Home Carboxys (2S,3S,4S,5R,6S)-6-[(5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

(2S,3S,4S,5R,6S)-6-[(5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

CAS No.:
21967-41-9
Catalog Number:
AG00I49P
Molecular Formula:
C21H18O11
Molecular Weight:
446.3610
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$25
- +
25g
98%
In Stock USA
United States
$88
- +
100g
98%
In Stock USA
United States
$313
- +
Product Description
Catalog Number:
AG00I49P
Chemical Name:
(2S,3S,4S,5R,6S)-6-[(5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
CAS Number:
21967-41-9
Molecular Formula:
C21H18O11
Molecular Weight:
446.3610
MDL Number:
MFCD00134418
IUPAC Name:
(2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
InChI:
InChI=1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1
InChI Key:
IKIIZLYTISPENI-ZFORQUDYSA-N
SMILES:
OC(=O)[C@H]1O[C@@H](Oc2cc3oc(cc(=O)c3c(c2O)O)c2ccccc2)[C@@H]([C@H]([C@@H]1O)O)O
EC Number:
606-866-1
UNII:
347Q89U4M5
Properties
Complexity:
748  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Defined Bond Stereocenter Count:
0
Exact Mass:
446.085g/mol
Formal Charge:
0
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0
Molecular Weight:
446.364g/mol
Monoisotopic Mass:
446.085g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
183A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.1  
Literature
Title Journal
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Flavonoids induce the expression of acetylcholinesterase in cultured osteoblasts. Chemico-biological interactions 20161125
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Baicalin protects human skin fibroblasts from ultraviolet A radiation-induced oxidative damage and apoptosis. Free radical research 20121201
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Baicalin as a potentially promising drug for the management of sulfur mustard induced cutaneous complications: a review of molecular mechanisms. Cutaneous and ocular toxicology 20120901
Jasmonic acid (JA) acts as a signal molecule in LaCl(3)-induced baicalin synthesis in Scutellaria baicalensis seedlings. Biological trace element research 20120901
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Baicalin improved the spatial learning ability of global ischemia/reperfusion rats by reducing hippocampal apoptosis. Brain research 20120827
A rapid fluorescent screening method for cellular sensitivity to anti-cancer compound. Cytotechnology 20120801
The anticonvulsant and neuroprotective effects of baicalin on pilocarpine-induced epileptic model in rats. Neurochemical research 20120801
Variations in target gene expression and pathway profiles in the mouse hippocampus following treatment with different effective compounds for ischemia-reperfusion injury. Naunyn-Schmiedeberg's archives of pharmacology 20120801
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Baicalin protects mice from Staphylococcus aureus pneumonia via inhibition of the cytolytic activity of α-hemolysin. The Journal of infectious diseases 20120715
'Effects of baicalin on protease-activated receptor-1 expression and brain injury in a rat model of intracerebral hemorrhage'. The Chinese journal of physiology 20120630
Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. Journal of ethnopharmacology 20120626
Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Annals of internal medicine 20120619
DNA microarray expression analysis of baicalin-induced differentiation of C17.2 neural stem cells. Chembiochem : a European journal of chemical biology 20120618
Hypolipidemic and antioxidant effects of hydroxycinnamic acids, quercetin, and cyanidin 3-glucoside in hypercholesterolemic erythrocytes (in vitro study). European journal of nutrition 20120601
Baicalin reduces the permeability of the blood-brain barrier during hypoxia in vitro by increasing the expression of tight junction proteins in brain microvascular endothelial cells. Journal of ethnopharmacology 20120601
Development of an LC-MS method for determination of three active constituents of Shuang-huang-lian injection in rat plasma and its application to the drug interaction study of Shuang-huang-lian freeze-dried powder combined with levofloxacin injection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120601
A novel UPLC-MS/MS method for simultaneous quantification of rhein, emodin, berberine and baicalin in rat plasma and its application in a pharmacokinetic study. Bioanalysis 20120601
Scutellaria baicalensis alleviates cantharidin-induced rat hemorrhagic cystitis through inhibition of cyclooxygenase-2 overexpression. Molecules (Basel, Switzerland) 20120525
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry 20120524
Sensitive detection of hydroxylamine at a simple baicalin carbon nanotubes modified electrode. Talanta 20120515
Integrated pharmacokinetics of major bioactive components in MCAO rats after oral administration of Huang-Lian-Jie-Du-Tang. Journal of ethnopharmacology 20120507
Detection of baicalin metabolites baicalein and oroxylin-a in mouse pancreas and pancreatic xenografts. Pancreas 20120501
Rotenone-induced death of RGC-5 cells is caspase independent, involves the JNK and p38 pathways and is attenuated by specific green tea flavonoids. Neurochemical research 20120501
Baicalin is anti-inflammatory in cigarette smoke-induced inflammatory models in vivo and in vitro: A possible role for HDAC2 activity. International immunopharmacology 20120501
Role of baicalin in regulating Toll-like receptor 2/4 after ischemic neuronal injury. Chinese medical journal 20120501
[Synthesis of baicalin-copper and baicalin-aluminium complex and its bioactivity]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120501
Iron overload-induced rat liver injury: Involvement of protein tyrosine nitration and the effect of baicalin. European journal of pharmacology 20120405
Baicalin down-regulates the expression of macrophage migration inhibitory factor (MIF) effectively for rats with ulcerative colitis. Phytotherapy research : PTR 20120401
San-Huang-Xie-Xin-Tang protects cardiomyocytes against hypoxia/reoxygenation injury via inhibition of oxidative stress-induced apoptosis. Journal of natural medicines 20120401
PPARγ activation by baicalin suppresses NF-κB-mediated inflammation in aged rat kidney. Biogerontology 20120401
Rosmarinic acid and baicalin epigenetically derepress peroxisomal proliferator-activated receptor γ in hepatic stellate cells for their antifibrotic effect. Hepatology (Baltimore, Md.) 20120401
Inhibitory activities of baicalin against renin and angiotensin-converting enzyme. Pharmaceutical biology 20120401
Autophagy induced by baicalin involves downregulation of CD147 in SMMC-7721 cells in vitro. Oncology reports 20120401
Pharmacokinetic study of baicalein after oral administration in monkeys. Fitoterapia 20120401
Deep sequencing of plant and animal DNA contained within traditional Chinese medicines reveals legality issues and health safety concerns. PLoS genetics 20120401
Chemical constituents of the aerial parts of Scutellaria lateriflora and their alpha-glucosidase inhibitory activities. Natural product communications 20120401
[Screening based on response surface methodology of multi-fractions traditional Chinese medicine with anti-influenza virus neuraminidase activity: take shuanghuanglian injection as an example]. Yao xue xue bao = Acta pharmaceutica Sinica 20120401
Baicalin induces apoptosis in SW620 human colorectal carcinoma cells in vitro and suppresses tumor growth in vivo. Molecules (Basel, Switzerland) 20120329
Study of dexamethasone, baicalin and octreotide on brain injury of rats with severe acute pancreatitis. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120301
[Effects of three fungicides on arbuscular mycorrhizal fungal infection and growth of Scutellaria baicalensis Georgi]. Huan jing ke xue= Huanjing kexue 20120301
Baicalin suppresses expression of TLR2/4 and NF-κB in chlamydia trachomatis-infected mice. Immunopharmacology and immunotoxicology 20120201
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Baicalin promotes neuronal differentiation of neural stem/progenitor cells through modulating p-stat3 and bHLH family protein expression. Brain research 20120106
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Anti-inflammatory effects of active constituents extracted from Chinese medicinal herbs against Propionibacterium acnes. Natural product research 20120101
Effect of baicalin on toll-like receptor 4-mediated ischemia/reperfusion inflammatory responses in alcoholic fatty liver condition. Toxicology and applied pharmacology 20120101
NMR studies of protein-ligand interactions. Methods in molecular biology (Clifton, N.J.) 20120101
Involvement of specific transport system on uptake of lactone form of SN-38 in human intestinal epithelial cell line Caco-2. Biological & pharmaceutical bulletin 20120101
Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle. Evidence-based complementary and alternative medicine : eCAM 20120101
Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism. Chinese medicine 20120101
Enhanced effects of cigarette smoke extract on inflammatory cytokine expression in IL-1β-activated human mast cells were inhibited by Baicalein via regulation of the NF-κB pathway. Clinical and molecular allergy : CMA 20120101
Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174T cells. Marine drugs 20120101
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Yang-Dan-Tang, Identified from 15 Chinese Herbal Formulae, Inhibits Human Lung Cancer Cell Proliferation via Cell Cycle Arrest. Evidence-based complementary and alternative medicine : eCAM 20120101
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Water deficit affected flavonoid accumulation by regulating hormone metabolism in Scutellaria baicalensis Georgi roots. PloS one 20120101
CaMKKβ is involved in AMP-activated protein kinase activation by baicalin in LKB1 deficient cell lines. PloS one 20120101
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Role of TLR4 and TCR or BCR against baicalin-induced responses in T and B cells. International immunopharmacology 20111201
Comparative studies on interactions of baicalein, baicalin and scutellarin with lysozyme. European journal of medicinal chemistry 20111201
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[Immunoregulatory mechanisms of an optimal Chinese herbal monomer compound in mice with allergic rhinitis]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20111201
Study of degradation behavior of baicalin during simulative blood sample processing with solid phase extraction technology and identification of the degradation product. Drug metabolism letters 20111201
Toxicological aspects of the use of phenolic compounds in disease prevention. Interdisciplinary toxicology 20111201
[Absorption of flavones in Gegenqinlian decoction and different compatibilities in rat everted gut scas]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111201
[Quadratic regression-orthogonal design optimization ethanol extraction craft of baicalin]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20111201
[Effect of baicalin on liver fatty acid binding protein in oxidative stress model in vitro]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20111201
Enhanced bioavailability after oral and pulmonary administration of baicalein nanocrystal. International journal of pharmaceutics 20111125
Effect of baicalin on matrix metalloproteinase-9 expression and blood-brain barrier permeability following focal cerebral ischemia in rats. Neurochemical research 20111101
Using baicalin-functionalized magnetic nanoparticles for selectively extracting flavonoids from Rosa chinensis. Journal of separation science 20111101
[In-line monitoring of blending process of Zhongsheng pill powder using miniature near-infrared analyzer]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111101
Study of the chemical composition and antimicrobial activities of ethanolic extracts from roots of Scutellaria baicalensis Georgi. Journal of agricultural and food chemistry 20111026
Baicalin inhibits TLR2/4 signaling pathway in rat brain following permanent cerebral ischemia. Inflammation 20111001
Baicalein inhibits the migration and invasive properties of human hepatoma cells. Toxicology and applied pharmacology 20110915
Development of a combined technique using a rapid one-step immunochromatographic assay and indirect competitive ELISA for the rapid detection of baicalin. Analytica chimica acta 20110909
Simultaneous quantification of twelve active components in Yiqing granule by ultra-performance liquid chromatography: application to quality control study. Biomedical chromatography : BMC 20110901
Enhancement of flavone levels through overexpression of chalcone isomerase in hairy root cultures of Scutellaria baicalensis. Functional & integrative genomics 20110901
