Benzoic acid,5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy-, triammonium salt
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The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells. | The Journal of biological chemistry 20150116 |
Aurintricarboxylic acid modulates the affinity of hepatitis C virus NS3 helicase for both nucleic acid and ATP. | Biochemistry 20130910 |
Selective inhibition of the membrane attack complex of complement by low molecular weight components of the aurin tricarboxylic acid synthetic complex. | Neurobiology of aging 20121001 |
Trimethylaurintricarboxylic acid inhibits human DNA methyltransferase 1: insights from enzymatic and molecular modeling studies. | Journal of molecular modeling 20120401 |
Anomalous inhibition of c-Met by the kinesin inhibitor aurintricarboxylic acid. | International journal of cancer 20120301 |
Quantization of bovine serum albumin by fluorescence enhancement effects and corresponding binding of macrocyclic host-protein assembly. | Journal of photochemistry and photobiology. B, Biology 20120105 |
Molecular modeling of inhibitors of human DNA methyltransferase with a crystal structure: discovery of a novel DNMT1 inhibitor. | Advances in protein chemistry and structural biology 20120101 |
Mechanisms of xenogeneic baboon platelet aggregation and phagocytosis by porcine liver sinusoidal endothelial cells. | PloS one 20120101 |
Aurintricarboxylic acid promotes the conversion of naive CD4+CD25- T cells into Foxp3-expressing regulatory T cells. | International immunology 20110901 |
Aurintricarboxylic acid inhibits the nuclear factor-κB-dependent expression of intercellular cell adhesion molecule-1 and endothelial cell selectin on activated human endothelial cells. | Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20110301 |
Investigations on the interactions of aurintricarboxylic acid with bovine serum albumin: Steady state/time resolved spectroscopic and docking studies. | Journal of photochemistry and photobiology. B, Biology 20110110 |
Cosalane and its analogues: a unique class of anti-HIV agents. | Mini reviews in medicinal chemistry 20100901 |
Lack of efficacy of aurintricarboxylic acid and ethacrynic acid against vaccinia virus respiratory infections in mice. | Antiviral chemistry & chemotherapy 20100414 |
Inhibition of enterovirus 71 replication and the viral 3D polymerase by aurintricarboxylic acid. | The Journal of antimicrobial chemotherapy 20100401 |
N-acetylcysteine impairs survival of luteal cells through mitochondrial dysfunction. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20100401 |
Interaction of aurintricarboxylic acid (ATA) with four nucleic acid binding proteins DNase I, RNase A, reverse transcriptase and Taq polymerase. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20091201 |
Characterization of aurintricarboxylic acid as a potent hepatitis C virus replicase inhibitor. | Antiviral chemistry & chemotherapy 20090925 |
Single-strand DNA translation initiation step analyzed by Isothermal Titration Calorimetry. | Biochemical and biophysical research communications 20090731 |
Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening. | Proceedings of the National Academy of Sciences of the United States of America 20090324 |
Aurintricarboxylic acid inhibits influenza virus neuraminidase. | Antiviral research 20090201 |
Citrate-mediated release of aurintricarboxylic acid from a calcium alginate complex: implications for intravaginal HIV chemoprophylaxis and related applications. | Pharmaceutical development and technology 20090101 |
Aurintricarboxylic acid is a potent inhibitor of influenza A and B virus neuraminidases. | PloS one 20090101 |
In vitro and in vivo activity of aurintricarboxylic acid preparations against Cryptosporidium parvum. | The Journal of antimicrobial chemotherapy 20081101 |
Selection of an effective red-pigment producing Monascus pilosus by efficient transformation with aurintricarboxylic acid. | Bioscience, biotechnology, and biochemistry 20081101 |
Posttreatment with the Ca(2+)-Mg(2+)-dependent endonuclease inhibitor aurintricarboxylic acid abolishes genotoxic agent-induced nuclear condensation and DNA fragmentation and decreases death of astrocytes. | Journal of neuroscience research 20081001 |
