Home Carboxys 3-Benzofurancarboxylic acid,4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-,3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2R,3R)-

3-Benzofurancarboxylic acid,4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-,3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2R,3R)-

CAS No.:
115939-25-8
Catalog Number:
AG00IKKY
Molecular Formula:
Molecular Weight:
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Purity
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Product Description
Catalog Number:
AG00IKKY
Chemical Name:
3-Benzofurancarboxylic acid,4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-,3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2R,3R)-
CAS Number:
115939-25-8
MDL Number:
MFCD07779133
IUPAC Name:
(2R)-2-[(E)-3-[(2R,3R)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyl]oxy-3-(3,4-dihydroxyphenyl)propanoic acid
InChI:
InChI=1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28-,31-,32+/m1/s1
InChI Key:
SNKFFCBZYFGCQN-PDVBOLEISA-N
Properties
Complexity:
1290  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
1  
Exact Mass:
718.153g/mol
Formal Charge:
0
Heavy Atom Count:
52  
Hydrogen Bond Acceptor Count:
16  
Hydrogen Bond Donor Count:
9  
Isotope Atom Count:
0
Molecular Weight:
718.62g/mol
Monoisotopic Mass:
718.153g/mol
Rotatable Bond Count:
14  
Topological Polar Surface Area:
278A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4  
Literature
Title Journal
Salvianolic acid B attenuates doxorubicin-induced ER stress by inhibiting TRPC3 and TRPC6 mediated Ca(2+) overload in rat cardiomyocytes. Toxicology letters 20170705
Salvianolic acid B protects against chronic alcoholic liver injury via SIRT1-mediated inhibition of CRP and ChREBP in rats. Toxicology letters 20170205
Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats. Toxicology letters 20140715
Salvianolic acid B attenuates toxin-induced neuronal damage via Nrf2-dependent glial cells-mediated protective activity in Parkinson's disease models. PloS one 20140101
Cardioprotective effect of salvianolic acid B against arsenic trioxide-induced injury in cardiac H9c2 cells via the PI3K/Akt signal pathway. Toxicology letters 20130204
Biotransformation of salvianolic acid B by Fusarium oxysporum f. sp. Cucumerinum and its two degradation routes. Natural product communications 20120701
The use of PEGylated liposomes to prolong the circulation lifetime of salvianolic acid B. Fitoterapia 20120601
Protective effects of Salvianolic acid B on Schwann cells apoptosis induced by high glucose. Neurochemical research 20120501
[Study on preparation method of Yueanjian for treatmen of premenstrual syndrome]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401
Production of salvianolic acid B in roots of Salvia miltiorrhiza (Danshen) during the post-harvest drying process. Molecules (Basel, Switzerland) 20120227
Metabolic transformation of DMBA-induced carcinogenesis and inhibitory effect of salvianolic acid b and breviscapine treatment. Journal of proteome research 20120203
[Protective effect of salvianolic acid B on isolated heart ischemia/reperfusion injury in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120201
Inhibitory effects of salvianolic acid B on apoptosis of Schwann cells and its mechanism induced by intermittent high glucose. Life sciences 20120116
Tanshinone I increases CYP1A2 protein expression and enzyme activity in primary rat hepatocytes. Phytomedicine : international journal of phytotherapy and phytopharmacology 20120115
Salvianolic acid B prevents bone loss in prednisone-treated rats through stimulation of osteogenesis and bone marrow angiogenesis. PloS one 20120101
Direct stimulation of adult neural stem/progenitor cells in vitro and neurogenesis in vivo by salvianolic acid B. PloS one 20120101
Enhancing effects of different dosages of borneol on pharmacokinetics of salvanic acid B after oral administration to rats. Journal of Asian natural products research 20120101
Cognitive dysfunctions induced by a cholinergic blockade and Aβ 25-35 peptide are attenuated by salvianolic acid B. Neuropharmacology 20111201
Salvianolic acid B and its liposomal formulations: anti-hyperalgesic activity in the treatment of neuropathic pain. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120
Determination and biosynthesis of multiple salvianolic acids in hairy roots of Salvia miltiorrhiza. Yao xue xue bao = Acta pharmaceutica Sinica 20111101
