Aspidospermidine-3-carboxylic acid,4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-, methylester, (2b,3b,4b,5a,12R,19a)-
| Title | Journal |
|---|---|
| Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast. | Proceedings of the National Academy of Sciences of the United States of America 20150512 |
| Increased availability of tryptophan in 5-methyltryptophan-tolerant shoots of Catharanthus roseus and their postharvest in vivo elicitation induces enhanced vindoline production. | Applied biochemistry and biotechnology 20121001 |
| Negative-pressure cavitation extraction of four main vinca alkaloids from Catharanthus roseus leaves. | Molecules (Basel, Switzerland) 20120725 |
| Modifications on the basic skeletons of vinblastine and vincristine. | Molecules (Basel, Switzerland) 20120518 |
| The effect of vindoline C-16 substituents on the biomimetic coupling reaction: synthesis and cytotoxicity evaluation of the corresponding vinorelbine analogues. | Bioorganic & medicinal chemistry letters 20120515 |
| [Effects of water stress and nitrogen nutrition on regulation of Catharanthus roseus alkaloids metabolism]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120501 |
| A virus-induced gene silencing approach to understanding alkaloid metabolism in Catharanthus roseus. | Phytochemistry 20111101 |
| Simultaneous determination of vinblastine and its monomeric precursors vindoline and catharanthine in Catharanthus roseus by capillary electrophoresis-mass spectrometry. | Journal of separation science 20111001 |
| A stereoselective hydroxylation step of alkaloid biosynthesis by a unique cytochrome P450 in Catharanthus roseus. | The Journal of biological chemistry 20110513 |
| Spatial organization of the vindoline biosynthetic pathway in Catharanthus roseus. | Journal of plant physiology 20110415 |
| Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. | Biochemical pharmacology 20110315 |
| Synthesis and study of a molecularly imprinted polymer for the specific extraction of indole alkaloids from Catharanthus roseus extracts. | Analytica chimica acta 20110110 |
| Enhancement of vindoline production in suspension culture of the Catharanthus roseus cell line C20hi by light and methyl jasmonate elicitation. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20110101 |
| [Distribution and accumulation of vindoline, catharanthine and vinblastine in Catharanthus roseus cultivated in China]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101201 |
| Catharanthine C16 substituent effects on the biomimetic coupling with vindoline: preparation and evaluation of a key series of vinblastine analogues. | Bioorganic & medicinal chemistry letters 20101115 |
| Asymmetric total synthesis of vindorosine, vindoline, and key vinblastine analogues. | Journal of the American Chemical Society 20100929 |
| [The characterization on the site of vindoline binding to human serum albumin]. | Yao xue xue bao = Acta pharmaceutica Sinica 20100501 |
| [Monomeric indole alkaloids from the aerial parts of Catharanthus roseus]. | Yao xue xue bao = Acta pharmaceutica Sinica 20100401 |
| Asymmetric total synthesis of vindoline. | Journal of the American Chemical Society 20100324 |
| Elaboration of simplified vinca alkaloids and phomopsin hybrids. | Chemical biology & drug design 20100301 |
| Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues. | Journal of the American Chemical Society 20090408 |
| [Effects of NaCl on the growth and alkaloid content of Catharanthus roseus seedlings]. | Ying yong sheng tai xue bao = The journal of applied ecology 20081001 |
| Vindoline formation in shoot cultures of Catharanthus roseus is synchronously activated with morphogenesis through the last biosynthetic step. | Annals of botany 20080901 |
| John Bryant takes a closer look at some of this month's Original Articles. | Annals of botany 20080901 |
| Inhibitors of tubulin polymerization: synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III. | Bioorganic & medicinal chemistry 20080601 |
| The leaf epidermome of Catharanthus roseus reveals its biochemical specialization. | The Plant cell 20080301 |
| Direct coupling of catharanthine and vindoline to provide vinblastine: total synthesis of (+)- and ent-(-)-vinblastine. | Journal of the American Chemical Society 20080116 |
| Optimisation of supercritical fluid extraction of indole alkaloids from Catharanthus roseus using experimental design methodology--comparison with other extraction techniques. | Phytochemical analysis : PCA 20080101 |
| Application of carborundum abrasion for investigating the leaf epidermis: molecular cloning of Catharanthus roseus 16-hydroxytabersonine-16-O-methyltransferase. | The Plant journal : for cell and molecular biology 20080101 |
| A simplified procedure for indole alkaloid extraction from Catharanthus roseus combined with a semi-synthetic production process for vinblastine. | Molecules (Basel, Switzerland) 20070705 |
| [Simultaneous determination of vindoline, catharanthine and anhydrovinblastine in Catharanthus roseus by high performance liquid chromatography]. | Se pu = Chinese journal of chromatography 20070701 |
| The Suzuki-Miyaura reaction in the chemical transformations of vindoline. | Acta biochimica Polonica 20070101 |
| Synthesis of C-15 vindoline analogues by palladium-catalyzed cross-coupling reactions. | The Journal of organic chemistry 20060929 |
| Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids. | Journal of the American Chemical Society 20060816 |
| Identification of a low vindoline accumulating cultivar of Catharanthus roseus (L.) G. Don by alkaloid and enzymatic profiling. | Phytochemistry 20060801 |
| Localization of tabersonine 16-hydroxylase and 16-OH tabersonine-16-O-methyltransferase to leaf epidermal cells defines them as a major site of precursor biosynthesis in the vindoline pathway in Catharanthus roseus. | The Plant journal : for cell and molecular biology 20051101 |
| Simultaneous determination of vincristine, vinblastine, catharanthine, and vindoline in leaves of catharanthus roseus by high-performance liquid chromatography. | Journal of chromatographic science 20051001 |
| Total synthesis of (-)- and ent-(+)-vindoline. | Organic letters 20050929 |
| Intramolecular [3 + 2]-cycloaddition reaction of push-pull dipoles across heteroaromatic pi-systems. | Organic letters 20040916 |
| Vindoline and 16-demethoxyvindoline: two catharanthus-derived alkaloids. | Acta crystallographica. Section C, Crystal structure communications 20040501 |
| Vindoline synthesis in in vitro shoot cultures of Catharanthus roseus. | Biotechnology letters 20040401 |
| Catharanthus roseus L. plants and explants infected with phytoplasmas: alkaloid production and structural observations. | Protoplasma 20040301 |
| Alkaloid metabolism in wounded Catharanthus roseus seedlings. | Plant physiology and biochemistry : PPB 20040101 |
| Novel bisindole derivatives of Catharanthus alkaloids with potential cytotoxic properties. | Advances in experimental medicine and biology 20030101 |
| Vindoline biosynthesis is transcriptionally blocked in Catharanthus roseus cell suspension cultures. | Molecular biotechnology 20020901 |
| Indole synthesis by radical cyclization of o-alkenylphenyl isocyanides and its application to the total synthesis of natural products. | Chemical record (New York, N.Y.) 20020101 |
| Syntheses of 5a'-homo-vinblastine and congeners designed to establish structural determinants for isolation of atropisomers. | The Journal of organic chemistry 20010810 |