Comparison of the network structural characteristics of calcium signaling pathway in cerebral ischemia after intervention by different components of Chinese medicine. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20110901
[Effects of baicalin against oxidative stress injury of SH-SY5Y cells by up-regulating SIRT1]. Yao xue xue bao = Acta pharmaceutica Sinica 20110901
[Correlation between change of immunotoxicology indexes of cerum and the occurrence of anaphylaxis in patients induced by qingkailing injection: a clinical study]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110901
Development of a novel method combining HPLC fingerprint and multi-ingredients quantitative analysis for quality evaluation of traditional Chinese medicine preparation. Talanta 20110815
Baicalin, a flavone, induces the differentiation of cultured osteoblasts: an action via the Wnt/beta-catenin signaling pathway. The Journal of biological chemistry 20110812
Baicalin induces human mucoepidermoid carcinoma Mc3 cells apoptosis in vitro and in vivo. Investigational new drugs 20110801
Involvement of GABAergic non-benzodiazepine sites in the anxiolytic-like and sedative effects of the flavonoid baicalein in mice. Behavioural brain research 20110801
Gelucire44/14 as a novel absorption enhancer for drugs with different hydrophilicities: in vitro and in vivo improvement on transcorneal permeation. Journal of pharmaceutical sciences 20110801
The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. Toxicology and applied pharmacology 20110801
Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells. Biochimica et biophysica acta 20110801
[Effects of baicalin on apoptosis in rats with autoimmune encephalomyelitis]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20110801
[Comparision of adsorption-desorption dynamics of huanglian jiedu decoction using different macroporous resins combinations]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110801
[Effects of PEG stress on flavonoids accumulation and related gene expression in suspension of Scutellaria baicalensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110801
[Effects of AM fungi on growth and microelement of Scuteliaria baiealensis under different applied phosphorous levels]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110801
New 3',8''-linked biflavonoids from Selaginella uncinata displaying protective effect against anoxia. Molecules (Basel, Switzerland) 20110725
Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways. Brain research bulletin 20110715
Simultaneous quantification of multiple active components from Xiexin decoction in rat plasma by LC-ESI-MS/MS: application in pharmacokinetics. Biomedical chromatography : BMC 20110701
Protective effects of baicalin and quercetin on an iron-overloaded mouse: comparison of liver, kidney and heart tissues. Natural product research 20110701
[Establishment and applicability evaluation of animal model which was suitable to evaluate immediate hypersensitivity induced by injections of traditional Chinese medicine in BN rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110701
[Material and mechanisms for evaluation of Shuanghuanglian injection induced pseudoanaphylactoid reactions]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110701
[Comparative and correlational studies on contents of flavonoids in axial root and lateral root of Scutellaria baicalensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110701
[Correlation between H2O2 scavenging system and flavonoids accumulation of Scutellaria baicalensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110701
[Study on in situ intestinal absorption of active ingredients in Shuanghuanglian oral liquid in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110701
Baicalin upregulates the genetic expression of antioxidant enzymes in Type-2 diabetic Goto-Kakizaki rats. Life sciences 20110606
Simultaneous determination of eight active components in Chinese medicine 'JiangYaBiFeng' tablet by HPLC coupled with diode array detection. Journal of pharmaceutical and biomedical analysis 20110601
Flavone-catalyzed apoptosis in Scutellaria baicalensis. Phytochemistry 20110601
In vitro synergistic effects of baicalin with oxytetracycline and tetracycline against Staphylococcus aureus. The Journal of antimicrobial chemotherapy 20110601
Convulsion-related activities of Scutellaria flavones are related to the 5,7-dihydroxyl structures. European journal of pharmacology 20110601
Herbal extract THI improves metabolic abnormality in mice fed a high-fat diet. Nutrition research and practice 20110601
Chrysin reduces proliferation and induces apoptosis in the human prostate cancer cell line pc-3. Clinics (Sao Paulo, Brazil) 20110601
Co-administration of subeffective anxiolytic doses of diazepam and hydroxyzine in elevated zero-maze in mice. Psychiatry investigation 20110601
Design and evaluation of baicalin-containing in situ pH-triggered gelling system for sustained ophthalmic drug delivery. International journal of pharmaceutics 20110530
Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation. Journal of ethnopharmacology 20110517
Evaluating pulmonary toxicity of Shuang-Huang-Lian in vitro and in vivo. Journal of ethnopharmacology 20110517
The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway. Journal of ethnopharmacology 20110517
Effects of baicalein on Sendai virus in vivo are linked to serum baicalin and its inhibition of hemagglutinin-neuraminidase. Archives of virology 20110501
Pharmacokinetics of baicalin-phospholipid complex in rat plasma and brain tissues after intranasal and intravenous administration. Die Pharmazie 20110501
[Baicalin suppresses beta-amyloid protein induced hippocampal cyclooxygenase-2 expression]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110501
Preparation and characterization of baicalin-poly -vinylpyrrolidone coprecipitate. International journal of pharmaceutics 20110415
Anti-inflammatory effects of Huang-Lian-Jie-Du decoction, its two fractions and four typical compounds. Journal of ethnopharmacology 20110412
[Effects of baicalin on pulmonary functions of acute respiratory distress syndrome induced by oleic acid in rats]. Zhonghua yi xue za zhi 20110412
Evaluation of quality control strategies in Scutellaria herbal medicines. Journal of pharmaceutical and biomedical analysis 20110405
Preparation and evaluation of solid lipid nanoparticles of baicalin for ocular drug delivery system in vitro and in vivo. Drug development and industrial pharmacy 20110401
Diabetes is an inflammatory disease: evidence from traditional Chinese medicines. Diabetes, obesity & metabolism 20110401
Baicalin prevents the production of hydrogen peroxide and oxidative stress induced by Aβ aggregation in SH-SY5Y cells. Neuroscience letters 20110401
[Simultaneous determination of four active compounds in tiangou capsules by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110401
[A novel method for fast determination of components in Guizhi Fuling capsule by near infrared spectroscopy]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110401
[Study on transportation of Xiaochaihu Tang in Caco-2 cell model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110401
Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product. Journal of pharmaceutical and biomedical analysis 20110325
Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. Planta medica 20110301
[Antagonism of baicalin on cell cyclical distribution and cell apoptosis in A549 cells infected with influenza A (H1N1) virus]. Bing du xue bao = Chinese journal of virology 20110301
[Study on dispersivity of baicalin solid dispersion by vibrational spectrometry]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110301
Neuronal differentiation of C17.2 neural stem cells induced by a natural flavonoid, baicalin. Chembiochem : a European journal of chemical biology 20110211
Antihyperglycemic effects of baicalin on streptozotocin - nicotinamide induced diabetic rats. Phytotherapy research : PTR 20110201
Baicalin increases VEGF expression and angiogenesis by activating the ERR{alpha}/PGC-1{alpha} pathway. Cardiovascular research 20110201
Protective effect of baicalin against multiple ultraviolet B exposure-mediated injuries in C57BL/6 mouse skin. Archives of pharmacal research 20110201
[The enhancing effect of Angelica dahurica extracts on absorption of baicalin--the active composition of Scutellaria]. Yao xue xue bao = Acta pharmaceutica Sinica 20110201
Hypericum triquetrifolium-Derived Factors Downregulate the Production Levels of LPS-Induced Nitric Oxide and Tumor Necrosis Factor-α in THP-1 Cells. Evidence-based complementary and alternative medicine : eCAM 20110101
Evaluation of oxygen radical absorbance capacity in kampo medicine. Evidence-based complementary and alternative medicine : eCAM 20110101
San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells. Evidence-based complementary and alternative medicine : eCAM 20110101
Prescriptions of Chinese Herbal Medicines for Insomnia in Taiwan during 2002. Evidence-based complementary and alternative medicine : eCAM 20110101
Maternal baicalin treatment increases fetal lung surfactant phospholipids in rats. Evidence-based complementary and alternative medicine : eCAM 20110101
Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity. Evidence-based complementary and alternative medicine : eCAM 20110101
Analyzing Cytotoxic and Apoptogenic Properties of Scutellaria litwinowii Root Extract on Cancer Cell Lines. Evidence-based complementary and alternative medicine : eCAM 20110101
Protective effects of baicalin on carbon tetrachloride induced liver injury by activating PPARγ and inhibiting TGFβ1. Pharmaceutical biology 20110101
Sairei-to ameliorates rat peritoneal fibrosis partly through suppression of oxidative stress. Nephron. Experimental nephrology 20110101
Ethanol extract of Scutellaria baicalensis Georgi prevents oxidative damage and neuroinflammation and memorial impairments in artificial senescense mice. Journal of biomedical science 20110101
Animal models for periodontal disease. Journal of biomedicine & biotechnology 20110101
The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. International journal of molecular sciences 20110101
Identification of Baicalin as an immunoregulatory compound by controlling T(H)17 cell differentiation. PloS one 20110101
A novel therapeutic regimen for hepatic fibrosis using the combination of mesenchymal stem cells and baicalin. Die Pharmazie 20110101
Docking study of HIV-1 reverse transcriptase with phytochemicals. Bioinformation 20110101
Suppression of low-density lipoprotein oxidation, vascular smooth muscle cell proliferation and migration by a herbal extract of Radix Astragali, Radix Codonopsis and Cortex Lycii. BMC complementary and alternative medicine 20110101
Synergistic antimicrobial activity between pentacyclic triterpenoids and antibiotics against Staphylococcus aureus strains. Annals of clinical microbiology and antimicrobials 20110101
Baicalin induced dendritic cell apoptosis in vitro. Frontiers in pharmacology 20110101
Butin (7,3',4'-trihydroxydihydroflavone) reduces oxidative stress-induced cell death via inhibition of the mitochondria-dependent apoptotic pathway. International journal of molecular sciences 20110101
Esculetin ameliorates carbon tetrachloride-mediated hepatic apoptosis in rats. International journal of molecular sciences 20110101
Neuroprotective effects of flavonoids on hypoxia-, glutamate-, and oxidative stress-induced retinal ganglion cell death. Molecular vision 20110101
Flavocoxid inhibits phospholipase A2, peroxidase moieties of the cyclooxygenases (COX), and 5-lipoxygenase, modifies COX-2 gene expression, and acts as an antioxidant. Mediators of inflammation 20110101
Anti-cancer natural products isolated from chinese medicinal herbs. Chinese medicine 20110101
San-Huang-Xie-Xin-Tang Prevents Rat Hearts from Ischemia/Reperfusion-Induced Apoptosis through eNOS and MAPK Pathways. Evidence-based complementary and alternative medicine : eCAM 20110101
Herbal medicine and hepatocellular carcinoma: applications and challenges. Evidence-based complementary and alternative medicine : eCAM 20110101
Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons. BMC neuroscience 20110101
Hwangryunhaedoktang in adult patients with atopic dermatitis: a randomised, double-blind, placebo-controlled, two-centre trial--study protocol. BMC complementary and alternative medicine 20110101
Tissue-specific Salmonella Typhimurium gene expression during persistence in pigs. PloS one 20110101
Comparative chemical and statistical analysis of cultivated and wild Radix Scutellariae. The American journal of Chinese medicine 20110101
A 4-week Repeated Dose Oral Toxicity and Cytotoxicity Study of Gumiganghwaltang in Crl:CD (SD) Rats. Toxicology international 20110101