A new binding assay of von Willebrand factor and glycoprotein Ib using solid-phase biotinylated platelets. | Journal of pharmacological sciences 20081001 |
Apoptosis of mesenchymal cells during the pseudoglandular stage of lung development affects branching morphogenesis. | Experimental lung research 20081001 |
Aurintricarboxylic acid upregulates the thrombomodulin expression of endothelial cells and peripheral blood monocytes. | Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20080901 |
Platelet GPIb complex as a target for anti-thrombotic drug development. | Thrombosis and haemostasis 20080301 |
Gene expression-based screening for inhibitors of PDGFR signaling. | Genome biology 20080101 |
Aurintricarboxylic acid inhibits endothelial activation, complement activation, and von Willebrand factor secretion in vitro and attenuates hyperacute rejection in an ex vivo model of pig-to-human pulmonary xenotransplantation. | Xenotransplantation 20080101 |
Apoptosis as a therapeutic target in heart failure. | American journal of physiology. Heart and circulatory physiology 20070901 |
A new evidence for DNA nicking property of amyloid beta-peptide (1-42): relevance to Alzheimer's disease. | Archives of biochemistry and biophysics 20070715 |
Biodegradable magnesium scaffolds: Part 1: appropriate inflammatory response. | Journal of biomedical materials research. Part A 20070601 |
Aurintricarboxylic acid inhibits protein synthesis independent, sanguinarine-induced apoptosis and oncosis. | Toxicologic pathology 20070201 |
Cortisol promotes survival and regeneration of axotomised retinal ganglion cells and enhances effects of aurintricarboxylic acid. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20061101 |
Oral gene delivery: design of polymeric carrier systems shielding toward intestinal enzymatic attack. | Biopolymers 20061101 |
Influence of the SCGE protocol on the amount of basal DNA damage detected in the Mediterranean mussel, Mytilus galloprovincialis. | Environmental and molecular mutagenesis 20061001 |
Biological evaluation, chelation, and molecular modeling studies of novel metal-chelating inhibitors of NF-kappaB-DNA binding: structure activity relationships. | Journal of medicinal chemistry 20060615 |
Post-treatment with the Ca(2+)-Mg(2+)-endonuclease inhibitor aurintricarboxylic acid prevents peroxynitrite-induced DNA damage and death of murine astrocytes. | Biochemical and biophysical research communications 20060609 |
Fusion and differentiation of murine C2C12 skeletal muscle cells that express Trichinella spiralis p43 protein. | Experimental parasitology 20060201 |
Paradoxical effects of aurintricarboxylic acid and RG-13577: acute thrombosis and in-stent stenosis in a passive-coated stent. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20060201 |
Dendritic supermolecules--towards controllable nanomaterials. | Chemical communications (Cambridge, England) 20060107 |
Salt is necessary for nucleosomal DNA fragmentation induced by caspase. | Biotechnology letters 20051201 |
Barriers to productive transfection of trabecular meshwork cells. | Molecular vision 20051026 |
Structural analysis of inhibition mechanisms of aurintricarboxylic acid on SARS-CoV polymerase and other proteins. | Computational biology and chemistry 20050601 |
Use of the nuclease inhibitor aurintricarboxylic acid (ATA) for improved non-viral intratumoral in vivo gene transfer by jet-injection. | The journal of gene medicine 20050401 |
Differential activation of heme oxygenase-1 by chalcones and rosolic acid in endothelial cells. | The Journal of pharmacology and experimental therapeutics 20050201 |
p66ShcA and ageing: modulation by longevity-promoting agent aurintricarboxylic acid. | Mechanisms of ageing and development 20050201 |
Coordinate involvement of cysteine protease and nuclease in the executive phase of plant apoptosis. | FEBS letters 20041217 |
Induction of apoptosis by benzamide and its inhibition by aurin tricarboxylic acid (ATA) in Chinese hamster V79 cells. | Mutation research 20041004 |
Aurintricarboxylic acid translocates across the plasma membrane, inhibits protein tyrosine phosphatase and prevents apoptosis in PC12 cells. | Molecules and cells 20040831 |
Potent and selective inhibition of SARS coronavirus replication by aurintricarboxylic acid. | Biochemical and biophysical research communications 20040806 |
