-crosslinked chitin-chitosan scaffolds with hydroxyapatite modifications on the cultivation of bovine knee chondrocytes. Biotechnology and bioengineering 20060905
A new method for microcapsule characterization: use of fluorogenic genipin to characterize polymeric microcapsule membranes. Applied biochemistry and biotechnology 20060901
Controlled in vivo degradation of genipin crosslinked polyethylene glycol hydrogels within osteochondral defects. Tissue engineering 20060901
Exogenous cross-linking increases the stability of spinal motion segments. Spine 20060701
Genipin cross-linked alginate-chitosan microcapsules: membrane characterization and optimization of cross-linking reaction. Biomacromolecules 20060701
Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets. Cell metabolism 20060601
Controlled release of bioactive TGF-beta 1 from microspheres embedded within biodegradable hydrogels. Biomaterials 20060301
Some physical and microstructural properties of genipin-crosslinked gelatin-maltodextrin hydrogels. International journal of biological macromolecules 20060227
Anti-inflammatory evaluation of gardenia extract, geniposide and genipin. Journal of ethnopharmacology 20060220
Differences in neuritogenic response to nitric oxide in PC12 and PC12h cells. Neuroscience letters 20060130
The potential of chitosan-based gels containing intervertebral disc cells for nucleus pulposus supplementation. Biomaterials 20060101
Genipin suppresses subconjunctival fibroblast migration, proliferation and myofibroblast transdifferentiation. Ophthalmic research 20060101
Characterizing poly(epsilon-caprolactone)-b-chitooligosaccharide-b-poly(ethylene glycol) (PCP) copolymer micelles for doxorubicin (DOX) delivery: effects of crosslinked of amine groups. Journal of nanoscience and nanotechnology 20060101
Reaction of chitosan with genipin and its fluorogenic attributes for potential microcapsule membrane characterization. Journal of biomedical materials research. Part A 20051215
Genipin prevents fulminant hepatic failure resulting in reduction of lethality through the suppression of TNF-alpha production. Hepatology research : the official journal of the Japan Society of Hepatology 20051201
Cell-free xenogenic vascular grafts fixed with glutaraldehyde or genipin: in vitro and in vivo studies. Journal of biotechnology 20051104
A novel drug-eluting stent spray-coated with multi-layers of collagen and sirolimus. Journal of controlled release : official journal of the Controlled Release Society 20051102
Genipin-induced apoptosis in hepatoma cells is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of mitochondrial pathway. Biochemical pharmacology 20051101
Genipin, a novel fingerprint reagent with colorimetric and fluorogenic activity, part II: optimization, scope and limitations. Journal of forensic sciences 20051101
Tissue regeneration observed in a porous acellular bovine pericardium used to repair a myocardial defect in the right ventricle of a rat model. The Journal of thoracic and cardiovascular surgery 20050901
Peritoneal regeneration induced by an acellular bovine pericardial patch in the repair of abdominal wall defects. The Journal of surgical research 20050801
Calvarial bone response to a tricalcium phosphate-genipin crosslinked gelatin composite. Biomaterials 20050601
An in vivo evaluation of a biodegradable genipin-cross-linked gelatin peripheral nerve guide conduit material. Biomaterials 20050601
Structural changes in pericardium tissue modified with tannic acid. The International journal of artificial organs 20050601
Construction of varying porous structures in acellular bovine pericardia as a tissue-engineering extracellular matrix. Biomaterials 20050501
PEG-grafted chitosan as an injectable thermosensitive hydrogel for sustained protein release. Journal of controlled release : official journal of the Controlled Release Society 20050418
A natural compound (ginsenoside Re) isolated from Panax ginseng as a novel angiogenic agent for tissue regeneration. Pharmaceutical research 20050401
Biological evaluation of chitosan salts cross-linked to genipin as a cell scaffold for disk tissue engineering. Tissue engineering 20050101
Synthesis and characterization of a novel chitosan-gelatin bioconjugate with fluorescence emission. Biomacromolecules 20050101
pH-sensitive behavior of two-component hydrogels composed of N,O-carboxymethyl chitosan and alginate. Journal of biomaterials science. Polymer edition 20050101
Biodegradable poly(ethylene glycol) hydrogels crosslinked with genipin for tissue engineering applications. Journal of biomedical materials research. Part B, Applied biomaterials 20041015
Japanese herbal medicine Inchin-ko-to as a therapeutic drug for liver fibrosis. Journal of hepatology 20041001
Metabolic activities of ginsenoside Rb1, baicalin, glycyrrhizin and geniposide to their bioactive compounds by human intestinal microflora. Biological & pharmaceutical bulletin 20041001
