Potential role for saccharopine reductase in swainsonine metabolism in endophytic fungus, Undifilum oxytropis.

Fungal biology 20120801

Synthesis and applications of masked oxo-sulfinamides in asymmetric synthesis.

Organic & biomolecular chemistry 20120714

Evaluation of a tandem gas chromatography/time-of-flight mass spectrometry metabolomics platform as a single method to investigate the effect of starvation on whole-animal metabolism in rainbow trout (Oncorhynchus mykiss).

The Journal of experimental biology 20120515

Exploration of pipecolate sulfonamides as binders of the FK506-binding proteins 51 and 52.

Journal of medicinal chemistry 20120510

Lysine catabolism in Haemonchus contortus and Teladorsagia circumcincta.

Experimental parasitology 20120501

Syntheses of (-)-pelletierine and (-)-homopipecolic acid.

Organic & biomolecular chemistry 20120407

Mechanism and optimisation of the homoboroproline bifunctional catalytic asymmetric aldol reaction: Lewis acid tuning through in situ esterification.

Organic & biomolecular chemistry 20120328

Stereoselective access to fluorinated and non-fluorinated quaternary piperidines: synthesis of pipecolic acid and iminosugar derivatives.

Chemistry (Weinheim an der Bergstrasse, Germany) 20120319

Occurrence of pipecolic acid and pipecolic acid betaine (homostachydrine) in Citrus genus plants.

Journal of agricultural and food chemistry 20120111

Synthesis and conformational analysis of efrapeptins.

Chemistry (Weinheim an der Bergstrasse, Germany) 20120109

Searching for novel anti-myotonic agents: pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide.

Neuromuscular disorders : NMD 20120101

Metabolic and proteomic profiling of diapause in the aphid parasitoid Praon volucre.

PloS one 20120101

The chemoselective reduction of isoxazoline γ-lactams through iminium Aza-Diels-Alder reactions: a short-cut synthesis of aminols as valuable intermediates towards nucleoside derivatives.

TheScientificWorldJournal 20120101

Re: Normalization of proliferation and tight junction formation in bladder epithelial cells from patients with interstitial cystitis/painful bladder syndrome by d-proline and d-pipecolic acid derivatives of antiproliferative factor.

The Journal of urology 20111201

Antiproliferative factor signaling and interstitial cystitis/painful bladder syndrome.

International neurourology journal 20111201

Responses to water stress of gas exchange and metabolites in Eucalyptus and Acacia spp.

Plant, cell & environment 20111001

2-Ethyl-piperidinium chloride.

Acta crystallographica. Section E, Structure reports online 20111001

(2,6-Difluoro-phen-yl)(4-methyl-piperidin-1-yl)methanone.

Acta crystallographica. Section E, Structure reports online 20110901

Ruthenium-catalysed synthesis of fluorinated bicyclic amino esters through tandem carbene addition/cyclopropanation of enynes.

Chemistry (Weinheim an der Bergstrasse, Germany) 20110816

Investigation of the biosynthesis of the pipecolate moiety of neuroprotective polyketide meridamycin.

The Journal of antibiotics 20110801

Metabolomic assessment with CE-MS of the nutraceutical effect of Cystoseira spp extracts in an animal model.

Electrophoresis 20110801

Biosynthetic chlorination of the piperazate residue in kutzneride biosynthesis by KthP.

Biochemistry 20110712

A one-pot, reductive amination/6-endo-trig cyclisation for the stereoselective synthesis of 6-substituted-4-oxopipecolic acids.

Chemical communications (Cambridge, England) 20110621

Metabolomics reveals attenuation of the SLC6A20 kidney transporter in nonhuman primate and mouse models of type 2 diabetes mellitus.

The Journal of biological chemistry 20110603

Normalization of proliferation and tight junction formation in bladder epithelial cells from patients with interstitial cystitis/painful bladder syndrome by d-proline and d-pipecolic acid derivatives of antiproliferative factor.

Chemical biology & drug design 20110601

Biomarkers aiding diagnosis of atypical presentation of pyridoxine-dependent epilepsy.