Stuck at the bench: Potential natural neuroprotective compounds for concussion. Surgical neurology international 20110101
Oxidative stress in neurodegenerative diseases: mechanisms and therapeutic perspectives. Oxidative medicine and cellular longevity 20110101
Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives. Pharmacognosy reviews 20110101
Protective effects of baicalin against ischemia/reperfusion injury in rat liver. Journal of natural products 20101227
[Baicalin prevents the up-regulation of connective tissue growth factor in fibrotic lungs of rats]. Sheng li xue bao : [Acta physiologica Sinica] 20101225
Baicalin attenuates focal cerebral ischemic reperfusion injury through inhibition of nuclear factor κB p65 activation. Biochemical and biophysical research communications 20101217
Comprehensive study of baicalin down-regulating NOD2 receptor expression of neurons with oxygen-glucose deprivation in vitro and cerebral ischemia-reperfusion in vivo. European journal of pharmacology 20101215
Molecular cloning and characterization of phenylalanine ammonia-lyase, cinnamate 4-hydroxylase and genes involved in flavone biosynthesis in Scutellaria baicalensis. Bioresource technology 20101201
Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry. Chemistry & biodiversity 20101201
[Effect of baicalin on protease-activated receptor-1 expression and cell apoptosis in brain of rat with intracerebral hemorrhage]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20101201
[Inhibitory effect of baicalin on germ tube formation and adhesion of Candida albicans]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101201
[Effect of baicalin on pharmacokinetics of chlorogenic acid in rabbits]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101201
[Bio-activity evaluation of Qinlian Siwu decoction on inhibiting mice uterine contraction in vitro and its components analysis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101201
Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese medicinal preparations containing scutellaria-coptis herb couple. Journal of pharmaceutical and biomedical analysis 20101102
Application of near infrared spectroscopy for rapid analysis of intermediates of Tanreqing injection. Journal of pharmaceutical and biomedical analysis 20101102
Secondary metabolite mapping identifies Scutellaria inhibitors of human lung cancer cells. Journal of pharmaceutical and biomedical analysis 20101102
Baicalin inhibits PDGF-BB-stimulated vascular smooth muscle cell proliferation through suppressing PDGFRβ-ERK signaling and increase in p27 accumulation and prevents injury-induced neointimal hyperplasia. Cell research 20101101
HPLC determination of five polyphenols in rat plasma after intravenous administration of hawthorn leaves extract and its application to pharmacokinetic study. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101101
[Capillary electrophoresis fingerprint of chaihu shugan pill and determination of baicalin content in chaihu shugan pill]. Se pu = Chinese journal of chromatography 20101101
Neuroprotective effect of baicalin on compression spinal cord injury in rats. Brain research 20101021
Binding modes of flavones to human serum albumin: insights from experimental and computational studies. The journal of physical chemistry. B 20101014
Baicalin attenuates inflammation by inhibiting NF-kappaB activation in cigarette smoke induced inflammatory models. Pulmonary pharmacology & therapeutics 20101001
Comparative pharmacokinetics of baicalin in plasma after oral administration of Huang-Lian-Jie-Du-Tang or pure baicalin in MCAO and sham-operated rats. Fitoterapia 20100901
Inhibitory effects of baicalin on IL-1beta- induced MMP-1/TIMP-1 and its stimulated effect on collagen-I production in human periodontal ligament cells. European journal of pharmacology 20100901
Therapeutic effects of Baicalein on atopic dermatitis-like skin lesions of NC/Nga mice induced by dermatophagoides pteronyssinus. International immunopharmacology 20100901
[Baicalin regulates lipid metabolism in high-fat feeding SD rat liver and the mechanism involves modulation of AMPK-alpha pathway]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20100901
[Determination of baicalin in Shuanghuanglian oral liquid on composite mercury film electrode based on chemical modified]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901
[Similarity and diversity analysis of qingkailing effective components in regulating hippocampus ischemia-related genes of mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901
Evaluation of antioxidant and inhibitory activities for different subclasses flavonoids on enzymes for rheumatoid arthritis. Journal of food science 20100901
Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways. European journal of pharmacology 20100825
Comparative pharmacokinetics of baicalin and wogonoside by liquid chromatography-mass spectrometry after oral administration of Xiaochaihu Tang and Radix scutellariae extract to rats. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100815
Beta-Catenin mediates the anti-adipogenic effect of baicalin. Biochemical and biophysical research communications 20100806
UPLC-PDA-TOFMS based chemical profiling approach to rapidly evaluate chemical consistency between traditional and dispensing granule decoctions of traditional medicine combinatorial formulae. Journal of pharmaceutical and biomedical analysis 20100801
Combinative method using HPLC fingerprint and quantitative analyses for quality consistency evaluation of an herbal medicinal preparation produced by different manufacturers. Journal of pharmaceutical and biomedical analysis 20100801
An LC-MS/MS method for the simultaneous determination of chlorogenic acid, forsythiaside A and baicalin in rat plasma and its application to pharmacokinetic study of shuang-huang-lian in rats. Journal of pharmaceutical and biomedical analysis 20100801
Baicalin, a flavonoid from Scutellaria baicalensis Georgi, activates large-conductance Ca2+-activated K+ channels via cyclic nucleotide-dependent protein kinases in mesenteric artery. Phytomedicine : international journal of phytotherapy and phytopharmacology 20100801
Separation of flavonoid and alkaloid using collagen fiber adsorbent. Journal of separation science 20100801
Effect of low molecular weight chitosans on drug permeation through mouse skin: 1. Transdermal delivery of baicalin. Journal of pharmaceutical sciences 20100701
[Simultaneous determination of berberine, palmatine, matrine, catechin and baicalin in Funing Shuan by micellar electrokinetic capillary chromatography-electrospray ionization mass spectrometry]. Se pu = Chinese journal of chromatography 20100701
[Prescription design and dissolution evaluation of self-emulsifying drug delivery systems of baicalin]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100701
Anti-nociceptive mechanism of baicalin involved in intervention of TRPV1 in DRG neurons in vitro. Journal of ethnopharmacology 20100616
Baicalin protects thymus of rats with severe acute pancreatitis. Inflammation 20100601
Multiple therapeutic effects of adjunctive baicalin therapy in experimental bacterial meningitis. Inflammation 20100601
Anti-pruritic effect of baicalin and its metabolites, baicalein and oroxylin A, in mice. Acta pharmacologica Sinica 20100601
LC determination and pharmacokinetic study of hyperoside in rat plasma after intravenous administration. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100601
[Optimal combination of baicalin, icariin and Astragalus saponin I from a Chinese herbal compound Biminne]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20100601
Computational investigation of the anti-HIV activity of Chinese medicinal formula Three-Huang Powder. Interdisciplinary sciences, computational life sciences 20100601
[Preparation and quality evaluation of fufangxiaoyepipa dispersible tablets]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100601
Inhibitors of prolyl oligopeptidases for the therapy of human diseases: defining diseases and inhibitors. Journal of medicinal chemistry 20100513
Antiallergic herbal composition from Scutellaria baicalensis and Phyllostachys edulis. Planta medica 20100501
90-day oral toxicity study of UP446, a combination of defined extracts of Scutellaria baicalensis and Acacia catechu, in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100501
Baicalin, an emerging multi-therapeutic agent: pharmacodynamics, pharmacokinetics, and considerations from drug development perspectives. Xenobiotica; the fate of foreign compounds in biological systems 20100501
[Optimization of combination modes of medical materials in extract of Huanglian Jiedu decoction by semi-bionic extraction]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100501
Rapid in vivo screening system for anti-oxidant activity using bacterial redox sensor strains. Journal of applied microbiology 20100401
[Efffect of baicalin on antipyresis and influence on cytokine]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100401
Simultaneous determination of five marker constituents in Ssanghwa tang by HPLC/DAD. Pharmacognosy magazine 20100401
Baicalin suppresses lung carcinoma and lung metastasis by SOD mimic and HIF-1alpha inhibition. European journal of pharmacology 20100325
On-line continuous flow ultrasonic extraction coupled with high performance liquid chromatographic separation for determination of the flavonoids from root of Scutellaria baicalensis Georgi. Journal of chromatography. A 20100319
The anti-inflammatory effect of baicalin on hypoxia/reoxygenation and TNF-alpha induced injury in cultural rat cardiomyocytes. Phytotherapy research : PTR 20100301
Baicalin released from Scutellaria baicalensis induces autotoxicity and promotes soilborn pathogens. Journal of chemical ecology 20100301
[In vitro activity of baicalin against non-albicans Candida biofilms]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100301
[Effects of light on flavonoids accumulation and related gene expression in suspension cultures of Scutellaria baicalensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100301
[Simultaneous determination of five active constitutents in Xiaochaihu Tang by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100301
[An in vitro analytical method based on bio-thermal activity for the determination of dissolution rate of Chinese medicine solid preparation]. Yao xue xue bao = Acta pharmaceutica Sinica 20100301
Qualitative and quantitative analysis of traditional Chinese medicine Niu Huang Jie Du Pill using ultra performance liquid chromatography coupled with tunable UV detector and rapid resolution liquid chromatography coupled with time-of-flight tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis 20100205
Screening of Kit inhibitors: suppression of Kit signaling and melanogenesis by emodin. Phytotherapy research : PTR 20100201
Inhibitory effect of baicalein on IL-6-mediated signaling cascades in human myeloma cells. European journal of haematology 20100201
Baicalin attenuates oxygen-glucose deprivation-induced injury by inhibiting oxidative stress-mediated 5-lipoxygenase activation in PC12 cells. Acta pharmacologica Sinica 20100201
Effect of baicalein from Scutellaria baicalensis on prevention of noise-induced hearing loss. Neuroscience letters 20100129
Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. Phytomedicine : international journal of phytotherapy and phytopharmacology 20100101
Effects of baicalin on Chlamydia trachomatis infection in vitro. Planta medica 20100101
Increased oral AUC of baicalin in streptozotocin-induced diabetic rats due to the increased activity of intestinal beta-glucuronidase. Planta medica 20100101
Ocular pharmacokinetic study on baicalin in lens of rabbits following intragastric administration. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20100101
Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells. Phytomedicine : international journal of phytotherapy and phytopharmacology 20100101
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids. Bioorganic & medicinal chemistry 20100101
Inhibitory effects of baicalein on the influenza virus in vivo is determined by baicalin in the serum. Biological & pharmaceutical bulletin 20100101
Inhibition of prostaglandin E2 production by flavone and its related compounds. In vivo (Athens, Greece) 20100101
[Preliminary study to investigate dynamic extract process of Huanglian Jiedu Tang and the mechanism of subsidence produce]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100101
[Determination content of baicalin in Yinhuang granules from different pharmaceutical factories by near-infrared spectroscopy]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100101
Impacts of recent cultivation on genetic diversity pattern of a medicinal plant, Scutellaria baicalensis (Lamiaceae). BMC genetics 20100101
