(1S,2S,3R,5S)-3-(7-(((1R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3h-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
| Title | Journal |
|---|---|
| Critical Role of P2Y(12) Receptor in Regulation of Th17 Differentiation and Experimental Autoimmune Encephalomyelitis Pathogenesis. | Journal of immunology (Baltimore, Md. : 1950) 20170701 |
| A semi-quantitative translational pharmacology analysis to understand the relationship between in vitro ENT1 inhibition and the clinical incidence of dyspnoea and bronchospasm. | Toxicology and applied pharmacology 20170215 |
| Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12 -receptor. | Journal of thrombosis and haemostasis : JTH 20141101 |
| Characterization of the adenosine pharmacology of ticagrelor reveals therapeutically relevant inhibition of equilibrative nucleoside transporter 1. | Journal of cardiovascular pharmacology and therapeutics 20140301 |
| Lead optimization of ethyl 6-aminonicotinate acyl sulfonamides as antagonists of the P2Y12 receptor. separation of the antithrombotic effect and bleeding for candidate drug AZD1283. | Journal of medicinal chemistry 20130912 |
| Lack of clinically significant pharmacological interactions between ticagrelor and enoxaparin or unfractionated heparin in healthy subjects. | Journal of clinical pharmacy and therapeutics 20121201 |
| The evolution of antiplatelet therapy in the treatment of acute coronary syndromes: from aspirin to the present day. | Drugs 20121112 |
| Safety profile and bleeding risk of ticagrelor compared with clopidogrel. | Expert opinion on drug safety 20121101 |
| [Platelet inhibitors in clinical practice]. | Therapeutische Umschau. Revue therapeutique 20121101 |
| Identification of high-affinity P2Y₁₂ antagonists based on a phenylpyrazole glutamic acid piperazine backbone. | Journal of medicinal chemistry 20121025 |
| Factors contributing to the lower mortality with ticagrelor compared with clopidogrel in patients undergoing coronary artery bypass surgery. | Journal of the American College of Cardiology 20121023 |
| Antiplatelet therapy for patients with diabetes mellitus and acute coronary syndrome. | Primary care diabetes 20121001 |
| Current antiplatelet options for NSTE-ACS patients. | QJM : monthly journal of the Association of Physicians 20121001 |
| Improving long-term ACS management: is there a role for the new antiplatelets? | Journal of interventional cardiology 20121001 |
| Acute ST-elevation myocardial infarction. | Current opinion in critical care 20121001 |
| Evaluation of ticagrelor pharmacodynamic interactions with reversibly binding or non-reversibly binding P2Y(12) antagonists in an ex-vivo canine model. | Thrombosis research 20121001 |
| Review of ticagrelor in the management of acute coronary syndromes. | Expert opinion on drug metabolism & toxicology 20121001 |
| New anti-platelet agents: the end of resistance? | Thrombosis research 20121001 |
| Ticagrelor (brilinta), an antiplatelet drug for acute coronary syndrome. | P & T : a peer-reviewed journal for formulary management 20121001 |
| Letter by Fort and Plachetka regarding article, 'association of proton pump inhibitor use on cardiovascular outcomes with clopidogrel and ticagrelor: insights from PLATO'. | Circulation 20120911 |
| Pharmacokinetics, pharmacodynamics, and safety of ticagrelor in volunteers with severe renal impairment. | Journal of clinical pharmacology 20120901 |
| Platelets in atherothrombosis--diagnostic and prognostic value of platelet activation in patients with atherosclerotic diseases. | Current vascular pharmacology 20120901 |
| Platelet hyperreactivity and stent thrombosis in patients undergoing coronary stenting. | Current vascular pharmacology 20120901 |
| P2Y(12) receptors in platelets and other hematopoietic and non-hematopoietic cells. | Purinergic signalling 20120901 |
| Novel antiplatelet therapy in acute coronary syndromes: what is new in the pipeline? | Current vascular pharmacology 20120901 |
