(2R,3S,4S,5R)-2-(2-amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
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Nelarabine neurotoxicity with concurrent intrathecal chemotherapy: Case report and review of literature. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20150801 |
Pilot study of nelarabine in combination with intensive chemotherapy in high-risk T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120801 |
Novel and emerging drugs for rarer chronic lymphoid leukaemias. | Current cancer drug targets 20120601 |
Treatment of acute lymphoblastic leukemia in adults. | Critical reviews in oncology/hematology 20120101 |
Emerging pharmacotherapies for adult patients with acute lymphoblastic leukemia. | Clinical Medicine Insights. Oncology 20120101 |
Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. | Current pharmaceutical design 20120101 |
Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism. | PloS one 20120101 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
High single-drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation. | Blood 20110929 |
Precursor T-Cell acute lymphoblastic leukemia/lymphoma with rare presentation in the urinary bladder. | Hematology reports 20110831 |
In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia. | Blood 20110825 |
[Novel conventional therapies in onco-hemathology]. | Bulletin du cancer 20110801 |
Phase I study of nelarabine in patients with relapsed or refractory T-ALL/T-LBL. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20110601 |
Educational paper. The development of new therapies for pediatric oncology. | European journal of pediatrics 20110501 |
Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway. | European journal of nuclear medicine and molecular imaging 20110401 |
New nucleoside analogs for patients with hematological malignancies. | Expert opinion on investigational drugs 20110301 |
A Systematic Review and Meta-Analysis of Front-line Anthracycline-Based Chemotherapy Regimens for Peripheral T-Cell Lymphoma. | ISRN hematology 20110101 |
Molecular diagnostics, targeted therapy, and the indication for allogeneic stem cell transplantation in acute lymphoblastic leukemia. | Advances in hematology 20110101 |
An update on the management of peripheral T-cell lymphoma and emerging treatment options. | Journal of blood medicine 20110101 |
Rare tumors research in emerging countries. | Rare tumors 20100930 |
Towards the development of a rapid, portable, surface enhanced Raman spectroscopy based cleaning verification system for the drug nelarabine. | The Journal of pharmacy and pharmacology 20100901 |
Salvage therapy with nelarabine, etoposide, and cyclophosphamide in relapsed/refractory paediatric T-cell lymphoblastic leukaemia and lymphoma. | British journal of haematology 20100801 |
Complete paraplegia after nelarabine treatment in a T-cell acute lymphoblastic leukemia adult patient. | American journal of hematology 20100801 |
New trends in nucleoside biotechnology. | Acta naturae 20100701 |
A new high-performance liquid chromatography method determines low production of 9-beta-D-arabinofuranosylguanine triphosphate, an active metabolite of nelarabine, in adult T-cell leukemia cells. | Oncology reports 20100201 |
Risk sharing arrangements for pharmaceuticals: potential considerations and recommendations for European payers. | BMC health services research 20100101 |
Use of clofarabine for acute childhood leukemia. | Biologics : targets & therapy 20100101 |
Hydronephrosis Resulting from Bilateral Ureteral Stenosis: A Late Complication of Polyoma BK Virus Cystitis? | Journal of transplantation 20100101 |
Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia. | Molecular cancer 20100101 |
Nelarabine in the treatment of refractory T-cell malignancies. | Clinical Medicine Insights. Oncology 20100101 |
Application of new drugs in chronic lymphocytic leukemia. | Mediterranean journal of hematology and infectious diseases 20100101 |
T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993). | Blood 20091210 |
Nelarabine for the treatment of patients with relapsed or refractory T-cell acute lymphoblastic leukemia or lymphoblastic lymphoma. | Hematology/oncology clinics of North America 20091001 |
Nelarabine induced complete remission in an adult with refractory T-lineage acute lymphoblastic leukemia: A case report and review of the literature. | Leukemia research 20090701 |
Novel therapies for relapsed acute lymphoblastic leukemia. | Current hematologic malignancy reports 20090701 |
Glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia is associated with a proliferative metabolism. | British journal of cancer 20090616 |
Current status of older and new purine nucleoside analogues in the treatment of lymphoproliferative diseases. | Molecules (Basel, Switzerland) 20090323 |
Nelarabine: new drug. T-lymphoblastic leukaemia/lymphoma: more evaluation needed. | Prescrire international 20090201 |
[Severe liver injury following nelarabine chemotherapy for T-cell lymphoblastic lymphoma]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20090101 |
Development of fludarabine formulations in the treatment of chronic lymphocytic leukemia. | Drug design, development and therapy 20090101 |
Profile of nelarabine: use in the treatment of T-cell acute lymphoblastic leukemia. | OncoTargets and therapy 20090101 |
Novel purine nucleoside analogues for hematological malignancies. | Recent patents on anti-cancer drug discovery 20080601 |
FDA drug approval summary: nelarabine (Arranon) for the treatment of T-cell lymphoblastic leukemia/lymphoma. | The oncologist 20080601 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20080501 |
