Home Other Building Blocks Polyhexamethyleneguanidine HCl

Polyhexamethyleneguanidine HCl

CAS No.:
57028-96-3
Catalog Number:
AG01EADG
Molecular Formula:
Molecular Weight:
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Product Description
Catalog Number:
AG01EADG
Chemical Name:
Polyhexamethyleneguanidine HCl
CAS Number:
57028-96-3
MDL Number:
MFCD01742716
IUPAC Name:
1,2-dibutylguanidine
InChI:
InChI=1S/C9H21N3/c1-3-5-7-11-9(10)12-8-6-4-2/h3-8H2,1-2H3,(H3,10,11,12)
InChI Key:
HXEJAEDEMWCUTP-UHFFFAOYSA-N
Properties
Complexity:
121  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
171.174g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
171.288g/mol
Monoisotopic Mass:
171.174g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
50.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.6  
Literature
Title Journal
MicroRNA regulatory networks reflective of polyhexamethylene guanidine phosphate-induced fibrosis in A549 human alveolar adenocarcinoma cells. Toxicology letters 20180501
Lung fibroblasts may play an important role in clearing apoptotic bodies of bronchial epithelial cells generated by exposure to PHMG-P-containing solution. Toxicology letters 20180401
Changes in expression of cytokines in polyhexamethylene guanidine-induced lung fibrosis in mice: Comparison of bleomycin-induced lung fibrosis. Toxicology 20180115
Polyhexamethylene guanidine phosphate induces IL-6 and TNF-α expression through JNK-dependent pathway in human lung epithelial cells. The Journal of toxicological sciences 20180101
Analysis of genomic responses in a rat lung model treated with a humidifier sterilizer containing polyhexamethyleneguanidine phosphate. Toxicology letters 20170215
Polyhexamethylene guanidine phosphate aerosol particles induce pulmonary inflammatory and fibrotic responses. Archives of toxicology 20160301
Humidifier Disinfectants Are a Cause of Lung Injury among Adults in South Korea: A Community-Based Case-Control Study. PloS one 20160101
The role of NF-κB signaling pathway in polyhexamethylene guanidine phosphate induced inflammatory response in mouse macrophage RAW264.7 cells. Toxicology letters 20150304
Polyhexamethyleneguanidine phosphate induces severe lung inflammation, fibrosis, and thymic atrophy. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140701
Cytotoxicity and gene expression profiling of polyhexamethylene guanidine hydrochloride in human alveolar A549 cells. Toxicology in vitro : an international journal published in association with BIBRA 20140601
Exposure characteristics of familial cases of lung injury associated with the use of humidifier disinfectants. Environmental health : a global access science source 20140101
Interactions of biocidal guanidine hydrochloride polymer analogs with model membranes: a comparative biophysical study. Acta biochimica et biophysica Sinica 20110901
Acute cholestatic liver injury caused by polyhexamethyleneguanidine hydrochloride admixed to ethyl alcohol. Clinical toxicology (Philadelphia, Pa.) 20110701
The toxicity lies not with the alcohol, but with the mixers. Clinical toxicology (Philadelphia, Pa.) 20110701
Damage of Escherichia coli membrane by bactericidal agent polyhexamethylene guanidine hydrochloride: micrographic evidences. Journal of applied microbiology 20100301
[Forensic chemical investigation of alcohol-containing liquids contained polyhexamethylene guanidine hydrochloride and diethylphthalate]. Sudebno-meditsinskaia ekspertiza 20100101
Polyhexamethylene guanidine hydrochloride-based disinfectant: a novel tool to fight meticillin-resistant Staphylococcus aureus and nosocomial infections. Journal of medical microbiology 20081201
[Forensic-medical evaluation of toxic hepatitis associated with surrogate alcohol poisoning]. Sudebno-meditsinskaia ekspertiza 20080101
[Characteristics of polyamine biosynthesis regulation and tumor growth rate in hormone-dependant grafted breast tumors of mice and rats]. Likars'ka sprava 20070101
[Comparative analysis of antimicrobial action of polyhexametylenguanide hydrochloride (Biopag) and chlorhexidine bigluconate upon potential infectious agent of suppurative-inflammatory diseases of maxillo-facial region and neck]. Stomatologiia 20070101
[Effect of alpha-difluoromethylornithine and polyhexamethyleneguanidine (PMG), polyamine biosynthesis inhibitors on leucosis L1210 growth kinetics and life expectancy of animals with cancer]. Likars'ka sprava 20051201
A comparative study of characteristics of current-type and conventional-type cationic bactericides. Biological & pharmaceutical bulletin 20010901
Properties