[1,1'-Biphenyl]-4-acetic acid, 2-fluoro-a-methyl-, (±)-
| Title | Journal |
|---|---|
| Discovery of Novel 15-Lipoxygenase Activators To Shift the Human Arachidonic Acid Metabolic Network toward Inflammation Resolution. | Journal of medicinal chemistry 20160512 |
| Potent multitarget FAAH-COX inhibitors: Design and structure-activity relationship studies. | European journal of medicinal chemistry 20160215 |
| Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | Chemical research in toxicology 20150518 |
| CYP2C9 genotype vs. metabolic phenotype for individual drug dosing--a correlation analysis using flurbiprofen as probe drug. | PloS one 20150101 |
| CYP2C19 polymorphisms account for inter-individual variability of drug metabolism in cynomolgus macaques. | Biochemical pharmacology 20140915 |
| A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | Toxicological sciences : an official journal of the Society of Toxicology 20140101 |
| CHF5074 reduces biomarkers of neuroinflammation in patients with mild cognitive impairment: a 12-week, double-blind, placebo-controlled study. | Current Alzheimer research 20130901 |
| Fatal hypersensitivity reaction to an oral spray of flurbiprofen: a case report. | Journal of clinical pharmacy and therapeutics 20130801 |
| Implication of novel CYP2C9*57 (p.Asn204His) variant in coumarin hypersensitivity. | Thrombosis research 20130601 |
| Use of micropatterned cocultures to detect compounds that cause drug-induced liver injury in humans. | Toxicological sciences : an official journal of the Society of Toxicology 20130301 |
| Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking. | Journal of molecular modeling 20121201 |
| Study of the solvent effects on the molecular structure and CO stretching vibrations of flurbiprofen. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201 |
| Pomegranate juice and pomegranate extract do not impair oral clearance of flurbiprofen in human volunteers: divergence from in vitro results. | Clinical pharmacology and therapeutics 20121101 |
| Non-selective inhibition of cyclooxygenase enzymes by aminoacetylenic isoindoline 1,3-diones. | Inflammation & allergy drug targets 20121001 |
| Stereoselective binding of flurbiprofen enantiomers and their methyl esters to human serum albumin studied by time-resolved phosphorescence. | Chirality 20121001 |
| Flurbiprofen axetil promotes neuroprotection by activation of cerebral peroxisome proliferator-activated receptor gamma after focal cerebral ischemia in rats. | Chinese medical journal 20121001 |
| Effect of temperature, cosolvent, and added drug on Pluronic-flurbiprofen micellization. | The journal of physical chemistry. B 20120920 |
| 3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3. | Journal of medicinal chemistry 20120913 |
| Excited-state interactions in diastereomeric flurbiprofen-thymine dyads. | The journal of physical chemistry. A 20120906 |
| Transglycosylated rutin-specific non-surface-active nanostructure affects absorption enhancement of flurbiprofen. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120901 |
| Formulation, evaluation and pharmacokinetics of colon targeted pulsatile system of flurbiprofen. | Journal of drug targeting 20120901 |
| Drug-induced TINU syndrome and genetic characterization. | Clinical nephrology 20120901 |
| Flurbiprofen axetil provides a prophylactic benefit against mesenteric traction syndrome associated with remifentanil infusion during laparotomy. | Journal of anesthesia 20120801 |
| Effect of P450 oxidoreductase variants on the metabolism of model substrates mediated by CYP2C9.1, CYP2C9.2, and CYP2C9.3. | Pharmacogenetics and genomics 20120801 |
| Intra-articular delivery of genipin cross-linked chitosan microspheres of flurbiprofen: preparation, characterization, in vitro and in vivo studies. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120801 |
| Non-steroidal anti-inflammatory drugs reduce the stress response during sevoflurane anesthesia. | Acta anaesthesiologica Scandinavica 20120801 |
| Nano-pulverization of poorly water soluble compounds with low melting points by a rotation/revolution pulverizer. | Die Pharmazie 20120801 |
| Modulation of drug release from nanocarriers loaded with a poorly water soluble drug (flurbiprofen) comprising natural waxes. | Die Pharmazie 20120801 |
| Beyond benzyl grignards: facile generation of benzyl carbanions from styrenes. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120723 |
| Simultaneously improving the mechanical properties, dissolution performance, and hygroscopicity of ibuprofen and flurbiprofen by cocrystallization with nicotinamide. | Pharmaceutical research 20120701 |
| Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. | European journal of medicinal chemistry 20120701 |
| Comparative study of three methods for affinity measurements: capillary electrophoresis coupled with UV detection and mass spectrometry, and direct infusion mass spectrometry. | Journal of the American Society for Mass Spectrometry 20120701 |
| Determination of non-steroidal anti-inflammatory drugs in urine by the combination of stir membrane liquid-liquid-liquid microextraction and liquid chromatography. | Analytical and bioanalytical chemistry 20120701 |
| Enantiomeric resolution of ibuprofen and flurbiprofen in human plasma by SPE-chiral HPLC methods. | Combinatorial chemistry & high throughput screening 20120701 |
| NSAIDs induce apoptosis in nonproliferating ovarian cancer cells and inhibit tumor growth in vivo. | IUBMB life 20120701 |
| Chiral amines as reagents for HPLC-MS enantioseparation of chiral carboxylic acids. | Journal of separation science 20120701 |
| Flurbiprofen without a prescription for dysmenorrhoea: rejected by French Health Products Agency. | Prescrire international 20120701 |
| An examination of the thermodynamics of fusion, vaporization, and sublimation of (R,S)- and (R)-flurbiprofen by correlation gas chromatography. | Journal of pharmaceutical sciences 20120601 |
| Nanocomposite formation between alpha-glucosyl stevia and surfactant improves the dissolution profile of poorly water-soluble drug. | International journal of pharmaceutics 20120530 |
| Building a three-dimensional model of CYP2C9 inhibition using the Autocorrelator: an autonomous model generator. | Journal of chemical information and modeling 20120525 |
| Mechanism of action of hydrogen sulfide on cyclic AMP formation in rat retinal pigment epithelial cells. | Experimental eye research 20120501 |
| Takotsubo cardiomyopathy during ambulatory anesthesia for bladder hydrodistension therapy -A case report-. | Korean journal of anesthesiology 20120501 |
| Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. | Neurology 20120424 |
| Cytoprotective effect of nonsteroidal antiinflammatory drugs in rat brain slices subjected to reoxygenation after oxygen-glucose deprivation. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120411 |
| First and second generation γ-secretase modulators (GSMs) modulate amyloid-β (Aβ) peptide production through different mechanisms. | The Journal of biological chemistry 20120406 |
| miR-493 induction during carcinogenesis blocks metastatic settlement of colon cancer cells in liver. | The EMBO journal 20120404 |
| Glycosylation of human cyclooxygenase-2 (COX-2) decreases the efficacy of certain COX-2 inhibitors. | Pharmacological research 20120401 |
| Non-steroidal anti-inflammatory drugs and gastroprotection with proton pump inhibitors: a focus on ketoprofen/omeprazole. | Clinical drug investigation 20120401 |
| Effect of olive oil on transdermal penetration of flurbiprofen from topical gel as enhancer. | Pakistan journal of pharmaceutical sciences 20120401 |
| Seeing it through: translational validation of new medical imaging modalities. | Biomedical optics express 20120401 |
| Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms. | Journal of chemical information and modeling 20120326 |
| Tranexamic acid: a review of its use in the treatment of hyperfibrinolysis. | Drugs 20120326 |
| Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold. | Journal of medicinal chemistry 20120308 |
| Non-steroidal anti-inflammatory drugs and cognitive function: are prostaglandins at the heart of cognitive impairment in dementia and delirium? | Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20120301 |
| Novel surface-modified nanostructured lipid carriers with partially deacetylated water-soluble chitosan for efficient ocular delivery. | Journal of pharmaceutical sciences 20120301 |
| Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spot. | Clinical pharmacology and therapeutics 20120301 |
| Cyclodextrins as a chiral mobile phase additive in nano-liquid chromatography: comparison of reversed-phase silica monolithic and particulate capillary columns. | Analytical and bioanalytical chemistry 20120301 |
| Amino acid and vitamin supplementation improved health conditions in elderly participants. | Journal of clinical biochemistry and nutrition 20120301 |
| Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease. | The Cochrane database of systematic reviews 20120215 |
| The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein. | Brain research 20120203 |
| R-flurbiprofen, a novel nonsteroidal anti-inflammatory drug, decreases cell proliferation and induces apoptosis in pituitary adenoma cells in vitro. | Journal of neuro-oncology 20120201 |
| Improved and safe transcorneal delivery of flurbiprofen by NLC and NLC-based hydrogels. | Journal of pharmaceutical sciences 20120201 |
| Effects of solid carriers on the crystalline properties, dissolution and bioavailability of flurbiprofen in solid self-nanoemulsifying drug delivery system (solid SNEDDS). | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120201 |
| Immunodetection of cyclooxygenase-2 (COX-2) is restricted to tissue macrophages in normal rat liver and to recruited mononuclear phagocytes in liver injury and cholangiocarcinoma. | Histochemistry and cell biology 20120201 |
| A new methodology for simultaneous quantification of total-Aβ, Aβx-38, Aβx-40, and Aβx-42 by column-switching LC/MS/MS. | Analytical and bioanalytical chemistry 20120201 |
| Preemptive analgesic effects of flurbiprofen axetil in patients undergoing radical resection of esophageal carcinoma via the left thoracic approach. | Chinese medical journal 20120201 |
| Mechanisms of the cerebral vasodilator actions of isoflavonoids of Gegen on rat isolated basilar artery. | Journal of ethnopharmacology 20120106 |
| Impact of the counterion on the solubility and physicochemical properties of salts of carboxylic acid drugs. | Drug development and industrial pharmacy 20120101 |
| Marine sponge Hymeniacidon sp. amphilectane metabolites potently inhibit rat brain microglia thromboxane B2 generation. | Bioorganic & medicinal chemistry 20120101 |
| Aspirin: pharmacology and clinical applications. | Thrombosis 20120101 |
| Development of novel flurbiprofen-loaded solid self-microemulsifying drug delivery system using gelatin as solid carrier. | Journal of microencapsulation 20120101 |
| Presenilin is the molecular target of acidic γ-secretase modulators in living cells. | PloS one 20120101 |
| Influence of skin thickness on the in vitro permeabilities of drugs through Sprague-Dawley rat or Yucatan micropig skin. | Biological & pharmaceutical bulletin 20120101 |
| The use of an artificial skin model to study transdermal absorption of drugs in inflamed skin. | Biological & pharmaceutical bulletin 20120101 |
| Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology. | Frontiers in pharmacology 20120101 |
| Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models. | Journal of neuroinflammation 20120101 |
| Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trial. | BMJ open 20120101 |
| Dendrimers bind antioxidant polyphenols and cisplatin drug. | PloS one 20120101 |
| A randomised, two-period, cross-over, open-label study to evaluate the pharmacokinetic profiles of single doses of two different flurbiprofen 8.75-mg lozenges in healthy volunteers. | Pharmacology 20120101 |
| Therapeutic effect of CHF5074, a new γ-secretase modulator, in a mouse model of scrapie. | Prion 20120101 |
| Role of hydroxypropyl-β-cyclodextrin on freeze-dried and gamma-irradiated PLGA and PLGA-PEG diblock copolymer nanospheres for ophthalmic flurbiprofen delivery. | International journal of nanomedicine 20120101 |
| NO-NSAIDs. Part 3: nitric oxide-releasing prodrugs of non-steroidal anti-inflammatory drugs. | Chemical & pharmaceutical bulletin 20120101 |
| Flurbiprofen. | Profiles of drug substances, excipients, and related methodology 20120101 |
| Disruption of the serotonergic system after neonatal hypoxia-ischemia in a rodent model. | Neurology research international 20120101 |
| Laboratory monitoring of patients treated with antihypertensive drugs and newly exposed to non steroidal anti-inflammatory drugs: a cohort study. | PloS one 20120101 |
| Detection of herplex simplex virus-1 and -2 in cardiac myxomas. | Journal of biomedicine & biotechnology 20120101 |
| Cyclodextrin-containing polymers: versatile platforms of drug delivery materials. | Journal of drug delivery 20120101 |
| Chemically modified tetracyclines: Novel therapeutic agents in the management of chronic periodontitis. | Indian journal of pharmacology 20120101 |
| Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| A new investigation for some steroidal derivatives as anti-Alzheimer agents. | International journal of biological macromolecules 20120101 |
| Biogenic and synthetic polyamines bind cationic dendrimers. | PloS one 20120101 |
| A review: inflammatory process in Alzheimer's disease, role of cytokines. | TheScientificWorldJournal 20120101 |
| Comparative QSAR analysis of cyclo-oxygenase2 inhibiting drugs. | Bioinformation 20120101 |
| Update on twice-daily bromfenac sodium sesquihydrate to treat postoperative ocular inflammation following cataract extraction. | Clinical ophthalmology (Auckland, N.Z.) 20120101 |
| Design of cationic nanostructured heterolipid matrices for ocular delivery of methazolamide. | International journal of nanomedicine 20120101 |
| Drug Eruptions: An 8-year Study Including 106 Inpatients at a Dermatology Clinic in Turkey. | Indian journal of dermatology 20120101 |
| γ-Secretase modulator in Alzheimer's disease: shifting the end. | Journal of Alzheimer's disease : JAD 20120101 |
| Flurbiprofen, a cyclooxygenase inhibitor, protects mice from hepatic ischemia/reperfusion injury by inhibiting GSK-3β signaling and mitochondrial permeability transition. | Molecular medicine (Cambridge, Mass.) 20120101 |
| Biocatalytic synthesis of flavones and hydroxyl-small molecules by recombinant Escherichia coli cells expressing the cyanobacterial CYP110E1 gene. | Microbial cell factories 20120101 |
| Equilibrium and release properties of aqueous dispersions of non-steroidal anti-inflammatory drugs complexed with polyelectrolyte eudragit e 100. | Scientia pharmaceutica 20120101 |
| Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. | PloS one 20120101 |
| Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy. | The Journal of international medical research 20120101 |
| [Development of novel methods for preparing chiral non-steroidal anti-inflammatory drugs (NSAIDs) by asymmetric esterification]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101 |
| Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen. | Biochemical pharmacology 20111201 |
| Stereoselective inhibitory effect of flurbiprofen, ibuprofen and naproxen on human organic anion transporters hOAT1 and hOAT3. | Biopharmaceutics & drug disposition 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| [Effect of continuous intravenous infusion of flurbiprofen axetil and tramadol hydrochloride for postoperative pain management of laparoscopic colectomy]. | Masui. The Japanese journal of anesthesiology 20111201 |
| Impact and Therapeutic Potential of PPARs in Alzheimer's Disease. | Current neuropharmacology 20111201 |
| [Gamma-secretase inhibitors and modulators]. | Nihon rinsho. Japanese journal of clinical medicine 20111201 |
| NSAID-based γ-secretase modulators do not bind to the amyloid-β polypeptide. | Biochemistry 20111129 |
| Comparison of solid self-microemulsifying drug delivery system (solid SMEDDS) prepared with hydrophilic and hydrophobic solid carrier. | International journal of pharmaceutics 20111128 |
| Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein. | The Journal of biological chemistry 20111118 |
| Naproxen-induced fixed drug eruption: a case report. | Human & experimental toxicology 20111101 |
| Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs). | Prostaglandins & other lipid mediators 20111101 |
| The structure of NS-398 bound to cyclooxygenase-2. | Journal of structural biology 20111101 |
| Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys. | The Journal of pharmacology and experimental therapeutics 20111101 |
| (R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. | Nature chemical biology 20111101 |
| Multiple applications of flurbiprofen and chlorhexidine chips in patients with chronic periodontitis: a randomized, double blind, parallel, 2-arms clinical trial. | Journal of clinical periodontology 20111101 |
| Some pharmaceutical and inclusion properties of 2-hydroxybutyl-β-cyclodextrin derivative. | International journal of pharmaceutics 20111031 |
| [Effect of flurbiprofen combined different concentrations of ropivacaine local infiltration on postoperative analgesia after laparoscopic cholecystectomy]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20111018 |
| Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling pathways. | Chemical reviews 20111012 |
| Flurbiprofen axetil enhances analgesic effect of fentanyl associated with increase in β-endorphin levels. | Journal of anesthesia 20111001 |
| Effect of flurbiprofen, metoclopramide and droperidol for nausea and emesis during cesarean section under spinal anesthesia. | Journal of anesthesia 20111001 |
| Notch post-translationally regulates β-catenin protein in stem and progenitor cells. | Nature cell biology 20111001 |
| Enantioseparation of organic acids of pharmaceutical interest using eremomycin as a chiral selector. | Electrophoresis 20111001 |
| The γ-secretase modulator CHF5074 reduces the accumulation of native hyperphosphorylated tau in a transgenic mouse model of Alzheimer's disease. | Journal of molecular neuroscience : MN 20110901 |
| A dual acting compound releasing nitric oxide (NO) and ibuprofen, NCX 320, shows significant therapeutic effects in a mouse model of muscular dystrophy. | Pharmacological research 20110901 |