| Antiplatelet therapy: Treatment with ticagrelor for 12 months after ACS is cost-effective. | Nature reviews. Cardiology 20120901 |
| Updating an institutional chest pain algorithm: incorporating new evidence on emerging pharmacotherapy. | Critical pathways in cardiology 20120901 |
| Viewpoint: Central adjudication of myocardial infarction in outcome-driven clinical trials--common patterns in TRITON, RECORD, and PLATO? | Thrombosis and haemostasis 20120901 |
| UA/NSTEMI: Are you following the latest guidelines? | Nursing 20120901 |
| Prior smoking status, clinical outcomes, and the comparison of ticagrelor with clopidogrel in acute coronary syndromes-insights from the PLATelet inhibition and patient Outcomes (PLATO) trial. | American heart journal 20120901 |
| Ticagrelor: molecular discovery to clinical evidence: ticagrelor: a novel antiplatelet agent. | Indian heart journal 20120901 |
| [Medication of the month. Ticagrelor (Brilique): potent oral antagonist of platelet activity]. | Revue medicale de Liege 20120901 |
| Novel platelet ADP P2Y12 inhibitors in the treatment of acute coronary syndrome. | Cardiovascular therapeutics 20120801 |
| Lack of significant food effect on the pharmacokinetics of ticagrelor in healthy volunteers. | Journal of clinical pharmacy and therapeutics 20120801 |
| Effect of age and gender on pharmacokinetics and pharmacodynamics of a single ticagrelor dose in healthy individuals. | European journal of clinical pharmacology 20120801 |
| Which antiplatelet agent for whom? Which patient populations benefit most from novel antiplatelet agents (ticagrelor, prasugrel)? | Current cardiology reports 20120801 |
| Platelet function and inhibition in ischemic heart disease. | Current cardiology reports 20120801 |
| Network meta-analysis of prasugrel, ticagrelor, high- and standard-dose clopidogrel in patients scheduled for percutaneous coronary interventions. | Thrombosis and haemostasis 20120801 |
| Ticagrelor in clopidogrel-resistant patients undergoing maintenance hemodialysis. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20120801 |
| Clinical pharmacogenomics of warfarin and clopidogrel. | Journal of pharmacy practice 20120801 |
| Ticagrelor versus prasugrel in acute coronary syndrome patients with high on-clopidogrel platelet reactivity following percutaneous coronary intervention: a pharmacodynamic study. | Journal of the American College of Cardiology 20120717 |
| Quantitative comparison of clopidogrel 600 mg, prasugrel and ticagrelor, against clopidogrel 300 mg on major adverse cardiovascular events and bleeding in coronary stenting: synthesis of CURRENT-OASIS-7, TRITON-TIMI-38 and PLATO. | International journal of cardiology 20120712 |
| Baseline Q waves as a prognostic modulator in patients with ST-segment elevation: insights from the PLATO trial. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20120710 |
| Ticagrelor, but not clopidogrel and prasugrel, prevents ADP-induced vascular smooth muscle cell contraction: a placebo-controlled study in rats. | Thrombosis research 20120701 |
| Prasugrel during primary percutaneous coronary intervention: evidence from clinical data. | Current vascular pharmacology 20120701 |
| Ticagrelor in ST-elevation myocardial infarction. | Current vascular pharmacology 20120701 |
| Advances in antiplatelet therapy for acute coronary syndromes. | Postgraduate medical journal 20120701 |
| Lessons from platelet inhibition and patient outcomes. | Current opinion in cardiology 20120701 |
| Comparative pharmacokinetics and pharmacodynamics of platelet adenosine diphosphate receptor antagonists and their clinical implications. | Clinical pharmacokinetics 20120701 |
| Farnesyl pyrophosphate is an endogenous antagonist to ADP-stimulated P2Y₁₂ receptor-mediated platelet aggregation. | Thrombosis and haemostasis 20120701 |
| New drugs 2012, part 2. | Nursing 20120701 |
| Usefulness of the VerifyNow P2Y12 assay to evaluate the antiplatelet effects of ticagrelor and clopidogrel therapies. | American heart journal 20120701 |