Pediatric neurology 20110401

[Application of liquid chromatography-mass spectrometry in the study of metabolic profiling of cirrhosis in different grades].

Se pu = Chinese journal of chromatography 20110401

Metabolomic analysis of livers and serum from high-fat diet induced obese mice.

Journal of proteome research 20110204

Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein.

Journal of medicinal chemistry 20110113

Metabonomic investigation of single and multiple strain Trypanosoma brucei brucei infections.

The American journal of tropical medicine and hygiene 20110105

Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I.

Brain : a journal of neurology 20110101

Metabolomic correlation-network modules in Arabidopsis based on a graph-clustering approach.

BMC systems biology 20110101

Autosomal recessive cerebellar ataxia caused by mutations in the PEX2 gene.

Orphanet journal of rare diseases 20110101

A simple and highly sensitive HPLC method with fluorescent detection for determination of pipecolic acid in mouse brain areas.

Biological & pharmaceutical bulletin 20110101

6-Azido-3-O-benzyl-6-de-oxy-N,N-diethyl-1,2-O-isopropyl-idene-d-glycero-α-d-gluco-heptofuran-uronamide.

Acta crystallographica. Section E, Structure reports online 20110101

Pyridoxine dependent epilepsy and antiquitin deficiency: clinical and molecular characteristics and recommendations for diagnosis, treatment and follow-up.

Molecular genetics and metabolism 20110101

Diffusion-weighted Magnetic Resonance Imaging in the Early Diagnosis of Neonatal Adrenoleukodystrophy.

Journal of clinical imaging science 20110101

Global host metabolic response to Plasmodium vivax infection: a 1H NMR based urinary metabonomic study.

Malaria journal 20110101

Defining the plant peroxisomal proteome: from Arabidopsis to rice.

Frontiers in plant science 20110101

Synthesis of methyl N-Boc-(2S,4R)-4-methylpipecolate.

The Journal of organic chemistry 20101217

Structures of cyclic dipeptides: an X-ray and computational study of cis- and trans-cyclo(Pip-Phe), cyclo(Pro-Phe) and their N-methyl derivatives.

Acta crystallographica. Section B, Structural science 20101201

Intramolecular hydroamination of dithioketene acetals: an easy route to cyclic amino acid derivatives.

Organic letters 20101119

Is β-homo-proline a pseudo-γ-turn forming element of β-peptides? An IR and VCD spectroscopic study on Ac-β-HPro-NHMe in cryogenic matrices and solutions.

Physical chemistry chemical physics : PCCP 20101107

[Drug development from natural fermentation products: establishing a manufacturing process which maximizes the potential of microorganisms].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101101

Diversity-oriented synthesis of cyclic acyldepsipeptides leads to the discovery of a potent antibacterial agent.

Bioorganic & medicinal chemistry 20101015

Highly enantioselective catalytic dynamic resolution of N-Boc-2-lithiopiperidine: synthesis of (R)-(+)-N-Boc-pipecolic acid, (S)-(-)-coniine, (S)-(+)-pelletierine, (+)-beta-conhydrine, and (S)-(-)-ropivacaine and formal synthesis of (-)-lasubine II and (+)-cermizine C.

Journal of the American Chemical Society 20100908

Biosynthesis of rapamycin and its regulation: past achievements and recent progress.

The Journal of antibiotics 20100801

Diastereoselective intramolecular additions of allyl- and propargylsilanes to iminium ions: synthesis of cyclic and bicyclic quaternary amino acids.

Organic letters 20100702

LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis.

Plant physiology 20100701

Genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy (ALDH7A1 deficiency).

Brain : a journal of neurology 20100701

Solar salt lake as natural environmental source for extraction halophilic pigments.

Iranian journal of microbiology 20100601

Integrated cytokine and metabolic analysis of pathological responses to parasite exposure in rodents.

Journal of proteome research 20100507

Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria.

The Plant cell 20100501

Discovery of 23 natural tubulysins from Angiococcus disciformis An d48 and Cystobacter SBCb004.

Chemistry & biology 20100326

Intramolecular anodic olefin coupling reactions and the synthesis of cyclic amines.