Apoptotic effects of chrysin in human cancer cell lines. International journal of molecular sciences 20100101
Rhizoma Coptidis inhibits LPS-induced MCP-1/CCL2 production in murine macrophages via an AP-1 and NFkappaB-dependent pathway. Mediators of inflammation 20100101
Banha-sasim-tang as an herbal formula for the treatment of functional dyspepsia: a randomized, double-blind, placebo-controlled, two-center trial. Trials 20100101
A comprehensive platform for quality control of botanical drugs (PhytomicsQC): a case study of Huangqin Tang (HQT) and PHY906. Chinese medicine 20100101
Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells. Journal of experimental & clinical cancer research : CR 20100101
Baicalin inhibits free radicals processes initiated by chromium ions. Acta poloniae pharmaceutica 20100101
Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cells. International journal of molecular sciences 20100101
Applications of chitin and its derivatives in biological medicine. International journal of molecular sciences 20100101
Molecular cloning and expression profiling of a chalcone synthase gene from hairy root cultures of Scutellaria viscidula Bunge. Genetics and molecular biology 20100101
Hepatic contribution to a marked increase in the plasma concentration of baicalin after oral administration of its aglycone, baicalein, in multidrug resistance-associated protein 2-deficient rat. Biological & pharmaceutical bulletin 20091201
The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells. Acta pharmacologica Sinica 20091201
Cloning and expression of beta-glucuronidase from Lactobacillus brevis in E. coli and application in the bioconversion of baicalin and wogonoside. Journal of microbiology and biotechnology 20091201
[A quantitative method for simultaneous assay of four flavones with one marker in Radix Scutellariae]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201
[Qualitative analysis of the main chemical constituents of shuanghuanglian injection powder and their origin by HPLC-ESI/MS/MS spectrometry]. Yao xue xue bao = Acta pharmaceutica Sinica 20091201
Arsenic accumulation in Scutellaria baicalensis Georgi and its effects on plant growth and pharmaceutical components. Journal of hazardous materials 20091115
Effect of baicalin and octreotide on the expression levels of P-selectin protein in multiple organs of rats with severe acute pancreatitis. Journal of gastroenterology and hepatology 20091101
Antiobesity effect of baicalin involves the modulations of proadipogenic and antiadipogenic regulators of the adipogenesis pathway. Phytotherapy research : PTR 20091101
[Intestinal absorption and secretion mechanism of carboxylate drugs]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20091101
Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet. Acta pharmacologica Sinica 20091101
[Analysis of main flavonoids contents of Scutellaria baicalensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091101
[Flavonoids from Scutellaria baicalensis and their bioactivities]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20091018
Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix Scutellariae. Journal of pharmaceutical and biomedical analysis 20091015
Correlation between anti-fibrotic effect of baicalin and serum cytokines in rat hepatic fibrosis. World journal of gastroenterology 20091007
Acupuncture can improve absorption of baicalin from extracts of Scutellaria baicalensis Georgi in rats. Phytotherapy research : PTR 20091001
In vitro anti-fibrotic activities of herbal compounds and herbs. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091001
Baicalin suppresses expression of Chlamydia protease-like activity factor in Hep-2 cells infected by Chlamydia trachomatis. Fitoterapia 20091001
Effects of Labrasol on the corneal drug delivery of baicalin. Drug delivery 20091001
Effect of baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis. Pancreas 20091001
Baicalin reduces mitochondrial damage in streptozotocin-induced diabetic Wistar rats. Diabetes/metabolism research and reviews 20091001
Influence of coptis Chinensis on pharmacokinetics of flavonoids after oral administration of radix Scutellariae in rats. Biopharmaceutics & drug disposition 20091001
Mitigation of acute ultraviolet B radiation-mediated damages by baicalin in mouse skin. Photodermatology, photoimmunology & photomedicine 20091001
[Effects of baicalin on proliferation and apoptosis of adriamycin-resistant human leukemia HL-60/ADR cells]. Zhongguo shi yan xue ye xue za zhi 20091001
[Study on the technics of adsorption and purification of baicalin by different macroporous resins]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20091001
Neuroprotective effect of baicalin in a rat model of permanent focal cerebral ischemia. Neurochemical research 20090901
Effect of the glycosylation of flavonoids on interaction with protein. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090901
Quick and sensitive determination of flavonoids by capillary electrophoresis-potential gradient detection. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090901
[Determination of baicalin and total flavonoids in Radix scutellariae by near infrared diffuse reflectance spectroscopy]. Guang pu xue yu guang pu fen xi = Guang pu 20090901
[Primary study on mechanism of baicalin on the Th1/Th2 response in murine model of asthma]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090901
Effective constituents in Xiexin Decoction for anti-inflammation. Journal of ethnopharmacology 20090817
Preparation and characterization of the inclusion complex of Baicalin (BG) with beta-CD and HP-beta-CD in solution: an antioxidant ability study. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090815
Baicalin in radical scavenging and its synergistic effect with beta-carotene in antilipoxidation. Journal of agricultural and food chemistry 20090812
Simultaneous determination of six herbal components in intestinal perfusate by high-performance liquid chromatography. Biomedical chromatography : BMC 20090801
Flavocoxid, a dual inhibitor of cyclooxygenase and 5-lipoxygenase, blunts pro-inflammatory phenotype activation in endotoxin-stimulated macrophages. British journal of pharmacology 20090801
[Study on effects of baicalin, berberine and Astragalus polysaccharides and their combinative effects on aldose reductase in vitro]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090801
Baicalin administration is effective in positive regulation of twenty-four ischemia/reperfusion-related proteins identified by a proteomic study. Neurochemistry international 20090701
Simultaneous determination of puerarin, daidzein, baicalin, wogonoside and liquiritin of GegenQinlian decoction in rat plasma by ultra-performance liquid chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090701
Selection of the optimal solvent grade for the mobile phase in HPLC with electrochemical detection based on FUMI theory. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090701
Analysis of fuzhisan and quantitation of baicalin and ginsenoside Rb(1) by HPLC-DAD-ELSD. Archives of pharmacal research 20090701
Nitrite-glucose-glucose oxidase system directly induces rat heart homogenate oxidation and tyrosine nitration: effects of some flavonoids. Toxicology in vitro : an international journal published in association with BIBRA 20090601
Effects of Baicalin and Octreotide on the serum TNF-alpha level and apoptosis in multiple organs of rats with severe acute pancreatitis. Inflammation 20090601
Protective effects of baicalin and octreotide on intestinal mucosa of rats with severe acute pancreatitis. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20090601
[Effects of DSCAM on differentiation of rat marrow mesenchymal stem cells into neurons in vitro]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20090601
Matrix metalloproteinase inhibitors (MMPIs) from marine natural products: the current situation and future prospects. Marine drugs 20090601
[Qualitative and quantitative analysis of Shuanghuanglian fenzhenji by FTIR]. Guang pu xue yu guang pu fen xi = Guang pu 20090601
Baicalin improves antioxidant status of streptozotocin-induced diabetic Wistar rats. Journal of agricultural and food chemistry 20090527
Upregulation of interferon-gamma and interleukin-4, Th cell-derived cytokines by So-Shi-Ho-Tang (Sho-Saiko-To) occurs at the level of antigen presenting cells, but not CD4 T cells. Journal of ethnopharmacology 20090504
Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control. Journal of pharmaceutical and biomedical analysis 20090501
Baicalin attenuates air embolism-induced acute lung injury in rat isolated lungs. British journal of pharmacology 20090501
Flavocoxid is as effective as naproxen for managing the signs and symptoms of osteoarthritis of the knee in humans: a short-term randomized, double-blind pilot study. Nutrition research (New York, N.Y.) 20090501
[Analysis of the 4th generation Scutellaria baicalensis Georgi with space mutagenesis via FTIR spectroscopy]. Guang pu xue yu guang pu fen xi = Guang pu 20090501
[Identification of the authentic quality of Longdanxiegan pill by systematic quantified fingerprint method based on three wavelength fusion chromatogram]. Se pu = Chinese journal of chromatography 20090501
Induction of cytochrome P450 2B6 activity by the herbal medicine baicalin as measured by bupropion hydroxylation. European journal of clinical pharmacology 20090401
[Evaluating the quality of niuhuangjiedu tablets by the systematic quantified fingerprint method]. Yao xue xue bao = Acta pharmaceutica Sinica 20090401
[The nasal mucosa permeability and toxicity of baicalin carrier systems liposomes, beta-cyclodextrin inclusion compound, and phospholipid complex]. Yao xue xue bao = Acta pharmaceutica Sinica 20090401
[Influence of baicalin on TNF-alpha and soluble intercellular adhesion molecule-1 in rats infected with Pneumocystis carinii]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20090401
Simple preparation of baicalin from Scutellariae Radix. Journal of chromatography. A 20090313
Iron-binding and anti-Fenton properties of baicalein and baicalin. Journal of inorganic biochemistry 20090301
The autonomous notch signal pathway is activated by baicalin and baicalein but is suppressed by niclosamide in K562 cells. Journal of cellular biochemistry 20090301
Antioxidative potentiality of a Kampo formulation measured by an ex vivo study. Journal of alternative and complementary medicine (New York, N.Y.) 20090301
Multiple compounds determination and fingerprint analysis of Lidanpaishi tablet and keli by high-performance liquid chromatography. Analytica chimica acta 20090202
Up-regulation of Toll-like receptor 4 was suppressed by emodin and baicalin in the setting of acute pancreatitis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090201
New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. Cancer treatment reviews 20090201
Influence of baicalin and octreotide on NF-kappaB and p-selectin expression in liver and kidney of rats with severe acute pancreatitis. Inflammation 20090201
Pathological changes in multiple organs of rats with severe acute pancreatitis treated by baicalin and octreotide. Hepatobiliary & pancreatic diseases international : HBPD INT 20090201
[Effects of Qingkailing effective components on nuclear factor-kappa B in an ischemia-reperfusion injury model of rat brain microvascular endothelial cells in vitro]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20090201
In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids. Planta medica 20090101
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC medical genomics 20090101
Protective effects of baicalin against bromocriptine induced abortion in mice. The American journal of Chinese medicine 20090101
Mechanical and baicalin delivery properties of adhesive matrices for iontophoretic flexible electrodes. Journal of biomaterials science. Polymer edition 20090101
In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root. Journal of biomedical science 20090101
A new dawn for the use of traditional Chinese medicine in cancer therapy. Molecular cancer 20090101
Simple and reliable methods for the determination of sixteen marker components for quality control of Daochi pill by HPLC coupled with diode array detection. Phytochemical analysis : PCA 20090101
Effect of Scutellariae radix ingredients on prostaglandin E(2) production and COX-2 expression by LPS-activated macrophage. In vivo (Athens, Greece) 20090101
Protective effects of Salvia miltiorrhizae on multiple organs of rats with obstructive jaundice. Mediators of inflammation 20090101
Chinese medicines as a resource for liver fibrosis treatment. Chinese medicine 20090101
Design and evaluation of San-huang dispersible tablet--an efficient delivery system for Traditional Chinese Medicine. Pharmaceutical development and technology 20090101