Novel shift of Jak/Stat signalling characterizes the protective effect of aurintricarboxylic acid (ATA) from tumor necrosis factor-alpha toxicity in human B lymphocytes. | International journal of immunopathology and pharmacology 20040101 |
Enhanced systemic transgene expression after nonviral salivary gland transfection using a novel endonuclease inhibitor/DNA formulation. | Gene therapy 20031201 |
Mitigation of tumor necrosis factor alpha cytotoxicity by aurintricarboxylic acid in human peripheral B lymphocytes. | Biochemical pharmacology 20031115 |
Qbeta replicase discriminates between legitimate and illegitimate templates by having different mechanisms of initiation. | The Journal of biological chemistry 20031107 |
Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. | The Journal of biological chemistry 20031024 |
Inhibition of myocardial apoptosis reduces infarct size and improves regional contractile dysfunction during reperfusion. | Cardiovascular research 20030701 |
Transient reporter gene (GUS) expression in creeping bentgrass (Agrostis palustris) is affected by in vivo nucleolytic activity. | Biotechnology letters 20030601 |
Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells. | The Journal of biological chemistry 20030509 |
Hyperacute lung rejection in the pig-to-human model. III. Platelet receptor inhibitors synergistically modulate complement activation and lung injury. | Transplantation 20030415 |
[Resonance light scattering of aurintricarboxylic acid]. | Guang pu xue yu guang pu fen xi = Guang pu 20030201 |
Enhanced transport of a novel anti-HIV agent--cosalane and its congeners across human intestinal epithelial (Caco-2) cell monolayers. | International journal of pharmaceutics 20030102 |
Spontaneous DNA fragmentation in swim-up selected human spermatozoa during long term incubation. | Journal of andrology 20030101 |
Non-classic characteristics define prominent DNase activities from the intestine and other tissues of Haemonchus contortus. | Experimental parasitology 20030101 |
Inhibition of cytokine-induced JAK-STAT signalling pathways by an endonuclease inhibitor aurintricarboxylic acid. | British journal of pharmacology 20021201 |
Polymorphisms of glycoprotein Ib affect the inhibition by aurintricarboxylic acid of the von Willebrand factor dependent platelet aggregation. | Journal of molecular medicine (Berlin, Germany) 20021201 |
Electroporation in combination with a plasmid vector containing SV40 enhancer elements results in increased and persistent gene expression in mouse muscle. | Biochemical and biophysical research communications 20021108 |
Aurintricarboxylic acid attenuates intimal thickening after balloon injury of the rabbit aorta. | Thrombosis and haemostasis 20021001 |
Development of nonradioactive microtiter plate assays for nuclease activity. | Analytical biochemistry 20021001 |
Aluminum deposition in the bone of patients with chronic renal failure--detection of aluminum accumulation without signs of aluminum toxicity in bone using acid solochrome azurine. | Clinical nephrology 20021001 |
Aurintricarboxylic acid protects against cell death caused by lipopolysaccharide in macrophages by decreasing inducible nitric-oxide synthase induction via IkappaB kinase, extracellular signal-regulated kinase, and p38 mitogen-activated protein kinase inhibition. | Molecular pharmacology 20020701 |
Aurintricarboxylic acid induces a distinct activation of the IGF-I receptor signaling within MDA-231 cells. | Endocrinology 20020301 |
Modulation of apoptosis by mitochondrial uncouplers: apoptosis-delaying features despite intrinsic cytotoxicity. | Biochemical pharmacology 20020201 |
Intestinal absorption and biodistribution of cosalane and its amino acid conjugates: novel anti-HIV agents. | International journal of pharmaceutics 20020114 |
DNA transfection of macaque and murine respiratory tissue is greatly enhanced by use of a nuclease inhibitor. | The journal of gene medicine 20020101 |
[RNA, unlike DNA, binds to aurintricarboxylic acid via covalent bonds: molecular-biological and spectroscopic evidence]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101 |