Journal of the American Chemical Society 20100303

Determination of pipecolic acid following trimethylsilyl and trifluoroacyl derivatisation on plasma filter paper by stable isotope GC-MS for peroxisomal disorders.

Archives of pharmacal research 20100201

Metabolism of lysine in alpha-aminoadipic semialdehyde dehydrogenase-deficient fibroblasts: evidence for an alternative pathway of pipecolic acid formation.

FEBS letters 20100104

The vinylfluoro group as an acetonyl cation equivalent: stereoselective synthesis of 6-substituted 4-hydroxy pipecolic acid derivatives.

The Journal of organic chemistry 20100101

Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression.

Malaria journal 20100101

Structural and transcriptional analysis of plant genes encoding the bifunctional lysine ketoglutarate reductase saccharopine dehydrogenase enzyme.

BMC plant biology 20100101

Antineoplastic Activity of New Transition Metal Complexes of 6-Methylpyridine-2-carbaldehyde-N(4)-ethylthiosemicarbazone: X-Ray Crystal Structures of [VO(2)(mpETSC)] and [Pt(mpETSC)Cl].

Bioinorganic chemistry and applications 20100101

Chronic myeloid leukemia patients sensitive and resistant to imatinib treatment show different metabolic responses.

PloS one 20100101

Antiviral lead compounds from marine sponges.

Marine drugs 20100101

Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease.

International journal of Alzheimer's disease 20100101

Potential anti-HIV agents from marine resources: an overview.

Marine drugs 20100101

Bioactive dehydrotyrosyl and dehydrodopyl compounds of marine origin.

Marine drugs 20100101

Methyl 9-p-tolyl-8a,9,9a,10,11,12,13,14a-octa-hydro-8H-benzo[f]chromeno[3,4-b]indolizine-8a-carboxyl-ate.

Acta crystallographica. Section E, Structure reports online 20091201

Simultaneous determination of alpha-aminoadipic semialdehyde, piperideine-6-carboxylate and pipecolic acid by LC-MS/MS for pyridoxine-dependent seizures and folinic acid-responsive seizures.

Journal of neuroscience methods 20091030

(2S,3R,4R,5R)-3,4-Dihydr-oxy-5-(hydroxy-meth-yl)pyrrolidine-2-carboxylic acid [(2S,3R,4R,5R)-3,4-dihydr-oxy-5-(hydroxy-meth-yl)proline].

Acta crystallographica. Section E, Structure reports online 20091001

Methyl 9-(4-bromo-phen-yl)-8a,9,9a,10,11,12,13,14a-octa-hydro-8H-benzo[f]chromeno[3,4-b]indolizine-8a-car-box-ylate.

Acta crystallographica. Section E, Structure reports online 20091001

Methyl 5-phenyl-1,2,3,4,4a,5,5a,13c-octahydro-6H-benzo[f]chromeno[3,4-b]indolizine-5a-carboxyl-ate.

Acta crystallographica. Section E, Structure reports online 20090801

Synthesis of alpha-cyclopropyl-beta-homoprolines.

The Journal of organic chemistry 20090605

Prevalence of ALDH7A1 mutations in 18 North American pyridoxine-dependent seizure (PDS) patients.

Epilepsia 20090501

Folinic acid-responsive seizures are identical to pyridoxine-dependent epilepsy.

Annals of neurology 20090501

Recent advances in the chemistry, biosynthesis and pharmacology of rapamycin analogs.

Natural product reports 20090501

Effect of a carboxyl group on the chemiluminescent reaction of tris(2,2'-bipyridine)ruthenium(III) with aliphatic amines.

Talanta 20090415

Analogues of AVP modified in the N-terminal part of the molecule with Pip isomers: TFA-catalysed peptide bond hydrolysis.

Journal of peptide science : an official publication of the European Peptide Society 20090301

A PEX10 defect in a patient with no detectable defect in peroxisome assembly or metabolism in cultured fibroblasts.

Journal of inherited metabolic disease 20090201

7-Azido-N,N-diethyl-4,5-O-isopropyl-idene-4-C-methyl-3,6-anhydro-7-de-oxy-d-glycero-d-manno-heptonamide.

