Home Aminos Adenosine,3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-, dihydrochloride

Adenosine,3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-, dihydrochloride

CAS No.:
58-58-2
Catalog Number:
AG00IABE
Molecular Formula:
C22H31Cl2N7O5
Molecular Weight:
544.4314
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
≥98%
1 week
United States
$97
- +
50mg
≥98%
1 week
United States
$125
- +
100mg
≥98%
1 week
United States
$179
- +
500mg
≥98%
1 week
United States
$540
- +
Product Description
Catalog Number:
AG00IABE
Chemical Name:
Adenosine,3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-, dihydrochloride
CAS Number:
58-58-2
Molecular Formula:
C22H31Cl2N7O5
Molecular Weight:
544.4314
MDL Number:
MFCD00012691
IUPAC Name:
(2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide;dihydrochloride
InChI:
InChI=1S/C22H29N7O5.2ClH/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12;;/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32);2*1H/t14-,15+,16+,18+,22+;;/m0../s1
InChI Key:
MKSVFGKWZLUTTO-FZFAUISWSA-N
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1NC(=O)[C@H](Cc1ccc(cc1)OC)N)O)n1cnc2c1ncnc2N(C)C.Cl.Cl
EC Number:
200-387-8
UNII:
PGN54228S5
Properties
Complexity:
680  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
5  
Defined Bond Stereocenter Count:
0
Exact Mass:
543.176g/mol
Formal Charge:
0
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0
Molecular Weight:
544.434g/mol
Monoisotopic Mass:
543.176g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
161A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
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The pur7 gene from the puromycin biosynthetic pur cluster of Streptomyces alboniger encodes a nudix hydrolase. Journal of bacteriology 19990801
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Alterations in the distribution of plasma fibronectin and the ultrastructure of podocytes in the peripheral glomerular loops in nephrotic rats. Virchows Archiv : an international journal of pathology 19981101
The Pur10 protein encoded in the gene cluster for puromycin biosynthesis of Streptomyces alboniger is an NAD-dependent ATP dehydrogenase. FEBS letters 19981023
Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis. The American journal of pathology 19971001
Dual effects of lisinopril on puromycin aminonucleoside nephrosis in unilaterally nephrectomized rats. Japanese journal of pharmacology 19970401
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Gene expression of hepatic cholesterol 7 alpha-hydroxylase in the course of puromycin-induced nephrosis. Kidney international 19960301
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Limitations of podocyte adaptation for glomerular injury in puromycin aminonucleoside nephrosis. Pathology international 19950901
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Superinduction of 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible expression of aldehyde dehydrogenase by the inhibition of protein synthesis. Biochemical and biophysical research communications 19911031
In vitro effects of puromycin aminonucleoside on the ultrastructure of rat glomerular podocytes. Cell and tissue research 19900501
Enalapril and low protein reverse chronic puromycin aminonucleoside nephropathy. Kidney international 19900201
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Evidence suggesting a role for hydroxyl radical in puromycin aminonucleoside-induced proteinuria. Kidney international 19881001
Glomerular basement membrane heparan sulfate glycosaminoglycan in aminonucleoside of puromycin nephrosis. Child nephrology and urology 19880101
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Failure of angiotensin converting enzyme inhibition to affect the course of chronic puromycin aminonucleoside nephropathy. The American journal of pathology 19871101
The enhancement of aminonucleoside nephrosis by the co-administration of protamine. Kidney international 19871101
Urinalysis for detection of chemically induced renal damage (2)--Changes in urinary excretions of enzymes and various components caused by p-aminophenol, puromycin aminonucleoside and hexadimethrine. The Journal of toxicological sciences 19871101
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Ameliorative effects of dietary protein restriction in chronic aminonucleoside nephrosis. The Journal of laboratory and clinical medicine 19870501
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Effects of saikosaponin-d on aminonucleoside nephrosis in rats. European journal of pharmacology 19860121
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Chryscandin, a novel peptidyl nucleoside antibiotic. I. Taxonomy, fermentation, isolation and characterization. The Journal of antibiotics 19841101
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The effect of protamine on proteinuria and glomerular sclerosis in aminonucleoside nephropathy. The Tohoku journal of experimental medicine 19820401
Indication for central vagal endorphinergic control of heart rate in dogs. European journal of pharmacology 19810522
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Biochemical studies of the isolated rat glomerulus and the effects of puromycin aminonucleoside administration. British journal of experimental pathology 19800201
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Control of differentiation in streptomycetes: involvement of extrachromosomal deoxyribonucleic acid and glucose repression in aerial mycelia development. Journal of bacteriology 19760201
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A comparison of the effects of lipolytic and antilipolytic agents on adenosine 3',5'-monophosphate levels in adipose cells as determined by prior labeling with adenine-8-14C. The Journal of biological chemistry 19690510
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