Home Carboxys (2S)-5-oxopyrrolidine-2-carboxylic acid

(2S)-5-oxopyrrolidine-2-carboxylic acid

CAS No.:
98-79-3
Catalog Number:
AG00IK0B
Molecular Formula:
C5H7NO3
Molecular Weight:
129.1140
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$13
- +
25g
98%
In Stock USA
United States
$19
- +
100g
95%
In Stock USA
United States
$47
- +
250g
95%
In Stock USA
United States
$75
- +
Product Description
Catalog Number:
AG00IK0B
Chemical Name:
(2S)-5-oxopyrrolidine-2-carboxylic acid
CAS Number:
98-79-3
Molecular Formula:
C5H7NO3
Molecular Weight:
129.1140
MDL Number:
MFCD00005272
IUPAC Name:
(2S)-5-oxopyrrolidine-2-carboxylic acid
InChI:
InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1
InChI Key:
ODHCTXKNWHHXJC-VKHMYHEASA-N
SMILES:
O=C1CCC(N1)C(=O)O
EC Number:
202-700-3
Properties
Complexity:
154  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
129.043g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
129.115g/mol
Monoisotopic Mass:
129.043g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
66.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.8  
Literature
Title Journal
The adipokinetic hormone of the coleopteran suborder Adephaga: Structure, function, and comparison of distribution in other insects. Archives of insect biochemistry and physiology 20170701
The dental monomer hydroxyethyl methacrylate (HEMA) counteracts lipopolysaccharide-induced IL-1β release-Possible role of glutathione. Toxicology letters 20170315
The adipokinetic hormone of Mantodea in comparison to other Dictyoptera. Archives of insect biochemistry and physiology 20170301
Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis. PloS one 20170101
Promising toxicological biomarkers for the diagnosis of liver injury types: Bile acid metabolic profiles and oxidative stress marker as screening tools in drug development. Chemico-biological interactions 20160805
Benzyl butyl phthalate promotes adipogenesis in 3T3-L1 preadipocytes: A High Content Cellomics and metabolomic analysis. Toxicology in vitro : an international journal published in association with BIBRA 20160401
Actions of Bisphenol A and Bisphenol S on the Reproductive Neuroendocrine System During Early Development in Zebrafish. Endocrinology 20160201
Filaggrin deficiency leads to impaired lipid profile and altered acidification pathways in a 3D skin construct. The Journal of investigative dermatology 20140301
Integrated systems toxicology approaches identified the possible involvement of ABC transporters pathway in erythromycin estolate-induced liver injury in rat. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140301
Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures. PloS one 20140101
Five functional adipokinetic peptides expressed in the corpus cardiacum of the moth genus Hippotion (Lepidoptera, Sphingidae). Regulatory peptides 20130610
Novel adipokinetic hormones in the kissing bugs Rhodnius prolixus, Triatoma infestans, Dipetalogaster maxima and Panstrongylus megistus. Peptides 20130301
Modulation of airway epithelial cell functions by Pidotimod: NF-kB cytoplasmatic expression and its nuclear translocation are associated with an increased TLR-2 expression. Italian journal of pediatrics 20130101
Comprehensive impurity profiling of nutritional infusion solutions by multidimensional off-line reversed-phase liquid chromatography × hydrophilic interaction chromatography-ion trap mass-spectrometry and charged aerosol detection with universal calibration. Journal of chromatography. A 20121012
Efficient production and characterization of the sweet-tasting brazzein secreted by the yeast Pichia pastoris. Journal of agricultural and food chemistry 20121003
Energy-dependent modulation of glucagon-like signaling in Drosophila via the AMP-activated protein kinase. Genetics 20121001
Crystal structures of glutaminyl cyclases (QCs) from Drosophila melanogaster reveal active site conservation between insect and mammalian QCs. Biochemistry 20120918
Composition and antimicrobial activity of fatty acids detected in the hygroscopic secretion collected from the secretory setae of larvae of the biting midge Forcipomyia nigra (Diptera: Ceratopogonidae). Journal of insect physiology 20120901
Food-restricted and dehydrated-induced anorexic rats present differential TRH expression in anterior and caudal PVN. Role of type 2 deiodinase and pyroglutamyl aminopeptidase II. Endocrinology 20120801
A mathematical modelling approach to assessing the reliability of biomarkers of glutathione metabolism. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120716
Plant growth stimulation in Prunus species plantlets by BTH or OTC treatments under in vitro conditions. Journal of plant physiology 20120715
Recombinant production of isotope-labeled peptides and spontaneous cyclization of amino-terminal glutamine into pyroglutamic acid. Chembiochem : a European journal of chemical biology 20120709
5-oxoprolinemia causing elevated anion gap metabolic acidosis in the setting of acetaminophen use. The Journal of emergency medicine 20120701
Pyroglutamyl peptidase II inhibition enhances the analeptic effect of thyrotropin-releasing hormone in the rat medial septum. The Journal of pharmacology and experimental therapeutics 20120701
Structure-activity studies of Drosophila adipokinetic hormone (AKH) by a cellular expression system of dipteran AKH receptors. General and comparative endocrinology 20120701
N-Terminal pyroglutamate formation of Aβ38 and Aβ40 enforces oligomer formation and potency to disrupt hippocampal long-term potentiation. Journal of neurochemistry 20120601
GnRH-III based multifunctional drug delivery systems containing daunorubicin and methotrexate. European journal of medicinal chemistry 20120601
Molecular imaging of dementia. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society 20120601
Anti-fibrotic effects of L-2-oxothiazolidine-4-carboxylic acid via modulation of nuclear factor erythroid 2-related factor 2 in rats. BMB reports 20120601
Gustatory perception and fat body energy metabolism are jointly affected by vitellogenin and juvenile hormone in honey bees. PLoS genetics 20120601
Aggressive behavior and reproductive physiology in females of the social cichlid fish Cichlasoma dimerus. Physiology & behavior 20120515
Rapid, simultaneous and nanomolar determination of pyroglutamic acid and cis-/trans-urocanic acid in human stratum corneum by hydrophilic interaction liquid chromatography (HILIC)-electrospray ionization tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120515
Biomimetic synthesis, antibacterial activity and structure-activity properties of the pyroglutamate core of oxazolomycin. Organic & biomolecular chemistry 20120507
Functional characterization of the adipokinetic hormone in the pea aphid, Acyrthosiphon pisum. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20120501
Decreased lactate and potassium levels in natural moisturizing factor from the stratum corneum of mild atopic dermatitis patients are involved with the reduced hydration state. Journal of dermatological science 20120501
Serum metabolomic profiles from patients with acute kidney injury: a pilot study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120415
New peptide pENW (pGlu-Asn-Trp) inhibits platelet activation by attenuating Akt phosphorylation. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120411
Chiral sensing using an achiral europium(III) complex by induced circularly polarized luminescence. Inorganic chemistry 20120402
UPLC-MS metabolic profiling of second trimester amniotic fluid and maternal urine and comparison with NMR spectral profiling for the identification of pregnancy disorder biomarkers. Molecular bioSystems 20120401
Characterization of cerebrospinal fluid aminoterminally truncated and oxidized amyloid-β peptides. Proteomics. Clinical applications 20120401
Formation of rigid, non-flight forewings (elytra) of a beetle requires two major cuticular proteins. PLoS genetics 20120401
Pyroglutamate amyloid β (Aβ) aggravates behavioral deficits in transgenic amyloid mouse model for Alzheimer disease. The Journal of biological chemistry 20120309
Protective effect of a cysteine prodrug and antioxidant, L-2-oxothiazolidine-4-carboxylate, against ethanol-induced gastric lesions in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20120301
Sequencing and biological effects of an adipokinetic/hypertrehalosemic peptide in the stick insect, Baculum extradentatum. Peptides 20120301
Active diuretic peptidomimetic insect kinin analogs that contain β-turn mimetic motif 4-aminopyroglutamate and lack native peptide bonds. Peptides 20120301
The host-seeking inhibitory peptide, Aea-HP-1, is made in the male accessory gland and transferred to the female during copulation. Peptides 20120301
Adipokinetic hormone-induced antioxidant response in Spodoptera littoralis. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120301
Human in vivo longevity is reflected in vitro by differential metabolism as measured by (1)H-NMR profiling of cell culture supernatants. Molecular bioSystems 20120301
ALS patients with mutations in the SOD1 gene have an unique metabolomic profile in the cerebrospinal fluid compared with ALS patients without mutations. Molecular genetics and metabolism 20120301
Zinc l-pyrrolidone carboxylate inhibits the UVA-induced production of matrix metalloproteinase-1 by in vitro cultured skin fibroblasts, whereas it enhances their collagen synthesis. International journal of cosmetic science 20120201
Role of brainstem thyrotropin-releasing hormone-triggered sympathetic overactivation in cardiovascular mortality in type 2 diabetic Goto-Kakizaki rats. Hypertension research : official journal of the Japanese Society of Hypertension 20120201
Elevated cytokinin content in ipt transgenic creeping bentgrass promotes drought tolerance through regulating metabolite accumulation. Journal of experimental botany 20120201
The retina is a target for GnRH-3 system in the European sea bass, Dicentrarchus labrax. General and comparative endocrinology 20120201
Determination of nonprotein amino acids and betaines in vegetable oils by flow injection triple-quadrupole tandem mass spectrometry: a screening method for the detection of adulterations of olive oils. Journal of agricultural and food chemistry 20120201
Quantitative determination of pidotimod in human plasma by liquid chromatography tandem mass spectrometry: application to a bioequivalence study. Arzneimittel-Forschung 20120201
Acute hyperglycemia is related to gastrointestinal symptoms in motion sickness: an experimental study. Physiology & behavior 20120118
Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease. Neurobiology of aging 20120101
Two flushing-like reaction cases from calcium pidolate who tolerated calcium carbonate. Allergologia et immunopathologia 20120101
Detection of peri-synaptic amyloid-β pyroglutamate aggregates in early stages of Alzheimer's disease and in AβPP transgenic mice using a novel monoclonal antibody. Journal of Alzheimer's disease : JAD 20120101
The effect of adipokinetic hormone on midgut characteristics in Pyrrhocoris apterus L. (Heteroptera). Journal of insect physiology 20120101
Hyperphosphorylated tau in young and middle-aged subjects. Acta neuropathologica 20120101
Novel protocol for the chemical synthesis of crustacean hyperglycemic hormone analogues--an efficient experimental tool for studying their functions. PloS one 20120101
Substrate specificity within a family of outer membrane carboxylate channels. PLoS biology 20120101
Proteomic analysis of Trypanosoma cruzi epimastigotes subjected to heat shock. Journal of biomedicine & biotechnology 20120101
Esophageal cancer metabolite biomarkers detected by LC-MS and NMR methods. PloS one 20120101
A distinct metabolic signature predicts development of fasting plasma glucose. Journal of clinical bioinformatics 20120101
Therapeutic use of a cationic antimicrobial peptide from the spider Acanthoscurria gomesiana in the control of experimental candidiasis. BMC microbiology 20120101
Delayed administration of pyroglutamate helix B surface peptide (pHBSP), a novel nonerythropoietic analog of erythropoietin, attenuates acute kidney injury. Molecular medicine (Cambridge, Mass.) 20120101
Astrocytes convert network excitation to tonic inhibition of neurons. BMC biology 20120101
Multicopper oxidase-3 is a laccase associated with the peritrophic matrix of Anopheles gambiae. PloS one 20120101
The potential role of the antioxidant and detoxification properties of glutathione in autism spectrum disorders: a systematic review and meta-analysis. Nutrition & metabolism 20120101
GABA metabolism and transport: effects on synaptic efficacy. Neural plasticity 20120101
Metabolomic applications to decipher gut microbial metabolic influence in health and disease. Frontiers in physiology 20120101
Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders. PloS one 20120101
Selective purification of recombinant neuroactive peptides using the flagellar type III secretion system. mBio 20120101
The structural determinants of insulin-like Peptide 3 activity. Frontiers in endocrinology 20120101
Molecular Structure and Diversity of PBAN/pyrokinin Family Peptides in Ants. Frontiers in endocrinology 20120101
Potassium Channels Blockers from the Venom of Androctonus mauretanicus mauretanicus. Journal of toxicology 20120101
Identification of pigment epithelium-derived factor protein forms with distinct activities on tumor cell lines. Journal of biomedicine & biotechnology 20120101
Chronic acetaminophen ingestion resulting in severe anion gap metabolic acidosis secondary to 5-oxoproline accumulation: an under diagnosed phenomenon. BMJ case reports 20120101
L-2-Oxothiazolidine-4-carboxylic acid or α-lipoic acid attenuates airway remodeling: involvement of nuclear factor-κB (NF-κB), nuclear factor erythroid 2p45-related factor-2 (Nrf2), and hypoxia-inducible factor (HIF). International journal of molecular sciences 20120101
Disturbed Ca2+ homeostasis increases glutaminyl cyclase expression; connecting two early pathogenic events in Alzheimer's disease in vitro. PloS one 20120101
Identification and functional characterization of two orphan G-protein-coupled receptors for adipokinetic hormones from silkworm Bombyx mori. The Journal of biological chemistry 20111209
Neuroprotective effects of neurokinin receptor one in dopaminergic neurons are mediated through Akt/PKB cell signaling pathway. Neuropharmacology 20111201
Preliminary findings on the use of metadoxine for the treatment of alcohol dependence and alcoholic liver disease. Human psychopharmacology 20111201
Engineering of conotoxins for the treatment of pain. Current pharmaceutical design 20111201
[Study on the chemical constituents from the ethyl acetate extracts of Cremastra appendiculata]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20111201
Pyroglutamate-Aβ 3 and 11 colocalize in amyloid plaques in Alzheimer's disease cerebral cortex with pyroglutamate-Aβ 11 forming the central core. Neuroscience letters 20111114
Pyroglutamate amyloid-β (Aβ): a hatchet man in Alzheimer disease. The Journal of biological chemistry 20111111
Radiolabeled CCK/gastrin peptides for imaging and therapy of CCK2 receptor-expressing tumors. Amino acids 20111101
Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin. The Journal of investigative dermatology 20111101
HPLC-MS/MS methods for the quantitative analysis of 5-oxoproline (pyroglutamate) in rat plasma and hepatic cell line culture medium. Journal of pharmaceutical and biomedical analysis 20111101
Cuts by caspase-14 control the proteolysis of filaggrin. The Journal of investigative dermatology 20111101
An invertebrate [hydroxyproline]-modified neuropeptide: further evidence for a close evolutionary relationship between insect adipokinetic hormone and mammalian gonadotropin hormone family. Biochemical and biophysical research communications 20111028
Spirocyclic systems derived from pyroglutamic acid. Organic & biomolecular chemistry 20111021
A facile Cu(I)/BINAP-catalyzed asymmetric approach to functionalized pyroglutamate derivatives bearing a unique quaternary stereogenic center. Organic letters 20111021
Identification of carbonylated peptides by tandem mass spectrometry using a precursor ion-like scan in negative ion mode. Journal of proteomics 20111019
Recurrent anion gap metabolic acidosis in a woman with vertebral disc disease. The American journal of emergency medicine 20111001
Chronic alcohol ingestion exacerbates lung epithelial barrier dysfunction in HIV-1 transgenic rats. Alcoholism, clinical and experimental research 20111001
Anti-diabetic effect of pyroglutamic acid in type 2 diabetic Goto-Kakizaki rats and KK-Ay mice. The British journal of nutrition 20111001
Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase. The Journal of endocrinology 20111001
Sexual dimorphism of gonadotropin-releasing hormone type-III (GnRH3) neurons and hormonal sex reversal of male reproductive behavior in Mozambique tilapia. Zoological science 20111001
Two new compounds from the endophytic fungus Colletotrichum sp. L10 of Cephalotaxus hainanensis. Journal of Asian natural products research 20111001
Proteomic identification of IPSE/alpha-1 as a major hepatotoxin secreted by Schistosoma mansoni eggs. PLoS neglected tropical diseases 20111001
CSAR benchmark exercise of 2010: selection of the protein-ligand complexes. Journal of chemical information and modeling 20110926
Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. Oncogene 20110922
Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aβ is induced by pyroglutamate-Aβ formation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110907
The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions. EMBO molecular medicine 20110901
L-2-oxothiazolidine-4-carboxylate influence on age- and heat exposure-dependent redox changes in rat's blood plasma. The journal of physiological sciences : JPS 20110901
Proteomic analysis of human skin treated with larval schistosome peptidases reveals distinct invasion strategies among species of blood flukes. PLoS neglected tropical diseases 20110901
Reduced levels of IgM autoantibodies against N-truncated pyroglutamate Aβ in plasma of patients with Alzheimer's disease. Neurobiology of aging 20110801
Metabolomic phenotype of gastric cancer and precancerous stages based on gas chromatography time-of-flight mass spectrometry. Journal of gastroenterology and hepatology 20110801
Intraneuronal Aβ as a trigger for neuron loss: can this be translated into human pathology? Biochemical Society transactions 20110801