| Atopaxar: a review of its mechanism of action and role in patients with coronary artery disease. | Future cardiology 20120701 |
| Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack. | Circulation 20120612 |
| Beware of novel antiplatelet therapy in acute coronary syndrome patients with previous stroke. | Circulation 20120612 |
| Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model. | Journal of cardiovascular pharmacology and therapeutics 20120601 |
| Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: results from the ONSET-OFFSET and RESPOND studies. | Clinical pharmacokinetics 20120601 |
| Ticagrelor: oral reversible P2Y(12) receptor antagonist for the management of acute coronary syndromes. | Clinical therapeutics 20120601 |
| Synthesis and biological evaluation of ticagrelor derivatives as novel antiplatelet agents. | Bioorganic & medicinal chemistry letters 20120601 |
| Management of non-ST-segment elevation acute coronary syndrome: comparison of the updated guidelines from North America and Europe. | Critical pathways in cardiology 20120601 |
| Use of cilostazol in percutaneous coronary interventions. | The Annals of pharmacotherapy 20120601 |
| Meeting new challenges with antiplatelet therapy in primary care. | The Journal of family practice 20120601 |
| [Platelet function: new drugs, new assays : possible impacts on operative medicine?]. | Der Anaesthesist 20120601 |
| Unstable angina and non-ST elevation myocardial infarction. | American journal of respiratory and critical care medicine 20120501 |
| Pharmacokinetic, pharmacodynamic and pharmacogenetic profile of the oral antiplatelet agent ticagrelor. | Clinical pharmacokinetics 20120501 |
| Personalised antiplatelet therapy in stent thrombosis: observations from the Clopidogrel Resistance in Stent Thrombosis (CREST) registry. | Heart (British Cardiac Society) 20120501 |
| Ticagrelor: a P2Y12 antagonist for use in acute coronary syndromes. | Expert review of clinical pharmacology 20120501 |
| Mechanisms of Platelet Activation and Integrin αIIβ3. | Korean circulation journal 20120501 |
| Cardiac dysfunction in the CABG patient. | Current opinion in pharmacology 20120401 |
| [Modern treatment in acute coronary syndrome]. | Deutsche medizinische Wochenschrift (1946) 20120401 |
| Latest evidence in personalized antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary intervention. | Hospital practice (1995) 20120401 |
| Ticagrelor: a new option for ACS. | The Nurse practitioner 20120313 |
| Antiplatelet therapy: controversial aspects. | Thrombosis research 20120301 |
| [New antiplatelet agents and the question of dual antiplatelet therapy]. | Der Internist 20120301 |
| Review of atrial fibrillation outcome trials of oral anticoagulant and antiplatelet agents. | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20120301 |
| Emerging antiplatelet therapy for coronary artery disease and acute coronary syndrome. | Pharmacotherapy 20120301 |
| Peripheral vascular outcomes in the PLATO trial: update from the FDA ticagrelor complete response review. | American journal of therapeutics 20120301 |
| Association of proton pump inhibitor use on cardiovascular outcomes with clopidogrel and ticagrelor: insights from the platelet inhibition and patient outcomes trial. | Circulation 20120227 |
| Ticagrelor induces adenosine triphosphate release from human red blood cells. | Biochemical and biophysical research communications 20120224 |
| Optimizing antiplatelet therapy in acute coronary syndrome and percutaneous coronary intervention. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120201 |
| Antiplatelet and anticoagulant drugs in interventional radiology. | Cardiovascular and interventional radiology 20120201 |
| Antiplatelet function variability in clopidogrel-treated patients: need for new antiplatelet agents. | Fundamental & clinical pharmacology 20120201 |