[Effect of salvianolic acid B and tetrahydropalmatine on the L-type calcium channel of rat ventricular myocytes]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20111101
Improving the NQO1-inducing activities of phenolic acids from radix Salvia miltiorrhiza: a methylation strategy. Chemical biology & drug design 20111001
Salvianolic acid B modulates the expression of drug-metabolizing enzymes in HepG2 cells. Hepatobiliary & pancreatic diseases international : HBPD INT 20111001
Salvianolic acid B inhibits the TLR4-NFκB-TNFα pathway and attenuates neonatal rat cardiomyocyte injury induced by lipopolysaccharide. Chinese journal of integrative medicine 20111001
[Study on the quality standard of danmo capsule]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20111001
Comparative pharmacokinetic and bioavailability studies of three salvianolic acids after the administration of Salviae miltiorrhizae alone or with synthetical borneol in rats. Fitoterapia 20110901
Pharmacokinetics of phenolic compounds of Danshen extract in rat blood and brain by microdialysis sampling. Journal of ethnopharmacology 20110614
[Capillary electrophoresis with field-enhanced stacking for determination of water-soluble active principles in Salvia miltiorrhiza var. miltiorrhiza f. alba]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601
In Salvia miltiorrhiza, phenolic acids possess protective properties against amyloid β-induced cytotoxicity, and tanshinones act as acetylcholinesterase inhibitors. Environmental toxicology and pharmacology 20110501
Studies on the interaction of salvianolic acid B with human hemoglobin by multi-spectroscopic techniques. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110401
Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways. Therapeutic advances in cardiovascular disease 20110401
Plant density-dependent variations in bioactive markers and root yield in Australian-grown Salvia miltiorrhiza Bunge. Chemistry & biodiversity 20110401
[Effect of salvianolic acid B on CD14 expression in rats with liver fibrosis]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110401
Metabolomic strategy to study therapeutic and synergistic effects of tanshinone IIA, salvianolic acid B and ginsenoside Rb1 in myocardial ischemia rats. Journal of ethnopharmacology 20110308
[Effects of soil water content on seedlings growth and active ingredients of Salvia miltiorrhiza]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110201
Salvianolic acid B inhibits low-density lipoprotein oxidation and neointimal hyperplasia in endothelium-denuded hypercholesterolaemic rabbits. Journal of the science of food and agriculture 20110115
Therapeutic effects of SMND-309, a new metabolite of salvianolic acid B, on experimental liver fibrosis. European journal of pharmacology 20110110
Salvianolic acid B inhibits autophagy and protects starving cardiac myocytes. Acta pharmacologica Sinica 20110101
Differential proteomic analysis of platelets suggested possible signal cascades network in platelets treated with salvianolic acid B. PloS one 20110101
Identification of the major constituents in Xuebijing injection by HPLC-ESI-MS. Phytochemical analysis : PCA 20110101
Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection. Journal of biomedical science 20110101
Modulation of growth and angiogenic potential of oral squamous carcinoma cells in vitro using salvianolic acid B. BMC complementary and alternative medicine 20110101
[The quality of Salvia miltforthiza from Beijing suburbs with different growing modes]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110101
Cardio-protection of salvianolic acid B through inhibition of apoptosis network. PloS one 20110101
Simultaneous determination of six phenolic constituents of Danshen injection in rat plasma by LC-ESI-MS and its application to a pharmacokinetic study. European journal of mass spectrometry (Chichester, England) 20110101
Combination of acupuncture and chinese medicinal herbs in treating model rats with polycystic ovary syndrome. African journal of traditional, complementary, and alternative medicines : AJTCAM 20110101
[Intestinal absorption properties of three components in salvianolic acid extract and the effect of borneol on their absorption in rats]. Yao xue xue bao = Acta pharmaceutica Sinica 20101201
Neuroprotective effects of salvianolic acid B against oxygen-glucose deprivation/reperfusion damage in primary rat cortical neurons. Chinese medical journal 20101201