A capillary electrophoresis-tandem mass spectrometry methodology for the determination of non-protein amino acids in vegetable oils as novel markers for the detection of adulterations in olive oils. Journal of chromatography. A 20110729
Enhanced enzymatic stability and antitumor activity of daunorubicin-GnRH-III bioconjugates modified in position 4. Bioconjugate chemistry 20110720
Selecting protein N-terminal peptides by combined fractional diagonal chromatography. Nature protocols 20110714
In vitro degradation and antitumor activity of oxime bond-linked daunorubicin-GnRH-III bioconjugates and DNA-binding properties of daunorubicin-amino acid metabolites. Amino acids 20110701
Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity. Allergy 20110701
Transport via SLC5A8 (SMCT1) is obligatory for 2-oxothiazolidine-4-carboxylate to enhance glutathione production in retinal pigment epithelial cells. Investigative ophthalmology & visual science 20110701
Expression of vesicular glutamate transporter-2.1 in medaka terminal nerve gonadotrophin-releasing hormone neurones. Journal of neuroendocrinology 20110701
NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation. PLoS genetics 20110701
Angiotensin II type 1 receptor signaling regulates feeding behavior through anorexigenic corticotropin-releasing hormone in hypothalamus. The Journal of biological chemistry 20110617
Glutathione is a physiologic reservoir of neuronal glutamate. Biochemical and biophysical research communications 20110617
Synthesis of quaternary stereogenic centres via stereoselective intermolecular Friedel-Crafts reactions. Organic & biomolecular chemistry 20110607
Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms. Acta neuropathologica 20110601
Microbial community and metabolomic comparison of irritable bowel syndrome faeces. Journal of medical microbiology 20110601
Water-in-oil-in-water double emulsions: an excellent delivery system for improving the oral bioavailability of pidotimod in rats. Journal of pharmaceutical sciences 20110601
Self-double-emulsifying drug delivery system (SDEDDS): a new way for oral delivery of drugs with high solubility and low permeability. International journal of pharmaceutics 20110516
Oxidative stress elicited by insecticides: a role for the adipokinetic hormone. General and comparative endocrinology 20110515
Cigarette smoke-induced changes to alveolar macrophage phenotype and function are improved by treatment with procysteine. American journal of respiratory cell and molecular biology 20110501
In vivo and in vitro assessment of the role of glutathione antioxidant system in anthracycline-induced cardiotoxicity. Archives of toxicology 20110501
Brain-gut interactions between central vagal activation and abdominal surgery to influence gastric myenteric ganglia Fos expression in rats. Peptides 20110501
A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis. Molecular & cellular proteomics : MCP 20110501
Complete genome sequence of Bacteroides salanitronis type strain (BL78). Standards in genomic sciences 20110429
Non-contiguous finished genome sequence of Bacteroides coprosuis type strain (PC139). Standards in genomic sciences 20110429
Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development. The Journal of biological chemistry 20110422
Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding. The Journal of biological chemistry 20110408
N-terminal glutamate to pyroglutamate conversion in vivo for human IgG2 antibodies. The Journal of biological chemistry 20110401
Organization of two independent kisspeptin systems derived from evolutionary-ancient kiss genes in the brain of zebrafish. Endocrinology 20110401
Continuous stress-induced dopamine dysregulation augments PAP-I and PAP-II expression in melanotrophs of the pituitary gland. Biochemical and biophysical research communications 20110401
Temperature affects brain and pituitary gene expression related to reproduction and growth in the male blue gouramis, Trichogaster trichopterus. Journal of experimental zoology. Part A, Ecological genetics and physiology 20110401
Novel methodologies for the synthesis of functionalized pyroglutamates. Chemical communications (Cambridge, England) 20110321
The first decapeptide adipokinetic hormone (AKH) in Heteroptera: a novel AKH from a South African saucer bug, Laccocoris spurcus (Naucoridae, Laccocorinae). Peptides 20110301
Non-invasive monitoring of L-2-oxothiazolidine-4-carboxylate metabolism in the rat brain by in vivo 13C magnetic resonance spectroscopy. Neurochemical research 20110301
Chiral recognition at one-dimensional metal-organic coordination networks initiates the ordering of prochiral catalytic reagent methylacetoacetate on Au{111}. Langmuir : the ACS journal of surfaces and colloids 20110301
Arginine-vasopressin V1a receptor inhibition improves neurologic outcomes following an intracerebral hemorrhagic brain injury. Neurochemistry international 20110301
Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice. The Journal of biological chemistry 20110211
Efficient total synthesis of (-)-stemoamide. Organic & biomolecular chemistry 20110207
Mind the gap! An unusual metabolic acidosis. Lancet (London, England) 20110205
Calcium and zinc complexes of pyrroglutamate analogs detected by electrospray ionization mass spectrometry. Amino acids 20110201
Zebrafish sod1 and sp1 expression are modulated by the copper ATPase gene atp7a in response to intracellular copper status. Chemico-biological interactions 20110201
Removal of N-terminal blocking groups from proteins. Current protocols in protein science 20110201
[Role of the brain in the regulation of metabolism and energy expenditure: the central role of insulin, and insulin resistance of the brain]. Orvosi hetilap 20110116
Seasonal changes of brain GnRH-I, -II, and -III during the final reproductive period in adult male and female sea lamprey. General and comparative endocrinology 20110115
A method for N-terminal de novo sequencing of Nα-blocked proteins by mass spectrometry. The Analyst 20110107
The systemic inhibition of nitric oxide production rapidly regulates TRH mRNA concentration in the paraventricular nucleus of the hypothalamus and serum TSH concentration. Studies in control and cold-stressed rats. Brain research 20110107
Luteinizing Hormone-Releasing Hormone (LHRH)-I antagonist cetrorelix inhibits myeloma cell growth in vitro and in vivo. Molecular cancer therapeutics 20110101
A small nonerythropoietic helix B surface peptide based upon erythropoietin structure is cardioprotective against ischemic myocardial damage. Molecular medicine (Cambridge, Mass.) 20110101
A human ribonuclease induces apoptosis associated with p21WAF1/CIP1 induction and JNK inactivation. BMC cancer 20110101
Ceramide and Related-Sphingolipid Levels Are Not Altered in Disease-Associated Brain Regions of APP and APP/PS1 Mouse Models of Alzheimer's Disease: Relationship with the Lack of Neurodegeneration? International journal of Alzheimer's disease 20110101
Malate plays a crucial role in starch metabolism, ripening, and soluble solid content of tomato fruit and affects postharvest softening. The Plant cell 20110101
Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation. Molecular neurodegeneration 20110101
The proteomic profile of hereditary inclusion body myopathy. PloS one 20110101
Characterisation of human embryonic stem cells conditioning media by 1H-nuclear magnetic resonance spectroscopy. PloS one 20110101
The human serum metabolome. PloS one 20110101
Breaking up the C complex spliceosome shows stable association of proteins with the lariat intron intermediate. PloS one 20110101
The putative AKH receptor of the tobacco hornworm, Manduca sexta, and its expression. Journal of insect science (Online) 20110101
A nonerythropoietic peptide that mimics the 3D structure of erythropoietin reduces organ injury/dysfunction and inflammation in experimental hemorrhagic shock. Molecular medicine (Cambridge, Mass.) 20110101
Chemical modification of L-glutamine to alpha-amino glutarimide on autoclaving facilitates Agrobacterium infection of host and non-host plants: A new use of a known compound. BMC chemical biology 20110101
Calpain-catalyzed proteolysis of human dUTPase specifically removes the nuclear localization signal peptide. PloS one 20110101
cDNA sequence and Fab crystal structure of HL4E10, a hamster IgG lambda light chain antibody stimulatory for γδ T cells. PloS one 20110101
NC1900, an arginine vasopressin analogue, fails to reduce brain edema and improve neurobehavioral deficits in an intracerebral hemorrhagic stroke mice model. Acta neurochirurgica. Supplement 20110101
Isolation and identification of the umami enhancing compounds in Japanese soy sauce. Bioscience, biotechnology, and biochemistry 20110101
A window into the heterogeneity of human cerebrospinal fluid Aβ peptides. Journal of biomedicine & biotechnology 20110101
The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation. Advances in pharmacological sciences 20110101
The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4. PloS one 20110101
Big defensins, a diverse family of antimicrobial peptides that follows different patterns of expression in hemocytes of the oyster Crassostrea gigas. PloS one 20110101
Integrated proteomic and metabolomic analysis of an artificial microbial community for two-step production of vitamin C. PloS one 20110101
Ulcerogenic Helicobacter pylori strains isolated from children: a contribution to get insight into the virulence of the bacteria. PloS one 20110101
Physicochemical and biological characterization of 1E10 anti-idiotype vaccine. BMC biotechnology 20110101
Cord blood glutathione depletion in preterm infants: correlation with maternal cysteine depletion. PloS one 20110101
[Dynamics of antipirin test at patients with alcoholic liver disease on the background of metadoksin drug receiving]. Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20110101
Prediction of protein modification sites of pyrrolidone carboxylic acid using mRMR feature selection and analysis. PloS one 20110101
Susceptibility to dental caries and the salivary proline-rich proteins. International journal of dentistry 20110101
Pyroglutamic aciduria: a cause of high anion-gap metabolic acidosis associated with common drugs. Irish medical journal 20110101
The adipokinetic hormone family in Chrysomeloidea: structural and functional considerations. ZooKeys 20110101
Effect of alcohol structure on the optimum condition for novozym 435-catalyzed synthesis of adipate esters. Biotechnology research international 20110101
Metabolite Signature during Short-Day Induced Growth Cessation in Populus. Frontiers in plant science 20110101
Functional Characterization of Hypertrehalosemic Hormone Receptor in Relation to Hemolymph Trehalose and to Oxidative Stress in the Cockroach Blattella germanica. Frontiers in endocrinology 20110101
Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis. The Journal of biological chemistry 20101231
Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family. Toxicological sciences : an official journal of the Society of Toxicology 20101201
Cytotoxicity of dentine bonding agents on human pulp cells is related to intracellular glutathione levels. International endodontic journal 20101201
Influence of synthetic lamprey GnRH-III on gonadotropin release and steroid hormone levels in gilts. Theriogenology 20101201
Cold ambient temperature reverses abdominal surgery-induced delayed gastric emptying and decreased plasma ghrelin levels in rats. Peptides 20101201
Pyroglutamate-Aβ: role in the natural history of Alzheimer's disease. The international journal of biochemistry & cell biology 20101201
Recombinant self-assembling peptides as biomaterials for tissue engineering. Biomaterials 20101201
Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus. The Journal of allergy and clinical immunology 20101201
Signal transduction, plasma membrane calcium movements, and pigment translocation in freshwater shrimp chromatophores. Journal of experimental zoology. Part A, Ecological genetics and physiology 20101101
Urinary metabonomics study in a rat model in response to protein-energy malnutrition by using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry. Molecular bioSystems 20101101
The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. Plant physiology 20101101
Effects of Manduca sexta allatostatin and an analogue on the peach-potato aphid Myzus persicae (hemiptera: aphididae) and degradation by enzymes in the aphid gut. Archives of insect biochemistry and physiology 20101101
Ectodomain shedding generates Neoepitopes on collagen XVII, the major autoantigen for bullous pemphigoid. Journal of immunology (Baltimore, Md. : 1950) 20101015
A unified strategy targeting the thiodiketopiperazine mycotoxins exserohilone, gliotoxin, the epicoccins, the epicorazines, rostratin A and aranotin. Chemistry (Weinheim an der Bergstrasse, Germany) 20101011
Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein. Journal of medicinal chemistry 20100923
Biodegradable poly(ethylene glycol) hydrogels based on a self-elimination degradation mechanism. Biomaterials 20100901
Zinc ions bind to and inhibit activated protein C. Thrombosis and haemostasis 20100901
Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor. Bioorganic & medicinal chemistry letters 20100901
5-oxoproline-induced anion gap metabolic acidosis after an acute acetaminophen overdose. The Journal of the American Osteopathic Association 20100901
Profound metabolic acidosis from pyroglutamic acidemia: an underappreciated cause of high anion gap metabolic acidosis. CJEM 20100901
Potent hyperglycemic and hyperinsulinemic effects of thyrotropin-releasing hormone microinjected into the rostroventrolateral medulla and abnormal responses in type 2 diabetic rats. Neuroscience 20100825
Crystal structure and functional analysis of the glutaminyl cyclase from Xanthomonas campestris. Journal of molecular biology 20100820
Complementary treatment with oral pidotimod plus vitamin C after laser vaporization for female genital warts: a prospective study. Journal of medicine and life 20100815
Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease. Acta neuropathologica 20100801
Characterization of intrathecally administered hemokinin-1-induced nociceptive behaviors in mice. Peptides 20100801
Hydrophilic interaction liquid chromatography-tandem mass spectrometry for the determination of adefovir in human plasma and its application to a pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100801
Adult Drosophila melanogaster as a model for the study of glucose homeostasis. Aging 20100801
Negligible effect of oral garlic oil on the oral absorption of pyridoxine in metadoxine in rats. Archives of pharmacal research 20100701
Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter. Biochimica et biophysica acta 20100601
OXP1/YKL215c encodes an ATP-dependent 5-oxoprolinase in Saccharomyces cerevisiae: functional characterization, domain structure and identification of actin-like ATP-binding motifs in eukaryotic 5-oxoprolinases. FEMS yeast research 20100601
Acute administration of 5-oxoproline induces oxidative damage to lipids and proteins and impairs antioxidant defenses in cerebral cortex and cerebellum of young rats. Metabolic brain disease 20100601
Signal pathway of GnRH-III inhibiting FSH-induced steroidogenesis in granulosa cells. Frontiers in bioscience (Elite edition) 20100601
Synthetic α-conotoxin mutants as probes for studying nicotinic acetylcholine receptors and in the development of novel drug leads. Toxins 20100601
A role of Histidine151 in the lamprey gonadotropin-releasing hormone receptor-1 (lGnRHR-1): Functional insight of diverse amino acid residues in the position of Tyr of the DRY motif in GnRHR from an ancestral type II receptor. General and comparative endocrinology 20100501
Locust adipokinetic hormones mobilize diacylglycerols selectively. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20100501
Accumulation of intraneuronal Abeta correlates with ApoE4 genotype. Acta neuropathologica 20100501
Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria. The Plant cell 20100501
Cytotoxicity of chlorhexidine on human osteoblastic cells is related to intracellular glutathione levels. International endodontic journal 20100501
Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer. Analytical chemistry 20100415
Metabolomics revealed novel isoflavones and optimal cultivation time of Cordyceps militaris fermentation. Journal of agricultural and food chemistry 20100414
A second gene encodes the anti-diuretic hormone in the insect, Rhodnius prolixus. Molecular and cellular endocrinology 20100412
Neuropeptidomics of the mosquito Aedes aegypti. Journal of proteome research 20100405
Quantification of thyrotropin-releasing hormone by liquid chromatography-electrospray mass spectrometry. Amino acids 20100401
A novel function of red pigment-concentrating hormone in crustaceans: Porcellio scaber (Isopoda) as a model species. General and comparative endocrinology 20100401
Glutathione modulators reverse the pro-tumour effect of growth factors enhancing WiDr cell response to chemotherapeutic agents. Anticancer research 20100401
(2S,4R)-4-Ammonio-5-oxopyrrolidine-2-carboxylate. Acta crystallographica. Section E, Structure reports online 20100401
Identification and characterization of gamma-glutamylamine cyclotransferase, an enzyme responsible for gamma-glutamyl-epsilon-lysine catabolism. The Journal of biological chemistry 20100326
Synthesis of amino acid conjugates to 2-imino-3-methylene-5-carboxypyrrolidine and 2-imino-3-methylene-6-carboxypiperidine. Bioorganic & medicinal chemistry letters 20100315
A pilot study of gas chromatograph/mass spectrometry-based serum metabolic profiling of colorectal cancer after operation. Molecular biology reports 20100301
Biological activity of the predicted red pigment-concentrating hormone of Daphnia pulex in a crustacean and an insect. General and comparative endocrinology 20100301
A novel member of the adipokinetic peptide family in a 'living fossil', the ice crawler Galloisiana yuasai, is the first identified neuropeptide from the order Grylloblattodea. Peptides 20100301
APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis. Brain structure & function 20100301
Metabolic profiling of Arabidopsis thaliana epidermal cells. Journal of experimental botany 20100301