| Clinical effects and outcomes with new P2Y12 inhibitors in ACS. | Fundamental & clinical pharmacology 20120201 |
| In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization. | Purinergic signalling 20120201 |
| Novel antiplatelet therapies. | Current atherosclerosis reports 20120201 |
| Pharmacokinetics and tolerability of single and multiple doses of ticagrelor in healthy Chinese subjects: an open-label, sequential, two-cohort, single-centre study. | Clinical drug investigation 20120201 |
| Antiplatelet therapy in patients with ST-elevation myocardial infarction undergoing myocardial revascularisation: beyond clopidogrel. | Current medical research and opinion 20120201 |
| P2Y12 platelet inhibition in clinical practice. | Journal of thrombosis and thrombolysis 20120201 |
| Optimal management of antiplatelet therapy and proton pump inhibition following percutaneous coronary intervention. | Current treatment options in cardiovascular medicine 20120201 |
| Management of coagulation: an Australian perspective. | Current opinion in anaesthesiology 20120201 |
| Evaluation and characterization of the effects of ticagrelor on serum and urinary uric acid in healthy volunteers. | Clinical pharmacology and therapeutics 20120201 |
| A comprehensive comparative review of adenosine diphosphate receptor antagonists. | Expert opinion on pharmacotherapy 20120201 |
| InforMatrix: ADP antagonists in acute coronary syndromes. | Expert opinion on pharmacotherapy 20120201 |
| Effect size of ticagrelor over clopidogrel in the Platelet Inhibition and Patient Outcomes (PLATO) trial: from statistics to clinical judgment. | Journal of cardiovascular medicine (Hagerstown, Md.) 20120201 |
| 'Conversations in cardiology': How do you pick the best antiplatelet drug--clopidogrel, prasugrel, ticagrelor for your PCI patient? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120201 |
| Primary and secondary prevention of cardiovascular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. | Chest 20120201 |
| ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial: insights from the ECG substudy. | Circulation 20120124 |
| No one-size-fits-all: A tailored approach to antithrombotic therapy after stent implantation. | Circulation 20120124 |
| Do aspirin and other antiplatelet drugs reduce the mortality in critically ill patients? | Thrombosis 20120101 |
| Cystatin C and estimated glomerular filtration rate as predictors for adverse outcome in patients with ST-elevation and non-ST-elevation acute coronary syndromes: results from the Platelet Inhibition and Patient Outcomes study. | Clinical chemistry 20120101 |
| Antiplatelet therapy in acute coronary syndromes. | Expert opinion on pharmacotherapy 20120101 |
| Recent advances in epidural analgesia. | Anesthesiology research and practice 20120101 |
| Bleeding tendency in dual antiplatelet therapy with aspirin/clopidogrel: rescue of the template bleeding time in a single-center prospective study. | Thrombosis journal 20120101 |
| Antiplatelet therapy in atherothrombotic cardiovascular diseases for primary and secondary prevention: a focus on old and new antiplatelet agents. | Current pharmaceutical design 20120101 |
| Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology. | Frontiers in pharmacology 20120101 |
| New perspectives in antiplatelet therapy. | Current medicinal chemistry 20120101 |
| Increased atherothrombotic burden in patients with diabetes mellitus and acute coronary syndrome: a review of antiplatelet therapy. | Cardiology research and practice 20120101 |
| A critical appraisal of the functional evolution of P2Y12 antagonists as antiplatelet drugs. | Current pharmaceutical design 20120101 |
| Evolving role of platelet function testing in coronary artery interventions. | Vascular health and risk management 20120101 |
| Who protects physicians and patients from guidelines? | Cardiology 20120101 |
| Serotonin antagonism improves platelet inhibition in clopidogrel low-responders after coronary stent placement: an in vitro pilot study. | PloS one 20120101 |
