Home Aminos 2,5-Diaminotoluene diHCl

2,5-Diaminotoluene diHCl

CAS No.:
615-45-2
Catalog Number:
AG00IAVN
Molecular Formula:
C7H12Cl2N2
Molecular Weight:
195.0896
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25g
>98.0%(T)(HPLC)
1 week
United States
$178
- +
Product Description
Catalog Number:
AG00IAVN
Chemical Name:
2,5-Diaminotoluene diHCl
CAS Number:
615-45-2
Molecular Formula:
C7H12Cl2N2
Molecular Weight:
195.0896
MDL Number:
MFCD00035512
IUPAC Name:
2-methylbenzene-1,4-diamine;dihydrochloride
InChI:
InChI=1S/C7H10N2.2ClH/c1-5-4-6(8)2-3-7(5)9;;/h2-4H,8-9H2,1H3;2*1H
InChI Key:
VQUHVWVGRKTIBH-UHFFFAOYSA-N
SMILES:
Nc1ccc(c(c1)C)N.Cl.Cl
UNII:
GY506235UT
Properties
Complexity:
92.9  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
194.038g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
195.087g/mol
Monoisotopic Mass:
194.038g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
52A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
p-Phenylenediamine and other hair dye sensitizers in Spain. Contact dermatitis 20120101
Internal exposure of hairdressers to permanent hair dyes: a biomonitoring study using urinary aromatic diamines as biomarkers of exposure. International archives of occupational and environmental health 20110301
Determination of 2,5-toluylenediamine (2,5-TDA) and aromatic amines in urine after personal application of hair dyes: kinetics and doses. Archives of toxicology 20110201
The hair dyes PPD and PTD fail to induce a T(H)2 immune response following repeated topical application in BALB/c mice. Journal of immunotoxicology 20110101
Alternative hair-dye products for persons allergic to para-phenylenediamine. Dermatitis : contact, atopic, occupational, drug 20110101
Para-phenylenediamine-specific lymphocyte activation test: a sensitive in vitro assay to detect para-phenylenediamine sensitization in patients with severe allergic reactions. Experimental dermatology 20100501
Final amended report of the safety assessment of toluene-2,5-diamine, toluene-2,5-diamine sulfate, and toluene-3,4-diamine as used in cosmetics. International journal of toxicology 20100501
Severe inflammatory and keloidal, allergic reaction due to para-phenylenediamine in temporary tattoos. Indian journal of dermatology, venereology and leprology 20100101
Potent skin sensitizers in oxidative hair dye products on the Swedish market. Contact dermatitis 20091101
Cross-reactions among hair dye allergens. Cutaneous and ocular toxicology 20090101
Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances. Contact dermatitis 20081001
Primary sensitization to toluene-2,5-diamine giving rise to early positive patch reaction to p-phenylenediamine and late to toluene-2,5-diamine. Contact dermatitis 20080901
Toluene-2,5-diamine may be an isolated allergy in individuals sensitized by permanent hair dye. Contact dermatitis 20070901
Allergic contact dermatitis from toluene-2,5-diamine in a cream dye for eyelashes and eyebrows--quantitative exposure assessment. Contact dermatitis 20070901
Hair dye contact allergy: quantitative exposure assessment of selected products and clinical cases. Contact dermatitis 20040601
Hair dye-sensitized hairdressers: the cross-reaction pattern with new generation hair dyes. Contact dermatitis 20020601
Interaction with the aromatic hydrocarbon receptor, CYP1A induction, and mutagenicity of a series of diaminotoluenes: implications for their carcinogenicity. Toxicology and applied pharmacology 19960701
Properties