A futile cycle, formed between two ATP-dependant gamma-glutamyl cycle enzymes, gamma-glutamyl cysteine synthetase and 5-oxoprolinase: the cause of cellular ATP depletion in nephrotic cystinosis? Journal of biosciences 20100301
Studies in serum support rapid formation of disulfide bond between unpaired cysteine residues in the VH domain of an immunoglobulin G1 molecule. Analytical biochemistry 20100201
Animal Toxins: How is Complexity Represented in Databases? Toxins 20100201
Metabolomics analysis reveals the compositional differences of shade grown tea (Camellia sinensis L.). Journal of agricultural and food chemistry 20100113
Molecular and mass spectral identification of the broadly conserved decapod crustacean neuropeptide pQIRYHQCYFNPISCF: the first PISCF-allatostatin (Manduca sexta- or C-type allatostatin) from a non-insect. General and comparative endocrinology 20100101
Effect of anorexinergic peptides, cholecystokinin (CCK) and cocaine and amphetamine regulated transcript (CART) peptide, on the activity of neurons in hypothalamic structures of C57Bl/6 mice involved in the food intake regulation. Peptides 20100101
Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases. Journal of neural transmission (Vienna, Austria : 1996) 20100101
Predicting Arabidopsis freezing tolerance and heterosis in freezing tolerance from metabolite composition. Molecular plant 20100101
An integrated functional genomic study of acute phenobarbital exposure in the rat. BMC genomics 20100101
To protect peptide pharmaceuticals against peptidases. Journal of pharmacological and toxicological methods 20100101
Phosphoproteomes of Strongylocentrotus purpuratus shell and tooth matrix: identification of a major acidic sea urchin tooth phosphoprotein, phosphodontin. Proteome science 20100101
Alterations in the red blood cell membrane proteome in alzheimer's subjects reflect disease-related changes and provide insight into altered cell morphology. Proteome science 20100101
The zebra finch neuropeptidome: prediction, detection and expression. BMC biology 20100101
[Comparative study of magnesium salts bioavailability in rats fed a magnesium-deficient diet]. Vestnik Rossiiskoi akademii meditsinskikh nauk 20100101
Trypsin-induced proteome alteration during cell subculture in mammalian cells. Journal of biomedical science 20100101
Generating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamides. Marine drugs 20100101
FluTyper-an algorithm for automated typing and subtyping of the influenza virus from high resolution mass spectral data. BMC bioinformatics 20100101
Comparative quantitative mass spectrometry analysis of MHC class II-associated peptides reveals a role of GILT in formation of self-peptide repertoire. PloS one 20100101
Intracellular accumulation of amyloid-Beta - a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease. Frontiers in aging neuroscience 20100101
Proteomic analysis of sea urchin (Strongylocentrotus purpuratus) spicule matrix. Proteome science 20100101
The collagen V homotrimer [alpha1(V)](3) production is unexpectedly favored over the heterotrimer [alpha1(V)](2)alpha2(V) in recombinant expression systems. Journal of biomedicine & biotechnology 20100101
Benzothiadiazole and l-2-oxothiazolidine-4-carboxylic acid reduce the severity of Sharka symptoms in pea leaves: effect on antioxidative metabolism at the subcellular level. Plant biology (Stuttgart, Germany) 20100101
Parenteral nutrition: Revisited. Indian journal of anaesthesia 20100101
A global metabolic shift is linked to Salmonella multicellular development. PloS one 20100101
[Severe metabolic acidosis as a result of 5-oxoproline in acetaminophen use]. Nederlands tijdschrift voor geneeskunde 20100101
Pathological Hallmarks, Clinical Parallels, and Value for Drug Testing in Alzheimer's Disease of the APP[V717I] London Transgenic Mouse Model. International journal of Alzheimer's disease 20100101
Neuron loss in transgenic mouse models of Alzheimer's disease. International journal of Alzheimer's disease 20100101
Procysteine increases alcohol-depleted glutathione stores in rat plantaris following a period of abstinence. Alcohol and alcoholism (Oxford, Oxfordshire) 20100101
Chronic myeloid leukemia patients sensitive and resistant to imatinib treatment show different metabolic responses. PloS one 20100101
Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling. PloS one 20100101
Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease. International journal of Alzheimer's disease 20100101
Alzheimer's Aβ peptides with disease-associated N-terminal modifications: influence of isomerisation, truncation and mutation on Cu2+ coordination. PloS one 20100101
PEDF - A Noninhibitory Serpin with Neurotrophic Activity. Acta naturae 20100101
Glutaminyl cyclases display significant catalytic proficiency for glutamyl substrates. Biochemistry 20091222
Characterization of Chinese liquor starter, 'Daqu', by flavor type with 1H NMR-based nontargeted analysis. Journal of agricultural and food chemistry 20091209
Developmental expression and subcellular localization of glutaminyl cyclase in mouse brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20091201
Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies. Psychopharmacology 20091201
Bioorganic synthesis of a recombinant HIV-1 fusion inhibitor, SC35EK, with an N-terminal pyroglutamate capping group. Bioorganic & medicinal chemistry 20091201
Inhibitors for human glutaminyl cyclase by structure based design and bioisosteric replacement. Journal of medicinal chemistry 20091126
From N-triisopropylsilylpyrrole to an optically active C-4 substituted pyroglutamic acid: total synthesis of penmacric acid. Organic & biomolecular chemistry 20091107
Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level. International immunopharmacology 20091101
Incorporation of N-amidino-pyroglutamic acid into peptides using intramolecular cyclization of alpha-guanidinoglutaric acid. Journal of peptide science : an official publication of the European Peptide Society 20091101
Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics. The FEBS journal 20091101
Natural moisturizing factor components in the stratum corneum as biomarkers of filaggrin genotype: evaluation of minimally invasive methods. The British journal of dermatology 20091101
4,4'-Bipyridine-pyroglutamic acid (1/2). Acta crystallographica. Section E, Structure reports online 20091101
Spinal ERK activation via NO-cGMP pathway contributes to nociceptive behavior induced by morphine-3-glucuronide. Biochemical pharmacology 20091015
Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model. Acta neuropathologica 20091001
Characterization of a novel alpha4/4-conotoxin, Qc1.2, from vermivorous Conus quercinus. Acta biochimica et biophysica Sinica 20091001
Glutathione modulation reverses the growth-promoting effect of growth factors, improving the 5-fluorouracil antitumour response in WiDr colon cancer cells. Anticancer research 20091001
The protective effects of N-Acetl-cysteine, oxo-thiazolidine-carboxylate, acetaminophen and their combinations against sulfur mustard cytotoxicity on human skin fibroblast cell line (HF2FF). Iranian biomedical journal 20091001
Pulmonary exposure to diesel exhaust particles promotes cerebral microvessel thrombosis: protective effect of a cysteine prodrug l-2-oxothiazolidine-4-carboxylic acid. Toxicology 20090919
Immunodominant epitope and properties of pyroglutamate-modified Abeta-specific antibodies produced in rabbits. Journal of neuroimmunology 20090818
High-performance liquid chromatography-tandem mass spectrometry for the determination of pidotimod in human plasma and its application to a pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090815
Metadoxine, an ion-pair of pyridoxine and L-2-pyrrolidone-5-carboxylate, blocks adipocyte differentiation in association with inhibition of the PKA-CREB pathway. Archives of biochemistry and biophysics 20090815
A novel anti-platelet aggregation tripeptide from Agkistrodon acutus venom: isolation and characterization. Toxicon : official journal of the International Society on Toxinology 20090801
Procysteine stimulates expression of key anabolic factors and reduces plantaris atrophy in alcohol-fed rats. Alcoholism, clinical and experimental research 20090801
Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis. International journal of molecular medicine 20090801
Concise asymmetric synthesis of configurationally stable 4-trifluoromethyl thalidomide. Future medicinal chemistry 20090801
Pyroglutamate formation influences solubility and amyloidogenicity of amyloid peptides. Biochemistry 20090728
L-2-Oxothiazolidine-4-carboxylate reverses glutathione oxidation and delays fatigue of skeletal muscle in vitro. Journal of applied physiology (Bethesda, Md. : 1985) 20090701
Pyroglutamic acid promotes survival of retinal ganglion cells after optic nerve injury. Current eye research 20090701
Structures of Abeta-related peptide--monoclonal antibody complexes. Biochemistry 20090616
Efficient, high-speed methane fermentation for sewage sludge using subcritical water hydrolysis as pretreatment. Bioresource technology 20090601
Tanycyte pyroglutamyl peptidase II contributes to regulation of the hypothalamic-pituitary-thyroid axis through glial-axonal associations in the median eminence. Endocrinology 20090501
Desflurane but not sevoflurane can increase lung resistance via tachykinin pathways. British journal of anaesthesia 20090501
MicroRNA: Implications for Alzheimer Disease and other Human CNS Disorders. Current genomics 20090501
Identification of SYWKQCAFNAVSCFamide: a broadly conserved crustacean C-type allatostatin-like peptide with both neuromodulatory and cardioactive properties. The Journal of experimental biology 20090415
The orientation of BN-related peptides adsorbed on SERS-active silver nanoparticles: comparison with a silver electrode surface. The journal of physical chemistry. B 20090409
Peptides of the adipokinetic hormone/red pigment-concentrating hormone family: a new take on biodiversity. Annals of the New York Academy of Sciences 20090401
Gastric electrical stimulation for obesity: the need for a new device using wider pulses. Obesity (Silver Spring, Md.) 20090301
Emended description of Actinomyces naeslundii and descriptions of Actinomyces oris sp. nov. and Actinomyces johnsonii sp. nov., previously identified as Actinomyces naeslundii genospecies 1, 2 and WVA 963. International journal of systematic and evolutionary microbiology 20090301
Production of shelf-stable ranch dressing using high-pressure processing. Journal of food science 20090301
[Capsule metadoxine in the treatment of alcoholic liver disease: a randomized, double-blind, placebo-controlled, multicenter study]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090301
Metabolomic investigation into variation of endogenous metabolites in professional athletes subject to strength-endurance training. Journal of applied physiology (Bethesda, Md. : 1985) 20090201
Conversion of 4-oxoproline esters to 4-substituted pyrrole-2-carboxylic acid esters. Chemical & pharmaceutical bulletin 20090201
NMDA receptor up-regulates pyroglutamyl peptidase II activity in the rat hippocampus. Neuroscience letters 20090116
Chemical constituents of imported Rosae fructus. Journal of natural medicines 20090101
Anticoagulant and antithrombotic activity of a new peptide pENW (pGlu-Asn-Trp). The Journal of pharmacy and pharmacology 20090101
Arginine, scurvy and Cartier's 'tree of life'. Journal of ethnobiology and ethnomedicine 20090101
A proteomic approach for studying insect phylogeny: CAPA peptides of ancient insect taxa (Dictyoptera, Blattoptera) as a test case. BMC evolutionary biology 20090101
New therapeutic approach to Tourette Syndrome in children based on a randomized placebo-controlled double-blind phase IV study of the effectiveness and safety of magnesium and vitamin B6. Trials 20090101
Insight into the regulation of glycan synthesis in Drosophila chaoptin based on mass spectrometry. PloS one 20090101
Incomplete posttranslational prohormone modifications in hyperactive neuroendocrine cells. BMC cell biology 20090101
Pidotimod: a reappraisal. International journal of immunopathology and pharmacology 20090101
NK1 receptor-mediated endothelium-dependent relaxation and contraction with different sensitivity to post-receptor signaling in pulmonary arteries. Vascular pharmacology 20090101
Neuroendocrine transcriptional programs adapt dynamically to the supply and demand for neuropeptides as revealed in NSF mutant zebrafish. Neural development 20090101
A review of COFRADIC techniques targeting protein N-terminal acetylation. BMC proceedings 20090101
ETISEQ--an algorithm for automated elution time ion sequencing of concurrently fragmented peptides for mass spectrometry-based proteomics. BMC bioinformatics 20090101
What have worm models told us about the mechanisms of neuronal dysfunction in human neurodegenerative diseases? Molecular neurodegeneration 20090101
Amino acids - Guidelines on Parenteral Nutrition, Chapter 4. German medical science : GMS e-journal 20090101
[Non-alcoholic fatty liver disease: age peculiarities, breakthrough in pathogenetic therapy]. Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101
Synthesis of highly substituted pyroglutamates via a domino Michael addition-Claisen rearrangement-lactamisation approach. Organic & biomolecular chemistry 20081221
Acute alcohol intoxication. European journal of internal medicine 20081201
Biological activity and identification of neuropeptides in the neurosecretory complexes of the cabbage pest insect, Mamestra brassicae (Noctuidae; Lepidoptera). Acta biologica Hungarica 20081201
Synergistic immunostimulatory effect of pidotimod and red ginseng acidic polysaccharide on humoral immunity of immunosuppressed mice. Die Pharmazie 20081201
Synthesis of the phosphinic analogue of thyrotropin releasing hormone. The Journal of organic chemistry 20081107
Structural properties of bombesin-like peptides revealed by surface-enhanced Raman scattering on roughened silver electrodes. Biopolymers 20081101
Anterior pituitary pyroglutamyl peptidase II activity controls TRH-induced prolactin release. Peptides 20081101
Stimulatory effects of bioamines norepinephrine and dopamine on locomotion of Pyrrhocoris apterus (L.): is the adipokinetic hormone involved? Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20081101
A gamma-glutamyl transpeptidase-independent pathway of glutathione catabolism to glutamate via 5-oxoproline in Arabidopsis. Plant physiology 20081101
Expression of lipid storage droplet protein-1 may define the role of AKH as a lipid mobilizing hormone in Manduca sexta. Insect biochemistry and molecular biology 20081101
Participation of the cholinergic system in ameliorating effect of vasopressin fragment by group I metabotropic glutamate-receptor blockade. Journal of pharmacological sciences 20081101
Natural variation in plasticity of glucose homeostasis and food intake. The Journal of experimental biology 20081001
Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology. Nature medicine 20081001
Normal saline induces oxidative stress in peritoneal mesothelial cells. Journal of pediatric surgery 20081001
Arabidopsis sterol carrier protein-2 is required for normal development of seeds and seedlings. Journal of experimental botany 20080901
Synergistic immunostimulating activity of pidotimod and red ginseng acidic polysaccharide against cyclophosphamide-induced immunosuppression. Archives of pharmacal research 20080901
Guilty as charged: unmeasured urinary anions in a case of pyroglutamic acidosis. The Netherlands journal of medicine 20080901
5-Oxoproline as a cause of high anion gap metabolic acidosis: an uncommon cause with common risk factors. The Netherlands journal of medicine 20080901
Clinical applications of urinary organic acids. Part I: Detoxification markers. Alternative medicine review : a journal of clinical therapeutic 20080901
Impact of cyclosporine A on magnesium homeostasis: clinical observation in lung transplant recipients and experimental study in mice. Transplantation 20080815
The identification and structural characterization of C7orf24 as gamma-glutamyl cyclotransferase. An essential enzyme in the gamma-glutamyl cycle. The Journal of biological chemistry 20080808
Origins of gonadotropin-releasing hormone (GnRH) in vertebrates: identification of a novel GnRH in a basal vertebrate, the sea lamprey. Endocrinology 20080801
Crotalphine, a novel potent analgesic peptide from the venom of the South American rattlesnake Crotalus durissus terrificus. Peptides 20080801
Inhibition of glutaminyl cyclase prevents pGlu-Abeta formation after intracortical/hippocampal microinjection in vivo/in situ. Journal of neurochemistry 20080801
Alternative pathways for production of beta-amyloid peptides of Alzheimer's disease. Biological chemistry 20080801
Prothyrotropin-releasing hormone targets its processing products to different vesicles of the secretory pathway. The Journal of biological chemistry 20080718
Amyloidogenic processing of amyloid precursor protein: evidence of a pivotal role of glutaminyl cyclase in generation of pyroglutamate-modified amyloid-beta. Biochemistry 20080715
Heterogeneity of monoclonal antibodies. Journal of pharmaceutical sciences 20080701
Increased metal tolerance in Salix by nicotinamide and nicotinic acid. Plant physiology and biochemistry : PPB 20080701
Proteomic analysis of skin invasion by blood fluke larvae. PLoS neglected tropical diseases 20080701
Analysis of glutamine, glutamate, pyroglutamate, and GABA in cerebrospinal fluid using ion pairing HPLC with positive electrospray LC/MS/MS. Journal of neuroscience methods 20080630
Ribonuclease A homologues of the zebrafish: polymorphism, crystal structures of two representatives and their evolutionary implications. Journal of molecular biology 20080627
2-nitrophenyl isocyanide as a versatile convertible isocyanide: rapid access to a fused gamma-lactam beta-lactone bicycle. The Journal of organic chemistry 20080606
Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26. Journal of controlled release : official journal of the Controlled Release Society 20080604
Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease. Brain : a journal of neurology 20080601
Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration. American journal of physiology. Heart and circulatory physiology 20080601
High throughput screening of bradykinin-potentiating peptides in Bothrops moojeni snake venom using precursor ion mass spectrometry. Toxicon : official journal of the International Society on Toxinology 20080601