[Dynamic extraction process of salvianolic acids]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101101
[Fingerprints of Tongmai Keli by HPLC-DAD-MS]. Yao xue xue bao = Acta pharmaceutica Sinica 20101101
Antioxidant activities of leaf extract of Salvia miltiorrhiza Bunge and related phenolic constituents. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101001
[Effects of salvianolic acid B and diammonium glycyrrhizinate on portal pressure in rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20101001
Accumulation of salicylic acid-induced phenolic compounds and raised activities of secondary metabolic and antioxidative enzymes in Salvia miltiorrhiza cell culture. Journal of biotechnology 20100720
The effects of salvianolic acid B from radix salvia miltiorrhizae on the oral pharmacokinetics of metoprolol and metoprolol acid in rats. Phytotherapy research : PTR 20100601
Combination effects of salvianolic acid B with low-dose celecoxib on inhibition of head and neck squamous cell carcinoma growth in vitro and in vivo. Cancer prevention research (Philadelphia, Pa.) 20100601
Pharmacokinetic interactions induced by content variation of major water-soluble components of Danshen preparation in rats. Acta pharmacologica Sinica 20100501
Salvianolic acid B attenuates hepatocyte apoptosis by regulating mediators in death receptor and mitochondrial pathways. Experimental biology and medicine (Maywood, N.J.) 20100501
Cardioprotective effect of SMND-309, a novel derivate of salvianolic acid B on acute myocardial infarction in rats. Basic & clinical pharmacology & toxicology 20100401
Effects of salvianolic acids on oxidative stress and hepatic fibrosis in rats. Toxicology and applied pharmacology 20100115
[Effects of salvianolic acid B on lipid peroxidation and metalloproteinase-2 activity in fibrotic liver in rat]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100101
Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-beta1 signal transduction pathway in vivo and in vitro. BMC cell biology 20100101
Salvianolic acid B protects SH-SY5Y neuroblastoma cells from 1-methyl-4-phenylpyridinium-induced apoptosis. Biological & pharmaceutical bulletin 20100101
Salvianolic acid B functioned as a competitive inhibitor of matrix metalloproteinase-9 and efficiently prevented cardiac remodeling. BMC pharmacology 20100101
The strategy of combined ischemia preconditioning and salvianolic acid-B pretreatment to prevent hepatic ischemia-reperfusion injury in rats. Digestive diseases and sciences 20091201
Salvianolic acid B-vitamin C synergy in cardiac differentiation from embryonic stem cells. Biochemical and biophysical research communications 20091002
Cardioprotection and matrix metalloproteinase-9 regulation of salvianolic acids on myocardial infarction in rats. Planta medica 20091001
Liquid chromatography mass spectrometry for the determination of salvianolic acid B, a natural compound from the herb Danshen in rat plasma and application to pharmacokinetic study. Biomedical chromatography : BMC 20091001
In vitro anti-fibrotic activities of herbal compounds and herbs. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091001
Effect of sodium caprate on the oral absorptions of danshensu and salvianolic acid B. International journal of pharmaceutics 20090908
[Evaluation of different combinations of components of Chinese formulation shuangshentongguan by using AUC values]. Yao xue xue bao = Acta pharmaceutica Sinica 20090901
Protections of SMND-309, a novel derivate of salvianolic acid B, on brain mitochondria contribute to injury amelioration in cerebral ischemia rats. Phytomedicine : international journal of phytotherapy and phytopharmacology 20090801
Microwave-assisted extraction with water for fast extraction and simultaneous RP-HPLC determination of phenolic acids in radix Salviae Miltiorrhizae. Journal of separation science 20090701
HPLC profiles and biomarker contents of Australian-grown Salvia miltiorrhiza f. alba roots. Chemistry & biodiversity 20090701
[Capillary electrophoresis fingerprints of compound Danshen Dropping Pill]. Se pu = Chinese journal of chromatography 20090701
Natural product inhibitors of protein-protein interactions mediated by Src-family SH2 domains. Bioorganic & medicinal chemistry letters 20090615
