b-D-Galactopyranoside,(3b,4a,16b)-16,23,28-trihydroxyoleana-11,13(18)-dien-3-yl6-deoxy-3-O-b-D-glucopyranosyl-
| Title | Journal |
|---|---|
| Saikosaponin-d-mediated downregulation of neurogenesis results in cognitive dysfunction by inhibiting Akt/Foxg-1 pathway in mice. | Toxicology letters 20180301 |
| Saikosaponin b2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry. | Journal of hepatology 20150301 |
| Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling. | Chemico-biological interactions 20141105 |
| Saikosaponin D disrupts platelet-derived growth factor-β receptor/p38 pathway leading to mitochondrial apoptosis in human LO2 hepatocyte cells: a potential mechanism of hepatotoxicity. | Chemico-biological interactions 20131025 |
| Effect of saikosaponin A on maintenance of intravenous morphine self-administration. | Neuroscience letters 20121031 |
| Solubilization of saikosaponin a by ginsenoside Ro biosurfactant in aqueous solution: mesoscopic simulation. | Journal of colloid and interface science 20121015 |
| Analysis of saikosaponins in rat plasma by anionic adducts-based liquid chromatography tandem mass spectrometry method. | Biomedical chromatography : BMC 20120701 |
| Saikosaponin-d inhibits β-conglycinin induced activation of rat basophilic leukemia-2H3 cells. | International immunopharmacology 20120701 |
| Metabolic fingerprinting by 1HNMR for discrimination of the two species used as Radix Bupleuri. | Planta medica 20120601 |
| Study on the noncovalent interactions of saikosaponins and cytochrome c by electrospray ionization mass spectrometry. | Rapid communications in mass spectrometry : RCM 20120415 |
| Chemopreventive effect of saikosaponin-d on diethylinitrosamine-induced hepatocarcinogenesis: involvement of CCAAT/enhancer binding protein β and cyclooxygenase-2. | Molecular medicine reports 20120301 |
| Large-scale production of saikosaponins through root culturing of Bupleurum falcatum L. using modified airlift reactors. | Journal of bioscience and bioengineering 20120101 |
| [Effects of interferon-alpha combined with saikosaponin on serum T lymphocyte subgroups and hepatic cytokines in mice with immune hepatic injury]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120101 |
| Species discrimination of Radix Bupleuri through the simultaneous determination of ten saikosaponins by high performance liquid chromatography with evaporative light scattering detection and electrospray ionization mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111215 |
| Interaction of the main components from the traditional Chinese drug pair Chaihu-Shaoyao based on rat intestinal absorption. | Molecules (Basel, Switzerland) 20111117 |
| [Optimization of the ultrasound assisted extraction of saikosaponins from Bupleurum falcatum using response surface methodology]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20111101 |
| [Effect of Saikosaponins-d on reversing malignant phenotype of HepG2 cells in vitro]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20111001 |
| [Research on mechanism of energy metabolism disorders of rat's hepatoxicity induced by saikosaponins]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110901 |
| An LC-MS method for simultaneous determination of nine ginsenosides in rat plasma and its application in pharmacokinetic study. | Biomedical chromatography : BMC 20110601 |
| Saikosaponins: a potential treatment option for systemic lupus erythematosus. | Irish journal of medical science 20110301 |
| Analysis of saikosaponins in Bupleuri Radix and Caihu-shugan-san using reversed-phase HPLC with pulsed amperometric detection. | Journal of separation science 20110301 |
| Fast and sensitive LC-DAD-ESI/MS method for analysis of saikosaponins c, a, and d from the roots of Bupleurum Falcatum (Sandaochaihu). | Molecules (Basel, Switzerland) 20110211 |
| Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. | Apoptosis : an international journal on programmed cell death 20110201 |
| Glaucasides A-C, three saikosaponins from Atriplex glauca L. var. ifiniensis (Caball) Maire. | Magnetic resonance in chemistry : MRC 20110201 |
| Inactivation of cystein-aspartic acid protease (caspase)-1 by saikosaponin A. | Biological & pharmaceutical bulletin 20110101 |