| Aggravation by paroxetine, a selective serotonin reuptake inhibitor, of antral lesions generated by nonsteroidal anti-inflammatory drugs in rats. | The Journal of pharmacology and experimental therapeutics 20110901 |
| Chiral separation of flurbiprofen enantiomers by preparative and simulated moving bed chromatography. | Chirality 20110901 |
| NSAID-derived γ-secretase modulation requires an acidic moiety on the carbazole scaffold. | Bioorganic & medicinal chemistry 20110815 |
| Lack of enantiomeric influence on the brain cytoprotective effect of ibuprofen and flurbiprofen. | Naunyn-Schmiedeberg's archives of pharmacology 20110801 |
| Flurbiprofen axetil, nasal polyps, and status asthmaticus: an unusual case report. | The Journal of asthma : official journal of the Association for the Care of Asthma 20110801 |
| Switching the microglial harmful phenotype promotes lifelong restoration of subtantia nigra dopaminergic neurons from inflammatory neurodegeneration in aged mice. | Rejuvenation research 20110801 |
| Structure and dynamics of the membrane-bound cytochrome P450 2C9. | PLoS computational biology 20110801 |
| The elements of human cyclin D1 promoter and regulation involved. | Clinical epigenetics 20110801 |
| Flurbiprofen encapsulation using pluronic triblock copolymers. | Langmuir : the ACS journal of surfaces and colloids 20110705 |
| Efficacy of the lidocaine/flurbiprofen axetil combination for reducing pain during the injection of propofol. | Minerva anestesiologica 20110701 |
| Novel NSAIDs ophthalmic formulation: flurbiprofen axetil emulsion with low irritancy and improved anti-inflammation effect. | International journal of pharmaceutics 20110630 |
| The Akt/GSK-3β pathway mediates flurbiprofen-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rats. | Biochemical and biophysical research communications 20110617 |
| Interaction between drug loaded polyaspartamide-polylactide-polysorbate based micelles and cell membrane models: a calorimetric study. | Molecular pharmaceutics 20110606 |
| Multivariate optimization of formulation variables influencing flurbiprofen proniosomes characteristics. | Journal of pharmaceutical sciences 20110601 |
| Anesthetic management of a patient with narcolepsy. | Journal of anesthesia 20110601 |
| Evaluation of four drugs for inhibition of paracentesis-induced blood-aqueous humor barrier breakdown in cats. | American journal of veterinary research 20110601 |
| Plasma asymmetric dimethylarginine predicts restenosis after coronary angioplasty. | Archives of medical science : AMS 20110601 |
| Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol. | Chemico-biological interactions 20110530 |
| Drug metabolism in hemorrhagic shock: pharmacokinetics of selective markers of cytochrome-P450 2C9, 2D6, and 3A4 enzyme activities in a porcine model. | The Journal of surgical research 20110515 |
| The neuroprotective effects of NMDAR antagonist, ifenprodil and ASIC1a inhibitor, flurbiprofen on post-ischemic cerebral injury. | Brain research 20110510 |
| Synthesis of α-aryl nitriles through palladium-catalyzed decarboxylative coupling of cyanoacetate salts with aryl halides and triflates. | Angewandte Chemie (International ed. in English) 20110502 |
| R-flurbiprofen improves axonal transport in the Tg2576 mouse model of Alzheimer's disease as determined by MEMRI. | Magnetic resonance in medicine 20110501 |
| Design and evaluation of ocusert for controlled delivery of flurbiprofen sodium. | Current eye research 20110501 |
| Combinations of protein-chemical complex structures reveal new targets for established drugs. | PLoS computational biology 20110501 |
| Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates. | Journal of medicinal chemistry 20110414 |
| The butterfly effect: a physical phenomenon of hypromellose matrices during dissolution and the factors affecting its occurrence. | International journal of pharmaceutics 20110315 |
| Supercritical fluid-assisted preparation of imprinted contact lenses for drug delivery. | Acta biomaterialia 20110301 |
| Effect of topical 0.03% flurbiprofen and 0.005% latanoprost, alone and in combination, on normal canine eyes. | Veterinary ophthalmology 20110301 |
| Enhanced solubility and bioavailability of flurbiprofen by cycloamylose. | Archives of pharmacal research 20110301 |
| A competition assay to identify amyloidogenesis inhibitors by monitoring the fluorescence emitted by the covalent attachment of a stilbene derivative to transthyretin. | Bioorganic & medicinal chemistry 20110215 |
| Cannabinoid system and cyclooxygenases inhibitors. | Journal of medicine and life 20110215 |
| Effect of process parameters on nanoemulsion droplet size and distribution in SPG membrane emulsification. | International journal of pharmaceutics 20110214 |
| A UPLC-MS/MS assay of the 'Pittsburgh cocktail': six CYP probe-drug/metabolites from human plasma and urine using stable isotope dilution. | The Analyst 20110207 |
| ASAS recommendations for collecting, analysing and reporting NSAID intake in clinical trials/epidemiological studies in axial spondyloarthritis. | Annals of the rheumatic diseases 20110201 |
| Wormlike micellar aggregates of saponins from Ilex paraguariensis A. St. Hil. (mate): a characterisation by cryo-TEM, rheology, light scattering and small-angle neutron scattering. | Journal of pharmaceutical sciences 20110201 |
| Determination of pharmacokinetics of flurbiprofen in Pakistani population using modified HPLC method. | Journal of chromatographic science 20110201 |
| Optimizing flurbiprofen-loaded NLC by central composite factorial design for ocular delivery. | Nanotechnology 20110128 |
| Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite. | Journal of pharmaceutical and biomedical analysis 20110125 |
| Nanostructured lipid carrier (NLC) coated with Chitosan Oligosaccharides and its potential use in ocular drug delivery system. | International journal of pharmaceutics 20110117 |
| Optimization of isocratic supercritical fluid chromatography for enantiomer separation. | Journal of chromatography. A 20110107 |
| Potential use of nanostructured lipid carriers for topical delivery of flurbiprofen. | Journal of pharmaceutical sciences 20110101 |
| Structural evaluation of crystalline ternary γ-cyclodextrin complex. | Journal of pharmaceutical sciences 20110101 |
| Physicochemical characterization and in vivo evaluation of flurbiprofen-loaded solid dispersion without crystalline change. | Drug delivery 20110101 |
| Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20110101 |
| Acrylic acid-methyl methacrylate (2.5:7.5/2:8) enteric copolymer for colon targeted drug delivery. | Journal of materials science. Materials in medicine 20110101 |
| Transgenic AD model mice, effects of potential anti-AD treatments on inflammation, and pathology. | Journal of Alzheimer's disease : JAD 20110101 |
| Use of non-steroidal anti-inflammatory drugs and prostate cancer risk: a population-based nested case-control study. | PloS one 20110101 |
| Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation. | Molecular neurodegeneration 20110101 |
| The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice. | Journal of Alzheimer's disease : JAD 20110101 |
| Newly identified CYP2C93 is a functional enzyme in rhesus monkey, but not in cynomolgus monkey. | PloS one 20110101 |
| IL-1β stimulates COX-2 dependent PGE₂ synthesis and CGRP release in rat trigeminal ganglia cells. | PloS one 20110101 |
| Transfer kinetics from colloidal drug carriers and liposomes to biomembrane models: DSC studies. | Journal of pharmacy & bioallied sciences 20110101 |
| Mucoadhesive drug delivery systems. | Journal of pharmacy & bioallied sciences 20110101 |
| Effects of flurbiprofen on CRP, TNF-α, IL-6, and postoperative pain of thoracotomy. | International journal of medical sciences 20110101 |
| Variation assessment for in vitro permeabilities through Yucatan micropig skin. | Biological & pharmaceutical bulletin 20110101 |
| Investigational drugs for the treatment of AD: what can we learn from negative trials? | Alzheimer's research & therapy 20110101 |
| Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes. | Journal of translational medicine 20110101 |
| Management of Intraoperative Miosis during Pediatric Cataract Surgery using Healon 5. | Middle East African journal of ophthalmology 20110101 |
| Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer's disease. | Molecular neurodegeneration 20110101 |
| Berberine inhibits human hepatoma cell invasion without cytotoxicity in healthy hepatocytes. | PloS one 20110101 |
| Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
| Usefulness of rat skin as a substitute for human skin in the in vitro skin permeation study. | Experimental animals 20110101 |
| Formulation and pharmacokinetic evaluation of a paclitaxel nanosuspension for intravenous delivery. | International journal of nanomedicine 20110101 |
| Biocompatibility and biodegradation studies of subconjunctival implants in rabbit eyes. | PloS one 20110101 |
| Lack of preemptive analgesia by intravenous flurbiprofen in thyroid gland surgery: a randomized, double-blind and placebo-controlled clinical trial. | International journal of medical sciences 20110101 |
| Apoptosis induced by piroxicam plus cisplatin combined treatment is triggered by p21 in mesothelioma. | PloS one 20110101 |
| Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy. | PloS one 20110101 |
| Characterization of a novel and spontaneous mouse model of inflammatory arthritis. | Arthritis research & therapy 20110101 |
| Transumbilical laparo-endoscopic single site surgery for adrenal cortical adenoma inducing primary aldosteronism: initial experience. | BMC research notes 20110101 |
| Dissolution behavior of β-cyclodextrin molecular inclusion complexes of aceclofenac. | Journal of pharmacy & bioallied sciences 20110101 |
| Anti-Aβ drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease. | PloS one 20110101 |
| Functional evaluation of genetic and environmental regulators of p450 mRNA levels. | PloS one 20110101 |
| Minocycline and doxycycline therapy in community patients with rheumatoid arthritis: prescribing patterns, patient-level determinants of use, and patient-reported side effects. | Arthritis research & therapy 20110101 |
| The effect of ketoprofen in chronic periodontitis: A clinical double-blind study. | Journal of Indian Society of Periodontology 20110101 |
| In situ formation of nanocrystals from a self-microemulsifying drug delivery system to enhance oral bioavailability of fenofibrate. | International journal of nanomedicine 20110101 |
| Anti-UVC irradiation and metal chelation properties of 6-benzoyl-5,7-dihydroxy-4-phenyl-chromen-2-one: an implications for anti-cataract agent. | International journal of molecular sciences 20110101 |
| Interacting with γ-secretase for treating Alzheimer's disease: from inhibition to modulation. | Current medicinal chemistry 20110101 |
| A systematic review of the effects of sedatives and anesthetics in patients with obstructive sleep apnea. | Journal of anaesthesiology, clinical pharmacology 20110101 |
| New surface-modified solid lipid nanoparticles using N-glutaryl phosphatidylethanolamine as the outer shell. | International journal of nanomedicine 20110101 |
| Development and evaluation of mucoadhesive buccal patches of flurbiprofen. | Acta poloniae pharmaceutica 20110101 |
| Different cellular effects of four anti-inflammatory eye drops on human corneal epithelial cells: independent in active components. | Molecular vision 20110101 |
| A simple high-performance liquid chromatographic practical approach for determination of flurbiprofen. | Journal of advanced pharmaceutical technology & research 20110101 |
| Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives. | Pharmacognosy reviews 20110101 |
| Preparation of Fluconazole β-Cyclodextrin Complex Ocuserts: In Vitro and In Vivo Evaluation. | ISRN pharmaceutics 20110101 |
| Enhance transdermal delivery of flurbiprofen via microemulsions: Effects of different types of surfactants and cosurfactants. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101 |
| Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives. | Chemical research in toxicology 20101220 |
| Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC. | Colloids and surfaces. B, Biointerfaces 20101201 |
| Neuroprotective effect of flurbiprofen in focal cerebral ischemia: the possible role of ASIC1a. | Neuropharmacology 20101201 |
| Life extension by diet restriction and N-acetyl-L-cysteine in genetically heterogeneous mice. | The journals of gerontology. Series A, Biological sciences and medical sciences 20101201 |
| Observation of an unusual electronically distorted semiquinone radical of PCB metabolites in the active site of prostaglandin H synthase-2. | Chemosphere 20101201 |
| A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Evaluation of percutaneous permeation of flurbiprofen and ketoprofen after application of transdermal patches using a lateral sectioning approach in hairless rats. | Pharmaceutical development and technology 20101201 |
| A potential nitrergic mechanism of action for indomethacin, but not of other COX inhibitors: relevance to indomethacin-sensitive headaches. | The journal of headache and pain 20101201 |
| Differences in the in vitro antiplatelet effect of dexibuprofen, ibuprofen, and flurbiprofen in human blood. | Anesthesia and analgesia 20101201 |
| NSAID inhibition of prostate cancer cell migration is mediated by Nag-1 Induction via the p38 MAPK-p75(NTR) pathway. | Molecular cancer research : MCR 20101201 |
| Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method. | Healthcare informatics research 20101201 |
| Drug development for Alzheimer's disease: recent progress. | Experimental neurobiology 20101201 |
| Improved drug loading/release capacities of commercial contact lenses obtained by supercritical fluid assisted molecular imprinting methods. | Journal of controlled release : official journal of the Controlled Release Society 20101120 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Validation of individual quantitative methods for determination of cytochrome P450 probe substrates in human dried blood spots with HPLC-MS/MS. | Bioanalysis 20101101 |
| [Population pharmacokinetic modeling of flurbiprofen]. | Yao xue xue bao = Acta pharmaceutica Sinica 20101101 |
| Does stereochemistry influence transdermal permeation of flurbiprofen through the rat skin? | Archives of dermatological research 20101001 |
| Transglycosylated stevia and hesperidin as pharmaceutical excipients: dramatic improvement in drug dissolution and bioavailability. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20101001 |
| Topical diclofenac epolamine patch 1.3% for treatment of acute pain caused by soft tissue injury. | International journal of clinical practice 20101001 |
| Nepafenac-assisted mydriasis in a rabbit model. | Journal of cataract and refractive surgery 20101001 |
| Are we prepared to deal with the Alzheimer's disease pandemic? | Clinical pharmacology and therapeutics 20101001 |
| Plasma and cerebrospinal fluid pharmacokinetics of flurbiprofen in children. | British journal of clinical pharmacology 20101001 |
| Effect of autogenous cortical bone grafting in conjunction with guided tissue regeneration in the treatment of intraosseous periodontal defects. | European journal of dentistry 20101001 |
| Acrylic acid-methyl methacrylate copolymer for oral prolonged drug release. | Journal of materials science. Materials in medicine 20100901 |
| Comparison of cyclooxygenase-1 crystal structures: cross-talk between monomers comprising cyclooxygenase-1 homodimers. | Biochemistry 20100824 |
| Small scale screening to determine the ability of different polymers to inhibit drug crystallization upon rapid solvent evaporation. | Molecular pharmaceutics 20100802 |
| Role of COX-2 in nonsteroidal anti-inflammatory drug enteropathy in rodents. | Scandinavian journal of gastroenterology 20100801 |
| Novel vehicle based on cubosomes for ophthalmic delivery of flurbiprofen with low irritancy and high bioavailability. | Acta pharmacologica Sinica 20100801 |
| Trypanosoma vivax infections: pushing ahead with mouse models for the study of Nagana. I. Parasitological, hematological and pathological parameters. | PLoS neglected tropical diseases 20100801 |
| [Progress in the development of anti-amyloid drugs for treatment of Alzheimer's disease.]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100701 |
| Enhancement of dissolution and bioavailability of flurbiprofen by low molecular weight chitosans. | Die Pharmazie 20100701 |
| [Drug therapy for Alzheimer's disease]. | Brain and nerve = Shinkei kenkyu no shinpo 20100701 |
| Improvement of dissolution and absorption properties of poorly water-soluble drug by preparing spray-dried powders with alpha-glucosyl hesperidin. | International journal of pharmaceutics 20100615 |
| Direct enantioselective HPLC monitoring of lipase-catalyzed kinetic resolution of flurbiprofen. | Chirality 20100601 |
| R-flurbiprofen suppresses distal nonmucin-producing colorectal tumors in azoxymethane-treated rats, without suppressing eicosanoid production. | American journal of physiology. Gastrointestinal and liver physiology 20100601 |
| Analgesic effect of parecoxib and flurbiprofen axetil for patients undergoing laparoscopic cholecystectomy and their influences on platelet aggregation. | Chinese medical journal 20100601 |
| Effect of centchroman coadministration on the pharmacokinetics of metformin in rats. | Indian journal of pharmacology 20100601 |
| Use of a robust dehydrogenase from an archael hyperthermophile in asymmetric catalysis-dynamic reductive kinetic resolution entry into (S)-profens. | Journal of the American Chemical Society 20100505 |
| Encapsulation and characterization of controlled release flurbiprofen loaded microspheres using beeswax as an encapsulating agent. | Journal of materials science. Materials in medicine 20100501 |
| Site of metabolism prediction on cytochrome P450 2C9: a knowledge-based docking approach. | Journal of computer-aided molecular design 20100501 |
| Role of hydrogen sulfide production in inhibitory action of L-cysteine on isolated porcine irides. | Current eye research 20100501 |
| Simultaneous dissolution of naproxen and flurbiprofen from a novel ternary gamma-cyclodextrin complex. | Chemical & pharmaceutical bulletin 20100501 |
| Confirmatory analysis of non-steroidal anti-inflammatory drugs in bovine milk by high-performance liquid chromatography with fluorescence detection. | Journal of chromatography. A 20100423 |