An in vitro based investigation of the cytotoxic effect of water extracts of the Chinese herbal remedy LD on cancer cells. Chemistry Central journal 20090101
Influence of baicalin on TNF-alpha mRNA, caspase-3 and P-selectin expression in pancreatic tissue of rats with severe acute pancreatitis. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20090101
Therapy for nifedipine-induced gingival overgrowth by Saireito in rats. European journal of medical research 20090101
Protection of Salvia miltiorrhizae to the spleen and thymus of rats with severe acute pancreatitis or obstructive jaundice. Mediators of inflammation 20090101
Whether co-administration of garlic has negative influence on Scutellaria baicalensis Georgi in treating models rats with pelvic inflammation? African journal of traditional, complementary, and alternative medicines : AJTCAM 20090101
Effects of Baicalin on inflammatory mediators and pancreatic acinar cell apoptosis in rats with sever acute pancreatitis. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20090101
Influence of food polyphenols on aryl hydrocarbon receptor-signaling pathway estimated by in vitro bioassay. Phytochemistry 20081201
GABA A receptor subtype selectivity underlying selective anxiolytic effect of baicalin. Neuropharmacology 20081201
The flavonoid baicalin counteracts ischemic and oxidative insults to retinal cells and lipid peroxidation to brain membranes. Neurochemistry international 20081201
[Effect of effective components of huanglian jiedu decoction on hypoxia, reoxygenation injury and the expression of VCAM in cultured rat cerebral microvascular endothelial cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081201
Study on protecting effects of baicalin and octreotide on hepatic injury in rats with severe acute pancreatitis. World journal of gastroenterology 20081114
Optimization of capillary liquid chromatography with electrochemical detection for determining femtogram levels of baicalin and baicalein on the basis of the FUMI theory. Journal of pharmaceutical and biomedical analysis 20081104
[Study on stability of baicalin and baicalein in Rat plasma by HPLC-ECD]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081101
[Adscription of plasma effective constituents of rat after oral administration of gegen qinlian decoction]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081101
[Effect of atractylodes rhizome oil and other volatile oils on percutaneous absorption of baicalin]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20081101
Quick analysis of baicalin in Scutellariae Radix by enzyme-linked immunosorbent assay using a monoclonal antibody. Talanta 20081019
Determination of baicalin in rat cerebrospinal fluid and blood using microdialysis coupled with ultra-performance liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081015
Acupuncture may improve the absorption of baicalin from the extracts of Scutellaria baicalensis Georgi in rats with pelvic inflammation. Forschende Komplementarmedizin (2006) 20081001
Cancer is a preventable disease that requires major lifestyle changes. Pharmaceutical research 20080901
Transport and metabolism of flavonoids from Chinese herbal remedy Xiaochaihu- tang across human intestinal Caco-2 cell monolayers. Acta pharmacologica Sinica 20080901
[Simultaneous determination of five effective components in Qingrejiedu oral liquid using high performance liquid chromatography-mass spectrometry]. Se pu = Chinese journal of chromatography 20080901
Nitrogen-containing flavonoid analogues as CDK1/cyclin B inhibitors: synthesis, SAR analysis, and biological activity. Bioorganic & medicinal chemistry 20080801
Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. Bioorganic & medicinal chemistry 20080801
Protective effect of the Baicalin against DNA damage induced by ultraviolet B irradiation to mouse epidermis. Photodermatology, photoimmunology & photomedicine 20080801
Chemopreventive effect of selenium and Chinese medicinal herbs on N-nitrosobis(2-oxopropyl)amine-induced hepatocellular carcinoma in Syrian hamsters. Liver international : official journal of the International Association for the Study of the Liver 20080701
Baicalin protects human fibroblasts against ultraviolet B-induced cyclobutane pyrimidine dimers formation. Archives of dermatological research 20080701
Comparison of the major flavonoid content of S. baicalensis, S. lateriflora, and their commercial products. Journal of natural medicines 20080701
Genetic characterization and phytochemical analysis of wild and cultivated populations of Scutellaria baicalensis. Chemistry & biodiversity 20080701
[Evaluation of targeting property for Kuikang colon targeted pellets]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080701
[Induction and culture of hairy roots in Scutellaria viscidula and its baicalin production]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080701
[Experimental research on application of hydrodynamic acoustic generator in extraction of Chinese medicine]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080701
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry 20080612
Protective effect of baicalin against lipopolysaccharide/D-galactosamine-induced liver injury in mice by up-regulation of heme oxygenase-1. European journal of pharmacology 20080610
Biotransformation of ginsenoside Rb1, crocin, amygdalin, geniposide, puerarin, ginsenoside Re, hesperidin, poncirin, glycyrrhizin, and baicalin by human fecal microflora and its relation to cytotoxicity against tumor cells. Journal of microbiology and biotechnology 20080601
Effects of Mg-ATP on the flavonoid production in the Scutellaria baicalensis Georgii suspension cultures. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20080601
[In vitro metabolic interconversion between baicalin and baicalein in the liver, kidney, intestine and bladder of rat]. Yao xue xue bao = Acta pharmaceutica Sinica 20080601
[Comparative study on chemcial composition between cultivated and wild Scutellariae radix]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080601
Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells. Biochemical pharmacology 20080515
Blockade of the dioxin pathway by herbal medicine Formula Bupleuri Minor: identification of active entities for suppression of AhR activation. Biological & pharmaceutical bulletin 20080501
[Comparative investigation of the components in rats plasma before and after orally administrating Shuanghuanglian injection]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080501
[Study of Scutellaria baicalensis and Baicalin against antimicrobial susceptibility of Helicobacter pylori strains in vitro]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080501
[Protective effect of baicalin on experimental periodontitis in rats and its possible mechanisms]. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20080501
Structure-activity relationship of human GLO I inhibitory natural flavonoids and their growth inhibitory effects. Bioorganic & medicinal chemistry 20080401
The effect of herbal medicine baicalin on pharmacokinetics of rosuvastatin, substrate of organic anion-transporting polypeptide 1B1. Clinical pharmacology and therapeutics 20080301
Solid-state NMR studies and DFT calculations of flavonoids: baicalein, baicalin and wogonoside. Magnetic resonance in chemistry : MRC 20080301
[Inhibiting effects of denshensu, baicalin, astragalus and Panax notoginseng saponins on hepatic fibrosis and their possible mechanisms]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080301
Comparisons of Scutellaria baicalensis, Scutellaria lateriflora and Scutellaria racemosa: genome size, antioxidant potential and phytochemistry. Planta medica 20080301
[Effect of effective components of Huanglian Jiedu decocting on NF-kappaB in cultured rat cerebral microvascular endothelial cells injury induced by hypoxia and reoxygenation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080301
Voltammetric Behavior of o-Nitrophenol and Damage to DNA. International journal of molecular sciences 20080301
Baicalin inhibits macrophage activation by lipopolysaccharide and protects mice from endotoxin shock. Biochemical pharmacology 20080215
Protective effects of baicalin and octreotide on multiple organ injury in severe acute pancreatitis. Digestive diseases and sciences 20080201
Protective effects of baicalin on ligature-induced periodontitis in rats. Journal of periodontal research 20080201
[Studies on change of chemical composition in coptis-scute herb couple by using HPCE and HPLC]. Yao xue xue bao = Acta pharmaceutica Sinica 20080201
Protective effect of baicalin against carbon tetrachloride-induced acute hepatic injury in mice. Journal of pharmacological sciences 20080101
Validation of a HPLC method for flavonoid biomarkers in skullcap (Scutellaria) and its use to illustrate wide variability in the quality of commercial tinctures. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20080101
Therapeutic effects of baicalin on lipopolysaccharide-induced acute lung injury in rats. The American journal of Chinese medicine 20080101
The overall quality control of Radix scutellariae by capillary electrophoresis fingerprint. Journal of chromatographic science 20080101
Inhibitory effects of Baicalin on ultraviolet B-induced photo-damage in keratinocyte cell line. The American journal of Chinese medicine 20080101
Preparation of high-purity baicalein from Scutellaria baicalensis Georgi. Natural product research 20080101
Apoptosis induced by baicalin involving up-regulation of P53 and bax in MCF-7 cells. Journal of Asian natural products research 20080101
Effects of baicalin and wogonin on mucin release from cultured airway epithelial cells. Phytotherapy research : PTR 20071201
In-vivo and in-vitro studies on the effect of Huang-Lian-Jie-Du-Tang on nimodipine transport across rat blood-brain barrier. The Journal of pharmacy and pharmacology 20071201
Flavonoid accumulation in Scutellaria baicalensis Georgii in vitro cultures upon treatment with sodium cinnamate. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20071201
[Pharmacokinetic study on baicalin of Qingkailing injection in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201
[Fast and simultaneous determination of four index components in Qingwei Huanglian tablets by RP-HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201
Baicalein induces cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and AKT. Molecular cancer therapeutics 20071101
[Protective effect of baicalin on mouse with Parkinson's disease induced by MPTP]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20071101
[Effect of baicalin on in vivo anti-virus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071101
[Anaerobic biodegradation pathway of the main ingredient of traditional Chinese medicine wastewater]. Huan jing ke xue= Huanjing kexue 20071101
[Experimental studies on compound Duzhong Jiangya prescription by semi-bionic extraction]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071101
Simultaneous determination of safflor yellow A, puerarin, daidzein, ginsenosides (Rg(1), Rb(1), Rd), and notoginsenoside R(1) in rat plasma by liquid chromatography-mass spectrometry. Journal of pharmaceutical and biomedical analysis 20071018
Protective effects and mechanisms of Baicalin and octreotide on renal injury of rats with severe acute pancreatitis. World journal of gastroenterology 20071014
[An experimental research on differentiation of mesenchymal stem cells derived from children with spinal muscular atrophy into neuron-like cells]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20071001
[Advances in the studies of Oroxylum indicum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071001
[Studies on effect of microemulsion in enhancing solubility of baicalin and puerarin]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071001
[Simultaneous determination of baicalin and chlorogenic acid in human plasma by UPLC-MS/MS]. Yao xue xue bao = Acta pharmaceutica Sinica 20071001
Diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles. Journal of the American Chemical Society 20070926
A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. Journal of medicinal food 20070901
[Study on skin toxicology and penetration enhancement of skin absorption of volatile oil extracted from tender branchers of Camellia oleifera]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901
Hypouricemic action of selected flavonoids in mice: structure-activity relationships. Biological & pharmaceutical bulletin 20070801
[Processing method and HPLC fingerprint of charred radix Scutellariae]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801
[HPLC fingerprint of flavonoids of Kushen Tang and its correlation to Scutellaria baicalensis and Sophora flavescens]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801