Toxins from cone snails: properties, applications and biotechnological production. Applied microbiology and biotechnology 20080501
High-performance liquid chromatography-tandem mass spectrometry in the identification and determination of phase I and phase II drug metabolites. Analytical and bioanalytical chemistry 20080501
Determination of primary structure and microheterogeneity of a beta-amyloid plaque-specific antibody using high-performance LC-tandem mass spectrometry. Analytical and bioanalytical chemistry 20080501
Neurokinin-3 peptide instead of neurokinin-1 synergistically exacerbates kainic acid-inducing degeneration of neurons in the substantia nigra of mice. Journal of neurochemistry 20080401
A positive charge at the N-terminal segment of Discrepin increases the blocking effect of K+ channels responsible for the IA currents in cerebellum granular cells. Biochimica et biophysica acta 20080401
Dual negative precursor ion scan approach for rapid detection of glutathione conjugates using liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20080401
Identification of putative crustacean neuropeptides using in silico analyses of publicly accessible expressed sequence tags. General and comparative endocrinology 20080401
Metabolic acidosis in the critically ill: part 2. Causes and treatment. Anaesthesia 20080401
Structure of acostatin, a dimeric disintegrin from Southern copperhead (Agkistrodon contortrix contortrix), at 1.7 A resolution. Acta crystallographica. Section D, Biological crystallography 20080401
Opposing effects of dietary protein and sugar regulate a transcriptional target of Drosophila insulin-like peptide signaling. Cell metabolism 20080401
Rapid action of estrogens on intracellular calcium oscillations in primate luteinizing hormone-releasing hormone-1 neurons. Endocrinology 20080301
Developmental regulation and functions of the expression of the neuropeptide corazonin in Drosophila melanogaster. Cell and tissue research 20080301
Contribution of various metabolites to the 'unmeasured' anions in critically ill patients with metabolic acidosis. Critical care medicine 20080301
Glutaminyl cyclase activity is a characteristic feature of human cerebrospinal fluid. Clinica chimica acta; international journal of clinical chemistry 20080301
A double-blind placebo-controlled study to evaluate the safety and efficacy of L-2-oxothiazolidine-4-carboxylic acid in the treatment of patients with acute respiratory distress syndrome. Critical care medicine 20080301
The Medicinal Mushroom Agaricus blazei Murrill: Review of Literature and Pharmaco-Toxicological Problems. Evidence-based complementary and alternative medicine : eCAM 20080301
Molecular cloning of four cDNAs encoding prepro-crustacean hyperglycemic hormone (CHH) from the eyestalk of the red rock crab Cancer productus: identification of two genetically encoded CHH isoforms and two putative post-translationally derived CHH variants. General and comparative endocrinology 20080201
Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in female animals submitted to food-restriction or dehydration-induced anorexia and cold exposure. Hormones and behavior 20080201
Comparison of insect kinin analogs with cis-peptide bond, type VI-turn motifs identifies optimal stereochemistry for interaction with a recombinant arthropod kinin receptor from the southern cattle tick Boophilus microplus. Peptides 20080201
Characterization of the post-translational modification of recombinant human BMP-15 mature protein. Protein science : a publication of the Protein Society 20080201
Localization and thiol dependancy of endogenous nitro compounds-mediating urethral photo-relaxation. Pflugers Archiv : European journal of physiology 20080101
Phase I study of magnesium pidolate in combination with hydroxycarbamide for children with sickle cell anaemia. British journal of haematology 20080101
Investigation of a wide spectrum of inherited metabolic disorders by 13C NMR spectroscopy. Acta biochimica Polonica 20080101
Identification of Proteins Related to Nickel Homeostasis in Helicobater pylori by Immobilized Metal Affinity Chromatography and Two-Dimensional Gel Electrophoresis. Metal-based drugs 20080101
Unmeasured anions: the unknown unknowns. Critical care (London, England) 20080101
Differentiation of Sclerotinia minor depends on thiol redox state and oxidative stress. Canadian journal of microbiology 20080101
The nature of unmeasured anions in critically ill patients. Critical care (London, England) 20080101
[Effects of an antiischemic drug combination and nimodipine on cerebral blood supply in a hemorrhagic stroke model in rats]. Eksperimental'naia i klinicheskaia farmakologiia 20080101
Contractile effect of tachykinins on Suncus murinus (house musk shrew) isolated ileum. Neuropeptides 20080101
Glutamine affects glutathione recycling enzymes in a DMBA-induced breast cancer model. Nutrition and cancer 20080101
[Chemical constituents of Changium smyrnioides]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080101
Henoch-Schönlein purpura associated with pidotimod therapy. Clinical and experimental rheumatology 20080101
Oxidant-induced atrogin-1 and transforming growth factor-beta1 precede alcohol-related myopathy in rats. Muscle & nerve 20071201
Identification of small molecules from human embryonic stem cells using metabolomics. Stem cells and development 20071201
[Pyroglutamic acidemia associated with acetaminophen]. Anales de pediatria (Barcelona, Spain : 2003) 20071201
Diastereoselective synthesis of glutamate-appended oxolane rings: synthesis of (s)-(+)-lycoperdic acid. The Journal of organic chemistry 20071123
Cytotoxicity of formaldehyde on human osteoblastic cells is related to intracellular glutathione levels. Journal of biomedical materials research. Part B, Applied biomaterials 20071101
Mass spectrometric identification of pyroglutamic acid in peptides following selective hydrolysis. Analytical biochemistry 20071101
Cold exposure increases the biosynthesis and proteolytic processing of prothyrotropin-releasing hormone in the hypothalamic paraventricular nucleus via beta-adrenoreceptors. Endocrinology 20071001
The ameliorative effect of cysteine prodrug L-2-oxothiazolidine-4-carboxylic acid on cisplatin-induced nephrotoxicity in rats. Fundamental & clinical pharmacology 20071001
Isolation and characterization of glutaminyl cyclases from Drosophila: evidence for enzyme forms with different subcellular localization. Biochemistry 20070925
Analysis of post-translational modifications in recombinant monoclonal antibody IgG1 by reversed-phase liquid chromatography/mass spectrometry. Journal of chromatography. A 20070914
Adipokinetic hormone-induced enhancement of antioxidant capacity of Pyrrhocoris apterus hemolymph in response to oxidative stress. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070901
Inhibition of Lewis lung carcinoma growth by Toxoplasma gondii through induction of Th1 immune responses and inhibition of angiogenesis. Journal of Korean medical science 20070901
Profound metabolic acidosis and oxoprolinuria in an adult. Journal of medical toxicology : official journal of the American College of Medical Toxicology 20070901
Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity. Chemico-biological interactions 20070830
Sequencing of T-superfamily conotoxins from Conus virgo: pyroglutamic acid identification and disulfide arrangement by MALDI mass spectrometry. Journal of the American Society for Mass Spectrometry 20070801
Alveolar type II cells from ethanol-fed rats produce a fibronectin-enriched extracellular matrix that promotes monocyte activation. Alcohol (Fayetteville, N.Y.) 20070801
High anion gap metabolic acidosis secondary to pyroglutamic aciduria (5-oxoprolinuria): association with prescription drugs and malnutrition. Annals of clinical biochemistry 20070701
Water scorpions (Heteroptera, Nepidae) and giant water bugs (Heteroptera, Belostomatidae): sources of new members of the adipokinetic hormone/red pigment-concentrating hormone family. Peptides 20070701
Synthesis of a pyridoxine-peptide based delivery system for nucleotides. Chemistry & biodiversity 20070701
Crystal structures of two Bordetella pertussis periplasmic receptors contribute to defining a novel pyroglutamic acid binding DctP subfamily. Journal of molecular biology 20070629
Therapy and clinical trials. Current opinion in lipidology 20070601
Structure-based drug design of pyrrolidine-1, 2-dicarboxamides as a novel series of orally bioavailable factor Xa inhibitors. Chemical biology & drug design 20070601
Magnesium as a preventive treatment for paediatric episodic tension-type headache: results at 1-year follow-up. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20070601
Inhibitory effect of cyclooxygenase inhibitors on the step-through passive avoidance performance in mice treated with NC-1900, an arginine-vasopressin fragment analog. Methods and findings in experimental and clinical pharmacology 20070601
Synthesis of pyroglutamic acid derivatives via double michael reactions of alkynones. Organic letters 20070524
Expeditious access to unprotected racemic pyroglutamic acids. The Journal of organic chemistry 20070511
Oxidative folding and N-terminal cyclization of onconase. Biochemistry 20070508
Is the titer of adipokinetic peptides in Leptinotarsa decemlineata fed on genetically modified potatoes increased by oxidative stress? Peptides 20070501
Quantification of urinary zwitterionic organic acids using weak-anion exchange chromatography with tandem MS detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401
Effects of a bacterial lipid byproduct on human pulp fibroblasts in vitro. Journal of endodontics 20070401
Adipokines in children with sleep disordered breathing. Sleep 20070401
Effect of NC-1900, an active fragment analog of arginine vasopressin, and inhibitors of arachidonic acid metabolism on performance of a passive avoidance task in mice. European journal of pharmacology 20070329
Evidence for interplay between thyrotropin-releasing hormone (TRH) and its structural analogue pGlu-Glu-Pro-NH2 ([Glu2]TRH) in the brain: an in vivo microdialysis study. Neuroscience letters 20070319
Structure design of multifunctional furoate and pyroglutamate esters of dextran by polymer-analogous reactions. Macromolecular bioscience 20070308
alpha-Amino acid derivatives as proton pump inhibitors and potent anti-ulcer agents. European journal of medicinal chemistry 20070301
A novel adipokinetic peptide in a water boatman (Heteroptera, Corixidae) and its bioanalogue in a saucer bug (Heteroptera, Naucoridae). Peptides 20070301
5-Oxoproline reduces non-enzymatic antioxidant defenses in vitro in rat brain. Metabolic brain disease 20070301
Effect of immunisation against gonadotrophin releasing hormone isoforms (mammalian GnRH-I, chicken GnRH-II and lamprey GnRH-III) on murine spermatogenesis. Vaccine 20070301
Oxidative stress contributes to accelerated development of the senescent phenotype in human peritoneal mesothelial cells exposed to high glucose. Free radical biology & medicine 20070301
Calcium movements during pigment aggregation in freshwater shrimp chromatophores. Pigment cell research 20070201
Experimental determination of translational starts using peptide mass mapping and tandem mass spectrometry within the proteome of Mycobacterium tuberculosis. Microbiology (Reading, England) 20070201
Isolation and characterization of the glutaminyl cyclases from Solanum tuberosum and Arabidopsis thaliana: implications for physiological functions. Biological chemistry 20070201
Pharmacokinetics of metadoxine for injection after repeated doses in healthy volunteers. Chinese medical journal 20070120
An analog of thyrotropin-releasing hormone (TRH) is neuroprotective against glutamate-induced toxicity in fetal rat hippocampal neurons in vitro. Brain research 20070112
Cellular colocalization and coregulation between hypothalamic pro-TRH and prohormone convertases in hypothyroidism. American journal of physiology. Endocrinology and metabolism 20070101
Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1. Bioorganic & medicinal chemistry 20070101
Comparison of insect kinin analogs with cis-peptide bond motif 4-aminopyroglutamate identifies optimal stereochemistry for diuretic activity. Biopolymers 20070101
Artificial elevation of glutathione affects symptom development in ZYMV-infected Cucurbita pepo L. plants. Archives of virology 20070101
Structure-activity relationships for in vitro diuretic activity of CAP2b in the housefly. Peptides 20070101
Urticaria due to calcium pidolate. Allergologia et immunopathologia 20070101
Combinatorial solution-phase synthesis of (2S,4S)-4-acylamino-5-oxopyrrolidine-2-carboxamides. Journal of combinatorial chemistry 20070101
Inborn errors in the metabolism of glutathione. Orphanet journal of rare diseases 20070101
Identification of the endogenous key substrates of the human organic cation transporter OCT2 and their implication in function of dopaminergic neurons. PloS one 20070101
Low pH gel intranasal sprays inactivate influenza viruses in vitro and protect ferrets against influenza infection. Respiratory research 20070101
Precise protein quantification based on peptide quantification using iTRAQ. BMC bioinformatics 20070101
Hair and amino acids: the interactions and the effects. Journal of cosmetic science 20070101
Reactions of glycidyl derivatives with ambident nucleophiles; part 2: amino acid derivatives. Beilstein journal of organic chemistry 20070101
Metabolic acidosis. Acta medica Indonesiana 20070101
Peptide ligand screening of alpha-synuclein aggregation modulators by in silico panning. BMC bioinformatics 20070101
Abstracts of papers presented at the 2007 pittsburgh conference. Journal of automated methods & management in chemistry 20070101
Circadian rhythms of TRH-like peptide levels in rat brain. Brain research 20061213
Brainstem thyrotropin-releasing hormone regulates food intake through vagal-dependent cholinergic stimulation of ghrelin secretion. Endocrinology 20061201
High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain. Neuroscience 20061201
Efficient asymmetric synthesis of novel 4-substituted and configurationally stable analogues of thalidomide. Organic letters 20061123
trans-2,5-Disubstituted pyrrolidines: Rapid stereocontrolled access from sulfones. Organic & biomolecular chemistry 20061107
Is lGnRH-III the most potent GnRH analog containing only natural amino acids that specifically inhibits the growth of human breast cancer cells? Journal of peptide science : an official publication of the European Peptide Society 20061101
Unfolding of the immunoglobulin light and heavy chains is required for the enzymatic removal of N-terminal pyroglutamyl residues. Biochimica et biophysica acta 20061101
Psychoneuroendocrinology of anorexia nervosa. Psychoneuroendocrinology 20061101
On the seeding and oligomerization of pGlu-amyloid peptides (in vitro). Biochemistry 20061017
Investigation of N-terminal glutamate cyclization of recombinant monoclonal antibody in formulation development. Journal of pharmaceutical and biomedical analysis 20061011
Improvement of cationic albumin conjugated pegylated nanoparticles holding NC-1900, a vasopressin fragment analog, in memory deficits induced by scopolamine in mice. Behavioural brain research 20061002
Inhibition of glutaminyl cyclase alters pyroglutamate formation in mammalian cells. Biochimica et biophysica acta 20061001
Effects of the tomato pathogen Fusarium oxysporum f. sp. radicis-lycopersici and of the biocontrol bacterium Pseudomonas fluorescens WCS365 on the composition of organic acids and sugars in tomato root exudate. Molecular plant-microbe interactions : MPMI 20061001
Endocrine control of TAG lipase in the fat body of the migratory locust, Locusta migratoria. Insect biochemistry and molecular biology 20061001
Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity. The Journal of biological chemistry 20060929
Occurrence of the free and Peptide forms of pyroglutamic acid in plasma from the portal blood of rats that had ingested a wheat gluten hydrolysate containing pyroglutamyl peptides. Journal of agricultural and food chemistry 20060920
Prostanoids contribute to cutaneous active vasodilation in humans. American journal of physiology. Regulatory, integrative and comparative physiology 20060901
Identification of a new truncated form and deamidation products of fibrinopeptide B released by thrombin from human fibrinogen. Thrombosis and haemostasis 20060901
An unusual cause of severe metabolic acidosis. The Medical journal of Australia 20060821
Pyroglutamate stimulates Na+ -dependent glutamate transport across the blood-brain barrier. FEBS letters 20060807
Cytomodulation of interleukin-2 effect by L-2-oxothiazolidine-4-carboxylate on human malignant melanoma. Cancer immunology, immunotherapy : CII 20060801
Protective role of L-2-oxothiazolidine-4-carboxylic acid in cisplatin-induced renal injury. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801
Persistent 5-oxoprolinuria with normal glutathione synthase and 5-oxoprolinase activities. Journal of inherited metabolic disease 20060801
Homology modeling and site-directed mutagenesis of pyroglutamyl peptidase II. Insights into omega-versus aminopeptidase specificity in the M1 family. The Journal of biological chemistry 20060707
2,5-Disubstituted pyrrolidines: synthesis by enamine reduction and subsequent regioselective and diastereoselective alkylations. Organic & biomolecular chemistry 20060707
Identification of dopamine, gonadotrophin-releasing hormone-I, and vasoactive intestinal peptide neurones activated by electrical stimulation to the medial preoptic area of the turkey hypothalamus: a potential reproductive neuroendocrine circuit. Journal of neuroendocrinology 20060701
The role of tachykinins in circular muscle contractility of the murine ileum: a functional investigation. Autonomic neuroscience : basic & clinical 20060630
An antioxidant modulates expression of receptor activator of NF-kappaB in asthma. Experimental & molecular medicine 20060630
Capillary electrophoresis for caffeine and pyroglutamate determination in coffees study of the in vivo effect on learning and locomotor activity in mice. Journal of pharmaceutical and biomedical analysis 20060616
Characterization of the stability of a fully human monoclonal IgG after prolonged incubation at elevated temperature. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060606