Beyond the guidelines in the treatment of peripheral T-cell lymphoma: new drug development. | Journal of the National Comprehensive Cancer Network : JNCCN 20080401 |
Treating refractory leukemias in childhood, role of clofarabine. | Therapeutics and clinical risk management 20080401 |
Phase I trial of nelarabine in indolent leukemias. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080301 |
Nelarabine. | Drugs 20080101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20080101 |
Cytotoxic nucleoside analogues: different strategies to improve their clinical efficacy. | Current medicinal chemistry 20080101 |
Three new drugs for acute lymphoblastic leukemia: nelarabine, clofarabine, and forodesine. | Seminars in oncology 20071201 |
Clinical management of T-cell malignancies: current perspectives, key issues, and emerging therapies. | Seminars in oncology 20071201 |
Role of nelarabine in the treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. | Therapeutics and clinical risk management 20071201 |
Nelarabine activity in acute biphenotypic leukemia. | Leukemia research 20071101 |
Nelarabine: a novel purine antimetabolite antineoplastic agent. | Clinical therapeutics 20070901 |
Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801. | Blood 20070615 |
Plasma and cerebrospinal fluid pharmacokinetics of nelarabine in nonhuman primates. | Cancer chemotherapy and pharmacology 20070501 |
In vitro cytotoxicity of nelarabine, clofarabine and flavopiridol in paediatric acute lymphoblastic leukaemia. | British journal of haematology 20070401 |
New drugs 07, part I. | Nursing 20070201 |
The long and winding road of the clinical development of Nelarabine. | Leukemia & lymphoma 20070101 |
Results of a phase II study of 506U78 in cutaneous T-cell lymphoma and peripheral T-cell lymphoma: CALGB 59901. | Leukemia & lymphoma 20070101 |
Treatment of acute lymphoblastic leukaemia : a new era. | Drugs 20070101 |
Novel purine nucleoside analogues for T-cell-lineage acute lymphoblastic leukaemia and lymphoma. | Expert opinion on investigational drugs 20061201 |
Efficacy of low dose clofarabine in refractory precursor T- acute lymphoblastic leukemia. | The Yale journal of biology and medicine 20061201 |
Clofarabine and nelarabine: two new purine nucleoside analogs. | Current opinion in oncology 20061101 |
Milestones in oncology: introducing a new section. | The oncologist 20061001 |
The legacy of great science: the work of Nobel Laureate Gertrude Elion lives on. | The oncologist 20061001 |
[Glaxo Smith Kline. A large oncology pipeline]. | Medizinische Monatsschrift fur Pharmazeuten 20061001 |
Approval summary: nelarabine for the treatment of T-cell lymphoblastic leukemia/lymphoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060915 |
Nelarabine in the treatment of refractory T-cell malignant diseases. | Expert opinion on pharmacotherapy 20060901 |
Nelarabine: a new purine analog in the treatment of hematologic malignancies. | Reviews on recent clinical trials 20060901 |
Nelarabine: efficacy in the treatment of clinical malignancies. | Future oncology (London, England) 20060801 |
Multifocal necrotizing leukoencephalopathy: An unusual complication of acute leukemia. | Archives of neurology 20060701 |
Nelarabine use in leukemias. | Drugs of today (Barcelona, Spain : 1998) 20060701 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060601 |
Pharmacological and clinical studies on purine nucleoside analogs--new anticancer agents. | Mini reviews in medicinal chemistry 20060501 |
Nelarabine (Arranon) for T-cell acute lymphoblastic leukemia. | The Medical letter on drugs and therapeutics 20060213 |
Nelarabine. | Nature reviews. Drug discovery 20060101 |
New drug to treat rare leukemia and lymphoma. | FDA consumer 20060101 |
New drugs: abatacept, sorafenib, and nelarabine. | Journal of the American Pharmacists Association : JAPhA 20060101 |
Purine nucleoside analogs as immunosuppressive and antineoplastic agents: mechanism of action and clinical activity. | Current medicinal chemistry 20060101 |
Purine nucleoside analogues for the treatment of hematological malignancies: pharmacology and clinical applications. | Current cancer drug targets 20050901 |
Nelarabine: a nucleoside analog with efficacy in T-cell and other leukemias. | The Annals of pharmacotherapy 20050601 |
Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: a report from the Children's Oncology Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050520 |
Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050520 |
Purine nucleoside antimetabolites in development for the treatment of cancer. | Current opinion in investigational drugs (London, England : 2000) 20040601 |
New nucleoside analogs in the treatment of hematological disorders. | Acta poloniae pharmaceutica 20040101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20031101 |
Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. | Cancer research 20020601 |
CD4-CD8-'Double-negative' cutaneous T-cell lymphomas share common histologic features and an aggressive clinical course. | The American journal of surgical pathology 20020201 |
Nitric oxide enhancement of fludarabine cytotoxicity for B-CLL lymphocytes. | Leukemia 20011201 |
Nucleoside analogues in the treatment of haematological malignancies. | Expert opinion on pharmacotherapy 20010601 |
Evaluation of the combination of nelarabine and fludarabine in leukemias: clinical response, pharmacokinetics, and pharmacodynamics in leukemia cells. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010415 |
6-Methoxypurine arabinoside as a selective and potent inhibitor of varicella-zoster virus. | Antimicrobial agents and chemotherapy 19910501 |