[Effects of processing and extracting methods on active components in Radix Scutellariae by HPLC analysis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801
San-Huang-Xie-Xin-Tang inhibits Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells. Journal of ethnopharmacology 20070725
Comparative effects of flavonoids on oxidant scavenging and ischemia-reperfusion injury in cardiomyocytes. European journal of pharmacology 20070702
Surface modification of three-dimensional poly(d,l-lactic acid) scaffolds with baicalin: a histological study. Acta biomaterialia 20070701
Simultaneous determination of trans-resveratrol-3-O-glucoside and its two metabolites in rat plasma using liquid chromatography with ultraviolet detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070701
Baicalein inhibition of hydrogen peroxide-induced apoptosis via ROS-dependent heme oxygenase 1 gene expression. Biochimica et biophysica acta 20070701
Orthogonal array design for the optimization of supercritical fluid extraction of baicalin from roots of Scutellaria baicalensis Georgi. Journal of separation science 20070701
Baicalin reduces the severity of experimental autoimmune encephalomyelitis. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070701
[Pharmacokinetics of flavonoids from xiexin decoction in rats]. Yao xue xue bao = Acta pharmaceutica Sinica 20070701
[Simultaneous determination of geniposide, baicalin and berberine hydrochloride in Angong Niuhuang pill by RP-HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070701
Baicalin protects mouse from Concanavalin A-induced liver injury through inhibition of cytokine production and hepatocyte apoptosis. Liver international : official journal of the International Association for the Study of the Liver 20070501
Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats. Journal of ethnopharmacology 20070404
Scutellaria baicalensis, a herbal medicine: anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines. Leukemia research 20070401
Effect of baicalin and berberine on transport of nimodipine on primary-cultured, rat brain microvascular endothelial cells. Acta pharmacologica Sinica 20070401
[Effects of baicalin and other Chinese herbal monomer on androgen receptor mRNA expression in SZ95 sebocytes]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20070401
[Study on anti-endotoxin of baicalin]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20070401
[Effects of N P K on yield and baicalin contents of Scutellaria baicalensis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070401
The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke. Neuropharmacology 20070301
[The optimum condition on baicalin extraction from Scutellaria baicalensis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070301
Experimental study of therapeutic efficacy of Baicalin in rats with severe acute pancreatitis. World journal of gastroenterology 20070207
Baicalin attenuates oxygen-glucose deprivation-induced injury via inhibiting NMDA receptor-mediated 5-lipoxygenase activation in rat cortical neurons. Pharmacological research 20070201
Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract of Scutellaria baicalensis, PF-2405 in rats. Archives of pharmacal research 20070201
[Protective action of effective components of Huanglian Jiedu decoction on hypoxia and reoxygenation injury in cultured rat cerebral microvascular endothelial cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070201
[The effect of cyrstal water on determining content of baicalin]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070201
Inhibitory effect of flavonoid baicalin on degranulation of human polymorphonuclear leukocytes induced by interleukin-8: potential role in periodontal diseases. Journal of ethnopharmacology 20070119
Quantitative analysis and chromatographic fingerprinting for the quality evaluation of Scutellaria baicalensis Georgi using capillary electrophoresis. Journal of pharmaceutical and biomedical analysis 20070117
Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell. Cancer letters 20070108
Simultaneous determination of eight active components in Chinese medicine 'YIQING' capsule using high-performance liquid chromatography. Journal of pharmaceutical and biomedical analysis 20070104
Gradient high-performance liquid chromatography for the simultaneous determination of chlorogenic acid and baicalin in plasma and its application in the study of pharmacokinetics in rats. Journal of pharmaceutical and biomedical analysis 20070104
Determination of dopamine and its relativity of baicalin in rat nuclei after intravenous administration of flavonoids from Scutellariae radix. Biomedical chromatography : BMC 20070101
Efflux of baicalin, a flavone glucuronide of Scutellariae Radix, on Caco-2 cells through multidrug resistance-associated protein 2. The Journal of pharmacy and pharmacology 20070101
ROS mediates baicalin-induced apoptosis in human promyelocytic leukemia HL-60 cells through the expression of the Gadd153 and mitochondrial-dependent pathway. Anticancer research 20070101
[Simultaneous analysis of six effective components in the anti-Alzheimer's disease effective component group of Xiao-Xu-Ming Decoction]. Se pu = Chinese journal of chromatography 20070101
A survey of Chinese herbal ingredients with liver protection activities. Chinese medicine 20070101
[Studies on chemical components of Cirsium segestum]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070101
Polygonum cuspidatum, compared with baicalin and berberine, inhibits inducible nitric oxide synthase and cyclooxygenase-2 gene expressions in RAW 264.7 macrophages. Vascular pharmacology 20070101
Reduction of urate crystal-induced inflammation by root extracts from traditional oriental medicinal plants: elevation of prostaglandin D2 levels. Arthritis research & therapy 20070101
[Antiatherosclerotic properties of flavones from the roots of Scutellaria baicalensis Georgi]. Wiadomosci lekarskie (Warsaw, Poland : 1960) 20070101
Baicalein inhibits IL-1beta- and TNF-alpha-induced inflammatory cytokine production from human mast cells via regulation of the NF-kappaB pathway. Clinical and molecular allergy : CMA 20070101
The protecting effects and mechanisms of Baicalin and Octreotide on heart injury in rats with SAP. Mediators of inflammation 20070101
Saikokeishito Extract Exerts a Therapeutic Effect on alpha-Naphthylisothiocyanate-Induced Liver Injury in Rats through Attenuation of Enhanced Neutrophil Infiltration and Oxidative Stress in the Liver Tissue. Journal of clinical biochemistry and nutrition 20070101
Wogonin suppresses TNF-alpha-induced MMP-9 expression by blocking the NF-kappaB activation via MAPK signaling pathways in human aortic smooth muscle cells. Biochemical and biophysical research communications 20061208
A comparative study on the individual and combined effects of baicalin and jasminoidin on focal cerebral ischemia-reperfusion injury. Brain research 20061206
Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061205
Baicalein inhibition of oxidative-stress-induced apoptosis via modulation of ERKs activation and induction of HO-1 gene expression in rat glioma cells C6. Toxicology and applied pharmacology 20061015
Analysis of baicalein, baicalin and wogonin in Scutellariae radix and its preparation by microemulsion electrokinetic chromatography with 1-butyl-3-methylimizolium tetrafluoborate ionic liquid as additive. Journal of chromatography. A 20061006
Optimal antidiarrhea treatment for antitumor agent irinotecan hydrochloride (CPT-11)-induced delayed diarrhea. Cancer chemotherapy and pharmacology 20061001
Determination of human plasma protein binding of baicalin by ultrafiltration and high-performance liquid chromatography. Biomedical chromatography : BMC 20061001
[Determination of 3 kinds of components in huanglian jiedu decoction by HPLC under different UV wavelengths]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061001
Simultaneous determination of geniposide, baicalin, cholic acid and hyodeoxycholic acid in rat serum for the pharmacokinetic investigations by high performance liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060914
Short-term feeding of baicalin inhibits age-associated NF-kappaB activation. Mechanisms of ageing and development 20060901
The antipyretic effects of baicalin in lipopolysaccharide-evoked fever in rabbits. Neuropharmacology 20060901
Pharmacological properties of traditional medicine (XXXII): protective effects of hangeshashinto and the combinations of its major constituents on gastric lesions in rats. Biological & pharmaceutical bulletin 20060901
[Pharmacokinetic study of cancer chemotherapy]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060901
Simultaneous analysis of nine active components in Gegen Qinlian preparations by high-performance liquid chromatography with diode array detection. Journal of separation science 20060901
[Research on different processings of Scutellaria baicalensis Georgi]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060901
Synergistic effect of a novel oxymatrine-baicalin combination against hepatitis B virus replication, alpha smooth muscle actin expression and type I collagen synthesis in vitro. World journal of gastroenterology 20060828
[Inhibition of extracts from 17 Chinese herbs on periodontal pathogenic microbes]. Shanghai kou qiang yi xue = Shanghai journal of stomatology 20060801
Retention behavior of silica-bonded and novel polymeric reversed-phase sorbents in studies on flavones as chemotaxonomic markers of Scutellaria L. genus. Journal of chromatography. A 20060707
[Effect of baicalin on HSP70 expression of hippocampal neurons in focal brain ischemia-reperfusion injury rats]. Yao xue xue bao = Acta pharmaceutica Sinica 20060701
[Study on quality control and fingerprint of Chinese traditional medicine Yinhuang oral liquid]. Se pu = Chinese journal of chromatography 20060701
Simultaneous determination of baicalin, rhein and berberine in rat plasma by column-switching high-performance liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060621
Development of the chromatographic fingerprint of herbal preparations Shuang-Huang-Lian oral liquid. Journal of pharmaceutical and biomedical analysis 20060607
Investigation of the absorption mechanisms of baicalin and baicalein in rats. Journal of pharmaceutical sciences 20060601
[Protective effects of baicalin pretreatment on hypoxic-ischemic brain damage in neonatal rats]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20060601
[Effect of baicalin on expression of heme oxygenase-1 in lung injury of rats associated with paraquat poisoning]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20060601
[Effect of some active Chinese herbal fraction on brain tissue proteomic profile of ischemic mouse]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060601
[Pharmacological evaluation of baicalin and jasminoidin and their combination on focal cerebral ischemia-reperfusion injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060601
[Studies on the absorption kinetics of baicalin and baicalein in rats' stomachs and intestines]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060601
Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 2. Current oncology (Toronto, Ont.) 20060601
[Simultaneous determination of four compounds in Sanjing Shuanghuanglian Oral Liquid by high performance liquid chromatography-diode array detection-electrochemical detection]. Se pu = Chinese journal of chromatography 20060501
Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury. European journal of pharmacology 20060424
High-performance liquid chromatographic method for simultaneous quantification of eight major biologically active ingredients in 'Da-Chai-Hu-Tang' preparation. Biomedical chromatography : BMC 20060401
Effects of Scutellaria baicalensis Georgi on macrophage-hepatocyte interaction through cytokines related to growth control of murine hepatocytes. Experimental biology and medicine (Maywood, N.J.) 20060401
[Study on molecular mechanism of inhibitory effect of baicalin on proliferation of insulinoma cell line in rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060401
[Qualitative and quantitative determination of the main components of huanglianjiedu decoction by HPLC-UV/MS]. Yao xue xue bao = Acta pharmaceutica Sinica 20060401
Dietary supplementation of baicalin and quercetin attenuates iron overload induced mouse liver injury. European journal of pharmacology 20060327
Simultaneous determination of nine components in Qingkailing injection by HPLC/ELSD/DAD and its application to the quality control. Journal of pharmaceutical and biomedical analysis 20060303
HPLC with electrochemical detection to examine the pharmacokinetics of baicalin and baicalein in rat plasma after oral administration of a Kampo medicine. Analytical biochemistry 20060301