| Oleanene glycosides of the aerial parts and seeds of Bupleurum falcatum and the aerial parts of Bupleurum rotundifolium, and their evaluation as anti-hepatitis agents. | Chemical & pharmaceutical bulletin 20110101 |
| Transcriptome analysis of Bupleurum chinense focusing on genes involved in the biosynthesis of saikosaponins. | BMC genomics 20110101 |
| Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry. | Chemistry & biodiversity 20101201 |
| ['Dose-toxicity' relationship study on rat's chronic hepatoxicity of refined products of saikosaponin by alcohol elution]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901 |
| [Breeding of new varieties 'zhongchai no. 2' and 'zhongchai no. 3' of Bupleurum chinense]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100801 |
| [Study on dynamic accumulation of index components from Bupleurum chinense in various collecting periods]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100801 |
| Identification and determination of the saikosaponins in Radix bupleuri by accelerated solvent extraction combined with rapid-resolution LC-MS. | Journal of separation science 20100701 |
| [Study on hepatotoxicity on rats caused by crude extracts of total saikosaponins and correlation with oxidative damage mechanism]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100701 |
| Comparison between evaporative light scattering detection and charged aerosol detection for the analysis of saikosaponins. | Journal of chromatography. A 20100625 |
| Application of accelerated solvent extraction to the investigation of saikosaponins from the roots of Bupleurum falcatum. | Journal of separation science 20100601 |
| Optimization of supercritical fluid extraction of saikosaponins from Bupleurum falcatum with orthogonal array design. | Journal of separation science 20100401 |
| Inhibition of human renin activity by saponins. | Biomedical research (Tokyo, Japan) 20100401 |
| [Therapeutic effects and mechanism of saikosaponin-d in mice with bleomycin-induced pulmonary fibrosis]. | Zhonghua yi xue za zhi 20100330 |
| Estrogen-like activities of saikosaponin-d in vitro: a pilot study. | European journal of pharmacology 20100125 |
| Curcumin and saikosaponin a inhibit chemical-induced liver inflammation and fibrosis in rats. | The American journal of Chinese medicine 20100101 |
| Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells. | Journal of experimental & clinical cancer research : CR 20100101 |
| [Differences of saikosaponin contents in Bupleurum chinense from habitats in Dongling Mountain & Wuling Mountain of Beijing]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201 |
| [Study on the optimal extraction process of chaihushugan powder]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20091101 |
| [Advances in mechanisms of saikosaponins in preventing and treating liver disease]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20091101 |
| Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis. | International immunopharmacology 20090701 |
| [Estrogen-like effects of saikosaponin-d in mice]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20090701 |
| Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation. | Journal of cellular biochemistry 20090515 |
| Fast determination of saikosaponins in Bupleurum by rapid resolution liquid chromatography with evaporative light scattering detection. | Journal of pharmaceutical and biomedical analysis 20090501 |
| Evaluation of traditional Chinese herbal medicine: Chaihu (Bupleuri Radix) by both high-performance liquid chromatographic and high-performance thin-layer chromatographic fingerprint and chemometric analysis. | Journal of chromatography. A 20090313 |
| Application of centrifugal partition chromatography coupled with evaporative light scattering detection for the isolation of saikosaponins-a and -c from Bupleurum falcatum roots. | Journal of separation science 20090101 |
| Characterization and identification of saikosaponins in crude extracts from three Bupleurum species using LC-ESI-MS. | Journal of separation science 20081001 |
| [Inhibitory effects of saikosaponin a on rat hippocampal astrocyte activation in vitro]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081001 |
| Localization and dynamic change of saikosaponin in root of Bupleurum chinense. | Journal of integrative plant biology 20080801 |
| Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats. | Journal of medicinal food 20080601 |
| [Experimental study of saikosaponin-D (SSd) on lipid peroxidation of hepatic fibrosis on rat]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080401 |
| Effects of Bupleurum scorzoneraefolium, Bupleurum falcatum, and saponins on nephrotoxic serum nephritis in mice. | Journal of ethnopharmacology 20080328 |
| [Determination of content of saikoside in Bupleurum Chinense from different sources]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080201 |
| Saireito and saikosaponin D prevent urinary protein excretion via glucocorticoid receptor in adrenalectomized WKY rats with heterologous-phase anti-GBM nephritis. | Nephron. Physiology 20080101 |
| [Effect of saikosaponin alpha on experimental epilepsy in rats]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070601 |
| [Separation and refine of Xiaoyao Pill by macroporous adsorption resin]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070601 |
| A high-performance liquid chromatographic method for saikosaponin a quantification in rat plasma. | Biomedical chromatography : BMC 20070501 |
| [Aike mixture has good anti-inflammatory and analgesic effects on mice]. | Zhonghua nan ke xue = National journal of andrology 20070501 |
| [Effect of saikosaponin-d on rat's glomerular mesangial cell proliferation and extracellular matrix hyperplasia in vitro]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070401 |
| Mechanism of saikosaponin-d in the regulation of rat mesangial cell proliferation and synthesis of extracellular matrix proteins. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20070401 |
| Saikosaponin-d attenuates the development of liver fibrosis by preventing hepatocyte injury. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20070401 |
| Quality control of Chinese medicinal preparations LC/ESI(+)/MS/MS analyses of saikosaponins-a and -c as markers of Bupleuri radix samples. | Journal of pharmaceutical and biomedical analysis 20070219 |
| Inhibitory effects of saikosaponin-d on CCl4-induced hepatic fibrogenesis in rats. | World journal of gastroenterology 20070128 |
| Sho-saiko-to (Xiao-Chai-Hu-Tang) and crude saikosaponins inhibit hepatitis B virus in a stable HBV-producing cell line. | The American journal of Chinese medicine 20070101 |
| Upregulation of isoprenoid pathway genes during enhanced saikosaponin biosynthesis in the hairy roots of Bupleurum falcatum. | Molecules and cells 20061231 |
| Role of four major components in the effect of Si-Ni-San, a traditional Chinese prescription, against contact sensitivity in mice. | The Journal of pharmacy and pharmacology 20060901 |
| [Effect of saikosaponins-d on cyclooxygenase-2 expression of human hepatocellular carcinoma cell line SMMC-7721]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060901 |
| Visual detection of saikosaponins by on-membrane immunoassay and estimation of traditional Chinese medicines containing Bupleuri radix. | Biochemical and biophysical research communications 20060804 |
| [Saikosaponins inhibit increased glutamate and GABA expressions in the hippocampus of pentetrazole-induced slow kindling rats]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060801 |
| Antiviral effects of saikosaponins on human coronavirus 229E in vitro. | Clinical and experimental pharmacology & physiology 20060701 |
| [Effect of saikosaponins on glial fibrillary acidic protein expression in hippocampal astrocytes of pentetrazole-induced chronic kindling rats]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060401 |
| Effects of Saireito, a Japanese herbal medicine, on edema via antagonistic actions against aldosterone in anti-GBM nephritic rats. | Clinical and experimental nephrology 20060301 |
| A novel analytical ELISA-based methodology for pharmacologically active saikosaponins. | Fitoterapia 20060201 |
| [Effect of saikosaponins on epileptic seizure and EEG in pentetrazole-induced chronic kindling rats]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060201 |
| [Studies on fingerprints of Bupleurum chinense from Hebei Province with HPLC-UV]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060201 |