Acta crystallographica. Section E, Structure reports online 20090201

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nature chemical biology 20090101

Analogues of arginine vasopressin modified in the N-terminal part of the molecule with pipecolic acid isomers.

Advances in experimental medicine and biology 20090101

Metabolite signal identification in accurate mass metabolomics data with MZedDB, an interactive m/z annotation tool utilising predicted ionisation behaviour 'rules'.

BMC bioinformatics 20090101

LKR/SDH plays important roles throughout the tick life cycle including a long starvation period.

PloS one 20090101

N-ethoxycarbonylation combined with (S)-1-phenylethylamidation for enantioseparation of amino acids by achiral gas chromatography and gas chromatography-mass spectrometry.

Journal of chromatography. A 20081219

Characterization of a 7.6-Mb germline deletion encompassing the NF1 locus and about a hundred genes in an NF1 contiguous gene syndrome patient.

European journal of human genetics : EJHG 20081201

[Chemical constituents from Faeces bombycis].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081101

The practice of ring constraint in peptidomimetics using bicyclic and polycyclic amino acids.

Accounts of chemical research 20081001

Pyridoxine-dependent epilepsy: normal outcome in a patient with late diagnosis after prolonged status epilepticus causing cortical blindness.

Neuropediatrics 20081001

Stereoselective synthesis of 2,4,5-trisubstituted piperidines by carbonyl ene and Prins cyclisations.

Organic & biomolecular chemistry 20080921

Diastereoselective functionalizations of enecarbamates derived from pipecolic acid towards 5-guanidinopipecolates as arginine mimetics.

Organic & biomolecular chemistry 20080921

Global metabolic responses of NMRI mice to an experimental Plasmodium berghei infection.

Journal of proteome research 20080901

Mechanistic studies of amide bond scission during acidolytic deprotection of Pip containing peptide.

Journal of peptide science : an official publication of the European Peptide Society 20080801

Improved protocol for asymmetric, intramolecular heteroatom Michael addition using organocatalysis: enantioselective syntheses of homoproline, pelletierine, and homopipecolic acid.

The Journal of organic chemistry 20080704

Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery.

PLoS neglected tropical diseases 20080701

Investigational methods for peroxisomal disorders.

Current protocols in human genetics 20080701

A liquid chromatography-quadrupole time-of-flight (LC-QTOF)-based metabolomic approach reveals new metabolic effects of catechin in rats fed high-fat diets.

Journal of proteome research 20080601

The peroxisome: still a mysterious organelle.

Histochemistry and cell biology 20080401

A novel yellow pigment, furpipate, derived from lysine and furfural.

Annals of the New York Academy of Sciences 20080401

Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress.

Free radical biology & medicine 20080215

Synthesis, Spectroscopic, and Anticancerous Properties of Mixed Ligand Palladium(II) and Silver(I) Complexes with 4,6-Diamino-5-hydroxy-2-mercaptopyrimidine and 2,2'-Bipyridyl.

Metal-based drugs 20080101

Total synthesis studies on macrocyclic pipecolic acid natural products: FK506, the antascomicins and rapamycin.

Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20080101

Organocatalytic enantioselective synthesis of highly functionalized polysubstituted pyrrolidines.

Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

An insight into the biochemistry of inborn errors of metabolism for a clinical neurologist.

Annals of Indian Academy of Neurology 20080101

Functional analysis of genes encoding putative oxidoreductases in Aspergillus oryzae, which are similar to fungal fructosyl-amino acid oxidase.

Journal of bioscience and bioengineering 20071101

Pyridoxine-dependent seizures in Dutch patients: diagnosis by elevated urinary alpha-aminoadipic semialdehyde levels.

Archives of disease in childhood 20070801

Allelic and non-allelic heterogeneities in pyridoxine dependent seizures revealed by ALDH7A1 mutational analysis.

Molecular genetics and metabolism 20070801

Browning of furfural and amino acids, and a novel yellow compound, furpipate, formed from lysine and furfural.

Bioscience, biotechnology, and biochemistry 20070701

Therapeutic cloning: promises and issues.

McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students 20070701

Synthesis and biological activity of oxytocin analogues containing conformationally-restricted residues in position 7.

European journal of medicinal chemistry 20070601

Biochemical characterisation of recombinant Streptomyces pristinaespiralis L-lysine cyclodeaminase.

Biochimie 20070501

Potent and selective agonists of alpha-melanotropin (alphaMSH) action at human melanocortin receptor 5; linear analogs of alpha-melanotropin.

Peptides 20070501

Potent and selective peptide agonists of alpha-melanocyte stimulating hormone (alphaMSH) action at human melanocortin receptor 5; their synthesis and biological evaluation in vitro.

Chemical biology & drug design 20070501

Stereochemical and skeletal diversity employing pipecolate ester scaffolds.

Organic letters 20070412

Conformational preferences of proline analogues with different ring size.

The journal of physical chemistry. B 20070405

Mechanistic aspects and redox properties of hyperthermophilic L-proline dehydrogenase from Pyrococcus furiosus related to dimethylglycine dehydrogenase/oxidase.

The FEBS journal 20070401

An efficient synthesis of enantiomerically pure (R)-pipecolic acid, (S)-proline, and their N-alkylated derivatives.

The Journal of organic chemistry 20070302

Highly sensitive and simple method for measurement of pipecolic acid using reverse-phase ion-pair high performance liquid chromatography with tris(2,2'-bipyridine)ruthenium(III) chemiluminescence detection.

Journal of chromatography. A 20070126

Biochemical and molecular characterization of 18 patients with pyridoxine-dependent epilepsy and mutations of the antiquitin (ALDH7A1) gene.

Human mutation 20070101

Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for self-renewal.

BMC developmental biology 20070101

Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana.

BMC systems biology 20070101

Peroxisome biogenesis disorders.

Biochimica et biophysica acta 20061201

Convergent synthesis of complex diketopiperazines derived from pipecolic acid scaffolds and parallel screening against GPCR targets.

The Journal of organic chemistry 20061110

European Academy of Paediatrics, Barcelona, Spain, October 7-10, 2006. Abstracts.

European journal of pediatrics 20061101

Enzymatic synthesis of L-pipecolic acid by Delta1-piperideine-2-carboxylate reductase from Pseudomonas putida.

Bioscience, biotechnology, and biochemistry 20060901

High-performance liquid chromatographic enantioseparation of unusual secondary amino acids on a D-penicillamine-based chiral ligand exchange column.

Chirality 20060801

Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.

Gene 20060801

Proline/pipecolinic acid-promoted copper-catalyzed P-arylation.

The Journal of organic chemistry 20060623

Pipecolic acid in microbes: biosynthetic routes and enzymes.

Journal of industrial microbiology & biotechnology 20060601

Succinate-mediated catabolite repression control on the production of glycine betaine catabolic enzymes in Pseudomonas aeruginosa PAO1 under low and elevated salinities.

Microbiology (Reading, England) 20060501

[Development of highly sensitive determination of biogenic compounds by high-performance liquid chromatography with pre-column fluorescence derivatization].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060501

Structure determination of neoefrapeptins A to N: peptides with insecticidal activity produced by the fungus Geotrichum candidum.

The Journal of antibiotics 20060501

Pyridoxine-dependent seizures: new genetic and biochemical clues to help with diagnosis and treatment.

Current opinion in neurology 20060401

The special five-membered ring of proline: An experimental and theoretical investigation of alkali metal cation interactions with proline and its four- and six-membered ring analogues.

The journal of physical chemistry. A 20060323

Biosynthesis of pipecolic acid by RapL, a lysine cyclodeaminase encoded in the rapamycin gene cluster.

Journal of the American Chemical Society 20060322

Pipecolic acid-catalyzed direct asymmetric mannich reactions.

Organic letters 20060302

Synthesis and pharmacochemical study of novel polyfunctional molecules combining anti-inflammatory, antioxidant, and hypocholesterolemic properties.

Bioorganic & medicinal chemistry letters 20060215

The lysine-ketoglutarate reductase-saccharopine dehydrogenase is involved in the osmo-induced synthesis of pipecolic acid in rapeseed leaf tissues.