| Oral antiplatelet therapy for atherothrombotic disease: overview of current and emerging treatment options. | Vascular health and risk management 20120101 |
| [Optimal antiplatelet and antithrombotic therapy in patients with ST elevation myocardial infarction]. | Kardiologia polska 20120101 |
| [Letter to Kardiologia Polska concerning optimal treatment of myocardial infarction]. | Kardiologia polska 20120101 |
| The avantgarde carbostent in patients scheduled for undelayable noncardiac surgery. | Thrombosis 20120101 |
| Chinese herb and formulas for promoting blood circulation and removing blood stasis and antiplatelet therapies. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| The 'Harmonizing Optimal Strategy for Treatment of coronary artery stenosis - sAfety & effectiveneSS of drug-elUting stents & antiplatelet REgimen' (HOST-ASSURE) trial: study protocol for a randomized controlled trial. | Trials 20120101 |
| Platelet adenosine diphosphate receptor antagonists: ticlopidine to ticagrelor-a long continuing journey. | Indian heart journal 20120101 |
| Anticoagulant and antiplatelet therapy in patients with atrial fibrillation and coronary artery disease. | Thrombosis 20120101 |
| Stent thrombosis: incidence, predictors and new technologies. | Thrombosis 20120101 |
| Do Clopidogrel Nonresponders Have an Increased Risk of Adverse Events during Supra-Aortal Angioplasty and Stenting? | Stroke research and treatment 20120101 |
| [New antithrombotic drugs]. | Duodecim; laaketieteellinen aikakauskirja 20120101 |
| Dabigatran for stroke prevention in nonvalvular atrial fibrillation: answers to challenging 'real-world' questions. | Thrombosis 20120101 |
| Dual thienopyridine low-response to clopidogrel and prasugrel in a patient with STEMI, cardiogenic shock and early stent thrombosis is overcome by ticagrelor. | Platelets 20120101 |
| Antiplatelet therapy - ticagrelor. | Hamostaseologie 20120101 |
| Ticagrelor FDA approval issues revisited. | Cardiology 20120101 |
| [The role of direct-acting P2Y12 inhibitors in acute coronary syndrome]. | Kardiologiia 20120101 |
| Impact of antiplatelet therapy in heart disease. | Advances in cardiology 20120101 |
| Clopidogrel in coronary artery disease: update 2012. | Advances in cardiology 20120101 |
| Antiplatelet therapy in acute coronary syndromes: ticagrelor. | Advances in cardiology 20120101 |
| Genetic considerations. | Advances in cardiology 20120101 |
| Advances in the monitoring of anti-P2Y12 therapy. | Platelets 20120101 |
| Thienopyridines and other ADP-receptor antagonists. | Handbook of experimental pharmacology 20120101 |
| Intracellular signaling as a potential target for antiplatelet therapy. | Handbook of experimental pharmacology 20120101 |
| Antiplatelet therapy in peripheral artery disease. | Handbook of experimental pharmacology 20120101 |
| Antiplatelet agents and anticoagulants for hypertension. | The Cochrane database of systematic reviews 20111207 |
| Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes. | European heart journal 20111201 |
| Clopidogrel resistance: identifying and overcoming a barrier to effective antiplatelet treatment. | Cardiovascular therapeutics 20111201 |
| Pulmonary function in patients with acute coronary syndrome treated with ticagrelor or clopidogrel (from the Platelet Inhibition and Patient Outcomes [PLATO] pulmonary function substudy). | The American journal of cardiology 20111201 |
| Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y₁₂ antagonist ticagrelor. | Thrombosis and haemostasis 20111201 |
| Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial. | European heart journal 20111201 |
| No free lunches: balancing bleeding and efficacy with ticagrelor. | European heart journal 20111201 |
| Unravelling the benefit against the risk of long-term dual antiplatelet therapy. | Current opinion in cardiology 20111201 |
| [Who protects physicians and patients from guidelines?]. | Deutsche medizinische Wochenschrift (1946) 20111201 |