Improving mass accuracy of high performance liquid chromatography/electrospray ionization time-of-flight mass spectrometry of intact antibodies. Journal of the American Society for Mass Spectrometry 20060601
Integrated metabonomic analysis of bromobenzene-induced hepatotoxicity: novel induction of 5-oxoprolinosis. Journal of proteome research 20060601
Hydrolytic cleavage of pyroglutamyl-peptide bond. V. selective removal of pyroglutamic acid from biologically active pyroglutamylpeptides in high concentrations of aqueous methanesulfonic acid. Chemical & pharmaceutical bulletin 20060601
Synthesis of N3,N'3-polymethylene-bis-hydantoins and their macrocyclic derivatives. The Journal of organic chemistry 20060512
Estrogen receptors alpha and beta differentially regulate the transcriptional activity of the Urocortin gene. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060503
Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin. Endocrinology 20060501
Discordant gene expression in skeletal muscle and adipose tissue of patients with type 2 diabetes: effect of interleukin-6 infusion. Diabetologia 20060501
Blood glucose lowering by means of lifestyle intervention has different effects on adipokines as compared with insulin treatment in subjects with type 2 diabetes. Diabetologia 20060501
Fourier transform mass spectrometry: a powerful tool for toxin analysis. Toxicon : official journal of the International Society on Toxinology 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Biochemical characterization of the major sorghum grain peroxidase. The FEBS journal 20060501
Enteral feeding of glycyl-glutamine dipeptide improves the structure and absorptive function of the small intestine after allogenetic liver transplantation in rats. Hepatobiliary & pancreatic diseases international : HBPD INT 20060501
Increased anion gap metabolic acidosis as a result of 5-oxoproline (pyroglutamic acid): a role for acetaminophen. Clinical journal of the American Society of Nephrology : CJASN 20060501
Investigation of a route to ibotenic acid analogues via a reduced pyroglutamate template. Organic & biomolecular chemistry 20060421
Differential receptor activation by cockroach adipokinetic hormones produces differential effects on ion currents, neuronal activity, and locomotion. Journal of neurophysiology 20060401
Pathophysiologically based drug treatment of sickle cell disease. Trends in pharmacological sciences 20060401
Regulation of nicotine-induced cyclooxygenase-2 protein expression in human gingival fibroblasts. Acta pharmacologica Sinica 20060401
Formation of pyroglutamic acid from N-terminal glutamic acid in immunoglobulin gamma antibodies. Analytical chemistry 20060401
Crystal structure of papaya glutaminyl cyclase, an archetype for plant and bacterial glutaminyl cyclases. Journal of molecular biology 20060324
Red pigment concentrating hormone strongly enhances the strength of the feedback to the pyloric rhythm oscillator but has little effect on pyloric rhythm period. Journal of neurophysiology 20060301
The detection of red pigment-concentrating hormone (RPCH) in crustacean eyestalk tissues using matrix-assisted laser desorption/ionization-Fourier transform mass spectrometry: [M + Na]+ ion formation in dried droplet tissue preparations. Journal of mass spectrometry : JMS 20060301
Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily. Biochemistry 20060214
CFSUM1 and CFSUM2 in urine from patients with chronic fatigue syndrome are methodological artefacts. Clinica chimica acta; international journal of clinical chemistry 20060201
Impaired activity of the gamma-glutamyl cycle in nephropathic cystinosis fibroblasts. Pediatric research 20060201
Antioxidants as novel agents for asthma. Mini reviews in medicinal chemistry 20060201
Roles of N-terminal pyroglutamate in maintaining structural integrity and pKa values of catalytic histidine residues in bullfrog ribonuclease 3. Journal of molecular biology 20060120
Disruption of disulfide bond formation alters the trafficking of prothyrotropin releasing hormone (proTRH)-derived peptides. Regulatory peptides 20060115
Reversed-phase liquid chromatography/mass spectrometry analysis of reduced monoclonal antibodies in pharmaceutics. Journal of chromatography. A 20060113
Anatomy of the Hesse photoreceptor cell axonal system in the central nervous system of amphioxus. The Journal of comparative neurology 20060101
Allosteric control of an ionotropic glutamate receptor with an optical switch. Nature chemical biology 20060101
Proteome-level display by 2-dimensional chromatography of extracellular matrix-dependent modulation of the phenotype of bladder cancer cells. Proteome science 20060101
Microarray evidence of glutaminyl cyclase gene expression in melanoma: implications for tumor antigen specific immunotherapy. Journal of translational medicine 20060101
[Correlations of pharmacokinetics and pharmacodynamics of a combined preparation containing pyrrolidone and pyroglutamic acid]. Eksperimental'naia i klinicheskaia farmakologiia 20060101
Unmeasured anions in metabolic acidosis: unravelling the mystery. Critical care (London, England) 20060101
Day-night differences in membrane-bound pyroglutamyl-2-naphthylamide-hydrolyzing activity in rat hypothalamus, pituitary, and retina. Chronobiology international 20060101
Effect of pyrrolidone-pyroglutamic acid composition on blood flow in rat middle cerebral artery. Bulletin of experimental biology and medicine 20060101
Effects of glutathione supplementation during peritoneal dialysis. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20060101
Flight fuel and neuropeptidergic control of fuel mobilisation in the twig wilter, Holopterna alata (Hemiptera, Coreidae). Journal of insect physiology 20060101
Papaya glutamine cyclotransferase shows a singular five-fold beta-propeller architecture that suggests a novel reaction mechanism. Biological chemistry 20060101
Identification of N-terminal modification for recombinant monoclonal antibody light chain using partial reduction and quadrupole time-of-flight mass spectrometry. Rapid communications in mass spectrometry : RCM 20060101
[AMPK, an active player in the control of metabolism]. Journal de la Societe de biologie 20060101
A follow up study on the efficacy of metadoxine in the treatment of alcohol dependence. Substance abuse treatment, prevention, and policy 20060101
[Clinical trials of new therapeutic pharmacology for sickle cell disease]. Sante (Montrouge, France) 20060101
Structural conservation of mouse and rat zona pellucida glycoproteins. Probing the native rat zona pellucida proteome by mass spectrometry. Biochemistry 20051220
Altered glucose and insulin responses to brain medullary thyrotropin-releasing hormone (TRH)-induced autonomic activation in type 2 diabetic Goto-Kakizaki rats. Endocrinology 20051201
Molecular mechanisms during sperm capacitation. Human fertility (Cambridge, England) 20051201
[Adipocytokins, obesity and development of type 2 diabetes]. Medecine sciences : M/S 20051201
An efficient synthesis of the constrained peptidomimetic 2-oxo-3-(N-9-fluorenyloxycarbonylamino)-1-azabicyclo[4.3.0]nonane-9-carboxylic acid from pyroglutamic acid. The Journal of organic chemistry 20051125
[The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis]. Orvosi hetilap 20051120
Familial Danish dementia: co-existence of Danish and Alzheimer amyloid subunits (ADan AND A{beta}) in the absence of compact plaques. The Journal of biological chemistry 20051104
Michael addition reactions between chiral equivalents of a nucleophilic glycine and (S)- or (R)-3-[(E)-enoyl]-4-phenyl-1,3-oxazolidin-2-ones as a general method for efficient preparation of beta-substituted pyroglutamic acids. Case of topographically controlled stereoselectivity. Journal of the American Chemical Society 20051102
Thyrotropin-releasing hormone in the dorsal vagal complex stimulates pancreatic blood flow in rats. Regulatory peptides 20051101
A prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, regulates vascular permeability by reducing vascular endothelial growth factor expression in asthma. Molecular pharmacology 20051101
Virucidal hand treatments for prevention of rhinovirus infection. The Journal of antimicrobial chemotherapy 20051101
Intrathecally-administered histamine facilitates nociception through tachykinin NK1 and histamine H1 receptors: a study in histidine decarboxylase gene knockout mice. European journal of pharmacology 20051017
Firing pattern and rapid modulation of activity by estrogen in primate luteinizing hormone releasing hormone-1 neurons. Endocrinology 20051001
[Studies on chemical constituents in leaf of Isatis indigotica]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051001
Thermostability and in vitro digestibility of a purified major allergen 2S albumin (Ses i 1) from white sesame seeds (Sesamum indicum L.). Biochimica et biophysica acta 20050925
Synthesis of 1,3-dioxo-hexahydropyrido[1,2-c][1,3]diazepine carboxylates, a new bicyclic skeleton formed by ring expansion-RCM methodology. Chemical communications (Cambridge, England) 20050921
Functional characterisation of tachykinin receptors in the circular muscle layer of the mouse ileum. Regulatory peptides 20050915
Cloning, expression, characterization, and crystallization of a glutaminyl cyclase from human bone marrow: a single zinc metalloenzyme. Protein expression and purification 20050901
Central thyrotropin-releasing hormone increases hepatic cyclic AMP through vagal-cholinergic and prostaglandin-dependent pathways in rats. Peptides 20050901
Role of gastric mast cells in the regulation of central TRH analog-induced hyperemia in rats. Peptides 20050901
NC-1900, an arginine-vasopressin analogue, ameliorates social behavior deficits and hyperlocomotion in MK-801-treated rats: therapeutic implications for schizophrenia. Brain research 20050816
Stereoselective synthesis of conformationally constrained omega-amino acid analogues from pyroglutamic acid. Organic & biomolecular chemistry 20050807
Nanoparticles on the basis of highly functionalized dextrans. Journal of the American Chemical Society 20050803
Formation of extracellular glutamate from glutamine: exclusion of pyroglutamate as an intermediate. Brain research 20050802
Factor XIa dimer in the activation of factor IX. Biochemistry 20050802
Emerging roles of apelin in biology and medicine. Pharmacology & therapeutics 20050801
Effect of neurokinin-1 receptor antagonists on serotoninergic, noradrenergic and hippocampal neurons: comparison with antidepressant drugs. Peptides 20050801
Neuronal-glial plasticity in gonadotropin-releasing hormone release in adult female rats: role of the polysialylated form of the neural cell adhesion molecule. The Journal of endocrinology 20050801
Total synthesis of pinnamine and anatoxin-a via a common intermediate. A caveat on the anatoxin-a endgame. The Journal of organic chemistry 20050708
Identification of novel bradykinin-potentiating peptides and C-type natriuretic peptide from Lachesis muta venom. Toxicon : official journal of the International Society on Toxinology 20050701
The removal of pyroglutamic acid from monoclonal antibodies without denaturation of the protein chains. Analytical biochemistry 20050701
Recurrent high anion gap metabolic acidosis secondary to 5-oxoproline (pyroglutamic acid). American journal of kidney diseases : the official journal of the National Kidney Foundation 20050701
Acetaminophen-induced anion gap metabolic acidosis and 5-oxoprolinuria (pyroglutamic aciduria) acquired in hospital. American journal of kidney diseases : the official journal of the National Kidney Foundation 20050701
Aldosterone inhibits uncoupling protein-1, induces insulin resistance, and stimulates proinflammatory adipokines in adipocytes. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20050701
Total synthesis of cyclic tetrapeptide FR235222, a potent immunosuppressant that inhibits mammalian histone deacetylases. Organic letters 20050623
Substance P does not play a critical role in neurogenic inflammation in the rat masseter muscle. Brain research 20050614
Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes. Brain research. Molecular brain research 20050613
Urinary tract infection in children. Clinical evidence 20050601
Synthesis of 3'-deoxy-3'-difluoromethyl azanucleosides from trans-4-hydroxy-l-proline. The Journal of organic chemistry 20050513
The newly discovered insect order Mantophasmatodea contains a novel member of the adipokinetic hormone family of peptides. Biochemical and biophysical research communications 20050506
Activation of triacylglycerol lipase in the fat body of a beetle by adipokinetic hormone. Insect biochemistry and molecular biology 20050501
Glutamate antagonists attenuate the action of NC-1900, a vasopressin fragment analog, on passive avoidance task performance in mice. Peptides 20050501
Bromophenols coupled with derivatives of amino acids and nucleosides from the red alga Rhodomela confervoides. Journal of natural products 20050501
Phorbol ester up-regulates aldose reductase expression in A549 cells: a potential role for aldose reductase in cell cycle modulation. Cellular and molecular life sciences : CMLS 20050501
Chronic ethanol or glucose consumption alter TRH content and pyroglutamyl aminopeptidase II activity in rat limbic regions. Regulatory peptides 20050415
Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection. American journal of physiology. Lung cellular and molecular physiology 20050401
Anuroctoxin, a new scorpion toxin of the alpha-KTx 6 subfamily, is highly selective for Kv1.3 over IKCa1 ion channels of human T lymphocytes. Molecular pharmacology 20050401
Quantification of cell-cycle distribution and mitotic index in Hydra by flow cytometry. Cell proliferation 20050401
Application of stability-indicating HPTLC method for quantitative determination of metadoxine in pharmaceutical dosage form. Farmaco (Societa chimica italiana : 1989) 20050401
Glutamatergic innervation of corticotropin-releasing hormone- and thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus of the rat. Brain research 20050328
Air-stable Ir-(P-Phos) complex for highly enantioselective hydrogenation of quinolines and their immobilization in poly(ethylene glycol) dimethyl ether (DMPEG). Chemical communications (Cambridge, England) 20050321
Straightforward ring expansion of pyroglutamates to perhydro-1,3-diazepine-2,4-diones. Organic letters 20050317
Gln-tRNAGln formation from Glu-tRNAGln requires cooperation of an asparaginase and a Glu-tRNAGln kinase. The Journal of biological chemistry 20050304
Preparation and reactivity of aminoacyl pyroglutamates. Facile synthesis of 10-membered-ring cyclic dipeptides derived from 1,4-diaminobutyric and glutamic acids. Journal of peptide science : an official publication of the European Peptide Society 20050301
Importance of the central region of lamprey gonadotropin-releasing hormone III in the inhibition of breast cancer cell growth. Peptides 20050301
Acute administration of alcohol modulates pyroglutamyl amino peptidase II activity and mRNA levels in rat limbic regions. Neurochemistry international 20050301
A pyridinium-substituted analog of the TRH-like tripeptide pGlu-Glu-Pro-NH2 and its prodrugs as central nervous system agents. Medicinal chemistry (Shariqah (United Arab Emirates)) 20050301
Degradation, insulin secretion, and antihyperglycemic actions of two palmitate-derivitized N-terminal pyroglutamyl analogues of glucose-dependent insulinotropic polypeptide. Journal of medicinal chemistry 20050224
Protective effect of central thyrotropin-releasing hormone analog on cerulein-induced acute pancreatitis in rats. Regulatory peptides 20050215
AKH-producing neuroendocrine cell ablation decreases trehalose and induces behavioral changes in Drosophila. American journal of physiology. Regulatory, integrative and comparative physiology 20050201
Evaluation of early gastric mucosal permeability induced by central thyrotropin-releasing hormone administration. American journal of physiology. Gastrointestinal and liver physiology 20050201
A truncated isoform of pyroglutamyl aminopeptidase II produced by exon extension has dominant-negative activity. Journal of neurochemistry 20050201
Magnesium as a treatment for paediatric tension-type headache: a clinical replication series. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20050201
First messenger regulation of mammalian sperm function via adenylyl cyclase/cAMP. The Journal of reproduction and development 20050201
Physiological and pathological aspects of GSH metabolism. Acta paediatrica (Oslo, Norway : 1992) 20050201
The computer modelling of human TRH receptor, TRH and TRH-like peptides. Physiological research 20050101
Severe hyperhomocysteinaemia and 5-oxoprolinuria secondary to antiproliferative and antimicrobial drug treatment. Journal of inherited metabolic disease 20050101
A high-throughput liquid chromatography/tandem mass spectrometry method for screening glutathione conjugates using exact mass neutral loss acquisition. Rapid communications in mass spectrometry : RCM 20050101
Biomarker metabolites capturing the metabolite variance present in a rice plant developmental period. BMC plant biology 20050101
CLPM: a cross-linked peptide mapping algorithm for mass spectrometric analysis. BMC bioinformatics 20050101
Trial of erythropoietin treatment in a boy with glutathione synthetase deficiency. Journal of inherited metabolic disease 20050101
[Role of metadoxyl in the treatment of the hepatotoxic effects of cytostatics]. Voprosy onkologii 20050101
An active insect kinin analog with 4-aminopyroglutamate, a novel cis-peptide bond, type VI beta-turn motif. Biopolymers 20041205
Infusion of the substance P analogue, DiMe-C7, into the ventral tegmental area induces reinstatement of cocaine-seeking behaviour in rats. Psychopharmacology 20041201
Blockade of airway hyperresponsiveness and inflammation in a murine model of asthma by a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041201
L-2-oxothiazolidine-4-carboxylic acid reduces in vitro cytotoxicity of glucose degradation products. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041201
Endopeptidase activity of larval Lacanobia oleracea corpus allatum: metabolism of Manduca sexta allatostatin and allatotropin. Archives of insect biochemistry and physiology 20041201
Regulation of interleukin-6 expression by arecoline in human buccal mucosal fibroblasts is related to intracellular glutathione levels. Oral diseases 20041101