Plant physiology and biochemistry : PPB 20060101

Pipecolic acid: a diagnostic marker in pyridoxine-dependent epilepsy.

Annals of neurology 20051001

Dual catalyst control in the enantioselective intramolecular Morita-Baylis-Hillman reaction.

Organic letters 20050901

Three-component synthesis of polysubstituted homoproline analogs.

Molecules (Basel, Switzerland) 20050831

Recent advances in asymmetric synthesis of pipecolic acid and derivatives.

Amino acids 20050801

Synthesis of pipecolic acid-based spiro bicyclic lactam scaffolds as beta-turn mimics.

The Journal of organic chemistry 20050722

Synthesis of a pipecolic acid-based bis-amino acid and its assembly into a spiro ladder oligomer.

Organic letters 20050707

Pipecolic acid as a diagnostic marker of pyridoxine-dependent epilepsy.

Neuropediatrics 20050601

Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme.

Biochemistry 20050426

Molecular cloning of the mouse IMINO system: an Na+- and Cl--dependent proline transporter.

The Biochemical journal 20050315

Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino.

The Journal of biological chemistry 20050311

Synthesis and biological evaluation of new GABA-uptake inhibitors derived from proline and from pyrrolidine-2-acetic acid.

European journal of medicinal chemistry 20050301

Mutations of ousA alter the virulence of Erwinia chrysanthemi.

Molecular plant-microbe interactions : MPMI 20050201

Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene.

Journal of biomedicine & biotechnology 20050101

Pipecolic acid concentrations in brain tissue of nutritionally pyridoxine-deficient rats.

Journal of inherited metabolic disease 20050101

The metabolic profiles of transgenic cucumber lines vary with different chromosomal locations of the transgene.

Cellular & molecular biology letters 20050101

Characterization and crystal structure of cadmium(II) halide complexes with amino acids and their derivatives VI. The comparison of crystal structures of cadmium(II) halide complexes with three kinds of piperidine carboxylic acids.

Journal of inorganic biochemistry 20041201

The effects of seed quality and pipecolic and djenkolic acids on bruchid beetle infestation in water deficit-stressed Acacia trees.

Journal of chemical ecology 20041101

Hyperpipecolic acidaemia: a diagnostic tool for peroxisomal disorders.

Molecular genetics and metabolism 20040701

Quantitation of hydroxyproline in bone by gas chromatography-mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040525

New amperometric biosensors based on diamond paste for the assay of L- and D-pipecolic acids in serum samples.

Preparative biochemistry & biotechnology 20040501

Characterization and metabolic function of a peroxisomal sarcosine and pipecolate oxidase from Arabidopsis.

The Journal of biological chemistry 20040423

Applications of the ninhydrin reaction for analysis of amino acids, peptides, and proteins to agricultural and biomedical sciences.

Journal of agricultural and food chemistry 20040211

Pathogenesis of peroxisomal deficiency disorders (Zellweger syndrome) may be mediated by misregulation of the GABAergic system via the diazepam binding inhibitor.

BMC pediatrics 20040101

Synthesis, molecular modeling and biological evaluation of aza-proline and aza-pipecolic derivatives as FKBP12 ligands and their in vivo neuroprotective effects.

Bioorganic & medicinal chemistry 20031103

Discrimination between arabica and robusta coffee species on the basis of their amino acid enantiomers.

Journal of agricultural and food chemistry 20031022

Central pipecolic acid increases food intake under ad libitum feeding conditions in the neonatal chick.

Neuroscience letters 20030821

Pipecolic acid induces apoptosis in neuronal cells.

Brain research 20030808

Intracerebroventricular administration of GABA-A and GABA-B receptor antagonists attenuate feeding and sleeping-like behavior induced by L-pipecolic acid in neonatal chicks.

Journal of neuroscience research 20030715

Structure determination of glycinocins A to D, further evidence for the cyclic structure of the amphomycin antibiotics.

The Journal of antibiotics 20030601

Pyridoxine-dependent seizures: a clinical and biochemical conundrum.

Biochimica et biophysica acta 20030411

Photoinduced chemical reactions on natural single crystals and synthesized crystallites of mercury(II) sulfide in aqueous solution containing naturally occurring amino acids.