Analysis of the interactions of botanical extract combinations against the viability of prostate cancer cell lines. Evidence-based complementary and alternative medicine : eCAM 20060301
[Differentiation of human umbilical cord blood mesenchymal stem cells toward neurons induced by baicalin in vitro]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20060301
[The content condition of effective composition in Sanhuang Xiexin decoction]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060301
[Simultaneous determination of three kinds of components in sanhuang tablets by high-performance liquid chromatography]. Yao xue xue bao = Acta pharmaceutica Sinica 20060301
Control release effects of binders used in pills of traditional Chinese medicine herbs. Chemical & pharmaceutical bulletin 20060201
Anxiolytic-Like Effect of baicalin and its additivity with other anxiolytics. Planta medica 20060201
Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 1. Current oncology (Toronto, Ont.) 20060201
Kinetic difference of baicalin in rat blood and cerebral nuclei after intravenous administration of Scutellariae Radix extract. Journal of ethnopharmacology 20060103
Sensitive liquid chromatography-tandem mass spectrometry method for the determination of scutellarin in human plasma: Application to a pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060102
Application of LC/MS and ICP/MS for establishing the fingerprint spectrum of the traditional Chinese medicinal preparation Gan-Lu-Yin. Journal of separation science 20060101
[Determination of contents of the effective ingredients in root of Scutellaria baicalensis by HPLC-ECD]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060101
[Pharmacokinetics study on yinhuang compound microenema in rabbits]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060101
Baicalin-induced apoptosis is mediated by Bcl-2-dependent, but not p53-dependent, pathway in human leukemia cell lines. The American journal of Chinese medicine 20060101
Influence of baicalin on the expression of receptor activator of nuclear factor-kappaB ligand in cultured human periodontal ligament cells. Pharmacology 20060101
Cardioprotective effects of grape seed proanthocyanidins, baicalin and wogonin: comparison between acute and chronic treatments. The American journal of Chinese medicine 20060101
Differential inhibitory effects of baicalein and baicalin on LPS-induced cyclooxygenase-2 expression through inhibition of C/EBPbeta DNA-binding activity. Immunobiology 20060101
Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells. BMC complementary and alternative medicine 20060101
Simultaneous quantification of twelve bioactive components in San-huang-xie-xin-tang by HPLC. Phytochemical analysis : PCA 20060101
Antoxid increases ferric reducing antioxidant power (FRAP) even stronger than vitamin C. Acta poloniae pharmaceutica 20060101
Adjusting effects of baicalin for nuclear factor-kappaB and tumor necrosis factor-alpha on rats with caerulein-induced acute pancreatitis. Mediators of inflammation 20060101
Human cytomegalovirus-inhibitory flavonoids: studies on antiviral activity and mechanism of action. Antiviral research 20051201
Cytoprotective mechanism of baicalin against endothelial cell damage by peroxynitrite. The Journal of pharmacy and pharmacology 20051201
Absorption and enterohepatic circulation of baicalin in rats. Life sciences 20051126
Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an 'in vitro' replicative system. Antiviral research 20051101
Simultaneous determination of major bioactive components in Qingkailing injection by high-performance liquid chromatography with evaporative light scattering detection. Chemical & pharmaceutical bulletin 20051101
Antiherpetic activities of flavonoids against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) in vitro. Archives of pharmacal research 20051101
[Study on the collecting method of constituents absorbed into the blood from anti-V capsule]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051101
[Study on the metabolism of the precipitation of Xiexin decoction in rats I]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051101
Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin. Biochimica et biophysica acta 20051010
San-Huang-Xie-Xin-Tang attenuates inflammatory responses in lipopolysaccharide-exposed rat lungs. Journal of ethnopharmacology 20051003
Stability of baicalin in biological fluids in vitro. Journal of pharmaceutical and biomedical analysis 20050915
A chromatographic method for baicalin quantification in rat thalamus. Biomedical chromatography : BMC 20050901
[Simultaneous determination of five groups of components in qingkailing injection by high performance liquid chromatography with photo diode array detector and evaporative light scattering detector]. Se pu = Chinese journal of chromatography 20050901
Comparison of the metabolism of baicalin in rats orally administered with Radix scutellariae extract and Shuang-Huang-Lian extract. Chemical & pharmaceutical bulletin 20050801
Protective effects of baicalin on oxygen/glucose deprivation- and NMDA-induced injuries in rat hippocampal slices. The Journal of pharmacy and pharmacology 20050801
[Study on preparation technological process of huangqin qingfei koufuye]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050801
5-Lipoxygenase inhibitors attenuate growth of human renal cell carcinoma and induce apoptosis through arachidonic acid pathway. Oncology reports 20050701
Role of intestinal first-pass metabolism of baicalein in its absorption process. Pharmaceutical research 20050701
Regulation of IGF-I production and proliferation of human leiomyomal smooth muscle cells by Scutellaria barbata D. Don in vitro: isolation of flavonoids of apigenin and luteolin as acting compounds. Toxicology and applied pharmacology 20050615
Ultrasound-assisted extraction methodology as a tool to improve the antioxidant properties of herbal drug Xiao-chia-hu-tang. Journal of ethnopharmacology 20050603
Interaction of baicalin and baicalein with antibiotics in the gastrointestinal tract. The Journal of pharmacy and pharmacology 20050601
Uptake of irinotecan metabolite SN-38 by the human intestinal cell line Caco-2. Cancer chemotherapy and pharmacology 20050501
Enhancing effects of Scutellaria baicalensis and some of its constituents on TGF-beta1 gene expression in RAW 264.7 murine macrophage cell line. Planta medica 20050501
Evaluation of in vitro effects of natural substances of plant origin using a model of protein glycoxidation. Journal of pharmaceutical and biomedical analysis 20050429
Baicalein, a component of Scutellaria radix from Huang-Lian-Jie-Du-Tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells. Blood 20050415
Biological properties of baicalein in cardiovascular system. Current drug targets. Cardiovascular & haematological disorders 20050401
[Effect of baicalin on the proliferation of insulinoma cell line]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20050401
[Study on yield and quality of Scutellaria baicalensis from different habitats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050401
Gene expression profile induced by oral administration of baicalin and gardenin after focal brain ischemia in rats. Acta pharmacologica Sinica 20050301
[Effect of nuclear factor-kappaB on differentiation of bone marrow stromal cells into neurons induced by baicalin in rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050301
Separation and purification of baicalin and wogonoside from the Chinese medicinal plant Scutellaria baicalensis Georgi by high-speed counter-current chromatography. Journal of chromatography. A 20050225
Effects of dietary baicalin supplementation on iron overload-induced mouse liver oxidative injury. European journal of pharmacology 20050221
Protective effect of baicalin on tert-butyl hydroperoxide-induced rat hepatotoxicity. Archives of toxicology 20050201
In vitro studies of baicalin alone or in combination with Salvia miltiorrhiza extract as a potential anti-cancer agent. International journal of oncology 20050101
In vivo and in vitro effect of baicalein on human prostate cancer cells. International journal of oncology 20050101
Baicalein protects rat cardiomyocytes from hypoxia/reoxygenation damage via a prooxidant mechanism. Cardiovascular research 20050101
[Determination of baicalin in Xiaoyanling Decoction by high-performance liquid chromatography]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20050101
[Study of baicalin in inducing prostate cancer cell line DU145 apoptosis in vitro]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050101
Melatonin, a potent agent in antioxidative defense: actions as a natural food constituent, gastrointestinal factor, drug and prodrug. Nutrition & metabolism 20050101
Separation and isolation methods for analysis of the active principles of Sho-saiko-to (SST) oriental medicine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041205
Separation methods used for Scutellaria baicalensis active components. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041205
Baicalin induces NAD(P)H:quinone reductase through the transactivation of AP-1 and NF-kappaB in Hepa 1c1c7 cells. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20041201
High-performance liquid chromatographic method for simultaneous determination of baicalein and baicalein 7-glucuronide in rat plasma. Journal of pharmaceutical and biomedical analysis 20041115
Zinc coupling potentiates anti-HIV-1 activity of baicalin. Biochemical and biophysical research communications 20041112
A metabolomic analysis of medicinal diversity in Huang-qin (Scutellaria baicalensis Georgi) genotypes: discovery of novel compounds. Plant cell reports 20041101
Pharmacokinetics of baicalin in rats and its interactions with cyclosporin A, quinidine and SKF-525A: a microdialysis study. Planta medica 20041101
Enteric excretion of baicalein, a flavone of Scutellariae Radix, via glucuronidation in rat: involvement of multidrug resistance-associated protein 2. Pharmaceutical research 20041101
Study on the precipitation reaction between baicalin and berberine by HPLC. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041015
Metabolic activities of ginsenoside Rb1, baicalin, glycyrrhizin and geniposide to their bioactive compounds by human intestinal microflora. Biological & pharmaceutical bulletin 20041001
Pharmacological properties of traditional medicine (XXIX): effect of Hange-shashin-to and the combinations of its herbal constituents on rat experimental colitis. Biological & pharmaceutical bulletin 20041001
In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20040901
Dietary polyphenols (-)-epicatechin and chrysin inhibit intestinal glucuronidation metabolism to increase drug absorption. Journal of pharmaceutical sciences 20040901
Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships. Molecular pharmacology 20040901
[Isolation and elucidation of antioxidant constituents from acetone extract in root of Scutellaria rehderiana]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040901
[Experimental study on prevention and treatment of bronchial asthma by compound Chinese herbal monomer recipe]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040801
[Azoic color reaction of flavonoids and their analytical application]. Guang pu xue yu guang pu fen xi = Guang pu 20040801
Potent Inhibitory effect of flavonoids in Scutellaria baicalensis on amyloid beta protein-induced neurotoxicity. Journal of agricultural and food chemistry 20040630
The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils. The Journal of biological chemistry 20040625
Determination of rhein, baicalin and berberine in traditional Chinese medicinal preparations by capillary electrophoresis with two-marker technique. Biomedical chromatography : BMC 20040601
Electrochemical investigations of baicalin and DNA-baicalin interactions. Analytical and bioanalytical chemistry 20040501
Effects of Sho-saiko-to extract and its components, Baicalin, baicalein, glycyrrhizin and glycyrrhetic acid, on pharmacokinetic behavior of salicylamide in carbon tetrachloride intoxicated rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040501
[Effects of baicalin on the expression of pro-MMP-1 and MMP-3 in human gingival fibroblasts and periodontal ligament cells]. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20040501
[Effects of effective component from 'qing kai ling' on endothelial cell of microvessel in MCAO rats]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040501
[Antagonistic effect of baicalin on oxidative stress injury in neurons and astrocytes of rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040401