Salvianolic acid B inhibits growth of head and neck squamous cell carcinoma in vitro and in vivo via cyclooxygenase-2 and apoptotic pathways. International journal of cancer 20090501
Microsphere resin chromatography combined with microbial biotransformation for the separation and purification of salvianolic acid B in aqueous extract of roots of Salvia multiorrihza Bunge. Journal of chromatography. A 20090501
[Removal of the colloidal impurities in the purification of salvianolic acid B]. Se pu = Chinese journal of chromatography 20090501
Seasonal variations in bioactive marker contents in Australian-grown Salvia miltiorrhiza roots. Chemistry & biodiversity 20090401
SMND-309, a novel derivate of salvianolic acid B, attenuates apoptosis and ameliorates mitochondrial energy metabolism in rat cortical neurons. Basic & clinical pharmacology & toxicology 20090201
Effect of Guanxin No.2 decoction on gene expression in different areas of the myocardial infarcted heart of rats using microarray technology. The Journal of pharmacy and pharmacology 20090201
Salvianolic acid B in vitro inhibited matrix metalloproteinases-1, -2, and -9 activities. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20090201
Cultivar variations of Australian-grown Danshen (Salvia miltiorrhiza): bioactive markers and root yields. Chemistry & biodiversity 20090201
Protective effect of salvianolic acid B on chronic pancreatitis induced by trinitrobenzene sulfonic acid solution in rats. Pancreas 20090101
Salvianolic acid B protects human endothelial cells from oxidative stress damage: a possible protective role of glucose-regulated protein 78 induction. Cardiovascular research 20090101
The attenuation effect of 3,4-dihydroxy-phenyl lactic acid and salvianolic acid B on venular thrombosis induced in rat mesentery by photochemical reaction. Clinical hemorheology and microcirculation 20090101
[Experiment of extracting Salviae miltiorrhizae on using O/W microemulsion]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081101
[Effect of different combinations of compound Danshen preparation on pharmacokinetic parameters of salvianolic acid B in rat plasma]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081101
Comparison of cardioprotective effects using salvianolic acid B and benazepril for the treatment of chronic myocardial infarction in rats. Naunyn-Schmiedeberg's archives of pharmacology 20080901
Enhanced oral bioavailability of salvianolic acid B by phospholipid complex loaded nanoparticles. Die Pharmazie 20080901
Decreased FKBP12.6 expression and enhanced endothelin receptor signaling associated with arrhymogenesis in myocardial infarction rats. Phytotherapy research : PTR 20080801
[New method of multi-components quantitation by one marker new method for quality evaluation of Guanmaikang capsula]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080801
Inhibitory effects of salvianolic acid B on the high glucose-induced mesangial proliferation via NF-kappaB-dependent pathway. Biological & pharmaceutical bulletin 20080701
Pharmacokinetics of salvianolic acids after intravenous injection, with and without Panax quinquefolium protopanaxadiol saponins, in rats. Journal of ethnopharmacology 20080522
Salvianolic acids prevent acute doxorubicin cardiotoxicity in mice through suppression of oxidative stress. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080501
[Absorption and isolation of macroporous resin for five salvianolic acids from Salviae mitiorrhizae]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080501
Protective effects of dihydroxylphenyl lactic acid and salvianolic acid B on LPS-induced mesenteric microcirculatory disturbance in rats. Shock (Augusta, Ga.) 20080201
One-step purification of 3,4-dihydroxyphenyllactic acid, salvianolic acid B, and protocatechualdehyde from Salvia miltiorrhiza Bunge by isocratic stepwise hydrogen bond adsorption chromatography on cross-linked 12% agarose. Journal of chromatographic science 20080201
[A new method for quick analysis of tanshinone II(A) and salvianolic acid in Fufang Danshen tablets by AOTF-near infrared spectroscopy]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080201
Mechanisms of the dilator action of cryptotanshinone on rat coronary artery. European journal of pharmacology 20080114
Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080101
Salvianolic acid B, an antioxidant from Salvia miltiorrhiza, prevents 6-hydroxydopamine induced apoptosis in SH-SY5Y cells. The international journal of biochemistry & cell biology 20080101