Diastereoselective syntheses of deoxydysibetaine, dysibetaine, and its 4-epimer. The Journal of organic chemistry 20041029
Alpha-tocopherol pro-vitamins: synthesis, hydrolysis and accumulation in rabbit ear skin. Journal of controlled release : official journal of the Controlled Release Society 20041019
Discrepin, a new peptide of the sub-family alpha-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K+ -channels (IA currents) of cerebellum granular cells. Archives of biochemistry and biophysics 20041015
Further evidence on the anxiogenic-like effect of substance P evaluated in the elevated plus-maze in rats. Behavioural brain research 20041005
Sequence and expression of the CAPA/CAP2b gene in the tobacco hawkmoth, Manduca sexta. The Journal of experimental biology 20041001
Mass spectrometry analysis of recombinant human ZP3 expressed in glycosylation-deficient CHO cells. Biochemistry 20040928
The development of a higher throughput reactive intermediate screening assay incorporating micro-bore liquid chromatography-micro-electrospray ionization-tandem mass spectrometry and glutathione ethyl ester as an in vitro conjugating agent. Journal of pharmaceutical and biomedical analysis 20040921
Conserved mechanisms of glucose sensing and regulation by Drosophila corpora cardiaca cells. Nature 20040916
Obligatory involvement of CD26/dipeptidyl peptidase IV in the activation of the antiretroviral tripeptide glycylprolylglycinamide (GPG-NH(2)). The international journal of biochemistry & cell biology 20040901
Isolation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions. Cancer science 20040901
Glutamine in commercial liquid nutritional products. Journal of agricultural and food chemistry 20040811
Pyroglutamyl-asparagine amide normalizes long-term potentiation in rat hippocampal slices. Bulletin of experimental biology and medicine 20040801
Virtually complete control of simple and face diastereoselectivity in the Michael addition reactions between achiral equivalents of a nucleophilic glycine and (S)- or (R)-3-(E-enoyl)-4-phenyl-1,3-oxazolidin-2-ones: practical method for preparation of beta-substituted pyroglutamic acids and prolines. The Journal of organic chemistry 20040723
[Antioxidants in liver protection]. Orvosi hetilap 20040704
Facilitative effect of a novel AVP fragment analog, NC-1900, on memory retention and recall in mice. Peptides 20040701
15Alpha-hydroxyprogesterone in male sea lampreys, Petromyzon marinus L. Steroids 20040701
[Study on the mechanism of male reproductive toxicity of metadoxine in mice and rats]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20040701
Circadian rhythm of pigment migration induced by chromatrophorotropins in melanophores of the crab Chasmagnathus granulata. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20040701
Preventive effect of antioxidants in MPTP-induced mouse model of Parkinson's disease. Neuroscience letters 20040617
Allosteric modification of factor XIa functional activity upon binding to polyanions. Biochemistry 20040615
Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS biology 20040601
Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder. The American journal of psychiatry 20040601
Effect of pretraining administration of NC-1900, a vasopressin fragment analog, on memory performance in non- or CO2-amnesic mice. Pharmacology, biochemistry, and behavior 20040601
Mass spectrometric analysis of posttranslational modifications of a carrot extracellular glycoprotein. Biochemistry 20040525
GABAergic basal forebrain neurons that express receptor for neurokinin B and send axons to the cerebral cortex. The Journal of comparative neurology 20040517
Spawning and gamete follicle rupture in the cnidarian Renilla koellikeri: effects of putative neurohormones. General and comparative endocrinology 20040515
Synthesis of (2S,3R)-[3',3',3'-2H3]-valine and (2S,3S)-4-fluorovaline. Organic & biomolecular chemistry 20040507
Hemolymph sugar homeostasis and starvation-induced hyperactivity affected by genetic manipulations of the adipokinetic hormone-encoding gene in Drosophila melanogaster. Genetics 20040501
Origin of diastereoselection in the hydrosilylation of chiral N-acyliminium intermediates derived from pyroglutamic acid. Angewandte Chemie (International ed. in English) 20040426
Application of intramolecular enyne metathesis to the synthesis of aza[4.2.1]bicyclics: enantiospecific total synthesis of (+)-anatoxin-a. Organic letters 20040415
Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions. FEBS letters 20040409
15alpha-hydroxytestosterone induction by GnRH I and GnRH III in Atlantic and Great Lakes sea lamprey (Petromyzon marinus L.). General and comparative endocrinology 20040401
The first total synthesis of a pyranonaphthoquinone antitumor, BE-54238B. The Journal of antibiotics 20040401
Synthesis of (2S,3S)-3'-fluoroisoleucine. Organic & biomolecular chemistry 20040307
Central administration of cocaine- and amphetamine-regulated transcript increases phosphorylation of cAMP response element binding protein in corticotropin-releasing hormone-producing neurons but not in prothyrotropin-releasing hormone-producing neurons in the hypothalamic paraventricular nucleus. Brain research 20040305
Unexplained metabolic acidosis in critically ill patients: the role of pyroglutamic acid. Intensive care medicine 20040301
Bovine 5-oxo-L-prolinase: simple assay method, purification, cDNA cloning, and detection of mRNA in the coronary artery. Biological & pharmaceutical bulletin 20040301
Human sperm responses to calcitonin, angiotensin II and fertilization-promoting peptide in prepared semen samples from normal donors and infertility patients. Human reproduction (Oxford, England) 20040301
N-terminal His(7)-modification of glucagon-like peptide-1(7-36) amide generates dipeptidyl peptidase IV-stable analogues with potent antihyperglycaemic activity. The Journal of endocrinology 20040301
Chemical characterization of a lambda I amyloid protein isolated from formalin-fixed and paraffin-embedded tissue sections. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20040301
Identification of endogenous phosphorylation sites of bovine medium and low molecular weight neurofilament proteins by tandem mass spectrometry. Biochemistry 20040224
Expression, purification, and characterization of avian Thy-1 from Lec1 mammalian and Tn5 insect cells. Protein expression and purification 20040201
Stabilization of peptide guinea pig myelin basic protein 72-85 by N-terminal acetylation-implications for immunological studies. Molecular immunology 20040201
Toward the synthesis of pyroglutamate lauroyl ester: biocatalysis versus chemical catalysis. Biotechnology letters 20040201
Purification of a specific inhibitor of pyroglutamyl aminopeptidase II from the marine annelide Hermodice carunculata. in vivo effects in rodent brain. The international journal of biochemistry & cell biology 20040101
Regulation of intermediary metabolism and water balance of insects by neuropeptides. Annual review of entomology 20040101
N-acetylation of the glutamate residue of intact glutathione conjugates in rats: a novel pathway for the metabolic processing of thiol adducts of xenobiotics. Drug metabolism and disposition: the biological fate of chemicals 20040101
Pyroglutamyl aminopeptidase I, as a drug metabolizing enzyme, recognizes xenobiotic substrates containing L-2-oxothiazolidine-4-carboxylic acid. Biological & pharmaceutical bulletin 20040101
Stimulatory effect of PG-KII, an NK3 tachykinin receptor agonist, on isolated pancreatic acini: species-related differences. Peptides 20040101
Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site. BMC biology 20040101
Catalytic hydrogenation of glutamic acid. Applied biochemistry and biotechnology 20040101
Evidence that lamprey GnRH-III does not release FSH selectively in cattle. Reproduction (Cambridge, England) 20040101
A newborn infant with generalized glutathione synthetase deficiency. The Turkish journal of pediatrics 20040101
Preventing the spontaneous modification of an HLA-A2-restricted peptide at an N-terminal glutamine or an internal cysteine residue enhances peptide antigenicity. Journal of immunotherapy (Hagerstown, Md. : 1997) 20040101
Skin secretion of the toad Bombina variegata contains multiple insulin-releasing peptides including bombesin and entirely novel insulinotropic structures. Biological chemistry 20040101
The colon mitosis inhibitor pyroglutamyl-histidyl-glycine inhibits growth of non-tumorigenic colonic epithelial cells. Anticancer research 20040101
Immune modulator pidotimod decreases the in vitro expression of CD30 in peripheral blood mononuclear cells of atopic asthmatic and normal children. The Journal of asthma : official journal of the Association for the Care of Asthma 20040101
Pyroglutamyl-histidyl-glycine, the endogenous colon mitosis inhibitor, regulates cyclic AMP level in non-tumorigenic colonic epithelial cells. Anticancer research 20040101
[Antioxidants-induced rearrangements of actin cytoskeleton in 3T3 and 3T3-SV40 fibroblasts]. Tsitologiia 20040101
3,3',5'-triiodo-L-thyronine reduces efficiency of mRNA knockdown by antisense oligodeoxynucleotides: a study with pyroglutamyl aminopeptidase II in adenohypophysis. Oligonucleotides 20040101
Pressure/temperature combined treatments of precursors yield hormone-like peptides with pyroglutamate at the N terminus. Journal of agricultural and food chemistry 20031231
First messenger regulation of capacitation via G protein-coupled mechanisms: a tale of serendipity and discovery. Molecular human reproduction 20031201
Thyrotropin-releasing hormone in the dorsal vagal complex stimulates hepatic blood flow in rats. Hepatology (Baltimore, Md.) 20031201
Characterization of a circulating N-extended form of the thyrotropin-releasing hormone-like peptide pGlu-Glu-Pro amide in human plasma. The Journal of clinical endocrinology and metabolism 20031201
Substrate specificity of glutaminyl cyclases from plants and animals. Biological chemistry 20031201
Effect of chirality on the structural behaviour of hydrogen-bonded n-alkylammonium pyroglutamates in the crystalline and smectic state. Chemistry (Weinheim an der Bergstrasse, Germany) 20031107
Glucose acts in the CNS to regulate gastric motility during hypoglycemia. American journal of physiology. Regulatory, integrative and comparative physiology 20031101
Hydrolysis of synthetic substrate, L-pyroglutamyl p-nitroanilide is catalyzed solely by pyroglutamyl aminopeptidase I in rat liver cytosol. Biological & pharmaceutical bulletin 20031101
Chemoselective nucleophilic attack on N-acyl derivatives of (S)-ethyl 4,4-dimethyl pyroglutamate (DMPG). Organic letters 20031016
Involvement of calcitonin gene-related peptide and capsaicin-sensitive afferents in central thyrotropin-releasing hormone-induced hepatic cytoprotection. European journal of pharmacology 20031008
Adipokinetic hormone inhibits the formation of energy stores and egg production in the cricket Gryllus bimaculatus. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20031001
Structural characterization of native mouse zona pellucida proteins using mass spectrometry. The Journal of biological chemistry 20030905
Intracellular mediators of granulysin-induced cell death. Journal of immunology (Baltimore, Md. : 1950) 20030901
Refolding of amphioxus insulin-like peptide: implications of a bifurcating evolution of the different folding behavior of insulin and insulin-like growth factor 1. Biochemistry 20030819
Pigment-epithelium-derived factor (PEDF) occurs at a physiologically relevant concentration in human blood: purification and characterization. The Biochemical journal 20030815
Beta-lactams as versatile synthons for homochiral ibotenate analogues with potential for activity at glutamate receptors. Organic & biomolecular chemistry 20030807
Peristalsis regulation by tachykinin NK1 receptors in the rabbit isolated distal colon. American journal of physiology. Gastrointestinal and liver physiology 20030801
Fibrosis and glycogen stores depletion induced by prolonged biliary obstruction in the rat are ameliorated by metadoxine. Liver international : official journal of the International Association for the Study of the Liver 20030801
Pyrrolidinones derived from (S)-pyroglutamic acid: penmacric acid and analogues. Organic & biomolecular chemistry 20030707
Protective effect of central thyrotropin-releasing hormone on carbon tetrachloride-induced acute hepatocellular necrosis in rats. Journal of hepatology 20030701
Characterization of a new bradykinin-potentiating peptide (TmF) from Trimeresurus mucrosquamatus. Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20030701
Effect of pyroglutamylasparagine amide on plastic characteristics of synaptic transmission in the hippocampus. Bulletin of experimental biology and medicine 20030701
2,5-Disubstituted pyrrolidines: versatile regioselective and diastereoselective synthesis by enamine reduction and subsequent alkylation. Organic & biomolecular chemistry 20030607
L-2-oxothiazolidine-4-carboxylate supplementation in murine gamma-GT deficiency. Free radical biology & medicine 20030601
Mode of action of neuropeptides from the adipokinetic hormone family. General and comparative endocrinology 20030601
Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules. Metabolism: clinical and experimental 20030601
Comparison of structure-activity relations of corazonin using two different bioassay systems. Peptides 20030601
Intravenous urocortin II decreases blood pressure through CRF(2) receptor in rats. Regulatory peptides 20030515
Synthesis of cis-4-trifluoromethyl- and cis-4-difluoromethyl-l-pyroglutamic acids. The Journal of organic chemistry 20030502
Proinsulin C-peptide and its C-terminal pentapeptide: degradation in human serum and Schiff base formation with subsequent CO2 incorporation. Cellular and molecular life sciences : CMLS 20030501
[Reproductive toxicity of metadoxine in rats]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20030501
[Oleyl pyroglutamate for use as transdermal enhancer and its enhancing mechanism]. Yao xue xue bao = Acta pharmaceutica Sinica 20030501
Inhibitory effect of L-pyroglutamate on extremophiles: correlation with growth temperature and pH. FEMS microbiology letters 20030425
Central administration of thyrotropin releasing hormone (TRH) and related peptides inhibits feeding behavior in the Siberian hamster. Neuroreport 20030415
Intravenous glucose infusion decreases intracisternal thyrotropin-releasing hormone induced vagal stimulation of gastric acid secretion in anesthetized rats. Neuroscience letters 20030403
Oxothiazolidine carboxylate provides protection against hepatocellular injury seen after porta hepatis occlusion (Pringle maneuver) under hypovolemic conditions. World journal of surgery 20030401
[Advances in modulation of mammalian sperm function by fertilization promoting peptide]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20030401
Characterization and sequence of tomato 2S seed albumin: a storage protein with sequence similarities to the fruit lectin. Planta 20030401
Biologic activity of the tachykinins on lamb and sheep gallbladder. Peptides 20030401
Determination of the post-translational modifications of salivary acidic proline-rich proteins. European journal of morphology 20030401
Prodrugs to enhance central nervous system effects of the TRH-like peptide pGlu-Glu-Pro-NH2. Bioorganic & medicinal chemistry letters 20030324
Synthesis and reactions of a novel 3,4-didehydropyroglutamate derivative. Chemical communications (Cambridge, England) 20030321
Development and conformational analysis of a pseudoproline-containing turn mimic. The Journal of organic chemistry 20030307
The up-regulation of cyclooxygenase-2 expression in human buccal mucosal fibroblasts by arecoline: a possible role in the pathogenesis of oral submucous fibrosis. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20030301
In vitro metabolism of an insect neuropeptide by homogenates of the nematode Caenorhabditis elegans. Journal of helminthology 20030301
Reinvestigation of the proposed folding and self-association of the Neuropeptide Head Activator. Protein science : a publication of the Protein Society 20030301
Ameliorative effect of NC-1900, a new AVP4-9 analog, through vasopressin V1A receptor on scopolamine-induced impairments of spatial memory in the eight-arm radial maze. Neuropharmacology 20030301
Solution structure of the cytotoxic RNase 4 from oocytes of bullfrog Rana catesbeiana. Journal of molecular biology 20030227
Lafutidine increases hepatic blood flow via potentiating the action of central thyrotropin-releasing hormone in rats. Journal of gastroenterology and hepatology 20030201
Induction of c-fos expression by nicotine in human periodontal ligament fibroblasts is related to cellular thiol levels. Journal of periodontal research 20030201
Intrathecal histamine induces spinally mediated behavioral responses through tachykinin NK1 receptors. Pharmacology, biochemistry, and behavior 20030101
Central administration of neuropeptide Y reduces alpha-melanocyte-stimulating hormone-induced cyclic adenosine 5'-monophosphate response element binding protein (CREB) phosphorylation in pro-thyrotropin-releasing hormone neurons and increases CREB phosphorylation in corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology 20030101
Deblocking of N-terminally modified proteins. Methods in molecular biology (Clifton, N.J.) 20030101
Isolation and identification of indigestible pyroglutamyl peptides in an enzymatic hydrolysate of wheat gluten prepared on an industrial scale. Journal of agricultural and food chemistry 20030101
Effects of fertilization promoting peptide, adenosine, and pentoxifylline on thawed human sperm. Archives of andrology 20030101
[Neuroprotective properties of pyroglutamic acid in combination with pyrrolidone]. Eksperimental'naia i klinicheskaia farmakologiia 20030101
[Effect of agents changing the intracellular level of reactive oxygen species on the cell cycle phase distribution in 3T3 and 3T3SV40 cell lines]. Tsitologiia 20030101
The colon mitosis-inhibitor pyroglutamyl-histidyl-glycine alters expression of immediate-early cancer-related genes in HT-29 cells. Anticancer research 20030101
[Evolution of the neuroprotection concept]. Eksperimental'naia i klinicheskaia farmakologiia 20030101
[Neuroprotective and cerebrovascular effects of GABA mimetics]. Eksperimental'naia i klinicheskaia farmakologiia 20030101