| Recent advances in the management of acute myocardial infarction. | The Journal of the Association of Physicians of India 20111201 |
| Safety and efficacy of antiplatelet and antithrombotic therapy in acute coronary syndrome patients with chronic kidney disease. | Journal of the American College of Cardiology 20111122 |
| Genetic determinants of platelet response to clopidogrel. | Journal of thrombosis and thrombolysis 20111101 |
| Role of platelet function testing in clinical practice: current concepts and future perspectives. | Current drug targets 20111101 |
| Overcoming limitations of current antiplatelet drugs: a concerted effort for more profitable strategies of intervention. | Annals of medicine 20111101 |
| Current concepts on coronary revascularization in diabetic patients. | European heart journal 20111101 |
| Treating acute coronary syndromes with new antiplatelet drugs: the mortality issue with prasugrel and ticagrelor. | Current medical research and opinion 20111101 |
| Female platelets are hard to control. | Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20111101 |
| Antiplatelet options for secondary prevention in acute coronary syndromes. | Expert review of cardiovascular therapy 20111101 |
| Evaluating the risk-benefit profile of the direct-acting P2Y(12) inhibitor ticagrelor in acute coronary syndromes. | Postgraduate medicine 20111101 |
| [New era in antiplatelet therapy based on results from recent clinical trials]. | Medicina clinica 20111022 |
| Oral antiplatelet agents in ACS: from pharmacology to clinical differences. | Fundamental & clinical pharmacology 20111001 |
| Anti-platelet therapy: ADP receptor antagonists. | British journal of clinical pharmacology 20111001 |
| Genotypic and phenotypic assessment of platelet function and response to P2Y12 antagonists. | Current cardiology reports 20111001 |
| Antiplatelet effects of aspirin vary with level of P2Y₁₂ receptor blockade supplied by either ticagrelor or prasugrel. | Journal of thrombosis and haemostasis : JTH 20111001 |
| Vorapaxar: a novel protease-activated receptor-1 inhibitor. | Expert opinion on investigational drugs 20111001 |
| Clopidogrel discontinuation after acute coronary syndromes: frequency, predictors and associations with death and myocardial infarction--a hospital registry-primary care linked cohort (MINAP-GPRD). | European heart journal 20111001 |
| Use of prasugrel in a patient with clopidogrel hypersensitivity. | The Annals of pharmacotherapy 20111001 |
| Variability of clopidogrel response in patients with type 2 diabetes mellitus. | Diabetes & vascular disease research 20111001 |
| Ticagrelor. Acute coronary syndromes: nothing new. | Prescrire international 20111001 |
| Benefits of ticagrelor debated as antiplatelet class approaches generic market. | Managed care (Langhorne, Pa.) 20111001 |
| Managing adverse effects and drug-drug interactions of antiplatelet agents. | Nature reviews. Cardiology 20110913 |
| Ticagrelor (Brilinta)--better than clopidogrel (Plavix)? | The Medical letter on drugs and therapeutics 20110905 |
| Implications of variability in definition and reporting of major bleeding in randomized trials of oral P2Y12 inhibitors for acute coronary syndromes. | European heart journal 20110901 |
| Disposition and metabolism of ticagrelor, a novel P2Y12 receptor antagonist, in mice, rats, and marmosets. | Drug metabolism and disposition: the biological fate of chemicals 20110901 |
| Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses. | Journal of thrombosis and haemostasis : JTH 20110901 |
| Agreement between adjusted indirect comparison and simplified network meta-analyses on prasugrel and ticagrelor (Reply to Passaro et al. - Int J Cardiol 2011). | International journal of cardiology 20110901 |
| P2 receptors and platelet function. | Purinergic signalling 20110901 |
| P2Y₁₂ receptor inhibitors: integrating ticagrelor into the management of acute coronary syndrome. | The Annals of pharmacotherapy 20110901 |