Salvianolic acid B inhibits Abeta fibril formation and disaggregates preformed fibrils and protects against Abeta-induced cytotoxicty. Neurochemistry international 20080101
Protective effect of tetramethylpyrazine and salvianolic acid B on apoptosis of rat cerebral microvascular endothelial cell under high shear stress. Clinical hemorheology and microcirculation 20080101
Comparison of cardioprotective effects of salvianolic acid B and benazepril on large myocardial infarction in rats. Pharmacological reports : PR 20080101
Large-scale separation of salvianolic acid B from the Chinese medicinal plant Salvia miltiorrhiza by pH-zone-refining countercurrent chromatography. Journal of separation science 20071201
[Analysis on biomasses and contents of active components in roots of Salvia miltiorrhiza from different populations]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201
[Effect of salvianolic acid B on brain energy metabolism and hydrocephalus of cerebral ischemia in mice at different time]. Yao xue xue bao = Acta pharmaceutica Sinica 20071201
Simultaneous determination and pharmacokinetic study of water-soluble and lipid-soluble components of danshen in rat plasma using HPLC-UV method. Biomedical chromatography : BMC 20071101
HPLC method for comparative study on tissue distribution in rat after oral administration of salvianolic acid B and phenolic acids from Salvia miltiorrhiza. Biomedical chromatography : BMC 20071001
[Optimization of preparative separation and purification of water-soluble substance from Salvia miltiorrhiza by macroporous resins]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071001
Chromatographic fingerprinting analysis of Danshen root (Salvia miltiorrhiza Radix et Rhizoma) and its preparations using high performance liquid chromatography with diode array detection and electrospray mass spectrometry (HPLC-DAD-ESI/MS). Journal of separation science 20070901
[Effects of salvianolic acid B on cerebral energy charge and activity of ATPase in mice with cerebral ischemia]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901
[Application of accelerated solvent extraction technique for analysis of active components in traditional Chinese medicinal herbs]. Se pu = Chinese journal of chromatography 20070901
Protection of PC12 cells from hydrogen peroxide-induced cytotoxicity by salvianolic acid B, a new compound isolated from Radix Salviae miltiorrhizae. Phytomedicine : international journal of phytotherapy and phytopharmacology 20070801
Study on the mechanisms of an extract of Salvia miltiorrhiza on the regulation of permeability of endothelial cells exposed to tumour necrosis factor-alpha. The Journal of pharmacy and pharmacology 20070701
The effect of the major components of Salvia Miltiorrhiza Bunge on bone marrow cells. Journal of ethnopharmacology 20070522
[Pharmacokinetic interactions between the main components in the extracts of Salvia miltiorrhiza Bge. in rat]. Yao xue xue bao = Acta pharmaceutica Sinica 20070301
Salvianolic acid B attenuates MMP-2 and MMP-9 expression in vivo in apolipoprotein-E-deficient mouse aorta and in vitro in LPS-treated human aortic smooth muscle cells. Journal of cellular biochemistry 20070201
One-step separation and purification of 3,4-dihydroxyphenyllactic acid, salvianolic acid B and protocatechualdehyde from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography. Journal of chromatography. A 20070126
Salvianolic acid B inhibits hydrogen peroxide-induced endothelial cell apoptosis through regulating PI3K/Akt signaling. PloS one 20070101
Salvianolic acid B, an aqueous component of danshen (Salvia miltiorrhiza), relaxes rat coronary artery by inhibition of calcium channels. European journal of pharmacology 20061228
Bioavailability of salvianolic acid B in conscious and freely moving rats. International journal of pharmaceutics 20061201
Activation of the iberiotoxin-sensitive BKCa channels by salvianolic acid B of the porcine coronary artery smooth muscle cells. European journal of pharmacology 20060928
Comparison of antioxidant activities between salvianolic acid B and Ginkgo biloba extract (EGb 761). Acta pharmacologica Sinica 20060901
Salvianolic acid B improves motor function after cerebral ischemia in rats. Behavioural pharmacology 20060901
[Quantitative analysis on Radix Salviae miltiorrhizae by NIR]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060901
