Home Carboxys Phosphinecarboxylic acid, dihydroxy-, oxide, trisodium salt

Phosphinecarboxylic acid, dihydroxy-, oxide, trisodium salt

CAS No.:
63585-09-1
Catalog Number:
AG01DN8O
Molecular Formula:
CNa3O5P
Molecular Weight:
191.9508
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
≥98%
1 week
United States
$103
- +
500mg
≥98%
1 week
United States
$139
- +
1g
≥98%
1 week
United States
$185
- +
5g
≥98%
1 week
United States
$561
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Product Description
Catalog Number:
AG01DN8O
Chemical Name:
Phosphinecarboxylic acid, dihydroxy-, oxide, trisodium salt
CAS Number:
63585-09-1
Molecular Formula:
CNa3O5P
Molecular Weight:
191.9508
MDL Number:
MFCD03936173
IUPAC Name:
trisodium;phosphonatoformate
InChI:
InChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3
InChI Key:
DFHAXXVZCFXGOQ-UHFFFAOYSA-K
SMILES:
[O-]C(=O)P(=O)([O-])[O-].[Na+].[Na+].[Na+]
UNII:
8C5OQ81LWT
Properties
Complexity:
103  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
4  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
191.918g/mol
Formal Charge:
0
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
191.949g/mol
Monoisotopic Mass:
191.918g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
103A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
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[A novel colorimetric test to study the susceptibility of human cytomegalovirus DNA polymerase to foscarnet]. Pathologie-biologie 20050101
Progressive outer retinal necrosis presenting with isolated optic neuropathy. Neurology 20041228
Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet. Bioorganic & medicinal chemistry letters 20041206
Use of leflunomide in an allogeneic bone marrow transplant recipient with refractory cytomegalovirus infection. Bone marrow transplantation 20041201
Drug-induced renal failure in the ICU. The International journal of artificial organs 20041201
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A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus retinitis. Antiviral research 20041101
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Efficacy of 5-vinyl-1-beta-D-arabinofuranosyluracil (VaraU) against herpes simplex virus type 2 strains in cell cultures and against experimental herpes encephalitis in mice: comparison with acyclovir and foscarnet. Pharmaceutical research 19870601
Synthesis and antiviral activity of certain nucleoside 5'-phosphonoformate derivatives. Journal of medicinal chemistry 19860801
Comparison of foscarnet cream, acyclovir cream, and acyclovir ointment in the topical treatment of experimental cutaneous herpes simplex virus type 1 infection. Antimicrobial agents and chemotherapy 19860701
Synergistic inhibition of human T-cell lymphotropic virus type III replication in vitro by phosphonoformate and recombinant alpha-A interferon. Antimicrobial agents and chemotherapy 19860701
PPi analogs as inhibitors of human T-lymphotropic virus type III reverse transcriptase. Antimicrobial agents and chemotherapy 19860501
Inhibition of herpes simplex virus DNA polymerase by purine ribonucleoside monophosphates. The Journal of biological chemistry 19860205
Inhibition of HTLV-III/LAV replication by foscarnet. Biochemical pharmacology 19851115
5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. Journal of medicinal chemistry 19851101
Inhibition of human T-cell lymphotropic virus type III in vitro by phosphonoformate. Lancet (London, England) 19850629
Combination chemotherapy: interaction of 5-methoxymethyldeoxyuridine with trifluorothymidine, phosphonoformate and acycloguanosine against herpes simplex viruses. Antiviral research 19850201
Synthesis of esters of phosphonoformic acid and their antiherpes activity. Journal of medicinal chemistry 19830201
Antiviral effects of phosphonoformate (PFA, foscarnet sodium). Pharmacology & therapeutics 19820101
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