| Ticagrelor approved for acute coronary syndrome. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110901 |
| Evaluation of the effect of dapagliflozin on cardiac repolarization: a thorough QT/QTc study. | Diabetes therapy : research, treatment and education of diabetes and related disorders 20110901 |
| Adjusted indirect comparison meta-analysis of prasugrel versus ticagrelor for patients with acute coronary syndromes. | International journal of cardiology 20110804 |
| Anti-platelet treatments in acute coronary syndrome: simplified network meta-analysis. | International journal of cardiology 20110804 |
| Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial. | Circulation 20110802 |
| P2Y12 antagonists in acute coronary syndrome: in whom should they be started, and when? | Current cardiology reports 20110801 |
| High platelet reactivity and clinical outcome - fact and fiction. | Thrombosis and haemostasis 20110801 |
| Antithrombotic management for transient ischemic attack and ischemic stroke (other than atrial fibrillation). | Current atherosclerosis reports 20110801 |
| Beyond aspirin and clopidogrel: is there a need for additional antiplatelet therapy in ACS? | Current cardiology reports 20110801 |
| Effect of ticagrelor on the pharmacokinetics of ethinyl oestradiol and levonorgestrel in healthy volunteers. | Current medical research and opinion 20110801 |
| Determination of unbound ticagrelor and its active metabolite (AR-C124910XX) in human plasma by equilibrium dialysis and LC-MS/MS. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110801 |
| Prasugrel vs. ticagrelor in acute coronary syndromes: which one to choose? | Wiener klinische Wochenschrift 20110801 |
| The future of platelet function testing to guide therapy in clopidogrel low and enhanced responders. | Expert review of cardiovascular therapy 20110801 |
| Impact of dyspnea on medical utilization and affiliated costs in patients with acute coronary syndrome. | Hospital practice (1995) 20110801 |
| Pharmacokinetics, pharmacodynamics, and safety of ticagrelor in volunteers with mild hepatic impairment. | Journal of clinical pharmacology 20110701 |
| Ischaemic and bleeding complications with new, compared to standard, ADP-antagonist regimens in acute coronary syndromes: a meta-analysis of randomized trials. | QJM : monthly journal of the Association of Physicians 20110701 |
| The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies. | American heart journal 20110701 |
| [Ticagrelor: a novel antiplatelet agent for patients with acute coronary syndrome]. | Medizinische Monatsschrift fur Pharmazeuten 20110701 |
| Non-interventional management of acute coronary syndromes. | BMJ (Clinical research ed.) 20110617 |
| How to explain the reduced cardiovascular mortality in the ticagrelor arm of the PLATO trial? | International journal of cardiology 20110602 |
| Novel antiplatelet agent ticagrelor in the management of acute coronary syndrome. | Journal of interventional cardiology 20110601 |
| Beyond efficacy: pharmacokinetic differences between clopidogrel, prasugrel and ticagrelor. | Expert opinion on pharmacotherapy 20110601 |
| Usefulness of a nanoparticle formulation to investigate some hemodynamic parameters of a poorly soluble compound. | Journal of pharmaceutical sciences 20110601 |
| [Myocardial infarction: Role of new antiplatelet agents]. | Presse medicale (Paris, France : 1983) 20110601 |
| [Update on anti-platelet therapy]. | Deutsche medizinische Wochenschrift (1946) 20110601 |
| Ticagrelor for acute coronary syndrome? | Drug and therapeutics bulletin 20110601 |
| Ticagrelor versus genotype-driven antiplatelet therapy for secondary prevention after acute coronary syndrome: a cost-effectiveness analysis. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110601 |