| Comparison of randomized treatments for late whiplash. | Neurology 20100413 |
| Effect of counter-ions and penetration enhancers on the skin permeation of flurbiprofen. | Journal of pharmaceutical sciences 20100401 |
| Disease-modifying drug fails in Alzheimer's study. | The Harvard mental health letter 20100401 |
| [The effect of flurbiprofen axetil on laparoscopic cholecystectomy]. | Zhonghua yi xue za zhi 20100323 |
| Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs. | Pflugers Archiv : European journal of physiology 20100301 |
| Tarenflurbil for Alzheimer's disease: a 'shot on goal' that missed. | The Lancet. Neurology 20100301 |
| Green hydrophilic interaction chromatography using ethanol-water-carbon dioxide mixtures. | Journal of separation science 20100301 |
| Comparative bioavailability and pharmacokinetics of investigational enteric- and film-coated formulations of flurbiprofen 100-mg tablets: a single-dose, randomized, open-label, two-period, two-way crossover study in healthy Pakistani male volunteers. | Clinical therapeutics 20100301 |
| Monocarboxylate transport in human corneal epithelium and cell lines. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100219 |
| COX-2 specific inhibitors enhance the cytotoxic effects of pemetrexed in mesothelioma cell lines. | Lung cancer (Amsterdam, Netherlands) 20100201 |
| R-flurbiprofen reverses multidrug resistance, proliferation and metastasis in gastric cancer cells by p75(NTR) induction. | Molecular pharmaceutics 20100201 |
| The disposition of free and niosomally encapsulated Rac-flurbiprofen in dairy bovines. | Journal of veterinary pharmacology and therapeutics 20100201 |
| Use of a mydriatic cocktail with a wick for preoperative mydriasis in cataract surgery: a prospective randomised controlled trial. | Eye (London, England) 20100101 |
| Release of PLGA-encapsulated dexamethasone from microsphere loaded porous surfaces. | Journal of materials science. Materials in medicine 20100101 |
| Eltrombopag, an oral thrombopoietin receptor agonist, has no impact on the pharmacokinetic profile of probe drugs for cytochrome P450 isoenzymes CYP3A4, CYP1A2, CYP2C9 and CYP2C19 in healthy men: a cocktail analysis. | European journal of clinical pharmacology 20100101 |
| Bovine beta-lactoglobulin acts as an acid-resistant drug carrier by exploiting its diverse binding regions. | Biological chemistry 20100101 |
| Current approach in diagnosis and management of anterior uveitis. | Indian journal of ophthalmology 20100101 |
| Caldesmon regulates the motility of vascular smooth muscle cells by modulating the actin cytoskeleton stability. | Journal of biomedical science 20100101 |
| Kinin B1 receptors contributes to acute pain following minor surgery in humans. | Molecular pain 20100101 |
| CHF5074, a novel gamma-secretase modulator, restores hippocampal neurogenesis potential and reverses contextual memory deficit in a transgenic mouse model of Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20100101 |
| Enhanced oral bioavailability of flurbiprofen by combined use of micelle solution and inclusion compound. | Archives of pharmacal research 20100101 |
| Enhanced oral bioavailability of flurbiprofen by combined use of micelle solution and inclusion compound. | Archives of pharmacal research 20100101 |
| Sumatriptan-naproxen fixed combination for acute treatment of migraine: a critical appraisal. | Drug design, development and therapy 20100101 |
| Immediate hypersensitivity reaction to a single oral dose of flurbiprofen. | Journal of postgraduate medicine 20100101 |
| Optimal identification of semi-rigid domains in macromolecules from molecular dynamics simulation. | PloS one 20100101 |
| R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids. | PloS one 20100101 |
| Explaining the atypical reaction profiles of heme enzymes with a novel mechanistic hypothesis and kinetic treatment. | PloS one 20100101 |
| Presenilin/gamma-Secretase and Inflammation. | Frontiers in aging neuroscience 20100101 |
| NSAIDs: How they Work and their Prospects as Therapeutics in Alzheimer's Disease. | Frontiers in aging neuroscience 20100101 |
| The pharmacokinetic profile of a novel fixed-dose combination tablet of ibuprofen and paracetamol. | BMC clinical pharmacology 20100101 |
| Influence of cyclodextrin complexation with NSAIDs on NSAID/cold stress-induced gastric ulceration in rats. | International journal of medical sciences 20100101 |
| The Nuclear Receptor PPARgamma as a Therapeutic Target for Cerebrovascular and Brain Dysfunction in Alzheimer's Disease. | Frontiers in aging neuroscience 20100101 |
| Are NSAIDs useful to treat Alzheimer's disease or mild cognitive impairment? | Frontiers in aging neuroscience 20100101 |
| Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma. | Respiratory research 20100101 |
| Comparison of cytochrome P450 3A enzymes in cynomolgus monkeys and humans. | Drug metabolism and pharmacokinetics 20100101 |
| Single dose dipyrone for acute postoperative pain. | The Cochrane database of systematic reviews 20100101 |
| Antidiarrhoeal Activity of the Alcoholic Extract of the Leaves of Butea frondosa Koen. Ex Roxb. | Indian journal of pharmaceutical sciences 20100101 |
| Brain amyloid β protein and memory disruption in Alzheimer's disease. | Neuropsychiatric disease and treatment 20100101 |
| Flavonoids diosmetin and hesperetin are potent inhibitors of cytochrome P450 2C9-mediated drug metabolism in vitro. | Drug metabolism and pharmacokinetics 20100101 |
| NSAIDs may protect against age-related brain atrophy. | Frontiers in aging neuroscience 20100101 |
| Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivatives. | Journal of Alzheimer's disease : JAD 20100101 |
| Cataract surgery under topical anesthesia using 2% lignocaine jelly and intracameral lignocaine: is manual small incision cataract surgery comparable to clear corneal phacoemulsification? | Indian journal of ophthalmology 20100101 |
| Materials for pharmaceutical dosage forms: molecular pharmaceutics and controlled release drug delivery aspects. | International journal of molecular sciences 20100101 |
| Cytochrome P450 reductase: a harbinger of diffusible reduced oxygen species. | PloS one 20100101 |
| Non-contraceptive applications of the levonorgestrel intrauterine system. | International journal of women's health 20100101 |
| Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. | Journal of neuroinflammation 20100101 |
| Microencapsulation: an acclaimed novel drug-delivery system for NSAIDs in arthritis. | Critical reviews in therapeutic drug carrier systems 20100101 |
| Pharmacophore elucidation and molecular docking studies on 5-phenyl-1-(3-pyridyl)-1h-1,2,4-triazole-3-carboxylic acid derivatives as COX-2 inhibitors. | Scientia pharmaceutica 20100101 |
| Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease. | Alzheimer's research & therapy 20100101 |
| Topical nonsteroidal anti-inflammatory drugs for the treatment of pain due to soft tissue injury: diclofenac epolamine topical patch. | Journal of pain research 20100101 |
| The effect of flurbiprofen as prophylactic analgesic before hysterosalpingography. | The Journal of international medical research 20100101 |
| [Ion-sensitive nanoemulsion-in situ gel system for ophthalmic delivery of flurbiprofen axetil]. | Yao xue xue bao = Acta pharmaceutica Sinica 20100101 |
| The link between periodontal disease and cardiovascular disease: How far we have come in last two decades ? | Journal of Indian Society of Periodontology 20100101 |
| Risk of Upper Gastrointestinal Bleeding in a Cohort of New Users of Low-Dose ASA for Secondary Prevention of Cardiovascular Outcomes. | Frontiers in pharmacology 20100101 |
| Effect of intensive non-surgical treatment on the level of serum inflammatory markers in advanced periodontitis. | Journal of dentistry (Tehran, Iran) 20100101 |
| Therapeutic and cosmeceutical potential of ethosomes: An overview. | Journal of advanced pharmaceutical technology & research 20100101 |
| Microsponges: A novel strategy for drug delivery system. | Journal of advanced pharmaceutical technology & research 20100101 |
| Niosome: A future of targeted drug delivery systems. | Journal of advanced pharmaceutical technology & research 20100101 |
| Adverse drug effects in hospitalized elderly: data from the healthcare cost and utilization project. | Clinical pharmacology : advances and applications 20100101 |
| Microencapsulation of flavors in carnauba wax. | Sensors (Basel, Switzerland) 20100101 |
| Pluronic lecithin organogel as a topical drug delivery system. | Drug delivery 20100101 |
| Cyclooxygenase competitive inhibitors alter tyrosyl radical dynamics in prostaglandin H synthase-2. | Biochemistry 20091222 |
| Suzuki-Miyaura coupling of aryl carbamates, carbonates, and sulfamates. | Journal of the American Chemical Society 20091216 |
| Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial. | JAMA 20091216 |
| Late-life dementias: does this unyielding global challenge require a broader view? | JAMA 20091216 |
| Enantioseparation of flurbiprofen on amylose-derived chiral stationary phase by supercritical fluid chromatography. | Journal of chromatography. A 20091211 |
| Role of prostanoid production and receptors in the regulation of retinal endogenous amino acid neurotransmitters by 8-isoprostaglandin E2, ex vivo. | Neurochemical research 20091201 |
| Possible involvement of microglia containing cyclooxygenase-1 in the accumulation of gonadotrophin-releasing hormone in the preoptic area in female rats. | Journal of neuroendocrinology 20091201 |
| Formulation and evaluation of natural gum-based sustained release matrix tablets of flurbiprofen using response surface methodology. | Drug development and industrial pharmacy 20091201 |
| New insights into the structural features and functional relevance of human cytochrome P450 2C9. Part II. | Current drug metabolism 20091201 |
| New insights into the structural features and functional relevance of human cytochrome P450 2C9. Part I. | Current drug metabolism 20091201 |
| An NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1. | Biochemistry 20091124 |
| Two pathways for cyclooxygenase-2 protein degradation in vivo. | The Journal of biological chemistry 20091106 |
| Differences in the interaction between aryl propionic acid derivatives and poly(vinylpyrrolidone) K30: A multi-methodological approach. | Journal of pharmaceutical sciences 20091101 |
| NO-flurbiprofen reduces amyloid-beta, is neuroprotective in cell culture, and enhances cognition in response to cholinergic blockade. | Journal of neurochemistry 20091101 |
| Selective modulation of amyloid-beta peptide degradation by flurbiprofen, fenofibrate, and related compounds regulates Abeta levels. | Journal of neurochemistry 20091101 |
| [Effects of preemptive analgesia with flurbiprofen on the blood sugar and interleukin-6 of patients after radical excision of breast cancer]. | Zhonghua yi xue za zhi 20091027 |
| Retinoid X receptor-alpha mediates (R )-flurbiprofen's effect on the levels of Alzheimer's beta-amyloid. | Journal of neurochemistry 20091001 |
| Theoretical characterization of substrate access/exit channels in the human cytochrome P450 3A4 enzyme: involvement of phenylalanine residues in the gating mechanism. | The journal of physical chemistry. B 20091001 |
| Improvement of dissolution property of poorly water-soluble drug by supercritical freeze granulation. | Chemical & pharmaceutical bulletin 20091001 |
| Allergen-induced airway inflammation and its therapeutic intervention. | Allergy, asthma & immunology research 20091001 |
| Tramadol and flurbiprofen depress the cytotoxicity of cisplatin via their effects on gap junctions. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090915 |
| Improvement of oral bioavailability of flurbiprofen from flurbiprofen/beta-cyclodextrin inclusion complex by action of cinnarizine. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090901 |
| Cloud point extraction with surfactant derivatization as an enrichment step prior to gas chromatographic or gas chromatography-mass spectrometric analysis. | Analytical chemistry 20090815 |
| Differential sensitivity and mechanism of inhibition of COX-2 oxygenation of arachidonic acid and 2-arachidonoylglycerol by ibuprofen and mefenamic acid. | Biochemistry 20090811 |
| Effect of polymer viscosity on physicochemical properties and ocular tolerance of FB-loaded PLGA nanospheres. | Colloids and surfaces. B, Biointerfaces 20090801 |
| CYP2D6-CYP2C9 protein-protein interactions and isoform-selective effects on substrate binding and catalysis. | Drug metabolism and disposition: the biological fate of chemicals 20090801 |
| Influence of prolonged exposure of a short half life non-steroidal anti-inflammatory drugs on gastrointestinal safety. | Inflammopharmacology 20090801 |
| Pharmacokinetic and bioequivalence comparison between orally disintegrating and conventional tablet formulations of flurbiprofen: a single-dose, randomized-sequence, open-label, two-period crossover study in healthy Chinese male volunteers. | Clinical therapeutics 20090801 |
| Buccal mucoadhesive tablets of flurbiprofen: Characterization and optimization. | Drug discoveries & therapeutics 20090801 |
| 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells. | Archives of biochemistry and biophysics 20090715 |
| Solubilization of flurbiprofen within non-ionic Tween 20 surfactant micelles: a 19F and 1H NMR study. | Physical chemistry chemical physics : PCCP 20090714 |
| pKa and solubility of drugs in water, ethanol, and 1-octanol. | The journal of physical chemistry. B 20090702 |
| Spectroscopic and DFT studies of flurbiprofen as dimer and its Cu(II) and Hg(II) complexes. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090701 |
| Separation-oriented derivatization of native fluorescent compounds through fluorous labeling followed by liquid chromatography with fluorous-phase. | Analytical chemistry 20090615 |
| Macrocyclic antibiotics as chiral selectors in the design of enantioselective, potentiometric membrane electrodes for the determination of S-flurbiprofen. | Analytical and bioanalytical chemistry 20090601 |
| The individual and combined effects of U50,488, and flurbiprofen axetil on visceral pain in conscious rats. | Anesthesia and analgesia 20090601 |
| [Prospective study on anesthesia for lumbar spine surgery--the effectiveness of the perioperative epidural anesthesia with buprenorphine]. | Masui. The Japanese journal of anesthesiology 20090601 |
| [Perioperative anesthetic management of a patient with multiple sclerosis]. | Masui. The Japanese journal of anesthesiology 20090601 |
| Mechanism-based treatments for Alzheimer's disease. | Dialogues in clinical neuroscience 20090601 |
| [Effect of preemptive analgesia with flurbiprofen axetil on patient-controlled intravenous analgesia with tramadol in patients undergoing postburn plastic surgery]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090601 |
| Translational medicine lessons from flurizan's failure in Alzheimer's disease (AD) trial: Implication for future drug discovery and development for AD. | Clinical and translational science 20090601 |
| Clonidine in paediatrics - a review. | Indian journal of anaesthesia 20090601 |
| In situ transient spectroscopy for the study of glucuronidase activity within serum albumin. | The journal of physical chemistry. B 20090514 |
| Enantiomeric separation of acidic compounds by nano-liquid chromatography with methylated-beta-cyclodextrin as a mobile phase additive. | Journal of separation science 20090501 |
| Hypersensitivity myocarditis and hypersensitivity coronary syndrome (Kounis syndrome). | The American journal of emergency medicine 20090501 |
| Enantiorecognition of profens by capillary electrophoresis using a novel chiral selector eremomycin. | Journal of chromatography. A 20090424 |
| Prediction of the effects of genetic polymorphism on the pharmacokinetics of CYP2C9 substrates from in vitro data. | Pharmaceutical research 20090401 |
| What we have learned from the Myriad trials. | The journal of nutrition, health & aging 20090401 |
| Mosapride and postoperative ileus. | Diseases of the colon and rectum 20090401 |
| Pretreatment with flurbiprofen axetil, flurbiprofen axetil preceded by venous occlusion, and a mixture of flurbiprofen axetil and propofol in reducing pain on injection of propofol in adult Japanese surgical patients: a prospective, randomized, double-blind, placebo-controlled study. | Clinical therapeutics 20090401 |
| A randomized controlled study on effects of ibuprofen on cognitive progression of Alzheimer's disease. | Aging clinical and experimental research 20090401 |
| Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs. | Chemico-biological interactions 20090316 |
| Cyclomaltoheptaose mixed esters of anti-inflammatory drugs and short-chain fatty acids and study of their enzymatic hydrolysis in vitro. | Carbohydrate research 20090310 |
| Mechanism of CYP2C9 inhibition by flavones and flavonols. | Drug metabolism and disposition: the biological fate of chemicals 20090301 |
| CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease. | British journal of pharmacology 20090301 |
| [Postoperative analgesia with fentanyl combined with flurbiprofen axetil following gynecologic surgery for turnor]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090201 |
| [In vitro effects of a novel class of nitric oxide donating compounds on isolated human urinary bladder]. | Georgian medical news 20090201 |
| Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid. | Aging 20090201 |
| The nitrosylated flurbiprofen derivative HCT1026 inhibits cytokine-induced signalling through a novel mechanism of action. | European journal of pharmacology 20090114 |
| Myocarditis due to oral flurbiprofen use. | The American journal of emergency medicine 20090101 |
| Possibility of topical antioxidant treatment of cataracts: corneal penetration of pyruvate in humans. | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20090101 |
| Intravitreal toxicity of ketorolac tris salt and flurbiprofen. | Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20090101 |
| Recent developments in Alzheimer's disease therapeutics. | BMC medicine 20090101 |
| Adipic acid dihydrazide treated partially oxidized alginate beads for sustained oral delivery of flurbiprofen. | Pharmaceutical development and technology 20090101 |
| Lipid nanoparticles for transdermal delivery of flurbiprofen: formulation, in vitro, ex vivo and in vivo studies. | Lipids in health and disease 20090101 |
| Intravenous flurbiprofen axetil can increase analgesic effect in refractory cancer pain. | Journal of experimental & clinical cancer research : CR 20090101 |
| Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately? | The open neurology journal 20090101 |
| Clinical study on the bioequivalence of two tablet formulations of flurbiprofen. | European journal of drug metabolism and pharmacokinetics 20090101 |
| Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. | Current medicinal chemistry 20090101 |
| Why did tarenflurbil fail in Alzheimer's disease? | Journal of Alzheimer's disease : JAD 20090101 |
| Single dose oral flurbiprofen for acute postoperative pain in adults. | The Cochrane database of systematic reviews 20090101 |
| Pathogenesis of tendinopathies: inflammation or degeneration? | Arthritis research & therapy 20090101 |
| Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis. | PloS one 20090101 |
| Diclofenac prevents temporal increase of intraocular pressure after uneventful cataract surgery with longer operation time. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Treatment of cystoid macular edema with the new-generation NSAID nepafenac 0.1%. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Management of ocular inflammation and pain following cataract surgery: focus on bromfenac ophthalmic solution. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Inhibition of surgically induced miosis and prevention of postoperative macular edema with nepafenac. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Association between KCNJ6 (GIRK2) gene polymorphisms and postoperative analgesic requirements after major abdominal surgery. | PloS one 20090101 |
| Pharmacokinetics and tolerance study of intravitreal injection of dexamethasone-loaded nanoparticles in rabbits. | International journal of nanomedicine 20090101 |
| Drugs associated with more suicidal ideations are also associated with more suicide attempts. | PloS one 20090101 |
| Subpopulations of neurons in visual area v2 perform differentiation and integration operations in space and time. | Frontiers in systems neuroscience 20090101 |
| Amitriptyline for pain control in scleritis may help to avoid excessive steroid use in selected cases: a case report. | Cases journal 20090101 |
| Efficacy of epicutaneous Diractin (ketoprofen in Transfersome gel) for the treatment of pain related to eccentric muscle contractions. | Drug design, development and therapy 20090101 |
| Postoperative analgesic effect of preoperative intravenous flurbiprofen in arthroscopic rotator cuff repair. | Journal of anesthesia 20090101 |
| Allosteric modulation of PS1/gamma-secretase conformation correlates with amyloid beta(42/40) ratio. | PloS one 20090101 |
| Bioavailability of ibuprofen following oral administration of standard ibuprofen, sodium ibuprofen or ibuprofen acid incorporating poloxamer in healthy volunteers. | BMC clinical pharmacology 20090101 |
| Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial. | Arthritis research & therapy 20090101 |
| Identification of human UDP-glucuronosyltransferase isoforms responsible for the glucuronidation of glycyrrhetinic acid. | Drug metabolism and pharmacokinetics 20090101 |
| Topical delivery of flurbiprofen from pluronic lecithin organogel. | Indian journal of pharmaceutical sciences 20090101 |
| Solid lipid nanoparticles: a modern formulation approach in drug delivery system. | Indian journal of pharmaceutical sciences 20090101 |
| Stabilization of quinapril by incorporating hydrogen bonding interactions. | Indian journal of pharmaceutical sciences 20090101 |
| Safety, efficacy and patient acceptability of the contraceptive and non-contraceptive uses of the LNG-IUS. | International journal of women's health 20090101 |
| Etiology and treatment of the inflammatory causes of cystoid macular edema. | Journal of inflammation research 20090101 |
| Therapeutic time window of flurbiprofen axetil's neuroprotective effect in a rat model of transient focal cerebral ischemia. | Chinese medical journal 20081220 |
| 1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: synthesis and preliminary evaluation of biological properties. | European journal of medicinal chemistry 20081201 |
| PLGA nanospheres for the ocular delivery of flurbiprofen: drug release and interactions. | Journal of pharmaceutical sciences 20081201 |
| The HSA affinity of warfarin and flurbiprofen determined by fluorescence anisotropy measurements of camptothecin. | Bio Systems 20081201 |
| Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner. | Mechanisms of ageing and development 20081201 |
| Inhibitory action of hydrogen sulfide on muscarinic receptor-induced contraction of isolated porcine irides. | Experimental eye research 20081201 |
| Nanocomposites of 2-arylpropionic acid drugs based on Mg-Al layered double hydroxide for dissolution enhancement. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20081115 |
| Functional analysis of phenylalanine residues in the active site of cytochrome P450 2C9. | Biochemistry 20081111 |
| Photocrosslinkable starch-based polymers for ophthalmologic drug delivery. | International journal of biological macromolecules 20081101 |
| Tarenflurbil protection from cytotoxicity is associated with an upregulation of neurotrophins. | Journal of Alzheimer's disease : JAD 20081101 |
| The effects of etodolac, nimesulid and naproxen sodium on the frequency of sister chromatid exchange after enclused third molars surgery. | Yonsei medical journal 20081031 |
| Condensed bridgehead nitrogen heterocyclic system: synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid. | European journal of medicinal chemistry 20081001 |
| Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice. | Aging cell 20081001 |
| Safety and clinical responses in ankylosing spondylitis after three months of etanercept therapy. | Journal of Korean medical science 20081001 |
| Dihydrotanshinone, a lipophilic component of Salvia miltiorrhiza (danshen), relaxes rat coronary artery by inhibition of calcium channels. | Journal of ethnopharmacology 20080926 |
| Chiral ionic liquids for enantioseparation of pharmaceutical products by capillary electrophoresis. | Journal of chromatography. A 20080919 |
| Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative. | Journal of chromatography. A 20080919 |
| Determining binding sites of drugs on human serum albumin using FIA-QCM. | Biosensors & bioelectronics 20080915 |
| Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes. | International journal of pharmaceutics 20080901 |
| Improvement in bioavailability of transdermally applied flurbiprofen using tulsi (Ocimum sanctum) and turpentine oil. | Colloids and surfaces. B, Biointerfaces 20080901 |
| In vitro evaluation of proniosomes as a drug carrier for flurbiprofen. | AAPS PharmSciTech 20080901 |
| Improvement of dissolution property of poorly water-soluble drug by novel dry coating method using planetary ball mill. | Chemical & pharmaceutical bulletin 20080901 |
| Effect of pH and formulation variables on in vitro transcorneal permeability of flurbiprofen: a technical note. | AAPS PharmSciTech 20080901 |
| Determination of flurbiprofen enantiomers in plasma using a single-isomer amino cyclodextrin derivative in nonaqueous capillary electrophoresis. | Electrophoresis 20080901 |
| Alpha-methylprednisolone conjugated cyclodextrin polymer-based nanoparticles for rheumatoid arthritis therapy. | International journal of nanomedicine 20080901 |
| Ionic liquid-based dynamic liquid-phase microextraction: application to the determination of anti-inflammatory drugs in urine samples. | Journal of chromatography. A 20080815 |
| Present and prospective clinical therapeutic regimens for Alzheimer's disease. | Neuropsychiatric disease and treatment 20080801 |
| The effects of topical (gel) astemizole and terfenadine on wound healing. | Indian journal of pharmacology 20080801 |
| Substrate proton to heme distances in CYP2C9 allelic variants and alterations by the heterotropic activator, dapsone. | Archives of biochemistry and biophysics 20080715 |
| Characterization of the drug binding specificity of rat liver fatty acid binding protein. | Journal of medicinal chemistry 20080710 |
| Species differences in inhibition potential of nonsteroidal anti-inflammatory drugs against estradiol 3beta-glucuronidation between rats, dogs, and humans. | Journal of pharmaceutical sciences 20080701 |
| Method for comparing the structures of protein ligand-binding sites and application for predicting protein-drug interactions. | Proteins 20080701 |
| [Acute renal insufficiency after flurbiprofen treatment in a patient treated with angiotensin converting enzyme inhibitor]. | La Revue de medecine interne 20080701 |
| Differential genotype dependent inhibition of CYP2C9 in humans. | Drug metabolism and disposition: the biological fate of chemicals 20080701 |
| Addition of nitric oxide through nitric oxide-paracetamol enhances healing rat achilles tendon. | Clinical orthopaedics and related research 20080701 |
| Intravenous flurbiprofen axetil accelerates restoration of bowel function after colorectal surgery. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20080701 |
| Wet process-induced phase-transited drug delivery system: a means for achieving osmotic, controlled, and level A IVIVC for poorly water-soluble drug. | Drug development and industrial pharmacy 20080701 |
| Oral colon targeted delivery systems for treatment of inflammatory bowel diseases: synthesis, in vitro and in vivo assessment. | International journal of pharmaceutics 20080624 |
| Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
| Thermodynamic studies of Fenbufen, Diflunisal, and Flurbiprofen: sublimation, solution and solvation of biphenyl substituted drugs. | International journal of pharmaceutics 20080605 |
| Topical ocular delivery of NSAIDs. | The AAPS journal 20080601 |
| Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial. | The Lancet. Neurology 20080601 |
| Tarenflurbil: a shot on goal. | The Lancet. Neurology 20080601 |
| Cloud point extraction-HPLC method for determination and pharmacokinetic study of flurbiprofen in rat plasma after oral and transdermal administration. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080601 |
| The therapeutic effects of Rho-ROCK inhibitors on CNS disorders. | Therapeutics and clinical risk management 20080601 |
| Topical ophthalmic NSAIDs: a discussion with focus on nepafenac ophthalmic suspension. | Clinical ophthalmology (Auckland, N.Z.) 20080601 |
| Rheological and functional characterization of new antiinflammatory delivery systems designed for buccal administration. | International journal of pharmaceutics 20080522 |
| Preparation and characterization of flurbiprofen-loaded poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microspheres. | Journal of microencapsulation 20080501 |
| Optimizing delivery of flurbiprofen to the colon using a targeted prodrug approach. | The Journal of pharmacy and pharmacology 20080501 |
| Analysis of flurbiprofen, ketoprofen and etodolac enantiomers by pre-column derivatization RP-HPLC and application to drug-protein binding in human plasma. | Journal of pharmaceutical and biomedical analysis 20080414 |
| Impregnation of an intraocular lens for ophthalmic drug delivery. | Current drug delivery 20080401 |
| Osmotically regulated flow of flurbiprofen through in situ formed asymmetric membrane capsule. | Current drug delivery 20080401 |
| Investigation of nanostructured lipid carriers for transdermal delivery of flurbiprofen. | Drug development and industrial pharmacy 20080401 |
| [Application of flurbiprofen preemptive analgesia combined with intravenous propofol anesthesia in induced abortion]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080401 |
| Transient absorption spectroscopy for determining multiple site occupancy in drug-protein conjugates. A comparison between human and bovine serum albumins using flurbiprofen methyl ester as a probe. | The journal of physical chemistry. B 20080306 |
| Non-steroidal anti-inflammatory drugs have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro. | Neuropharmacology 20080301 |
| Assessment of drug release from oil depot formulations using an in vitro model -- potential applicability in accelerated release testing. | Drug development and industrial pharmacy 20080301 |
| Development of enteric coated flurbiprofen tablets using Opadry/Acryl-Eze system--a technical note. | AAPS PharmSciTech 20080301 |
| Taking the next steps in the treatment of Alzheimer's disease: disease-modifying agents. | CNS spectrums 20080301 |
| Prediction of metabolism by cytochrome P450 2C9: alignment and docking studies of a validated database of substrates. | Journal of medicinal chemistry 20080227 |
| A comparison of the effectiveness of selected non-steroidal anti-inflammatory drugs and their derivatives against cancer cells in vitro. | Cancer chemotherapy and pharmacology 20080201 |
| Celecoxib inhibits proliferation of retinal pigment epithelial and choroid-retinal endothelial cells by a cyclooxygenase-2-independent mechanism. | The Journal of pharmacology and experimental therapeutics 20080201 |
| Modulatory effect of chiral nonsteroidal anti-inflammatory drugs on apoptosis of human neutrophils. | Chirality 20080201 |
| Synthesis and pharmacological evaluation of pyrazoline derivatives as new anti-inflammatory and analgesic agents. | Bioorganic & medicinal chemistry letters 20080201 |
| Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment. | European journal of clinical pharmacology 20080201 |
| Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung. | Prostaglandins, leukotrienes, and essential fatty acids 20080201 |
| Comparison of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, parallel-group, placebo-controlled study. | Clinical therapeutics 20080201 |
| Celecoxib transiently inhibits cellular protein synthesis. | Biochemical pharmacology 20080115 |
| Mechanisms of the dilator action of cryptotanshinone on rat coronary artery. | European journal of pharmacology 20080114 |
| Prejunctional inhibitory effects of isoprostanes on dopaminergic neurotransmission in bovine retinae, in vitro. | Neurochemical research 20080101 |
| In vivo methods for the assessment of topical drug bioavailability. | Pharmaceutical research 20080101 |
| Flurbiprofen derivatives in Alzheimer's disease: synthesis, pharmacokinetic and biological assessment of lipoamino acid prodrugs. | Bioconjugate chemistry 20080101 |
| Dosage plan of a flurbiprofen injection product using inhibition of protein binding by lipid emulsion in rats. | The Journal of pharmacy and pharmacology 20080101 |
| [In-vitro evaluation of cinnarizine as a competing agent to beta-cyclodextrin inclusion complexes: effect of cinnarizine on the membrane permeation rate of progesterone from its beta-cyclodextrin inclusion complex]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080101 |
| Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas. | Cerebrospinal fluid research 20080101 |
| Formulation and evaluation of flurbiprofen microemulsion. | Current drug delivery 20080101 |
| Analgesic effect of percutaneously absorbed non-steroidal anti-inflammatory drugs: an experimental study in a rat acute inflammation model. | BMC musculoskeletal disorders 20080101 |
| Confirmatory identification of sixteen non-steroidal anti-inflammatory drug residues in raw milk by liquid chromatography coupled with ion trap mass spectrometry. | Rapid communications in mass spectrometry : RCM 20080101 |
| Transconjunctival orbital emphysema caused by compressed air injury: a case report. | Indian journal of ophthalmology 20080101 |
| Regulation of Glial Cell Functions by PPAR-gamma Natural and Synthetic Agonists. | PPAR research 20080101 |
| Straw blood cell count, growth, inhibition and comparison to apoptotic bodies. | BMC cell biology 20080101 |
| Molecular analysis of the effects of Piroxicam and Cisplatin on mesothelioma cells growth and viability. | Journal of translational medicine 20080101 |
| Interactions between APP secretases and inflammatory mediators. | Journal of neuroinflammation 20080101 |
| PPAR-gamma: Therapeutic Potential for Multiple Sclerosis. | PPAR research 20080101 |
| PPARs in Alzheimer's Disease. | PPAR research 20080101 |
| Mitochondrial Ca2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDs. | PloS one 20080101 |
| Efficacy of intraoperative vancomycin in irrigating solutions on aqueous contamination during phacoemulsification. | Indian journal of ophthalmology 20080101 |
| Acquired Brown's syndrome associated with preseptal cellulitis. | Strabismus 20080101 |
| Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein. | Molecular brain 20080101 |
| Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis. | Arthritis research & therapy 20080101 |
| Role of nitric oxide in the gastrointestinal tract. | Arthritis research & therapy 20080101 |
| Inflammaging as a prodrome to Alzheimer's disease. | Journal of neuroinflammation 20080101 |
| Cyclooxygenase inhibitors: a novel direction for Alzheimer's management. | Pharmacological reports : PR 20080101 |
| A role for non-antimicrobial actions of tetracyclines in combating oxidative stress in periodontal and metabolic diseases: a literature review. | The open dentistry journal 20080101 |
| Surgical results of triamcinolone assisted pars plana vitrectomy combined with phacoemulsification in diabetic patients. | The open ophthalmology journal 20080101 |
| Transcorneal permeation in a corneal device of non-steroidal anti-inflammatory drugs in drug delivery systems. | The open medicinal chemistry journal 20080101 |
| A Study on Improvement of Solubility of Rofecoxib and its effect on Permeation of Drug from Topical Formulations. | Indian journal of pharmaceutical sciences 20080101 |
| Diclofenac patches for postoperative shoulder pain. | International journal of shoulder surgery 20080101 |
| In situ formed phase transited drug delivery system of ketoprofen for achieving osmotic, controlled and level a in vitro in vivo correlation. | Indian journal of pharmaceutical sciences 20080101 |
| Pharmacological nature of nicotine-induced contraction in the rat basilar artery: involvement of arachidonic acid metabolites. | European journal of pharmacology 20071222 |
| Involvement of organic anion transport system in transdermal absorption of flurbiprofen. | Journal of controlled release : official journal of the Controlled Release Society 20071204 |
| 1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity. | The Journal of pharmacology and experimental therapeutics 20071201 |
| The p38 MAPK pathway mediates aryl propionic acid induced messenger rna stability of p75 NTR in prostate cancer cells. | Cancer research 20071201 |