Inhibitory effects of Scutellaria barbata D. Don on human uterine leiomyomal smooth muscle cell proliferation through cell cycle analysis. International immunopharmacology 20040301
Inhibition of nitric oxide/cyclic GMP-mediated relaxation by purified flavonoids, baicalin and baicalein, in rat aortic rings. Biochemical pharmacology 20040215
Significant decrease of cyclosporine bioavailability in rats caused by a decoction of the roots of Scutellaria baicalensis. Planta medica 20040201
Antimutagenic and antiradical properties of flavones from the roots of Scutellaria baicalensis georgi. Die Nahrung 20040201
Flavonoids from Radix Scutellariae as potential stroke therapeutic agents by targeting the second postsynaptic density 95 (PSD-95)/disc large/zonula occludens-1 (PDZ) domain of PSD-95. Phytomedicine : international journal of phytotherapy and phytopharmacology 20040101
In vitro antileukemic, antioxidant and prooxidant activities of Antoksyd S (C/E/XXI): a comparison with baicalin and baicalein. In vivo (Athens, Greece) 20040101
Proteomic analysis of mouse liver for the evaluation of effects of Scutellariae radix by liquid chromatography with tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20040101
Quality evaluation of commercial extracts of Scutellaria baicalensis. Nutrition and cancer 20040101
A new approach to investigate the pharmacokinetics of traditional chinese medicine YL2000. The American journal of Chinese medicine 20040101
[The effect of Baicalin on gene expression profile in rat brain of focal cerebral ischemia]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040101
[Study on subcritical water extraction of baicalin from Radix Scutellariae coupled to high performance liquid chromatographic analysis]. Se pu = Chinese journal of chromatography 20040101
[Simultaneous determination of berberin hydrochloride, baicalin and glibenclamide in kangtang tablets by RP-HPLC]. Se pu = Chinese journal of chromatography 20040101
Baicalin induces differential expression of cytochrome C oxidase in human lung H441 cell. Journal of agricultural and food chemistry 20031203
The antiinflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia. Anesthesia and analgesia 20031201
Hepatoprotective effect of baicalin, a major flavone from Scutellaria radix, on acetaminophen-induced liver injury in mice. Immunopharmacology and immunotoxicology 20031101
Phytochemical and biological analysis of skullcap (Scutellaria lateriflora L.): a medicinal plant with anxiolytic properties. Phytomedicine : international journal of phytotherapy and phytopharmacology 20031101
Application of high-speed counter-current chromatography to the preparative separation and purification of baicalin from the Chinese medicinal plant Scutellaria baicalensis. Journal of chromatography. A 20031031
Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death. Brain research 20031003
Baicalein and baicalin are potent inhibitors of angiogenesis: Inhibition of endothelial cell proliferation, migration and differentiation. International journal of cancer 20030910
HPLC analyses and pharmacokinetic studies of baicalin and oxymatrine in rabbits. Die Pharmazie 20030901
Antioxidant status and mineral contents in tissues of rutin and baicalin fed rats. Life sciences 20030808
Effects of baicalin, baicalein, and wogonin on interleukin-6 and interleukin-8 expression, and nuclear factor-kappab binding activities induced by interleukin-1beta in human retinal pigment epithelial cell line. Experimental eye research 20030801
Pharmacokinetic study on the multi-constituents of Huangqin-Tang decoction in rats. Biological & pharmaceutical bulletin 20030701
Immunomodulatory activities of flavonoids, monoterpenoids, triterpenoids, iridoid glycosides and phenolic compounds of Plantago species. Planta medica 20030701
Main flavonoids in the root of Scutellaria baicalensis cultivated in Europe and their comparative antiradical properties. Phytotherapy research : PTR 20030601
Determination of amino acid neurotransmitters in cerebral cortex of rats administered with baicalin prior to cerebral ischemia by capillary electrophoresis-laser-induced fluorescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505
Preventive effect of Kampo medicine (Hangeshashin-to) against irinotecan-induced diarrhea in advanced non-small-cell lung cancer. Cancer chemotherapy and pharmacology 20030501
Effects of baicalin on the gene expression of surfactant protein A (SP-A) in lung adenocarcinoma cell line H441. Planta medica 20030401
Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora. Journal of natural products 20030401
Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes. European journal of pharmacology 20030328
Anxiolytic-like effects of baicalein and baicalin in the Vogel conflict test in mice. European journal of pharmacology 20030319
[The study of characteristics of absorption and separation of different glycoside on macropore resins]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030301
Baicalin promoted the repair of DNA single strand breakage caused by H2O2 in cultured NIH3T3 fibroblasts. Biological & pharmaceutical bulletin 20030201
Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats. The Journal of pharmacy and pharmacology 20030201
Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of Scutellariae Radix in humans. Biological & pharmaceutical bulletin 20030101
Effects of topical instillation of traditional herbal medicines, herbal extracts, and their components on prostaglandin E2-induced aqueous flare elevation in pigmented rabbits. Japanese journal of ophthalmology 20030101
Assessment of the antibacterial activity of selected flavonoids and consideration of discrepancies between previous reports. Microbiological research 20030101
Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies. Journal of natural products 20021201
[Effects of Azone of different concentrations on percutaneous absorption of baicalin in vitro]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021101
[Differentiation of rat bone marrow stromal cells into neuron induced by baicalin]. Zhonghua yi xue za zhi 20021010
Herbal composition PC-SPES for management of prostate cancer: identification of active principles. Journal of the National Cancer Institute 20020904
[Combination use of kampo-medicines and drugs affecting intestinal bacterial flora]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020901
PC-SPES: herbal formulation for prostate cancer. Urology 20020901
Baicalin-induced vascular response in rat mesenteric artery: role of endothelial nitric oxide. Clinical and experimental pharmacology & physiology 20020801
[A novel approach to quality evaluation of root of Scutellaria baicalensis by DPPH free radical scavenging]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20020801
Antiviral activity of Plantago major extracts and related compounds in vitro. Antiviral research 20020701
Structure-activity relationship of natural flavonoids in hydroxyl radical-scavenging effects. Acta pharmacologica Sinica 20020701
Evaluation of variation of acteoside and three major flavonoids in wild and cultivated Scutellaria baicalensis roots by micellar electrokinetic chromatography. Chemical & pharmaceutical bulletin 20020701
[Effects of baicalin on contents of PGE2 and cAMP in hypothalamus of fever rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20020501
[Study of protective effect and mechanism for baicalin on bacillus pertussis infected brain tissue and its dose-effect relationship]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020401
[Measurement of baicalin contents by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20020401
Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice. Planta medica 20020301
[Determination of flavone for Scutellaria baicalensis from different areas by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20020301
Antiviral Chinese medicinal herbs against respiratory syncytial virus. Journal of ethnopharmacology 20020201
Baicalin induces apoptosis via mitochondrial pathway as prooxidant. Molecular immunology 20020201
Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines. Planta medica 20020201
Induction of apoptosis in human lung fibroblasts and peripheral lymphocytes in vitro by Shosaiko-to derived phenolic metabolites. Biological & pharmaceutical bulletin 20020101
Comparative study of the high molecular mass fraction and low molecular mass fraction of Sho-saiko-to in a murine immunologically induced liver injury model. Biological & pharmaceutical bulletin 20020101
Activity of drugs from traditional Chinese medicine toward sensitive and MDR1- or MRP1-overexpressing multidrug-resistant human CCRF-CEM leukemia cells. Blood cells, molecules & diseases 20020101
Anticancer, antiradical and antioxidative actions of novel Antoksyd S and its major components, baicalin and baicalein. Anticancer research 20020101
The potential for an interaction between MRP2 (ABCC2) and various therapeutic agents: probenecid as a candidate inhibitor of the biliary excretion of irinotecan metabolites. Drug metabolism and pharmacokinetics 20020101
Baicalin is a major component of PC-SPES which inhibits the proliferation of human cancer cells via apoptosis and cell cycle arrest. The Prostate 20011201
[Study on effect of qingkailing injection and its active principle in inducing cell apoptosis in human acute promyelocytic leukemia]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20011101
[Studies on metabolites of baicalin in human urine]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20011101
Effects of the flavonoid baicalin and its metabolite baicalein on androgen receptor expression, cell cycle progression and apoptosis of prostate cancer cell lines. Cell proliferation 20011001
Identification and determination of glucuronides and their aglycones in Erigeron breviscapus by liquid chromatography-tandem mass spectrometry. Journal of chromatography. A 20010914
In vitro mechanism of PC SPES. Urology 20010801
Antifibrogenic therapies in chronic HCV infection. Current drug targets. Infectious disorders 20010801
Chemiluminescence flow sensor for berberine with immobilized reagents. Bioorganic & medicinal chemistry 20010701
The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines. FEBS letters 20010629
3D-QSAR model of flavonoids binding at benzodiazepine site in GABAA receptors. Journal of medicinal chemistry 20010607
Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide. Biochemical pharmacology 20010601
Determination of 14 chemical constituents in the traditional Chinese medicinal preparation Huangqin-Tang by high performance liquid chromatography. Biological & pharmaceutical bulletin 20010601
[Determination of forsythin, chlorogenic acid and baicalin in jieduxuantou decoction by RP-HPLC]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20010401
Inhibitory effect of baicalein, a flavonoid in Scutellaria Root, on eotaxin production by human dermal fibroblasts. Planta medica 20010301
[Study on the preparation of baicalin complex with phospholipid]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010301
Protective effects of flavonoids in the roots of Scutellaria baicalensis Georgi against hydrogen peroxide-induced oxidative stress in HS-SY5Y cells. Pharmacological research 20010201
[Effects of baicalin on hepatocyte apoptosis induced by TNF-alpha and act D in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010201
Anti-HIV activity of medicinal herbs: usage and potential development. The American journal of Chinese medicine 20010101
Effects of scutellariae radix extract and its components (baicalein, baicalin, and wogonin) on the experimental elevation of aqueous flare in pigmented rabbits. Japanese journal of ophthalmology 20010101
Anti-hepatitis B virus effects of wogonin isolated from Scutellaria baicalensis. Planta medica 20001201
Flavonoid baicalin inhibits HIV-1 infection at the level of viral entry. Biochemical and biophysical research communications 20000924
Baicalin, an inhibitor of HIV-1 production in vitro. Antiviral research 19980201
[Synthesis of baicalin derivatives and evaluation of their anti-human immunodeficiency virus (HIV-1) activity]. Yao xue xue bao = Acta pharmaceutica Sinica 19980101
Sho-saiko-to, a traditional Kampo medicine, enhances the anti-HIV-1 activity of lamivudine (3TC) in vitro. Microbiology and immunology 19970101
Inhibition of HIV activation in latently infected cells by flavonoid compounds. AIDS research and human retroviruses 19960101
Anti-AIDS agents, 10. Acacetin-7-O-beta-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids. Journal of natural products 19940101
Inhibition of HIV infection by baicalin--a flavonoid compound purified from Chinese herbal medicine. Cellular & molecular biology research 19930101
Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases. European journal of biochemistry 19900705
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