| The incidence of bradyarrhythmias and clinical bradyarrhythmic events in patients with acute coronary syndromes treated with ticagrelor or clopidogrel in the PLATO (Platelet Inhibition and Patient Outcomes) trial: results of the continuous electrocardiographic assessment substudy. | Journal of the American College of Cardiology 20110510 |
| Ticagrelor: a review of its use in the management of acute coronary syndromes. | Drugs 20110507 |
| [New approaches and indications for the analysis of platelet function in cardiology]. | Hamostaseologie 20110502 |
| Viewpoint: paradoxical excess mortality in the PLATO trial should be independently verified. | Thrombosis and haemostasis 20110501 |
| Explaining the unexpected: insights from the PLATelet inhibition and clinical Outcomes (PLATO) trial comparing ticagrelor and clopidogrel. Editorial on Serebruany 'Viewpoint: Paradoxical excess mortality in the PLATO trial should be independently verified' (Thromb Haemost 2011; 105.5). | Thrombosis and haemostasis 20110501 |
| The PLATO trial reveals further opportunities to improve outcomes in patients with acute coronary syndrome. Editorial on Serebruany. 'Viewpoint: Paradoxical excess mortality in the PLATO trial should be independently verified' (Thromb Haemost 2011; 105.5). | Thrombosis and haemostasis 20110501 |
| Bleeding manifestations of congenital and drug-induced defects of the platelet P2Y12 receptor for adenosine diphosphate. | Thrombosis and haemostasis 20110501 |
| Pharmacology and clinical trials of reversibly-binding P2Y12 inhibitors. | Thrombosis and haemostasis 20110501 |
| [Coronary stent thrombosis: what's new in 2011?]. | Herz 20110501 |
| Advances in cardiology: clinical trial update. | Future cardiology 20110501 |
| In vitro evaluation of potential drug-drug interactions with ticagrelor: cytochrome P450 reaction phenotyping, inhibition, induction, and differential kinetics. | Drug metabolism and disposition: the biological fate of chemicals 20110401 |
| Fresh from the pipeline. Ticagrelor. | Nature reviews. Drug discovery 20110401 |
| [Do genetic factors reduce the effects of clopidogrel?]. | Deutsche medizinische Wochenschrift (1946) 20110401 |
| [Recent advances on the studies of the platelet's inhibition and aggregation. State of the art of new P2Y12 antagonists]. | Recenti progressi in medicina 20110401 |
| Oral antiplatelet therapy for atherothrombotic disease: current evidence and new directions. | American heart journal 20110301 |
| The platelet P2Y₁₂ receptor for adenosine diphosphate: congenital and drug-induced defects. | Blood 20110217 |
| Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery: results from the PLATO (Platelet Inhibition and Patient Outcomes) trial. | Journal of the American College of Cardiology 20110208 |
| Mechanisms potentially contributing to the reduction in mortality associated with ticagrelor therapy. | Journal of the American College of Cardiology 20110208 |
| Allergic reactions to clopidogrel and cross-reactivity to other agents. | Current allergy and asthma reports 20110201 |
| Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist. | Arteriosclerosis, thrombosis, and vascular biology 20110201 |
| Succinate independently stimulates full platelet activation via cAMP and phosphoinositide 3-kinase-β signaling. | Journal of thrombosis and haemostasis : JTH 20110201 |
| Antiplatelet drugs: a review of their pharmacology and management in the perioperative period. | Anesthesia and analgesia 20110201 |
| Antithrombotic therapy in ST-segment elevation myocardial infarction. | Expert opinion on pharmacotherapy 20110201 |
| Overview of the 2010 Food and Drug Administration Cardiovascular and Renal Drugs Advisory Committee meeting regarding ticagrelor. | Circulation 20110201 |
| Resistance to anti-platelet agents. | Thrombosis research 20110201 |
| [Coronary heart disease - what is of importance after coronary intervention?]. | Deutsche medizinische Wochenschrift (1946) 20110201 |
| Ticagrelor: from concept to clinical evaluation. | Biomarkers in medicine 20110201 |
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