Glucose-induced changes in the phenotype of human peritoneal mesothelial cells: effect of L-2-oxothiazolidine carboxylic acid. American journal of nephrology 20030101
Characterizing degradation products of peptides containing N-terminal Cys residues by (off-line high-performance liquid chromatography)/matrix-assisted laser desorption/ionization quadrupole time-of-flight measurements. Rapid communications in mass spectrometry : RCM 20030101
Metadoxine in the treatment of acute and chronic alcoholism: a review. International journal of immunopathology and pharmacology 20030101
[Therapy with cytokines and thymic factors in a complicated case of common variable immunodeficiency]. Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20030101
A new approach to drug therapy in non-alcoholic steatohepatitis (NASH). The Journal of international medical research 20030101
[Characteristics of pyrrolidone pharmacokinetics in rats]. Eksperimental'naia i klinicheskaia farmakologiia 20030101
[The correlation of tolerance to cerebral ischemia and body temperature with glutathione concentration]. Biomeditsinskaia khimiia 20030101
Cocaine regulates TRH-related peptides in rat brain. Neurochemistry international 20021201
The role of Ins(1,4,5)P(3) in signal transduction of the metabolic neuropeptide Mem-CC in the cetoniid beetle, Pachnoda sinuata. Insect biochemistry and molecular biology 20021201
Synthesis and preliminary evaluation of trans-3,4-conformationally-restricted glutamate and pyroglutamate analogues as novel EAAT2 inhibitors. Bioorganic & medicinal chemistry letters 20021104
Leptin regulates bone formation via the sympathetic nervous system. Cell 20021101
Fluorometric assay using naphthylamide substrates for assessing novel venom peptidase activities. Toxicon : official journal of the International Society on Toxinology 20021101
Sensitivity of larval and adult crickets (Gryllus bimaculatus) to adipokinetic hormone. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20021101
Neuropharmacodynamic evaluation of the centrally active thyrotropin-releasing hormone analogue [Leu2]TRH and its chemical brain-targeting system. Brain research 20021018
Lamprey GnRH-III acts on its putative receptor via nitric oxide to release follicle-stimulating hormone specifically. Experimental biology and medicine (Maywood, N.J.) 20021001
Activation of raphe pallidus neurons increases insulin through medullary thyrotropin-releasing hormone (TRH)-vagal pathways. Pancreas 20021001
Production of pyroglutamic acid by thermophilic lactic acid bacteria in hard-cooked mini-cheeses. Journal of dairy science 20021001
Stereoselective synthesis of dipeptide beta-turn mimetics: 7-benzyl and 8-phenyl substituted azabicyclo[4.3.0]nonane amino acid esters. The Journal of organic chemistry 20020906
Heterologous expression and characterization of human glutaminyl cyclase: evidence for a disulfide bond with importance for catalytic activity. Biochemistry 20020903
In vivo monitoring of hepatic glutathione in anesthetized rats by 13C NMR. Magnetic resonance in medicine 20020901
Thyrotropin-releasing hormone regulates the diurnal variation of pyroglutamyl aminopeptidase II activity in the male rat adenohypophysis. European journal of endocrinology 20020901
Pyroglutamate-modified amyloid beta-peptides--AbetaN3(pE)--strongly affect cultured neuron and astrocyte survival. Journal of neurochemistry 20020901
Inhibition of aldose reductase enhances HeLa cell sensitivity to chemotherapeutic drugs and involves activation of extracellular signal-regulated kinases. Anti-cancer drugs 20020901
Complete structure of an increasing capillary permeability protein (ICPP) purified from Vipera lebetina venom. ICPP is angiogenic via vascular endothelial growth factor receptor signalling. The Journal of biological chemistry 20020816
Clinical evaluation and changes of the respiratory epithelium function after administration of Pidotimod in Greek children with recurrent respiratory tract infections. Minerva pediatrica 20020801
Transmitting the signal of excess nitrogen in Saccharomyces cerevisiae from the Tor proteins to the GATA factors: connecting the dots. FEMS microbiology reviews 20020801
Effects of dietary cholesterol on pyroglutamyl aminopeptidase activity in mouse frontal cortex, pituitary, and adrenal glands. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020801
Mechanisms of cytotoxicity of nicotine in human periodontal ligament fibroblast cultures in vitro. Journal of periodontal research 20020801
Effect of a fertilization-promoting peptide on the fertilizing ability and glycosidase activity in vitro of frozen-thawed spermatozoa in the pig. Animal reproduction science 20020715
Generation of amyloid beta peptide with pyroglutamate at position 3 in primary cortical neurons. Neuroscience letters 20020712
Two novel antifungal peptides distinct with a five-disulfide motif from the bark of Eucommia ulmoides Oliv. FEBS letters 20020619
Determination of the absolute configuration of 2-hydroxyglutaric acid and 5-oxoproline in urine samples by high-resolution NMR spectroscopy in the presence of chiral lanthanide complexes. Journal of pharmaceutical and biomedical analysis 20020615
Pharmacologically distinct binding sites in rat brain for [3H]thyrotropin-releasing hormone (TRH) and [3H][3-methyl-histidine(2)]TRH. Biochemical pharmacology 20020615
Stereoselective total syntheses of the racemic form and the natural enantiomer of the marine alkaloid lepadiformine via a novel N-acyliminium ion/allylsilane spirocyclization strategy. The Journal of organic chemistry 20020614
Spinal nociceptin inhibits septide but not N-methyl-D-aspartate-induced nociceptive behavior in rats. European journal of pharmacology 20020607
Pseudopeptide foldamers: the homo-oligomers of pyroglutamic acid. Chemistry (Weinheim an der Bergstrasse, Germany) 20020603
A possible molecular ancestor for mollusk APGWamide, insect adipokinetic hormone, and crustacean red pigment concentrating hormone. Journal of molecular evolution 20020601
Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues. European journal of biochemistry 20020601
Synthesis and biological evaluation of a novel pyroglutamyl-modified TRH analogue. Farmaco (Societa chimica italiana : 1989) 20020601
Allatostatins of the tiger prawn, Penaeus monodon (Crustacea: Penaeidea). Peptides 20020601
Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science (New York, N.Y.) 20020510
Role of TRH receptors as possible mediators of analeptic actions of TRH-like peptides. Brain research 20020510
Beetles' choice--proline for energy output: control by AKHs. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020501
Selective tachykinin NK3-receptor agonists stimulate in vitro exocrine pancreatic secretion in the guinea pig. Peptides 20020501
Spectrophotometric assays for L-lysine alpha-oxidase and gamma-glutamylamine cyclotransferase. Analytical biochemistry 20020415
CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV. The EMBO journal 20020402
New insights in Adipokinetic Hormone (AKH) precursor processing in Locusta migratoria obtained by capillary liquid chromatography-tandem mass spectrometry. Peptides 20020401
Major outer membrane proteins and proteolytic processing of RgpA and Kgp of Porphyromonas gingivalis W50. The Biochemical journal 20020401
Dietary fatty acid composition affects aminopeptidase activities in the testes of mice. International journal of andrology 20020401
Continuous spectrometric assays for glutaminyl cyclase activity. Analytical biochemistry 20020401
Inhibition of contact hypersensitivity reaction to picryl chloride: effect of small molecular weight peptidomimetic compounds possessing inhibitory activity against metalloproteinases. International immunopharmacology 20020401
Five- and six-membered ring opening of pyroglutamic diketopiperazine. The Journal of organic chemistry 20020322
Facilitation by endogenous tachykinins of the NMDA-evoked release of acetylcholine after acute and chronic suppression of dopaminergic transmission in the matrix of the rat striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301
Metadoxine in acute alcohol intoxication: a double-blind, randomized, placebo-controlled study. Alcoholism, clinical and experimental research 20020301
Thyrotropin-releasing hormone-induced down-regulation of pyroglutamyl aminopeptidase II activity involves L-type calcium channels and cam kinase activities in cultures of adenohypophyseal cells. Journal of neuroendocrinology 20020301
Aminopeptidases in Caenorhabditis elegans and Panagrellus redivivus: detection using peptide and non-peptide substrates. Journal of helminthology 20020301
Antidiabetic effect of a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, through CD38 dimerization and internalization. The Journal of biological chemistry 20020215
Conformationally restricted TRH analogues: constraining the pyroglutamate region. Bioorganic & medicinal chemistry 20020201
Plasma L-5-oxoproline kinetics and whole blood glutathione synthesis rates in severely burned adult humans. American journal of physiology. Endocrinology and metabolism 20020201
L-2-Oxothiazolidine-4-carboxylate reverses the tumour growth-promoting effect of interleukin-2 and improves the anti-tumour efficacy of biochemotherapy in mice bearing B16 melanoma liver metastases. Melanoma research 20020201
Purification and characterization of the thyrotropin-releasing hormone (TRH)-degrading serum enzyme and its identification as a product of liver origin. European journal of biochemistry 20020201
In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice. Archives of biochemistry and biophysics 20020115
Permissive role of neurokinin NK(3) receptors in NK(1) receptor-mediated activation of the locus coeruleus revealed by SR 142801. Synapse (New York, N.Y.) 20020101
Molecular characterization of the TCP11 gene which is the human homologue of the mouse gene encoding the receptor of fertilization promoting peptide. Molecular human reproduction 20020101
Cellular redox state and endothelial dysfunction in mildly hyperhomocysteinemic cystathionine beta-synthase-deficient mice. Arteriosclerosis, thrombosis, and vascular biology 20020101
Comparison of the positive and negative ion electrospray mass spectra of some small peptides containing pyroglutamate. Rapid communications in mass spectrometry : RCM 20020101
Rapid determination of underivatized pyroglutamic acid, glutamic acid, glutamine and other relevant amino acids in fermentation media by LC-MS-MS. The Analyst 20020101
The primary structure of cassowary (Casuarius casuarius) goose type lysozyme. Bioscience, biotechnology, and biochemistry 20020101
Efficacy of metadoxine in the management of acute alcohol intoxication. The Journal of international medical research 20020101
[Polar constituents of the ascidia Botryllus schlosseri]. Bioorganicheskaia khimiia 20020101
Selective hypersensitivity to pidolate. Allergy 20020101
Early oncogene mRNA expression in HT-29 cells treated with the endogenous colon mitosis inhibitor pyroglutamyl-histidyl-glycine. Anticancer research 20020101
[Sterility of males determined by functional features of the mouse spermatozoa bearing t-complex]. Ontogenez 20020101
[Pidotimod in recurring respiratory infection in children with allergic rhinitis, asthma, or both conditions]. Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20020101
[Effect of a drug composition containing pyroglutamic acid and pyrrolidone on the cerebral circulation]. Eksperimental'naia i klinicheskaia farmakologiia 20020101
L-2-oxothiazolidine-4-carboxylate: an agent that modulates lipopolysaccharide-induced peritonitis in rats. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20020101
Synthesis of ( 2S, 4S)-4-phenylamino-5-oxoproline derivatives. Amino acids 20020101
Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status. Redox report : communications in free radical research 20020101
Use of sodium borohydride to detect acyl-phosphate linkages in enzyme reactions. Methods in enzymology 20020101
[Glutathione in therapy]. Postepy higieny i medycyny doswiadczalnej 20020101
Methacrylate derivatives incorporating pyroglutamic acid. Biomacromolecules 20020101
Expression and prognostic significance of lysozyme in male breast cancer. Breast cancer research : BCR 20020101
[Organic acid disorders: cerebral organic acidemia]. Ryoikibetsu shokogun shirizu 20020101
The X-ray crystal structure of pyrrolidone-carboxylate peptidase from hyperthermophilic archaea Pyrococcus horikoshii. Journal of structural and functional genomics 20020101
Electrophilic fluorination of pyroglutamic acid derivatives: application of substrate-dependent reactivity and diastereoselectivity to the synthesis of optically active 4-fluoroglutamic acids. The Journal of organic chemistry 20011228
Hormonal stimulation of proline synthesis in the fat body of the fruit beetle, Pachnoda sinuata, is calcium dependent. Insect biochemistry and molecular biology 20011201
Recombinant wheat antifungal PR4 proteins expressed in Escherichia coli. Protein expression and purification 20011201
In vitro neuroprotection against glutamate-induced toxicity by pGlu-Glu-Pro-NH(2) (EEP). Peptides 20011201
Chromosome 13 dementia syndromes as models of neurodegeneration. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20011201
(L)-2-oxothiazolidine-4-carboxylate in the treatment of primary hyperoxaluria type 1. BJU international 20011201
L-pyroglutamic acid inhibits energy production and lipid synthesis in cerebral cortex of young rats in vitro. Neurochemical research 20011201
Efferent projections of ProTRH neurons in the ventrolateral periaqueductal gray. Brain research 20011123
Metadoxine prevents damage produced by ethanol and acetaldehyde in hepatocyte and hepatic stellate cells in culture. Pharmacological research 20011101
The neuropeptide head activator induces activation and translocation of the growth-factor-regulated Ca(2+)-permeable channel GRC. Journal of cell science 20011001
Strain-based sequence variations and structure analysis of murine prostate specific spermine binding protein using mass spectrometry. Biochemistry 20010814
Synthesis of lipids in the fat body of Gryllus bimaculatus: age-dependency and regulation by adipokinetic hormone. Archives of insect biochemistry and physiology 20010801
Modulators with convergent cellular actions elicit distinct circuit outputs. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601
Priming effects of substance P on calcium changes evoked by interleukin-8 in human neutrophils. Journal of leukocyte biology 20010601
Stability and CTL activity of N-terminal glutamic acid containing peptides. The journal of peptide research : official journal of the American Peptide Society 20010601
Massive 5-oxoprolinuria with normal 5-oxoprolinase and glutathione synthetase activities. Journal of inherited metabolic disease 20010601
Red pigment-concentrating hormone induces a calcium-mediated retraction of distal retinal pigments in the crayfish. Journal of comparative physiology. A, Sensory, neural, and behavioral physiology 20010601
The mechanism of aubstrate eecognition of pyroglutamyl-peptidase I from Bacillus amyloliquefaciens as determined by X-ray crystallography and site-directed mutagenesis. The Journal of biological chemistry 20010525
Inhibition of Escherichia coli CTP synthase by glutamate gamma-semialdehyde and the role of the allosteric effector GTP in glutamine hydrolysis. The Biochemical journal 20010515
Intracisternal TRH analog induces Fos expression in gastric myenteric neurons and glia in conscious rats. American journal of physiology. Gastrointestinal and liver physiology 20010501
Removal of N-terminal blocking groups from proteins. Current protocols in protein science 20010501
Effect of high population density environment on skin barrier function in mice. Journal of dermatological science 20010401
Rapid down regulation of pyroglutamyl peptidase II activity by arachidonic acid in primary cultures of adenohypophyseal cells. Life sciences 20010316
Potent cytolytic response by a CD8+ CTL clone to multiple peptides from the same protein in association with an allogeneic class I MHC molecule. Journal of immunology (Baltimore, Md. : 1950) 20010301
Calcitonin, angiotensin II and FPP significantly modulate mouse sperm function. Molecular human reproduction 20010301
Monoamine release by neurons of a primitive nervous system: an amperometric study. Journal of neurochemistry 20010301
Conformational study of insect adipokinetic hormones using NMR constrained molecular dynamics. Journal of computer-aided molecular design 20010301
Characterization of cigar tobaccos by gas chromatographic/mass spectrometric analysis of nonvolatile organic acids: application to the authentication of Cuban cigars. Journal of agricultural and food chemistry 20010301
Regulatory responses to an oral D-glutamate load: formation of D-pyrrolidone carboxylic acid in humans. American journal of physiology. Endocrinology and metabolism 20010201
Angiotensin II is involved in nitric oxide synthase and cyclo-oxygenase inhibition-induced leukocyte-endothelial cell interactions in vivo. British journal of pharmacology 20010201
Amino-terminal modification and tyrosine phosphorylation of [corrected] carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain. Neurobiology of disease 20010201
Bone marrow stem cell protection from chemotherapy by low--molecular-weight compounds. Experimental hematology 20010201
Hereditary non-spherocytic haemolytic anaemia due to red blood cell glutathione synthetase deficiency in four unrelated patients from Spain: clinical and molecular studies. British journal of haematology 20010201
Model organisms: new insights into ion channel and transporter function. L-type calcium channels regulate epithelial fluid transport in Drosophila melanogaster. American journal of physiology. Cell physiology 20010201
A simultaneous assay method for L-glutamate and L-pyroglutamate contents in soy sauce using a 5-oxoprolinase (without ATP hydrolyzing activity). Bioscience, biotechnology, and biochemistry 20010201
Inhibition of a model protease--pyroglutamate aminopeptidase by a natural oligosaccharide gum from Hakea gibbosa. International journal of pharmaceutics 20010116
The role of calcium in the activation of glycogen phosphorylase in the fat body of the fruit beetle, Pachnoda sinuata, by hypertrehalosaemic hormone. Biochimica et biophysica acta 20010115
Imide and lactam derivatives of N-benzylpyroglutamyl-L-phenylalanine as VCAM/VLA-4 antagonists. Bioorganic & medicinal chemistry letters 20010108