[Comparison of the inhibitory activities of salvianolic acid B and Ginkgo biloba extract EGb 761 on neurotoxicity of beta-amyloid peptide]. Yao xue xue bao = Acta pharmaceutica Sinica 20060801
Salvianolic acid B from Salvia miltiorrhiza inhibits tumor necrosis factor-alpha (TNF-alpha)-induced MMP-2 upregulation in human aortic smooth muscle cells via suppression of NAD(P)H oxidase-derived reactive oxygen species. Journal of molecular and cellular cardiology 20060701
[Determination of salvianolic acid B and paeoniflorin in Shuangdan granules by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060701
Salvianolic acid B attenuates cyclooxygenase-2 expression in vitro in LPS-treated human aortic smooth muscle cells and in vivo in the apolipoprotein-E-deficient mouse aorta. Journal of cellular biochemistry 20060601
[Research on extracting process for compound shenzhutiaozhi capsule]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060601
Purification of salvianolic acid B from the crude extract of Salvia miltiorrhiza with hydrophilic organic/salt-containing aqueous two-phase system by counter-current chromatography. Journal of chromatography. A 20060526
In vitro protective effects of salvianolic acid B on primary hepatocytes and hepatic stellate cells. Journal of ethnopharmacology 20060421
The preventive effect of salvianolic acid B on malignant transformation of DMBA-induced oral premalignant lesion in hamsters. Carcinogenesis 20060401
[Study on quality standard of Yixin Tablet]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060301
[Study on the water-soluble composition release of compound Danshen sustained-release tablet]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060101
Effects of salvianolic acids on erythrocyte deformability in oleic acid induced acute lung injury in rabbits. Clinical hemorheology and microcirculation 20060101
Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. Journal of clinical pharmacology 20051201
Aqueous extract of Salvia miltiorrhiza attenuates increased endothelial permeability induced by tumor necrosis factor-alpha. International immunopharmacology 20051001
Determination and pharmacokinetic analysis of salvianolic acid B in rat blood and bile by microdialysis and liquid chromatography. Journal of chromatography. A 20050923
[The qualitative analysis and quantitative analysis of purification of salvianolic acids by macroreticular resin]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050901
[Effects of salvianolic acid B on expressions of TGF-beta1 and its receptors in liver of rats with dimethylnitrosamine-induced hepatic fibrosis]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20050701
[Advances in study of the pharmacological effects of danshen on hemorheology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050401
HPLC determination and pharmacokinetic studies of salvianolic acid B in rat plasma after oral administration of Radix Salviae Miltiorrhizae extract. Biomedical chromatography : BMC 20050101
Phenylpropanoid derivatives from edible canna, Canna edulis. Phytochemistry 20040701
Inhibition of shear-induced platelet aggregation in rat by tetramethylpyrazine and salvianolic acid B. Clinical hemorheology and microcirculation 20040101
Salvianolic acid B enhances in vitro angiogenesis and improves skin flap survival in Sprague-Dawley rats. The Journal of surgical research 20031201
Effects of salvianolic acids on endothelial cells against damage induced by cholestane-3beta-5alpha-6beta-triol. Chinese medical journal 20030401
Preparative isolation and purification of salvianolic acid B from the Chinese medicinal plant Salvia miltiorrhiza by high-speed counter-current chromatography. Journal of chromatography. A 20020118
New drugs derived from medicinal plants. Therapie 20020101
[Determination of salvianolic acid B in the radix of Salvia miltiorrhiza Bge. by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20011201
Salvianolic acid B inhibits fibril formation and neurotoxicity of amyloid beta-protein in vitro. Acta pharmacologica Sinica 20010401
A salvianolic acid B-rich fraction of Salvia miltiorrhiza induces neointimal cell apoptosis in rabbit angioplasty model. Histology and histopathology 20010101
Salvianolic acid B attenuates VCAM-1 and ICAM-1 expression in TNF-alpha-treated human aortic endothelial cells. Journal of cellular biochemistry 20010101
Properties