Purification and characterization of a Bacillus subtilis 168 nuclease, YokF, involved in chromosomal DNA degradation and cell death caused by thermal shock treatments. | The Journal of biological chemistry 20011214 |
Effects of fibrinogen receptor antagonist GR144053F and aurintricarboxylic acid on platelet activation and degranulation. | Biochemical pharmacology 20011115 |
Synthesis and anti-HIV activity of cosalane analogues incorporating two dichlorodisalicylmethane pharmacophore fragments. | Bioorganic & medicinal chemistry 20011101 |
Perforated microelectrode arrays implanted in the regenerating adult central nervous system. | Experimental neurology 20010901 |
Activation of the insulin-like growth factor 1 signaling pathway by the antiapoptotic agents aurintricarboxylic acid and evans blue. | Endocrinology 20010701 |
Binding of cosalane--a novel highly lipophilic anti-HIV agent--to albumin and glycoprotein. | Journal of pharmaceutical sciences 20010501 |
Correlation of anti-HIV activity with anion spacing in a series of cosalane analogues with extended polycarboxylate pharmacophores. | Journal of medicinal chemistry 20010301 |
Pharmacological interventions of cyanide-induced cytotoxicity and DNA damage in isolated rat thymocytes and their protective efficacy in vivo. | Toxicology letters 20010203 |
Inhibition of RANTES/CCR1-mediated chemotaxis by cosalane and related compounds. | Bioorganic & medicinal chemistry letters 20010108 |
Aurintricarboxylic acid decreases proliferative potential of SKOV3 and MCF7 human carcinoma cells. | Anticancer research 20010101 |
Anti-HIV activity of a series of cosalane amino acid conjugates. | Bioorganic & medicinal chemistry letters 20001120 |
Identification of optimal anion spacing for anti-HIV activity in a series of cosalane tetracarboxylates. | Bioorganic & medicinal chemistry letters 20000918 |
Synthesis and anti-HIV activity of cosalane analogues incorporating nitrogen in the linker chain. | Bioorganic & medicinal chemistry 20000101 |
N-Nitrosodimethylamine-mediated cytotoxicity in a cell line expressing P450 2E1: evidence for apoptotic cell death. | Toxicology and applied pharmacology 19990601 |
The toxicity of 6-hydroxydopamine on PC12 and P19 cells. | Brain research. Molecular brain research 19990521 |
Extension of the polyanionic cosalane pharmacophore as a strategy for increasing anti-HIV potency. | Journal of medicinal chemistry 19990520 |
Synthesis of a cosalane analog with an extended polyanionic pharmacophore conferring enhanced potency as an anti-HIV agent. | Bioorganic & medicinal chemistry letters 19980407 |
Exploration of the effects of linker chain modifications on anti-HIV activities in a series of cosalane analogues. | Bioorganic & medicinal chemistry 19961001 |
Synthesis and biological evaluation of certain alkenyldiarylmethanes as anti-HIV-1 agents which act as non-nucleoside reverse transcriptase inhibitors. | Journal of medicinal chemistry 19960802 |
Correlation of anti-HIV potency with lipophilicity in a series of cosalane analogs having normal alkenyl and phosphodiester chains as cholestane replacements. | Journal of medicinal chemistry 19960119 |
Cosalane analogues with enhanced potencies as inhibitors of HIV-1 protease and integrase. | Journal of medicinal chemistry 19950203 |
Design, synthesis, and biological evaluation of cosalane, a novel anti-HIV agent which inhibits multiple features of virus reproduction. | Journal of medicinal chemistry 19940916 |
Inhibition of HIV-1 integration protein by aurintricarboxylic acid monomers, monomer analogs, and polymer fractions. | Biochemical and biophysical research communications 19920529 |
[The anti-HIV activity of beta-glycyrrhizic acid]. | Voprosy virusologii 19920101 |
Preparation and anti-HIV activities of aurintricarboxylic acid fractions and analogues: direct correlation of antiviral potency with molecular weight. | Journal of medicinal chemistry 19910101 |
Synthesis and anti-HIV activities of low molecular weight aurintricarboxylic acid fragments and related compounds. | Journal of medicinal chemistry 19910101 |
Aurintricarboxylic acid and Evans Blue represent two different classes of anionic compounds which selectively inhibit the cytopathogenicity of human T-cell lymphotropic virus type III/lymphadenopathy-associated virus. | Biochemical and biophysical research communications 19860414 |