| Preoperative flurbiprofen for pain prevention after tonsillectomy in adults. | Journal of clinical anesthesia 20071201 |
| Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions. | Current neuropharmacology 20071201 |
| Analgesic and anti-inflammatory effectiveness of nepafenac 0.1% for cataract surgery. | Clinical ophthalmology (Auckland, N.Z.) 20071201 |
| The thermodynamic dissociation constants of four non-steroidal anti-inflammatory drugs by the least-squares nonlinear regression of multiwavelength spectrophotometric pH-titration data. | Journal of pharmaceutical and biomedical analysis 20071130 |
| Flurbiprofen, a cyclooxygenase inhibitor, reduces the brain arachidonic acid signal in response to the cholinergic muscarinic agonist, arecoline, in awake rats. | Neurochemical research 20071101 |
| New form discovery for the analgesics flurbiprofen and sulindac facilitated by polymer-induced heteronucleation. | Journal of pharmaceutical sciences 20071101 |
| The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver. | Drug metabolism and disposition: the biological fate of chemicals 20071101 |
| [Management of antiplatelet therapy: a case report]. | Annales de cardiologie et d'angeiologie 20071101 |
| Analysis of skin disposition of flurbiprofen after topical application using dual agar gel discs-inserted rats. | Biological & pharmaceutical bulletin 20071101 |
| Relative non-steroidal anti-inflammatory drug (NSAID) antiproliferative activity is mediated through p21-induced G1 arrest and E2F inhibition. | Molecular carcinogenesis 20071001 |
| Beta-amyloid(1-42) induces a reduction in the parallel fiber responses of Purkinje cells: possible involvement of pro-inflammatory processes. | Experimental gerontology 20071001 |
| A validated method for the analysis of diltiazem in raw materials and pharmaceutical formulations by rp-HPLC. | Pakistan journal of pharmaceutical sciences 20071001 |
| Imaging the Abeta-related neurotoxicity of Alzheimer disease. | Archives of neurology 20071001 |
| [Effect of postoperative analgesia with flurbiprofen axetil and sufentanyl on metabolism of surgical patients with intestinal carcinoma]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20071001 |
| Osmotic delivery of flurbiprofen through controlled porosity asymmetric membrane capsule. | Drug development and industrial pharmacy 20071001 |
| [Is withdrawal of antiplatelet therapy necessary prior to skin cancer surgery?]. | Annales de dermatologie et de venereologie 20071001 |
| GCF MMP-8 levels in smokers and non-smokers with chronic periodontitis following scaling and root planing accompanied by systemic use of flurbiprofen. | Journal of periodontology 20071001 |
| Progress update: Pharmacological treatment of Alzheimer's disease. | Neuropsychiatric disease and treatment 20071001 |
| The amyloid beta ion channel hypothesis of Alzheimer's disease. | Neuropsychiatric disease and treatment 20071001 |
| Topical antiinflammatory activity of an innovative aqueous formulation of actichelated propolis vs two commercial propolis formulations. | Phytotherapy research : PTR 20070901 |
| Preparation and evaluation of biodegradable flubiprofen gelatin micro-spheres for intra-articular administration. | Journal of microencapsulation 20070901 |
| Mechanisms of the vasorelaxant effect of 1-hydroxy-2, 3, 5-trimethoxy-xanthone, isolated from a Tibetan herb, Halenia elliptica, on rat coronary artery. | Life sciences 20070901 |
| Asymmetric membrane capsule for osmotic delivery of flurbiprofen. | Acta pharmaceutica (Zagreb, Croatia) 20070901 |
| Effective virtual screening protocol for CYP2C9 ligands using a screening site constructed from flurbiprofen and S-warfarin pockets. | Journal of computer-aided molecular design 20070901 |
| Pathogenesis of Alzheimer's disease. | Clinical interventions in aging 20070901 |
| Carboxylesterase in the liver and small intestine of experimental animals and human. | Life sciences 20070823 |
| Excited-state interactions in flurbiprofen-tryptophan dyads. | The journal of physical chemistry. B 20070809 |
| Multidrug resistance protein 1 (MRP1) in rabbit conjunctival epithelial cells: its effect on drug efflux and its regulation by adenoviral infection. | Pharmaceutical research 20070801 |
| An Aging Interventions Testing Program: study design and interim report. | Aging cell 20070801 |
| Flurbiprofen in the symptomatic management of rheumatoid arthritis: a valuable alternative. | International journal of clinical practice 20070801 |
| Cross-reaction allergic pancreatitis with ketoprofen and flurbiprofen. | Pancreas 20070801 |
| One-step preparation of drug-containing microparticles to enhance the dissolution and absorption of poorly water-soluble drugs using a 4-fluid nozzle spray drier. | Journal of controlled release : official journal of the Controlled Release Society 20070731 |
| Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver. | Drug metabolism and disposition: the biological fate of chemicals 20070701 |
| CYP2C9 protein interactions with cytochrome b(5): effects on the coupling of catalysis. | Drug metabolism and disposition: the biological fate of chemicals 20070701 |
| Binary polymeric blends to microencapsulate nitroflurbiprofen: physicochemical and in silico studies. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070701 |
| In vitro interaction studies of diltiazem with NSAID's using UV spectrophotometry and RP-HPLC techniques. | Pakistan journal of pharmaceutical sciences 20070701 |
| Simultaneous analysis of cytochrome P450 probes-dextromethorphan, flurbiprofen and midazolam and their major metabolites by HPLC-mass-spectrometry/fluorescence after single-step extraction from plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615 |
| Electrokinetic migration of acidic drugs across a supported liquid membrane. | Journal of chromatography. A 20070608 |
| Nanoparticles in modern medicine: state of the art and future challenges. | International journal of nanomedicine 20070601 |
| Mucoadhesive bilayered tablets for buccal sustained release of flurbiprofen. | AAPS PharmSciTech 20070601 |
| R-stereopreference analysis of lipase Novozym 435 in kinetic resolution of flurbiprofen. | Chirality 20070505 |
| Identification of flurbiprofen and its photoproducts in methanol by gas chromatography-mass spectrometry. | Biomedical chromatography : BMC 20070501 |
| Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to beta-amyloid peptides. | Journal of neuroscience research 20070501 |
| Traditional nonsteroidal anti-inflammatory drugs and postmenopausal hormone therapy: a drug-drug interaction? | PLoS medicine 20070501 |
| Structural and functional basis of cyclooxygenase inhibition. | Journal of medicinal chemistry 20070405 |
| Evaluation of flurbiprofen urinary ratios as in vivo indices for CYP2C9 activity. | British journal of clinical pharmacology 20070401 |
| In vitro and in vivo profiling of CHF5022 and CHF5074 Two beta-amyloid1-42 lowering agents. | Pharmacological research 20070401 |
| The aryl propionic acid R-flurbiprofen selectively induces p75NTR-dependent decreased survival of prostate tumor cells. | Cancer research 20070401 |
| Design and optimization of NSAID loaded nanoparticles. | Pakistan journal of pharmaceutical sciences 20070401 |
| Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib. | Molecular cancer therapeutics 20070401 |
| [A novel class of anti-inflammatory and analgesic drugs--NO-donating NSAIDs]. | Yao xue xue bao = Acta pharmaceutica Sinica 20070401 |
| Pharmacological characterization of receptor types mediating the dilator action of anandamide on blood vessels of the rat knee joint. | Life sciences 20070327 |
| Use of simple docking methods to screen a virtual library for heteroactivators of cytochrome P450 2C9. | Journal of medicinal chemistry 20070322 |
| Preadministration of flurbiprofen suppresses prostaglandin production and postoperative pain in orthopedic patients undergoing tourniquet inflation. | Journal of clinical anesthesia 20070301 |
| Ternary complexes of flurbiprofen with HP-beta-CD and ethanolamines characterization and transdermal delivery. | Drug development and industrial pharmacy 20070301 |
| [Very late intrastent thrombosis--at 27 months!]. | Archives des maladies du coeur et des vaisseaux 20070301 |
| Amyloid-beta vaccination, but not nitro-nonsteroidal anti-inflammatory drug treatment, increases vascular amyloid and microhemorrhage while both reduce parenchymal amyloid. | Neuroscience 20070209 |
| Factors affecting the formation of eutectic solid dispersions and their dissolution behavior. | Journal of pharmaceutical sciences 20070201 |
| Non-carboxylic analogues of arylpropionic acids: synthesis, anti-inflammatory activity and ulcerogenic potential. | European journal of medicinal chemistry 20070201 |
| Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portal hypertension in rats. | Gastroenterology 20070201 |
| Drug evaluation: (R)-flurbiprofen--an enantiomer of flurbiprofen for the treatment of Alzheimer's disease. | IDrugs : the investigational drugs journal 20070201 |
| Flurbiprofen: new indication. Lozenges: NSAIDs are not to be taken like sweets! | Prescrire international 20070201 |
| Gingival crevicular fluid prostaglandin E(2) and thiobarbituric acid reactive substance levels in smokers and non-smokers with chronic periodontitis following phase I periodontal therapy and adjunctive use of flurbiprofen. | Journal of periodontology 20070101 |
| Unilateral conjunctival chemosis as a unique symptom of nonsteroidal anti-inflammatory drug intolerance. | Journal of investigational allergology & clinical immunology 20070101 |
| Electrospray ionization/atmospheric pressure photoionization multimode source for low-flow liquid chromatography/mass spectrometric analysis. | Rapid communications in mass spectrometry : RCM 20070101 |
| Design and synthesis of some new thiazolo [3,2-b]-1,2,4-triazole-5(6H)-ones substituted with flurbiprofen as anti-inflammatory and analgesic agents. | Arzneimittel-Forschung 20070101 |
| Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer. | Breast cancer research : BCR 20070101 |
| Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice. | BMC neuroscience 20070101 |
| Emulsion of flurbiprofen axetil reduces propofol injection pain due to a decrease in free propofol concentration. | Journal of anesthesia 20070101 |
| Exploring effects of different nonsteroidal antiinflammatory drugs on lipid peroxidation. Part II. 4-HNE profile. | Acta poloniae pharmaceutica 20070101 |
| Modulation of hypericin photodynamic therapy by pretreatment with 12 various inhibitors of arachidonic acid metabolism in colon adenocarcinoma HT-29 cells. | Photochemistry and photobiology 20070101 |
| Functional evolution of the vitamin D and pregnane X receptors. | BMC evolutionary biology 20070101 |
| Molecular cloning and functional expression of esf gene encoding enantioselective lipase from Serratia marcescens ES-2 for kinetic resolution of optically active (S)-flurbiprofen. | Journal of microbiology and biotechnology 20070101 |
| Bortezomib in combination with celecoxib in patients with advanced solid tumors: a phase I trial. | BMC cancer 20070101 |
| Safety, tolerability, pharmacokinetics, and Abeta levels after short-term administration of R-flurbiprofen in healthy elderly individuals. | Alzheimer disease and associated disorders 20070101 |
| A tale of switched functions: from cyclooxygenase inhibition to M-channel modulation in new diphenylamine derivatives. | PloS one 20070101 |
| Assay principle for modulators of protein-protein interactions and its application to non-ATP-competitive ligands targeting protein kinase A. | Analytical chemistry 20061215 |
| CYP2C9 inhibition: impact of probe selection and pharmacogenetics on in vitro inhibition profiles. | Drug metabolism and disposition: the biological fate of chemicals 20061201 |
| Gene expression profiling in R-flurbiprofen-treated prostate cancer: R-Flurbiprofen regulates prostate stem cell antigen through activation of AKT kinase. | Biochemical pharmacology 20061115 |
| Flurbiprofen loaded biodegradable nanoparticles for ophtalmic administration. | Journal of pharmaceutical sciences 20061101 |
| Flurbiprofen and its nitric oxide-releasing derivative protect against septic shock in rats. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20061101 |
| Synthesis and pharmacological evaluation of some dual-acting amino-alcohol ester derivatives of flurbiprofen and 2-[1,1'-biphenyl-4-yl]acetic acid: a potential approach to reduce local gastrointestinal toxicity. | Chemistry & biodiversity 20061101 |
| Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine. | Drug metabolism and disposition: the biological fate of chemicals 20061001 |
| [Clinical observation of propofol combined with flurbiprofen axetil for induced abortion anesthesia]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20061001 |
| Phacoemulsification and acryl foldable intraocular lens implantation in dogs: 32 cases. | Journal of veterinary science 20060901 |
| Use of triplet excited States for the study of drug binding to human and bovine serum albumins. | ChemMedChem 20060901 |
| Molecular properties of flurbiprofen and its solid dispersions with Eudragit RL100 studied by high- and low-resolution solid-state nuclear magnetic resonance. | Pharmaceutical research 20060901 |
| Validation of incorporating flurbiprofen into the Pittsburgh cocktail. | Clinical pharmacology and therapeutics 20060901 |
| Osmotic flow through asymmetric membrane: a means for controlled delivery of drugs with varying solubility. | AAPS PharmSciTech 20060901 |
| Prophylaxis of migraine. | Neuropsychiatric disease and treatment 20060901 |
| Design and evaluation of colon specific drug delivery system containing flurbiprofen microsponges. | International journal of pharmaceutics 20060802 |
| Vancomycin as chiral selector for enantioselective separation of selected profen nonsteroidal anti-inflammatory drugs in capillary liquid chromatography. | Chirality 20060801 |
| Antioxidant activity and inhibition of human neutrophil oxidative burst mediated by arylpropionic acid non-steroidal anti-inflammatory drugs. | Biological & pharmaceutical bulletin 20060801 |
| Influence of age on flurbiprofen axetil requirements for preventing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, vehicle-controlled, parallel-group, dose-ranging study. | Clinical therapeutics 20060801 |
| Prevention of corneal neovascularization: evaluation of various commercially available compounds in an experimental rat model. | Cornea 20060801 |
| Study on the mechanism of photosensitive dermatitis caused by ketoprofen in the guinea pig. | Archives of toxicology 20060701 |
| Prostaglandin E2 and BDNF levels in rat hippocampus are negatively correlated with status epilepticus severity: no impact on survival of seizure-generated neurons. | Neurobiology of disease 20060701 |
| Pharmacokinetic parameters of (R)-(-) and (S)-(+)-flurbiprofen in dairy bovines. | Veterinary research communications 20060701 |
| Chamazulene carboxylic acid and matricin: a natural profen and its natural prodrug, identified through similarity to synthetic drug substances. | Journal of natural products 20060701 |
| In vitro interactions of captopril with NSAID's. | Pakistan journal of pharmaceutical sciences 20060701 |
| Factors involved in upregulation of inducible nitric oxide synthase in rat small intestine following administration of nonsteroidal anti-inflammatory drugs. | Digestive diseases and sciences 20060701 |
| Determination of ibuprofen and flurbiprofen in pharmaceuticals by capillary zone electrophoresis. | Journal of pharmaceutical and biomedical analysis 20060616 |
| Anti-inflammatory agents in the management of alimentary mucositis. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20060601 |
| In vivo and in vitro evaluation of essential oils from Ligusticum chuanxiong Hort on the transdermal delivery of flurbiprofen in rabbits. | Biological & pharmaceutical bulletin 20060601 |
| The effect of combinations of flurbiprofen, low molecular weight heparin, and doxycycline on the inhibition of corneal neovascularization. | Cornea 20060601 |
| In vitro metabolism of (nitrooxy)butyl ester nitric oxide-releasing compounds: comparison with glyceryl trinitrate. | The Journal of pharmacology and experimental therapeutics 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Brain uptake of nonsteroidal anti-inflammatory drugs: ibuprofen, flurbiprofen, and indomethacin. | Pharmaceutical research 20060501 |
| Improving the diagnosis and treatment of Alzheimer's disease. | Medicine and health, Rhode Island 20060501 |
| The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent. | Bioorganic & medicinal chemistry letters 20060415 |
| Mechanisms of the vasorelaxant effect of Danshen (Salvia miltiorrhiza) in rat knee joints. | Journal of ethnopharmacology 20060406 |
| Dynamic regulation of microglial functions by the non-steroidal anti-inflammatory drug NCX 2216: implications for chronic treatments of neurodegenerative diseases. | Neurobiology of disease 20060401 |
| Proton sensitivity Ca2+ permeability and molecular basis of acid-sensing ion channels expressed in glabrous and hairy skin afferents. | Journal of neurophysiology 20060401 |
| Nitric oxide-releasing flurbiprofen reduces formation of proinflammatory hydrogen sulfide in lipopolysaccharide-treated rat. | British journal of pharmacology 20060401 |
| Effect of cyclooxygenase inhibitors on the micturition reflex in rats: correlation with inhibition of cyclooxygenase isozymes. | BJU international 20060401 |
| Controlled porosity osmotic pump for the delivery of flurbiprofen. | Current drug delivery 20060401 |
| An epidural initial dose is unnecessary in combined spinal epidural anesthesia for Caesarean section. | Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20060401 |
| Comparison of the percutaneous absorption of hydrophilic and lipophilic compounds in shed snake skin and human skin. | Die Pharmazie 20060401 |
| [On the new guidelines for inhibitors of hemostasis and regional neuraxial anesthesia]. | Revista espanola de anestesiologia y reanimacion 20060301 |
| Characterization of the transdermal transport of flurbiprofen and indomethacin. | Journal of controlled release : official journal of the Controlled Release Society 20060221 |
| Ginkgo biloba does not alter clearance of flurbiprofen, a cytochrome P450-2C9 substrate. | Journal of clinical pharmacology 20060201 |
| Dual effect of flurbiprofen on cell proliferation and agonist-induced Ca(2+) movement in human osteosarcoma cells. | Basic & clinical pharmacology & toxicology 20060201 |