Inorganic chemistry 20030310

Functionalized cis- and trans-fused bicyclic alpha-amino acids via stereoselective double annulation and dequaternization reactions.

The Journal of organic chemistry 20030221

Structure-activity relationships of dynorphin analogs substituted in positions 2 and 3.

Biopolymers 20030101

Determination of D- and L-pipecolic acid in food samples including processed foods.

Annals of nutrition & metabolism 20030101

Plasma pipecolic acid is frequently elevated in non-peroxisomal disease.

Journal of inherited metabolic disease 20021201

[Innovative molecular transformation using optically active alpha-amino acids].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20021101

Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.

Journal of natural products 20021101

Glutaric aciduria type III: a distinctive non-disease?

Journal of inherited metabolic disease 20021001

High-performance liquid chromatography determination of pipecolic acid after precolumn ninhydrin derivatization using domestic microwave.

Analytical biochemistry 20020915

Increase in the rate of L-pipecolic acid production using lat-expressing Escherichia coli by lysP and yeiE amplification.

Bioscience, biotechnology, and biochemistry 20020901

Synthesis of N-glyoxyl prolyl and pipecolyl amides and thioesters and evaluation of their in vitro and in vivo nerve regenerative effects.

Journal of medicinal chemistry 20020801

A pipecolic acid (Pip)-containing dipeptide, Boc-D-Ala-L-Pip-NH(i)Pr.

Acta crystallographica. Section C, Crystal structure communications 20020701

A novel near-infrared fluorescence sensor for detection of thrombin activation in blood.

Chembiochem : a European journal of chemical biology 20020301

Biotransformation of L-lysine to L-pipecolic acid catalyzed by L-lysine 6-aminotransferase and pyrroline-5-carboxylate reductase.

Bioscience, biotechnology, and biochemistry 20020301

Application of a new chiral derivatizing agent to the enantioseparation of secondary amino acids.

Journal of chromatography. A 20020301

Kinetics of binding of [(3)H]glycine to transport proteins in channel catfish brain.

Neuro-Signals 20020101

Determination of L-pipecolic acid in plasma using chiral liquid chromatography-electrospray tandem mass spectrometry.

Clinical chemistry 20011201

Intracerebroventricular injection of pipecolic acid inhibits food intake and induces sleeping-like behaviors in the neonatal chick.

Neuroscience letters 20010914

A heterocycle-forming double michael reaction. [5 + 1] annulation route to highly substituted and functionalized piperidines.

Organic letters 20010906

A short synthesis of argatroban. a potent selective thrombin inhibitor.

Bioorganic & medicinal chemistry letters 20010806

Cyclic hydroxamic-acid-containing peptide 31, a potent synthetic histone deacetylase inhibitor with antitumor activity.

Cancer research 20010601

Masked oxo sulfinimines (N-sulfinyl imines) in the asymmetric synthesis of proline and pipecolic acid derivatives.

Organic letters 20010308

Synthesis and structure-activity relationships of potential anticonvulsants based on 2-piperidinecarboxylic acid and related pharmacophores.

European journal of medicinal chemistry 20010301

Deletion of rapQONML from the rapamycin gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog.

The Journal of antibiotics 20010301

A family of depsi-peptide fungal metabolites, as selective and competitive human tachykinin receptor (NK2) antagonists: fermentation, isolation, physico-chemical properties, and biological activity.

The Journal of antibiotics 20010201

Zellweger syndrome: report of one case.

Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi 20010101

Molecular cloning and expression of human L-pipecolate oxidase.

Biochemical and biophysical research communications 20000421

L-Pipecolic acid oxidase, a human enzyme essential for the degradation of L-pipecolic acid, is most similar to the monomeric sarcosine oxidases.

The Biochemical journal 20000201

Cloning and functional expression of a mammalian gene for a peroxisomal sarcosine oxidase.

The Journal of biological chemistry 19970307

Substitution of proline with pipecolic acid at the scissile bond converts a peptide substrate of HIV proteinase into a selective inhibitor.

Biochemical and biophysical research communications 19900531