Vagal-enteric interface: vagal activation-induced expression of c-Fos and p-CREB in neurons of the upper gastrointestinal tract and pancreas. The Anatomical record 20010101
Promoting glutathione synthesis after spinal cord trauma decreases secondary damage and promotes retention of function. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101
Effects of the calcium release inhibitor dantrolene and the Ca2+-ATPase inhibitor thapsigargin on spinal nociception in rats. Pharmacology 20010101
Fertilization promoting peptide--a possible regulator of sperm function in vivo. Vitamins and hormones 20010101
Effect of the hemoregulatory peptide (pEEDCK)2 (pyroGlu-Glu-Asp-Cys-Lys)2 and MIP-1alpha is reduced in bone marrow cultures from patients with chronic myeloid leukemia (CML). Stem cells (Dayton, Ohio) 20010101
[Metadoxyl in combined treatment of alcohol damage to the liver]. Klinicheskaia meditsina 20010101
Fast analysis of water samples for detection of anions by capillary zone electrophoresis. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20010101
Survivability of biomolecules during extraterrestrial delivery: new results on pyrolysis of amino acids and poly-amino acids. Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20010101
Limited heat-shock protein 72 induction in Caco-2 cells by L-glutamine. Digestion 20010101
Effect of tumour size on the in vivo growth inhibition of human colon carcinoma cells (HT-29) by colon mitosis inhibitor. In vivo (Athens, Greece) 20010101
Control of gonadotropin secretion by follicle-stimulating hormone-releasing factor, luteinizing hormone-releasing hormone, and leptin. Archives of medical research 20010101
Stability and CTL-activity of P40/ELA melanoma vaccine candidate. Biologicals : journal of the International Association of Biological Standardization 20010101
A novel cis-peptide bond motif inducing beta-turn type VI. The synthesis of enkephalin analogues modified with 4-aminopyroglutamic acid. Acta biochimica Polonica 20010101
A third active AKH is present in the pyrgomorphid grasshoppers Phymateus morbillosus and Dictyophorus spumans. Insect biochemistry and molecular biology 20001101
Synthesis and characterization of water-soluble silver(I) complexes with L-histidine (H2his) and (S)-(-)-2-pyrrolidone-5-carboxylic acid (H2pyrrld) showing a wide spectrum of effective antibacterial and antifungal activities. Crystal structures of chiral helical polymers [Ag(Hhis)]n and ([Ag(Hpyrrld)]2)n in the solid state. Inorganic chemistry 20000724
A new member of the AKH/RPCH family that stimulates locomotory activity in the firebug, Pyrrhocoris apterus (Heteroptera). Insect biochemistry and molecular biology 20000601
Effects of L-2-oxothiazolidine-4-carboxylate on the cytotoxic activity and toxicity of cyclophosphamide in mice bearing B16F10 melanoma liver metastases. Melanoma research 20000401
Synthesis and in vitro anti-HIV activity in human monocyte-derived macrophages of 2-oxothiazolidine-4(R)-carboxylic acid derivatives. Journal of medicinal chemistry 19991118
The hemoregulatory peptide pEEDCK may inhibit stem cell proliferation via hydropathic binding to antisense sequence motifs in interleukin-11 and other growth factors. Molecular pharmacology 19991001
Tissue-specific regulation of glutathione homeostasis and the activator protein-1 (AP-1) response in the rat conceptus. Biochemical pharmacology 19990515
The growth-inhibiting epidermal pentapeptide, pyroGlu-glu-asp-ser-GlyOH, inhibits growth and alters gene expression in non-transformed NC3H10 and transformed TC3H10 fibroblasts. Oncology reports 19990101
Activated granulocytes oxidize the endogenous stem cell inhibitory peptide pGlu-Glu-Asp-Cys-Lys (pEEDCK) to the stimulatory dimer: a redox-mediated mechanism for demand-induced hematopoietic regulation. Experimental hematology 19980801
Analogs of Manduca adipokinetic hormone tested in a bioassay and in a receptor-binding assay. Peptides 19980101
Isolation and characterization of Melanoplus sanguinipes adipokinetic hormone: a new member of the AKH/RPCH family. Biochemical and biophysical research communications 19971029
Protective effects of L-2-oxothiazolidine-4-carboxylate treatment on cyclophosphamide-induced cystitis in rats. The Journal of urology 19970501
L-2-oxothiazolidine-4-carboxylic acid inhibits human immunodeficiency virus type 1 replication in mononuclear phagocytes and lymphocytes. Clinical and diagnostic laboratory immunology 19970501
No. 302, a newly synthesized [pGlu4,Cyt6]AVP(4-9) analogue, prevents the disruption of avoidance behavior. Behavioural brain research 19970201
Reduction in the duration of myelotoxicity associated with radioimmunotherapy with infusions of the hemoregulatory peptide, HP5b in mice. International journal of cancer 19970127
Distinct sequences of AKH/RPCH family members in beetle (Scarabaeus-species) corpus cardiacum contain three aromatic amino acid residues. Biochemical and biophysical research communications 19970103
Hyperprolinaemia caused by novel members of the adipokinetic hormone/red pigment-concentrating hormone family of peptides isolated from corpora cardiaca of onitine beetles. The Biochemical journal 19970101
Insect neuropeptide leucopyrokinin analogues--synthesis and antinociceptive effect in rats. Polish journal of pharmacology 19970101
Septide and neurokinin A are high-affinity ligands on the NK-1 receptor: evidence from homologous versus heterologous binding analysis. FEBS letters 19961216
Hydrolytic cleavage of pyroglutamyl-peptide bond. III. A highly selective cleavage in 70% methanesulfonic acid. Chemical & pharmaceutical bulletin 19961101
Probing the V1a vasopressin receptor binding site with pyroglutamate-substituted linear antagonists. Neuropeptides 19960201
Supplementation with L-2-oxothiazolidine-4-carboxylic acid, a cysteine precursor, does not protect against lipid peroxidation in puromycin aminonucleoside-induced nephropathy. Experimental nephrology 19960101
Amino acid sequence of CAP2b, an insect cardioacceleratory peptide from the tobacco hawkmoth Manduca sexta. FEBS letters 19950911
Primary structure of a novel neuropeptide isolated from the corpora cardiaca of periodical cicadas having adipokinetic and hypertrehalosemic activities. Insect biochemistry and molecular biology 19950901
[A granulopoiesis inhibitor. Synthesis and biological activity]. Bioorganicheskaia khimiia 19950601
Inhibitory peptides in hematopoiesis. Experimental hematology 19950601
L-2-oxothiazolidine-4-carboxylic acid (procysteine) inhibits expression of the human immunodeficiency virus and expression of the interleukin-2 receptor alpha chain. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 19950201
Isolation and primary structures of neuropeptides of the AKH/RPCH family from various termite species. Peptides 19950101
Isolation of two AKH-related peptides from cicadas. Archives of insect biochemistry and physiology 19950101
Zinc and the mitosis-inhibitory epidermal pentapeptide (EPP) form a stimulatory chelated dimer. Archives of dermatological research 19950101
Biologically active pyroglutamyl N-terminal oligopeptides: parts of larger molecules? Physiological chemistry and physics and medical NMR 19950101
Regional distribution and immunocytological localization of red pigment concentrating hormone in the crayfish eyestalk. General and comparative endocrinology 19940901
A novel adipokinetic octapeptide found in the damselflies Pseudagrion inconspicuum and Ischnura senegalensis. The Biochemical journal 19940901
Glutathione precursor and antioxidant activities of N-acetylcysteine and oxothiazolidine carboxylate compared in in vitro studies of HIV replication. AIDS research and human retroviruses 19940801
Metamorphosin A: a novel peptide controlling development of the lower metazoan Hydractinia echinata (Coelenterata, Hydrozoa). Developmental biology 19940601
Role of oxygen free radicals in cocaine-induced vascular disruption in mice. Teratology 19940301
A novel peptide in the AKH/RPCH family isolated from the corpora cardiaca of the Emperor dragonfly, Anax imperator. Peptides 19940101
Beta-receptor blockade by propranolol modifies the effect of the inhibitory, endogenous epidermal pentapeptide on epidermal cell flux at the G2-M transition but not at the G1-S transition. Epithelial cell biology 19940101
Moderate enhancement of the promotion phase of skin tumorigenesis in hairless mice by topical pretreatment with a mitosis-inhibiting epidermal pentapeptide. Carcinogenesis 19931201
The neuropeptide Phe-Met-Arg-Phe-NH2 (FMRFamide) increases levels of inositol 1,4,5-trisphosphate in the tentacle retractor muscle of Helix aspersa. Experimental physiology 19931101
Isolation, identification and synthesis of locustapyrokinin II from Locusta migratoria, another member of the FXPRL-amide peptide family. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 19930901
Pre-CFU-S quiescence and stem cell exhaustion after cytostatic drug treatment: protective effects of the inhibitory peptide pGlu-Glu-Asp-Cys-Lys (pEEDCK). Blood 19930401
Audiogenic seizures in magnesium-deficient mice: effects of magnesium pyrrolidone-2-carboxylate, magnesium acetyltaurinate, magnesium chloride and vitamin B-6. Magnesium research 19930301
Isolation of Antho-RFamide related peptides from the eyestalks of blue crab. Comparative biochemistry and physiology. B, Comparative biochemistry 19930201
Primary structure of a cardioactive neuropeptide from the tobacco hawkmoth, Manduca sexta. FEBS letters 19921123
Hydra head activator peptide has trophic activity for eukaryotic neurons. Brain research. Developmental brain research 19920724
Isolation of the neuropeptide less than Glu-Trp-Leu-Lys-Gly-Arg-Phe-NH2 (Pol-RFamide II) from the hydromedusa Polyorchis penicillatus. Biochemical and biophysical research communications 19920316
Isolation and primary structure of a novel pheromonotropic neuropeptide structurally related to leucopyrokinin from the armyworm larvae, Pseudaletia separata. Biochemical and biophysical research communications 19920131
Modulation of KB and A431 cell adhesion by epidermal growth inhibitory pentapeptide. Virchows Archiv. B, Cell pathology including molecular pathology 19920101
Effect of combination treatment with analogs of luteinizing hormone-releasing hormone (LH-RH) or somatostatin and 5-fluorouracil on pancreatic cancer in hamsters. International journal of cancer 19910909
A unique charged tyrosine-containing member of the adipokinetic hormone/red-pigment-concentrating hormone peptide family isolated and sequenced from two beetle species. The Biochemical journal 19910501
Primary structure of the precursor for the sea anemone neuropeptide Antho-RFamide (less than Glu-Gly-Arg-Phe-NH2). Proceedings of the National Academy of Sciences of the United States of America 19910315
Protection from arabinofuranosylcytosine and n-mustard-induced myelotoxicity using hemoregulatory peptide pGlu-Glu-Asp-Cys-Lys monomer and dimer. Blood 19910315
The adipokinetic neuropeptide of Mantodea. Sequence elucidation and evolutionary relationships. Biological chemistry Hoppe-Seyler 19910301
The peptide pyroGlu-Gln-Gly-Ser-Asn, isolated from mouse liver, inhibits growth of rat hepatoma cells in vitro. Carcinogenesis 19910201
Isolation and structure elucidation of a novel adipokinetic hormone (Lom-AKH-III) from the glandular lobes of the corpus cardiacum of the migratory locust, Locusta migratoria. European journal of biochemistry 19910130
Inhibitory epidermal pentapeptide modulates proliferation and differentiation of transformed mouse epidermal cells in vitro. Virchows Archiv. B, Cell pathology including molecular pathology 19910101
The epidermal pentapeptide pyroGlu-Glu-Asp-Ser-GlyOH inhibits murine hair growth in vivo and in vitro. Dermatologica 19910101
Degradation of adipokinetic hormone family peptides by a circulating endopeptidase in the insect Manduca sexta. Peptides 19910101
An efficient chemical-enzymatic synthesis of LHRH N-terminal pentapeptide. Biomedica biochimica acta 19910101
Inhibition of hematopoietic stem cell proliferation by hemoregulatory peptide pyroGlu-Glu-Asp-Cys-Lys (pEEDCK) provides protection against short-term neutropenia and long-term damage. Annals of the New York Academy of Sciences 19910101
The use of haemoregulatory peptides (pEEDCK monomer and dimer) for reduction of cytostatic drug induced haemopoietic damage. Cancer treatment reviews 19900901
The fruitfly Drosophila melanogaster contains a novel charged adipokinetic-hormone-family peptide. The Biochemical journal 19900715
Isolation and structure of a novel charged member of the red-pigment-concentrating hormone-adipokinetic hormone family of peptides isolated from the corpora cardiaca of the blowfly Phormia terraenovae (Diptera). The Biochemical journal 19900715
The putative ancestral peptide of the adipokinetic/red-pigment-concentrating hormone family isolated and sequenced from a dragonfly. Biological chemistry Hoppe-Seyler 19900601
TRH-extended peptides in the olfactory lobe are formed by incomplete cleavage at pairs of arginine residues in the TRH prohormone. FEBS letters 19900521
Norvaline2-TRH: binding to TRH receptors in rat brain homogenates. European journal of pharmacology 19900503
Prevention of hematotoxic side effects of cytostatic drugs in mice by a synthetic hemoregulatory peptide. Cancer research 19900115
Mouse epidermal cell renewal after topical treatment with different concentrations of the epidermal peptide pyroGlu-Glu-Asp-Ser-GlyOH. Virchows Archiv. B, Cell pathology including molecular pathology 19900101
UVB-induced epidermal hyperproliferation is modified by a single, topical treatment with a mitosis inhibitory epidermal pentapeptide. The Journal of investigative dermatology 19900101
The primary structure of the hypertrehalosemic neuropeptide from tenebrionid beetles: a novel member of the AKH/RPCH family. Peptides 19900101
Pentapeptide inhibitor of epidermal mitosis: production and responsiveness in cultures of normal, transformed and neoplastic human keratinocytes. Carcinogenesis 19891201
Suppressive biological activity of a synthetic pentapeptide on highly enriched human and murine marrow hematopoietic progenitors: synergism with recombinant human tumor necrosis factor-alpha and interferon-gamma. Experimental hematology 19891001
Biosynthesis of adipokinetic hormones (AKHs): further characterization of precursors and identification of novel products of processing. The Journal of neuroscience : the official journal of the Society for Neuroscience 19890301
Enhancement of methylnitrosourea-induced skin tumorigenesis and carcinogenesis in hairless mice by pretreatment with a mitosis-inhibiting epidermal pentapeptide. Carcinogenesis 19890201
Controversies in TRH biosynthesis and strategies towards the identification of a TRH precursor. Annals of the New York Academy of Sciences 19890101
The metabolic neuropeptides of the corpus cardiacum from the potato beetle and the American cockroach are identical. Peptides 19890101
Isolation of less than Glu-Ser-Leu-Arg-Trp-NH2, a novel neuropeptide from sea anemones. Brain research 19880301
[A synthetic peptide from Helix aspersa raises arterial pressure in rats]. Zhurnal evoliutsionnoi biokhimii i fiziologii 19880101
Primary sequence analysis by fast atom bombardment mass spectrometry of a peptide with adipokinetic activity from the corpora cardiaca of the cricket Gryllus bimaculatus. Biochemical and biophysical research communications 19871231
Effect of pyroglutamic acid stereoisomers on ECS and scopolamine-induced memory disruption and brain acetylcholine levels in the rat. Pharmacological research communications 19871201
Inhibitory activity of a synthetic pentapeptide on leukaemic myelopoiesis both in vitro and in vivo in rats. European journal of haematology 19871101
The actions of FMRFamide-like peptides on visceral and somatic muscles of the snail Helix aspersa. The Journal of experimental biology 19870901
Sequential processing reactions in the formation of hormone amides. European journal of biochemistry 19870817
Isolation and structure of an epidermal mitosis inhibiting pentapeptide. Biochemical and biophysical research communications 19870814
Specific processing of the thyrotropin-releasing prohormone in rat brain and spinal cord. European journal of biochemistry 19870615
Identification of a mammalian glutaminyl cyclase converting glutaminyl into pyroglutamyl peptides. Proceedings of the National Academy of Sciences of the United States of America 19870601
Active fragments and analogs of the insect neuropeptide leucopyrokinin: structure-function studies. Biochemical and biophysical research communications 19860630
Processing of the thyrotropin releasing hormone (TRH) precursor in Xenopus skin and bovine hypothalamus: evidence for the existence of extended forms of TRH. Regulatory peptides 19860501
Primary structure of gonadotropin-releasing hormone from lamprey brain. The Journal of biological chemistry 19860415
Isolation and primary structure of a peptide from the corpora cardiaca of Heliothis zea with adipokinetic activity. Biochemical and biophysical research communications 19860313
Immunohistochemical localization in the rat brain of the precursor for thyrotropin-releasing hormone. Science (New York, N.Y.) 19850913
[Synthesis of cyclic and non-cyclic tachykinin partial sequences. 2. Synthesis of the homocyclic substance P(6-11) hexapeptide]. Die Pharmazie 19850801
Rohdei-litorin: a new peptide from the skin of Phyllomedusa rohdei. FEBS letters 19850311
Arterial blood pressure response in conscious rabbits to administration of C-terminal fragment of substance P into the cerebral ventricles, intravenously and intragastrically. Arzneimittel-Forschung 19850101
The isolation and characterization of an insulin-releasing tetrapeptide from urines of patients with lipoatrophic diabetes. Biochemical and biophysical research communications 19840718
C-terminal amidation of neuropeptides. Gly-Lys-Arg extension an efficient precursor of C-terminal amide. FEBS letters 19840213
Cleavage of Trimeresurus flavoviridis phospholipase A2 with cyanogen bromide: sequence of the short peptide fragment and formation of a noncovalently bonded complex from the fragments. Journal of biochemistry 19810801
An approach to the elucidation of metabolic breakdown products of the luteinizing hormone-releasing hormone. Journal of medicinal chemistry 19810601
Preparation of 3H-[3-M3-His2]TRH as an improved ligand for TRH receptors. Neuroendocrinology 19810501
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