| Arachidonic acid activates phosphatidylinositol 3-kinase signaling and induces gene expression in prostate cancer. | Cancer research 20060201 |
| Drug nanoparticle formation from drug/HPMC/SDS ternary ground mixtures. | Die Pharmazie 20060201 |
| Preparation of submicron unilamellar liposomes by freeze-drying double emulsions. | Biochimica et biophysica acta 20060201 |
| Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies. | Clinical pharmacology and therapeutics 20060101 |
| Preparation and characterization of poly(D,L-lactic-co-glycolic Acid) microspheres containing flurbiprofen sodium. | Drug delivery 20060101 |
| Preoperative administration of intravenous flurbiprofen axetil reduces postoperative pain for spinal fusion surgery. | Journal of anesthesia 20060101 |
| Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo. | Molecular cancer 20060101 |
| Dyspnea assessment and adverse events during sputum induction in COPD. | BMC pulmonary medicine 20060101 |
| Pathological and physiological functions of presenilins. | Molecular neurodegeneration 20060101 |
| Mitochondrial oxidative damage in aging and Alzheimer's disease: implications for mitochondrially targeted antioxidant therapeutics. | Journal of biomedicine & biotechnology 20060101 |
| Determination of fourteen non-steroidal anti-inflammatory drugs in animal serum and plasma by liquid chromatography/mass spectrometry. | Rapid communications in mass spectrometry : RCM 20060101 |
| Atypical cytochrome p450 kinetics: implications for drug discovery. | Drugs in R&D 20060101 |
| The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease. | Journal of neuroinflammation 20060101 |
| Multi-residue determination of non-steroidal anti-inflammatory drug residues in animal serum and plasma by HPLC and photo-diode array detection. | Journal of chromatographic science 20060101 |
| Exploring effects of different nonsteroidal antiinflammatory drugs on malondialdehyde profile. | Acta poloniae pharmaceutica 20060101 |
| Non-steroidal anti-inflammatory drugs have anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro. | Neuropharmacology 20051201 |
| Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease. | PLoS medicine 20051201 |
| Anterior scleritis, scleral thinning, and intraocular pressure measurement. | Ocular immunology and inflammation 20051201 |
| 'In vitro' differences among (R) and (S) enantiomers of profens in their activities related to articular pathophysiology. | Inflammation 20051201 |
| Transmural gradient of leukocyte-endothelial interaction in the rat gastrointestinal tract. | American journal of physiology. Gastrointestinal and liver physiology 20051101 |
| Impact of CYP2C9 genotype on pharmacokinetics: are all cyclooxygenase inhibitors the same? | Drug metabolism and disposition: the biological fate of chemicals 20051101 |
| The unexpected side effects of new nonsteroidal anti-inflammatory drugs. | Expert opinion on emerging drugs 20051101 |
| Preparation of two-drug composite microparticles to improve the dissolution of insoluble drug in water for use with a 4-fluid nozzle spray drier. | Journal of controlled release : official journal of the Controlled Release Society 20051020 |
| Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001 |
| Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion. | Journal of medicinal chemistry 20050908 |
| Arachidonic acid, an omega-6 fatty acid, induces cytoplasmic phospholipase A2 in prostate carcinoma cells. | Carcinogenesis 20050901 |
| CYP2C9 genotype-dependent effects on in vitro drug-drug interactions: switching of benzbromarone effect from inhibition to activation in the CYP2C9.3 variant. | Molecular pharmacology 20050901 |
| Mechanisms of the dilator action of Danshen (Salvia miltiorrhiza) on rat isolated femoral artery. | Journal of cardiovascular pharmacology 20050901 |
| Poly(amidoamine) (PAMAM) dendritic nanostructures for controlled site-specific delivery of acidic anti-inflammatory active ingredient. | AAPS PharmSciTech 20050901 |
| Effects of non-ionic surfactants on isotachophoretic separations of 2-arylpropionic acids. | Journal of chromatography. A 20050819 |
| Experimental optimization of enzymic kinetic resolution of racemic flurbiprofen. | Biotechnology and applied biochemistry 20050801 |
| Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801 |
| Flurbiprofen and HCT1026 protect mice against acute pancreatitis-associated lung injury. | Shock (Augusta, Ga.) 20050801 |
| Effect of pore size of FSM-16 on the entrapment of flurbiprofen in mesoporous structures. | Chemical & pharmaceutical bulletin 20050801 |
| Involvement of endothelial cyclo-oxygenase metabolites in noradrenaline-induced contraction of rat coronary artery. | Clinical and experimental pharmacology & physiology 20050801 |
| Development of fast-dissolving tablets of flurbiprofen-cyclodextrin complexes. | Drug development and industrial pharmacy 20050801 |
| Triplet excited States as chiral reporters for the binding of drugs to transport proteins. | Journal of the American Chemical Society 20050727 |
| Encapsulation efficiency of water-soluble and insoluble drugs in liposomes prepared by the microencapsulation vesicle method. | International journal of pharmaceutics 20050714 |
| Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20050701 |
| Incidence of mucocutaneous reactions in children treated with niflumic acid, other nonsteroidal antiinflammatory drugs, or nonopioid analgesics. | Pediatrics 20050701 |
| Evaluation of a local anaesthesia regimen using a subphrenic catheter after gynaecological laparoscopy. | European journal of anaesthesiology 20050601 |
| Reversal of elution order for profen acid enantiomers in packed-column SFC on Chiralpak AD. | Chirality 20050515 |
| Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). | Journal of medicinal chemistry 20050505 |
| Flurbiprofen axetil preceded by venous occlusion in the prevention of pain on propofol injection in the hand: a prospective, randomized, double-blind, vehicle-controlled, dose-finding study in Japanese adult surgical patients. | Clinical therapeutics 20050501 |
| Dissolution, solubility, XRD, and DSC studies on flurbiprofen-nicotinamide solid dispersions. | Drug development and industrial pharmacy 20050501 |
| Development and validation of HPLC method for determination of indomethacin and its two degradation products in topical gel. | Journal of pharmaceutical and biomedical analysis 20050429 |
| Determination of stability constant values of flurbiprofen-cyclodextrin complexes using different techniques. | Journal of pharmaceutical and biomedical analysis 20050429 |
| Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. | Journal of medicinal chemistry 20050407 |
| A combined first principles computational and solid-state NMR study of a molecular crystal: flurbiprofen. | Physical chemistry chemical physics : PCCP 20050407 |
| UDP-glucuronosyltransferases and clinical drug-drug interactions. | Pharmacology & therapeutics 20050401 |
| Transgenic AD model mice, effects of potential anti-AD treatments on inflammation and pathology. | Brain research. Brain research reviews 20050401 |
| Activity of flurbiprofen and chemically related anti-inflammatory drugs in models of Alzheimer's disease. | Brain research. Brain research reviews 20050401 |
| Preparation and in vitro characterization of a semi-solid dispersion of flurbiprofen with Gelucire 44/14 and Labrasol. | Die Pharmazie 20050401 |
| Induction of apoptosis by R-flurbiprofen in human colon carcinoma cells: involvement of p53. | Biochemical pharmacology 20050301 |
| Cytochrome P-450 activity is differentially altered in severely injured patients. | Critical care medicine 20050301 |
| Synthesis of some new 2-(2-fluoro-4-biphenylyl)propionic acid derivatives as potential anti-inflammatory agents. | Die Pharmazie 20050301 |
| Pain control during fixed orthodontic appliance therapy. | The Angle orthodontist 20050301 |
| Ocular pharmacology of bicyclic hexahydroaporphines. | Methods and findings in experimental and clinical pharmacology 20050301 |
| Perioperative sonoclot analysis in patients given flurbiprofen. | European journal of anaesthesiology 20050301 |
| Molecule of the month. MPC-7869 (Flurizan). | Drug news & perspectives 20050301 |
| The addition of epidural morphine to ropivacaine improves epidural analgesia after lower abdominal surgery. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20050201 |
| Nuclear receptor peroxisome proliferator-activated receptor-gamma is activated in rat microglial cells by the anti-inflammatory drug HCT1026, a derivative of flurbiprofen. | Journal of neurochemistry 20050201 |
| The effect of systemic administration of ibuprofen in the experimental gingivitis model. | Journal of clinical periodontology 20050201 |
| Separation strategy for acidic chiral pharmaceuticals with capillary electrochromatography on polysaccharide stationary phases. | Electrophoresis 20050201 |
| Pharmacokinetics and synovial fluid concentrations of flurbiprofen enantiomers in horses: chiral inversion. | Journal of veterinary pharmacology and therapeutics 20050201 |
| NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives. | European journal of pharmacology 20050131 |
| Effect of combined use of nonionic surfactant on formation of oil-in-water microemulsions. | International journal of pharmaceutics 20050106 |
| Lack of specific amyloid-beta(1-42) suppression by nonsteroidal anti-inflammatory drugs in young, plaque-free Tg2576 mice and in guinea pig neuronal cultures. | The Journal of pharmacology and experimental therapeutics 20050101 |
| Clinical effects of flurbiprofen tooth patch on radiation-induced oral mucositis. A pilot study. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20050101 |
| Changes in mechanical, chemical, and thermal sensitivity of the cornea after topical application of nonsteroidal anti-inflammatory drugs. | Investigative ophthalmology & visual science 20050101 |
| Dual effect of isoprostanes on the release of [3H]D-aspartate from isolated bovine retinae: role of arachidonic acid metabolites. | Neurochemical research 20050101 |
| Effect of nonsteroidal anti-inflammatory drugs with varying extent of COX-2-COX-1 selectivity on urinary sodium and potassium excretion in the rat. | Canadian journal of physiology and pharmacology 20050101 |
| Study of the percutaneous penetration of flurbiprofen by cutaneous and subcutaneous microdialysis after iontophoretic delivery in rat. | Journal of pharmaceutical sciences 20050101 |
| Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines. | BMC pharmacology 20050101 |
| Formulation studies and in vivo evaluation of a flurbiprofen-hydroxypropyl beta-cyclodextrin system. | Pharmaceutical development and technology 20050101 |
| Sample pretreatment and determination of non steroidal anti-inflammatory drugs (NSAIDs) in pharmaceutical formulations and biological samples (blood, plasma, erythrocytes) by HPLC-UV-MS and micro-HPLC. | Current medicinal chemistry 20050101 |
| [Results of an open prospective controlled randomized comparative trial of flurbiprofen and paracetamol efficacy and tolerance in patients with throat pain]. | Terapevticheskii arkhiv 20050101 |
| The effects of non-steroidal anti-inflammatory drugs (selective and non-selective) on the treatment of periodontal diseases. | Current pharmaceutical design 20050101 |
| Pain management after lumbar spinal fusion surgery using continuous subcutaneous infusion of buprenorphine. | Journal of anesthesia 20050101 |
| Solid lipid nanoparticles bearing flurbiprofen for transdermal delivery. | Drug delivery 20050101 |
| Transdermal delivery of flurbiprofen: permeation enhancement, design, pharmacokinetic, and pharmacodynamic studies in albino rats. | Pharmaceutical development and technology 20050101 |
| Treatment of pseudophakic cystoid macular oedema. | Collegium antropologicum 20050101 |
| How to decrease pain at rapid injection of propofol: effectiveness of flurbiprofen. | Journal of anesthesia 20050101 |
| Effects of co-administered dexamethasone and diclofenac potassium on pain, swelling and trismus following third molar surgery. | Head & face medicine 20050101 |
| Long-term use of non-steroidal anti-inflammatory drugs and the risk of myocardial infarction in the general population. | BMC medicine 20050101 |
| Adjuvant arthritis-induced changes on ampicillin binding in serum and tissues under the influence of non-steroidal anti-inflammatory drugs in rats. | European journal of drug metabolism and pharmacokinetics 20050101 |
| Analgesic effect of sustained-release flurbiprofen administered at the site of tissue injury in the oral surgery model. | Journal of clinical pharmacology 20041201 |
| Pretreatment with flurbiprofen axetil and venous occlusion to reduce pain during injection of propofol. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20041201 |
| Enantioseparation of flurbiprofen and ketoprofen in patches and in urine excretions by achiral gas chromatography. | Archives of pharmacal research 20041201 |
| The cyclooxygenase inhibitor flurbiprofen reduces radiation-induced angiogenic growth factor secretion of squamous cell carcinoma cell lines. | Annals of the New York Academy of Sciences 20041201 |
| Excised porcine skin experimental systems to validate quantitative microdialysis methods for determination of drugs in skin after topical application. | Journal of controlled release : official journal of the Controlled Release Society 20041124 |
| A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes. | The Journal of pharmacology and experimental therapeutics 20041101 |
| Calculation of cyclodextrin binding affinities: energy, entropy, and implications for drug design. | Biophysical journal 20041101 |
| Evaluation of the bioavailability of flurbiprofen and its beta-cyclodextrin inclusion complex in four different doses upon oral administration to rats. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20041101 |
| Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action. | Journal of neurochemistry 20041101 |
| The potential role of non-steroidal anti-inflammatory drugs in treating Alzheimer's disease. | Expert opinion on investigational drugs 20041101 |
| Docking studies on NSAID/COX-2 isozyme complexes using contact statistics analysis. | Journal of computer-aided molecular design 20041101 |
| Selected non-steroidal anti-inflammatory drugs and their derivatives target gamma-secretase at a novel site. Evidence for an allosteric mechanism. | The Journal of biological chemistry 20041015 |
| The effects and metabolic fate of nitroflurbiprofen in healthy volunteers. | Clinical pharmacology and therapeutics 20041001 |
| Interactions between aspirin and COX-2 inhibitors or NSAIDs in a rat thrombosis model. | Fundamental & clinical pharmacology 20041001 |
| A simplified analytical method for a phenotyping cocktail of major CYP450 biotransformation routes. | Journal of pharmaceutical and biomedical analysis 20040903 |
| Cationic vesicles as chiral selector for enantioseparations of nonsteroidal antiinflammatory drugs by micellar electrokinetic chromatography. | Journal of chromatography. A 20040903 |
| The flurbiprofen derivatives HCT1026 and HCT1027 inhibit bone resorption by a mechanism independent of COX inhibition and nitric oxide production. | Bone 20040901 |
| Effect of camellia oil on the permeation of flurbiprofen and diclofenac sodium through rat and pig skin. | Biological & pharmaceutical bulletin 20040901 |
| The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution. | The Journal of biological chemistry 20040820 |
| Risk of breast cancer among users of aspirin and other anti-inflammatory drugs. | British journal of cancer 20040802 |
| Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation. | The Journal of biological chemistry 20040702 |
| Bioinversion of R-flurbiprofen to S-flurbiprofen at various dose levels in rat, mouse, and monkey. | Chirality 20040701 |
| S- but not R-enantiomers of flurbiprofen and ibuprofen reduce human microglial and THP-1 cell neurotoxicity. | Journal of neuroimmunology 20040701 |
| Characterisation of the rapid release of activin A following acute lipopolysaccharide challenge in the ewe. | The Journal of endocrinology 20040701 |
| NO-donating nonsteroidal antiinflammatory drugs (NSAIDs) inhibit colon cancer cell growth more potently than traditional NSAIDs: a general pharmacological property? | Biochemical pharmacology 20040615 |
| Effector-mediated alteration of substrate orientation in cytochrome P450 2C9. | Biochemistry 20040608 |
| Cyclooxygenase involvement in thromboxane-dependent contraction in rat mesenteric resistance arteries. | Hypertension (Dallas, Tex. : 1979) 20040601 |
| Replication of the Weber effect using postmarketing adverse event reports voluntarily submitted to the United States Food and Drug Administration. | Pharmacotherapy 20040601 |
| Influence of preparation methodology on solid-state properties of an acidic drug-cyclodextrin system. | The Journal of pharmacy and pharmacology 20040601 |
| HPLC microdetermination of flurbiprofen enantiomers in plasma with a glycopeptide-type chiral stationary phase column. | Biomedical chromatography : BMC 20040601 |
| A rabbit ear flap perfusion experiment to evaluate the percutaneous absorption of drugs. | International journal of pharmaceutics 20040519 |
| Fatty acids in Botryococcus braunii accelerate topical delivery of flurbiprofen into and across skin. | International journal of pharmaceutics 20040519 |
| Differential activation of CYP2C9 variants by dapsone. | Biochemical pharmacology 20040515 |
| Responsiveness of C-fiber nociceptors to punctate force-controlled stimuli in isolated rat skin: lack of modulation by inflammatory mediators and flurbiprofen. | Neuroscience letters 20040506 |
| Enantioseparation of hydrochloride salts using carbon dioxide-based mobile phases with on-line polarimetric detection. | Chirality 20040505 |
| Gastric tolerability and prolonged prostaglandin inhibition in the brain with a nitric oxide-releasing flurbiprofen derivative, NCX-2216 [3-[4-(2-fluoro-alpha-methyl-[1,1'-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl ester]. | The Journal of pharmacology and experimental therapeutics 20040501 |
| Renal expression of COX-2, ANG II, and AT1 receptor in remnant kidney: strong renoprotection by therapy with losartan and a nonsteroidal anti-inflammatory. | American journal of physiology. Renal physiology 20040501 |
| A nitric oxide releasing derivative of flurbiprofen inhibits experimental autoimmune encephalomyelitis. | Journal of neuroimmunology 20040501 |