Effects of crosslinking degree of an acellular biological tissue on its tissue regeneration pattern. Biomaterials 20040801
Antiinflammatory effects of genipin, an active principle of gardenia. European journal of pharmacology 20040714
A novel use of genipin-fixed gelatin as extracellular matrix for peripheral nerve regeneration. Journal of biomaterials applications 20040701
Biocompatibility and biodegradation of a bone composite containing tricalcium phosphate and genipin crosslinked gelatin. Journal of biomedical materials research. Part A 20040615
[Methods for the pre-treatment of biological tissues for vascular scaffold]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20040601
Tissue regeneration patterns in acellular bovine pericardia implanted in a canine model as a vascular patch. Journal of biomedical materials research. Part A 20040501
Hemoglobin polymerized with a naturally occurring crosslinking agent as a blood substitute: in vitro and in vivo studies. Artificial cells, blood substitutes, and immobilization biotechnology 20040501
A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery. Journal of controlled release : official journal of the Controlled Release Society 20040428
Cyclic GMP-dependent neurite outgrowth by genipin and nerve growth factor in PC12h cells. European journal of pharmacology 20040319
Genipin--a novel fingerprint reagent with colorimetric and fluorogenic activity. Journal of forensic sciences 20040301
Novel chitosan-based films cross-linked by genipin with improved physical properties. Biomacromolecules 20040101
Genipin enhances Mrp2 (Abcc2)-mediated bile formation and organic anion transport in rat liver. Hepatology (Baltimore, Md.) 20040101
Acellular bovine pericardia with distinct porous structures fixed with genipin as an extracellular matrix. Tissue engineering 20040101
Albumin-genipin solder for laser tissue repair. Lasers in surgery and medicine 20040101
In vitro evaluation of degradation and cytotoxicity of a novel composite as a bone substitute. Journal of biomedical materials research. Part A 20031215
Genipin-crosslinked gelatin microspheres as a drug carrier for intramuscular administration: in vitro and in vivo studies. Journal of biomedical materials research. Part A 20030501
Crosslinking of biological tissues using genipin and/or carbodiimide. Journal of biomedical materials research. Part A 20030301
Complement-inhibiting iridoids from Morinda morindoides. Journal of natural products 20030101
A genipin-crosslinked gelatin membrane as wound-dressing material: in vitro and in vivo studies. Journal of biomaterials science. Polymer edition 20030101
Stabilization of gelatin films by crosslinking with genipin. Biomaterials 20021201
Genotoxicity of gardenia yellow and its components. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021101
Isolation and characterization of water-soluble intermediates of blue pigments transformed from geniposide of Gardenia jasminoides. Journal of agricultural and food chemistry 20021023
[Studies on the cytological function of the biomembrane and the neurons]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20021001
In vivo evaluation of cellular and acellular bovine pericardia fixed with a naturally occurring crosslinking agent (genipin). Biomaterials 20020601
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
In vivo biocompatibility and degradability of a novel injectable-chitosan-based implant. Biomaterials 20020101
Reconstruction of the right ventricular outflow tract with a bovine jugular vein graft fixed with a naturally occurring crosslinking agent (genipin) in a canine model. The Journal of thoracic and cardiovascular surgery 20011201
Antithrombotic effect of geniposide and genipin in the mouse thrombosis model. Planta medica 20011201
Prevention of the neurotoxicity of the amyloid beta protein by genipin. Biological & pharmaceutical bulletin 20011201
Activation of the mitogen-activated protein kinase cascade through nitric oxide synthesis as a mechanism of neuritogenic effect of genipin in PC12h cells. Journal of neurochemistry 20011001
Simultaneous estimation of geniposide and genipin in mouse plasma using high-performance liquid chromatography. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20011001
Stability of a biological tissue fixed with a naturally occurring crosslinking agent (genipin). Journal of biomedical materials research 20010615
Effects of heparin immobilization on the surface characteristics of a biological tissue fixed with a naturally occurring crosslinking agent (genipin): an in vitro study. Biomaterials 20010301
Physical stability of the blue pigments formed from geniposide of gardenia fruits: effects of pH, temperature, and light. Journal of agricultural and food chemistry 20010101
Harvested porcine mitral xenograft fixation: impact on fluid dynamic performance. The Journal of heart valve disease 20010101
In vitro evaluation of a chitosan membrane cross-linked with genipin. Journal of biomaterials science. Polymer edition 20010101
Properties