| [Progress in research on antitumor activity of saikosaponin and its mechanism]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060101 |
| Saikosaponin-d inhibits T cell activation through the modulation of PKCtheta, JNK, and NF-kappaB transcription factor. | Biochemical and biophysical research communications 20051230 |
| High performance liquid chromatographic assay of saikosaponins from radix Bupleuri in China. | Biological & pharmaceutical bulletin 20050901 |
| Cholesteryl hemisuccinate as a membrane stabilizer in dipalmitoylphosphatidylcholine liposomes containing saikosaponin-d. | International journal of pharmaceutics 20050826 |
| Determination of saikosaponins a, c, and d in Bupleurum Chinese DC from different areas by capillary zone electrophoresis. | Analytical and bioanalytical chemistry 20050801 |
| [Cholesteryl hemisuccinate as liposomal membrane stabilizer and its use in the preparation of saikosaponin-D liposomes]. | Yao xue xue bao = Acta pharmaceutica Sinica 20050701 |
| Therapeutic mechanism of Saikosaponin-d in anti-Thy1 mAb 1-22-3-induced rat model of glomerulonephritis. | Nephron. Experimental nephrology 20050101 |
| Saikosaponin C induces endothelial cells growth, migration and capillary tube formation. | Life sciences 20041231 |
| [Effect of saikosaponins on epileptic rat electroenciphalogram]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20041201 |
| Involvement of p53, nuclear factor kappaB and Fas/Fas ligand in induction of apoptosis and cell cycle arrest by saikosaponin d in human hepatoma cell lines. | Cancer letters 20040930 |
| The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A549 cells. | Life sciences 20040723 |
| Determination of saikosaponin derivatives in Radix bupleuri and in pharmaceuticals of the chinese multiherb remedy xiaochaihu-tang using liquid chromatographic tandem mass spectrometry. | Analytical chemistry 20040715 |
| Development of an assay system for saikosaponin a using anti-saikosaponin a monoclonal antibodies. | Biological & pharmaceutical bulletin 20040101 |
| [Effect of chailing decoction and its active ingredients on experimental nephritis in rats]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20031001 |
| Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species. | Planta medica 20030801 |
| Antiproliferative constituents from Umbelliferae plants VI. New ursane-type saikosaponin analogs from the fruits of Bupleurum rotundifolium. | Chemical & pharmaceutical bulletin 20030401 |
| ERK signaling pathway is involved in p15INK4b/p16INK4a expression and HepG2 growth inhibition triggered by TPA and Saikosaponin a. | Oncogene 20030220 |
| Saikosaponin-A induces apoptotic mechanism in human breast MDA-MB-231 and MCF-7 cancer cells. | The American journal of Chinese medicine 20030101 |
| Characteristics and mechanism of enzyme secretion and increase in [Ca2+]i in Saikosaponin(I) stimulated rat pancreatic acinar cells. | World journal of gastroenterology 20020615 |
| Effect of saikosaponin-A, a triterpenoid glycoside, isolated from Bupleurum falcatum on experimental allergic asthma. | Phytotherapy research : PTR 20020601 |
| Induction of differentiation in rat C6 glioma cells with Saikosaponins. | Phytotherapy research : PTR 20020301 |
| Antiviral activity of seven iridoids, three saikosaponins and one phenylpropanoid glycoside extracted from Bupleurum rigidum and Scrophularia scorodonia. | Planta medica 20020201 |
| Efficient production of saikosaponins in Bupleurum falcatum root fragments combined with signal transducers. | Applied microbiology and biotechnology 20011101 |
| Involvement of p-15(INK4b) and p-16(INK4a) gene expression in saikosaponin a and TPA-induced growth inhibition of HepG2 cells. | Biochemical and biophysical research communications 20010713 |
| Purification of saponin compounds in Bupleurum falcatum by solvent partitioning and preparative LC. | Bioscience, biotechnology, and biochemistry 20010701 |
| Inhibitory role of GDP on saikosaponin (I) stimulated enzymes secretion and rising of [Ca2+]i in rat pancreatic acini. | Acta pharmacologica Sinica 20010701 |
| Saikosaponin v-1 from roots of Bupleurum chinense DC. | Journal of Asian natural products research 20010101 |
| Effects of saikosaponin-d on aminonucleoside nephrosis in rats. | European journal of pharmacology 19860121 |