| Nitroflurbiprofen (NicOx). | Current opinion in investigational drugs (London, England : 2000) 20040501 |
| Arachidonic acid metabolites and peroxide-induced inhibition of [3H]D-aspartate release from bovine isolated retinae. | Current eye research 20040501 |
| Resolution of indobufen enantiomers by capillary zone electrophoresis. Pharmacokinetic studies of human serum. | Journal of chromatography. A 20040402 |
| Differential roles of Arg97, Asp293, and Arg108 in enzyme stability and substrate specificity of CYP2C9. | Molecular pharmacology 20040401 |
| Nonsteroidal anti-inflammatory drug-induced liver injury: a case-control study in primary care. | Fundamental & clinical pharmacology 20040401 |
| The influence on human osteoblasts in vitro of non-steroidal anti-inflammatory drugs which act on different cyclooxygenase enzymes. | The Journal of bone and joint surgery. British volume 20040401 |
| Thermodynamics of solutions III: comparison of the solvation of (+)-naproxen with other NSAIDs. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20040301 |
| Acid-sensing ion channels (ASICs): new targets for the analgesic effects of non-steroid anti-inflammatory drugs (NSAIDs). | Current drug targets. Inflammation and allergy 20040301 |
| Subantimicrobial dose doxycycline efficacy as a matrix metalloproteinase inhibitor in chronic periodontitis patients is enhanced when combined with a non-steroidal anti-inflammatory drug. | Journal of periodontology 20040301 |
| Solvation and hydration characteristics of ibuprofen and acetylsalicylic acid. | AAPS pharmSci 20040301 |
| Manipulation of kinetic profiles in 2-aryl propionic acid cyclooxygenase inhibitors. | Bioorganic & medicinal chemistry letters 20040209 |
| Placing bets. National Institute on Aging committee chooses three compounds for definitive longevity testing. | Science of aging knowledge environment : SAGE KE 20040204 |
| Granulocyte colony-stimulating factor (filgrastim) treatment primes for increased ex vivo inducible prostanoid release. | The Journal of pharmacology and experimental therapeutics 20040201 |
| Modeling of adhesion in tablet compression. II. Compaction studies using a compaction simulator and an instrumented tablet press. | Journal of pharmaceutical sciences 20040201 |
| In vitro release and stereoselective disposition of flurbiprofen loaded to poly(D,L-lactide- co-glycolide) nanoparticles in rats. | Chirality 20040201 |
| Intravenous administration of flurbiprofen does not affect cerebral blood flow velocity and cerebral oxygenation under isoflurane and propofol anesthesia. | Anesthesia and analgesia 20040201 |
| Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration. | Neurobiology of disease 20040201 |
| Investigation of the release test method for the topical application of pharmaceutical preparations: release test of cataplasm including nonsteroidal anti-inflammatory drugs using artificial sweat. | Chemical & pharmaceutical bulletin 20040201 |
| Optimization of sample stacking for the simultaneous determination of nonsteroidal anti-inflammatory drugs with a wall-coated histidine capillary column. | Electrophoresis 20040201 |
| Possible involvement of the endocannabinoid system in the actions of three clinically used drugs. | Trends in pharmacological sciences 20040201 |
| Effect of nitric oxide releasing paracetamol and flurbiprofen on cytokine production in human blood. | European journal of pharmacology 20040112 |
| The 2.0 A resolution crystal structure of prostaglandin H2 synthase-1: structural insights into an unusual peroxidase. | Journal of molecular biology 20040109 |
| Endotoxin inhibits the surge secretion of gonadotropin-releasing hormone via a prostaglandin-independent pathway. | Endocrinology 20040101 |
| Modulation of beta-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures. | Journal of neurochemistry 20040101 |
| Arthritis medication studied for Alzheimer's disease prevention. | Mayo Clinic women's healthsource 20040101 |
| [Safety of a novel preparation -- strepfen -- for symptomatic treatment of pain in the throat]. | Vestnik otorinolaringologii 20040101 |
| Monolateral coxitis as a unique osteoarticular manifestation of Parvovirus B19 infection. | Clinical and experimental rheumatology 20040101 |
| In vitro proliferation of fibrosarcoma cells depends on intact functions of lipoxygenases and cytochrome P-450-monooxygenase. | Cancer investigation 20040101 |
| Lipid nano/submicron emulsions as vehicles for topical flurbiprofen delivery. | Drug delivery 20040101 |
| Cullen frontal sinus valved glaucoma shunt: preliminary findings in dogs with primary glaucoma. | Veterinary ophthalmology 20040101 |
| Topical NSAIDs for chronic musculoskeletal pain: systematic review and meta-analysis. | BMC musculoskeletal disorders 20040101 |
| Comparison between flurbiprofen and its nitric oxide-releasing derivatives HCT-1026 and NCX-2216 on Abeta(1-42)-induced brain inflammation and neuronal damage in the rat. | International journal of immunopathology and pharmacology 20040101 |
| Characterisation of the lowest singlet and triplet excited states of S-flurbiprofen. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040101 |
| [Results of an open prospective controlled randomized comparative trial of efficacy and tolerance of sublingual tablets flurbiprofen (strepfen) and paracetamol in patients with throat pain in acute infectious-inflammatory diseases of the upper respiratory tracts]. | Vestnik otorinolaringologii 20040101 |
| Reduction of Propofol-Induced Pain through Pretreatment with Lidocaine and/or Flurbiprofen. | Clinical drug investigation 20040101 |
| Thermodynamics of solutions IV: Solvation of ketoprofen in comparison with other NSAIDs. | Journal of pharmaceutical sciences 20031201 |
| Different in vitro activity of flurbiprofen and its enantiomers on human articular cartilage. | Farmaco (Societa chimica italiana : 1989) 20031201 |
| Effects of anti-inflammatory drugs on convulsant activity of quinolones: a comparative study of drug interaction between quinolones and anti-inflammatory drugs. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20031201 |
| Prednisolone and flurbiprofen drops to maintain mydriasis during phacoemulsification cataract surgery. | Journal of cataract and refractive surgery 20031201 |
| Noradrenaline-induced contraction mediated by endothelial COX-1 metabolites in the rat coronary artery. | Journal of cardiovascular pharmacology 20031201 |
| Inflammatory mediators do not stimulate CGRP release if prostaglandin synthesis is blocked by S(+)-flurbiprofen in isolated rat skin. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20031201 |
| An in vitro study of corpus cavernosum and aorta from mice lacking the inducible nitric oxide synthase gene. | Nitric oxide : biology and chemistry 20031201 |
| Contact dermatitis from peppermint and menthol in a local action transcutaneous patch. | Contact dermatitis 20031201 |
| Preparation and characterization of flurbiprofen beads by melt solidification technique. | AAPS PharmSciTech 20031201 |
| [Prescription of NSAIDs in patients treatment with platelet inhibitors or anticoagulants]. | Presse medicale (Paris, France : 1983) 20031122 |
| [Comparison of analgesic effects of intravenous flurbprofen and suppository indomethacin after laparoscopic cholecystectomy]. | Masui. The Japanese journal of anesthesiology 20031101 |
| P2Y2 receptor-stimulated release of prostaglandin E2 by rat inner medullary collecting duct preparations. | American journal of physiology. Renal physiology 20031001 |
| Inhibition of the rat hepatic microsomal flurbiprofen acyl glucuronidation by bile acids. | Journal of pharmaceutical sciences 20031001 |
| The comparison of efficacies of topical corticosteroids and nonsteroidal anti-inflammatory drops on dry eye patients: a clinical and immunocytochemical study. | American journal of ophthalmology 20031001 |
| 4'-hydroxylation of flurbiprofen by rat liver microsomes in fasting and feeding conditions. | Biological & pharmaceutical bulletin 20031001 |
| Evaluation of the contribution of cyclooxygenase 1 and cyclooxygenase 2 to the production of PGE2 and PGF2 alpha in epithelial cells from bovine endometrium. | Reproduction (Cambridge, England) 20031001 |
| Disposition of flurbiprofen in man: influence of stereochemistry and age. | Xenobiotica; the fate of foreign compounds in biological systems 20031001 |
| Stereospecific high-performance liquid chromatographic analysis of flurbiprofen: application to pharmacokinetic studies. | Journal of pharmaceutical and biomedical analysis 20030915 |
| Capillary electrophoresis with laser induced-fluorescence detection of profens derivatized with the water-soluble fluorogenic reagent 4-N-(4-N'-aminoethyl)piperazino-7-nitro-2,1,3-benzoxadiazole. | Journal of chromatography. A 20030905 |
| Characterisation of somatostatin actions on knee joint blood vessels of the rat. | European journal of pharmacology 20030808 |
| NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo. | The Journal of clinical investigation 20030801 |
| Unoprostone isopropyl ester darkens iris color in pigmented rabbits with sympathetic denervation. | Journal of glaucoma 20030801 |
| Simultaneous chiral discrimination of multiple profens by cyclodextrin-modified capillary electrophoresis in normal and reversed polarity modes. | Electrophoresis 20030801 |
| Thermodynamics of solutions. II. Flurbiprofen and diflunisal as models for studying solvation of drug substances. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030801 |
| Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration. | The Journal of pharmacology and experimental therapeutics 20030701 |
| Activation of c-Jun-N-terminal-kinase is crucial for the induction of a cell cycle arrest in human colon carcinoma cells caused by flurbiprofen enantiomers. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030701 |
| The influence of brain inflammation upon neuronal adenosine A2B receptors. | Journal of neurochemistry 20030701 |
| Thin layer chromatographic resolution of some 2-arylpropionic acid enantiomers using L-(-)-serine, L-(-)-threonine and a mixture of L-(-)-serine and L-(-)-threonine-impregnated silica gel as stationary phases. | Biomedical chromatography : BMC 20030701 |
| S+ -flurbiprofen but not 5-HT1 agonists suppress basal and stimulated CGRP and PGE2 release from isolated rat dura mater. | Pain 20030601 |
| Determination of the eicosanoid response to inflammatory stimuli in whole blood and its pharmacological modulation ex vivo. | Journal of immunological methods 20030601 |
| Addition of nitric oxide via nitroflurbiprofen enhances the material properties of early healing of young rat Achilles tendons. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030601 |
| Dextrans--potential polymeric drug carriers for flurbiprofen. | Die Pharmazie 20030601 |
| Stereoselective pharmacokinetics of flurbiprofen and formation of covalent adducts with plasma protein in adjuvant-induced arthritic rats. | Chirality 20030515 |
| Solubilization of flurbiprofen in pH-surfactant solutions. | Journal of pharmaceutical sciences 20030501 |
| Non-steroidal anti-inflammatory drugs inhibit nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes independent of cyclooxygenase activity. | The Journal of biological chemistry 20030425 |
| In vitro and in vivo evaluations of the efficacy and safety of skin permeation enhancers using flurbiprofen as a model drug. | International journal of pharmaceutics 20030414 |
| Modeling of adhesion in tablet compression--I. Atomic force microscopy and molecular simulation. | Journal of pharmaceutical sciences 20030401 |
| Differences in flurbiprofen pharmacokinetics between CYP2C9*1/*1, *1/*2, and *1/*3 genotypes. | European journal of clinical pharmacology 20030401 |
| Inhibition of nuclear factor-kappaB by a nitro-derivative of flurbiprofen: a possible mechanism for antiinflammatory and antiproliferative effect. | Antioxidants & redox signaling 20030401 |
| Mechanisms of vasorelaxation to testosterone in the rat aorta. | European journal of pharmacology 20030328 |
| Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase. | Journal of neuroscience research 20030315 |
| Anandamide metabolism by fatty acid amide hydrolase in intact C6 glioma cells. Increased sensitivity to inhibition by ibuprofen and flurbiprofen upon reduction of extra- but not intracellular pH. | Naunyn-Schmiedeberg's archives of pharmacology 20030301 |
| Flurbiprofen inhibits capsaicin induced calcitonin gene related peptide release from rat spinal cord via an endocannabinoid dependent mechanism. | Neuroscience letters 20030227 |
| [Diclofenac sodium or pred forte in the topical treatment of the fribrinous membrane after intraocular lens implantation in rabbits]. | Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20030227 |
| Activation of cytochrome P450 2C9-mediated metabolism: mechanistic evidence in support of kinetic observations. | Archives of biochemistry and biophysics 20030201 |
| Intrathecally applied flurbiprofen produces an endocannabinoid-dependent antinociception in the rat formalin test. | The European journal of neuroscience 20030201 |
| Acidic nonsteroidal anti-inflammatory drugs inhibit rat brain fatty acid amide hydrolase in a pH-dependent manner. | Journal of enzyme inhibition and medicinal chemistry 20030201 |
| Effect of enhancers and retarders on percutaneous absorption of flurbiprofen from hydrogels. | International journal of pharmaceutics 20030116 |
| Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors. | Journal of immunology (Baltimore, Md. : 1950) 20030115 |
| Effect of dextran as a run buffer additive in drug-protein binding studies using capillary electrophoresis frontal analysis. | Analytical chemistry 20030115 |
| Calcium-dependent synergistic interaction of platelet activating factor and epinephrine in human platelet aggregation. | Acta pharmacologica Sinica 20030101 |
| Tolbutamide, flurbiprofen, and losartan as probes of CYP2C9 activity in humans. | Journal of clinical pharmacology 20030101 |
| Enhancement of selectivity and resolution in the enantioseparation of uncharged compounds using mixtures of oppositely charged cyclodextrins in capillary electrophoresis. | Electrophoresis 20030101 |
| Topical nonsteroidal anti-inflammatory therapy in ophthalmology. | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20030101 |
| Formulation study and anti-inflammatory efficacy of topical semi-solids containing a nitro ester of flurbiprofen. | Skin pharmacology and applied skin physiology 20030101 |
| The stereospecificity of flobufen metabolism in isolated guinea pig hepatocytes. | BMC pharmacology 20030101 |
| Tranexamic acid: a review of its use in the management of menorrhagia. | Drugs 20030101 |
| Flurbiprofen, a unique non-steroidal anti-inflammatory drug with antimicrobial activity against Trichophyton, Microsporum and Epidermophyton species. | Letters in applied microbiology 20030101 |
| Modifications of clonidine binding to rabbit liver protein under the influence of non-steroid-anti-inflammatory drugs in vitro. | European journal of drug metabolism and pharmacokinetics 20030101 |
| Effects of non-steroidal anti-inflammatory drugs on cancer sites other than the colon and rectum: a meta-analysis. | BMC cancer 20030101 |
| Regulation of intraluteal production of prostaglandins. | Reproductive biology and endocrinology : RB&E 20030101 |
| Capillary electrochromatographic separation of non-steroidal anti-inflammatory drugs with a histidine bonded phase. | Journal of chromatography. A 20021227 |
| Contractile effect of anaphylatoxin C5a and of a mimetic peptide on the human umbilical artery: further evidence for leukocyte-dependent vasomotion. | Journal of cardiovascular pharmacology 20021201 |
| [The trends in new drugs for the prostate cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20021201 |
| Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2). | Biochemistry 20021112 |
| NO-flurbiprofen maintains duodenal blood flow, enhances mucus secretion contributing to lower mucosal injury. | American journal of physiology. Gastrointestinal and liver physiology 20021101 |
| Activation of CYP2C9-mediated metabolism by a series of dapsone analogs: kinetics and structural requirements. | Drug metabolism and disposition: the biological fate of chemicals 20021101 |
| Centrally administered galanin-like peptide modifies food intake in the rat: a comparison with galanin. | Journal of neuroendocrinology 20021101 |
| Selective inhibition of Abeta42 production by NSAID R-enantiomers. | Journal of neurochemistry 20021101 |
| Drug therapy of urinary urge incontinence: a systematic review. | Obstetrics and gynecology 20021101 |
| A nitric oxide-donating flurbiprofen derivative reduces neuroinflammation without interacting with galantamine in the rat. | European journal of pharmacology 20021025 |
| Efficient synthesis of alpha-aryl esters by room-temperature palladium-catalyzed coupling of aryl halides with ester enolates. | Journal of the American Chemical Society 20021023 |
| Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs. | The Journal of biological chemistry 20021011 |
| Thermodynamic study of the enantiomeric resolution of flurbiprofen by HPLC using Chiralpak AD-RH column. | Die Pharmazie 20021001 |
| Biochemical stabilization enhances red blood cell recovery and stability following cryopreservation. | Cryobiology 20021001 |
| Rapid and simple quantitative assay method for diastereomeric flurbiprofen glucuronides in the incubation mixture. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020825 |
| Metabolic profile of NO-flurbiprofen (HCT1026) in rat brain and plasma: a LC-MS study. | Life sciences 20020816 |
| Flurbiprofen-loaded acrylate polymer nanosuspensions for ophthalmic application. | Biomaterials 20020801 |
| Prostaglandin synthesis inhibitor affects humoral conditions and oxygen metabolism during normothermic cardiopulmonary bypass. | Artificial organs 20020801 |
| Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration. | Diabetes 20020801 |
| [The effectiveness of perioperative intravenous flurbiprofen in minor ear, neck and nose surgery]. | Masui. The Japanese journal of anesthesiology 20020801 |
| In vitro release studies of flurbiprofen from different topical formulations. | Drug development and industrial pharmacy 20020801 |
| The cannabinoids R(-)-7-hydroxy-delta-6-tetra-hydrocannabinol-dimethylheptyl (HU-210), 2-O-arachidonoylglycerylether (HU-310) and arachidonyl-2-chloroethylamide (ACEA) increase isoflurane provoked sleep duration by activation of cannabinoids 1 (CB1)-receptors in mice. | Neuroscience letters 20020705 |
