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Aranidipine

CAS No.:
86780-90-7
Catalog Number:
AG00GRKP
Molecular Formula:
C19H20N2O7
Molecular Weight:
388.3713
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$140
- +
10mg
99%
1 week
United States
$203
- +
50mg
99%
1 week
United States
$494
- +
100mg
99%
1 week
United States
$800
- +
Product Description
Catalog Number:
AG00GRKP
Chemical Name:
Aranidipine
CAS Number:
86780-90-7
Molecular Formula:
C19H20N2O7
Molecular Weight:
388.3713
MDL Number:
MFCD00865813
IUPAC Name:
3-O-methyl 5-O-(2-oxopropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
InChI:
InChI=1S/C19H20N2O7/c1-10(22)9-28-19(24)16-12(3)20-11(2)15(18(23)27-4)17(16)13-7-5-6-8-14(13)21(25)26/h5-8,17,20H,9H2,1-4H3
InChI Key:
NCUCGYYHUFIYNU-UHFFFAOYSA-N
SMILES:
COC(=O)C1=C(C)NC(=C(C1c1ccccc1[N+](=O)[O-])C(=O)OCC(=O)C)C
Properties
Complexity:
748  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
388.127g/mol
Formal Charge:
0
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
388.376g/mol
Monoisotopic Mass:
388.127g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
128A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
2  
Literature
Title Journal
Efficacy and safety of aranidipine enteric-coated tablets compared with amlodipine in Chinese patients with mild to moderate essential hypertension: a multicenter, randomized, double-blind, parallel-controlled clinical trial. Journal of cardiovascular pharmacology 20120701
Pharmacokinetic and pharmacodynamic characteristics of aranidipine sustained-release, enteric-coated tablets in healthy Chinese men: a phase I, randomized, open-label, single- and multiple-dose study. Clinical therapeutics 20080701
Determination of aranidipine and its active metabolite in human plasma by liquid chromatography/negative electrospray ionization tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20060101
Divergent action of calcium channel blockers on ATP-binding cassette protein expression. Journal of cardiovascular pharmacology 20051201
Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: prediction of in vivo drug-drug interactions. European journal of clinical pharmacology 20000101
Regional vascular effects of MPC-1304, a novel dihydropyridine derivative, in conscious normotensive and spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics 19960601
Properties