| Characterization of the bone-resorptive effect of interleukin-11 in cultured mouse calvarial bones. | Bone 20020701 |
| Flurbiprofen does not change the bispectral index and 95% spectral edge frequency during total intravenous anaesthesia with propofol and fentanyl. | European journal of anaesthesiology 20020701 |
| Prevention by parenteral aspirin of indomethacin-induced gastric lesions in rats: mediation by salicylic acid. | Digestive diseases and sciences 20020701 |
| Peripheral analgesic sites of action of anti-inflammatory drugs. | International journal of clinical practice. Supplement 20020701 |
| Catalytic properties of rice alpha-oxygenase. A comparison with mammalian prostaglandin H synthases. | The Journal of biological chemistry 20020621 |
| ATP can enhance the proton-induced CGRP release through P2Y receptors and secondary PGE(2) release in isolated rat dura mater. | Pain 20020601 |
| In vivo activation of N-methyl-D-aspartate receptors in the rat hippocampus increases prostaglandin E(2) extracellular levels and triggers lipid peroxidation through cyclooxygenase-mediated mechanisms. | Journal of neurochemistry 20020601 |
| Lipids and nitric oxide in porcine retinal and choroidal blood vessels. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20020601 |
| Flurbiprofen release from Eudragit RS and RL aqueous nanosuspensions: a kinetic study by DSC and dialysis experiments. | AAPS PharmSciTech 20020601 |
| Preparation of solid dispersions of nonsteroidal anti-inflammatory drugs with acrylic polymers and studies on mechanisms of drug-polymer interactions. | AAPS PharmSciTech 20020601 |
| Demonstration of dose response of flurbiprofen lozenges with the sore throat pain model. | Clinical pharmacology and therapeutics 20020501 |
| Nitric oxide-releasing drugs: a novel class of effective and safe therapeutic agents. | Annals of the New York Academy of Sciences 20020501 |
| Affinity capillary electrophoresis using a low-concentration additive with the consideration of relative mobilities. | Analytical chemistry 20020415 |
| Polymorphic variants (CYP2C9*3 and CYP2C9*5) and the F114L active site mutation of CYP2C9: effect on atypical kinetic metabolism profiles. | Drug metabolism and disposition: the biological fate of chemicals 20020401 |
| [A simple method for determination of flurbiprofen in human plasma by gas chromatography-mass spectrometry]. | Masui. The Japanese journal of anesthesiology 20020401 |
| Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020315 |
| Identification of drug-binding sites on human serum albumin using affinity capillary electrophoresis and chemically modified proteins as buffer additives. | Electrophoresis 20020301 |
| Multidose flurbiprofen 8.75 mg lozenges in the treatment of sore throat: a randomised, double-blind, placebo-controlled study in UK general practice centres. | International journal of clinical practice 20020301 |
| Prediction of poly(ethylene) glycol-drug eutectic compositions using an index based on the van't Hoff equation. | Pharmaceutical research 20020301 |
| Prediction of selectivity for enantiomeric separations of uncharged compounds by capillary electrophoresis involving dual cyclodextrin systems. | Journal of chromatography. A 20020301 |
| Beneficial effects of NO-releasing derivative of flurbiprofen (HCT-1026) in rat model of vascular injury and restenosis. | Arteriosclerosis, thrombosis, and vascular biology 20020201 |
| Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2). | Journal of molecular graphics & modelling 20020101 |
| Nitric-oxide releasing molecules: a new class of drugs with several major indications. | Current pharmaceutical design 20020101 |
| The effect of nonsteroidal antiinflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma. | Cancer investigation 20020101 |
| Therapeutic utility of aspirin in the ApcMin/+ murine model of colon carcinogenesis. | BMC cancer 20020101 |
| Mechanism of in vitro release kinetics of flurbiprofen loaded ethylcellulose micropellets. | Acta poloniae pharmaceutica 20020101 |
| Prostaglandin synthesis inhibitor prevents hypotension without impairing gut perfusion during normothermic cardiopulmonary bypass. | ASAIO journal (American Society for Artificial Internal Organs : 1992) 20020101 |
| Pathogenic importance of intestinal hypermotility in NSAID-induced small intestinal damage in rats. | Digestion 20020101 |
| Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity. | Neurobiology of aging 20020101 |
| Separation and determination of diastereomeric flurbiprofen acyl glucuronides in human urine by LC/ESI-MS with a simple column-switching technique. | Drug metabolism and pharmacokinetics 20020101 |
| Elimination profiles of flurbiprofen and its metabolites in equine urine for doping analysis. | Talanta 20011224 |
| Estimation of acute flurbiprofen and ketoprofen toxicity in rat gastric mucosa at therapy-relevant doses. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20011201 |
| Differential effects of the nonsteroidal antiinflammatory drug flurbiprofen and its nitric oxide-releasing derivative, nitroflurbiprofen, on prostaglandin E(2), interleukin-1beta, and nitric oxide synthesis by activated microglia. | Journal of neuroscience research 20011115 |
| Validation of subcutaneous microdialysis sampling for pharmacokinetic studies of flurbiprofen in the rat. | Journal of pharmaceutical sciences 20011101 |
| Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients. | Immunopharmacology and immunotoxicology 20011101 |
| Interactive roles of superoxide and inducible nitric oxide synthase in rat intestinal injury provoked by non-steroidal anti-inflammatory drugs. | European journal of pharmacology 20011019 |
| Inhibition of human brain tumor cell growth by the anti-inflammatory drug, flurbiprofen. | Oncogene 20011018 |
| Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20011015 |
| Dominant role of an endothelium-derived hyperpolarizing factor (EDHF)-like vasodilator in the ciliary vascular bed of the bovine isolated perfused eye. | British journal of pharmacology 20011001 |
| Cyclooxygenase-independent actions of cyclooxygenase inhibitors. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011001 |
| Measurement of ketoprofen in horse urine using gas chromatography-mass spectrometry. | Journal of veterinary pharmacology and therapeutics 20011001 |
| The effect of flurbiprofen and tiaprofenic acid on serum cytokine levels of patients with osteoarthrosis. | Acta orthopaedica Scandinavica 20011001 |
| Nicotine-induced contraction in the rat coronary artery: possible involvement of the endothelium, reactive oxygen species and COX-1 metabolites. | Journal of cardiovascular pharmacology 20011001 |
| Effect of flurbiprofen on hind-limb suspension-induced bone loss. | Aviation, space, and environmental medicine 20010901 |
| Comparative evaluation of corneal epithelial permeability after the use of diclofenac 0.1% and flurbiprofen 0.03% after phacoemulsification. | Journal of cataract and refractive surgery 20010901 |
| Inhibition of bone resorption in vitro and prevention of ovariectomy-induced bone loss in vivo by flurbiprofen nitroxybutylester (HCT1026). | Arthritis and rheumatism 20010901 |
| Synthesis and receptor docking studies of N-substituted indole-2-carboxylic acid esters as a search for COX-2 selective enzyme inhibitors. | European journal of medicinal chemistry 20010901 |
| Palladium-catalyzed alpha-arylation of esters. | Journal of the American Chemical Society 20010822 |
| Minimal in vivo activation of CYP2C9-mediated flurbiprofen metabolism by dapsone. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010801 |
| Vasorelaxant effect of nitric oxide releasing steroidal and nonsteroidal anti-inflammatory drugs. | British journal of pharmacology 20010801 |
| Dapsone activation of CYP2C9-mediated metabolism: evidence for activation of multiple substrates and a two-site model. | Drug metabolism and disposition: the biological fate of chemicals 20010701 |
| Bradykinin-induced nociceptor sensitization to heat is mediated by cyclooxygenase products in isolated rat skin. | The European journal of neuroscience 20010701 |
| Peroxidase self-inactivation in prostaglandin H synthase-1 pretreated with cyclooxygenase inhibitors or substituted with mangano protoporphyrin IX. | The Journal of biological chemistry 20010608 |
| NO-flurbiprofen attenuates excitotoxin-induced brain inflammation, and releases nitric oxide in the brain. | Japanese journal of pharmacology 20010601 |
| Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations. | Biochemistry 20010501 |
| Chiral resolution of flurbiprofen and ketoprofen enantiomers by HPLC on a glycopeptide-type column chiral stationary phase. | Biomedical chromatography : BMC 20010501 |
| Proapoptotic anti-inflammatory drugs. | Urology 20010401 |
| Early clinical trials of chemopreventive and biologic agents: Designs, populations, and endpoints. | Urology 20010401 |
| Review: uveitis and immunosuppressive drugs. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010401 |
| [Convulsion following the combination of single preoperative oral administration of enoxacine and single postoperative intravenous administration of flurbiprofen axetil]. | Masui. The Japanese journal of anesthesiology 20010401 |
| Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine. | European journal of clinical pharmacology 20010401 |
| Modulation of prostaglandin H synthase activity by conjugated linoleic acid (CLA) and specific CLA isomers. | Lipids 20010401 |
| Selective inhibition of interleukin-4 gene expression in human T cells by aspirin. | Blood 20010315 |
| Interactions of inflammatory mediators stimulating release of calcitonin gene-related peptide, substance P and prostaglandin E(2) from isolated rat skin. | Neuropharmacology 20010301 |
| Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010301 |
| Perioperative intravenous flurbiprofen reduces postoperative pain after abdominal hysterectomy. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20010301 |
| Urethane anaesthesia could partly mask antinociceptive effects of non-steroidal anti-inflammatory drugs: a spinal c-Fos protein study. | Brain research 20010209 |
| Flurbiprofen enantiomers inhibit inducible nitric oxide synthase expression in RAW 264.7 macrophages. | Pharmaceutical research 20010201 |
| Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101 |
| Aortic hyporeactivity to norepinephrine induced by lipopolysaccharide in cirrhotic rats: beneficial effects of a non-steroidal anti-inflammatory drug coupled with a nitric oxide donor. | Journal of gastroenterology and hepatology 20010101 |
| Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulations. | BMC clinical pharmacology 20010101 |
| Using evidence from different sources: an example using paracetamol 1000 mg plus codeine 60 mg. | BMC medical research methodology 20010101 |
| Directed control of electroosmotic flow in nonaqueous electrolytes using poly(ethylene glycol) coated capillaries. | Electrophoresis 20010101 |
| Screening procedure for detection of non-steroidal anti-inflammatory drugs and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass spectrometry after extractive methylation. | Journal of analytical toxicology 20010101 |
| Protection by aspirin of indomethacin-induced small intestinal damage in rats: mediation by salicylic acid. | Journal of physiology, Paris 20010101 |
| Intracrevicular application of 0.3% Flurbiprofen gel and 0.3% Triclosan gel as anti inflammatory agent. A comparative clinical study. | Indian journal of dental research : official publication of Indian Society for Dental Research 20010101 |
| Prostaglandin synthesis inhibitor improves hypotension during normothermic cardiopulmonary bypass. | ASAIO journal (American Society for Artificial Internal Organs : 1992) 20010101 |
| Effects of epidural fentanyl and intravenous flurbiprofen for visceral pain during cesarean section under spinal anesthesia. | Journal of anesthesia 20010101 |
| Effect of endogenous and exogenous prostaglandin E(2) on interleukin-1 beta-induced cyclooxygenase-2 expression in human airway smooth-muscle cells. | American journal of respiratory and critical care medicine 20001201 |
| Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs. | Biochemical and biophysical research communications 20001130 |
| Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells. | Cancer research 20001015 |
| Mechanisms to prevent the toxicity of chronic neuroinflammation on forebrain cholinergic neurons. | European journal of pharmacology 20000818 |
| Prostaglandin E2 and the protein kinase A pathway mediate arachidonic acid induction of c-fos in human prostate cancer cells. | British journal of cancer 20000601 |
| R- and S-isomers of nonsteroidal anti-inflammatory drugs differentially regulate cytokine production. | European cytokine network 20000601 |
| Treatment and survival study in the C57BL/6J-APC(Min)/+(Min) mouse with R-flurbiprofen. | Life sciences 20000114 |
| Reactive oxygen species are involved in the apoptosis induced by nonsteroidal anti-inflammatory drugs in cultured gastric cells. | European journal of pharmacology 19991103 |
| Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. | Proceedings of the National Academy of Sciences of the United States of America 19990622 |
| Arachidonic acid and PGE2 regulation of hepatic lipogenic gene expression. | Journal of lipid research 19990601 |
| Interleukin-1 mediates a rapid inflammatory response after injection of adenoviral vectors into the brain. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19990215 |
| Structure-based design of COX-2 selectivity into flurbiprofen. | Bioorganic & medicinal chemistry letters 19990208 |
| Antinociceptive effects of S(+)-ketoprofen and other analgesic drugs in a rat model of pain induced by uric acid. | Journal of clinical pharmacology 19981201 |
| Comparative studies on the catalytic roles of cytochrome P450 2C9 and its Cys- and Leu-variants in the oxidation of warfarin, flurbiprofen, and diclofenac by human liver microsomes. | Biochemical pharmacology 19980715 |
| Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs. | American journal of veterinary research 19980401 |
| R-flurbiprofen chemoprevention and treatment of intestinal adenomas in the APC(Min)/+ mouse model: implications for prophylaxis and treatment of colon cancer. | Cancer research 19971001 |
| Differential effects of nonsteroidal anti-inflammatory drugs on constitutive and inducible prostaglandin G/H synthase in cultured bone cells. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19970801 |
| Portal venous transfusion up-regulates Kupffer cell cyclooxygenase activity: a mechanism of immunosuppression in organ transplantation. | Transplantation 19970715 |
| Membranous nephropathy associated with the use of flurbiprofen. | Clinical nephrology 19970401 |
| Serum protein binding of nonsteroidal antiinflammatory drugs: a comparative study. | Journal of pharmacokinetics and biopharmaceutics 19970201 |
| Induction of cyclo-oxygenase-2 mRNA by prostaglandin E2 in human prostatic carcinoma cells. | British journal of cancer 19970101 |
| Up-regulation of cyclooxygenase-2 by product-prostaglandin E2. | Advances in experimental medicine and biology 19970101 |
| Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10. | Xenobiotica; the fate of foreign compounds in biological systems 19961201 |
| New insights into the site and mode of antinociceptive action of flurbiprofen enantiomers. | Journal of clinical pharmacology 19960601 |
| Mediation by prostaglandins of the nitric oxide-induced neurogenic vasodilatation in rat skin. | British journal of pharmacology 19951101 |
| Protective effect of NO on gastric lesions and inhibition of expression of gastric inducible NOS by flurbiprofen and its nitro-derivative, nitroflurbiprofen. | British journal of pharmacology 19950901 |
| Flurbinitroxybutylester: a novel anti-inflammatory drug has enhanced antithrombotic activity. | Thrombosis research 19950701 |
| Prostanoid enhancement of interleukin-6 production by rat peritoneal mast cells. | Journal of immunology (Baltimore, Md. : 1950) 19950501 |
| Aspirin-like drugs can protect human T lymphocytes against benzoquinone cytotoxicity: evidence for a NAD(P)H:quinone reductase-dependent mechanism. | Archives of toxicology 19950101 |
| A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids. | Molecular pharmacology 19940101 |
| [Cholestasis caused by hypersensitivity to flurbiprofen]. | Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 19920801 |
| Renal papillary necrosis induced by flurbiprofen. | DICP : the annals of pharmacotherapy 19910101 |
| Flurbiprofen-associated acute tubulointerstitial nephritis. | American journal of nephrology 19910101 |
| Flurbiprofen and cutaneous vasculitis. | Annals of internal medicine 19900401 |
| Acute parkinsonism associated with flurbibrofen. | BMJ (Clinical research ed.) 19900224 |
| Simple procedure for measuring the pharmacodynamics and analgesic potential of lipoxygenase inhibitors. | Journal of pharmacological methods 19881201 |
| Pain suppression after pulpectomy with preoperative flurbiprofen. | Journal of endodontics 19870701 |
| A case of acute interstitial nephritis induced by flurbiprofen. | Japanese journal of medicine 19870501 |
| [Acute renal insufficiency caused by observed a combination of enalapril, furosemide and flurbiprofen in a patient with retroperitoneal fibrosis]. | Annales d'urologie 19870101 |
| Flurbiprofen in the treatment of juvenile rheumatoid arthritis. | The Journal of rheumatology 19861201 |
| Flurbiprofen, aspirin, codeine, and placebo for postpartum uterine pain. | The American journal of medicine 19860324 |
| A long-term study of flurbiprofen in rheumatological disorders: I. Rheumatoid arthritis. | The Journal of international medical research 19860101 |
| The effect of phenytoin, phenobarbitone, dexamethasone and flurbiprofen on misonidazole neurotoxicity in mice. | British journal of cancer 19840201 |
| A non-steroidal anti-inflammatory drug (flurbiprofen) to control idiopathic hypercalciuria resistant to dietary manipulation. | British journal of urology 19831201 |
| Side effects of non-steroidal anti-inflammatory drugs. | British medical journal (Clinical research ed.) 19820731 |
| Double-bind cross-over tiral of flurbiprofen and phenylbutazone in ankylosing spondylitis. | British medical journal 19741130 |
| Double-blind cross-over comparison of indomethacin, flurbiprofen, and placebo in ankylosing spondylitis. | Annals of the rheumatic diseases 19740301 |